LOCUS       NZ_CP073318            21137 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Kutzneria sp. CA-103260 chromosome, complete genome.
ACCESSION   NZ_CP073318
VERSION     NZ_CP073318.1
KEYWORDS    RefSeq.
SOURCE      Kutzneria sp. CA-103260
  ORGANISM  Kutzneria sp. CA-103260
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kutzneria.
REFERENCE   1  (bases 1 to 11609901)
  AUTHORS   Jorgensen,T.S., Gren,T., Kontou,E.E., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Complete Genome Sequence of the Rare Actinobacterium Kutzneria sp.
            Strain CA-103260
  JOURNAL   Microbiol Resour Announc 10 (30), e0049921 (2021)
   PUBMED   34323613
REFERENCE   2  (bases 1 to 11609901)
  AUTHORS   Joergensen,T.S., Gren,T., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2021) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-APR-2021
            Assembly Method :: Flye v. 2.8-b1674; unicycler_polish v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 87.0x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:18:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,326
            Genes (coding)                    :: 10,257
            CDSs (with protein)               :: 10,257
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 9 of 69
            Pseudo Genes (incomplete)         :: 63 of 69
            Pseudo Genes (internal stop)      :: 2 of 69
            Pseudo Genes (multiple problems)  :: 5 of 69
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:59:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3123813
            Orig. end                         :: 3144950
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP073318.1.
            Bacteria and source DNA available from Professor Tilmann Weber,
            Technical University of Denmark, Kemitorvet Building 220, room 327D
            2800 Kgs. Lyngby, Denmark.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21137
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="amglyccycl"
                     /region_number="22"
                     /rules="(DOIS or ValA or salQ or strH or strK1 or strK2 or
                     NeoL or SpcFG or SpcDK_glyc)"
                     /tool="antismash"
     cand_cluster    1..21137
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /kind="single"
                     /product="amglyccycl"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21137
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11137](-)"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11137)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
     gene            445..1593
                     /locus_tag="JJ691_RS13555"
                     /old_locus_tag="JJ691_27000"
     CDS             445..1593
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.4"
                     /locus_tag="JJ691_RS13555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27000"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_211769127.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.9e-35, bitscore:
                     121.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGHESRTDEKVWELLEHISISDPDNEPFEKAVQLAPLIDDPDEL
                     LAQAARHALVPSLADFLVRADLLRLVPHHAQRHLLGTLHWNRFKTRRHAHEAERITTVL
                     ASEGVRVACTKGVVCQQTLYDGRGIRHFGDIDLMVLPEHREKAAEVLYRLGYAGATKFD
                     HRTGELLEISRSLQLMYQLYPDHLPHFFRIPADDDGMPYFMVDVAYNLTWYGSSWQIPM
                     DRALDNVVGVDSGSVTLPALDVPYGFIFVVLHLFREGWFERTVREKDVRLGQCADVWRF
                     WERFGRDRVDDIRKVLAEYGLEPAIAWVCRHVDDVYRGTITGELGLDEYCDDGWLHSAG
                     ATDGGYLVWQGSLRDRLRDRRPPVLRPGGEPSFAAAARVSPA"
     misc_feature    1641..1651
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            1645..3249
                     /locus_tag="JJ691_RS13560"
                     /old_locus_tag="JJ691_27010"
     CDS             1645..3249
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="JJ691_RS13560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27010"
                     /product="radical SAM protein"
                     /protein_id="WP_211769129.1"
                     /sec_met_domain="PF04055 (E-value: 2.1e-16, bitscore: 60.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRPYLPGTVNSHRVLLVSGLWPYDTVDEKKAVGRLNIFHNRELR
                     EGITALVGADSVYDIGLRGADGGQPLFRPNTVSEPTLVSVALRSLLPDDVHVTDQELAD
                     LLHSDGRSEEDLRAAARDAVCLLSTSYVTNFPDLRKVVDKLRELSVGYVVAGGYLATRN
                     PDAVLDCGVDAVVVGDAEDSIAALLRCLRGGDDWSSVPNLWYGTEDGGKAYTFDRLVAL
                     DSIPVTMPDGDLSGISVPYESMRGCPYKCAFCSYPLVTTKWRFKSAEKLLADWQAIERS
                     GAKEIIALDSTFTIPPKRLRDFLDLYHEAGLTIPWGAYSRVTPLRNEETVIQLKRANNR
                     WLSIGFESGSQHMLDLMNKGTRLKDAYPALAHLRKHRVAPWSNFIIGYPGETEETVDAT
                     TTFMSEHIFGFYGIYVFNIRDRAMPVLSDPGANVHWEDVGSDWTHSTMNSDQATELRWR
                     TYVRVCLANPDAINVDVFRGSNVEKEYGVWDRAFSALKHIEAWALRWIDPTTVAAEGGD
                     DIAGSERALRDLLAPLG"
     misc_feature    2617..2619
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3261..4250
                     /locus_tag="JJ691_RS13565"
                     /old_locus_tag="JJ691_27020"
     CDS             3261..4250
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019121.4"
                     /locus_tag="JJ691_RS13565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27020"
                     /product="hypothetical protein"
                     /protein_id="WP_211769130.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 5.7e-11,
                     bitscore: 41.5, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIIENRPVGVLAGGRGVLQGSSEVVAGRVKTLLESADIAAAVFQ
                     YGSEEFAAALARGDLRLLQDVTYGVYGRAESLAAAAGLGFVGTGARQAEVYDKVRLKTF
                     LSRSRVRTPAHVVLDAHAQPSSWSAISLLAGPIVVKPATADLLSAGVRFFDAADPWQPE
                     LREHIGQLFALDQTVLVERYVPGLEICLGYEVSRRGFEMYRPLTITKEALLFDHSVKTS
                     KRYAFTPVDVPASALRQLSRLGRTMAAEFDLTGCFYVNAIVADDGDVSVFDAGATVGLT
                     EHSYFPAAAALRGDALDDLLVRQFVEPVEDLLRRESATQREPAEMETR"
     gene            4251..5174
                     /locus_tag="JJ691_RS13570"
                     /old_locus_tag="JJ691_27030"
     CDS             4251..5174
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (46-287). E-value: 1e-38.
