LOCUS       NZ_CP073318            20996 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Kutzneria sp. CA-103260 chromosome, complete genome.
ACCESSION   NZ_CP073318
VERSION     NZ_CP073318.1
KEYWORDS    RefSeq.
SOURCE      Kutzneria sp. CA-103260
  ORGANISM  Kutzneria sp. CA-103260
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kutzneria.
REFERENCE   1  (bases 1 to 11609901)
  AUTHORS   Jorgensen,T.S., Gren,T., Kontou,E.E., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Complete Genome Sequence of the Rare Actinobacterium Kutzneria sp.
            Strain CA-103260
  JOURNAL   Microbiol Resour Announc 10 (30), e0049921 (2021)
   PUBMED   34323613
REFERENCE   2  (bases 1 to 11609901)
  AUTHORS   Joergensen,T.S., Gren,T., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2021) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-APR-2021
            Assembly Method :: Flye v. 2.8-b1674; unicycler_polish v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 87.0x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:18:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,326
            Genes (coding)                    :: 10,257
            CDSs (with protein)               :: 10,257
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 9 of 69
            Pseudo Genes (incomplete)         :: 63 of 69
            Pseudo Genes (internal stop)      :: 2 of 69
            Pseudo Genes (multiple problems)  :: 5 of 69
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:59:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6114915
            Orig. end                         :: 6135911
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP073318.1.
            Bacteria and source DNA available from Professor Tilmann Weber,
            Technical University of Denmark, Kemitorvet Building 220, room 327D
            2800 Kgs. Lyngby, Denmark.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20996
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="37"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..20996
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20996
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10996](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10996)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     gene            364..1539
                     /locus_tag="JJ691_RS26755"
                     /old_locus_tag="JJ691_53450"
     CDS             364..1539
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229584.1"
                     /locus_tag="JJ691_RS26755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53450"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_211762394.1"
                     /transl_table=11
                     /translation="MTKILVSGASIAGPTAAYWLHRHGFEVTVVEQAPALRAGGSAVDF
                     RGEQLEILRKMGVLADVEARSTRMGDVTIVDGDGRYQARVPSAVMSGEVEIPRGDLSRV
                     LYEHTKNKVEYVFGDRITALTEHAGGVDVTFAKGAPRTFDLVVGADGAHSGVRSLVFGP
                     ERDFATHLGYYAAYFTVPNHLRLDHAGQLYAEPGLGAMVTSAVDRDTLGAMLVFASEPL
                     SYDRRDTEQHKRILAEKFRTAGWQLPILLDGLAKTDTLFFDSLSQVRLDKWSKGRVVLV
                     GDAAWSAGPGGGGTGLAMVGAYVLAGELATNSGHDQAFAAYERIIRPSAKMGQNQAKRA
                     GGFFAPDSARGIRGRSRVYRVLNLKPLNGLLTWLVNRTADSIELPDYTRAA"
     gene            1536..3353
                     /gene="recQ"
                     /locus_tag="JJ691_RS26760"
                     /old_locus_tag="JJ691_53460"
     CDS             1536..3353
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recQ"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010235635.1"
                     /locus_tag="JJ691_RS26760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53460"
                     /product="DNA helicase RecQ"
                     /protein_id="WP_211762395.1"
                     /transl_table=11
                     /translation="MTDPAHVLRTVFGYDSFRGDQQAIVEHVVAGGDALVLMPTGGGKS
                     LCYQIPALVRDGVGVVVSPLIALMQDQVDALSALGVRAGFLNSTQDPGERQMVEAMFVA
                     GELDLLYLAPERLRMESTPRLLERGKVSLFAIDEAHCVSQWGHDFRPDYLQLSHLHERW
                     PDVPRIALTATATEATRKEIASRLNLEQARHFVSSFDRPNIQYRIAPKNEPKRQLLDLL
                     RTEHSGDAGIVYCLSRSSVDKTAEWLTEQGIPALPYHAGLDSQTRAANQARFLREDGVV
                     MVATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPSTAWLAYGLQDVIQQ
                     RKMIDTSEGDDAHRRRLGQHLNSMLALCETVQCRRGNLLAYFGETLTEPCGNCDTCLTP
                     PESWDGTVAAQKFLSAVFRLDKERRQRFGAGQVIDILLGRKTAKVIQHDHDGLTVFGIG
                     EELNESEWRGVVRQLLAQGLLAVEGDYGTLSLTEASADVLGRRREVRLRRETAVKAPRA
                     ARSTKAAAAVADLPAEAAPVFEQLRAWRAATAREQGVPAYVIFHDATLRQIATQAPTSL
                     AELGTVSGVGENKLAKYGQAILDTLSPGA"
     gene            complement(3668..4135)
                     /locus_tag="JJ691_RS26765"
     CDS             complement(3668..4135)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JJ691_RS26765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_211762396.1"
                     /transl_table=11
                     /translation="MFNRIGTVIIRGFGEFSVFIVKIRSGITVGETLVRADLRLCADVQ
                     MHVHEGARTRRHDWSLIVSVGSSTCSRQPNRRVRSTAIGTPGRLSRRPRVGLRSVARRV
                     RGGVAVGRRASARSVRRGRPEWVWAQRCSVGCADRHKGNRRPVVPRKESPH"
     misc_feature    complement(4016..4018)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4528..7155
                     /locus_tag="JJ691_RS26770"
                     /old_locus_tag="JJ691_53470"
     CDS             4528..7155
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019974.4"
                     /locus_tag="JJ691_RS26770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53470"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_211762397.1"
                     /transl_table=11
                     /translation="MKNKDKPDKANRSIKSRLVGAVLIPSIALVVLWTVAASYLVFDAI
