LOCUS       NZ_CP072646            20879 bp    DNA     circular CON 02-DEC-2024
DEFINITION  Chloracidobacterium sp. MS 40/45 chromosome 1, complete sequence.
ACCESSION   NZ_CP072646
VERSION     NZ_CP072646.1
KEYWORDS    RefSeq.
SOURCE      Chloracidobacterium sp. MS 40/45
  ORGANISM  Chloracidobacterium sp. MS 40/45
            Bacteria; Pseudomonadati; Acidobacteriota; Terriglobia;
            Terriglobales; Acidobacteriaceae; Chloracidobacterium;
            Chloracidobacterium aggregatum.
REFERENCE   1  (bases 1 to 2667443)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Genomic and phenotypic characterization of Chloracidobacterium
            isolates provides evidence for multiple species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2667443)
  AUTHORS   Saini,M.K., Costas,A.M.G., Tank,M. and Bryant,D.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2021) Department of Biological Sciences, Tokyo
            Metropolitan University, 1-1, Minami-Osawa, Hachioji, Tokyo 1920397,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu 1.8 assembler v. 1.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018304805.1-RS_2024_12_02
            Annotation Date                   :: 12/02/2024 00:41:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,029
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,951
            CDSs (with protein)               :: 2,951
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 7 of 25
            Pseudo Genes (incomplete)         :: 18 of 25
            Pseudo Genes (internal stop)      :: 2 of 25
            Pseudo Genes (multiple problems)  :: 2 of 25
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:01:44
            NOTE :: This is a single region extracted from a cross-origin
            section of a larger, circular record.
            Orig. start                       :: 2651419
            Orig. end                         :: 4855
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072646.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     proto_core      10001..10879
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    477..490
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.6"
                     /tool="antismash"
     gene            1023..2453
                     /gene="cls"
                     /locus_tag="J8C02_RS11120"
                     /old_locus_tag="J8C02_11120"
     CDS             1023..2453
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014100732.1"
                     /locus_tag="J8C02_RS11120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11120"
                     /product="cardiolipin synthase"
                     /protein_id="WP_211426016.1"
                     /transl_table=11
                     /translation="MDAVWFEWTAFILFGVVGLIVSGHALLYKREARSALLWLLVVWFL
                     PVLGAVLYLLIGINRLQRRAQRLRDATALPPAAEQIAGEDQTELLADDDLGGLARLVQQ
                     VTGQPLLAGNHLTPLVNGVQAYPAMLDAIAQARHSIALATYIFDRDGIGDQFVHALLAA
                     QQRGVSIRILIDDVYVRLVRGSAFRFLKAAGLNVVSFNPPVLPARLHAANLRNHRKLLI
                     VDGQVGFTGGMNIHRPYWRPENPATAFRDLHFHVRGPVVRHMVETFTDDWYFTTGERLD
                     TRFWGEEGPQPAGPALARGIEAGPDETLDRLRWVFLGALNVARQSVRIWTPYFVPDQSL
                     LAALSAAALRGVEVDILTPVENNHPLVQWAGRAHYWQVLEHGAHIWERPGPFDHSKLMV
                     VDSRWVCIGSANWDARSLRLNFEFNLEVYDTALAQHLEALFQAARREATLVTAAQLRER
                     PLPIRLRDGAARLFSPML"
     gene            complement(2468..3793)
                     /locus_tag="J8C02_RS11125"
                     /old_locus_tag="J8C02_11125"
     CDS             complement(2468..3793)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1131: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014100733.1"
                     /locus_tag="J8C02_RS11125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11125"
                     /product="AmpG family muropeptide MFS transporter"
                     /protein_id="WP_211426017.1"
                     /transl_table=11
                     /translation="MSSPTVSPPSNWRTTLAPYLEGLTVRMLLLGFAAGLPLLLALSTL
                     SFRLREAGVDLTAIGYASWVGLVYGFKWCWSPLVDRMPLPGLTTRLGQRRGWLLLAQLA
                     VAGGLVGLALTDPRQALGRTVSFALFVAFASATQDIALDAYRIESADVTRQGILAAAYQ
                     TGYRLAMMWSSAGTLWIATRLGSRNGYDQFGWQAAYLVMAASMAVGVLTVLCSREPDTR
                     RVSVAGNLWAWLREALLEPFADFLRRYRWQAVLTLLLITTYRLSDTVLAVMVNPFYVDM
                     GYTKDQIAAVSNVYGVVMTLTGAFLGGVLVSRRGSLWPLWLGALLSSGTNLLFAALSLT
                     DPHLAALVVVISAEYLATGLASAAFVAYLSSLTNVGYSATQYALLSSMMLLLPKWAAGF
                     SGSAVATFGYTKFFVGTALLGLPAILLVSLALRFNRPATAQS"
     gene            complement(3854..6259)
                     /locus_tag="J8C02_RS11130"
                     /old_locus_tag="J8C02_11130"
     CDS             complement(3854..6259)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013618.5"
                     /locus_tag="J8C02_RS11130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11130"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_211426018.1"
                     /transl_table=11
                     /translation="MLTPERQRLLTRSAVFVALLTTLPTLPVPPGTTSDLPAPGPAETS
                     VSHAPFEARTATLRIQKAVDDRRYADALRDLAQFASAAPQLYTVNNYDYLRARLLHRTG
                     DLAGARTLYEQVMQRPGGQMFAPYCLKYLAELARQEAQSGNRAASRDEQRWLTELVQRF
                     GIHPAARSARLRLAESYATTGQLDRAIGLYRQMASQSREYEARLGVLLRRVGQETEAQT
                     LFRRLLATGKDDAALLAAEQLDAQGDTTLPPAQRLVRARLYLANRHTEGAKRHFRALVE
                     HVPAVPERPEALWSLGRAFFIEENWDEAIRWLDRTHEEYPTSPEGEKGCYQVGHALQNA
                     GRYQEAVARYEAFIAAYPNSEFLGGAHLNAIDALRLAGDPKAALEWCDRAEKRFPRELA