                     Score: 125.4. Matches aSDomain:
                     nrpspksdomains_JJ691_RS13570_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013247.4"
                     /locus_tag="JJ691_RS13570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27030"
                     /product="aminotransferase class IV"
                     /protein_id="WP_211769131.1"
                     /transl_table=11
                     /translation="MDAWLDGETVAEESVTLHVNSVTAALGTAFFEAMRCYPVSRRGAA
                     VFRFEAHYRRLVRSLSVVGARLPLTAEDLLSAVAEIVSANSAAGQACYIKVMVFWDTVL
                     SGTSLVDLGEFTPRVAVFLRTTPDSFFHNCPRLRCRISSWRRMDDNAMPAQAKATANYY
                     NARLGLTEALAAGYDNAIFLNGRGAVTEAAEANVFVVDRRAMTVATPSLDSGVLPGVIR
                     DSVLEVLRGDARFQVCEERLHPMDLYAADEVFLTNTAQLVRQVSEIDGRQLATGPGTLA
                     GDLRAELVDILFRPDRRPEWFAALPI"
     aSDomain        4389..5111
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JJ691_RS13570_Aminotran_4.1"
                     /evalue="1.00E-38"
                     /label="JJ691_RS13570_Aminotran_4.1"
                     /locus_tag="JJ691_RS13570"
                     /protein_end="287"
                     /protein_start="46"
                     /score="125.4"
                     /tool="antismash"
                     /translation="FRFEAHYRRLVRSLSVVGARLPLTAEDLLSAVAEIVSANSAAGQA
                     CYIKVMVFWDTVLSGTSLVDLGEFTPRVAVFLRTTPDSFFHNCPRLRCRISSWRRMDDN
                     AMPAQAKATANYYNARLGLTEALAAGYDNAIFLNGRGAVTEAAEANVFVVDRRAMTVAT
                     PSLDSGVLPGVIRDSVLEVLRGDARFQVCEERLHPMDLYAADEVFLTNTAQLVRQVSEI
                     DGRQLATGPGTLAGDLRAE"
     gene            5217..5993
                     /locus_tag="JJ691_RS13575"
                     /old_locus_tag="JJ691_27040"
     CDS             5217..5993
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017026.4"
                     /locus_tag="JJ691_RS13575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27040"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_211769132.1"
                     /transl_table=11
                     /translation="MLIDGLTRRFERQKPAVDYMAEHFGVGPVADFGCGNGIPLAYQAD
                     RHPDLFFVGVDHSTDILNRNLARDRANVLLVTADLASRTFPDDSLGSAVFNRSLHEVYS
                     LFGEAGLKQAVTAARNALHPGGRVLVYENAVPSRDRVALRIVTDEVRELFTRFIRDYSV
                     RPVPWTQKTPDTVVLQEDDALEFLTKYRDPDWESEMREVHFLYSLEEWDAVLASCGLEK
                     VAVRRFDDRQILATDGVEPGWEIADFKHVLVYRRPA"
     gene            5990..6802
                     /locus_tag="JJ691_RS13580"
                     /old_locus_tag="JJ691_27050"
     CDS             5990..6802
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1204: transketolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012670.4"
                     /locus_tag="JJ691_RS13580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27050"
                     /product="transketolase"
                     /protein_id="WP_211769134.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.7e-14,
                     bitscore: 52.9, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTATAAAREAWDLIRQRDKARQIREQTLRLSQGRPHHLGGQLSC
                     VEILVSIFYGHAPTLPDTRFVLSKGHACITLYAILADLGLIPAEELETIMEAGGRLLGH
                     PCRTTTPAVDASTGSLGMGLSMAAGMALAARTTGRETHVHALLGDGEMQSGQVWEALML
                     MGHHQLDTVHTVIDCNGAQADGDTADIIGLEPLPARLEAMGLEAVECDGHDLAALNEAL
                     AEPRRGRPRVIVARTVKGKSVPMMEGDNRWHSGALSRDQLANALASLY"
     gene            6813..7721
                     /locus_tag="JJ691_RS13585"
                     /old_locus_tag="JJ691_27060"
     CDS             6813..7721
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014798.4"
                     /locus_tag="JJ691_RS13585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27060"
                     /product="transketolase C-terminal domain-containing
                     protein"
                     /protein_id="WP_211769135.1"
                     /transl_table=11
                     /translation="MKRFSRLLLDTMETDSRVVVLDADLSRSSGSAAVADRWPDRFVNT
                     GIAEQNTMGVAAGMALLGLRPIVHTFAAFATMRACEQIRTSIAYQQLNVTICASKGGLA
                     ASRSGPTHHATEDLAIMRAIPGMTVLAPRDFRDLTASFPEVLDLPGPVYIRMPPEQEPD
                     DLTGSVPSIGAGVVLQKGADVVLAFTGSMTRTVRQSAERLSAKGLDVGIIYLPSVKPLD
                     DGLIEQCARTARLVVTVEEHNVIGGLGSAVAEVLSARRSAPLLRLGVEDRFCYASGTHE
                     EMLDAYCVSVEELVQQVMERC"
     gene            7788..9959
                     /locus_tag="JJ691_RS13590"
                     /old_locus_tag="JJ691_27070"
     CDS             7788..9959
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012554.4"
                     /locus_tag="JJ691_RS13590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27070"
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="WP_211769136.1"
                     /transl_table=11
                     /translation="MYPELATFHQTVVGRLPDTCLELLPRTALVVVPPDGLMQGVHRRL
                     LDEHGEHVVAFRFRVLSQRLAERLYLDGLVTRAPGRHIRSWWIKSKLFDLGEALVLLMR
                     HPTDPGFQATVTALKGASDPMLAKPGTYREHYRTPNKTFGLLHSSDDLLSMLYEANVLF
                     EPEGLTQLLTKPCWDPAHRALVSGYEGGVSVRRIESYRVLYRLKRRLLAEPTAAGVLPV
                     SLLEAVEENYRTALDVVAADPGHIAETVTVARLLVEERGLLDGIHPHAGVLAAPQEEDL
                     RVAGAEEQRVRVKTALACLRTLTEPTALRTAGFESLESSLEALGIPLTALERTVLESLF
                     FFYATDPPRATVTTSAGAARRSAAMPNAYQQVLDAAEKLEDYPLSPSDVAELGRTGLEA
                     TAGRLAFMIVTPDAVHRGLHADTLTKVHNAGFRVLAHQTRNLRDSDIEELYKDGLRAKI
                     LENRRTHWYLTRKGLGFGTSLGLLLHHPDGDACERLLRLKGASKPAEATPDSVRGSLGS
                     YSKILALMHSSDTPPAVLRECLLYFTAEQVRGALSQLAEHPTPQGTPISLLVEALSPTT
                     SYDDPFTVLYALKIRISHALAAHPLTGAELQPMLEQHLSGLRAMRATLSADRVPWPSRT
                     AAVGHELEREHKLLVEGALAQSPQSAPGESLERLAWHRLALTARQLADQQGFGQLDMDQ
                     VRAALHAAHVHLTSWEALLVENLVFFWEP"
     misc_feature    8793..8795
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11137)
                     /locus_tag="JJ691_RS13595"
                     /old_locus_tag="JJ691_27080"
     CDS             complement(10001..11137)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     amglyccycl: salQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005152974.1"