                     YVKLVVSGVREVSIPAVTALASAQKERQLGTAFLSGSSNDLNTLHNQEQQTDKYLATMK
                     TAADALAQNAPPPVVQGLAKLNASIEQLPKIRAEVDSKTIDKAQVFQFYNTMLDSAWSL
                     FDTQARILPAVTVSLGGVTSAAVFRATDLMSRSATLISSGFAAGTLSPADHLQYSNQVA
                     AYHSELDTTVPFVQSDIQNRFNALLAGDDWKQLVDTENAFIEHGAWTKGLAGLPTSQGA
                     WLDLTNRVSDQLVSLTVDQANEVSSQAIDDSNSQLTTVIVGSVLALLAAVGAIFFAVRV
                     SRTLVDRTLVTRLTKMKEEALRSAQERLPDIVRRLRDGQTVDVRAELPDLKFGGDEIGQ
                     VADAFNAAQYTAVTAAVTEAQARDGVHNVFLSIAHRNQGLVHRQLKILDTMERGEENPQ
                     QLERLFQLDHLATRARRNAENLIILGGELPGRRWRKPVKLVDVLRAAVSETELYHRVQV
                     ERGPDVAIVGSAVADTIHLIAELVDNATSFSPPRSQVLVGSTPVARGVVVEVEDQGLGM
                     SDEDRARANAMMIDAPEFDAMALKSDSRLGLFVIARLASRLEINVEFRVSPYGGTRAIV
                     LLPNQLLARDEEPYAESVTGHLVPVVGQPVSGEYQEEDMSGANELDEFWALSRSRLADS
                     VQTTGARQQVAAPPAQAQRVAPPMVGQSGDGQDGFGRDSHRHNGYGQDSFNRAASEIQG
                     IDSHGIDSRGVGAQHIDLPGADIQGVDPLPPSPPAAEVADEEPSFGATGSRPVLPQRQP
                     QHNLAPQLRGDLYDEPEPELDDDQGKSPEEIRRTMSAFQSGSLLGRRAGESSDFSPQAQ
                     GSQD"
     misc_feature    6871..6873
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7155..7583
                     /locus_tag="JJ691_RS26775"
                     /old_locus_tag="JJ691_53480"
     CDS             7155..7583
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686624.1"
                     /locus_tag="JJ691_RS26775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53480"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_211762398.1"
                     /transl_table=11
                     /translation="MNEKATSETDLNWLLDNLVERVVDAQHAVVLSADGLLIGKSRELS
                     RDDSDQLSAMASAFQSLARGAGRHFSGGQVRQTIVEMEHAYLFVTAAGRGACLAVLATE
                     SADVGLIAYEMNLLVKQVGVYLSSAPRSAAAADTGQRA"
     gene            7587..7955
                     /locus_tag="JJ691_RS26780"
                     /old_locus_tag="JJ691_53490"
     CDS             7587..7955
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800903.1"
                     /locus_tag="JJ691_RS26780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53490"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_211762399.1"
                     /transl_table=11
                     /translation="MTEETQWFDEENGPLVRPYAMTGGRTRPGATWLDVATQVVTVPSA
                     TERLGLGPEHQAILELCHRALSVAELASYVNVPLVVIKVLISDLMDRGDVVVRPPAQAL
                     QAPGRDLLQAVLDGVRAL"
     gene            7936..8547
                     /locus_tag="JJ691_RS26785"
                     /old_locus_tag="JJ691_53500"
     CDS             7936..8547
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006238696.1"
                     /locus_tag="JJ691_RS26785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53500"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_211762400.1"
                     /transl_table=11
                     /translation="MVSVHSDQRQAAALAPESVKILVAGGFGVGKTTMVASVSEIPPLS
                     TEELLTEASSGVDDLAGIEGKTTTTVALDFGRITISPKLVLYLFGTPGQDRFWFMWDEL
                     ARGAIGAIVLIDTRRLDTSFAAIDFFERREIPFVVGINHFDGAKHRYEPEEIRSALAIS
                     PGIPIVPCDARQRDASKLILIRLIEHAMSRLPVEGEKASA"
     gene            complement(8604..9980)
                     /locus_tag="JJ691_RS26790"
                     /old_locus_tag="JJ691_53510"
     CDS             complement(8604..9980)
                     /NRPS_PKS="Domain: Beta_elim_lyase (44-422). E-value:
                     4.7e-69. Score: 224.8. Matches aSDomain:
                     nrpspksdomains_JJ691_RS26790_Beta_elim_lyase.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686627.1"
                     /locus_tag="JJ691_RS26790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53510"
                     /product="tryptophanase"
                     /protein_id="WP_211762401.1"
                     /transl_table=11
                     /translation="MPIIEPYRIKVVEPIPLTTREARERSLSRAGYNAFNLRADEVTID
                     LMSDSGTGAVSVAQESAAALGDESYAGARSFYRFHGVLSELTGFPHIFPAHQGRAAERI
                     LFGALLEPGQITLSNTHFDTTRANVELLRCEARDLPCPEAADLDSLDPFKGNIDLAELE
                     RTLTGPDGGRVGFVIMTITNNGGAGQPVSMANIEAAGALCRRHHVPFLLDAARFAENAW
                     LVTQREPGYEHCSPTEVARKAFRLADGCVASLKKDGISPMGAFLAMNDPELASRCELIL
                     TATEGFRTYGGLAGHELDRLAQGLREVLEPDYLRSRAAAAAHLAQLANEAGVDVVQPPG
                     IHALYVNAGRLLPHIPPGRFPGHALACQLYLEGGIRCVELGSLYLGTLDDDYELVTPAP
                     YELVRLALPRRVYTQSHYEYVAETLATIAKNPERVPGYRMVETTPILRHFNSRMAPVQM
                     "
     aSDomain        complement(8715..9848)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JJ691_RS26790_Beta_elim_lyase.1"
                     /evalue="4.70E-69"
                     /label="JJ691_RS26790_Beta_elim_lyase.1"
                     /locus_tag="JJ691_RS26790"
                     /protein_end="422"
                     /protein_start="44"
                     /score="224.8"
                     /tool="antismash"
                     /translation="DLMSDSGTGAVSVAQESAAALGDESYAGARSFYRFHGVLSELTGF
                     PHIFPAHQGRAAERILFGALLEPGQITLSNTHFDTTRANVELLRCEARDLPCPEAADLD
                     SLDPFKGNIDLAELERTLTGPDGGRVGFVIMTITNNGGAGQPVSMANIEAAGALCRRHH
                     VPFLLDAARFAENAWLVTQREPGYEHCSPTEVARKAFRLADGCVASLKKDGISPMGAFL
                     AMNDPELASRCELILTATEGFRTYGGLAGHELDRLAQGLREVLEPDYLRSRAAAAAHLA
                     QLANEAGVDVVQPPGIHALYVNAGRLLPHIPPGRFPGHALACQLYLEGGIRCVELGSLY
                     LGTLDDDYELVTPAPYELVRLALPRRVYTQSHYEYVAE"
     misc_feature    complement(9942..9956)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(10001..10996)
                     /locus_tag="JJ691_RS26795"
                     /old_locus_tag="JJ691_53520"