                     GVTARFQRAKIFMSQSNWRAALSVLEDMQRLPLHRRGPGSTNASEVTFLRGLCLERLER
                     FAEAIEVYLSLPDTRTSYYGQQATGRLLALAGNPKARALVAQQLGRFRQSQTKDGLHQA
                     LRLTPDPEVRRDLLGQLETVYRQLPAYARVWQVSVPEPGRQVILRAEAAPASRNLAEEL
                     SFLRLYDDALPFLEGGSGPALAQAVYAGRGNQAWKAMAYGEPTFGTLPEDFRLEVMPRL
                     VAELLYPAPYRDELVEHARRRGVDPRLLLAIARQESRFNPTVKSPVGARGMFQFIAATA
                     EQVAQKLGLPDVTQTDLYEPRFAIQFAAQYVADLFTLFPNHPAAVVAAYNGGETAVARW
                     CARAGADDQARFASEVGYAETKDYVFKVMTNYRCYRLLFDENLRPQQW"
     gene            6370..7287
                     /locus_tag="J8C02_RS11135"
                     /old_locus_tag="J8C02_11135"
     CDS             6370..7287
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014100737.1"
                     /locus_tag="J8C02_RS11135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11135"
                     /product="DUF4351 domain-containing protein"
                     /protein_id="WP_211426019.1"
                     /transl_table=11
                     /translation="MAYDNLCKYLAETYPAAFVRWLARHYPELPHEMEAAEIEVLKTEL
                     PVEPIRADFITFIRAAGVLLHIEFHLDPTSDPPLAFRMLDYWVRLFRRYRTPARQVVML
                     LKSTPAAQEMPGIFTAGMTHHGFHVLRLWEVDATELLDDEALLPLAVLGKAASDEALLR
                     ETAARVERMTDASQRANVSACAQVLAGLRFDRALIRALFREEAMRESVIYQEIIERGLA
                     QGVERGLAQGSHLEAIRLARTLLERRFGPLPESITAQIALLSREQAESLAIETLNFDSL
                     DAVRTWLAVQPTASEATENPSKPS"
     gene            complement(7298..8620)
                     /locus_tag="J8C02_RS11140"
                     /old_locus_tag="J8C02_11140"
     CDS             complement(7298..8620)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014100738.1"
                     /locus_tag="J8C02_RS11140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11140"
                     /product="5'-deoxyadenosine deaminase"
                     /protein_id="WP_211426020.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1e-73, bitscore:
                     245.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTLRIVNGTLLTGGPHHQVINGDLYVQDGRITHLGKVPETAGET
                     LDASGCVVIPGFVQSHIHLCQTLFRGAADDLELLDWLKTRIWKFEAAHTPESLRVSAQL
                     AVAEMMSGGTTCAMTMESVHHTEAALEVVAETGFRAVVGKCLMDAGDEVPPGLRETTAH
                     ARTESLRLLDAWHGQAGGRIQMAFAPRFVLSCTETLLREVAALAREKGVRIHTHASENR
                     DEVALVERLTGRRNLAHLHALGLTGPHVGIAHCIWLDETELELLAETGTHVLHCPSSNL
                     KLGSGIAKVVEMLERSISVSLGADGAPCNNRLDAFTEMRTAALLQKMRCGAQKLTALDA
                     FQMATWQGARALGLEDEIGSLEVGKAADIAVVTLDTLHAAPHPDPLSALVYAAMASDVR
                     HVVIAGRVVVRDGALTALDATETRAQARREFAALAARAGVA"
     gene            complement(8625..9893)
                     /locus_tag="J8C02_RS11145"
                     /old_locus_tag="J8C02_11145"
     CDS             complement(8625..9893)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020804.5"
                     /locus_tag="J8C02_RS11145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11145"
                     /product="small ribosomal subunit Rsm22 family protein"
                     /protein_id="WP_211426021.1"
                     /transl_table=11
                     /translation="MNASTLMNNDLLQHVERHLVGRWLGPEALAQYDRGPVGKVFLRST
                     ASALVRLSDDFTRERQNLAETPPGDYWHDTRRLAYLFHFLPRNYVKAAWMLDELGRHAD
                     VVKNLAAKTRFTILDVGCGPGTSALATMSFLAALQPAAFQVRIVLVEMSPAALQKATDL
                     LRQAADWLNAGRHEAMTLHVTPHTGDAKSTGKYPPHAAADFIWLSNVLNECAPEEDPPA
                     AWVRELVRDHLAPEGSLCVIEPALHASARAAMQLRDALLADHPEWGIFAPCTADGPCRM
                     LAGRPERDWCHVALTWQPTPLVAQLDAMTGLSSRVQKFFYFVLRRDGKRATEVRPGWTP
                     WRVIGDLQREKGREKRLVCGPDRCTLLTRFKRDRHSGNEAFSTAMRGDVLWLSSAPAPL
                     ADGLRLLPHIQVERQAVASPTTE"
     gene            10001..10879
                     /locus_tag="J8C02_RS11150"
                     /old_locus_tag="J8C02_11150"
     CDS             10001..10879
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014100740.1"
                     /locus_tag="J8C02_RS11150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11150"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_211426022.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.7e-60, bitscore:
                     200.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAYFAEKVPEVNRWLDRLMPPVTTPPPRIHEAMRYSLMAGGKR
                     LRPILVLAAGEVFGGAPERLYPVACAFEMVHTYSLIHDDLPAMDNDDLRRGMPTCHKQF
                     DEATAILAGDGLMTHAFRILAEMDAPAEQKVRVIRELAVGSGTVEGMIAGQVVDLEAEG
                     KPIDAGRLAFIHRAKTGALIRGALVCGGIVADAAESDLALLSAYGDRVGLAFQIADDIL
                     DETATAEQLGKTPGKDAAAGKATYPALYGLEASRKQAESLAEEAIEVLVPLGQRAELLI
                     EMARFVVHRTS"
     gene            10949..11509
                     /locus_tag="J8C02_RS11155"
                     /old_locus_tag="J8C02_11155"
     CDS             10949..11509
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF020123.5"
                     /locus_tag="J8C02_RS11155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11155"
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_211426023.1"
                     /transl_table=11
                     /translation="MRHITSWFLVLFLAAGTSVAATQSGVKRDTPRPGNPTSEEAAPAP
                     DFTVPSLTDDTSIRLSSLRGKVVVMNFWASWCPPCRAEFPLLAKLHNQYKERDVVLLSL
                     NLAEEAETARHFIQQAAPPFPVYAGAIAAAKYNASRLPTTYFIDRAGRIRRQVSGFHPK
                     RTEAEFSSLIDELLAEPAPVAQP"
     misc_feature    10994..11007
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            11515..13134
                     /locus_tag="J8C02_RS11160"