                     /locus_tag="JJ691_RS13595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27080"
                     /product="sedoheptulose 7-phosphate cyclase"
                     /protein_id="WP_249227893.1"
                     /sec_met_domain="salQ (E-value: 1.5e-182, bitscore: 605.8,
                     seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.8e-62, bitscore:
                     210.1, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAQREVSYEVRCQDGLFRPEHTDLLEIGSGRDARCRRFVVVDSN
                     VDLLYGEAIRAYFEHHGVDHAVVVVRADETVKDLATAERIAEELDCFGIARRREPVVVV
                     GGGVLMDVVGLVASLYRRGTPFIRVPTTLVGFVDAGVGVKTGVNFNGHKNRLGTYMAAD
                     LTLLDRTFLSTVDRRNIANGIAEILKIALVKDFRLFELLEVHGRLLLDEKLQGRTPVGD
                     RAAVTVLHAAIQGMLEELHPNLWEAELERRVDYGHTFSPEVEMRALPAMLHGEAVCVDM
                     ALTTVMAYRRGLLTRVERDRVLAVMSALELPVWHPVIKHDLLVHALEDTVRHRDGQQRL
                     PLPVGIGDVTFVNDVTEAEIEAVVAMHRDLCAGPAFVV"
     gene            complement(11182..12000)
                     /locus_tag="JJ691_RS13600"
                     /old_locus_tag="JJ691_27090"
     CDS             complement(11182..12000)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013429.4"
                     /locus_tag="JJ691_RS13600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27090"
                     /product="TIM barrel protein"
                     /protein_id="WP_211769137.1"
                     /transl_table=11
                     /translation="MSCKVGLTEWRLAASGPEAVRLAALVGADGVQLDFGGPGRGEPID
                     GPGRIEALRAAAAECGVDLLALAGNQFNDVGLTAESEIVRPLLIRLLDAAVELGVPLVF
                     VPSFRRSAIDGLESFTRTAEVLRWASAEAAARHVLLANENVLDGERARALAEEIDSPAF
                     RLVLDTFNPVATGRCVAELVALASDLLADQVHLKDGPPTVGASPLLGSGIGKLDETVDA
                     LRRHQAPVHAFVLENDYRDGDSVRLAADLAWARRRAELFPARHSIRGAGR"
     gene            complement(11997..12734)
                     /locus_tag="JJ691_RS13605"
                     /old_locus_tag="JJ691_27100"
     CDS             complement(11997..12734)
                     /NRPS_PKS="Domain: PKS_KR (9-162). E-value: 1e-08. Score:
                     27.2. Matches aSDomain:
                     nrpspksdomains_JJ691_RS13605_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.4"
                     /locus_tag="JJ691_RS13605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27100"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_211769138.1"
                     /transl_table=11
                     /translation="MGSLTGRRMIVVGGSTGIGRGIADAWAGAGAEVVVCSRRRPAVGP
                     GLSWVRLDLSEPDHARERLVGLSTGRVDAACFSAVHYGDKRARFSEVSEVEWHTQLEVN
                     VTGLWLTLRALLPALRRAQSGLFVGVSSEVAFNGGPGRSGYAASKAAAKSLLDSLTQEE
                     SHVRVVQVLPAGMVDSPGIRRRRPPDFDYSGYMAPSAFGRVAVELALSGGEGHHGDSLV
                     VDGNGEWRSARGGLPVSQSRTLP"
     misc_feature    complement(12027..12029)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(12249..12707)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JJ691_RS13605_PKS_KR.1"
                     /evalue="1.00E-08"
                     /label="JJ691_RS13605_PKS_KR.1"
                     /locus_tag="JJ691_RS13605"
                     /protein_end="162"
                     /protein_start="9"
                     /score="27.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="IVVGGSTGIGRGIADAWAGAGAEVVVCSRRRPAVGPGLSWVRLDL
                     SEPDHARERLVGLSTGRVDAACFSAVHYGDKRARFSEVSEVEWHTQLEVNVTGLWLTLR
                     ALLPALRRAQSGLFVGVSSEVAFNGGPGRSGYAASKAAAKSLLDSLTQE"
     CDS_motif       complement(12618..12707)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JJ691_RS13605_0001"
                     /evalue="4.10E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="JJ691_RS13605"
                     /protein_end="39"
                     /protein_start="9"
                     /score="9.8"
                     /tool="antismash"
                     /translation="IVVGGSTGIGRGIADAWAGAGAEVVVCSRR"
     gene            complement(12734..13813)
                     /locus_tag="JJ691_RS13610"
                     /old_locus_tag="JJ691_27110"
     CDS             complement(12734..13813)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019845.4"
                     /locus_tag="JJ691_RS13610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27110"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_211769139.1"
                     /sec_met_domain="ADH_N (E-value: 2.1e-08, bitscore: 33.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGRHRAIVRGMGTTSVELRPTVVPGPGELSIAPLYAGLCGTDIQ
                     MLRGLRDDPAPVIGHEGVARVAAAGAGVSDELAPGTLVTVNPTHPADPSFLLGHNVDGL
                     FQERTLVPAPAVTGGLVIPLPATTDVTLAPLLEPLAVVRYALGELRRFAMATLLVVGDG
                     TIGHIAVRASRCWLGADVRVVLLHNSEAGLVFSGAGPHSADELLTDLAEVALDGPTAAL
                     VATPRDATVPALEVAIAAGAEVIDIVGGLPAGAGAPSLPDVDLTAVRAANCGGRPDPAH
                     VVTSGRLRVFGHRGVANRHLLAAAAELGREPGRYRDLITHETDLDGAARVMRELARSHD
                     RLIDGRRLVKLSVRIAEHN"
     gene            complement(13810..14820)
                     /locus_tag="JJ691_RS13615"
                     /old_locus_tag="JJ691_27120"
     CDS             complement(13810..14820)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012692.4"
                     /locus_tag="JJ691_RS13615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27120"
                     /product="ROK family protein"
                     /protein_id="WP_211769140.1"
                     /transl_table=11
                     /translation="MLITVLDVGGTHVRWARWSPEQGLGDVRRTSSPSTFRQPGVSVDE
                     SRAVLVRMMAEVVPAGAVAGVSFGAALDHRTRAVYASAPLWGVDSRPFDLVAALRGARP
                     DVRWHVVNDVTAALLHLASTQRARGLRKVWLATISTGVACRVIDQRTGEIPVDGCGLQG
                     EIGHLPATVAVDGLPLDLRCDCGRQGHVAAYASGPGIRRLGEVLRHRRGPVWVASDLAQ
                     ELARGEPFEVALTRAVRSGDTVAVELLAAAAKPIADIVRTSLCLDPELDLVAFTGGVAL
                     GLGEHYLAAVLAHLDRDGLYLTSERKPDWIRDRMAVTEVSGLVGAGIAALSEELT"
     gene            complement(14844..16100)
                     /locus_tag="JJ691_RS13620"
                     /old_locus_tag="JJ691_27130"
     CDS             complement(14844..16100)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF045333.1"