     CDS             complement(10001..10996)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF023417.4"
                     /locus_tag="JJ691_RS26795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53520"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_249227030.1"
                     /sec_met_domain="indole_PTase (E-value: 2.3e-85, bitscore:
                     286.0, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGERPPAEPPIWASHVSDDLTPVEFSLAIDEDGSPALRMLVEPIA
                     DGSGVLANNRVARRVLAALAERYDIPLDKFEEVWGLFAPGEPSGRFGMWFSVIFRRDAA
                     PDFKVYFNPSARGEERAPALVAEALARLGLDAAYGLVRDRAATRPELDRLTFFALDLHS
                     RSEARVKIYVSHYDAGLATVERAVDGVPGVALDRVREFYSIIGGDLDRRLTGLPSLSSY
                     SFVTGNPDVPNNYSLYLPIRDLVPDDEAAAERVMTLMDQWGLDRPLLERSIEAVCARRL
                     EDGVGLIAYASLRMGPDRSGITVYLSSEAYATMPPRSGARTAVQLSQANL"
     misc_feature    11005..11019
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.52"
                     /tool="antismash"
     misc_feature    complement(11012..11027)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    11263..11277
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     misc_feature    complement(11311..11327)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.23"
                     /tool="antismash"
     misc_feature    11314..11327
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     misc_feature    complement(11423..11434)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.53"
                     /tool="antismash"
     misc_feature    complement(11458..11473)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.81"
                     /tool="antismash"
     misc_feature    11459..11472
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.94"
                     /tool="antismash"
     gene            complement(11520..12428)
                     /locus_tag="JJ691_RS26800"
                     /old_locus_tag="JJ691_53540"
     CDS             complement(11520..12428)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1279: pseudouridine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013225290.1"
                     /locus_tag="JJ691_RS26800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53540"
                     /product="RluA family pseudouridine synthase"
                     /protein_id="WP_211762403.1"
                     /transl_table=11
                     /translation="MRRRAKPPLPQRLGLDPVRMRMPAEGPWRTLREHLVFRLPRVDPA
                     RIDEMLREQRIVDLAGPLGPDAPFVPDGVIWFHRDLPVETPVPFAIDIVHRDDELLVVD
                     KPHFLATIPRGQHIAETALVRLRRDLDLPDLVPAHRLDRVTAGLVLFVIRPEVRGRYQT
                     MFRDRLVHKEYEAVARHRPELALPTTVRSRIVKEKGVIVAQEVPGPANAETIVELVEHR
                     DGLGRYRLRPLTGRTHQLRLHMSGLGVPILHDDFYPELTEKPLDDFSDPLQLLAKVLEF
                     DDPVTGRPRRFESRRALSAWD"
     gene            complement(12550..14736)
                     /locus_tag="JJ691_RS26805"
                     /old_locus_tag="JJ691_53550"
     CDS             complement(12550..14736)
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054695.1"
                     /locus_tag="JJ691_RS26805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53550"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_249228276.1"
                     /transl_table=11
                     /translation="MRTAALAAVVVTLSATAVSIAVAPAASAAVNPGTYTVTNVGSGKC
                     VDAASAATANATVVQQYSCNGSGAQSWTFTATDSGYFRIGAAGAPSQVWDVTNVSTADQ
                     APIQLWLYGGGANQQWQPVDEGNGNFHLVNRNSGKCLDVPGASVNDSVQLQQYACNGTA
                     AQSFSIGGGGSNPPPPPNTPDFGPNVSVFTPSTPQSTIQNKLNQVFNAQQTAQFGAGRY
                     ALLFTPGTYNVDANIGYYEQVAGLGLTPGQVTINGQVHVEADWDGGNATQNFWRDAEGL
                     TINPPGGTNTWAVSQADPLRRVQVNGNLKLDDGGWSSGGFLADSRVTGQVQSGSQQQWL
                     SRNDQIGSWNGQNWNMVFSGVQGAPGNTFPNPPYTTVNNSPVIAEKPYLYVDGSGNYNV
                     FVPALRTNSSGTSWANGNPAGNSLPISQFYIVKSGDTAATINAQLAAGKNLIVTPGIYH
                     LNQALNVTRPDTVILGLGIATFVPDNGVTAISVGDVNGVKIAGLLIDAGTTSSQSLVQV
                     GPNGSSADHSADPTVLSDVHFRLGGATVGKAQQSLVINSNNVITDDTWIWRADHDDNNG
                     TAGWNVNTGANGLVVNGNNVTAYGLFVEHYQQYQTIWNGNGGKTIFYQSEMPYDVPNQA
                     AYMNGSRNGFASYKVGANVTSHEAWGLGVYCFFSANTSVNNYHAFEAPQNGNVKFHDIM
                     DISLGNSGSITHVINDTGAQTPTNTTPVDIVSYP"
     misc_feature    14885..14900
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.55"
                     /tool="antismash"
     misc_feature    complement(14921..14934)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.39"
                     /tool="antismash"
     gene            14966..16357
                     /locus_tag="JJ691_RS26810"
                     /old_locus_tag="JJ691_53560"
     CDS             14966..16357
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JJ691_RS26810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JJ691_53560"
                     /product="hypothetical protein"
                     /protein_id="WP_211762404.1"
                     /transl_table=11
                     /translation="MAGRRPISTGAAVAGLVATLGLAALAVRLPTVAPLLAAAAGWLGV
                     ETWLRHRIGTAGFRHSLHDRLLRSRAGYASWQRARLAQLSPSAPVQFTLAQLDADDGPI
                     PALLPMRPHADLRAYAADELAAAHRPLRRRIATGSTVAAELLRANMVYPVLADVPAPKS
                     RWPREIAGSFLAVGVVVAALAWLEVSWRIDPSAYHRTIPLALSLSLAAVAPLLEVVLAT
                     SRGRRLRLAAITLVPLAFMLCWTVRRSWDANWWQPAFGVREWLVVSTITVVSLGLALAT
                     SSPRNRHRLPPRRVAQLSWLSIASVAAAGLGLLVPVLAGPPPTPAFPHVSSCSLLSREA
                     LARLSPNIDRGPASTFTEATVNGCEWFQGRGPAPIEFVAIDAYVGSGDVAASTREFTLA
                     THVVPGTRRDLPGPCDQAAEVVGERGVEVVLRCANLVLSVFSSAHDPGLAERLAAEAAR
                     VATAG"
     gene            16386..19736
                     /locus_tag="JJ691_RS26815"
                     /old_locus_tag="JJ691_53570"