                     /old_locus_tag="J8C02_11160"
     CDS             11515..13134
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016289.5"
                     /locus_tag="J8C02_RS11160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11160"
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_211426024.1"
                     /transl_table=11
                     /translation="MSRPAAPYRFLTACFVLLVLAGFGGSLPLPSNLDAVSVVQLKRHL
                     SFLASAELGGRYTLSAGNRIAARYLAAQLEAFGYRGAATDGSFFQKIPFVMRTGGQDSK
                     LTLEGAPKPFVHGEDFILRDPAATLPNLSLEAEMVFVGYGVSHPKTDAYQTVNAEGRIV
                     LCLASGTPDVLAGESLPNDWREKAALEHGAQAMLLIPDEKLAEGWAQAAAYVRRRSVPR
                     VRPKASAAKPEQPAIPAFLLSPSAAESFLSPFNLTLAQVHEAARTGAALPSVAAQRRCT
                     IRTTENERVEYSQNVVGILDGADPGLKQEFVVLSAHYDHLPAQGDVIFPGADDDGSGTA
                     AVLELARVFAEGERPKRSIFILFNTGEEMGLLGSGYFTDQEPLVPLEAIVANFNIDMIG
                     RSRPPGDDRRENAELTDRDSVFLIGPDKHSRQLFELSEQTNAATVQLRLDYTYNDEAHP
                     MRLFYRSDHWNFAKRGIPIVFYFTGLHADYHRPTDTVDKIDFEKMARITKLVYATAWRT
                     ANREQRFDLDVWKSRERATPNR"
     gene            complement(13237..13572)
                     /locus_tag="J8C02_RS11165"
                     /old_locus_tag="J8C02_11165"
     CDS             complement(13237..13572)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J8C02_RS11165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J8C02_11165"
                     /product="hypothetical protein"
                     /protein_id="WP_211426025.1"
                     /transl_table=11
                     /translation="MRQVMLVSLAMMLLSLPVWAAKRKRETQIPRDCVVQGQEVKTGNY
                     TLEYDDEQPGELIIRSGSREVARTSYTLVELPKPATADTVVFTNKDGARKIARIEMKGS
                     KMALQIG"
     misc_feature    complement(13762..13775)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.94"
                     /tool="antismash"
     gene            13831..14496
                     /locus_tag="J8C02_RS11170"
                     /old_locus_tag="J8C02_11170"
     CDS             13831..14496
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="J8C02_RS11170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11170"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_211426026.1"
                     /transl_table=11
                     /translation="MKCPLTVGSELGIALPKQERSRRTREKLILAAAQLFEERGFEKTT
                     SNDIAAAAGVSIGSFYAYFSDKRQILLLLFEQLIAERLDAVFSNFTEEDLTGGDLRGCI
                     ERCIHRTFANKAATPGLTRLIYDLAPKDEAVGALCRRLMEDSVENLEKLLRKAMALGLT
                     GLTDPHTAATTIVHAAEAVARKCVFEDELPEKDWTPYITCLTDMTYGFVFGAGSQLPA"
     gene            complement(14765..15748)
                     /locus_tag="J8C02_RS11175"
                     /old_locus_tag="J8C02_11175"
     CDS             complement(14765..15748)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03436.1"
                     /locus_tag="J8C02_RS11175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_11175"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_211426027.1"
                     /transl_table=11
                     /translation="MTGTKLWLVTGVILAMLQGTSLGLIGQERAPKRPQRPNPSAAQDE
                     VFNIDTSLVVLDVAVFDQDNRFVGDLRKENFRVYDEQVEQQIEYFSRDEAPVSLGFVVD
                     TSGSMRPRRTKVVEAVKFLARAAKSGDEFFLVDFKNKAELAEEFTPRPADIEDAVDNIV
                     WGGGTALLDAIQLSAEYADKEGKNRRKAIVVFSDGDERDSYYDRRQMLKLLQEYQVQVY
                     IVGFPDEDDNGGLFGRSTRKRSVQLIKDIAGETGGRAFFPKTLDELPEIVRAINADLRT
                     QYSIGFVPSQDQPQSGGFRRITVRAEDGKRKLVVRTRSGYTPRKGD"
     misc_feature    15742..15758
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    complement(15940..15955)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     region          1..20879
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20879
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20879
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:10879](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     gene            16028..17419
                     /gene="dnaA"
                     /locus_tag="J8C02_RS00005"
                     /old_locus_tag="J8C02_00005"
     CDS             16028..17419
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003688 - DNA replication origin binding
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /GO_process="GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dnaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014098519.1"
                     /locus_tag="J8C02_RS00005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_00005"
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="WP_211427028.1"
                     /transl_table=11
                     /translation="MDDDKWTSFLGEIERRINHESFSTWFKPVTLQACQGDTIYLRVPN
                     RSYEDWITETYHEYVEEALKAVGCSGARLVFVYTESPEPKSANGLLDDDHPKSGKDAFS
                     FGVFDSDLSEGLAGTRIVDLEPLELPLNPKYTFETFVVGSCNQFARAAAMAVADTPTRT
                     YNPLFIYGGVGLGKTHLMHAIGHAIRNRDRHMRLVYISSEKFMNELINAIRYDKAQAFR
                     EKYRSIDVLLIDDIQFIAGKERTQEEFFHTFNALYDAQKQIVISSDCPPREIPTLEERL
                     HSRFEWGLIADLQPPDLETKVAILKRKADLEKIDLSDNVALFIAGKIKSNIRELEGSLI
                     RLVAYASLRHRPIDIELCKEVLNIEEEERPITIEMIQRVVSDHYGLRVADLKSKNNSRN
                     IAVPRQVAMYLCKQLTNHSLPEIGRHFGNKHHTTVLHSCEKISRLYQTQNDFHRLINNL
                     ISSLK"
     gene            complement(17694..19346)
                     /locus_tag="J8C02_RS00010"
                     /old_locus_tag="J8C02_00010"
     CDS             complement(17694..19346)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014587.5"
