LOCUS       NZ_CP073318            22584 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Kutzneria sp. CA-103260 chromosome, complete genome.
ACCESSION   NZ_CP073318
VERSION     NZ_CP073318.1
KEYWORDS    RefSeq.
SOURCE      Kutzneria sp. CA-103260
  ORGANISM  Kutzneria sp. CA-103260
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kutzneria.
REFERENCE   1  (bases 1 to 11609901)
  AUTHORS   Jorgensen,T.S., Gren,T., Kontou,E.E., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Complete Genome Sequence of the Rare Actinobacterium Kutzneria sp.
            Strain CA-103260
  JOURNAL   Microbiol Resour Announc 10 (30), e0049921 (2021)
   PUBMED   34323613
REFERENCE   2  (bases 1 to 11609901)
  AUTHORS   Joergensen,T.S., Gren,T., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2021) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-APR-2021
            Assembly Method :: Flye v. 2.8-b1674; unicycler_polish v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 87.0x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:18:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,326
            Genes (coding)                    :: 10,257
            CDSs (with protein)               :: 10,257
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 9 of 69
            Pseudo Genes (incomplete)         :: 63 of 69
            Pseudo Genes (internal stop)      :: 2 of 69
            Pseudo Genes (multiple problems)  :: 5 of 69
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:59:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1380085
            Orig. end                         :: 1402669
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP073318.1.
            Bacteria and source DNA available from Professor Tilmann Weber,
            Technical University of Denmark, Kemitorvet Building 220, room 327D
            2800 Kgs. Lyngby, Denmark.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22584
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22584
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22584
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12584]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12584
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(799..812)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            990..2270
                     /locus_tag="JJ691_RS06090"
                     /old_locus_tag="JJ691_12170"
     CDS             990..2270
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (13-351). E-value: 3.7e-84.
                     Score: 274.6. Matches aSDomain:
                     nrpspksdomains_JJ691_RS06090_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801880.1"
                     /locus_tag="JJ691_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12170"
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_249227718.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.4e-84, bitscore:
                     281.2, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.8e-05, bitscore:
                     21.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTRSPGLPRAAGGTGAEVFDVDGRRYLDGSGGAVVTSIGHGVTE
                     VVDAIAEQARRIAYAHGTAFASKALDDYADALAPLLPFDDPRIYPVSGGSEAVETALKM
                     ARAYHLARGEDRHVIIGRQGAYHGNSRGALDVSGRAGLRMPYRPWLGAAWHTSAPYEYR
                     CPAPDHPTGCGAWHAGRLDRMITEEVAAFIAEPVAGAALGACVPPDDYWPAVAAVCRQR
                     GVLLIVDEVMTGFGRTGRWFACEHWGIRPDILVTAKGAASGYWPLGLAVCTAEVRDTIG
                     AFVHGFTYSHHPVGAAAGHAVLKVLQDQDLVAAAEQRGRDLAQALRDRLADHPAVGDIR
                     GIGLLQAVELVADPESKKPFARADQVAEKVVAQAKESGLLVYHSTGCADGRDGDLLLFG
                     PPLVITETQVAELADKAAAAIRRVRGR"
     aSDomain        1029..2042
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JJ691_RS06090_Aminotran_3.1"
                     /evalue="3.70E-84"
                     /label="JJ691_RS06090_Aminotran_3.1"
                     /locus_tag="JJ691_RS06090"
                     /protein_end="351"
                     /protein_start="13"
                     /score="274.6"
                     /tool="antismash"
                     /translation="GTGAEVFDVDGRRYLDGSGGAVVTSIGHGVTEVVDAIAEQARRIA