     CDS             16386..19736
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020647255.1"
                     /locus_tag="JJ691_RS26815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53570"
                     /product="TM0106 family RecB-like putative nuclease"
                     /protein_id="WP_211762405.1"
                     /transl_table=11
                     /translation="MFTPTDLADLLECEHRSVLDQALTAGLPGAPRPDPGGDQLAVKHG
                     QAHELAVLERLRAAHDVVEISGDDPVEATLAALRAGTPVIYQAVFRDGDLTGRADFLIA
                     DADGRYEAYDTKLARHARPAAVLQLTAYADALRRTGFPTGPHMHLLLGDGSDVSLRVDD
                     FVPLLDRLRAKLSVREPALPSRLWDDARPACATCKFLSTCESGREADRDLSLVAGMRAD
                     QRRKLVEAGLGTIDALAVAEPEDRPRDLSATTFTALRAQAAIQVRQDATGKISYEVVDG
                     SELATLPAPSPGDVFFDMEGDPFALAGTGLEYLFGAVTTAGFTPFWAHSRAAEKVAFEQ
                     FVDFATARLAEHPGAHVYHYAPYEVTALKRLAAVHGTREEAVDELLRGGQLIDLYAVVR
                     KALRVSQRSYSIKYLEPLYMPAARDGDVKTAVSSIEAYEEYLTLRQLGDPRAAEVLQGI
                     SDYNEYDCVSTRELFLFLHRVRVEAEIELVEESISDDLVTQTEDLVAAERRAERAARLA
                     ALVDPLLADLPDNPLDATDDEKARALLAASVGYHRRETNPAWWEFFRQVAAPLSDLEVD
                     TTCAVPVSVRAEEWQPPAGRTKLAKRVLTLVCDPDRPHPYAFGDQVRLRYGDSTRDALV
                     TAATAEELTLIESAKPDDTDTGRPNAVLPGSPVRPQPKDEAVADLAQLAVDALPSLPSH
                     PGTDLLRRTPPRLRGGRSLPSGDDDLVRTVIETVDLLDGSTLAVQGPPGAGKTYLAGKL
                     IAHLVGSGRTVAVTSTSHKAVENVLRAATSSAPTLPCAKRPKKAPEKDVPWEQPKDNPG
                     LARWRAEHTDGHLVGGTAWTFANAAIRAEPFDVLIIDEAGQFALADALAVSMCARNLVL
                     LGDPQQLPQVVQGTHPAGAEASALGHLIGDNDVIPPSLGYFLDQSRRMHPAVCEPVSRL
                     SYAGLLHAHPSAAERSIDGIDAGLYLASVDHRGNTTRSVEEAAAVVDIVRSLHGRKWTD
                     GDVRPLGDEDILVVAPYNLQARVVTRALEVAGFAGVRVGTVDRFQGQEAPVVITTMTSS
                     SAVDLPRGLDFLLSRNRLNVALSRAQAVAVLVCSPKLVEADIRTVDQMRLVSGMIGLMN
                     AAQRWPHGL"
     gene            19726..20130
                     /locus_tag="JJ691_RS26820"
                     /old_locus_tag="JJ691_53580"
     CDS             19726..20130
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024092.4"
                     /locus_tag="JJ691_RS26820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_53580"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_211762406.1"
                     /transl_table=11
                     /translation="MDSDSRIRLAIEEHWRASERGDLQAEHAIYAVDAILDYPQSGERF
                     HGRAAISAQRGGHPADRHFTIQRITGRGPLWVSECVITYDGSPSHSVSIMEFADGHVIH
                     ETQYFADPFPAPASRASLADPMPGRSLPEA"
ORIGIN
        1 gcacaccggt accggcggtt ccgtgcgcct gaacagcttt gtcgacggcg aggaagtggt
       61 gctggaggtc cgggacagcg ggagcgggat ctcgcccgag gacctgccgc acgtgttcga
      121 ccggttctgg cgggccgaga agtcccgcag ccggcagacc ggcggcagcg gcctgggcct
      181 ggccatcgtg cgcaagctgg tcgaggccca cggcggcagg gtcggggtgg agagcgaact
      241 cggcgtgggg accgtgttcc gggtccggct gccggcccgc tgacggcctc gtcagcggtt
      301 ggtcagccga cggtcagggc cggccgcgac ggtgtggaca cacaccgatc gatggaggca
      361 gtcatgacga agatcctggt ttccggggcg agcatcgccg gcccgaccgc cgcctactgg
      421 ctgcaccgcc acggcttcga ggtcaccgtc gtcgagcagg ccccggcgct gcgggccggc
      481 ggctcggccg tcgacttccg gggcgagcaa ctggagatcc tgcgcaagat gggcgtgctg
      541 gccgacgtcg aggcccgcag cacgcggatg ggcgacgtga cgatcgtcga cggcgacggc
      601 cggtaccagg cgcgggtgcc gtcggcggtg atgagcggcg aggtggagat cccccgcggc
      661 gacctcagcc gggtgctgta cgagcacacc aagaacaagg tggagtacgt cttcggcgac
      721 cggatcaccg cgctgaccga gcacgccggc ggcgtggacg tcaccttcgc caagggcgcg
      781 ccccgcacct tcgacctggt ggtcggcgcg gacggcgcgc actccggggt gcggtcgctg
      841 gtcttcgggc cggagcggga cttcgccacc cacctcggct actacgccgc ctacttcacc
      901 gtgcccaacc acctccggct ggaccacgcc ggccagctgt acgccgagcc gggcctcggc
      961 gcgatggtga cgagcgctgt cgaccgcgac accctgggcg cgatgctggt cttcgcgtcc
     1021 gagccgctgt cctacgaccg gcgtgacacc gagcagcaca agcggatcct ggccgagaag
     1081 ttccggaccg ccggctggca gctgccgatc ctgctggacg gcctggcgaa gaccgacacg
     1141 ctgttcttcg actcgctcag ccaggtgcga cttgacaagt ggtcgaaggg ccgtgtggtg
     1201 ctcgtcggcg acgccgcgtg gtcggccggc ccgggcggcg gcggcaccgg cctggccatg
     1261 gtcggcgcct acgtgctggc cggcgagctg gccacgaatt cgggccacga ccaggctttc
     1321 gccgcctacg agcggatcat ccgaccctcc gccaagatgg gccagaacca ggccaagcgg
     1381 gccggcggct tcttcgcgcc ggacagcgcg cggggcatcc gcggccgcag ccgcgtgtac
     1441 cgggtgctca acctcaagcc gctcaacggt ctgctgacgt ggctggtcaa ccgcaccgcc
     1501 gactcgatcg agttgccgga ctacactcgg gcggcgtgac agatccggct catgtgctgc
     1561 gcaccgtctt cggctacgac tcgttccgcg gcgaccaaca ggccatcgtg gagcatgtcg
     1621 tggccggcgg cgacgcgctg gtgctgatgc cgaccggcgg cggaaagtcg ttgtgctacc
     1681 agatccccgc gctggtccgg gacggcgtgg gcgtggtggt ctcgccgctg atcgcgctga
     1741 tgcaggacca ggtggacgcg ctgagcgcgc tcggcgtgcg ggccggtttc ctgaactcca
     1801 ctcaggatcc gggcgagcgc cagatggtgg aggccatgtt cgtggccggc gagctggacc
     1861 tgctgtacct ggcgccggag cggctgcgca tggagtccac gccgcggctg ctggagcggg
     1921 gcaaggtgtc gctgttcgcc atcgacgagg cgcactgcgt ctcccagtgg gggcacgact
     1981 tccggccgga ctacctccag ctgtcccacc tgcacgagcg ctggccggac gtcccgcgga
     2041 tcgcgctgac ggcgaccgcg accgaggcca cccgcaagga gatcgccagc cggctcaacc
     2101 tggagcaggc ccggcacttc gtgtccagct tcgaccggcc caacatccag taccgcatcg
     2161 cgcccaagaa cgagcccaag cggcagctgc tggacctgtt gcgcaccgag cactccggcg
     2221 acgccggcat cgtctactgc ctgtcccggt cctcggttga caagacggcg gaatggctta
     2281 ccgagcaagg gattccggcg ctgccctacc acgccgggct ggacagccag acccgcgccg
     2341 ccaaccaggc ccggttcctg cgcgaggacg gcgtggtcat ggtggccacc atcgccttcg
     2401 gcatgggcat cgacaagccg gacgtacgct tcgtggccca cctggacctg cccaagtcgg
     2461 tcgagggcta ctaccaggag accggccgcg ccggccggga cgggctgccg tccaccgcgt