                     /locus_tag="JJ691_RS13620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27130"
                     /product="glycosyltransferase"
                     /protein_id="WP_211769141.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.4e-19,
                     bitscore: 68.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTPVWEVEPGGEGPLHAHVNATATGGGVSELLRGLLRQQPAGWA
                     VIAGNAKFYAVTKYLHHLLHGQSDPARLDDPELMRTYRATLEPQQVWFKERVVQGDVVV
                     LHDPQTLGLAPAIKAAGGRTVWHCHIGAVIEPERGPGAMWRAFGPELEAVDAVVTTLPE
                     FAPPSAHQLFLIPPAIDLEAVKNRELGPDEIAAVLAEIGLTSGREASDVVVVQERPLPP
                     GARVVLQVSRWDPLKDMPGVARCVVGLPSDVHVVLAGTNPLEIPDDPEGLAVLAEVRAV
                     LAELSEVDRSRVHLVNISMKQQDRNALVVNALQRRADVVMQKSLQEGFGLTVTEAMVKA
                     KAVVASDVGGLRQQITHGHNGILVDPADLDDVRAQLCRLLDDPALRREFGDRARATVVE
                     RYTMPQFADAYRKVSEVLS"
     gene            complement(16094..17257)
                     /locus_tag="JJ691_RS13625"
                     /old_locus_tag="JJ691_27140"
     CDS             complement(16094..17257)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012783737.1"
                     /locus_tag="JJ691_RS13625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27140"
                     /product="MFS transporter"
                     /protein_id="WP_211769142.1"
                     /transl_table=11
                     /translation="MLNGVVSGSWAPRVPALAAQIGAGPGVLGLALFGASLGLAASASF
                     AGRMAAQFGARVTVLVSAVVSAGALPLLALVRTPLQLGVVLVLVGASIGSFDVSMNVAA
                     VTVVRRLRRPLMPVFHAGFSFGALAGSLAAALSAGAHADLRLYFALIFVGSVAVTAGVI
                     RFVPAEERVDAAARGRFDRGMLRRPALWLIGGIAFFSAVVEGSNGDWSALFAVRERGMS
                     EAAGALMFSVFCLAMAVVRLFGERVQRRYGPVRILVVGSLLAGVGLLTAAIVPVAWLTY
                     VGYAVAGGGVAFSFPIMAELAGEAGRRGDGTGGAREIGFVTSIAYSGFLLGPPLLGAIA
                     QLTTLSVAVGFVGLIAMLIAPVALASAVARRREETLIVTSSEEAASC"
     gene            complement(17308..18771)
                     /locus_tag="JJ691_RS13630"
                     /old_locus_tag="JJ691_27150"
     CDS             complement(17308..18771)
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012935.4"
                     /locus_tag="JJ691_RS13630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27150"
                     /product="GMC oxidoreductase"
                     /protein_id="WP_211769143.1"
                     /transl_table=11
                     /translation="MTERLRADVVVVGGGTAGCVLAERISKDDRRSVLLLEAGPDYGPH
                     TSGRWPADLLDCRMPARSHDWDPDGPAHASRARVIGGSSVSNACWITVGAPPDYDAWAA
                     YTEGVWNFASTAPFLADAMRELRVREVPAADRGVWHEAVVAGSRSLGLPQVDDVNALDT
                     REGVGWVPLNAVGHTRWHAAFAYLDRARGRTNLQVLAEATAVRLLVRGDRATGVEIVRD
                     GRAETVEADTVVLATGVYGNPALLMRSGIGPESVLCDLGAPVVLPLAGVGENLIDHPKV
                     HLPLTPTAAHLPHDGAYVPQTVLKARSGSATDEYWDLHIVPTSGPAEDERGRFVGPLAV
                     DMYVFVLRPRSRGSVRATSLDPLAPPLIDHRYFTDADRHDRRVALDGVDLVHELAETAP
                     VRELASLTAWSPARRQAVGETPGGYWHPVGTCAMGPENDPAAVTDATGRIHGVSNVYVG
                     DASVMPVIPRANTNLTTVAVAARLAESIR"
     misc_feature    complement(18912..18928)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.53"
                     /tool="antismash"
     gene            19230..20600
                     /locus_tag="JJ691_RS13635"
                     /old_locus_tag="JJ691_27160"
     CDS             19230..20600
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021509.4"
                     /locus_tag="JJ691_RS13635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_27160"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_211769144.1"
                     /transl_table=11
                     /translation="MTVDAALGPGSSTWDRLGQWRYLLVMHRSLVLQAAHPAVGAAVSE
                     FSVYNARPWRRLFRTLESLHTYVYGSAAEQRHELARLDRLHRRMRGTDGYGRAFHAGDT
                     AARAWVHLTIFDAVLTMQRLGGDPLSAAETARFYTEWLRLGQNFGLAADDMPATPEEFH
                     VYFDRMVADTLEDNATVRDLLSGSVYRIPPPPGLPIPTLVWAPLRYAAVTAAVQATIVT
                     LPAVYRERLRLTAPPGADLLVNGAHLAVRLATDLLPTPWRYMPRAAASIRAAAEPTPSH
                     VASTPESFFGRVLDQNGDGVLRWSDMLAMARELSIHFDLEEKDEDTVHMAFRSWWEQLC
                     TATGTATDASVTAAAYSQAIADHRYPGPPDPDHGYGAVAAAVRRLIDRDGNGEILPDEY
                     SRLLDHSPRRAEIIAAMRDLDSDGDGTVQADELEQAFRDFLTGRHDLEAARHLLGRA"
     misc_feature    19271..19285
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     misc_feature    complement(20712..20725)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    complement(20983..20997)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
ORIGIN
        1 cgtcttcgtc ggggacggtg acaggatcgc cgaacagcga aaggacttca tgcgggagac
       61 ctggcggctg gtggacgaac tcggtctggc cggccaggcc gaagtcgcgc acgacccctt
      121 cttcggcaac gaggcgacct cccaacgggc gctggcccaa cggatgatgg aactcaagta
      181 cgagctgcgc ctcccggtcg aaggcgggcg ctcggtcgcc gccggctcgt tcaacctgca
      241 cggcgacaag ttcggctcgg ctttccacat cacgcttccg gacgggtcaa ccgcgcagac
      301 cgcctgcgtc ggcttcggac tcgaacggct cacctacgcg ttcctctcgc agcgcggact
      361 cgacgtggac cgatggccgg cctcggtgcg acagaggctt cagagccgga ttccggcata
      421 gcgaccacac cgaaggagac ctgcatggac ggccacgaat cccgtacgga cgagaaggtc
      481 tgggaactcc tggagcacat atcgatctcg gaccccgaca acgagccgtt cgagaaagcc
      541 gtccagctcg ctccgctgat cgacgacccg gacgagttgc tcgcccaggc ggcacgacac
      601 gcgctggtgc cgagcctggc ggacttcctg gtgcgggccg atttgctccg actggtcccc
      661 caccacgccc agcggcacct gctgggcacg ttgcactgga acaggttcaa gacccgcagg
      721 cacgcgcacg aggcggagcg catcaccacg gtgctcgcaa gcgagggcgt ccgggtggcc
      781 tgcaccaagg gggtggtgtg ccagcaaacc ctttacgacg gccgcggcat tcggcacttc
      841 ggtgacatcg atctgatggt gctgccggag caccgggaga aggcggccga agttctctac
      901 cgcctcggct acgcaggggc cacgaagttc gaccaccgaa cgggcgaact gctggagatc
      961 tcgcgctcgt tgcagctgat gtaccagctc tacccggatc acctgccgca cttcttccgg
     1021 attcccgccg acgacgacgg catgccgtac ttcatggtcg acgtggccta caacctgacg
     1081 tggtacggca gcagctggca gatccccatg gaccgggcac tggacaacgt tgtcggggtc
     1141 gacagcggct ccgtcacgct gcccgcgctg gacgtgccgt acgggttcat cttcgttgtg
     1201 ctgcacctgt tccgcgaggg ctggttcgag cgcaccgtcc gggagaagga cgtccggctc