                     YAHGTAFASKALDDYADALAPLLPFDDPRIYPVSGGSEAVETALKMARAYHLARGEDRH
                     VIIGRQGAYHGNSRGALDVSGRAGLRMPYRPWLGAAWHTSAPYEYRCPAPDHPTGCGAW
                     HAGRLDRMITEEVAAFIAEPVAGAALGACVPPDDYWPAVAAVCRQRGVLLIVDEVMTGF
                     GRTGRWFACEHWGIRPDILVTAKGAASGYWPLGLAVCTAEVRDTIGAFVHGFTYSHHPV
                     GAAAGHAVLKVLQDQDLVAAAEQRGRDLAQALRDRLADHPAVGDIRGIGLLQAVELV"
     misc_feature    2288..2302
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.09"
                     /tool="antismash"
     regulatory      2327..2536
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            2642..5014
                     /locus_tag="JJ691_RS06095"
                     /old_locus_tag="JJ691_12180"
     CDS             2642..5014
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018682359.1"
                     /locus_tag="JJ691_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12180"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_249227719.1"
                     /transl_table=11
                     /translation="MTQTVARVDVDPHPTMRVRKRSGAFETVDVNKIVKAVGRCAVGLA
                     EVDPLRVATKTINGLYDGATTEELDRLSIQTAAELVSEEPEYSKLAAQLLAAYIDKEVR
                     LQGIHSFSQSIELGHREGLIGDETAKFVATHARKLDDAIDADGDRRFEYFGLRTVYDRY
                     LLRHPDKRAVVERPQYWLLRVACGLSHTAAEAIRFYRLMSSLAYLPSSPTLFNSGTRHT
                     QMSSCYLLDSPRDELESIYERYAQVAQLSKFAGGIGVQWSRIRSRGALIRGTNGHSNGI
                     VPWLRTLDASVAAVNQGGRRKGAACVYLETWHPDVEEFLELRDNTGEDARRTHNLNIAN
                     WIPDEFMRRVEADADWSLFNPDETPELPDLWGEDFDRAYRAAEQAGRAVRTVKARDLYA
                     KMMRTLAQTGNGWMTFKDTANRTCNQTAEPGNVVHLSNLCTEILEVTSDTETAVCNLGS
                     VNLGAHLAGDSMDWDRLRETVRTAVTFLDRVIDINYYPTAPAGRSNPRWRPVGLGVMGL
                     QDVFFKLRLDFDSATAKELSTRIAEEIYLTALETSADLAASAGAHPAYNQTRAAQGDLQ
                     PDLWGVTPTQTERWAQLRERVAESGLRNSLLIAIAPTATIASIAGCYECIEPQVSNVFK
                     RETLSGEFLQVNTYLVAELKKHGRWTAETRAQLKRDDGSAQALAGLPEASRSLFRTAWE
                     LPQRSLIDLAAARGPYVDQSQSLNLFVASPTIGKLSSMYRYAWQSQLKTTYYLRSRPAT
                     RIQQATVPAAPAVDATESIAAGIACSLENPESCEACQ"
     gene            5011..6039
                     /locus_tag="JJ691_RS06100"
                     /old_locus_tag="JJ691_12190"
     CDS             5011..6039
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018682358.1"
                     /locus_tag="JJ691_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12190"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_249227720.1"
                     /transl_table=11
                     /translation="MTTLENTARKQSLLDPGMDLTLRPMRYPLFYERFRDAIKNTWTVE
                     EVDLHSDLADLKKLTPAEQHLINRLVAFFATGDTIVANNLVLNLYEHVNAPEARLYLSR
                     QLFEEAVHVQFYLTLLDTYLPDENERAEAFAAVENIPSIRDKAEFCFKWIDSIEHLNRL
                     HSKADRRAFLLNLICFAACIEGLFFYGAFAYVYFLRSRGLLNGLASGTNWVFRDESMHM
                     AFAFDVVDTVRREEPDLFDDELHEQVRQMLREAVDAETKFAEDLLGQGVAGMSLADMRS
                     YLEHVADRRLAALGLAPEFNAKNPFAFMELQDVQELSNFFERRVSAYQVAVTGTVSFDE
                     DF"
     gene            6123..6647
                     /locus_tag="JJ691_RS06105"
                     /old_locus_tag="JJ691_12200"
     CDS             6123..6647
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012791.4"
                     /locus_tag="JJ691_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12200"
                     /product="universal stress protein"
                     /protein_id="WP_211767811.1"
                     /transl_table=11
                     /translation="MDGVGRVVVGVDGSVGSLQALRRAVTEARMRSVPLVAVIAWTAPG
                     GEAAYRRTFDVQLKRLWEQGAWERLARAWDEALGGIPDDVDVRQVAVRADAGKALVCVA
                     DDENDLMVIGAGRRSLWRRAFIPLVPRYCAAHARCTVLLVPPSPLSQQMDHGMLPRLLR
                     RRRAVNDLVGH"
     gene            complement(6644..7858)
                     /locus_tag="JJ691_RS06110"
                     /old_locus_tag="JJ691_12210"
     CDS             complement(6644..7858)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="JJ691_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12210"