                     /locus_tag="J8C02_RS00010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_00010"
                     /product="Ppx/GppA phosphatase family protein"
                     /protein_id="WP_211426028.1"
                     /transl_table=11
                     /translation="MPAAPRQSISPRPGSALHRVAAIDVGSNSIHLIIAEARPGERLRI
                     IEREKDTVRLAAGLTETHHLTDEKIKAAVATLRRFTDLAHAHDVTAVLVVATSAIREAW
                     NREVFLQRVEQEIGLKVEILPGVEEARLIALAVAEVTDFQGERGLIIDVGGGSTEFILT
                     DGQTPAYLASVKLGAVRLQEQFLSRQDPPSRAEIEALTTYIQSGLARTVREIQEAGGFQ
                     RVVGTSGTILALAAAKPDTRSLETKAPAPKKVAFTSFASELTYAELQALNRRLQRMPHK
                     ARRKLPGVDSRRADIIVAGGILLETIFRELGIQHLTTCEWSLREGVVINYLREQGWSLS
                     HTPLSAGDIRERSILSVARRYAYEAGHAHHTARLAEQIFDQTLPLHGLGMREREWLRCA
                     ALLHDIGYHIAHTSHHKHAMYLIRHAELPGFHPHEIAIIANLARYHRGSLPKRKHEDFT
                     RLLPVHQETVTRLIPILRLADALDRRHGGKVKEVIVEMQDQSLQIVPIPVDNTDISLEV
                     WCAQQVLPIWATVFPGLKAQICLERAARTAAYR"
     gene            19604..20377
                     /locus_tag="J8C02_RS00015"
                     /old_locus_tag="J8C02_00015"
     CDS             19604..20377
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014098521.1"
                     /locus_tag="J8C02_RS00015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J8C02_00015"
                     /product="carbonic anhydrase"
                     /protein_id="WP_246604616.1"
                     /transl_table=11
                     /translation="MSSPRHTFERRLACCCFAPLMALAFVHPTAIAQSKSPAKPAVSQP
                     AVTPEEKTPKSTPALTNEQLQADPEAALKVLLEGNRRFAAGETIHPRQDIARIRETAKG
                     QKPFAIIIGCSDSRVPNEIVFDQGLGDLFIVRTAGQVSTYSSWGSIEFAEEVLGAKLIF
                     VLGHTKCGAVQAAVRVPEVPGHIVTLINDIKPAAQRVKGQPGDEVENAVRENVRTQVEK
                     LKNLEPVLAKRFREGKLKIVGGVYDIDTGLITLVE"
ORIGIN
        1 gacaggtgca gtacgtgccc ccttccgcgc gctacctggc acggatcggc gagctgcttg
       61 acctcgaccg cctgcgcgcc ttcgacggcg aagtgctcgt ggactcgatg tacggcgctg
      121 gcggacgcta catcgagcag ttgctccagg gcggacggct gcgcgtcacc accctgcgcg
      181 ccgagcggga cccctacttt ggcggcattc acccggagcc gatgatgccg cagctccaac
      241 ccctgtgtga tgaggtggtc cgccgccggg cctttctggg actggcaacg gatggcgatg
      301 ctgaccgtat cggcgcggtg gatgacaccg gcgcttacct gaacacccac cgcatgctgg
      361 ccattctggc gctgtatctc atccgcaagc gcggactgac cggcggcatt gcccggacgg
      421 tttcccaaag tgtcgtcgtc aaacgcattg ccgagcgcca cgggctgcca acctatgaaa
      481 cgcccgttgg cttcaagcac attgccgccc tgatgcgaac ccacgacatc ctgtgtggcg
      541 gcgaggaatc caacggcctg ggctgcaaac tgcacatccc ggagcgggac ggcatcttca
      601 gcgggctgct ctttctggaa gccattctgg cctttggcag gaagccgtcc gagctggtgg
      661 ctgacatttc ggaggagttt ggattttttg cctacgaccg gcgcgacctg gcgcttgacc
      721 acatcgagca gggattggcg ttcatcgagc gcctgaaagc cgacccgccg gcggctgtcg
      781 ccgggtatcc ggtgcgcgag gtgggactgc tcgacggcgt gaaactccac ttcgaggacg
      841 aaagctggct gctgttccgg gcttcgggca ctgagccgtt ggtgcgcgtc tatagcgagg
      901 ccacgaccgt cgaaaagatg tcggcgctgc tggctttcgg cgaacagttg gtgcacgagt
      961 cactttgacg atgtggacag gcaggtggcg acagccgccc ttccacgaaa gaagccgggc
     1021 gaatggacgc cgtttggttt gaatggacag cgtttatcct cttcggtgtc gttggtctca
     1081 tcgtctccgg gcacgcgctg ctctacaaac gcgaagcacg ctcggccctg ctgtggctgc
     1141 tcgtcgtctg gtttctgccg gttctgggcg cggtactcta tctgctgatc ggcatcaacc
     1201 gcctccagcg ccgcgcccag cgtctccggg acgccacggc cctgccaccg gcggctgaac
     1261 agattgccgg tgaagaccaa accgaactgc tggcggatga tgacttgggt ggactggcgc
     1321 ggcttgtcca acaggtcaca ggacaaccgc tgctggccgg aaatcacctc acgccactgg
     1381 tcaacggtgt gcaggcctat ccggccatgc ttgacgccat cgcccaggcc cggcacagca
     1441 tcgccctggc cacctacatt ttcgaccgcg acggcatcgg cgaccagttt gtacacgctc
     1501 tgctggcagc acagcagcgt ggcgtcagca tccgcattct catagacgat gtgtatgtgc
     1561 gcctggtacg cggctcagcc ttcaggtttc tcaaagccgc cgggctgaat gtggtctctt
     1621 tcaacccgcc ggtacttccg gcgcggcttc acgccgccaa cctgcgcaat caccgcaagc
     1681 tgctcattgt ggacggccag gttggcttta ccggcggcat gaatatccac cgcccctact
     1741 ggcggccgga aaatccggcg acggcctttc gtgacctgca ctttcacgtc cgggggccgg
     1801 tcgtccgcca catggtggaa accttcaccg acgactggta cttcaccact ggcgaacgcc
     1861 tggataccag gttctggggg gaggaaggcc cccaaccggc cggaccggca ctggcgcgcg
     1921 gcatcgaagc cggcccggat gaaacccttg accgcctgcg gtgggtcttt ctgggcgcgc
     1981 tgaatgtggc gcggcagagc gtcagaatct ggacgcctta tttcgtcccc gaccagtccc
     2041 ttctggccgc attgagtgcg gcggcgctgc gtggtgtcga agtggacatc ctgacgccgg
     2101 ttgaaaacaa ccatccgctg gttcagtggg ccggacgggc gcactactgg caggtacttg
     2161 aacacggagc gcacatctgg gaacgccccg gcccgtttga ccacagcaag ctcatggttg
     2221 tggacagtcg ctgggtgtgc atcggttcag ccaactggga tgcccgcagc ctgcggctca
     2281 actttgagtt caacctggaa gtctatgaca cggccctggc gcagcatctg gaggcgctgt
     2341 tccaggcggc ccgccgggaa gccacactgg ttaccgctgc ccaactccgg gagcgtccgc
     2401 tgccgattcg cctgcgtgac ggtgcggcgc ggctgttctc tccgatgctg tagggccgcc
     2461 ggctcggtca gctttgcgcc gtcgcagggc ggttgaagcg cagcgccagc gacaccagca
     2521 gaatcgccgg aagaccgagc agcgctgtgc cgacaaaaaa ctttgtgtag ccaaacgtcg
     2581 ccacggccga tcccgaaaaa cctgccgccc actttggcaa cagcaacatc atcgagctaa
     2641 gcagggcata ctgcgttgcc gagtatccga cgttcgtcag cgacgacagg taggcgacaa
     2701 aggccgccga agccagcccc gtggcgagat attccgcaga aatgaccacg accagcgccg
     2761 ccaggtgcgg gtccgtgaga ctgagcgccg caaagaggag attcgtgccg ctgctcagca
     2821 gggcccccag ccacagcggc cacaagctcc cccggcgcga caccagaacc ccacccagga
     2881 aggcgccggt gagcgtcatg acgacgccat agacgttgct tacggctgca atctggtctt
     2941 tcgtgtaacc catgtccacg taaaacgggt tgaccatcac ggccagaacg gtatcgctca