     1261 ggccagtgcg ccgacgtgtg gcggttctgg gagcgcttcg gccgcgaccg ggtggacgac
     1321 attaggaagg tcctggcgga gtacggcctg gagcccgcca tagcctgggt gtgccgtcac
     1381 gtggacgacg tgtaccgcgg caccatcacc ggtgagctgg ggctcgacga gtactgcgac
     1441 gacggctggc tgcacagcgc gggcgccacg gacggcggct acctggtgtg gcagggcagc
     1501 ctccgcgacc ggctccgcga ccggcggccg cccgtgctcc ggcccggcgg tgaaccgtcc
     1561 ttcgcggcgg cggcccgcgt ttcacccgcc tgaggcggcg cgctcgccgc tgctgttctc
     1621 atcccgacgc cccaggagga tgacatgtca cgcccatatc tccccggcac cgtcaacagc
     1681 catcgggtcc tgttggtgtc cggcttgtgg ccctacgaca ccgtggacga gaagaaggcc
     1741 gtcggccggc tgaacatctt ccacaatcgc gagttgcgcg aagggatcac cgcgctggtc
     1801 ggcgccgact cggtctacga catcgggctg cggggtgcgg acggcggcca gccgctgttc
     1861 cgtccgaaca cggtgtcgga gccgactctg gtgtcggtgg cgctgaggtc actgctgccc
     1921 gacgacgtgc acgtcaccga tcaggaactg gccgatctgc tgcactccga cggccggtcg
     1981 gaggaggact tgagggccgc cgcgcgagac gccgtgtgcc tgttgtcaac cagctatgtg
     2041 acgaacttcc cggacctgcg caaggtcgtc gacaagctgc gggagctgtc ggtcggatac
     2101 gtcgtcgcgg gcggctatct ggcgacccgc aaccctgacg ccgtcctcga ctgcggcgtg
     2161 gacgccgttg tcgtcggcga cgcggaggac tcgatcgccg cgctgctgcg gtgcctgcgc
     2221 ggtggggacg actggagcag cgtgccgaat ctctggtacg ggaccgagga cggcggcaag
     2281 gcctacacct tcgaccgcct ggtcgcgctg gacagcattc ccgtcaccat gccggacggc
     2341 gacctgtcgg ggatctccgt gccgtacgag tcgatgcgcg gttgcccgta caagtgcgcg
     2401 ttctgctcct acccgctggt gaccaccaaa tggcggttca agagcgctga gaagctgctg
     2461 gcggactggc aggccatcga gcgcagcggc gccaaggaga tcatcgcgct ggactcgacg
     2521 ttcacgatcc cgccgaagcg tctgcgagac ttcctcgatc tctaccacga ggctggcctg
     2581 accatcccgt ggggcgcgta ctccagggtc acgccgttac gcaacgagga gacggtgatc
     2641 cagctgaagc gggccaacaa ccgctggctg tccatcggtt tcgagagcgg cagccagcac
     2701 atgctcgacc tgatgaacaa gggcacccgg ctcaaggacg cctatccggc gctggcccac
     2761 ctgcgcaagc accgagtcgc gccgtggtcg aacttcatca tcgggtaccc gggcgagacc
     2821 gaagagactg tcgatgcgac cacaaccttc atgtccgaac acatcttcgg tttctacggc
     2881 atctacgtct tcaacatccg cgaccgagcc atgccggtgc tcagcgatcc gggtgccaac
     2941 gtccactggg aggacgtggg cagcgactgg acgcattcca ccatgaacag cgaccaggcc
     3001 accgaactgc gttggcggac ttacgtccgg gtctgtctgg cgaaccccga cgcgatcaac
     3061 gtcgacgtct tccgcggcag caacgtcgag aaggagtacg gggtctggga ccgggcattc
     3121 agcgcgctca agcacatcga ggcgtgggcg ctgcgctgga tcgaccccac gaccgtggcg
     3181 gctgagggcg gggacgacat cgcggggtcc gaacgggcgc tgcgcgacct gctcgccccg
     3241 ctcggctgaa cggaggattc ttgcccatca tcgagaaccg ccccgtcggc gtgctcgccg
     3301 gaggccgggg cgtgctgcag ggctcgtcag aagtggtcgc cgggcgcgtc aagacgctgc
     3361 tggagtcggc cgacatcgct gccgctgtgt tccagtacgg cagcgaggag ttcgccgccg
     3421 cgctcgcccg cggggacctg cgcctgctcc aggacgtcac ctacggcgtc tacggccggg
     3481 ccgagtcgct ggccgccgcg gccggcctcg gcttcgtcgg gaccggggca cgacaggcag
     3541 aggtctacga caaagtgcgg ctgaagacct ttctctcgcg aagccgggtg cgcacgccgg
     3601 cccatgttgt gctcgacgcc cacgcgcagc cgtccagctg gtcggctatc agcctgctgg
     3661 cgggcccgat cgtggtgaag ccggccaccg cggacctgct cagcgcgggc gtgcggttct
     3721 tcgacgccgc ggacccgtgg cagccagagc tgcgcgagca catcgggcag ctgttcgccc
     3781 tcgaccagac cgttctggtg gagcgctatg ttccagggct ggagatctgt ctcggctacg
     3841 aggtgtcgcg ccgggggttc gagatgtacc ggccgctcac cataacgaag gaagccctgc
     3901 tcttcgacca ctcggtcaag acgtccaagc ggtacgcgtt cacaccggtc gacgttcccg
     3961 cgtcggcgct gcgccaactg agtcggctcg ggcggacgat ggcggcggag ttcgacctca
     4021 ccgggtgctt ctacgtgaac gcgatcgtgg cggacgacgg cgacgtgtcg gtgttcgacg
     4081 ccggtgcgac agtcggcctg acggagcaca gctacttccc agccgcggct gccttgcggg
     4141 gcgatgcgct cgacgacctc ctcgtccggc agttcgtcga accggttgag gatctgttgc
     4201 gccgggaaag cgccacgcaa cgcgagccgg ccgagatgga gacacgctga gtggacgcct
     4261 ggctggacgg cgagactgtc gccgaggaat cagtgaccct gcacgtcaac agtgtgacgg
     4321 cggcgctcgg aacggcgttc ttcgaggcga tgcgctgcta cccagtgtcc agacgcggcg
     4381 ccgcggtgtt ccgctttgag gcgcactacc gccggcttgt ccgctcgctc tccgtggtgg
     4441 gggcccggct tccgctcacc gccgaggatc tgctgtccgc ggtcgcggag atcgtaagcg
     4501 cgaactcggc cgcaggtcag gcctgctaca tcaaggtgat ggtcttctgg gacaccgtac
     4561 tcagcggcac ttccctcgtc gacctcggcg agttcacacc aagggtcgcg gtgttccttc
     4621 gcacgacacc ggactccttc ttccataact gcccgcggct gcgctgccgg atctcgtcgt
     4681 ggcgccgtat ggacgacaac gccatgccag cccaggccaa agcgaccgcg aactactaca
     4741 acgcgcgcct cggcctgacc gaggcgctcg ccgccggcta cgacaacgcg atcttcctca
     4801 acggccgcgg cgcggtcaca gaggcggcgg aggccaacgt gttcgtcgtc gaccggcgcg
     4861 ccatgacggt cgccacgccc tcgctcgaca gcggggtgct gcctggtgtg atccgtgact
     4921 ccgtcctgga ggtgctgcgc ggcgacgccc gcttccaggt ctgcgaggag cggctccatc
     4981 cgatggacct ctacgcggcg gacgaggtct tcctgaccaa taccgcccaa ctcgtcaggc
     5041 aggtcagcga gatcgacgga cggcagttgg ccaccggccc cggcactctc gccggtgacc
     5101 tccgagccga actcgtcgac atcctgttcc ggcccgaccg gcgcccggag tggttcgcag
     5161 cacttcccat ctagccccat ggagcacaca tgcatcggac ggcccaacag aacgacgtgc
     5221 tcatcgacgg tctcacccgc cgtttcgagc gccagaaacc tgccgtggac tacatggcgg
     5281 agcacttcgg cgtcggaccg gtggcggact tcggctgcgg caacggcatc ccgctcgcct
     5341 accaggcaga ccgacacccg gacctgttct tcgtgggagt cgaccacagc accgacatcc
     5401 tcaaccgcaa cctcgcgcgg gaccgcgcca acgtgctgct cgtcaccgcc gatttggcaa
     5461 gtcggacgtt ccccgacgac agcctgggaa gcgccgtctt caatcgctca ctacacgagg
     5521 tgtactccct ttttggcgag gcagggctga agcaggccgt gaccgcggcg cgcaacgcgc
     5581 ttcaccccgg cggacgcgtg ttggtgtacg agaacgcggt ccccagccgg gaccgggtcg
     5641 ccctgcgcat cgtcacggac gaggtgcgcg agctgttcac ccgcttcatc cgcgactact
     5701 ccgtccgccc ggtgccctgg acgcagaaga ccccggacac cgtcgtcctc caagaggacg
     5761 acgcgctgga gttcctcacc aaatatcgcg accccgactg ggagtcggag atgcgcgagg
     5821 tgcacttcct ctactcgctg gaggagtggg acgcggtcct tgcctcctgc ggtctggaaa
     5881 aagtggctgt ccggcgtttc gacgatcgcc agatcctcgc cacggacggc gtggaacccg
     5941 gctgggaaat cgccgacttc aagcatgtcc tggtctaccg gcggccggcg tgacaacggc
     6001 gacagcagcc gcccgcgagg cctgggacct gattcgccag cgagacaagg cacggcagat
     6061 ccgcgaacag acgctgcggc tgtcccaggg acggccgcat catcttggtg gccagctgtc
     6121 ctgtgtggag atcctggtgt ccatcttcta cggtcacgcg cccacgctcc ccgacaccag
     6181 attcgtgttg tccaaggggc acgcgtgcat cacgttgtac gcgatactcg ccgacctggg