                     /product="cytochrome P450"
                     /protein_id="WP_211767812.1"
                     /sec_met_domain="p450 (E-value: 8.8e-19, bitscore: 66.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDVLARALDDDIRDDPYPYLAWLRENHPVHQGPAGFYLVATHA
                     DCLAVTANAERFRGPHEHEIPELFPLASRYSAVAMLVDALAMKNPPAHSRLRRLYNRDF
                     TARHVDKMRADTALRCAQILDDVEAPLRDGEAVDAYERITRLLPQAVLADLLGLPESDR
                     GWLFDRFLAVLSTFVPGVTVEMLDAAQKASDEVRDYMVDLIDLRRRTPAEGLLSDWVQV
                     HHNDPDTFSYPELLSMLWGLVAGGVDTTASALSNGVLAMLRHPEHNSWLLDDARAYANE
                     VLRHESPSFVAGIPRFAVADTELSGVLIPAGSDVRTLLGAANRDPAVFPDPDRFDPARD
                     TAKSLSFGRGIHFCLGANVALQELTTLLPALHQRFPALRLADRPRWRRSLPVRAIEKLP
                     VALDI"
     gene            complement(7870..8784)
                     /locus_tag="JJ691_RS06115"
                     /old_locus_tag="JJ691_12220"
     CDS             complement(7870..8784)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013226.4"
                     /locus_tag="JJ691_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12220"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_211767813.1"
                     /transl_table=11
                     /translation="MSTVTTTGFWPAVRRVHRLEYPFPLAYACHGLWGAAYAVATPAGL
                     LNLPVLLAVVAAIIPIIAQNPLNAGQDIRSDSAHPGKHSIAVAARRLGVRRTLWWSGTE
                     FAVAILLAALAGSPLAVSAVTVCVLLHLAYNLEPIRLKRRGFANPLYFGLTFGFLPFLT
                     SFAAARADLPGWAWLVGAGFGGLMAGRTLWWAVPDRDADAAGGDRTLVVWLGARRAWLT
                     ACLLTATGIAVLGWGVWLRLGPAWALVALAATGLFLVIKLRELGRVRDDRLPSERRMRL
                     RTLTVVTLTDTLVTLVPLIASMI"
     gene            complement(8772..10004)
                     /locus_tag="JJ691_RS06120"
                     /old_locus_tag="JJ691_12230"
     CDS             complement(8772..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005452086.1"
                     /locus_tag="JJ691_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12230"
                     /product="cytochrome P450"
                     /protein_id="WP_211767814.1"
                     /sec_met_domain="p450 (E-value: 9.6e-45, bitscore: 152.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTANQRRFAFRTLSFLDSLDEQHGVVTLTPRRLLVSSPEAVGRIF
                     RADRRACLEGTSTLGPLVGPRSLLFANGARHTAYRKTIGPALRGDRLRGVVLDTARAEI
                     DRLTPGSVITLPAWTRSVTLKVIGRVVLGDADPVFLRSFTEWVEGALGSRRRTLLYRHA
                     RLHPAVPSPWRTFLRQRETIDRELLAHVRTRASDGSIAGLLLSGGTPLGVLDDDELRDQ
                     LVSLLFAGHETTASALAWTLYWLHQNENVRRDLLDELAASDEAGETPLLDAVCHESLRL
                     SPPAMIAGNRVFDDASDLVGRELPAGSRLTPCIYLAHRRRDAYSDPHRFDPQRFLGRRP
                     SSQQYFPFGGGVRRCLGADLAMTELRMITAAVLSGLSLRCVNPELGVPHLRGPAMGPGP
                     GLRMEVLACRR"
     gene            complement(10001..11389)
                     /locus_tag="JJ691_RS06125"
                     /old_locus_tag="JJ691_12240"
     CDS             complement(10001..11389)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="JJ691_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12240"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_211767815.1"
                     /sec_met_domain="T2TS (E-value: 1.3e-86, bitscore: 290.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADPYGQTTPSIYETARMVSLAPWLGGHADRVRFLLAEQQPNGAW
                     GQPDGYGVVPTLSATEALLRSPETRDAAMRGLHVLFDWNDRAIPDTIAAEVLVPQLVED
                     INRHLDEAGWPRRLGLPAGIDSSLLTALRARAAAGTPPPAKLWHSLEFLGPAAVAAAGV
                     APEHGLVCGSAAATAAWLGDGPAPANLEAMQARHGGPVPGICPITVFENAWIAAAMADA
                     GLAHLVSPQIIDELRAACGPDGAPAAPGLPADADDTAAVLYALAKLGSPVSSECLWRYE
                     TTDYFQCFLGERSPSTSTNAHVLDALIADPTRGARHEAAIAKVARWLVALQEPDGSWWD
                     KWHASPYYATQCCVAALARSGQPGATEAVERAGRWVLATQRADGSWGRWRGTDEETSYA
                     VQILLHTNGSPGAVARGCEFLRREDRDGQPDPLWHDKDLYAPVNVIAANRRATLHLATL
                     AHAR"
     gene            11604..12584
                     /locus_tag="JJ691_RS06130"
                     /old_locus_tag="JJ691_12250"
     CDS             11604..12584
