LOCUS       NZ_CP073318            23224 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Kutzneria sp. CA-103260 chromosome, complete genome.
ACCESSION   NZ_CP073318
VERSION     NZ_CP073318.1
KEYWORDS    RefSeq.
SOURCE      Kutzneria sp. CA-103260
  ORGANISM  Kutzneria sp. CA-103260
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kutzneria.
REFERENCE   1  (bases 1 to 11609901)
  AUTHORS   Jorgensen,T.S., Gren,T., Kontou,E.E., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Complete Genome Sequence of the Rare Actinobacterium Kutzneria sp.
            Strain CA-103260
  JOURNAL   Microbiol Resour Announc 10 (30), e0049921 (2021)
   PUBMED   34323613
REFERENCE   2  (bases 1 to 11609901)
  AUTHORS   Joergensen,T.S., Gren,T., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2021) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-APR-2021
            Assembly Method :: Flye v. 2.8-b1674; unicycler_polish v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 87.0x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:18:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,326
            Genes (coding)                    :: 10,257
            CDSs (with protein)               :: 10,257
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 9 of 69
            Pseudo Genes (incomplete)         :: 63 of 69
            Pseudo Genes (internal stop)      :: 2 of 69
            Pseudo Genes (multiple problems)  :: 5 of 69
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:59:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8123389
            Orig. end                         :: 8146613
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP073318.1.
            Bacteria and source DNA available from Professor Tilmann Weber,
            Technical University of Denmark, Kemitorvet Building 220, room 327D
            2800 Kgs. Lyngby, Denmark.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23224
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="45"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23224
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23224
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13224](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13224)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(14..526)
                     /locus_tag="JJ691_RS35660"
                     /old_locus_tag="JJ691_71370"
     CDS             complement(14..526)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020418384.1"
                     /locus_tag="JJ691_RS35660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71370"
                     /product="DinB family protein"
                     /protein_id="WP_211763945.1"
                     /transl_table=11
                     /translation="MTTTEQTLTGEHAELLETLGKHRFFLRYTVQGLTDEQAALTPTAS
                     QLCLGGLIKHVTRAEKGWYDFAVGGPEAHPGTDVEGHLSSFRMLPGETLDGLLADYEAT
                     AQRTDALISSGVDLNQSWPLPVAPWFPPNASWSIRRVLMHVIAETAQHAGHADIIRETI
                     DGQKSMG"
     misc_feature    complement(548..562)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.21"
                     /tool="antismash"
     gene            complement(568..1803)
                     /locus_tag="JJ691_RS35665"
                     /old_locus_tag="JJ691_71380"
     CDS             complement(568..1803)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226160.1"
                     /locus_tag="JJ691_RS35665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71380"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_211763946.1"
                     /transl_table=11
                     /translation="MTKNILVSGASIAGPALAYWLREHGYTVTVVERAPAPRPGGYKID
                     VRGRAMEVLERMGLVDEVRRHHTDMRGGAFVDRRGRTVVEMDADTVGFREPTDVEILRG
                     DLARILLTATEGVEYVYGDSITALTEDERGVAVTFERSLPRRFDLVIGADGLHSAVRGL
                     AFGPEERFLRSLGHHIAIFSVPNLLELDRWETIQAEKGRTLNVYSTRQDTEAKAAFMFA
                     SPDVEYGRRDTARQQQILAEVFAPHGWIAPQLLDAMPAAPDFFFDDLSVVEMESWSTGR
                     VALVGDAAYGPSPASGQGTSLALVGAYVLAGELAAAGGDHKSAFAAYEQRMRHFVTLNQ
                     KQSSNIKRMVAGSRFTLWLNSTMMRLMPYLPGTSKIMDKVRAEIRDVSNAIDLPDYQNR
                     PESRTEAVRNPF"
     gene            complement(1828..4605)
                     /locus_tag="JJ691_RS35670"
                     /old_locus_tag="JJ691_71390"
     CDS             complement(1828..4605)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="JJ691_RS35670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71390"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_211763947.1"
                     /transl_table=11
                     /translation="MRIGVLGAVELWGPDGSPMALGGSRPRALLAALALNVGRPVSVDQ
                     LVDAVYGTEPPGNAHHALQSQVSRIRPLLPEGSLARHPAGYVLSLDSDEVDAHRFERLA
                     TEGRQLLALGDHANARKALVEALELWRGPAPTVRLDDLRLSAIEDRIETDLALGQPDVA
                     ELRQLAAENPYRERLRGQLMRALAADGRQAEALASFDDARRTLADEFGADPSAELAEAH
                     LAVLCGANPMRPVPAQLTSFVGRDKEIRQVSEALRAARLVTIIGPGGAGKTRLAIEFAR
                     RVAEVCFVELAELGDSAQVPQAVIGALGLRDGGLFGGGEAPDPVARLVAGLADRGILLV
                     LDNCEHVIDGAARLVRRLLAACAGLRILATSREALGITGESLCPLPPLAGPDTIRLFEE
                     RAHAVRPGYRLDPETVGQVCAAVDGLPLGIELAAARLRSFELDEVQARLRKLSHGDRTA
                     EPRHQTLRAVVAWSWDLLDDDERTMARRLSVFAGGATLSAAEEVCGRSADVLAGLVDKS
                     LVEVNAGRYRMLETVRAFCADQLDDESDRARRQHAEHFLRLAEEAEPCLRTGEQLTWMA
                     RLTAEHANLMSALRWAVGADPEIALRLAANTTWYLYLRGLRSDGIALVTELMTLLGKEV
                     PPGLDEEYLLCAVNVDVRVDRAAELLRRPGLQLRFPYLVMLWTMIGTAEEVTMEIFGDD
                     LWSRAFLRTAEGLRTLYHGELAVSRSCFEQACALFRDVGDRWGIANTVDQLAGIAALEG
                     DPAASLALIDEAIEVIGQLGDAEDAAELQCRRADNLVRLGEVAAARASYEQVAGLGLQP
                     TTASAHRGLGEIARLAGDLATARELHERALAECQAGPIVAAEIRSRILCGLGAIAAAQG
                     DADRAREHYERARDEALARQNLPMAAVAEQWLAGGALTWEQTLHRLRERFVSDW"
     gene            complement(4623..5228)
                     /locus_tag="JJ691_RS35675"
                     /old_locus_tag="JJ691_71400"
     CDS             complement(4623..5228)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF044515.1"
                     /locus_tag="JJ691_RS35675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71400"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_211763948.1"
                     /transl_table=11
                     /translation="MPPSIAGSTRAELARLIHPPLRADARRNYEAVLAAAAEVFAAGGP
                     DASLDEIARRAGVGNATLYRHFPHRRDLLVAVCVDEVEKLCVIGEKLRGSSTDALESWL
                     HAYIHHVRTRNGLAAAFVAGDSEDSVFVAACRAAVGEVATALLQDAQQAGVIRGDLRLD
                     DLLTLANAIAMVTESSDRSHAENLLTLVVEGFRPRSAS"
     gene            5324..5680
                     /locus_tag="JJ691_RS35680"
                     /old_locus_tag="JJ691_71410"
     CDS             5324..5680
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018777.4"
                     /locus_tag="JJ691_RS35680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71410"
                     /product="EthD domain-containing protein"
                     /protein_id="WP_211763949.1"
                     /transl_table=11
                     /translation="MYKKLSFLRKRAGMATEDFIDYYENHHVPLILSLAPTPDVYKRHY
                     VVWGDTLNIREDELDFDVMSEIAFPDRAAFDAWLAALGAAGTRVPDDEARFLDRSYLRS
                     FANDERVTSENVLS"
     gene            5774..6001
                     /locus_tag="JJ691_RS35685"
                     /old_locus_tag="JJ691_71420"
     CDS             5774..6001
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020034.4"
                     /locus_tag="JJ691_RS35685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71420"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_211771910.1"
                     /transl_table=11
                     /translation="MYVDPEHRGHGLGPRLLVALIEQLPTDADRLWIEHFAANERAGAF
                     YERQGYAVERIEPSPDGDPARSVVWRARRL"
     gene            complement(6020..8968)
                     /locus_tag="JJ691_RS35690"
                     /old_locus_tag="JJ691_71430"
     CDS             complement(6020..8968)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="JJ691_RS35690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71430"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_211763950.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.6e-23, bitscore:
                     82.0, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRYRLLTAATTLSMSAALALLGNGVAAAAPVPLAPAVDGAADGG
                     RVIVVLANQHGDLKLRAQSSQRTATTHTDQQSVVSDIKANGGTDVTQLVSVNAVAAHLS
                     AAEVNRLRANPAVQQIVPDEPMPVDTPAQTPKAPAAKLSQKLCPTDPTHPLLEPEALSV
                     DKVETDRPGDVEQASKIATGKGVLVAIDGMNQLAGNPNFVRPDGSHVVIDAPNPNEDDS
                     DGEYYGDASSVAGQGLVTYDFSKELPYSGLPAGCTFRIKGVAPDASLVDSSLIDTPPSA