     3001 ggcggtaggt cgtgatgagc agcagcgtca gcaccgcctg ccagcggtaa cggcgcagaa
     3061 aatcggcaaa cggttcgagg agggcttcgc gcagccacgc ccaaaggttt ccggcaacag
     3121 agacgcgccg ggtgtccggt tcgcgcgaac acaggaccgt aagcacacca actgccattg
     3181 aagccgccat gacaaggtag gccgcctgcc agccaaactg gtcatagccg ttacggctgc
     3241 caagccgggt ggcgatccag agcgtcccgg cgctgctcca catcatggcc agccggtagc
     3301 cggtctggta ggccgcggcc agaatgcctt ggcgcgtcac atcggcagat tcgatgcggt
     3361 aggcatcgag ggcaatatcc tgggtagccg aggcaaaggc cacaaacagc gcaaagctga
     3421 cggttcgccc cagcgcctga cgcggatcgg tcagcgcgag gcccacaagg ccgcccgcca
     3481 cggcaagctg cgccaacaac agccagcccc ggcgctggcc gagccgtgtc gtcagtccgg
     3541 gaagcggcat gcggtcaacc agcggcgacc aacaccactt gaaaccatag accagtccaa
     3601 cccaactggc gtaaccgatg gcggtcaggt caacgcccgc ctcgcgcagc cgaaagctca
     3661 gtgtgctgag cgccagcagc aacggcagcc cggccgcaaa gccaaggagg agcatccgta
     3721 cggtcagccc ttcaaggtag ggcgccagcg tcgtgcgcca gtttgaaggc ggagaaacag
     3781 tcggagatga caacggcgtg ggctgaagcc gggaaccaga cctgcaacgc cggcccggct
     3841 ccggttgctg gtttcaccac tgctgcgggc gcaggttttc gtcaaacaac agccgatagc
     3901 agcggtagtt ggtcatgacc ttgaaaacat agtccttggt ttcggcatag ccgacttcag
     3961 aagcaaagcg cgcctggtcg tccgcaccgg cccgtgcgca ccagcgcgcc acagcggtct
     4021 caccgccatt gtatgccgcg acaacggctg ccggatggtt gggaaacaag gtaaacaaat
     4081 cggccacata ctgggccgca aactgtatgg caaagcgtgg ttcgtagagg tccgtctggg
     4141 tcacgtccgg cagccccagc ttttgggcaa cctgttccgc cgtggcagcg atgaactgaa
     4201 acatgccgcg cgcgccgacc ggtgatttga cggtgggatt gaaacgcgat tcctgccggg
     4261 caatggccag caacagacgt gggtccacac cacgccgccg cgcatgttca accagttcat
     4321 cgcggtaggg cgcagggtaa agcagttcgg ccacaaggcg cggcatgact tccagccgga
     4381 agtcttccgg cagcgtgcca aatgtcggct ctccgtaagc catcgctttc cacgcctgat
     4441 tgccacgtcc ggcatagacg gcctgagcca gcgccggccc gctgccgcct tccagaaagg
     4501 gcagggcgtc gtcgtagaga cggagaaagg atagttcttc agccagattg cggctcgccg
     4561 gagcggcctc ggcgcggaga atcacctgcc ggcccggttc gggcacgctg acctgccaga
     4621 cgcgggcata ggctggaagc tggcgataga cggtttcaag ctggcccagc aggtcacgcc
     4681 gcacctccgg gtcaggcgtc aggcgaagtg cctgatgcag cccatccttg gtctggctct
     4741 ggcggaagcg gccgagttgc tgggccacga gggcccgggc tttggggttt ccggccagcg
     4801 ccagaagccg cccggtggct tgctggccgt agtagctcgt ccgggtgtcg ggcagcgaaa
     4861 gatagacttc gatggcttcc gcgaagcgct ccaggcgttc cagacacaga ccgcgcagga
     4921 aggtgacttc gctggcgttg gtcgaaccgg ggccgcgccg gtgcagcggc agacgttgca
     4981 tgtcttccag cacactgagc gccgcgcgcc agttgctctg ggacatgaaa atctttgccc
     5041 gttgaaagcg cgccgtaaca ccggccagct cacgcgggaa gcgtttttct gcacggtcac
     5101 accattcaag cgccgccttg ggatcgccag ccagacgcag cgcgtcaatg gcattgaggt
     5161 gggcgccgcc gagaaactca ctgttgggat aggccgcgat gaaggcttcg taacgcgcaa
     5221 cggcttcctg gtaacgtccg gcattctgga gagcgtgtcc gacctggtaa cagccttttt
     5281 cgccttccgg tgacgtggga tattcctcgt gcgtgcggtc cagccagcgg atggcttcat
     5341 cccagttttc ctcgataaag aaagcgcgcc ccaggctcca cagggcttca ggacgctctg
     5401 gaacggccgg gacatgctcc accagcgcgc ggaaatggcg ttttgcgcct tcggtgtggc
     5461 gattggccag atagagccgg gcgcgcacca ggcgctgggc tggcggcaag gtggtgtctc
     5521 cctgggcatc aagctgttcg gccgccagca gggccgcatc atcttttccg gtggccagca
     5581 gccgccggaa cagcgtctgc gcctctgttt cctggccaac ccggcgcagg agcacgccga
     5641 gccgggcctc atattcacgg ctttgggaag ccatctggcg atacagccca atggcgcggt
     5701 caagctgtcc cgttgtcgcg tagctttcgg ccagacgcag gcgggcgctg cgtgcggccg
     5761 gatggattcc gaaccgctgc acaagctcgg tcagccagcg ttgttcatcg cggctggcag
     5821 cccggttgcc ggactgggct tcctgacgcg ccaactcggc caggtatttc aggcagtacg
     5881 gtgcgaacat ctgcccgccg gggcgttgca tgacctgttc atacagggtt ctggcgcctg
     5941 ccagatcgcc ggtgcggtgg agcaggcgcg cccgcagata atcgtagttg ttgaccgtgt
     6001 agagctgcgg cgcagcactg gcaaactggg cgagatcgcg cagcgcatcg gcataacgcc
     6061 ggtcatccac ggccttctgg atgcggagcg ttgccgttcg ggcctcgaat ggcgcgtggg
     6121 agacggatgt ttcagccggg ccgggcgccg gaaggtcaga agtcgtaccg ggcggcacgg
     6181 gcagcgtcgg aagggttgtc agcagggcga caaagacggc gctgcgggtc agcaggcgtt
     6241 gtctttcggg cgtgagcatg gtgacatccg ttgagaactg tccctgggcg cgtcctggtt
     6301 gcagcaacgg ccaccgctga agtaccgcgt atggcgtggt gactccgggg acctgggtga
     6361 gcaaaggcaa tggcgtatga caacctgtgc aagtacctgg cagaaaccta tccggcggct
     6421 ttcgtccgct ggctggccag gcattatcct gagcttccac acgaaatgga agccgccgag
     6481 atcgaggttc tcaaaaccga actgcccgtt gagccgattc gcgccgactt catcaccttc
     6541 atccgggccg caggcgtgct tctgcacatc gagtttcatc tcgacccgac ctccgacccg
     6601 cccctggcat ttcggatgct ggactactgg gtgcgtcttt ttcgccgcta ccgcactccg
     6661 gcccggcagg ttgtcatgtt gctgaaaagt acgccggcgg cccaggagat gcccggcatc
     6721 ttcacagccg gtatgacgca ccatggtttc cacgtgctgc gcctgtggga ggtggatgcc
     6781 accgaacttc tggatgatga ggctctattg ccgctggctg tcctcggaaa ggcggcctcc
     6841 gatgaggcgc tgctgcggga aaccgcggcg cgggttgaac ggatgacaga cgccagccaa
     6901 cgcgctaacg tgtcagcctg tgcgcaggtg ctggccggac tgcggtttga ccgggcgttg
     6961 attcgggctt tatttcggga ggaagccatg cgggaatccg tcatctacca ggaaatcatc
     7021 gaacgtggac tggcgcaggg tgtcgaacgc gggctggcac agggcagtca cctggaagcc
     7081 atcaggctgg cccgcacgct gctcgaacgc cgctttggcc cgctcccgga aagcatcacc
     7141 gcccagattg ccctgctgtc acgggaacag gccgaaagtc tggccatcga gaccctgaac
     7201 ttcgacagcc tcgacgcggt acgtacctgg ctggccgtcc aacccacagc ttccgaagcg
     7261 acagaaaacc cgtccaaacc ctcgtaacgg ccaggcttca cgccacaccg gcccgtgccg
     7321 ccagggcggc aaactcgcgc cgggcctggg cccgcgtctc tgtggcgtcg agtgccgtca
     7381 acgccccgtc gcggacgacg acgcgaccgg cgatgaccac atgccgtacg tcggaggcca