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="JJ691_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12250"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_211767816.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.5e-47, bitscore:
                     159.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTQPLLALAAIDRELFQSTMTTAGRCPEPGLDAGLRPLLARPGK
                     RLRPALVFAMAACGSEPDRIAAAKCAAALELTHLSSLIHDDLIDRAESRGDLPTLHTSA
                     GLAAAVVGGDYLIAVAGRLVTEVSAEAALIWHQAYADLCVGQARELANSHRTDVTTVDY
                     LAAIRGKTAALMAASCRLGALCGGLGPAEVEAAARFGEAFGMVFQLVDDLMDVVATADS
                     WGKPVGQDVPNGVYTAAVIAALEHADERFQRLFGPSMTPAQVDLVLDRARRIGTGPVLD
                     LIDGYVREAGRELAALPAAPALADLPNTYVTKTLGRAVIVTERVS"
     gene            12581..13906
                     /locus_tag="JJ691_RS06135"
                     /old_locus_tag="JJ691_12260"
     CDS             12581..13906
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="JJ691_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12260"
                     /product="cytochrome P450"
                     /protein_id="WP_211767817.1"
                     /sec_met_domain="p450 (E-value: 3.4e-77, bitscore: 259.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPNSMPGAVPLLGHLPALARRPLEFLRAAQAQRDVVLLRLGVEK
                     VYFVNQPEQLRTLLVTDPGRFDKGVQFEKAAAVIGNSLPVSAGAFHRRQRKMIRPAFLQ
                     ARLREYFDVMRDCAETAVGQWSADTDITAALRDVVGAITARTLFSPDFPDDERRELTGL
                     IDALDKGVALRVLDPTGLAGRLPLPVNRRFEQARARTHELMEAFIARYRERGDDRHDLM
                     STLLAARDDGQLMPDRQIRDEAIAILQAGFETTARALCWACHALGEHPEMQRRVGDEVS
                     EGPLGYDDLPRLDLTRRVVTEALRLYPPLYLMTRRAIEDVQIGGHTIPSGSTVLFSPYA
                     LHHDPAIYPDPERFDPDRWLPDARPEIQGVTYLPFGAGLRNCLGEQFAMMELVVVLSAL
                     MRRWSLERIPTVAVRPKLSFVLAPSATGVRLSLPAASGISAC"
     gene            complement(13869..14162)
                     /locus_tag="JJ691_RS06140"
                     /old_locus_tag="JJ691_12270"
     CDS             complement(13869..14162)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643630.1"
                     /locus_tag="JJ691_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12270"
                     /product="MGMT family protein"
                     /protein_id="WP_211767818.1"
                     /transl_table=11
                     /translation="MDEALHERMREAIKDVPPGRVSTYGDIAAMVGAPSPRMVGAMLSE
                     DGHDLPWHRILRANGTPAPQIAHEQLARLRAEGVLADGQRINMRKYRWQPED"
     misc_feature    complement(14146..14160)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.71"
                     /tool="antismash"
     gene            complement(14206..16464)
                     /locus_tag="JJ691_RS06145"
                     /old_locus_tag="JJ691_12280"
     CDS             complement(14206..16464)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021021.4"
                     /locus_tag="JJ691_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12280"
                     /product="M64 family metallopeptidase"
                     /protein_id="WP_249227721.1"
                     /transl_table=11
                     /translation="MLRRILIAGVASALALLPLPVAAQADTPTGTVVPIRVTGDPAQRF
                     NLVILGDGYTAADMPKFRADVDKHMNVLFTFEPFKSYRNYMNVYTVEIPSSVSGVSCDP
                     DITSPQRNTPLHMEFWSGCDPQGVQRGLYMDENAATAYANLVPGTTAANRQILGIANST
                     TYGGIGGTYATASGGNAMSSLITPHELGHSLGGLQDEYDYYARGVRGDAYTGGEPDSVH
                     HTLLTEQQMAQQQKKWWRWLGEPSEAGGTIGRYESGMYSSSGVWRPSAHSIMKTLGYYY
                     DQVGREDMVKSISAKTSIVQDTTPTAQPIGADRVVFAEPMHPNSHQLTIAWSLDGQALS
                     ANGQQLDLRTLNLKAGKHKLTATVTDPTDFVRDPVIKQALTNTHTWTVDTAVKTPPTTT
                     AVDFADTTETDRPIGADEVVFADTTHPTNQVVPVRWALDGNPLATTANDVDLKNLKLTG
                     SHTLTATVGGKSRSWTVDATDPSTSYQLSNALLSVKKADGTSEYVYNGPFDMRLTAADD
                     RTGSLVSEFRTDGDGWFNYFGWPTDSTQPWHFTPSGTEIDHLVYGKLGKPRLSPWDDAT
                     PSYGQHTIEYRTTDAAGNTGAAKSFQVNLLPAPPACTKTITGQHSGALVVTDGVTCLDH
                     ASVTGAIVVSPGASLVATGSTITGGVSASNANAVELLDTTVHGAASITGVTQDVTIVGG
                     RVDGALVLSGNHTGARQPVVAGVAVTGALSCAGNAPAPSNIAAPNTVRGGAIGQCSGL"