                     SGQVHYESQVVAGIDHAVVTEHADVISESYGYTPRPGRYSVFYAANDAAVAAGVTVVVS
                     SGDSGVSGTVSSPATDPQVIAVGATNTLRLTSQAYGYDSWINNDITPLSSGGTAPNNRV
                     VDLVAPGYGGEAACSPTGSDCPTNTLTEAFGGTSESCPLVAGAVADVIQAYADTHHGVK
                     PTPALIKQILTGTAQDVGAPADQQGAGLLNVYAAVRAAQQEPGSTLVSDAPALVPSPSQ
                     LDITANAGVSAQTVNLYNAGALPTTVTGTYRELGAAKQIGATVTEPVSAPDPSLPVPAA
                     GATAASPITFDVPKGLDRLNADMIIPDPANGTILSFTLVDPKGRLSQISYDYGTAPTGS
                     AKFGTVSNIQHVEVAAPTAGTWTAKILWANGRAHLQSPPNVPGSYRGDISFRATGQHYV
                     TTPATGPVTIPAHGSADVALNVAMPTAPGDHPESVQFVAANGATTSLPVARRTLVPSAG
                     GSFTTDITSSVGRQVGQISTLNIDVPAGKKDLDVSFHTADASADNGIAYYLIDPDGKVV
                     TTDATPATTVQGIGSDKPVGDAALVTANPKPGRWEIDVMLKLTESGKEFTQQVHGTVGY
                     NRSDAVAYNLPAVGSKVAAQSSTALYFRVANTTGVGRTFRLSPTGSDITAGTPVYLPAG
                     TSALLTATLKPTAAAGTAVTGTVNVLSNTSAGGAQTFASLPYGYTVGTAVSP"
     misc_feature    complement(8789..8791)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9079..10011)
                     /locus_tag="JJ691_RS35695"
                     /old_locus_tag="JJ691_71440"
     CDS             complement(9079..10011)
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010311801.1"
                     /locus_tag="JJ691_RS35695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71440"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_211763951.1"
                     /transl_table=11
                     /translation="MTTERTVLLASPRSFCAGVDRAIEIVEQLLARRGGPIYVRKQTVH
                     NTHVVADLSGRGAVFVDELTEVPAGATVVFSAHGVSPAVRSEAVDRGLDVVDATCPLVT
                     KVHSEARRFAARGDTVVFIGHAGHEEVEGTLGEAPDRMVLVETAEDVATLEVEDPSRVS
                     YLTQTTLAVDETTAVVDALRARFPALRGPGSDDICYATTNRQRSLAAVADEADLVLVVG
                     SANSSNSVRLVEVARRMGTPAYLVDDISGISESWLAGVRVVGLTAGASAPPELVDEVVQ
                     WLRRFGPVRVEERETARETITFGLPSAAR"
     gene            complement(10001..11053)
                     /locus_tag="JJ691_RS35700"
                     /old_locus_tag="JJ691_71450"
     CDS             complement(10001..11053)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103444.1"
                     /locus_tag="JJ691_RS35700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71450"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_249227222.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.7e-58, bitscore:
                     194.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEGVIPIDVISQPRSAREVLAWSRGVVDPAMRAAVDTLPTSMRR
                     VAGYHYGWWDADGTPRDGDAGKAIRPALAALCAEAVGGSIVDAVPAAVAVEMVHNFSLL
                     HDDVMDRDVSRRHRPTAWTVFGISSAILAGDALLTLAFDVLAGSGHARAQDAMRMISSA
                     VQDLVEGQCEDVSFEERSDVDLSECLSMAGEKTGALLACSTAIGALYGGGTAEQVEHMR
                     VFGEHLGLAFQLVDDLLGIWGDPRVTGKSAHSDLVSRKKSLPVVAALTSGLPAADELAA
                     LYGRQDELSEVELARAAELVELAGGRSWAQREAVDQLDLALAELAQGAPVARAAAELDT
                     LARMVTRRDH"
     gene            complement(11050..13224)
                     /locus_tag="JJ691_RS35705"
                     /old_locus_tag="JJ691_71460"
     CDS             complement(11050..13224)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010311476.1"
                     /locus_tag="JJ691_RS35705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71460"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_211763952.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-77, bitscore: 261.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFELPEFYLVHPARLNPNLEGARVHTRQWARDFDMIDTPAFE
                     GGEIIWSPAKLEAMDYALLCAYTHPECSGEILNLITDWYVWVFFFDDHFLELYKKPKDI
                     KGAKKYLDGLREFMPLHGAITATPTNPVEAGLTDLWERTIPMMSQEWKVRFIESTLNLL
                     VECMWEIINIDEGRVANPIDYIEMRRKVGGAPWSANLVEVAVGAEVPDSVARTRPLRVL
                     RDTFADGVHLRNDVFSYQREVEEEGENANMVLVLETALGCTAQEAAEATNDLISSRMQQ
                     FEHTVFTELPILFDEYHLRPDERMAVLVYARGLQDWQSGGHEWHMRSSRYMNSNADKAG
                     WVPGGPTGLGTLGARFGIPKRFNRFTHTPHAVGPTSLPEFTMPFTLRVNPLLDNARRHT
                     TEWARTMGMTTEGVWTDRQLAGFDFARCCAGLHPDAGQDELDLATEWTIWGTYADDLFP
                     MLFFHTRDVVGPRAFVARSLEFAPLDCATMPSPANAYERGLADLWLRTALPLADQHRAQ
                     FRRSLERLFESWLWEADHHQQNRIPDPVDYIEMRRETWGSLPTMSLAGFGRAELIPAEF
                     FATSQLRGLECSAMDQACFVNDVFSYQKEIEFDGELMNMVLVVENFLGCGKDQAVAIVN
                     DLATARIEQFVRTRDHEIPTLCEEFGFTAEQRRAVDGYVRELEDWMAAILDWHRTTARY
                     GSAELVRSRGGRGFALPTGFGTSAVRMFAS"
     misc_feature    13208..13223
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.73"
                     /tool="antismash"
     gene            complement(13237..14628)
                     /locus_tag="JJ691_RS35710"
                     /old_locus_tag="JJ691_71470"
     CDS             complement(13237..14628)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004561479.1"
                     /locus_tag="JJ691_RS35710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71470"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_249227223.1"
                     /transl_table=11
                     /translation="MTETLDPASTQLSLGTAAARQLATTTKSVPQMQAITPRWLLHMLP
                     WAEAKGAVYRVNRRLTFPVGSGRVAFTNTGSAVRIIPETLTELPLYRGFEDTAVLHAIA
                     DRLVQREFSAGETIVAAGDPSEAGFLIAYGRAEMVGTGKYGDETRLGNLAEGEYFGQQM
                     MEESPGPWEYTVRAATRCIVLTMSRDQLGPLLAGSESLRAHVERLRAGTALAQNKHGEA
                     AIELASGGSGEYTVPGTFVDYDLSPRQYELAVGQTMLRIHTRVADLYNGPHDQVQEQLR
                     LTIAALRERQEFDMLNNPEFGLLHNVDLKQRVLPRSGPPTPDDMDELVSRRRKTKFFLA
                     HPKAIAAFGRELTARRIYPAPVVVDGKAMLSWRGVPILPCDKIPIDPDTNTTSILAMRT
                     GEDDNGVIGLHQTGIPDEREPGLSVRFTGINEKAIMSYLVSTYYSCAVLVPDALGVLED
                     VELGN"
     gene            complement(14804..16219)
                     /locus_tag="JJ691_RS35715"
                     /old_locus_tag="JJ691_71480"
     CDS             complement(14804..16219)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225101.1"
                     /locus_tag="JJ691_RS35715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71480"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_211763953.1"
                     /transl_table=11
                     /translation="MTETLEPGAGVEQGQSQLSLGTAAARNLSTTTKSVPQMQGITSRW
                     LMRVLPWIQVNGGVYRVNRRLSYTVGDGRIEFTNVGADVRVIPAELGELPLLRGFDEMD
                     VLEAMAGRFSQHEYSAGDVIAEAGSAADRVYLIAHGKINKIGAGKYGDESALGTLADGE
                     FFGADALVDPDANWDFTARAVTSATVLSLSRADFQALCDQSAALREQIVLFQANAALGR
                     DDSGEAAINVASGHTGEPDLPGTFVDYDAAPREYELSVAQTVLRVHSRVADLYNQPMNQ
                     TEQQLRLTIEALRERQEHELVNSRDFGLLHNADFSQRIHTRGGAPTPDDMDELLATVWK
                     APTVFLAHPRAIAAFGQECTRAGIYPGNVDFNGHQVPAWRGVPILPCNKIPITEQRTSS
                     IILMRAGDEHTQGVVGLHQTGLPDEYQPGLSVRFMNISEKAIISYLVSAYYSCAVMVPD
                     ALGILEDVQLGAN"
     misc_feature    16302..16316
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.71"
                     /tool="antismash"
     misc_feature    16423..16438
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.57"
                     /tool="antismash"
     gene            17048..17683
                     /locus_tag="JJ691_RS35720"
                     /old_locus_tag="JJ691_71490"
     CDS             17048..17683
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="JJ691_RS35720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71490"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_211763954.1"
                     /transl_table=11
                     /translation="MRDGGGTGRRLMPRPERAASIVAAAARAFARGGYAGTSMDDVAAE
                     AGVTKIILYRHHKTKKDIYTAALDTTWQRLVDSSQLGYDTEAGLRGLLAAARRDAAGFT
                     LLFRHAVREPEFAEYAQQLVAQTVQVAEETLADSVRDPRLRAWLARGVTDLVLNSVLEW
                     ITTGDPDRDDEAAGLLFQTAAAVIVHHRSRAVPHPSTRRSDGLRETVY"
     gene            17739..18098
                     /locus_tag="JJ691_RS35725"
                     /old_locus_tag="JJ691_71500"
     CDS             17739..18098
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="JJ691_RS35725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71500"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_211763955.1"
                     /transl_table=11
                     /translation="MATGQFPADDAETAANVFAGELKRWRTLRGLSRTTLARRMGYDRS
                     YVSKVESGAKPPSRDFAFHAEKALHSGGALYNAYREHSSSVERSKADGQLVRAASRPTQ
                     PYADLIVGGVPPAGR"
     gene            complement(18241..18999)
                     /locus_tag="JJ691_RS35730"
                     /old_locus_tag="JJ691_71510"
     CDS             complement(18241..18999)
                     /NRPS_PKS="Domain: Thioesterase (19-233). E-value: 3.4e-40.