     7441 tggccgcata aaccagcgcc gaaagcgggt caggatgtgg cgcggcatgc agggtgtcga
     7501 gcgtcacgac ggctatatcg gccgcttttc ccacttcaag gctgccaatt tcatcctcca
     7561 gtccaagcgc ccgcgccccc tgccatgtcg ccatctgaaa ggcgtcgagc gcggtgagtt
     7621 tctgcgcgcc acagcgcatt ttctgaagca gtgcggctgt ccgcatttcc gtgaaggcat
     7681 caagccggtt gttgcacggt gcgccgtcgg cgcccaggga aactgaaatg ctgcgctcca
     7741 gcatttccac gactttggcg atgccggagc cgagtttcag gtttgaagac ggacagtgca
     7801 gcacgtgggt tccggtctct gccaaaagct ccagctcggt ctcgtcaagc cagatacagt
     7861 gcgcgatgcc gacgtgggga ccggtcaggc ccagcgcgtg caggtgcgcc aggtttcgcc
     7921 gtccggtcag acgttcgacc agcgccactt catcccggtt ttctgaagcg tgtgtgtgga
     7981 tgcgtacgcc cttttcacgc gccagggccg ccacctcccg caacagcgtt tcggtgcacg
     8041 acaaaacgaa gcggggcgca aaggccattt gaatccgtcc cccggcctgg ccgtgccagg
     8101 cgtcgagaag gcggagggat tcggtacgcg catgcgccgt cgtctcacga aggcccggag
     8161 gcacttcatc gccggcatcc atcaggcact tcccgacaac cgcgcgaaaa ccggtttcgg
     8221 cgacgacctc cagggcagct tccgtgtggt ggacgctttc catggtcatg gcgcatgtcg
     8281 tcccgccgga catcatttcc gcaacggcga gttgcgccga aacacggagg ctttccggcg
     8341 tgtgggccgc ctcgaacttc cagatgcgcg ttttcagcca gtcgagaagt tcgagatcat
     8401 cggccgcacc ccgaaacagg gtctggcaca ggtgaatgtg cgattggaca aaacccggta
     8461 tcaccacaca cccggaggca tcgagcgtct ccccggccgt ttcggggact ttgcccaggt
     8521 gggtgatgcg gccgtcctgc acatacaggt cgccgttgat gacctggtgg tgcgggccgc
     8581 ccgtgagcag cgtgccgttg acaatccgca gggtcggcat ggttttactc cgtcgtgggt
     8641 gaggctacgg cctggcgctc gacctggatg tgcggcagca accgcagccc atcggccaag
     8701 ggcgccggcg ccgacgaaag ccacaggaca tcaccccgca tggccgtgct gaaggcttca
     8761 ttgccgctgt ggcggtcacg cttgaagcgc gtcagaagcg tacagcggtc agggccacag
     8821 acaagccgtt tttcacgtcc cttttcacgc tggaggtcac caatgacgcg ccacggcgtc
     8881 cagccgggac ggacttctgt cgcgcgtttt ccatcccgcc gcagcacgaa gtaaaaaaac
     8941 ttctggacgc gactggacag cccggtcatc gcatcgagct gtgcgacgag cggcgttggt
     9001 tgccaggtca gcgcgacatg acaccagtca cgctccggtc gcccggccag catccgacat
     9061 ggcccgtctg ccgtgcatgg cgcaaagatt ccccattccg gatggtctgc aagaagcgcg
     9121 tcacgaagct gcatggcggc acgcgcactt gcgtgcaggg ccggctcaat gacacacaaa
     9181 ctgccctccg gtgcaaggtg atccctgacc agttcccgca cccaggcagc cggcgggtct
     9241 tcctccgggg cgcactcgtt gagaacgttg gaaagccaga tgaaatcagc cgcagcgtgc
     9301 ggtgggtact tgcccgtact tttggcatcg ccggtgtgtg gcgtcacgtg cagcgtcatg
     9361 gcctcatgac gcccggcatt gagccaatcg gcggcctgcc gcagcaggtc cgtcgctttc
     9421 tggagggcgg ctggcgacat ctcgacaagg acgatccgca cctgaaacgc cgccggctgc
     9481 aacgccgcca gaaacgacat ggttgccagg gcggaagttc ccggtccaca gccaacatcc
     9541 agaatggtga accgggtttt ggcagcgagg ttcttcacaa catcggcatg cctgcccagt
     9601 tcgtccagca tccaggcggc tttgacatag ttgcgcggca aaaagtggaa cagataggcc
     9661 agacggcgcg tgtcgtgcca gtaatctccc ggaggggttt cagccaggtt ctggcgctcc
     9721 cgggtaaaat catcggaaag acgcaccagg gcactggccg ttgaacgcag aaacacttta
     9781 ccgaccggcc cacggtcgta ctgggccagc gcctccgggc caagccaacg tcccaccaga
     9841 tggcgctcca cgtgctgcaa caagtcgttg ttcatcaggg tgctggcgtt catggtctgc
     9901 cgggacgcag gccccttccg gggaagtggt tgttttgccc ggcaaggccg cttatcgttg
     9961 caagtcctga tttcacctgc cgggagcatg gaagcgccct atgattgaag cctacttcgc
    10021 ggaaaaggtt cccgaagtca accgctggct tgaccgactc atgccgccag tcacgacccc
    10081 tccgccgcgt attcacgaag ccatgcgata cagtctgatg gccggcggca agcggctccg
    10141 ccccatactt gtgcttgccg ctggtgaggt ttttggtggc gcaccagagc ggctctatcc
    10201 ggtggcctgt gcctttgaga tggttcatac ctattctctc atccacgatg acctgccggc
    10261 catggacaac gacgacctgc ggcggggcat gcccacctgc cacaagcagt tcgatgaagc
    10321 gaccgccatt ctggctggag atggactgat gacccatgcc tttcggattc tggccgaaat
    10381 ggatgcccct gccgaacaga aagtgcgggt catccgggag ctggccgtcg ggtccggcac
    10441 cgtcgagggc atgatagccg gccaggtcgt tgacctcgaa gccgaaggaa aacccattga
    10501 cgccgggcgg ctggcgttca ttcaccgggc caagaccggt gcgctcatcc gtggggcgct
    10561 ggtttgcggc gggattgtcg ccgacgccgc cgaaagcgat ctggcgctgc tgtccgctta
    10621 cggcgaccgg gtggggctgg ccttccagat tgccgatgac attctcgatg aaacagccac
    10681 ggctgagcag ttgggcaaaa cccccggcaa agatgcggcg gccggcaagg ccacctatcc
    10741 ggcgctttac gggctggagg cttcgcggaa acaggccgag tccctggctg aggaagccat
    10801 cgaggtgctt gtgccgctcg gccaacgggc ggaactgctc atcgaaatgg cgcgctttgt
    10861 cgtacaccgc acgtcgtagc ccggccggcg cggggctgcc cggtgcttct ttgtctttca
    10921 ctttcgtctg tccttgtgga gaggttctat gcgacacatc acgagttggt ttctggtgct
    10981 gtttctggcc gcaggcactt ccgttgccgc cacccagtcc ggggtcaagc gggatactcc
    11041 ccgccccgga aacccgactt ccgaagaggc ggcgccggcg ccggatttca cggtgccaag
    11101 cctgaccgat gacacctcca tccgcctttc ttccctgcgc ggcaaggtgg tggtcatgaa
    11161 cttctgggca agctggtgtc cgccctgccg cgccgaattc ccgcttctgg caaagctcca
    11221 taaccagtac aaggaacggg atgtcgtcct gttgtcgctc aacctggccg aagaggccga
    11281 aacggcgcgt catttcatcc agcaggcagc gccgcccttc cccgtgtatg ccggcgccat
    11341 cgccgccgcc aagtacaatg cttcacggct gccgacgacc tatttcattg accgggccgg
    11401 gcgcatccgg cggcaggttt ccggttttca tcccaagcgc acggaagctg aattctccag
    11461 cctcattgat gagcttctgg ccgagccggc cccggtggcc caaccatgaa agccatgtca
    11521 agaccggctg cgccataccg cttcctgacc gcgtgcttcg tcctgctcgt tctggctggc
    11581 tttggcggct cgttgccgct tccgtccaac ctggatgccg tcagtgtcgt tcaactcaaa
    11641 cgacatcttt cctttctggc ctcagccgag cttggcgggc gctataccct cagcgccggc
    11701 aatcgtattg cggcgcgtta tctggctgcc cagctcgaag ccttcggcta ccggggggcg
    11761 gccaccgatg gctcgttttt ccagaaaatt ccatttgtaa tgcgaaccgg cgggcaggac
    11821 tcaaagctta cgctggaggg tgctcccaaa cccttcgttc atggcgaaga tttcattctg
    11881 cgcgatccgg cggcaaccct gcccaatctg tccctggaag ctgagatggt ctttgtcggg