     6241 tctcattccg gcggaggagc tggagacgat catggaggcg ggagggcggc tgctggggca
     6301 cccgtgccgg accacgacgc ccgcggtgga cgcttcgacc gggtcgctgg gcatggggct
     6361 gtcgatggcg gcggggatgg cgcttgccgc acggaccact gggcgcgaga cgcacgtgca
     6421 cgctttgctg ggcgacggtg aaatgcagtc cgggcaggtg tgggaggccc tgatgctgat
     6481 gggtcaccat caactcgaca ccgtgcacac cgtcatcgac tgcaacggcg cgcaggccga
     6541 cggcgacacc gccgacatca tcggcctcga accgctcccg gcgcggctgg aggcgatggg
     6601 cctggaagct gtcgaatgcg atgggcacga cctggcagca ctcaacgaag cgctcgccga
     6661 accccgccgg ggccggcccc gcgtaatcgt cgcccggacc gtcaagggca agagcgttcc
     6721 gatgatggaa ggtgacaacc gctggcacag cggcgccctg tccagggacc agctcgcgaa
     6781 tgcgctcgcc tctctctact gaacggagca cggtgaagag gttctccagg ctactgctcg
     6841 acacgatgga gacggactcc cgagtcgtcg tgctggacgc cgacctgtcg cgcagcagcg
     6901 gatcggccgc ggtggctgac agatggccgg accgcttcgt gaacacgggg atcgccgagc
     6961 agaacaccat gggcgtcgcc gccgggatgg cgctgctcgg gctgcgcccg atcgtgcaca
     7021 cgttcgcggc gttcgcaacg atgcgggcct gcgaacagat ccgcacgtcg atcgcctacc
     7081 aacagctgaa cgtcaccatc tgcgcgagca agggaggtct cgccgcgtcg cgttcgggtc
     7141 cgacccacca cgcgaccgag gacctcgcca tcatgcgggc aattcccggc atgaccgtgc
     7201 tggcgccccg cgacttccgc gacctgaccg cgtcgttccc ggaggtgctg gaccttccgg
     7261 gaccggtgta catccggatg ccgcccgagc aggagcctga cgacctgacg ggctccgtgc
     7321 cgtccatcgg cgcgggtgtt gtgctccaga agggagccga cgtcgtgctc gccttcaccg
     7381 gtagcatgac gaggacggta cgccagtccg ccgagcgcct cagcgccaag gggcttgacg
     7441 tcggcatcat ctacctgccg tccgtaaagc ccctcgacga cggcctcatc gagcaatgcg
     7501 ccaggacggc tcggctggtg gtcaccgtcg aggagcacaa cgtcatcggc ggcctgggat
     7561 cagcggtggc cgaagtgctg tcagcccgcc gatcggcgcc gctgctgcgg ctgggggtcg
     7621 aggatcgttt ctgctacgcg tcgggcaccc acgaggagat gctcgacgcc tactgtgtgt
     7681 cggtcgaaga acttgtccag caggtcatgg agcgttgtta gatgagtccc gaatcctcac
     7741 aacgggcagc cgacagcgtc cgcacccaac tcgcggacct ggtcgggatg taccccgagc
     7801 tcgccacatt ccaccagacg gtcgtcgggc ggcttcccga cacatgcctg gagttgctgc
     7861 cgcgtacggc gctggtcgtc gtccctccgg acggactgat gcagggagtg caccggcggc
     7921 tgctcgacga acacggcgaa cacgtggtgg ctttccggtt ccgcgttctg agccagcgtc
     7981 ttgccgagcg cctctacctg gacggtctcg tgacgcgggc gccggggcgc cacattcggt
     8041 cgtggtggat caagagcaag ctcttcgacc tcggagaggc gctggtcctc ctcatgcgac
     8101 acccgacgga ccccgggttc caggcgaccg tcacggcgtt gaagggcgcc tccgatccga
     8161 tgctcgcgaa gccaggcacg tatcgggagc actaccggac cccgaacaag accttcggcc
     8221 tcctgcacag ctccgacgac ctgctgagca tgttgtacga ggcgaacgtc ctgttcgaac
     8281 ccgagggcct cacccagttg ttgaccaagc cgtgctggga ccccgcacac cgggccctcg
     8341 tgtccggcta cgaaggtgga gtgagcgtac gcaggatcga gtcctaccgc gtgctctacc
     8401 ggctgaagcg gcggctgctg gccgaaccga cggcggcggg agtgttgcca gtgtcgctgc
     8461 tcgaagcggt cgaggagaac taccggaccg ccctcgacgt ggtcgccgcc gaccctgggc
     8521 atatcgcgga gacggtgacg gttgctcggc ttctcgtgga ggagcgcgga ctgctcgacg
     8581 gcatccaccc gcacgccggc gttttggcgg ccccccagga agaggacctc cgagtggcgg
     8641 gcgccgagga acagcgcgtg cgggtcaaga ccgcgctggc ctgcttgcgg acgctgaccg
     8701 agccgactgc tcttcgcacg gccggtttcg agagcctgga gtcctcgctg gaggccctcg
     8761 gcatcccgct gaccgcgctg gaacgcaccg tcttagaaag cctcttcttc ttctacgcga
     8821 ccgatccgcc gcgagccaca gtgacgacat cagccggtgc agccagaagg agcgcagcca
     8881 tgcccaacgc ttaccaacag gtgctcgacg ccgccgagaa gcttgaggat tacccgcttt
     8941 ccccttctga tgtggcggag ctgggtcgga cgggtctgga agcgaccgca ggccgattgg
     9001 ccttcatgat cgtcacgccc gacgccgtgc accgtggcct gcacgcggac accctgacca
     9061 aggtgcacaa cgccggcttc cgcgtcctcg cgcaccagac cagaaatctg cgcgacagcg
     9121 acatcgagga actctacaag gacgggctgc gcgccaagat cctggaaaac cggcgaacgc
     9181 actggtatct gacccgtaaa gggctgggct tcggcacctc tctcggccta ctcctccatc
     9241 accccgacgg cgacgcgtgc gagcggctgc tgcggctgaa gggcgcctcg aagccggccg
     9301 aagcgacgcc cgactcggtc cgtggctcac tgggcagcta ctcgaagatc ctggcactga
     9361 tgcacagctc ggacactccc ccggccgtgc tgcgcgagtg ccttctgtac ttcaccgccg
     9421 agcaggtccg cggcgcgctc tctcaactcg ccgaacaccc cacgccgcag gggaccccga
     9481 tctctctgct ggttgaggcg ctctccccga ccacctcgta cgacgacccg ttcacggtcc
     9541 tgtacgcgct gaagatccgg atctcccacg ccctcgcggc acacccgctg accggcgccg
     9601 aactccagcc catgctggaa cagcacctga gcggcctgcg cgccatgcgt gcgacgctga
     9661 gcgcggatcg agtcccttgg ccgtctcgaa cggctgccgt gggccacgaa ctcgagcggg
     9721 agcacaagct gctcgtcgag ggcgcgctcg cccagagccc gcagtcggcc ccgggcgagt
     9781 cgctcgaacg gctggcctgg caccggctgg ccctcaccgc ccggcagctg gccgaccaac
     9841 agggcttcgg acagctcgac atggaccagg tgagggcggc gctccatgcc gcgcacgtcc
     9901 acctgacctc atgggaggcg ttgctcgtgg agaacctggt cttcttctgg gagccgtgac
     9961 ttggccaccg acttcggtgc tcagtggacg tagtcctcga ctacaccacg aaggccgggc
    10021 ccgcgcacag atcgcgatgc atggcgacga cagcttcgat ctctgcctcg gtgacgtcat
    10081 tgacgaacgt gacgtcaccg atcccgaccg gcaggggcag ccgctgctgg ccgtcgcgat
    10141 gccggaccgt gtcctcaagc gcgtgcacca gcaggtcgtg tttgatcacc ggatgccaga
    10201 ccggcaactc cagcgcggac atcaccgcga ggacacggtc cctttcgacc cgggtcaaca
    10261 ggcctcgccg gtatgccatg accgtggtca acgccatgtc cacacatacc gcctccccgt
    10321 gcagcatcgc cggcagcgcc cgcatctcca cctcgggact gaacgtgtgt ccgtagtcga
    10381 cgcgacgctc caactcggct tcccagagat tcgggtgcag ttcctcgagc atgccctgga
    10441 tggcggcgtg cagcacggtg accgccgccc ggtcaccgac cggcgtgcgg ccctggagct
    10501 tctcgtccag cagcagccga ccgtgcacct ccagcagttc gaacagccgg aagtccttca
    10561 ccagtgcgat cttcagaatc tccgcgatgc cgttggcgat gttccttcga tccactgtgg
    10621 acaggaaggt gcggtccagc agggtgaggt cggcggccat gtaggtgcca agtctgttct
    10681 tgtgaccgtt gaagttcacg ccggtcttga ccccgacgcc ggcgtccacg aacccgacga
    10741 gcgtggtcgg cacgcgaatg aacggggtgc cacgccggta cagactcgcg accaggccga
    10801 cgacgtccat cagcacaccg ccgcccacga cgaccactgg ttcccgccgc cgggcgatgc
    10861 cgaagcaatc gagttcctcg gcgatcctct cggcggtagc caagtccttg acggtctcgt
    10921 cggcccgcac caccactacc gcgtgatcca cgccgtggtg ctcgaagtag gcgcgaatcg
    10981 cctcgccgta cagcagatcc acgttgctgt cgaccacaac gaaccgtcgg caccgcgcat
    11041 ctcgccccga accgatctcc aacaggtcgg tgtgctcagg ccgaaacagg ccgtcctggc
    11101 accgcacctc gtagctgacc tccctctggg cgcgcacacg ccaggtcccc tcgcggtcga
    11161 agtgcagtcc gctccgctcg ttcaccgtcc agccccccga atcgaatgtc gcgcggggaa