     2521 ggctggccta cggcctgcag gacgtgatcc agcagcgcaa gatgatcgac acctccgagg
     2581 gcgacgacgc gcaccggcgg cggctcgggc agcacctgaa ctcgatgctc gcgctgtgcg
     2641 agaccgtgca gtgccggcgc ggcaacctgc tggcctactt cggcgagacg ctcaccgagc
     2701 cctgcggcaa ctgcgacacc tgcctgacgc cgcccgagtc gtgggacgga accgtggcgg
     2761 cgcagaagtt cctgtccgcg gtgttccgac tggacaagga gcgccggcag cgcttcgggg
     2821 ccgggcaggt catcgacatc ctgctgggcc gcaagaccgc caaggtgatc cagcacgacc
     2881 acgacgggct cacggtgttc ggcatcggcg aggagctcaa cgagtcggag tggcgcggcg
     2941 tggtgcggca gctgctggcc cagggcctgc tggccgtgga gggcgactac ggcacgttgt
     3001 cgctgaccga ggccagcgcc gacgtgctcg gccgcaggcg cgaggtccgg ctgcgccggg
     3061 agaccgccgt caaggcgccc cgggcggccc gctccaccaa ggccgccgcc gcggtcgccg
     3121 acctgccggc cgaggccgcc ccggtcttcg agcagctgcg ggcgtggcgt gccgcgaccg
     3181 cccgcgagca gggcgtgccg gcctacgtga tcttccacga cgcgacgctg cgccagatcg
     3241 ccacccaggc cccgaccagc ctggccgagc tgggcacggt cagcggcgtc ggcgagaaca
     3301 aactcgccaa atacggccag gccatcctgg acaccctcag cccgggggcg tgaacaacac
     3361 gcacagtggt cgttaaaagg acataaattc gaccacgcac acgcgacaaa tgtgggacgc
     3421 ggcaccacaa gaccgtcgac acaggatacc cacagcgacc ttgtgccgta ttcccggcgc
     3481 gccgatgaga gcccgtccgc cgccggaatc ggcggccgga atcccaccgt tccaccgaga
     3541 aggcgctgac cagaggcccg tcagcgacac ggactcccgg tccactgtcg cgacgggcgc
     3601 acgggcgtcg aacagcgcag gcagcgggcg cagaccggcc ggcaaaaacg ttttcgcacg
     3661 aatatcgtca atgcggtgac tcttttctcg gcacgaccgg tcggcggttg cccttgtgac
     3721 ggtcggcgca gccgacactg caccgctggg cccagaccca ctccggccga ccgcgccgga
     3781 ccgaccgcgc cgaggcgcga cgaccgaccg ccacgccgcc gcgcactcgc ctggcgacgg
     3841 accgcagtcc cacccgcggc cgccgcgata gtcggcccgg cgtgccgatc gctgtcgatc
     3901 ggacgcggcg gttcggctga cgggagcacg tcgaggagcc gaccgacacg atcagcgacc
     3961 agtcgtgacg cctcgtgcgt gcaccttcgt gcacgtgcat ctgcacgtcg gcacataaac
     4021 gcagatcagc gcggacaagc gtttcaccga cggtaatgcc ggaccgaatt ttcacgatga
     4081 agacagagaa ttcgccgaac ccgcgaatga tcactgtacc gatccggttg aacaccgata
     4141 gcgacgaaac tttcggcccc atatcccgcc gaaccgcagg gtgcgtacca ccgaacgagt
     4201 gaaagatcgg ggccagaacc gcccctaggc gacagtccga cctaacgact tgcgaccgtt
     4261 cggcgcatgc ttcggcgcgc tcaccgcagt agtcgggaaa aggccgcctc gccgagccgc
     4321 ggactgttcg cgtgcgaact ggaacgtgct agatttcctg gccgcaagaa gatcaagatc
     4381 ggtgagcgga tgcttcctgt ccgaagacgg ccacgagtgc ggccggcaag gaacggggag
     4441 tgaccgccgc cgaaatcgcc gaccgtccgc caggacggtc ggtgtgaggc cacgaaccgc
     4501 acacctcagg gtcggtgatg gagcgtcgtg aagaacaagg acaagccgga caaggcgaac
     4561 cggtcgatca agtcgcgatt ggttggcgcg gtgctgattc ccagtatcgc gctggtcgtg
     4621 ctgtggacgg tggccgcatc gtacctggtc ttcgacgcga tctacgtgaa actggtggtc
     4681 agcggcgtcc gtgaggtgtc gatcccggcg gtcaccgcgc tggcctcggc gcagaaggaa
     4741 cgccagctgg gcaccgcctt cctgagcgga tcgtcgaacg acctgaacac gctgcacaac
     4801 caggagcagc agaccgacaa gtacctggcc acgatgaaaa ccgcggccga cgcgctggcc
     4861 cagaacgcgc cgccgccggt cgtgcagggg ctggccaagc tcaacgccag catcgagcag
     4921 ctgcccaaga tccgcgccga ggtcgacagc aagaccatcg acaaggccca ggtcttccag
     4981 ttctacaaca cgatgctgga ctcggcctgg agcctgttcg acacccaggc ccgcatcctg
     5041 cccgccgtca ccgtctcact gggcggcgtc acctcggcgg cggtcttccg cgccaccgac
     5101 ctcatgtccc gctcggccac gctgatctcc agcggcttcg ccgccggcac gctcagcccg
     5161 gccgaccacc tccagtactc gaaccaggtc gcggcctacc actccgagct ggacaccacc
     5221 gtcccgttcg tgcagtccga catccagaac cggttcaacg cgctgctggc cggcgacgac
     5281 tggaagcagc tcgtcgacac cgagaacgcg ttcatcgagc acggcgcctg gaccaagggc
     5341 ctggccggcc tgcccaccag ccagggcgcc tggctggacc tgaccaaccg ggtctccgac
     5401 cagctggtct cgctcaccgt cgaccaggcc aacgaggtct ccagccaggc catcgacgac
     5461 agcaacagcc agctcaccac cgtgatcgtc ggcagcgtgc tggccctgct ggccgcggtc
     5521 ggcgccatct tcttcgcggt ccgggtgtcc cgcaccctgg tcgaccgcac cctggtcacc
     5581 cgactgacca agatgaagga ggaggcgctg cgctcggccc aggagcggct gcccgacatc
     5641 gtgcggcggc tgcgtgacgg ccagaccgtg gacgtgcgcg ccgagctgcc cgacctgaaa
     5701 ttcggcggcg acgagatcgg gcaggtggcc gacgcgttca acgccgccca gtacaccgcc
     5761 gtcaccgcgg ccgtcaccga ggcccaggcc cgcgacggcg tgcacaacgt gttcctcagc
     5821 atcgcccacc gcaaccaggg cctggtgcac cggcagctga agatcctgga cacgatggaa
     5881 cgcggcgagg agaacccgca gcagctggag cgcctgttcc agctggacca cctggccacc
     5941 cgggcccggc gcaacgcgga gaacctgatc atcctgggcg gcgagctgcc cggccggcgc
     6001 tggcgcaagc cggtcaagct ggtcgacgtg ctgcgggccg cggtgtcgga aaccgagctg
     6061 taccaccggg ttcaggtgga gcgcggcccg gacgtggcca tcgtcggctc cgcggtggcc
     6121 gacaccatcc acctgatcgc cgagctggtg gacaacgcga cgtcgttctc gccgccgcgc
     6181 tcccaggtgc tggtcggcag cacgccggtg gcccgcggcg tggtggtcga ggtcgaggac
     6241 cagggtctgg gcatgagcga cgaggaccgg gcccgggcca acgcgatgat gatcgacgcc
     6301 cccgagttcg acgccatggc cctgaagtcc gactcccggc tgggcctgtt cgtgatcgcg
     6361 cggctggcgt cccggctgga gatcaacgtc gagttccggg tctcgcccta cggcggcacg
     6421 cgggccatcg tgctgctgcc caaccagctg ctggcccgcg acgaggagcc ctacgccgag
     6481 tccgtcaccg gccacctggt gccggtcgtc ggccagccgg tgtccggcga gtaccaggag
     6541 gaggacatga gcggggccaa cgagctggac gagttctggg cgttgagccg gtcccggttg
     6601 gccgactcgg tgcagaccac cggcgcgcgc cagcaggtcg ccgcgccgcc ggcgcaggcc
     6661 cagcgggtcg cgccgccgat ggtcggccag agcggcgacg gccaggacgg cttcggccgc
     6721 gacagccacc ggcacaacgg ctacggccag gacagcttca accgggccgc cagcgagatc
     6781 cagggcatcg actcccacgg catcgactcc cgcggcgtgg gcgcgcagca catcgacctc
     6841 cccggcgctg acatccaggg cgtcgacccc ttacccccgt cgccgccggc cgcggaggtc
     6901 gcggacgagg agccctcgtt cggcgccacc ggcagccgtc cggtcctgcc gcagcggcag
     6961 ccccagcaca acctcgcgcc gcagctgcgc ggcgacctct acgacgagcc ggaacccgag
     7021 ctcgacgacg accagggcaa gtctcccgag gagatccgtc ggaccatgtc ggcattccag
     7081 agcggttccc tgctgggccg ccgcgccggc gaatcctcgg acttttcacc gcaggcacag