    11941 tatggggtat cccacccgaa aaccgatgcc taccagacgg tcaacgccga gggacggatc
    12001 gttctctgcc tggcaagtgg cacgccggac gttctggcgg gggaaagcct gcccaatgac
    12061 tggcgtgaga aagcggctct ggagcatggc gcacaagcca tgttgttgat cccggacgaa
    12121 aaactggctg agggttgggc gcaggcagcg gcttacgtcc gccgccggtc cgttccgcgg
    12181 gtgcgcccga aagcctcggc tgcaaagcca gagcagccag ccatccctgc ctttctgctg
    12241 agtccgtccg cggctgagtc ctttctgtcc ccgttcaatc tcaccctggc acaggttcat
    12301 gaggcagcca gaaccggtgc agcattgcca tccgttgctg cccagcgccg ctgtaccatc
    12361 cgcacgaccg aaaacgaacg ggttgagtac agccagaatg tcgtcggtat cctcgatggc
    12421 gctgaccccg ggctcaaaca ggagtttgtt gtcctcagcg cccactatga ccacctgccg
    12481 gcgcagggtg acgtcatctt tcccggagcc gacgacgacg gctccggcac ggcagccgtt
    12541 ctggagctgg cccgggtgtt tgccgaaggt gagcgcccaa aacgctcgat cttcatcctg
    12601 ttcaacaccg gcgaggaaat gggactgctc ggctcaggct actttaccga ccaggaaccg
    12661 ctcgtgccgc tggaagccat tgtggcgaac ttcaacattg acatgatcgg ccgctcccgc
    12721 ccgcccggtg acgaccggcg tgaaaatgcc gaactgaccg accgcgacag tgtcttcctc
    12781 atcgggccgg acaaacacag ccgccagctc tttgagctga gcgagcagac caatgccgcc
    12841 acggttcagc ttcggcttga ctacacctac aatgacgaag cacatccgat gcggctcttt
    12901 taccgcagcg accactggaa cttcgccaag cgcggcatcc ccattgtttt ctatttcacc
    12961 ggcctgcatg ccgactacca ccgaccgacc gacacggtgg acaagattga tttcgagaaa
    13021 atggcccgca tcaccaaact ggtctatgca acggcctggc gaacggccaa ccgtgagcag
    13081 cgtttcgacc tcgatgtgtg gaaaagccgg gagcgcgcca caccgaaccg gtaattccgg
    13141 actgaaaaca gacaggctgg caacttccca accggtgtcg cggccagcct gtccttgtcc
    13201 ggttgcctgt cggcagaaca cggatgtccg gccgggctat ccaatctgaa gtgccatttt
    13261 ggagcctttc atttcgatgc gggcaatttt gcgggcgcca tccttgtttg tgaacaccac
    13321 cgtgtcggct gtcgccggct tcggcaactc gaccagggta tagcttgtcc gggcgacttc
    13381 ccggctgccg ctccgaataa tcaactcccc gggttgttcg tcgtcgtact caagcgtgta
    13441 gttgcccgtt ttcacttcct gcccctgcac gacgcaatcc cgtggaatct gcgtctcccg
    13501 cttccgtttg gcagcccaaa cgggaaggct caacaacatc atggccagag aaaccaacat
    13561 gacctgtcgc atggctttca ctcctcttgt caaccgcggc gcggcttcgt ggggtatgtc
    13621 tgatctgaca tgaacctgag ttttggttca catcgcctat acgacaagaa tatgagtttg
    13681 ggttcatatt ttacaatccc ctttttccga accttccccg tcgcatccga aaacccggcc
    13741 ccaaaaatgt cttggaagcg gcacacaacc gtttgctagg atggagtgcc aacctgaccg
    13801 gtatctccag tacggatcat gaacgcgcct atgaaatgtc ctctgaccgt tggttcagag
    13861 cttggaatcg cattaccaaa gcaggaacgc agccgtcgca cccgcgaaaa gctcatcctg
    13921 gctgccgcac agctcttcga ggaacgaggt tttgagaaaa caacctccaa cgacattgcg
    13981 gctgccgccg gtgtcagcat tggatcgttt tatgcctact tctcagacaa gcggcagatt
    14041 ctgcttctgc tgtttgagca gctcattgcc gaacgcctgg atgccgtctt cagcaatttc
    14101 accgaagaag acctgaccgg cggcgatctt cggggctgta tcgaacgctg cattcaccgc
    14161 acctttgcca acaaggcggc gacgccgggg ctgacccgtc tcatctacga tttagccccc
    14221 aaggatgaag ccgttggggc gctgtgccgg cgcctgatgg aagattcggt ggaaaacctt
    14281 gagaagctgc tccgcaaggc catggcgctg ggacttacag gcctgaccga cccgcacacg
    14341 gcagcgacaa ccatcgtcca cgctgccgaa gccgttgccc gcaaatgtgt ctttgaagat
    14401 gaattaccgg agaaggactg gacgccttat atcacctgtc tgacggatat gacctatggc
    14461 tttgtctttg gcgccgggtc tcaacttccg gcataaaggc cggcagcgtg cctgcaagtg
    14521 ctcagggaaa gactggttag acgctttttc cacaagtttt ccacaggctt cctttttttc
    14581 tcccgacgaa aaggctttgg atacatagct ccaaatacaa gtaaaaaaaa gatttaccct
    14641 caaagctcat ccagccggga aggctcgggg ggctgactgg agctgttacc ccgtggtttt
    14701 ccacaagttt tccacaggtg ggcgcgtccg ttatccacag ttgctgacga ccttggcggg
    14761 ttgatcagtc acctttgcgc ggggtgtagc cggagcgggt acgtaccacg agtttgcgtt
    14821 ttccgtcttc agcccggacc gtgatgcgcc ggaagccgcc actctgcggc tggtcctgac
    14881 ttggaacaaa tccaatcgaa tactgggtac gcaaatcggc attgatggca cgcacgatct
    14941 ccgggagctc gtccagtgtc ttcgggaaaa aggcacgccc gccggtttca ccggcaatgt
    15001 ccttgatgag ctggacggaa cgcttccgcg tcgagcggcc gaacaaacct ccgttgtcat
    15061 cctcatcggg gaagccaacg atatagacct gcacctgata ctcctggagc agcttgagca
    15121 tctgccggcg gtcatagtag ctgtcgcgct cgtcgccatc ggagaagacg acaattgcct
    15181 tgcggcggtt tttgccctcc ttgtcggcat actcggcaga aagctgaatg gcatcgagca
    15241 gggcggttcc accgccccac acgatgttgt ccacggcgtc ctcgatgtcc gccggccggg
    15301 gcgtaaactc ctcggccagc tcagctttgt tcttgaaatc caccaggaag aactcatcgc
    15361 ctgactttgc tgcacgtgcg agaaacttga cggcttcgac cacttttgtc cgccgtggac
    15421 gcatggaacc gctcgtatcc acgacgaatc ccaggctcac cggggcttcg tcgcggctga
    15481 agtactcgat ttgctgctcc acctgttcat catagacacg gaagttttcc ttgcgcagat
    15541 cgccgacaaa gcggttgtcc tggtcgaaga cagccacatc gagaacaacc aggctggtat
    15601 ctatgttgaa cacctcgtcc tgggctgccg atggattggg tctttggggc cgcttgggcg
    15661 cacgctcctg cccgatcagg ccaagtgatg tgccttggag catggcaagg atgacaccag
    15721 tcaccagcca gagtttcgtt cctgtcattt tgtgactacc tcccggaatc ttgccttcag
    15781 tgggctgaac tccgtacgtt gcctgtggat ttttcttgtc gctgtgtttt ccgtgtgcta
    15841 ggttgagcgt ctgacaataa tgttttagca tctgcaaata actgcaaaaa aagactttag
    15901 ggattacgcc aaagatttcc acagggatgt ggggtatctg tggaaaacct gtggaaaact
    15961 tcttttccct atcgaaaacg gctcgtacct gccgcgcgtt gtgttgactg tcaagggttt
    16021 ggccatgatg gatgatgaca agtggacttc ttttctgggg gagatcgagc ggcgcatcaa
    16081 ccacgagagt ttcagcacgt ggttcaagcc ggtgacattg caggcctgcc agggtgacac
    16141 catctacctc cgggttccca accgaagcta tgaggactgg attacagaga cttaccacga
    16201 gtacgtcgaa gaagccctga aggcggttgg atgcagcggg gcgcgcctgg tgtttgttta
    16261 cacggagtcg cctgaaccca agtctgccaa cgggctgctt gacgatgatc atcccaagtc
    16321 aggcaaagat gccttttcct ttggtgtctt tgacagcgat ctctccgagg gtttggccgg