    11221 cagttccgca cgtcggcgcg cccacgcgag atcggcggcc aaccggacgg aatccccgtc
    11281 gcggtagtcg ttctccagca cgaacgcgtg caccggcgcc tgatgtcggc gcagtgcgtc
    11341 cactgtctcg tcgagcttcc cgatccccga gccgagcagc ggcgatgcgc cgacggtcgg
    11401 cggcccgtcc ttgaggtgca cctgatcggc cagtaggtcg ctcgccaacg ccaccagctc
    11461 ggcgacgcac cggccggtcg ccaccgggtt gaacgtatcc agcaccagcc ggaacgccgg
    11521 cgagtcgatc tcctcggcga gcgcgcgagc ccgttcaccg tcgagcacgt tctcgtttgc
    11581 cagcaacaca tgccgcgctg cggcctccgc cgaggcccac cgcaggacct cggccgttcg
    11641 ggtgaacgac tccagcccgt cgatcgcgct acggcgaaag ctgggcacga acaccagtgg
    11701 cacgcccagc tcgaccgcgg cgtccagcaa ccggatcagc agtggacgca cgatctccga
    11761 ctccgcggtc aagccgacgt cgttgaactg gttgccggcc aaggcaagca agtccacgcc
    11821 acactcggcc gccgcggcac gcaacgcctc gatccggccc ggcccgtcaa tcggctcgcc
    11881 gcgtcccggc ccgccgaagt cgagttgcac gccgtccgcg ccgaccagag cagccagtcg
    11941 gacggcttcc ggcccggacg ccgccaggcg ccactcggtc agcccgacct tgcagctcac
    12001 ggcagcgttc ggctctgcga aacgggtaag ccgccgcggg ccgatctcca ctcgccgttg
    12061 ccgtcgacca caagactgtc cccatggtgg ccctcgcccc cactcagcgc cagctcgacc
    12121 gccacccgtc cgaacgccga cggtgccatg tagccgctgt agtcgaagtc tggcggtcgg
    12181 cgccggcgga tgccggggct gtccaccatg ccggccggca gcacctgcac cactcggaca
    12241 tggctctcct cctgggtcaa cgaatccagc agtgacttgg ccgcggcctt ggaagccgcg
    12301 tagcccgaac ggcccggtcc gccgttgaac gccacttcgg acgagacccc gacgaacaac
    12361 cccgattgcg cccggcgcag ggccgggagc agcgcccgca gcgtgagcca gagcccggtc
    12421 acgttgacct ccaactgcgt gtgccattcc acctcggaca cctcgctgaa tctggcgcgc
    12481 ttgtctccgt agtgcacggc cgagaagcaa gcggcgtcca cccgccccgt gctcagtccg
    12541 accagccgct cacgggcgtg atcgggctcg gagaggtcga gccggaccca gctcaggccc
    12601 gggccgactg caggccgcct gcggctgcac accacgacct ccgcgcccgc gccagcccac
    12661 gcgtcggcga tgccgcggcc gatcccggtc gagccgccta cgacgatcat gcgccgtccg
    12721 gtcagcgagc ccatcagttg tgctccgcga ttcgcaccga cagcttgacc agccgtcgcc
    12781 cgtcgatgag gcggtcatgc gaccgggcca gttcccgcat cacccgcgcg gcgccgtcga
    12841 ggtcggtctc gtgtgtgatc agatcccgat aacggccggg ctcgcggccc agttcggccg
    12901 ccgccgccag aagatgccgg tttgccactc ctcggtgacc gaacacccgc agccgccccg
    12961 acgtcacgac gtgcgcggga tccggccggc caccgcagtt cgccgcccgg acggcggtga
    13021 gatcgacatc cggcaacgac ggggcgcccg caccagctgg aaggccgccg acgatgtcga
    13081 tcacctcggc cccggccgcg atcgccacct ccaacgccgg cacggtcgca tcgcgcggtg
    13141 tggccaccag cgcggcggtc gggccgtcca acgcgacttc ggccagatcc gtcagcaact
    13201 cgtcggccga gtgcgggccg gccccgctga acaccaaccc cgcctcagag ttgtgcagga
    13261 ggactacccg aacgtccgcg cccagccagc accgcgaggc ccgcaccgcg atatgtccga
    13321 tggtcccgtc gcccacgacg agcagcgtcg ccatggcgaa tctcctcagc tcgcccaacg
    13381 cgtagcgcac caccgccagc ggctccagca gcggcgccag cgtgacatca gtcgtcgccg
    13441 gcagcggaat caccagtcca ccggtcacag ccggcgcggg caccagcgtc cgctcctgaa
    13501 acaggccatc cacgttgtgc cccaacagga acgacggatc ggccgggtgt gtcgggttga
    13561 ccgtgacgag cgtgcccggc gccagttcgt ccgacacacc cgcaccggcg gccgccaccc
    13621 tcgccacgcc ctcgtggccg atcaccggcg ctgggtcgtc ccgcaagccc cgcagcatct
    13681 ggatgtccgt gccacacagg cccgcgtaca ggggcgcgat gctgagctcc cccggtcccg
    13741 gaacgacagt cggtcgcagt tcgaccgacg tcgtgcccat cccgcgcacg atcgcccggt
    13801 gtcggccggt cacgtcagtt cctcggacag tgcggcgatc cccgcgccga caagtccact
    13861 cacctcggtc acggccatcc ggtcgcgaat ccagtccggc ttccgctcac tcgtcaggta
    13921 caggccgtca cggtcgagat gggcgagcac cgcggcgagg tagtgctcgc ccaggcccaa
    13981 cgccacgcca ccggtgaagg cgacaaggtc caactcggga tcgaggcaca gcgacgtccg
    14041 cacgatgtcg gcgatcggct tggccgcagc cgccagcaat tcgacggcga cggtgtcgcc
    14101 ggacctcacc gcccgggtca gcgccacttc gaacggctca ccccgggcca gttcctgggc
    14161 gagatccgac gctacccaga ccgggccccg ccggtgccgg aggacctcgc cgagccggcg
    14221 gatgccgggc cctgacgcgt aggcagcgac atggccctgc cggccgcagt cgcagcgcag
    14281 gtccaacggc aggccgtcga ccgccaccgt cgccggcaga tggccgatct ccccttgaag
    14341 tccgcagccg tcaacgggaa tctcgccggt gcgctggtcg atcacgcgac aggcgacacc
    14401 ggtgctgatc gtggccagcc acactttgcg cagaccccgg gcgcgttgcg tgctggccag
    14461 gtgcagcagc gcggccgtga cgtcgttgac gacgtgccag cgcacgtcag gccgggcgcc
    14521 ccgcagtgcg gcgaccagat cgaacggccg gctgtcgacg ccccacagcg gcgcggaggc
    14581 gtagacggca cgcgtgcggt ggtccagcgc ggcgccgaag gacacgccgg caactgcgcc
    14641 cgccggcacc acttcggcca tcatccgcac cagcacggcc cgcgactcgt cgaccgacac
    14701 gcccggctgg cggaaagtgc tcggcgacga cgtccgccgc acgtcgccga gcccctgctc
    14761 cggcgaccac cgtgcccagc ggacatgtgt gccgccgacg tccagaaccg tgatcagcaa
    14821 agttccccct cactgcagcc gattcagctg aggacctcgg acaccttccg gtaggcgtcg
    14881 gcgaactgcg gcatcgtgta gcgctccacc accgtggccc gcgccctgtc gccgaactcg
    14941 cgccgcaggg cgggatcgtc gagcaggcgg cacagctggg cccggacgtc gtcgaggtca
    15001 gcagggtcga cgagaatccc gttgtgccca tgggtgatct gctgacgcag tccgcccaca
    15061 tcggaggcga ccaccgcctt cgccttgacc atagcctcgg tcaccgtgag gccgaacccc
    15121 tcctggaggc tcttctgcat cacgacgtcg gcccggcgct gcaaggcgtt caccaccaac
    15181 gcgttgcgat cctgctgctt catggagata ttcaccaggt gcacccgcga acggtccact
    15241 tcggacagtt cagccagcac ggcgcggacc tcggccaaca cggccaagcc ctcgggatcg
    15301 tccgggatct cgaggggatt ggtcccggcc agcaccacgt gcacgtccga cggcaggccg
    15361 accacgcagc gggccacgcc gggcatgtcc ttgagcggat cccaccgcga cacctggagc
    15421 accactcgcg cgcccggcgg cagcggccgt tcctggacaa ccaccacgtc cgacgcctcc
    15481 cggccactgg tgaggccgat ctcggccagc accgccgcga tctcgtccgg gccgagctcg
    15541 cggttcttca ccgcctccag gtcgatcgcc ggcgggatca ggaacaactg gtgggcgctc
    15601 ggcggcgcga actccggcaa cgtggtgacc acggcgtcca ccgcctcgag ttcggggccg
    15661 aacgcccgcc acatcgcccc cggcccgcgc tccggctcga tcaccgcccc gatgtggcag
    15721 tgccacaccg tccgtccacc ggctgctttg atcgccgggg ccaggccgag cgtctgcggg
    15781 tcgtgcagca ccaccacatc cccctggacg acgcgctcct tgaaccacac ctgctggggt
    15841 tcgagcgtgg cccgataggt ccgcatcagc tccgggtcat cgagccgtgc cgggtcggac
    15901 tgcccgtgca gcaagtgatg caggtacttg gtcacggcgt agaacttcgc gttgccggcg
    15961 atcaccgccc agccagccgg ctgctgccgc aacaacccgc gcagcagctc cgaaaccccg
    16021 ccgccggtgg ccgtcgcgtt cacatgcgcg tgcagcggcc cctcgccgcc gggttcgact
    16081 tcccagaccg gtgtcagcat gatgccgcct cctccgacga cgtgacgatc agggtttcct
    16141 cacgcctgcg ggccacggcc gacgccagcg ccaccggcgc gatgagcatg gcgatcaggc