     misc_feature    complement(16408..16410)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16542..18275
                     /locus_tag="JJ691_RS06150"
                     /old_locus_tag="JJ691_12290"
     CDS             16542..18275
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155503.1"
                     /locus_tag="JJ691_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12290"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_211767819.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 5.5e-49, bitscore:
                     165.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTAEMIVDSWIPMTTAVSPDGRWVAYTQRQVGRPVSEVWLAGGD
                     HPPRRLAVGTDPRWDPDSLSLCYLVDGVELHRITLSGTDIVLVNWPAGIDSHLPLVDGV
                     AFVAADSPAPEIEVRSVVRPSRLRLADSSGIRVLYGDRHVAEVAQQPGGGPLAVLTWSS
                     HEVDPGLLSPSLHVVSLSGEVRDLGPAVVGAHSPVWRLVGDWRVAYLAHTPPSLQSGTA
                     VYDVVDGNLTAGLPACPVELVQMADGDPLVVVASGLDTFVRRLSGPVVSRHTGLVEAVS
                     AGGESVAAIVSTADDPPDVHFRGVRVTDLRPWTRDIEWGTQRRFSYQASDGLELEGLLI
                     LPPVGTGPFPLVTIVHGGPYDRFADQFGLHWVPSGQWLALAGYAVFLPNPRGSQGRGHE
                     FATTVTGAVGQEEWTDILTGIDLLVADGVADAARLGIYGWSHGGFMAAWAIGHSNRFAA
                     AIMGAGVTDWGMLVGSGEWGMFEASLGGSTGWEGVGPHRHDELSPISYAANVRTPVLIV
                     HGAADTNVPVAQSEYFHRALRYYGVEHEFVVYPREGHSFREREHQVDLHHRVREWFGRW
                     L"
     misc_feature    16731..16733
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18568..19371)
                     /locus_tag="JJ691_RS06155"
                     /old_locus_tag="JJ691_12310"
     CDS             complement(18568..19371)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014741.4"
                     /locus_tag="JJ691_RS06155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12310"
                     /product="DUF222 domain-containing protein"
                     /protein_id="WP_256449372.1"
                     /transl_table=11
                     /translation="MWSVNRPCGLGGDSTPDDVTPGQRTGHPSPRQFTTPTSTDRLSER
                     HCLKAREDRRVEFTPLPDGMAKLSIILPAIDARQAYDILTCDARSLPKDDRTTDQKRAD
                     AFLDRFLGYGVDRKVKVHVTISLETLMGLTEDPGLLDGYGPIAADSARELAMHGPWRGL
                     LLDEYRRASELSRDQYRPTADIKQFAELNAGGVCSAPGCTTPIQELDHTTPWPQGKTNA
                     TQLKGYCAHHHHLKHGDYTATLDEDGTLHWRTPLGRHYTTHPHQY"
     misc_feature    complement(19246..19248)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19313..20563
                     /locus_tag="JJ691_RS06160"
                     /old_locus_tag="JJ691_12320"
     CDS             19313..20563
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612226.1"
                     /locus_tag="JJ691_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12320"
                     /product="IS4 family transposase"
                     /protein_id="WP_211764286.1"
                     /transl_table=11
                     /translation="MTSSGVESPPRPQGRLTDHIGLGVLSARFDRDLIEEVLNRTGRRE
                     RRSRRLPAHVMIRYVIAMGLFFAESYDEVMRRLVGNLRKLGSWVDDWQVPTKSAITQAR
                     QRLGPHPVKALFERACVPLATSATKGAWLARRRVMAIDATSFDVADTPDNAERFGRTGS
                     GPKASAYPKLHVAALAECGSHAIVGAVLGSVRTGERTLAADLAAWVGPEMLVLADAGLY
                     SYELFGRFAATGADLAWRIGASVSVGLVRWLPDGSYLALIYRSGLGAERRARLVAQAHA
                     GQDIQADLARLVRVVEYTVPDRNPDGELIVVITTVLDPHELPALELAEAYHQRWEAESA
                     LDELKTDLRGRGEVLRSKTPDLVEQQMWGLLLAHYAIRGLLLDAADPAGYDPDRMSFIK
                     GLRVVRRQVTDQAAITP"
     gene            complement(20759..21262)
                     /locus_tag="JJ691_RS06165"
                     /old_locus_tag="JJ691_12330"
     CDS             complement(20759..21262)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014741.4"
                     /locus_tag="JJ691_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12330"
                     /product="DUF222 domain-containing protein"
                     /protein_id="WP_211767821.1"
                     /transl_table=11
                     /translation="MKELTQELESMEPSGAIVDLLLGANVATLTEEQKLTALVLVHRAI
                     ASLHHVRLSLLHEVEDTAEIAMAIHEPEQSMVHQKHRSAMLDRLPRMAELLRRGEIDLR