                     Score: 130.8. Matches aSDomain:
                     nrpspksdomains_JJ691_RS35730_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="JJ691_RS35730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71510"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_211763956.1"
                     /sec_met_domain="Thioesterase (E-value: 1.9e-39, bitscore:
                     135.4, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.9e-09, bitscore:
                     36.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTGAKILVRPRPRPQASRVLMCIGYSGGGTAPFRRWVQQLPDDV
                     ELVLVCYPGREGRFTEPYATQWEQLCEEVVDAVVTEVATRPYQLFGHSMGAVMAFEVAA
                     RAERRGRGPAVLTVSASEAPTDWPRDDGEPPHISQTDAELLHWMSTVGQLPQELLSEPG
                     LVQMAVSLLRADLMVSHSYRYRPGTVVSAPMQVIFGAEDGKSPAANAQRWTKLAAGPVR
                     VEELPGGHFYTPEIWAAFPSRIASPGSFTG"
     aSDomain        complement(18301..18942)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JJ691_RS35730_Thioesterase.1"
                     /evalue="3.40E-40"
                     /label="JJ691_RS35730_Thioesterase.1"
                     /locus_tag="JJ691_RS35730"
                     /protein_end="233"
                     /protein_start="19"
                     /score="130.8"
                     /tool="antismash"
                     /translation="VLMCIGYSGGGTAPFRRWVQQLPDDVELVLVCYPGREGRFTEPYA
                     TQWEQLCEEVVDAVVTEVATRPYQLFGHSMGAVMAFEVAARAERRGRGPAVLTVSASEA
                     PTDWPRDDGEPPHISQTDAELLHWMSTVGQLPQELLSEPGLVQMAVSLLRADLMVSHSY
                     RYRPGTVVSAPMQVIFGAEDGKSPAANAQRWTKLAAGPVRVEELPGGHFYT"
     CDS_motif       complement(18685..18750)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JJ691_RS35730_0001"
                     /evalue="8.90E-10"
                     /label="NRPS-te1"
                     /locus_tag="JJ691_RS35730"
                     /protein_end="105"
                     /protein_start="83"
                     /score="31.0"
                     /tool="antismash"
                     /translation="TRPYQLFGHSMGAVMAFEVAAR"
     gene            19035..19676
                     /locus_tag="JJ691_RS35735"
                     /old_locus_tag="JJ691_71520"
     CDS             19035..19676
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013718.4"
                     /locus_tag="JJ691_RS35735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71520"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_211763957.1"
                     /transl_table=11
                     /translation="MRLLPPQARRSAVGLVVLSVVVVAVGAALYHGQQRAGRLDDAVDD
                     WLFTVFGQHRVFLYQLLHVADLPVVIAVLVVVLVAALMRGRPDIAALAAIGPLASIGLT
                     EAVLKPLVHRRYNFFLSYPSGHTVGTASECAVLGVILLGATGLTLALRVAMGVLLLVVC
                     ATVMLALIVDDFHYFTDTVAGASLSVGVVALTALAVDAVTRRRVLAAAPV"
     gene            19792..21255
                     /locus_tag="JJ691_RS35740"
                     /old_locus_tag="JJ691_71530"
     CDS             19792..21255
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016698850.1"
                     /locus_tag="JJ691_RS35740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71530"
                     /product="family 10 glycosylhydrolase"
                     /protein_id="WP_249227224.1"
                     /transl_table=11
                     /translation="MRRLATTVAALLIVVMALPAAAATTDSVSGTSVSGTRELRGMWIA
                     SVANIDWPAKPGLPVAQQEQEYESLLDRAKATGVNAVFVQIRPTADSFYPSSLEPWSQY
                     LTGTQGQDPGYDPLKFLVSQAHQRDLEFHAWFNPYRISLQSDVTKLAPNHPARLHPDWV
                     VSYGGQLYYNPGIPAVRRFVEKVILDTTRRYDIDGVHFDDYFYPYPVAGQQFPDQQTFQ
                     QYSGGFTNVTDWRRDNVNKLISELSTRIHSMKPWIAFGVSPFGIWRDARTDPTGSDTQG
                     GVHDYDDLYADTRTWIRNRWVDYIAPQLYWPVGYTIADYGKLLPWWAHEVAGTGVSLYI
                     GQAVYKIGTPSPAAWLDPEEMPRHIALDRGTPEVNGDILYNTTTLLANPLGFADRLRTD
                     LYAKPAIVPVRPTVAGHAPPSPILLPLFGNTLHWLGFGTSYAVYQDGRLLTTVRGTSFA
                     LPAGRHRYAVTALDRTHHESRPSGTEEYR"
     gene            21252..22538
                     /locus_tag="JJ691_RS35745"
                     /old_locus_tag="JJ691_71540"
     CDS             21252..22538
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009083764.1"
                     /locus_tag="JJ691_RS35745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_71540"
                     /product="C39 family peptidase"
                     /protein_id="WP_249227225.1"
                     /transl_table=11
                     /translation="MSPVHNRLTRLAMVGTVAGALIAQLTAAPAVAATAAAPVDFHQWN
                     SDSQFHSGHSDGLLVGNGLTIGRPAGTVQHTEPDLGTTKAYDYGTWTSPRYSQRFGATQ
                     LVASWNATTPAGTFLQVEMRGTASTGTQTGWYVMGRWASSDEDIHRTSVPDQTDATGTI
                     DVDTFEAAQGVQLMSYQLRVTLYRLHGTRVSPHLRMVGAMTSAIPDRFSVPTSPSGGAW
                     GIELPVPRYSQDIHEGEYPQYDGGGEAWCSPTSTEMVVEYWGKHPTAQQLSWVDPSYAD
                     PSVDYAARNTYDYDYQGAGNWPFNAAYAASYGLDAHITRLHSLQELEKYIKRGIPVITS
                     QSFQASELDGAGYSTSGHIMVVVGFTKTGDVIVNDPASHDDAAVRNVYKRSQFENVWQR
                     TERPLPGGGTGTGSGGVVYIVTPHGMPLP"
ORIGIN
        1 cggaagcagc aggtcagccc atggacttct ggccgtcgat ggtctcgcgg atgatgtcgg
       61 cgtggccggc gtgctgggcg gtctcggcga tgacgtgcat cagaacgcgg cggatggacc
      121 agctggcgtt gggcgggaac cagggggcga cgggcagcgg ccagctctgg ttgaggtcga
      181 cgccggagga gatgagggcg tcggtgcgct gggcggtggc ctcgtagtcg gcgagcaggc
      241 cgtcgagggt ttcgccgggc agcatgcgga agctggagag gtggccctcg acgtcggtgc
      301 cagggtgggc ctcggggccg cccacggcga agtcgtacca gcccttctcg gcccgggtga
      361 cgtgcttgat gaggccgccg aggcagagct ggctggcggt gggggtgagc gcggcctgct
      421 cgtcggtgag gccctggacg gtgtagcgga ggaagaaacg gtgcttgccc agggtctcca