     7141 ggaagtcagg actgatgaac gagaaggcca cttcggagac cgacctcaac tggctgctgg
     7201 acaacctggt cgagcgggtc gtcgacgccc agcacgccgt cgtgttgtcg gcggacggac
     7261 tgctgatcgg caagtccagg gaactctcgc gcgacgactc cgaccagttg tcggcgatgg
     7321 cctcggcctt ccagagcctg gccagaggcg ccggccggca cttcagcggc gggcaggtgc
     7381 ggcagaccat cgtcgagatg gagcacgcct acctgttcgt gaccgcggcc ggccggggcg
     7441 cgtgcctggc ggtgctggcc accgagagcg ccgacgtcgg cctgatcgcc tacgagatga
     7501 acctgctcgt caagcaggtc ggcgtgtacc tgagctcggc gccgcgcagc gcggcggccg
     7561 cggacaccgg tcagagggcg tagccgatga ccgaggagac acagtggttc gacgaggaga
     7621 acggcccgct cgtccggccg tacgcgatga ccggcgggcg cacccggccc ggcgccacct
     7681 ggctggacgt agccacccag gtggtgaccg tgccgtcggc caccgagcga ctcggcctcg
     7741 gtcccgagca ccaggccatc ctcgagctgt gccaccgcgc gctgtcggtg gccgagctcg
     7801 cctcgtacgt gaacgtgccg ctcgtcgtga tcaaggtcct gatcagtgac ctgatggatc
     7861 gcggcgacgt ggttgtccgt cccccagcac aggccctgca agcgccgggt cgcgacctcc
     7921 tccaggcggt gctcgatggt gtccgtgcac tctgaccagc gtcaggccgc ggcgctggcc
     7981 cccgagtcgg tgaagatcct ggtggccggc ggcttcggcg tcggcaagac caccatggtc
     8041 gcgtcggtca gcgagatccc gccgctgagc accgaggaac tactgaccga ggccagcagc
     8101 ggcgtcgacg acctcgccgg catcgaaggc aagacgacca ccacggtggc gttggacttc
     8161 ggccgcatca cgatcagccc caagctggtg ctgtacctgt tcggcacgcc cgggcaggac
     8221 cggttctggt tcatgtggga cgaactcgcg cgcggcgcca tcggcgccat cgtgctgatc
     8281 gacacccgtc ggctggacac cagcttcgcg gcgatcgact tcttcgaacg gcgcgagatc
     8341 ccgttcgtgg tgggcatcaa ccacttcgac ggggccaagc accgctacga gccggaggag
     8401 atccgctcgg cgctggcgat cagcccgggt atcccgatcg tgccctgcga cgcccgtcag
     8461 cgggacgcca gcaagctgat cctgatccgg ctgatcgagc acgcgatgag ccggctgccg
     8521 gtggagggcg agaaggcttc cgcctgagac aacggaaaaa gggccccgcc gacgcgtccg
     8581 gcggggccct ttcctgtgtg ggcctacatc tgcacgggcg ccatgcggga gttgaagtgc
     8641 cgcaggatcg gcgtggtctc aaccattcgg tagccgggca cgcgctccgg gttcttggcg
     8701 atggtggcca gcgtctccgc gacgtactcg tagtggctct gggtgtagac ccgacgcggc
     8761 agcgccagcc ggaccagctc gtacggtgcg ggcgtgacga gttcgtagtc gtcgtcgagg
     8821 gtgcccaggt acagcgaacc cagttcgacg cagcggatgc cgccctccag gtacagctgg
     8881 caggccaggg cgtggccggg gaagcggccc ggcgggatgt gcggcagcag gcgcccggcg
     8941 ttgacgtaca gggcgtggat gcccggcggc tgcacgacgt cgacgccggc ctcgttggcc
     9001 aactgggcca ggtgggccgc ggccgccgcc cgggaccgca ggtagtcggg ctcaagcacc
     9061 tcgcgcaggc cctgggccag ccggtcgagc tcgtggccgg ccaggccgcc gtaggtgcgg
     9121 aagccctcgg tggcggtgag gatcagctcg cagcgcgagg ccagctccgg gtcgttcatg
     9181 gccaggaacg cgcccatcgg cgagatcccg tccttcttca ggctggccac gcagccgtcg
     9241 gccagccgga acgccttgcg ggccacctcg gtcggcgagc agtgctcata tccgggctcc
     9301 cgctgggtca ccagccacgc gttctcggcg aaccgggccg cgtccaacag gaacggcacg
     9361 tggtggcgac ggcagagcgc gccggcggcc tcgatgttgg ccatcgacac cggctggccg
     9421 gcgccgccgt tgttggtgat cgtcatgatc acgaagccga cccggccgcc gtccggcccg
     9481 gtcagcgtcc gctccaactc ggccaggtcg atgttgccct tgaacggatc cagactgtcc
     9541 aggtcggccg cctccgggca cggcaggtcg cgcgcctcgc agcgcaacag ctcgacattg
     9601 gcccgggtgg tgtcgaagtg agtgttgctc agggtgatct ggcccggctc caatagcgcg
     9661 ccgaacagga tgcgctccgc ggcccggccc tgatgtgccg ggaagatgtg cgggaacccg
     9721 gtcagctcgc tgagcacccc gtggaatcgg tagaaggagc gggcgcccgc gtaggactcg
     9781 tcgcccagcg ccgccgccga ctcctgcgcc accgacaccg cgccggtgcc cgagtccgac
     9841 atcaggtcga tggtgacctc gtcggcccgg aggttgaagg cgttgtagcc ggcacgagac
     9901 agtgagcgct cacgggcctc ccgcgtggtc agcgggatcg gctcgacgac cttgatccgg
     9961 tacggttcga tgatgggcat gggatgaccc ttccacctct ctacaggttc gcttgtgaaa
    10021 gttggacggc tgtgcgcgcc ccggaccgcg gcggcatcgt cgcgtacgcc tccgacgaca
    10081 ggtacaccgt gatcccggac cggtccggac ccatccgcaa cgaggcgtag gcgatcagcc
    10141 cgaccccgtc ctccagtcgc cgtgcgcaca cggcttcgat ggagcgctcc aacagcggtc
    10201 gatccaggcc ccattgatcc atcaatgtca tcacccgctc cgccgccgcc tcgtcatcgg
    10261 gcacaagatc gcggatcggc aggtacaagg agtagttgtt cggcacgtcc ggattccccg
    10321 tgacgaacga atagctcgac agcgagggca gcccggtcag ccgtcgatcg aggtcgccgc
    10381 cgatgatcga gtagaactcg cggacccggt ccaacgcgac gcccgggacg ccgtccacgg
    10441 cgcgctcgac ggtggccagg ccggcgtcgt agtgggagac gtagatcttc acccgggcct
    10501 cggaccggga atgcagatca agggcgaaga aggtcagccg gtccagctcc ggccgggtgg
    10561 ccgcacggtc cctgaccagt ccgtacgccg cgtcgagccc caaccgggcc agcgcctccg
    10621 ccaccagcgc cggggcgcgt tcctcgccac gggccgaggg attgaagtag accttgaaat
    10681 ccggtgcggc gtcccgacgg aaaatgacgg agaaccacat cccgaaacgt ccactcggct
    10741 cgcccggcgc gaacagtccc cacacctcct cgaacttgtc gagtggaatg tcgtaccgtt
    10801 cggccagcgc ggcgagcacc cgccgcgcga cccgattgtt ggccaacaca ccggagccgt
    10861 cggcgatcgg ttcgacgagc attcgcaggg ccggcgaacc gtcctcgtca atcgcgagcg
    10921 agaattcgac cggcgtcagg tcgtccgata cgtgcgaggc ccatatcggc ggctcggccg
    10981 ggggccgctc acccaccgca cccaatagca atgtgagaat gctcaccggc gtctcggcgt
    11041 ccgccaagcc caccgcgaca cacagactgc gcagctgagc gcacacatgt tcacgcaacg
    11101 aaagggaccg cacgatcatc cttcgactcc gatgactcgt tacattaatc acctgtccag
    11161 cgtccctgca agctgtccag aaacctacac aggccccccg aaccggcata ccgcctatcc
    11221 ggcgtttgca tgctcaactt tccataaccc agcggagttg gcgacgcatt gtgagaatgt
    11281 caacggaagt cgaacatgtc gacctcgggc acgttttcgc atatcaacag gggtgcgccg
    11341 accggagtcc ggaattcacc cactcgcgag acgttaagca tgctaggatc tcgcgtccgc
    11401 gctgcgagca aacgcacaca ccgttaacgt ttgccactga gcgcgacccc atcgtattcg
    11461 aacaaagatt cgaacgcaac gaatgtccac tttgggacaa gcactttagg acagcggcgt
    11521 cagtcccagg cggacagtgc tcggcggctc tcgaagcggc ggggcctccc ggtcaccgga
    11581 tcgtcgaact ccagcacctt ggccagcagc tggagtggat cggagaagtc gtcgaggggc
    11641 ttctcggtga gctccggata aaagtcgtcg tgcaggatgg gcacgccgag accgctcatg
    11701 tgcagccgca actggtgggt gcggccggtg agtgggcgca gccgatagcg gccgaggccg