                     RMETVDDRVVHLAKPELVTQVENALVDLAPSLTRTQLARRTTKAVAEADPLGYDQRRLK
                     AQCR"
     misc_feature    complement(21631..21642)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.69"
                     /tool="antismash"
ORIGIN
        1 ctgcccatct actcccggat gtgccaggcg ctggccgaga cggcaccgat cgacgggccg
       61 gtgcgggtgt tcctgagcaa ctccggcgcg gaggcggtcg agggcgcgct gaagctggcc
      121 cggtactgca ccggccgccc gtacgtgatc agcttctacg gcgcgttcca cggccgcagc
      181 tacggcgcgg tcagcctgac ggcatcgaag gccaagtacc acaagggttt cggcccgctg
      241 ctgcccggtg tgctgcacgc cccgtacggc agcgacgaga cgttcgagca cctggagaac
      301 ctgctgttcc ggcaccaggt gtcgccggac gaggtggcgg cggtcttcgt cgagccgatc
      361 cagggcgagg gcggctacat cgtgccgccg gacggctggc tgcgcaggct gcgggaactg
      421 tgcgaccggc acgggatcct gctgatcgcc gacgaggtgc agtcgggcat gggccgcacc
      481 ggaaagctgt gggcgatcga gcacaccggc gtgcggccgg atgtcctgat cagcgccaag
      541 ggtattgcct cggggctgcc gctcggcgcg ttcatcgccc gtgccgacct gatggagaag
      601 tggtccgccg gcgcgcacgg ctccacctac ggcggcagcc cggtgccgtg tgcggccggg
      661 ctggccacgc tggcggtcat cgaggaggaa ggcctgctgg ccaacgcttc cgtggtcggc
      721 gaccagctgc tggccgggct tcgcgagctc cagcaacgct tcccggagtc gatcaccgac
      781 gtccgcggcg tcggcctgat gatcggcgtc gagttcgcca ccgccgagct ggccgcccag
      841 gtgcagcagc gggcgttcga gctcgggctg ctggtgctgg agtgcggtga gagcagcatc
      901 cggatgtcgc cgccgctggt cgtcacggcc gaggaggctc ggaccgcgct ggagctgttc
      961 ggccgggccg tcgccggatg agtcggcacg tgttcacccg ttcccctggt ctgccgcgcg
     1021 cggccggggg aacgggggcc gaagtgttcg atgtggacgg tcgccggtac ctggacgggt
     1081 ccggcggcgc ggtggtcacg tccatcggtc acggcgtcac cgaggtcgtc gacgccatcg
     1141 ccgagcaggc ccggcggatc gcctacgcac acggaaccgc cttcgcctcc aaggcattgg
     1201 acgactacgc cgacgcgctg gccccgctgc tgccgttcga cgacccgcgg atctacccgg
     1261 tgtccggcgg cagcgaggcg gtggagacgg cgctgaagat ggcccgggcc tatcacctgg
     1321 cccgcggcga ggaccggcac gtgatcatcg gccggcaggg ggcctaccac ggcaattccc
     1381 gtggtgcgct ggatgtttcc ggccgggccg ggctgcgcat gccgtaccgg ccctggctcg
     1441 gcgcagcctg gcacacctcc gcgccgtacg agtaccgctg cccggccccg gaccatccga
     1501 ccgggtgcgg cgcctggcac gcgggccgac tggaccggat gatcaccgag gaggtcgccg
     1561 cgttcatcgc cgaaccagta gccggggcag cgctcggcgc gtgcgtgccg ccggacgact
     1621 actggccggc ggtcgccgcg gtctgccggc agcggggcgt gctgctgatc gtcgacgagg
     1681 tgatgaccgg cttcggccgc accggccgct ggttcgcctg cgagcactgg ggaatccggc
     1741 ccgacatcct cgtcacggcc aagggtgcgg cctcgggcta ctggccgctc gggctggcgg
     1801 tttgcaccgc cgaggtccgg gacaccatcg gggccttcgt gcacggcttc acgtactcgc
     1861 accacccggt gggcgcggcg gccgggcacg cggtgctgaa ggtgttgcag gaccaggact
     1921 tggtggccgc cgctgagcaa cgcggccggg atctggccca ggcgctgcgc gaccggctgg
     1981 ccgatcaccc ggcggtcggc gacatccggg gcatcggctt gctccaggcg gtcgagctgg
     2041 tggccgaccc ggagtcgaag aagccgttcg cccgggccga ccaggtcgcc gaaaaggtcg
     2101 tcgcccaggc gaaggagagt ggcctgctgg tctaccactc gaccggctgc gccgacggcc
     2161 gcgacggcga cctgctgctg ttcggcccgc cgctggtgat caccgagacc caggtggccg
     2221 aactggcgga caaggccgcc gccgcgatcc gccgggtccg cggtcgctga cgaccttcga
     2281 cacgccgaca caatatgtgg gtgcttgcga ctgatcccca cccatgtatt gtgttcaccg
     2341 agctggttcg gccgccccgc cagggtggtc gtcgtaagag ggaacccggt gcgagtccgg
     2401 gactgccccg cagcggtgaa cgggaacgac cgccgtcacg aagcactgga cgcgacgcgt
     2461 ccgggaagcg acggccagta ggtgcctgcc ggcatgcccg tgagtccgaa gacctgcccg
     2521 ctcgcccgtt cgcaccgtga acgggctcgt gtccaggccc cgagggaggg cgtggggatc
     2581 gccggcacgg cgggtcctcg cgcgtgcccg aaaggccgac agcgtgcgag gagctcaggc
     2641 tgtgacgcag acagtcgcgc gggtagacgt cgatccccac ccgacgatgc gggtcagaaa
     2701 acgaagcggc gccttcgaga ccgtcgacgt gaacaagatc gtcaaggcgg tcggccgctg
     2761 cgcggtcggg ctggccgagg tggacccgct gcgggtggcc accaagacga tcaacggcct
     2821 gtacgacggc gcgaccaccg aggagctgga ccggctgtcc atccagacgg cggccgagct
     2881 ggtctccgag gagcccgagt actccaagct ggcggcccag ctgctggccg cgtacatcga
     2941 caaagaagtt cgcctgcaag gcatccactc gttcagccag agcatcgagc tgggccatcg
     3001 cgagggtctg atcggcgacg agacggccaa gttcgtggcc acccacgccc gcaagctgga
     3061 cgacgccatc gacgcggacg gcgaccgccg gttcgagtac ttcggcctgc gcacggtgta