      481 gcagctcggc gtgctcgccg gtcagcgtct gctcggtggt ggtcatcgtg ggcccctctc
      541 gtggtgtttt ccctgttgag aaccacacta gaagggattg cggacagctt ctgtcctcga
      601 ttccggacgg ttttggtagt ccggtagatc gatggcgttg gagacgtcgc ggatctcggc
      661 ccggaccttg tccatgatct tggaggtgcc gggcaggtag ggcatcaggc gcatcatcgt
      721 gctgttgagc cagagggtga accgcgaacc ggccaccatg cgcttgatgt tgctggactg
      781 cttctggttg agggtgacga agtgccgcat tcgttgctcg tacgccgcga aggcggactt
      841 gtggtcaccg ccggcggcgg cgagttcacc ggccagcacg taggcgccga cgagggcgag
      901 gctggtgccc tggccggacg cgggcgacgg gccgtaggcg gcgtctccga ccagcgcgac
      961 ccggccggtg gaccaggact ccatctcgac aacgctcagg tcgtcgaaga agaagtcggg
     1021 cgcggcgggc atggcgtcga gcagctgggg cgcgatccag ccgtgcgggg cgaagacctc
     1081 ggccaggatc tgctgctggc gggcggtgtc ccgccgcccg tactcgacgt ccggcgaggc
     1141 gaacatgaag gcggccttgg cttcggtgtc ctgccgggtg ctgtagacgt tgagggtccg
     1201 ccccttctcg gcctggatgg tctcccagcg gtccagctcc agcaggttgg gcacgctgaa
     1261 gatggcgatg tggtggccga gggagcgcag gaagcgctcc tccggcccga aggccagacc
     1321 ccggacggcg gagtgcaggc cgtcggcgcc gatcacgagg tcgaaccgcc gtggcaggga
     1381 ccgttcgaag gtgacggcga cgccgcgctc gtcctcggtc agtgcggtga tcgagtcgcc
     1441 gtagacgtat tcgacgccct cggtggcggt gagcaggatg cgagccaggt cgccgcgcag
     1501 gatctcgacg tcggtgggct cgcggaaacc gactgtgtcg gcgtccatct ccacgacggt
     1561 gcggccgcgg cggtcgacga acgcaccgcc acgcatgtcg gtgtggtgcc ggcgaacctc
     1621 gtccacgagg cccatgcgct ccagcacctc catggcccga ccgcgcacgt cgatcttgta
     1681 gccgccgggg cggggcgcgg gtgcgcgctc cacgacggtg acggtgtagc cgtgttcacg
     1741 cagccagtag gcgagggccg ggccggcgat gctggccccg gagaccagga tgttcttcgt
     1801 catgccgcag actctgcggc ggccggttca ccagtcgctc acgaagcgct cacggagccg
     1861 gtgaagcgtc tgctcccagg tgagcgcgcc gccggccagc cactgctcgg cgacggccgc
     1921 catgggcagg ttctgcctgg ccagggcctc gtcacgggcc cgctcgtagt gctcacgggc
     1981 ccggtcggca tcgccctgcg cggcggcgat cgcgcccagc ccgcacagga tccgggagcg
     2041 gatctcggcg gcaacgatcg gcccggcctg gcattcggcg agcgcccgct cgtgcagctc
     2101 acgggcagtg gccaggtcgc cggccagccg ggcgatctca ccgagacccc ggtgcgcgga
     2161 ggctgtcgtc ggctggagac cgagacccgc cacctgctcg tagctggccc gcgcggcggc
     2221 gacctcgccg agccgcacga ggttgtcggc ccggcggcac tgcaactcgg ccgcgtcctc
     2281 ggcgtcaccg agctggccga tcacctcgat cgcctcgtcg atcagcgcca gcgacgcggc
     2341 cggatctcct tccagcgcgg cgattccggc gagctggtcg accgtgttgg cgatgcccca
     2401 ccggtccccc acgtcccgga acaacgcgca cgcctgctcg aaacaggacc gggagacggc
     2461 cagctcgccg tggtagaggg tccgcaggcc ttcggccgtc cgcaagaacg cgcgtgacca
     2521 caggtcgtcg ccgaagatct ccatggtgac ctcttcggcg gtgccgatca tcgtccacaa
     2581 catcaccagg tacgggaagc gcagctgcaa tcccggccgc cgtagcagct ccgcggcccg
     2641 gtcgacgcgc acgtcgacat tgaccgcaca gagcaggtac tcctcgtcga ggccgggcgg
     2701 gacttccttg cccagcaacg tcatcagctc ggtcacgagg gcgatgccgt cactgcgcag
     2761 gccgcggaga tagaggtacc acgtcgtgtt ggcggccagt cggagcgcga tctccgggtc
     2821 cgcgccgacc gcccaccgca gggccgacat gaggttggcg tgctcggcgg tcagccgggc
     2881 catccaggtc aactgctcgc cagtacgcag acacggctcg gcctcctcgg cgagccggag
     2941 gaagtgctcg gcgtgctggc ggcgagcccg gtcgctctcg tcgtcgagct ggtcggcgca
     3001 gaacgcgcgg acggtctcca gcatccggta gcggccggca ttgacctcga ccaacgactt
     3061 gtcgaccagg ccggcgagca cgtccgcaga ccggccgcag acctcctcgg cggcggaaag
     3121 cgttgccccg ccggcgaaaa ccgacagccg ccgggccatg gtgcgctcgt cgtcgtcgag
     3181 caggtcccaa ctccaggcga ccaccgcacg cagcgtctgg tgccggggct cggcggtgcg
     3241 gtcgccgtgc gagagcttcc gcagccgggc ctgcacctcg tccagctcga acgaccgcag
     3301 ccgggccgcc gcgagttcga tgcccagcgg cagcccgtcg accgccgcgc agacctggcc
     3361 gacggtctcg gggtcgagcc ggtagcccgg gcggaccgcg tgggcgcgct cctcgaacag
     3421 gcggatcgtg tccgggccgg ccagtggcgg cagcgggcag agcgattccc cagtgatgcc
     3481 aagggcttca cgactggtcg ccaggatccg cagccccgcg caggcggcca acagccgtcg
     3541 gaccagccgg gccgcgccgt cgatgacgtg ctcgcagttg tccaggacca gcaggatgcc
     3601 ccggtcggcg aggccggcga ccaggcgggc caccggatcc ggggcctcgc cgccgccgaa
     3661 cagcccgccg tcacgcagcc ccaacgcgcc gatcaccgcc tgcggcacct gggccgaatc
     3721 gccgagctcg gccagctcga cgaaacacac ctcagccacc cgacgggcga actcgatggc
     3781 caggcgggtc ttgcccgcgc cgccggggcc gatgatcgtc accagccgcg cggcccgcag
     3841 cgcctcgctg acctggcgga tttccttgtc ccgcccgaca aagctggtca actgggccgg
     3901 cacgggacgc atcgggttgg caccgcacag cacggccagg tgagcctcag ccagctcggc
     3961 tgacgggtcg gcgccgaact cgtcggccag ggttcggcgg gcgtcatcga agctggccag
     4021 cgcctcggcc tggcggccat ccgccgccaa cgcccgcatg agctggccac gaagtcgttc
     4081 gcggtacggg ttttccgctg ccagctggcg aagttcggcg acgtcgggct ggccgagggc
     4141 caggtcggtc tcgatgcggt cctcgatcgc cgacagtcgc aggtcgtcga ggcggacggt
     4201 cggggccggg ccacgccaca attccagggc ctcgaccaaa gccttgcggg cattggcgtg
     4261 gtcgcccagg gcgagcagtt gccggccctc ggtcgccagg cgctcgaagc gatgcgcgtc
     4321 aacctcgtcg gaatcgaggc tcaggacgta gccggccgga tgccgtgcca ggctgccctc
     4381 aggcagcagg ggccggatcc tggacacctg cgactgcaag gcatggtggg catttccggg
     4441 cggctccgtg ccgtagacgg cgtcgaccag ctggtcgacg gacaccggcc ggccgacgtt
     4501 cagcgccagc gcggccagca gggcccgcgg ccgggaaccg ccgagggcca tcgggctccc
     4561 gtcgggcccc cacagctcga ccgcgccgag cacaccgatc cgcacccgga cattctgctt
     4621 gctcaggacg ccgatcgagg ccggaatccc tcaaccacca gcgtcagcag gttctcggcg
     4681 tggctgcggt cgctcgactc ggtgaccatg gcgatggcgt tggccagggt caacaggtcg
     4741 tcgagccgaa ggtcgccccg gatgacgccg gcctgctgcg cgtcctggag cagggcggtg
     4801 gccacctctc cgaccgcggc ccgacaggcc gcgacgaaca cggagtcctc gctgtcgccg
     4861 gcgacgaacg cggcggccag gccgtttcgg gttcggacgt ggtggatgta ggcgtgcagc
     4921 cacgactcca gcgcgtcggt cgagctgccc cgcagctttt ccccgatgac acagagcttt
     4981 tcgacctcgt cgacgcacac cgcgacgagc aggtcgcgtc ggtgcgggaa atggcggtac