    11761 tcgcggtgct cgacgagctc cacaatggtc tcggcgttgg ccggcccggg cacctcctgc
    11821 gccacgatca cacccttctc cttgacgatt cggctgcgca ccgtggtcgg cagcgccaat
    11881 tcgggacggt gccgggcgac ggcctcatat tccttgtgca ccaagcgatc ccggaacatc
    11941 gtctggtaac ggccgcgaac ctcggggcgg atgacgaaca gcaccaggcc ggccgtgacc
    12001 cggtccaacc ggtgcgcggg gacgagatcc ggcaggtcga gatcccggcg caggcgcacc
    12061 agggcggtct cggcgatgtg ctgtccccgc gggatggtgg ccaggaagtg cggcttgtcc
    12121 acgaccagca gctcgtcgtc gcggtgcacg atgtcgatgg cgaacggcac cggggtctcc
    12181 accggcaggt cccggtggaa ccagatcacc ccgtccggca cgaacggcgc gtccgggccc
    12241 agcggccccg ccaggtcgac gatccgctgc tcccgcaaca tctcgtcgat gcgcgccggg
    12301 tccactctgg gcagtcggaa caccaggtgc tcgcgcagcg tccgccacgg cccctccgcc
    12361 ggcatccgca tccgcaccgg gtcgaggccg aggcgctgcg gcagcggcgg cttggctcgg
    12421 cgtctcatcg ggactcagcg tacggcaagc gcgcgaaggg ccctttcccc gtgaggaaag
    12481 ggcccttcgg atcagggtgg aggagggcgg tcgaggaggc cccacggcgc ccctcgacca
    12541 cccccgggat cacgggtagc tgacgatgtc gaccggggtg gtgttggtcg gggtctgcgc
    12601 accggtgtcg ttgatgacgt gggtgatcga cccgctgttg cccagcgaga tgtccatgat
    12661 gtcgtggaac ttgacgttgc cgttctgcgg cgcctcgaac gcgtggtagt tgttcacgct
    12721 ggtgttggcg ctgaagaagc agtacacgcc caggccccac gcctcgtggc tggtgacgtt
    12781 ggcccccacc ttgtacgagg cgaagccgtt gcgggagccg ttcatgtacg ccgcctggtt
    12841 gggcacgtcg tagggcatct cgctctggta gaagatcgtc ttgccgccgt tgccgttcca
    12901 gatggtctgg tactgctggt agtgctcgac gaacaggccg taggcggtga cgttgttgcc
    12961 gttgacgacc aggccgttgg cgccggtgtt gacgttccag ccggcggtgc cgttgttgtc
    13021 gtcgtggtcg gcgcgccaga tccaggtgtc gtcggtgatc acgttgttgc tgttgatgac
    13081 cagcgactgc tgggccttgc cgacggtcgc gccgccgagc cggaagtgca cgtcggacag
    13141 cacggtcggg tcggcgctgt ggtcggccga cgagccgttc gggccgacct gcaccagcga
    13201 ctgcgagctg gtggtgccgg cgtcgatcag caggccggcg atcttcacgc cgttgacgtc
    13261 gccgaccgag atggcggtga cgccgttgtc cggcacgaag gtcgcgatgc ccaggcccag
    13321 gatcacggtg tcgggccggg tgacgttgag cgcctggttg aggtggtaga tgccgggcgt
    13381 gacgatcagg ttcttgccgg cggccagctg cgcgttgatg gtcgcggcgg tgtcgccgga
    13441 cttgacgatg tagaactggc tgatcggcag cgagttgccg gccgggttgc cgttggccca
    13501 cgaggtgccc gagctgttgg tgcgcagcgc cggcacgaac acgttgtagt tgccggagcc
    13561 gtccacgtac aggtagggct tctcggcgat caccgggctg ttgttgaccg tcgtgtacgg
    13621 cgggttcggg aacgtgttgc cgggcgcgcc ctgcacgccg gagaacacca tgttccagtt
    13681 ctggccgttc cagctgccga tctggtcgtt gcgggacagc cactgctgct gcgagccgga
    13741 ctgcacctgg ccggtgaccc gggagtcggc caggaagccg cccgaggacc agccgccgtc
    13801 gtccagcttc aggttgccgt tgacctgcac ccggcgcagc gggtcggcct gggacacggc
    13861 ccaggtgttg gtgccgccgg gcgggttgat ggtcaggccc tcggcgtcac gccagaagtt
    13921 ctgggtggcg ttgccgccgt cccagtcggc ctcgacgtgc acctggccgt tgatggtgac
    13981 ctggcccggg gtcagaccga ggccggcgac ctgctcgtag tagccgatgt tggcgtccac
    14041 gttgtaggtg ccgggcgtga acagcagggc gtagcggccg gcgccgaact gcgcggtctg
    14101 ctgggcgttg aagacctggt tgagcttgtt ctggatggtc gactgcggcg tggacggcgt
    14161 gaagaccgag acgttcgggc cgaagtccgg ggtgttgggc ggcgggggcg ggttgctgcc
    14221 gccgccaccg atggagaacg actgcgcggc cgtgccgttg caggcgtact gctgcagctg
    14281 gacgctgtcg ttcacggacg cgccgggcac gtccaggcac ttgccgctgt tgcggttgac
    14341 caggtggaag ttgccgttgc cctcgtcgac cggctgccac tgctggttgg cgccgccacc
    14401 gtagagccac agctggatcg gcgcctggtc ggccgtggag acgttggtga cgtcccagac
    14461 ctgcgacggc gcgccggccg cgccgattct gaagtagccg gagtcggtcg cggtgaaggt
    14521 ccacgactgg gcgccggatc cgttgcagct gtactgctgc acgacggtgg cgttggcggt
    14581 ggcggcggag gccgcgtcca cgcacttccc gctgccgacg ttggtgacgg tgtaggtgcc
    14641 gggattcacc gcggcgctgg ccgccggcgc cacggcgatg ctgactgcgg tcgcggacag
    14701 ggtcacgacc accgccgcga gcgcggcggt tcgcacaggg gtcacagtcc cacctcgctg
    14761 acgctcggcg agtctgcgac cgaggccgct gtgttgaatg gtgccttcgc aagctcagtc
    14821 acgaggccct cctgcttcgc tggaaagagg acaggtgtca gttggcggcc ccgacaaggc
    14881 cgaatgttat gggggtcaca ggaaagcgtc aatacacgac ttaaaataag tcagagacga
    14941 tccgaccggc gaggatcatg ctcgcatggc tggaaggcgt ccgatcagca ccggggccgc
    15001 cgtggccggg ctggtggcga cgctgggcct ggccgccttg gcggtgcggc tgccgacggt
    15061 cgcgccgctt ctggcggccg ccgccggctg gctgggcgtc gaaacctggc tgcgccaccg
    15121 aatcggcacc gccgggttcc ggcacagtct gcacgaccga ctcctacggt cccgcgcggg
    15181 gtacgcgtcg tggcagcggg cgcgtttggc tcagctgagc ccatccgcgc cggtccagtt
    15241 cacgctcgcc caactggacg ccgacgatgg gccgatcccc gccttgctgc cgatgcggcc
    15301 ccatgccgac ctccgcgcct acgccgccga tgagctggcg gccgcccacc ggccgctgcg
    15361 acgacgcatc gcgacgggtt cgaccgtggc ggcggagctg ttgcgcgcca acatggtcta
    15421 cccggtgctg gccgacgtgc ccgcgccgaa gtcccggtgg cccagggaaa tcgctggatc
    15481 tttcctggct gttggtgtgg tagtggcggc gctggcgtgg ctggaggtgt cctggcgcat
    15541 cgatccgtcg gcctaccacc gcacgatccc gttggcgctg agcctgtccc ttgccgccgt
    15601 ggcgccgctg ctggaggtcg tgctggccac ctcgcgcggc cgtcggctcc ggctcgcggc
    15661 gatcaccctg gtgccgttgg ccttcatgct gtgctggacg gtccgccggt cctgggacgc
    15721 gaactggtgg cagccggcgt tcggcgtccg cgaatggctg gtcgtgtcaa cgattaccgt
    15781 cgtgtcgctg ggtttggcgc tggccacttc ctcgcctcgc aaccgccacc ggctgccgcc
    15841 gcggcgggtc gcccagctgt cgtggctgtc gatcgcctcg gtcgcggccg ccgggctggg
    15901 gctgctggtg ccggtgctcg ccgggccgcc gccgacgccg gccttcccgc acgtgtcgtc
    15961 gtgctcgctg ctgtcccgcg aggcgctggc ccggctctcc cccaacatcg accgcggccc
    16021 ggcttcgacc ttcaccgagg ccaccgtcaa cggctgcgag tggttccagg gccgtggccc
    16081 ggcgccgatc gagttcgtcg ccatcgacgc ctacgtcggc agcggtgacg tcgcggcctc
    16141 gacgagggag ttcaccctgg ccacgcacgt cgtgcccggg acgcggcggg acctgcccgg
    16201 gccgtgcgac caggccgccg aggtggtcgg cgagcgcggc gtcgaggtgg tgctgcgctg
    16261 cgccaacctg gtgctgtcgg tgttcagctc ggcccacgac ccggggctgg ccgaacgact
    16321 cgccgcggag gcggcgcgcg tggcgaccgc gggttgatct cccgctgtgc gagactggcc