    16381 cacacgcatc gttgacctcg aaccgctcga actcccgctc aaccccaaat atacctttga
    16441 aaccttcgtc gtcggctcgt gcaatcagtt tgcacgcgcc gcagccatgg cggtggctga
    16501 cacgccaacc cgtacctaca atcccctgtt catctacggg ggcgtcggcc ttggcaagac
    16561 ccatctgatg catgccattg gccacgccat ccgcaaccgg gaccgccaca tgcggttggt
    16621 gtacatctcc tcggaaaagt tcatgaacga actcatcaac gccatccggt acgacaaagc
    16681 ccaggcattc cgcgagaagt accggagcat tgacgtgctg ttgattgacg acattcagtt
    16741 cattgccggc aaagaacgca cccaagaaga gttctttcac accttcaacg ccctctacga
    16801 cgcccagaag cagattgtca tttccagcga ctgcccgcca cgtgaaatcc ctacgctgga
    16861 agaacgcctc cactcccgtt ttgagtgggg actcattgct gaccttcagc cacctgacct
    16921 ggagaccaag gtcgccattc tgaaacgcaa ggctgatctg gagaaaattg acctcagcga
    16981 caatgtcgcg ctgttcatcg cgggaaaaat caagtccaac attcgtgaac tggaagggtc
    17041 gctcatccgg ctggtggctt acgcctcgct caggcaccgc ccgattgata tcgagctgtg
    17101 caaagaggtt ctcaacatcg aggaagaaga acggcccatc accatcgaga tgatccagcg
    17161 ggtggtcagc gaccactacg ggctacgggt ggctgacctc aaatccaaga acaactcccg
    17221 caacatcgcc gtgccacgcc aggtcgccat gtacctgtgc aagcagctca ccaaccacag
    17281 cctgcctgaa atcggacgcc actttggcaa caagcaccat acaaccgtgc ttcacagttg
    17341 tgagaagatt tcccgcctct accagaccca aaacgatttc cacaggctca tcaacaacct
    17401 aattagttca ttgaaataga cttagggcag ttttccacag atctgtggaa aactgcctgt
    17461 ggatgacctg tggaacctgt ggaaaactct gcccaccccc cgaagttttc cacaggttcc
    17521 acaggaaagg gctttttttc cacagctttt tccacagcca aattcaagcc taagtgttct
    17581 aaaatcaaca tcttgtaatt tttttccaca tttccacagg ccctactagg actactagat
    17641 catgatccat gtggatattt catgagttgt agtaaaaaga cgcccgcccg gaatcagcgg
    17701 tacgcagcgg ttcgggcagc ccgctcaagg caaatctggg ccttcaaacc gggaaagacc
    17761 gttgcccaaa tcggcagcac ctgctgggcg caccacactt ccaggctgat gtccgtgttg
    17821 tccacgggaa tgggcacaat ctgcaggctc tggtcctgca tctccacaat gacttccttg
    17881 actttgccgc cgtggcgacg gtcaagggca tcggcgaggc gcaggatggg aatcagcctg
    17941 gtgacggttt cctgatggac cggcagaagg cgggtgaagt cttcgtgctt gcgttttgga
    18001 agtgagccac ggtggtagcg cgccagattg gcaatgatgg ctatctcgtg tggatggaag
    18061 ccgggaagct cggcgtgacg aatgaggtac atcgcatgtt tgtgatggct tgtgtgtgcg
    18121 atgtggtagc caatatcgtg cagcagcgcc gcgcagcgaa gccattcccg ttcacgcatg
    18181 cccaatccgt ggaggggcag ggtctggtcg aaaatctgct cagcaagcct ggcggtgtgg
    18241 tgggcgtggc cggcttcgta ggcataccgg cgggcaacgg agagaatact gcgctcccgg
    18301 atgtccccgg ctgacagggg cgtatgggaa agcgaccagc cctgttcacg caggtagttg
    18361 atgacaactc cttcccgcag cgaccactca caggtggtca gatgctgaat acccagttcc
    18421 cggaagatgg tctccagcag gatgccgccg gcaacgatga tgtcagcccg gcgactgtcc
    18481 acaccgggaa gtttgcgtcg cgctttatgc ggcatccgtt gcagacggcg gttgagggct
    18541 tgcagctccg cgtaggtcag ttctgatgca aaggatgtaa atgcgacctt cttgggcgct
    18601 ggggcctttg tttccaggga gcgtgtatcg ggcttggcag cggcaagggc gaggatggtt
    18661 ccagaggttc cgacgacccg ctgaaaacct ccggcctcct ggatttcacg caccgtccgg
    18721 gcaaggccgc tctgaatgta ggtggtgagg gcttcaattt cagcgcgcga aggtgggtcc
    18781 tgccggctca gaaactgctc ctgaagacgg actgcgccca gcttgaccga ggccagatag
    18841 gctggcgtct ggccgtccgt cagaatgaac tcggtgcttc cgcccccgac atcaatgatg
    18901 agtccgcgtt caccctggaa atcggtaact tcagcgaccg ccaaggcaat gagccgggcc
    18961 tcttcgacgc cgggaagaat ctcaactttc agcccgattt cctgttcgac acgctggagg
    19021 aaaacctccc ggttccaggc ttcccggatg gcgctcgtcg ccaccaccag cacggctgtc
    19081 acgtcgtgcg cgtgcgccag gtcggtgaaa cgacggagcg tagcgacggc ggctttgatt
    19141 ttttcgtccg tcaggtggtg ggtttcggtg agaccagcgg ccaggcgtac ggtgtctttc
    19201 tcccgttcaa tgatacgcag tctttctccc ggacgggctt cagcaatgat gagatggatc
    19261 gagtttgagc caacatctat cgctgcgacg cggtgcagtg ctgaacccgg cctgggtgag
    19321 atgctttgac ggggagccgc aggcaatggt gagtcccggg aacgtagggt gatttcaggc
    19381 agagaccggt agggaagggc caactacgac aaccaacact ggcgaggcta gcaaaaattt
    19441 gactgcgcct caagtaaccg acacacccgg aagacagtgc gaaagtgggg gcaacgtcaa
    19501 tgaacttcgg tttggcactc ccgctgcagc catcctgctg ggaaggacgg cggggtggga
    19561 gacgccagcc caccactttc gccttacgga ggatattacc tgaatgtcgt ccccaagaca
    19621 cacctttgag cgacgattgg cttgctgttg ttttgcgcct cttatggcgc tggcctttgt
    19681 tcatcccact gccattgccc agtccaagtc accagcaaag ccggctgtca gtcagcccgc
    19741 tgtcacgcca gaggaaaaga cgcccaaaag cacaccggcg ctgacaaatg agcaacttca
    19801 ggccgacccc gaagccgccc tcaaggtact gctcgaaggc aatcgccgct ttgccgccgg
    19861 cgaaaccatc catccccgcc aggacattgc gcggattcgt gaaacggcca aagggcaaaa
    19921 accctttgcc atcatcatcg gctgctctga ttcccgggtg cccaacgaaa tcgtctttga
    19981 ccagggactg ggcgacctgt tcatcgttcg gaccgccggc caggtttcga cctattcttc
    20041 gtggggaagc atcgaatttg ccgaggaggt gcttggtgcc aagctcatct tcgtgctggg
    20101 gcacacgaaa tgcggcgcag tgcaggcggc tgtccgggtg ccggaggtgc cagggcacat
    20161 tgtcaccctc atcaacgaca tcaagcctgc tgcccagcgg gtcaagggcc agcccggcga
    20221 tgaagtcgaa aacgccgtcc gggaaaacgt ccgcacgcag gtcgaaaagc tcaaaaatct
    20281 tgagccggtt ctggccaagc ggtttcgtga gggcaagctc aagatcgtcg gcggcgtcta
    20341 tgacattgac accggtctca tcacgctcgt cgagtagtgc atccaccagg ctggcatagc
    20401 gctgctgtgc cagccgacca ccagctacac acccacgcac gagaggaaaa ccatgaacgc
    20461 tacccaagcg atgttcttga gcttgttgtc gccaatggtg ctcgctttca tccttggcgt
    20521 cattgccacc cgcgtcaaaa gcgacctgaa atttcccgaa gacctctaca cagcgctgac
    20581 gatttacctt ctcgtcgcca tcggtctcaa gggcggctac aagctttcca tcagtcatct
    20641 gagcgacttc tggcgaccgg gcctggcagc gattgcgctg ggagtcatta tcccgatagt
    20701 gagttattac atcctgcggc agctaggaaa gttcaacgtc tggaacgcgg cggccatcgc
    20761 agcccactat ggctcggtgt ccgctgtgac ctttggcgag gccattgcct tccacgacac
    20821 gctcaaggaa gaagccttgc gggccgccat cgaggccggt gctgttgctg ccgggacag
//