     5041 agggtcgcgt tgcccacgcc cgcccgacgg gcgatctcgt ccagcgaggc gtccggaccg
     5101 ccggcggcga agacctcagc cgcggcggcc agcacggcct cgtaattgcg ccgcgcgtcc
     5161 gcccgcagcg gcgggtggat cagccgggcc aactcggccc gggtcgagcc ggcgatcgac
     5221 ggcggcacgg cggcctcctt gccaactggg gagttcccca cttacggtac tacacagcaa
     5281 ccggggaact ccccagttat cgccgacaag gaggccgcac ccgatgtaca agaagctctc
     5341 gttcctcagg aagcgggccg gcatggccac cgaggacttc atcgactact acgagaacca
     5401 ccacgtcccg ctgatcctca gcctcgcgcc gaccccggac gtctacaagc ggcactacgt
     5461 ggtgtggggc gacaccctca acatccggga ggacgagctc gacttcgacg tgatgtcgga
     5521 gatcgccttc ccggaccgcg cggccttcga cgcctggctc gccgcgctgg gcgccgccgg
     5581 cacccgcgtc cccgacgacg aggcgaggtt cctcgaccgc tcctacctcc ggtccttcgc
     5641 caacgacgaa cgcgtgacct cggaaaacgt tttgtcgtag cgtggacggg agaggcaacg
     5701 atgctggttg tgcggaatgc cgggctcgac gacgtcgcac ccgtccgccg gttcggcgag
     5761 agagtgattc cgcctgtacg tcgaccccga acatcgcggt cacggactgg gtccgcgact
     5821 gctggtggcc ctcatcgagc agctgccgac cgacgcggat cggctgtgga tcgagcattt
     5881 cgcggccaac gagcgggccg gggcgttcta cgagcggcag ggctacgcgg tggaacggat
     5941 cgagccgagt cccgacgggg acccggctcg atcggtggtg tggcgggcgc gccggttgtg
     6001 accgacgcgc cgatcacggt caggggctga cggcggtgcc cacggtgtag ccgtacggca
     6061 gggacgcgaa ggtctgcgcc ccgccggcgc tggtgttgct gaggacgttg accgtgccgg
     6121 tgacggcggt gcccgcggcg gcggtcggct tcagcgttgc ggtgagcagc gcggaagtgc
     6181 cggcgggcag gtagaccggg gtgccagcgg tgatgtcgga gccggtgggg ctgagccgga
     6241 aggtgcgacc gacgccggtg gtgttggcga cccggaagta caacgcggtg ctcgactggg
     6301 cggcgacctt gctgcccacg gccggcaggt tgtaggcgac ggcgtcggat cggttgtagc
     6361 cgacggtgcc gtgcacctgc tgcgtgaact ccttgccgct ctcggtcagc ttgagcatga
     6421 cgtcgatctc ccaccgcccg ggcttggggt tggcggtgac gagcgcggcg tcgccgacgg
     6481 gcttgtccga gccgatgccc tgcacggtgg tggccggcgt ggcgtcggtg gtgacgacct
     6541 tgccgtcggg gtcgatcagg tagtacgcga tgccgttgtc ggcactggca tccgcggtgt
     6601 ggaagctgac gtccaggtcc ttcttgccgg ccggcacgtc gatgttgagc gtgctgatct
     6661 ggccgacctg ccggccgacg gagctggtga tgtccgtggt gaacgagccg ccggccgacg
     6721 gcaccagggt gcggcgggcc accggcagcg acgtggtggc accgttggcg gccacgaact
     6781 gcaccgactc ggggtggtca ccgggagccg tcggcatggc cacattcagg gccacatcag
     6841 cggatccgtg cgcggggatg gtcaccggac cggtcgccgg cgtggtgacg tagtgctggc
     6901 cggtggcccg gaacgagatg tcgccgcggt aggagcccgg cacgttcggc ggggactgga
     6961 gatgcgcccg gccattggcc cacaggatct tcgcggtcca ggtgccggcg gtcggggcgg
     7021 ccacctcgac gtgctggatg ttggagacgg tgccgaactt ggcgctgccc gttggggcgg
     7081 tgccgtagtc gtaggagatc tggctcagcc ggcccttggg gtcgaccagg gtgaacgaga
     7141 gaatggtgcc gttggcggga tccgggatga tcatgtcggc gttgagccgg tcgagtccct
     7201 tgggcacgtc gaaggtgatc ggcgaggcgg cggtggcccc ggccgccggc acgggcaggc
     7261 tcgggtccgg cgcgctgacc ggctcggtga cggtggcgcc gatctgcttg gccgcaccca
     7321 gttcccggta cgtcccggtg acggtggtcg gcagcgcgcc ggcgttgtag aggttcacgg
     7381 tctgcgcgct gacaccggcg ttggcggtga tgtccagttg ggacggtgac ggcacgaggg
     7441 ccggggcgtc ggaaaccagg gtgctgcccg gttcctgttg ggcggcccgc accgcggcgt
     7501 acacgttgag caggccggcg ccctgctggt cggcgggcgc gccgacgtcc tgggcggtgc
     7561 cggtgaggat ctgcttgatc agcgccgggg tcggcttcac gccgtggtgg gtgtcggcgt
     7621 aggcctggat gacgtcggcg accgcgccgg ccaccagcgg gcacgactcg ctggtgccgc
     7681 cgaaggcctc ggtcagggtg ttggtcgggc agtccgaacc ggtcgggctg cacgccgcct
     7741 cgccgccgta gccgggcgcg accaggtcca cgacccggtt gttgggcgcg gtgccgccgg
     7801 aggacagcgg cgtgatgtcg ttgttgatcc aggagtcgta gccgtaggcc tggctggtca
     7861 ggcgcagcgt gttggtcgcg cctacggcga tcacctgcgg gtcggtggcc ggcgaggaca
     7921 ccgtgccgga gacgccgctg tcaccggagg agacgaccac tgtgacaccg gccgcgaccg
     7981 cggcgtcgtt ggccgcgtag aacaccgaat agcggccggg gcgcggggtg tagccgtagg
     8041 actcggagat cacgtcggcg tgctcggtca ccaccgcgtg gtcgatgccg gcgacgacct
     8101 gcgactcgta gtggacctgg cccgaggcgc tgggcggggt gtcgatcagc gaggagtcga
     8161 ccagcgacgc gtccggggcg acgcccttga tgcggaaggt gcagccggcc ggcaggcccg
     8221 agtagggcag ctccttgctg aagtcgtagg tgaccagacc ctggccggcc accgaggaag
     8281 cgtcgccgta gtactcgccg tcgctgtcgt cctcgttcgg gttcggcgcg tcgatgacca
     8341 cgtgcgagcc gtccggccgg acgaagttcg ggttgccggc caactggttc atgccgtcga
     8401 tggcgaccag cacgcccttg ccggtggcga tcttcgaggc ctgctcgaca tcgccgggcc
     8461 ggtcggtctc gaccttgtcg accgacaggg cctccggctc cagcagcggg tgcgtggggt
     8521 cggtcgggca cagcttctgg ctcagcttgg ccgccggggc cttcggcgtc tgcgccgggg
     8581 tgtccaccgg catcggctcg tcgggcacga tctgctgcac ggccgggttg gcccgcagcc
     8641 ggttcacctc ggccgcggac aggtgcgcgg cgaccgcgtt gacgctgacc agctgggtga
     8701 catcggtgcc accattggct tttatgtccg aaacgaccga ctgctggtcg gtgtgggtgg
     8761 tcgcggtgcg ctgcgagctc tgcgcccgta acttgaggtc gccgtgctgg ttggccagca
     8821 ccacgatgac tcgtccgccg tccgcggcgc cgtcgaccgc gggggccagc ggcaccggcg
     8881 ccgcggccgc gacaccgttg cccagcaaag ccagggccgc gctcatggac agggttgtcg
     8941 ccgctgtgag caggcgatat ctattcacgg gagacacctc gggcagtcgt cgccgaatga
     9001 tcgtcaacgg ccagtcaaac tcgcccgccc gaggcaaaac aagcgacgat cggagctgtt
     9061 ttcgccgctc ggacacgact agcgtgccgc ggacggcagc ccgaaggtga tggtctccct
     9121 tgcggtttcc cgctcctcca cccgcactgg gccgaagcgg cgaagccatt gcaccacttc
     9181 gtccaccagc tcgggcgggg ccgacgcgcc ggcggtgagg ccgaccaccc gcaccccggc
     9241 cagccaggat tccgatatgc ccgaaatatc atccaccagg tatgccggcg tgcccatccg
     9301 ccgcgcgacc tcgaccagtc gcacggagtt ggacgaattg gccgacccca ccaccagcac
     9361 caggtcggcc tcgtcggcca cggcggccag cgaccgctgc cgattggttg tggcgtaaca
     9421 gatgtcgtcg ctgccggggc cgcgcagggc cgggaacctg gcccgcagcg cgtccaccac
     9481 cgcggtcgtc tcgtcgacgg cgagcgtggt ctgggtcagg tacgacaccc gggacgggtc
     9541 ctcgacctca agcgtggcaa cgtcttcggc ggtctcaacc agcaccatcc ggtcgggggc