     3121 cgaccgctac ctgctgcgcc accccgacaa gcgcgcggtg gtggagcgcc cgcagtactg
     3181 gctgctgcgc gtggcctgcg gcctgtcgca cacggccgcc gaggcgattc gcttctaccg
     3241 cctgatgtcc tcgctggcgt acctgccgag ctcgccgacg ctgttcaact cgggcacccg
     3301 gcacacccag atgtcctcct gctacctgct ggactcgccg cgcgacgaac tcgagtcgat
     3361 ctacgagcga tacgcgcagg tggcgcagct gtccaagttc gccggcggca tcggcgtgca
     3421 gtggtcccgg atccgttccc gtggcgcgct gatccgcggc accaacggcc actccaacgg
     3481 catcgtgccg tggctgcgca cgctggacgc ctcggtggcg gcggtcaacc agggcggccg
     3541 gcgcaagggc gcggcctgcg tgtacctgga gacgtggcac ccggacgtcg aggagttcct
     3601 ggagctgcgc gacaacaccg gcgaggacgc gcgccgcacg cacaacctga acatcgccaa
     3661 ctggatcccg gacgagttca tgcgccgggt cgaggccgac gccgactggt cgctgttcaa
     3721 cccggacgag acgccggagc tgccggacct gtggggcgag gacttcgacc gcgcctaccg
     3781 cgccgctgag caggccggcc gcgcggtgcg cacggtgaag gcccgtgacc tgtacgccaa
     3841 gatgatgcgc acgctggccc agaccggcaa cggctggatg accttcaagg acaccgccaa
     3901 ccgcacctgc aaccagaccg ccgagcccgg caacgtggtg cacctgtcca atctctgcac
     3961 ggagatcctg gaagtcacca gcgacactga gaccgcggtc tgcaacctcg gctcggtcaa
     4021 cctgggcgcg cacctggccg gcgattccat ggactgggat cggctgcggg agaccgtccg
     4081 caccgcggtc acgttcctcg accgcgtgat cgacatcaac tactacccga ccgcgccggc
     4141 cggccggtcc aacccgcgct ggcgcccggt gggcctgggc gtgatgggcc tgcaggacgt
     4201 gttcttcaag ctgcgcctgg acttcgactc ggccacggcc aaggagctgt ccacccggat
     4261 cgccgaggag atctacctca cggcgctgga gacgtcggcc gacctggccg cgtcggcggg
     4321 cgcgcacccg gcgtacaacc agacccgggc ggcccagggc gacctgcagc cggacctgtg
     4381 gggcgtgacg ccgacgcaga ccgagcgctg ggcccagctg cgggagcgtg tcgccgagag
     4441 tggcctgcgt aactcgctgc tgatcgccat cgcgccgacg gcgaccatcg cctccatcgc
     4501 cggctgctac gagtgcatcg agccgcaggt ctccaacgtg ttcaagcggg aaaccctgtc
     4561 cggggagttc ttgcaggtca acacctatct cgtcgcggag ctgaagaagc acggccggtg
     4621 gaccgcggag accagggccc agctcaagcg ggacgacggc tccgcgcagg cgctggccgg
     4681 cctgcccgag gccagccgct cgctgttccg caccgcgtgg gagctgccgc agcggtccct
     4741 gatcgacctg gccgccgcgc gtggcccgta cgtcgaccag agccagtcgc tgaacctgtt
     4801 cgtggcctcg ccgacgatcg gcaagctgtc gtcgatgtac cgctacgcct ggcagtccca
     4861 gctgaagacc acgtactacc tgcggtcccg cccggcgacc cgcatccagc aggccaccgt
     4921 gccggcggct cccgccgtcg acgccacaga gtcgatcgct gctggcatcg cctgctccct
     4981 tgagaacccc gaatcgtgtg aggcctgcca gtgaccacgc tagagaacac cgcccgcaag
     5041 cagtctttgc tcgacccggg catggacctc acgctgcgcc cgatgcgcta tccgctgttc
     5101 tacgagcgtt tccgtgacgc catcaagaac acgtggacgg tggaggaggt cgacctgcac
     5161 tccgacctcg ccgacctgaa gaagctgacg ccggccgagc agcacctgat caaccgcctg
     5221 gtcgcgttct tcgccaccgg cgacacgatc gtcgccaaca acctggtgct caacctgtac
     5281 gagcacgtca acgcgcccga ggcgcggctg tacctgtcgc ggcagctgtt cgaggaggcc
     5341 gtgcacgtcc agttctacct gacgctgctg gacacctacc tgcccgacga gaacgagcgg
     5401 gccgaggcgt tcgcggcggt ggagaacatc ccgtccatcc gggacaaggc cgagttctgc
     5461 ttcaagtgga tcgactccat cgagcacctg aaccgcttgc acagcaaggc cgaccggcgg
     5521 gcgttcctgc tcaacctgat ctgcttcgcc gcctgcatcg agggcctgtt cttctacggt
     5581 gcgttcgcgt acgtgtactt cctgcgttcg cgcggcctgc tcaacggcct ggcctcgggc
     5641 accaactggg tgttccgcga cgagtccatg cacatggcgt tcgccttcga cgtggtggac
     5701 accgtgcgcc gcgaggagcc cgacctgttc gacgacgagc tgcacgagca ggtccggcag
     5761 atgctgcgcg aggcggtgga cgcggagacc aagttcgccg aggacctgct cggccagggc
     5821 gtggccggaa tgtcgttggc ggacatgcgt tcctacctgg agcacgtggc cgaccgccgg
     5881 ctggccgcgc tgggcctggc tccggagttc aacgccaaga acccgttcgc cttcatggag
     5941 ttgcaggacg tgcaggagct gtccaacttc ttcgagcgcc gggtgtccgc atatcaggtc
     6001 gcggtgaccg gaaccgtgag cttcgacgag gacttctgat ctgtgccgct gggcacacat
     6061 ctcatcaaga actcgttcgg gtgacgtaac cacttgcgcc ggagacctac catgttccgg
     6121 tgatggatgg tgttggacgg gtcgtcgtcg gtgtcgacgg ctcggtcggc agcttgcagg
     6181 cgttgcggcg ggcggtgacc gaggcgcgga tgcgctcggt gccgctcgtc gcggtgatcg
     6241 cgtggacggc gccgggcggc gaggccgcct accggcgcac gttcgacgtg cagctcaagc
     6301 ggttgtggga gcagggcgcc tgggagcggc tggccagagc gtgggacgag gcactgggcg