    16381 cggcgatgtt caccccaacg gacctggccg acctgcttga gtgcgagcac cggagcgtgc
    16441 tcgaccaggc gctgaccgcc ggactgcccg gcgcgccgcg ccccgacccc ggcggcgacc
    16501 aactggccgt caaacacggg caggcccacg aactggcggt gctggagcgc ctgcgcgcgg
    16561 cacatgacgt ggtcgagatc tccggcgacg acccggtgga agccaccctc gcggcgctgc
    16621 gcgccggcac gccggtgatc taccaggcgg tgttccgcga cggcgatctc accggccgtg
    16681 cggacttcct catcgccgac gcggacggcc ggtacgaggc ctacgacacc aagctggccc
    16741 ggcatgcccg gccggcggcg gtgctccagc tcaccgcgta cgcggatgcc ttgcgccgca
    16801 ccggttttcc caccggcccg cacatgcacc tactgctcgg cgacggcagt gacgtgtcgc
    16861 tgcgggtgga cgacttcgtg ccactgctgg atcgcttgcg ggccaagctg tccgtgcgcg
    16921 agccggcgct gccgtcgcgg ctgtgggacg acgcccggcc ggcctgcgcc acgtgcaagt
    16981 tcttgagcac ctgcgaatcc gggcgggagg ccgaccggga tctgtcactg gtcgccggca
    17041 tgcgggccga ccagcggcgc aagctggtcg aggccggtct gggcaccatc gacgcgctgg
    17101 ccgtcgccga gcccgaggac cgtccgcgcg acctgtccgc caccacgttc accgcgctgc
    17161 gggcgcaggc ggcgatccag gtgcggcagg acgccaccgg gaagatcagc tacgaggtgg
    17221 tggacggctc cgagctggcc acgctgccgg cgcccagccc cggcgacgtg ttcttcgaca
    17281 tggagggcga cccgttcgcg ctggccggca ccgggctgga gtacctgttc ggcgcggtga
    17341 ccacggccgg gttcacgccg ttctgggccc attcccgggc ggccgagaag gtggcgttcg
    17401 agcagttcgt cgacttcgcc accgcccggc tggccgagca tcccggcgcg catgtgtacc
    17461 actacgcgcc gtacgaggtg acggcgttga agcggctcgc cgccgtgcac ggcacccgtg
    17521 aggaggccgt ggacgagctg ctgcgcggcg gccagctgat cgacctgtat gccgtggtgc
    17581 gcaaggcttt gcgggtgtcg cagcggtcgt actccatcaa gtacctggag ccgctgtaca
    17641 tgccggccgc gcgggacggc gacgtgaaga cggccgtgtc cagcatcgag gcgtacgagg
    17701 aatacctgac gctgcgccaa ctcggcgatc ctcgggcggc cgaggtgttg cagggcatca
    17761 gcgactacaa cgagtacgac tgcgtgtcca cccgggagct tttcctcttc ctgcaccggg
    17821 tccgggtgga agccgagatc gagctggtcg aggagtccat ttcggacgat ctcgtcacgc
    17881 agaccgagga cctcgtcgcc gccgagcgcc gggccgagcg ggccgcccgg ctcgccgcac
    17941 tggtcgaccc cctactggcc gacctgcccg acaatcccct ggacgccacc gacgacgaga
    18001 aggcccgggc tctgctggcc gcgtcggtgg gctatcaccg ccgggagacc aatccggcgt
    18061 ggtgggagtt cttccgccag gtggccgccc cactgtccga tctggaggtg gacaccacct
    18121 gcgccgtgcc ggtttccgtg cgggccgagg aatggcagcc gccggccggg cggaccaagc
    18181 tggccaaacg cgtgctgact ctcgtctgcg acccggatcg gccgcatccc tacgctttcg
    18241 gcgaccaggt tcggctgcgc tacggcgatt ccacccggga cgccctcgtg accgcagcga
    18301 cggccgagga gctgacgctc atcgagagcg ccaagcccga cgacaccgac accggtcgtc
    18361 ccaacgccgt gctgcccggc tcgccggtgc ggccgcaacc caaggacgag gccgtcgccg
    18421 atctcgccca gctcgccgtg gacgctttgc cttccctgcc aagccatccc ggcaccgatc
    18481 tgctgcgccg cactcccccg cggctgcgcg gcggccggtc actgccttcc ggcgacgacg
    18541 atctcgtgcg gaccgtgatc gagaccgtcg acctgctcga cggctcgacc ctggccgtgc
    18601 aggggccgcc cggggccggc aagacctatc tggccggcaa gctcatcgcg cacctcgtcg
    18661 gctccggccg caccgtggcc gtcacctcga ccagtcacaa ggccgtcgag aacgtcctgc
    18721 gggcggccac ttcctccgcg ccgacgctgc cgtgtgccaa gcgccccaag aaggcccccg
    18781 agaaggacgt gccctgggag cagcccaagg acaaccccgg gctggcccgg tggcgggccg
    18841 agcacaccga cgggcacctg gtcggcggca ccgcgtggac cttcgccaac gccgccatcc
    18901 gggccgagcc gttcgacgtg ctcatcatcg acgaagccgg ccagttcgcg ctcgccgacg
    18961 ccctcgccgt ctccatgtgc gcccgcaacc tcgtgctgct cggcgatccc caacagctgc
    19021 cgcaggtcgt tcagggcacc catcccgccg gcgccgaggc ctccgccctg gggcacctca
    19081 tcggcgacaa cgacgtgatt cccccgtcgc tgggctactt tctcgaccag tcccggcgta
    19141 tgcaccccgc cgtctgcgaa cccgtgtcgc ggctgtcgta cgccggtctc ctgcacgccc
    19201 atccctccgc cgccgagcgc tccatcgacg gcatcgacgc cggcctctat ctcgcctccg
    19261 tcgaccaccg cggcaacacc acccgctccg tcgaggaagc cgccgccgtg gtcgacatcg
    19321 tgcggtccct gcacggtcgc aagtggacag acggcgacgt ccgccccttg ggggacgagg
    19381 acatcctcgt tgtcgccccc tacaacctcc aggcccgcgt cgtcaccagg gccctggagg
    19441 tcgccggctt cgcgggcgtc cgtgtcggca ccgtcgaccg cttccagggc caggaggccc
    19501 cggtcgtgat caccaccatg acctcctcct ccgccgtcga cctcccccgg ggcctcgact
    19561 tcctgctctc ccgcaaccgc ctgaacgtcg ctctctcccg cgcccaggcc gtcgccgtcc
    19621 tcgtctgctc ccccaagctc gtcgaggccg acatccgcac cgtcgaccag atgcgcctgg
    19681 tctccggcat gatcggcctc atgaacgccg cgcaacggtg gccccatgga ctctgactcc
    19741 cggatcaggc ttgccatcga ggagcactgg cgcgcctccg aacgcggcga ccttcaggcc
    19801 gaacacgcca tctacgccgt cgacgccatc ctcgactatc cccagtccgg tgaacgcttc
    19861 cacggccgcg ccgccatctc cgcccaacgt ggcggtcacc ccgccgaccg ccacttcacc
    19921 atccagcgca tcaccggccg cggccccctc tgggtgagcg agtgcgtcat cacctacgac
    19981 ggctcgccgt cccactccgt cagcatcatg gagttcgccg acggccacgt gatccacgaa
    20041 acccagtact tcgccgaccc cttccccgcc cccgcctccc gggcctccct agcggatccc
    20101 atgcccggcc gctccctccc cgaggcctga gcccccggcc ggccccctct ccaacgccgg
    20161 cccctggccc tccttcacgc acctgagtgg ctcatttgac tttccgggag ccagcttcgc
    20221 catgtgagtg gctcatttgg ctcctgcgcc caactgagcc actcacatgc cgctcccccg
    20281 ccttcccacg gtcaactgag ccactcacgt ggtctctgcg cctaagtgag ccactcacgt
    20341 acggtcctga gccgccccct cgatgagctg agccacgcac accgcgggca agtacgccgt
    20401 cgaccccagt agcccaagaa gttgtccaca ggcctcatgc cggcaacggg cccatccaca
    20461 ggccgcctca ttccaagatc cactaacccc tcccaccggt agactggagc ggggccggcc
    20521 cccgggttgg gcgggggtgt gttcggccgg ggtgtgttca gtggcctggg ctcagcggcc
    20581 cagaccggcg tctcttgccc ggacgatggc ctgggcgcgg tcggcgacct ggagcttggc
    20641 gaagatcgag gagatgtggt tgccgacggt cttggccgcc aagtgcagct tgtcgcagat
    20701 ctgggggttg gccaggccgg cggcgatgag gtcgaggact tcgcgttcac ggtcggtgag
    20761 ctgggggaag ggaaggttgg gcaagtcgcc gggaccgccg ctgagcaggg cgtcgacgcg
    20821 gcgggcgatg ccggggccga agatgacgcc gccctcggcg acgcagcgga tggcgcgcag
    20881 gatctcctcc tggtcggcgc ctttgaggat gtagccacga gccccggcgc ggatggcggc
    20941 gaagacggac tcgtcgtcct cgaacatggt gagcatgagc acggcggtgg ccgggg
//