     9601 ctcgccgagg gtgccctcca cctcctcgtg cccggcatgg ccgatgaaca ccacggtgtc
     9661 gccgcgggcg gcgaagcgcc gggcctcgga gtggaccttg gtcacgagcg ggcaggtggc
     9721 gtcgacgacg tccaggccgc ggtcgacggc ctcggagcgg accgccggcg agacgccgtg
     9781 cgcggagaag accaccgtgg ccccggccgg aacctcggtg agctcgtcga caaaaaccgc
     9841 gccgcgaccg ctgaggtcgg ccaccacatg ggtgttgtgc acggtctgct tgcgcacgta
     9901 gatcgggccg ccgcggcgcg ccagcagttg ctcgacgatc tcgattgccc ggtccacgcc
     9961 cgcgcagaac gaccgcggcg aggccagcag cacagtccgt tcagtggtca cgacgggtca
    10021 ccatcctggc cagcgtgtcc agctcggcgg cggcgcgggc caccggggcc ccctgcgcca
    10081 gttccgccaa cgccagatcg agttggtcga ccgcttcccg ctgggcccac gaccgcccac
    10141 cagccagctc gaccaactcg gcggcgcggg ccagctccac ctcggacagc tcgtcctgcc
    10201 gtccgtacaa cgcggccagt tcgtcggcgg ccggcaggcc cgaggtcagc gcggccacca
    10261 ccggcaggga cttcttgcgg ctgaccagat ccgagtgcgc ggacttgccg gtcacccgcg
    10321 gatctcccca gatgccaagg agatcgtcga ccagttggaa ggccagcccc aggtgctcgc
    10381 cgaacacgcg catgtgctcg acctgctcgg cggtgccgcc gccgtacagc gccccgatgg
    10441 cagtggagca ggccagcagc gcgccggtct tctccccggc catggacagg cattccgaca
    10501 ggtccacatc ggaccgttcc tcgaaggaca cgtcctcgca ctgcccctcg accaggtcct
    10561 gcacggcgga gctgatcatg cgcatggcgt cctgggcgcg ggcgtgcccg ctgccggcca
    10621 gcacgtcgaa ggccagcgtg agcagcgcgt cgccggccag gatggccgag ctgatgccga
    10681 acacggtcca cgcggtcggc cggtgccgcc ggctgacgtc ccggtccatc acgtcgtcgt
    10741 gcagcagcga gaagttgtgc accatctcca ccgcgacggc cgccggcacc gcgtccacaa
    10801 tggaccctcc gacggcctcg gcgcacaggg cggccagcgc cggccggatg gccttgccgg
    10861 cgtcgccgtc gcggggcgtg ccgtcggcgt cccaccatcc gtagtggtag ccggcgacgc
    10921 ggcgcatgga cgtgggcagc gtgtccaccg ccgcccgcat cgccggatcc accacgccac
    10981 ggctccaggc cagcacctca cgggccgacc tgggctgcga gatcacatcg atgggaatca
    11041 ctccctcggt cacgaggcga acatccgcac cgcggacgtg ccgaatccgg tgggcagcgc
    11101 gaagccgcgg ccgcccctgg accggaccag ctcggcggat ccgtatcggg cggtcgtgcg
    11161 gtgccagtcg aggatcgcgg ccatccagtc ctccagctcg cggacgtagc cgtccaccgc
    11221 ccggcgctgc tcggcggtga agccgaactc ctcgcacagc gtgggaatct cgtggtcgcg
    11281 ggtgcggacg aactgctcga tccgcgcggt ggccaggtcg ttgacgatcg cgacggcctg
    11341 atccttgccg cagccgagga agttctccac gaccaggacc atgttcatca gctcgccgtc
    11401 gaactcgatc tccttctggt acgagaagac gtcgttgaca aagcacgcct ggtccatcgc
    11461 cgagcactcg aggccgcgca gctggctggt ggcgaagaac tccgccggga tgagctcggc
    11521 gcggccgaac ccggccaggc tcatcgtcgg cagcgagccc caggtctcgc gccgcatctc
    11581 gatgtagtcc accggatccg ggatccggtt ctgctggtgg tgatcggcct cccagagcca
    11641 ggactcgaac aggcgctcca gggaccgccg gaactgggcg cggtgctggt cggccagcgg
    11701 cagggcggtg cgcagccaca ggtcggccag gccgcgctcg taggcgttgg ccggcgacgg
    11761 catggtcgca cagtccaacg gcgcgaactc caggctgcgc gccacgaacg cgcgcgggcc
    11821 gacgacgtcc ctggtgtgga agaacagcat cgggaacagg tcgtcggcgt aggtgcccca
    11881 gatcgtccac tcagtggcca ggtccagctc gtcctgaccg gcgtccgggt ggaggccggc
    11941 gcagcagcgc gcgaagtcga aaccggccag ttgccggtcg gtccacacgc cctcggtggt
    12001 catgcccatc gtccgggccc actcggtcgt gtgccggcgg gcgttgtcca gcaacgggtt
    12061 cacccgcagg gtgaacggca tggtgaactc gggcaacgag gtcgggccga ccgcgtgcgg
    12121 ggtgtgggtg aaccggttga agcgcttggg aatcccgaac cgcgcgccga gggtacccag
    12181 cccggtcggg ccgccgggca cccagccggc cttatcggcg ttggaattca tgtagcggct
    12241 ggagcgcatg tgccactcgt ggccgccgga ctgccagtcc tgcaagccgc gggcgtagac
    12301 cagcacggcc atccgctcgt ccggccgcag gtggtactcg tcgaacagga tcggcagctc
    12361 ggtaaacacg gtgtgctcga actgctgcat ccgcgaggag atcaggtcgt tggtggcctc
    12421 ggccgcctcc tgggcggtgc agcccagcgc ggtctccagc accaggacca tgttggcatt
    12481 ctcgccttcc tcctccacct cacgctggta ggagaagacg tcgttgcgca ggtgcacgcc
    12541 gtcggcgaag gtgtcgcgca gcacccgcag cggccgggtg cgggccaccg agtccggcac
    12601 ctcggcgccg accgcgacct cgaccaggtt ggccgaccac ggcgcgccgc cgaccttgcg
    12661 gcgcatctcg atgtagtcga tcgggttggc cacccggccc tcgtcgatgt tgatgatctc
    12721 ccacatgcac tcgacgagca ggttgagcgt gctctcgatg aagcgaacct tccactcctg
    12781 ggacatcatc gggatggtgc gttcccacag gtccgtcagc ccggcctcga ccgggttggt
    12841 cggcgtggcg gtgatcgcgc cgtgcagcgg catgaactcg cgcaggccgt ccaggtactt
    12901 cttggcgccc ttgatgtcct tgggcttctt gtacagctcc aggaagtggt cgtcgaagaa
    12961 gaagacccag acgtaccagt cggtgatcag gttgaggatc tcgccggagc actcgggatg
    13021 ggtgtacgcg cacagcagcg cgtagtccat cgcctccagc ttggccggcg accagatgat
    13081 ctcgccgccc tcgaaggccg gggtgtcgat catgtcgaag tcgcgcgccc actggcgggt
    13141 gtggacgcgc gccccctcca ggttcgggtt cagccgcgca gggtgaacca ggtagaactc
    13201 aggcagttcg aacggctgtg ccatcgtggg tggacctcag ttccccagct cgacgtcttc
    13261 cagcacgccc agcgcgtcgg gcaccagcac cgcgcacgag tagtaggtgg agaccaggta
    13321 ggacatgatc gccttctcgt tgatgccggt gaagcgcacc gacaggcccg gctcacgctc
    13381 gtccgggatg ccggtctggt gcaggccgat cacgccgttg tcgtcctcgc cggtgcgcat
    13441 ggccaggatg gacgtggtgt tggtgtcggg gtcgatcggg atcttgtcgc acggcaggat
    13501 cggcaccccg cgccaggaca gcatcgcctt gccgtccacc acgaccggcg ccgggtagat
    13561 gcggcgcgcg gtgagctcgc ggccgaacgc ggcgatggcc ttggggtggg ccaggaagaa
    13621 cttcgtcttg cgccggcggg acaccagctc gtccatgtcg tccggggtgg gcgggccgct
    13681 gcgcggcagc acccgctgct tgaggtcgac gttgtgcagc aacccgaact ccgggttgtt
    13741 gagcatgtcg aactcctggc gctcccgcag cgccgcgatg gtcagccgca actgctcctg
    13801 cacctggtcg tgcggcccgt tgtagaggtc ggcgacacgg gtgtggatgc gcagcatggt
    13861 ctggccgacg gccagctcgt actggcgggg cgacaggtcg tagtccacga acgtgccggg
    13921 caccgtgtac tcgccggagc cgccggaggc cagctcgatc gcggcctcac cgtgcttgtt
    13981 ctgcgccagc gccgtgccgg cgcgcagccg ctccacgtgc gcccgcaacg actccgagcc
    14041 ggccagcagc gggccgagct ggtcgcggga catcgtcagc acgatgcacc gggtggcggc
    14101 ccgcaccgtg tactcccacg gcccgggcga ctcctccatc atctgctggc cgaagtactc