    16201 cgacgaagcc cacggccacc gacagggtcg tcagctgcgc gatggcgccg agcagcggcg
    16261 gtccgagcag gaagccggag tacgcgatgc tcgtgacgaa cccgatctcc cgcgcgccgc
    16321 cagtgccgtc gccacgtcgg cccgcctccc ccgcgagttc ggccatgatc gggaaggaga
    16381 acgcgacccc gccgccggcg acggcgtagc ccacgtaggt cagccacgcg accggcacta
    16441 tcgcggccgt cagcaggccg accccggcca acagcgaccc gaccaccagg atccggacgg
    16501 gcccgtagcg gcgctggacg cgttcgccga acagccgcac caccgccatg gccaggcaga
    16561 acacggagaa catcagtgcg cccgcggctt cggacatgcc ccgctcacgc acggcgaaca
    16621 gcgcggacca gtcgccgttg gaaccctcga cgaccgcgga gaagaacgcg atgccgccga
    16681 tcagccacag cgccggccga cgcagcatgc cgcgatcgaa ccgaccacgc gcggcggcgt
    16741 cgacccgctc ctcggcgggc acgaaccgga tcacgccggc cgtcacggcg acggagccga
    16801 cgaaaatcag ggcgaagtac agcctgaggt ccgcgtgggc accggcggac agcgcggcag
    16861 caagagaacc ggccagcgcg ccgaagctga acccggcgtg gaagaccggc atcagcggtc
    16921 gccgcaggcg acggacgacg gtcaccgcgg cgacgttcat cgacacgtcg aacgatccga
    16981 tggatgcgcc caccaacacc agcacgaccc ccaactgcag cggtgtccgc accagcgcga
    17041 gcagaggcag ggcaccggcc gacaccacgg ctgacaccag caccgtgaca cgggcgccga
    17101 actgggcggc catccggccc gcgaacgacg ccgacgcggc caggccgaga ctggcgccga
    17161 acagagcgag ccccagcaca cccgggccgg cgccgatctg cgcggccagc gccggcacac
    17221 ggggcgccca cgaacccgac acgacgccat tgagcatgaa cacgacgaaa acaggaacct
    17281 gccccgaccg ttgcccccgc gaacggatca ccggatcgac tccgccagcc gggcggcgac
    17341 cgcgaccgtg gtcagattgg tgttggcccg tggaatcacc ggcatcaccg aagcgtcccc
    17401 cacgtacaca ttggacacac cgtggatccg cccggtggcg tcggtgacag cggcggggtc
    17461 gttctccggg cccatcgcgc aggtgccgac cggatgccag tacccgcccg gtgtctcacc
    17521 gaccgcctgc cgccgggccg gtgaccaggc ggtgagactg gccagctcac ggaccggcgc
    17581 tgtctcggcg agctcgtgga cgaggtcgac gccgtcgagc gccacccgcc ggtcgtggcg
    17641 gtccgcatcg gtgaagtagc gatggtcgat cagcggcggt gccagcggat ccagtgacgt
    17701 cgccctgaca gagccacggg accgcggcct cagcacgaac acgtacatgt cgaccgccaa
    17761 cgggccgacg aaccgtccac gctcgtcctc ggccggcccc gaggtgggca cgatgtgcag
    17821 atcccagtac tcgtcggtgg ccgagccgga ccgagccttg agcacagtct gcggcacgta
    17881 ggcgccgtcg tgcggcaggt gcgctgcggt cggtgtcagc gggaggtgca ccttcgggtg
    17941 gtcgatgagg ttctccccca ccccggccag cggcagcacc accggtgcgc caaggtcgca
    18001 cagcaccgac tccggcccga ttccgctacg catcagcagt gccggattgc cgtagacgcc
    18061 ggtcgcgagc acgaccgtgt cggcttcgac cgtctcggcc cgtccgtccc ggacgatctc
    18121 gacgccggtg gcccgatcac cgcggacgag cagccggacc gccgtcgctt cggcgagcac
    18181 ctggaggttc gtccgcccac gagcccgatc gaggtaggcg aatgccgcgt gccaccgtgt
    18241 gtggccgacc gcgttgagcg gcacccagcc cactccttca cgcgtgtcga gggcattgac
    18301 gtcatcgacc tgcggcaggc caaggctcct ggacccggcc acaaccgcct cgtgccagac
    18361 gcctcggtcg gccgccggga cttctcgcac ccgcagctca cgcatggcat cggccaggaa
    18421 gggcgctgta gaagcgaaat tccagacacc ctcggtgtag gcggcccacg cgtcgtagtc
    18481 gggaggcgcg cccacggtga tccaacaggc gttgctcacc gaggagccgc cgatcacccg
    18541 cgcgcgcgag gcgtgcgcgg gaccgtctgg atcccagtcg tggcttcgtg ccggcattcg
    18601 gcagtccagc aggtcagccg gccatcgacc gctcgtgtgg ggaccgtagt ccgggcccgc
    18661 ctccagcagc agcaccgagc gccggtcgtc cttgctgatc cgttcggcca gcacacaccc
    18721 ggccgttccg ccgccgacca caaccacatc tgcccgcagt cgctctgtca tcaactctcc
    18781 gtccacctcg gactgaaccg atcggacggg ggcacgcgat aaatggatcc tgcccaccac
    18841 cgcgagaagc tcgccggagc ccctgtgaca actcccccca ctgccgccga atgtacaact
    18901 cttgcataga cctgtaaaga agttgcgaaa ctgctgcgca acggtcaccg catgacctgg
    18961 agcgcactcc atcaacggag gcttcgtgca cgcctgaaac agctctggat tcagactgcg
    19021 ctcggccgtg ccggtccacg acaaccccac ataaccggcc attagctccg accccgaccc
    19081 acagcggccc ggcaggatcc gtcctgccgg gccgctgtgc ggcaagcggg ggaatccgct
    19141 acctcattcg gtgatttcca cagcggagcg tgttctccgc tacccggcgt cacagctaac
    19201 ttcggcccga actggcgcgg aggtggcgaa tgacggtcga cgcggcactg ggacccggct
    19261 ccagcacctg ggaccgcctc ggacagtggc ggtacctgct ggtgatgcac cgctccctgg
    19321 tcctccaagc agcgcacccg gccgtgggcg cggccgtcag cgaattctcg gtctacaacg
    19381 cccgtccctg gcgaagactg ttccgcaccc tggaaagcct ccacacctac gtctacggca
    19441 gcgccgccga acagcgccac gaactggccc gcctcgaccg cctgcaccga cggatgcggg
    19501 gcaccgacgg ctacggccga gccttccacg ccggcgacac cgccgcccga gcctgggtgc
    19561 acctgaccat cttcgacgcc gtgctcacca tgcagcgcct cggcggcgac ccgctgtccg
    19621 cagcggagac ggcacgcttc tacaccgagt ggctccggct cggacagaac ttcggcctgg
    19681 ccgcggacga catgccggcc acacccgagg agttccacgt ctacttcgac cgcatggtcg
    19741 ccgacaccct cgaagacaac gcgaccgtcc gcgacctgct gtcaggcagc gtctaccgca
    19801 tcccgccgcc acccggcctg ccgatcccca cgctggtctg ggcgccactg cgctacgcgg
    19861 ccgtcaccgc cgccgtccag gccacgatcg tcacgctgcc cgccgtctac cgcgaacgcc
    19921 tccgcctgac cgccccgccc ggcgcggatc tgctggtcaa cggcgcgcac ctggctgtac
    19981 ggctggccac cgacctgctt cccacgccct ggcggtacat gccccgcgcc gcagcgtcga
    20041 tcagggccgc cgccgaaccc acgccgtccc acgtcgcctc cacccccgag tcgttcttcg
    20101 gccgcgtact ggaccagaac ggcgacggcg tgctgcgctg gagcgacatg ctggcaatgg
    20161 cccgcgagct cagcatccac ttcgacctcg aagaaaagga cgaagacacc gtccacatgg
    20221 cgttccggtc ctggtgggag cagttgtgca cggccaccgg caccgccacg gacgcctccg
    20281 tgaccgccgc cgcctacagc caggcgatag ccgaccaccg ctaccccggt ccgcctgacc
    20341 ccgaccacgg ctacggcgcg gtggcggccg cggtccgacg gctgatcgac cgtgacggca
    20401 acggcgaaat cctcccggac gagtactccc ggctcctcga ccacagcccg cgccgcgcgg
    20461 agatcatcgc cgccatgcgg gacctcgaca gcgacggcga cggcaccgtc caggccgacg
    20521 agctggagca agccttccgg gacttcctca ccggccgcca cgacctggaa gccgcccgcc
    20581 acctgctcgg ccgcgcctga caccaccaag cctgccctgc ccggtccttc ccatcctgcc
    20641 gcccactcct gccctgcctc ccctcccgtc ctacccgtcc tgttgaaaac gcgttttcga
    20701 caacgtatag tcgaaagtac gttttcgata agacgggcag gcggcatgac caagcaggac
    20761 gacaccccct cacggcgcag gcgactcacc cccgaacgcg agcgggagat cctcgaaacc
    20821 accttcgacc tggtgtcgga ggtcggctac gacaacgcca ccgtcgacga ggtcgcccga
    20881 cgcgccaagg ccagcaccgc cacgctctac cggcagtggg agagcaaacc caagctcgtg
    20941 atcatggccc tgatggcccg caagtacccg cccgtgccgc cgatcgacac cggtgacctg
    21001 cgcaccgacc tggtcacgct ggcgcgcagc atgccgccac cccaccccgc cggcaccccg
    21061 accctcggca tctggcaggc cgtcatggcc gacccggcgc tggcccgggc gctgcgtgac
    21121 gtgctgttcg ccccgta
//