    14161 gccctcggcg aggttgccca gccgggtctc gtcgccgtac ttgccggtgc cgaccatctc
    14221 ggcgcggccg taggcgatca ggaagccggc ctcgctcggg tcgcccgcgg ccacgatggt
    14281 ctcgccggcg gagaactcgc gctgcaccaa gcgatccgcg atggcgtgca gcacggcggt
    14341 gtcctcgaag ccccggtaga gcgggagctc ggtcagcgtc tcggggatga tccggaccgc
    14401 ggaaccggtg ttggtgaagg cgacccggcc ggagccgacc gggaaggtga gccggcggtt
    14461 gacccggtag acggcgccct tggcctcggc ccagggcagc atgtgcagca gccagcgggg
    14521 cgtgatcgcc tgcatctgcg gcacggactt ggtcgtcgtg gccagctgcc gcgcggccgc
    14581 tgtgccaaga ctcaactggg tggaggccgg gtccagggtc tcggtcacga cgaggtgctc
    14641 caatcacgaa cggttgacac agggtggttt gtgcgtctcc aagaccggca aaccagcgcg
    14701 cccgacgtcg ccaacggcag caaaccggtc gggtttgccg ccgttggcga ctgtccggcg
    14761 ggggtttgtg gtgcttggag acacccaaac ccgggtgggc aggtcagttg gcgccgagct
    14821 ggacgtcctc gagaatgccc agcgcgtccg gcaccatcac ggcgcacgag tagtaggcgc
    14881 tgaccaggta cgagatgatc gccttctcgc tgatgttcat gaagcgcacc gacaggcccg
    14941 gctggtactc gtcgggcagc ccggtctggt gcaggccgac cacaccctgg gtgtgctcgt
    15001 cgccggcgcg catcaggatg atcgagctgg tgcgctgctc ggtgatcggg atcttgttgc
    15061 agggcaggat cggcacgccg cgccaggccg gcacctggtg gccgttgaag tcgacgttgc
    15121 ccgggtagat gccggccctg gtgcattcct ggccgaacgc ggcgatcgcc cgcgggtgcg
    15181 ccaggaagac cgtcggcgcc ttccacacgg tggccagcag ctcgtccatg tcgtccggtg
    15241 tcggcgcgcc gccgcgggtg tggatgcgct ggctgaagtc ggcgttgtgc agcaggccga
    15301 agtcacggct gttgaccagc tcgtgctcct ggcgctcgcg cagggcctcg atggtcaggc
    15361 gcaactgctg ctcggtctgg ttcatcggct ggttgtagag gtccgcgacg cggctgtgca
    15421 cccgcagcac ggtctgcgcg acgctgagct cgtactcgcg cggcgcggcg tcgtagtcga
    15481 cgaacgtgcc gggcaggtcg ggctcaccgg tgtggccgga ggcgacgttg atggccgcct
    15541 cgccgctgtc gtcacggccg agcgcggcgt tggcctggaa cagcacgatc tgctcgcgca
    15601 gggccgcgga ctggtcgcac agcgcctgga agtcggcgcg gctgagcgac agcacggtgg
    15661 cgctggtgac cgccctggcg gtgaagtccc agttggcgtc cgggtccacc agcgcgtcgg
    15721 cgccgaagaa ctcgccgtcg gccagcgtgc ccagggccga ctcgtcgccg tacttgccgg
    15781 cgccgatctt gttgatcttg ccgtgggcga tcaggtagac ccggtcggcc gcgctgccgg
    15841 cctcggcgat cacgtcgccg gccgagtact cgtgctggct gaaccggccg gccatggcct
    15901 ccagcacgtc catctcgtcg aagccgcgca gcagcgggag ctcgcccagc tcggccggga
    15961 tcacccggac gtcggcgccg acgttggtga actcgatgcg gccgtcgccg acggtgtagc
    16021 tcaggcgccg gttgacccgg tacacaccgc cgttgacctg tatccagggc agcacgcgca
    16081 tcagccagcg cgaggtgatg ccctgcatct gcgggacgga cttggtcgtg gtggacaggt
    16141 tccgcgcggc ggcggtgccc agactcagct gggactgccc ttgctcaact ccggctcccg
    16201 gctccaacgt ctccgtcacg gcggaacaac tcctcaccag atcgacacag aggaatagaa
    16261 gaaagaatta ggaggaccat tcggccacga cactcgcctt tactctccag acaatggcga
    16321 attaatcgca ggccgatatg gacgccgaca tgagcgaaac tagcaccgcc gttcagcaga
    16381 cgtacagtcg cccgagcggg tgactattgc acggccggaa gtttgacctt ttgttcaccc
    16441 gacccggcta gcagcgatcc accgtcggta gcatcgccca ccgattccac ccggtcaccg
    16501 agcggcaata ggacggcagg gtatcgccgc accgccattc gggttctctt taccggcgaa
    16561 ccctcggggg ccataaccag acgctgacga cagcgaccgg cgcgagctag gtcatgggat
    16621 gtctgtcaaa tcacaccatt gagacaaaaa ccgccaggcc gcggccaata ttaggccgtt
    16681 cgagcgggtg atcgtcacgc ggcgcacacc gacggtcgtt gctgcgtcac aaagcaaagg
    16741 gtgaccgacc acttacccaa cgtcaccaga tcgtgtgcca taagtggccg agagtcgtgc
    16801 gtccccccgg gaatccatcg atccattcgc caccaatacg ccactcgggt cagcaccatc
    16861 cgactaaacc gcaggtcaca cgttcgagtg gcgccgccgc atttcgacgg acccgatgac
    16921 aaaacaagac atcggactgg acacggttga cacttcgtca gaacaacggg ccgcgcggat
    16981 agctcttcgc gatcacctac gagcaccggg taacgtctgg gccccagcgt cggacgggag
    17041 cgagtggatg cgggacggcg gcggcaccgg ccggcggctg atgccgcgcc cggaacgggc
    17101 cgcgagcatc gtggcggccg cggcgcgagc cttcgcccgc ggcggctacg cgggcacctc
    17161 gatggacgac gtggccgccg aggccggcgt caccaagatc attctgtacc ggcaccacaa
    17221 gaccaagaag gacatctaca ccgccgcgct ggacaccacc tggcagcggc tggtggacag
    17281 ctcccagctc ggctacgaca ccgaggccgg actgcgcggc ctgctggcgg cggcccggcg
    17341 cgacgcggcc ggcttcaccc tgctgttccg gcacgcggtc cgagaaccgg agttcgccga
    17401 gtacgcccag cagctggtgg cccagacagt gcaggtggcc gaggagaccc tggccgactc
    17461 ggtgcgggac ccgcggctgc gggcctggct ggctcggggc gtgaccgatc tggtcctcaa
    17521 ctcggtgttg gagtggatca ccactggtga cccggaccgc gacgacgagg ccgccggcct
    17581 gctgttccag accgcggcgg cggtcattgt ccaccaccgg tcaagggcgg tcccgcaccc
    17641 ctcaacacga cgatcggatg gacttcgcga aactgtatac tgagcagttg ctcaaggagt
    17701 actgtcgggc ctccacggtc aaatctgggg aggtgacaat ggcgactggc caattcccgg
    17761 cggatgacgc cgagaccgcc gcgaacgtct tcgctggaga actcaagcgt tggcggacgc
    17821 tgcgcgggct gtcgaggacc acactcgcac gacggatggg ctatgaccgc tcatacgtgt
    17881 ccaaagtgga gagtggggcc aagccgccgt cccgggactt cgcctttcac gcagagaagg
    17941 cgttgcactc gggtggtgcg ctgtacaacg cgtatcggga gcacagcagc tcggtcgagc
    18001 ggtccaaggc cgacggccag ctggtgcgcg ccgcgtcgag gccgacgcag ccgtacgcgg
    18061 acctgatcgt cggcggggtt ccgccggccg ggaggtagat cgggtcacac tgccgatcgg
    18121 gaaccagagg cgcgaacccc cgccgtgccg actaggactc ccgcaaggcg ccagggcggg
    18181 tcgcagccag cgacccgccc tggttctttt cttggccgaa gttgcaggtt taggaaatgt
    18241 tcatccggtg aaggaaccgg gcgaagcgat tcgactcggg aacgcggccc agatctccgg
    18301 cgtgtagaag tgcccgccgg gcagttcctc cacccgcacc gggccggcgg ccagcttggt
    18361 ccaccgctgc gcgttggccg ccggggactt gccgtcctcg gcgccgaaga tgacctgcat
    18421 cggcgcgctg accacggtgc ccggccggta ccggtagctg tggctcacca tcaggtcggc
    18481 ccgcagcagc gacacggcca tctgcaccag ccccggctcg ctgagcagct cctgcggcag
    18541 ctgcccgacg gtgctcatcc agtgcagcag ctcggcatcg gtctggctga tgtgcggtgg
    18601 ctcgccgtcg tcgcgcggcc agtcggtcgg ggcctcgctc gccgacacgg tcagcaccgc
    18661 cggcccacga ccccgccgct ccgcgcgggc cgcgacctcg aacgccatca ccgcgcccat
    18721 gctgtgcccg aacagctggt acggccgggt ggcgacctcc gtgacgacgg cgtcgaccac
    18781 ctcctcgcat agctgctccc actgcgtggc gtacggctcg gtgaaccggc cctcccgccc
    18841 ggggtagcag accaacacca gctccacgtc gtccggcagc tgctgcaccc agcggcggaa
    18901 cggcgcggtg ccgccgccgc tgtagccgat gcacatcagc acccggctgg cctggggccg
    18961 cggccgcggc cggaccaaga tcttggctcc cgtgctcacg gagaccaaag taccggggcc
    19021 cgtagccttg atcggtgcgc ctgctgccgc ctcaggcccg ccgatccgcc gtcggcctgg
    19081 tcgtcctgtc cgttgtcgtg gtcgctgtgg gggcggcgct ctaccacggc caacaacgag
    19141 ccggccggct ggacgacgcc gtcgacgact ggctgttcac ggtcttcggg cagcaccggg
    19201 tgttcctcta ccaactgctg cacgtggccg acctgccggt ggtgatcgcg gtgctggtcg
    19261 tggtgctggt ggcggcgctg atgcgtggcc ggccggacat cgcggcgctg gcggcgatcg
    19321 ggccgctggc ctcgatcggc ctcaccgagg ccgtgctgaa gccgctggtg caccgccgct
    19381 acaacttctt cctgtcctat cccagcggtc acaccgtcgg cacggcctcg gagtgcgcgg
    19441 tgctcggtgt gatcctcctc ggcgcgaccg ggctgaccct tgcgctgcgc gtggcaatgg
    19501 gcgtgctcct gctggtcgtg tgcgcgacgg tgatgctggc gctgatcgtg gacgacttcc
    19561 actacttcac cgacacggtc gccggcgctt ccctgtcggt cggggtggtg gccctgaccg
    19621 cgctggccgt ggacgcggtc acgcggcggc gggtgctcgc ggcggctccg gtctgacccc
    19681 gccgaacggt ggattcccgg gacttgccgg aagttgcact taggtagcta tttacaccgt
    19741 cgcctaccat cgcgaaaatc cttgaccaag gcggactagc gaggtgacgg cgtgcgaagg
    19801 ctcgcgacga cggtggcggc gctgctgatc gtggtcatgg cactaccagc ggcggctgcc
    19861 actactgatt ctgttagcgg gacttctgtc agcgggaccc gggaactgcg cggcatgtgg
    19921 atcgccagcg tggccaacat cgactggccg gccaagccgg gcctgccggt ggcgcagcag
    19981 gaacaggagt acgagagcct gctggaccgg gccaaggcga ccggcgtgaa cgcggttttc
    20041 gtgcagatcc ggccgaccgc ggactcgttc tacccgtcct cgctggagcc gtggtcgcag
    20101 tacctgaccg gcacccaggg ccaggatccc ggctacgacc cgctgaagtt cctggtgtcc
    20161 caggcccacc agcgtgacct ggagttccac gcctggttca acccgtaccg gatcagcctg
    20221 cagagcgacg tgaccaagct ggcgccgaac cacccggccc gactgcaccc ggactgggtc
    20281 gtcagctacg gcgggcagct ctactacaac ccgggcattc cggcggtgcg gcggttcgtg
    20341 gagaaggtca ttctcgacac gactcggcgc tacgacatcg acggcgtgca cttcgacgac
    20401 tacttctacc cgtatcccgt tgccggacaa cagttccccg accagcagac gtttcagcaa
    20461 tacagcggcg gcttcaccaa cgtcacggac tggcggcggg acaacgtcaa caagctgatc
    20521 agcgagctgt cgacgcggat ccactcgatg aagccgtgga tcgccttcgg ggtcagcccg
    20581 ttcggcatct ggcgggacgc ccgcaccgat cccaccggct ccgacacgca gggcggcgtg
    20641 cacgactacg acgacctcta cgccgacacc aggacctgga tccgcaaccg ctgggtcgac
    20701 tacatcgcgc cgcaactgta ctggccggtc ggatacacca tcgccgacta cgggaagctg
    20761 ctgccgtggt gggcccacga ggtcgccggc accggagtgt cgctgtacat cgggcaggcg
    20821 gtgtacaaga tcgggacgcc gagcccggcc gcgtggctgg atcccgagga gatgccccgg
    20881 cacatcgccc tcgaccgcgg cacgcccgag gtcaacggcg acatcctcta caacacgacc
    20941 actttgctgg ccaatccgct tggcttcgcc gaccggctgc gcaccgatct gtacgccaag
    21001 ccggcgatcg tcccggtccg gccgaccgtc gccgggcacg ccccgccgtc gccgatcctg
    21061 ctgccactgt tcgggaacac cctgcactgg ctcggattcg gcacgtccta cgccgtctac
    21121 caggacggcc ggctgctcac caccgtgcgt ggcaccagct tcgccctgcc cgccggccgg
    21181 caccgctacg cggtcaccgc gctggaccgc acccaccacg agagccgccc cagcggcacc
    21241 gaggagtacc gatgagccct gtgcacaaca ggttgaccag gctcgccatg gtgggcaccg
    21301 tcgccggcgc cctcatcgcg cagctcaccg ccgccccggc cgtcgccgcc accgcggccg
    21361 ccccagtcga cttccaccag tggaacagcg actcccagtt ccacagtgga cactccgacg
    21421 ggctgctcgt cggcaacggc ctgacgatcg gccggccggc cggcaccgtg cagcacaccg
    21481 agccggatct gggcaccacc aaggcgtacg actacggcac ctggacctcg ccccgctaca
    21541 gccagcggtt cggggccacg cagctggtcg cgtcgtggaa cgccaccacc ccggccggca
    21601 ccttcctgca ggtggagatg cggggcacgg cgtcgaccgg gacgcagacc gggtggtacg
    21661 tgatgggccg gtgggcctcc agcgacgagg acatccaccg caccagcgtg cccgaccaga
    21721 ccgacgccac cggcaccatc gacgtcgaca ccttcgaggc cgcccagggc gtgcagctga
    21781 tgtcgtacca gctgcgggtc acgctgtacc gcctgcacgg caccagggtc tcgccgcacc
    21841 tgcgcatggt cggcgcgatg acctccgcca tccccgaccg gttctccgtg cccaccagcc
    21901 ccagcggcgg cgcctggggc atcgagctgc cggtgccgcg ctactcccag gacatccacg
    21961 aaggcgagta cccccagtac gacggcggcg gcgaagcctg gtgcagcccc acctccaccg
    22021 agatggtcgt cgagtactgg ggcaaacacc cgacggcgca acaactttcc tgggtcgacc
    22081 ccagctacgc cgaccccagc gtcgactacg ccgcccgcaa cacctacgac tacgactacc
    22141 agggcgccgg caactggccg ttcaacgccg cctacgccgc cagctacggc ctggacgcgc
    22201 acatcacccg gctgcattcg ttgcaggagc tggagaagta catcaagcgg ggcatcccgg
    22261 tgatcacctc gcagtcgttc caggccagcg agctggacgg ggccggctac tccacctccg
    22321 ggcacatcat ggtggtcgtg ggcttcacca agaccggcga cgtgatcgtc aacgacccgg
    22381 cctcccacga cgacgcggcc gtgcgcaacg tctacaagcg cagccagttc gagaacgtgt
    22441 ggcagcgcac cgagcggccc ttgcccggcg gcggcaccgg caccggctca ggcggcgtgg
    22501 tctacatcgt cacgccgcac gggatgcccc tgccctagcg atcagcctgg tgttgtgggg
    22561 attcatcgcg ttggcggcga tcgtcgcggt ggcgacctcg gtgacgaagt catcggcgtc
    22621 gtcaccgagg cggtcggcct gggcggcgag gccggcggcc cgcatgatgc ggccgagggc
    22681 gacgggctcg gtgccgaact gggcgtcgag ttcgacgggc ggcagctcga tggtcaggcc
    22741 ggcggcgacc aggcgggcga cgacctcctc ggcggggtgt tggcgcatgg cgaaaggagt
    22801 gtcggccagg cggtcacgcc agcgtgggcg ggccatgacc tcctcgacga cgtcctgacc
    22861 gtcgcggatc ttcttgcccc ggctccactg caacaccagc gcgccaccgg gtgccacggc
    22921 gcgggccatt tccgcgaggg cgtggtcgat gtcgtcgagc cagtgcagca cccatgagca
    22981 gtgcacgatg tcgaacgtgc cgtccagctt gagctcgcgg gcgtcctgga tgtcgactgt
    23041 gaccgggagt ccctggcaga gatcgcgagt cgcctcgacc atcgaggggg agacgtcgct
    23101 ggcgatgacc gtgaagccgc gttcggccat cgcacgggtg gtttcgccgg tgccacaacc
    23161 gatatcggcc aggcggccgc cgtgcaggtc ggccagttcc agcgcctcga tagcggtgcg
    23221 cagc
//