     6361 gcatccctga cgatgtggac gtgcggcagg tggcggtgcg ggccgacgcg ggcaaggcgt
     6421 tggtctgtgt cgcggacgac gagaacgacc tgatggtgat cggcgcgggc cggcgcagct
     6481 tgtggcgccg ggccttcatt cccctggtgc cgaggtactg cgcggcccac gcgcggtgca
     6541 cggtgctgct ggtgccgccg tcgccgttga gtcagcagat ggatcacggc atgctgccgc
     6601 ggctgctgcg ccgcaggcga gccgtgaacg atctcgtcgg tcactagata tcgagggcca
     6661 ccgggagttt ctcgatggcc cgtaccggca acgaacggcg ccaccgcggc cggtcggcca
     6721 gtcgcagcgc gggaaaccgc tggtgcagcg ccggcagcag ggtcgtcagc tcctggagag
     6781 cgacgttggc gccgaggcag aagtggatgc cgcgaccgaa gctgagcgac ttcgcggtgt
     6841 ccctcgcggg atcgaaccga tcgggatccg ggaacacggc cggatcccgg ttggccgcgc
     6901 cgagcagcgt ccgcacgtcg gagccggccg ggatgagcac gccgctgagt tcggtgtccg
     6961 cgacggcgaa acgcggaatg ccggcgacga atgacggcga ctcgtggcgc agcacctcgt
     7021 tggcgtaggc gcgggcgtcg tccagcagcc acgagttgtg ctcggggtgt cgcagcatgg
     7081 ccagcacgcc gttgctcagg gcggacgccg tggtgtccac gccgccggcg accaggcccc
     7141 acaacatgct cagcaactcg ggatagctga aggtgtccgg gtcgttgtgg tgcacctgca
     7201 cccagtccga cagcagcccc tcggccggtg tccgccgccg caggtcgatc aggtcgacca
     7261 tgtagtcccg gacctcgtcg ctggctttct gggcggcgtc aagcatttcc acggtcacgc
     7321 cgggcacgaa ggtggacagc acggcgagga agcggtcgaa cagccagccc cggtcggact
     7381 cgggcaggcc gagcagatcg gcgagaaccg cctgcggcag caggcgagtg atccgctcgt
     7441 aggcgtccac ggcttcgccg tcacgcagcg gggcctcgac gtcgtcgagg atctgtgcac
     7501 agcgcagggc ggtgtcggcc cgcatcttgt cgacgtgccg ggcggtgaag tcgcggttgt
     7561 agagccggcg cagccgggag tgcgcgggcg ggttcttcat ggccagcgcg tccacgagca
     7621 tggctacggc gctgtagcgg ctggccagcg ggaacagctc ggggatctcg tgctcgtgcg
     7681 gcccccggaa ccgctccgcg ttcgcggtga cggccaggca gtccgcgtgc gtggccacca
     7741 ggtagaagcc agcagggccc tggtgcacgg gatggttctc gcgcagccag gccagatacg
     7801 ggtaggggtc gtcgcggatg tcgtcgtcca gcgcccgggc cagcacgtcc agtgtcatga
     7861 ggcctttcct cagatcatgc tcgcgatgag cgggaccagt gtcaccagcg tgtcggtcag
     7921 ggtgaccacg gtcagcgtgc gcaggcgcat ccgccgctcg ctgggcagcc ggtcgtcgcg
     7981 gacccgaccc agctcccgca gcttgatcac caggaacaac ccggtggcgg cgagcgctac
     8041 cagagcccac gccgggccga gccgcagcca cacaccccag ccgaggacgg cgatcccggt
     8101 cgcggtgagc aggcaggcgg tcagccaggc ccggcgtgcg cccagccaca ccaccagggt
     8161 ccggtcgccg ccggccgcgt cggcgtcgcg gtcgggcacg gcccaccaca gcgtgcggcc
     8221 ggccatcagc ccgccgaaac ccgcgcccac caaccaggcc cagcccggca gatccgctcg
     8281 ggcagcggcg aaactggtca ggaacggcag gaagccgaag gtcagtccaa agtagagtgg
     8341 attggcgaag ccccgccgct tcaaccggat cggctccagg ttgtacgcca gatgcagcag
     8401 cacacagacc gtcaccgccg acaccgccag cggactaccc gccagggcag cgaggaggat
     8461 ggcgacggcg aactcggtgc cggaccacca cagcgtccgt cgcacgccca gccgtcgcgc
     8521 cgccaccgcg atgctgtgct tgccggggtg ggcggagtcg gaccggatgt cctgaccggc
     8581 gttgagcggg ttctgggcaa tgatcgggat gatcgccgcc accaccgcga gcaacaccgg
     8641 taggttgagc agcccggcag gcgtggcgac ggcgtaggcc gcgccccaga gtccgtggca
     8701 ggcataggcc agcgggaatg ggtattcgag ccgatgaact cgccgtacag ctggccagaa
     8761 tccggtggtg gtcaccgtcg acacgcgagc acctccatgc gcaggccggg gccggggccc
     8821 atcgccggcc cccgcagatg cggcacgccc agctccgggt tcacgcaacg aagggacagc
     8881 ccgcttagca ccgcggcggt gatcatgcgc agttcggtca tggcgagatc ggcgccgagg
     8941 cagcgccgca ctccgccacc gaagggaaag tactgctggc tggacggccg ccggccgaga
     9001 aaccgttgcg ggtcaaagcg atgcgggtcg gaataggcgt cgcggcggcg gtgggcgaga
     9061 tagatgcacg gcgtcaggcg cgacccggcc ggcagttccc ggccgaccag gtcggaggcg
     9121 tcatcgaaca cccggttgcc ggcgatcatc gccggcgggc tgagccgcag cgactcgtgg
     9181 cacaccgcgt ccagcagcgg cgtctccccg gcctcgtcgc tggcggccag ctcgtccagc
     9241 agatcccggc gcacgttctc gttctggtgc agccagtaca acgtccaggc cagcgccgat
     9301 gcggtcgtct cgtggccggc gaacaacagc gacacgagct gatcgcggag ctcgtcatcg
     9361 tccaggacgc cgagtggagt tccgccggac agcagcaggc cggcgatgct gccgtcgctg
     9421 gcccgagtgc gaacgtgggc gagcagctcc cggtcgatgg tttcccgctg gcgcaggaaa
     9481 gtccgccacg gcgacggcac cgccgggtgc aaccgggcgt gccggtagag gagcgtgcgc
     9541 cgccgtgagc cgagggcacc ctccacccac tcggtgaagg agcggagaaa caccgggtcg
     9601 gcgtcgccga gcaccacccg gccgatgacc ttcagtgtca ccgatctcgt ccacgccggc
     9661 agggtgatca ccgatcccgg ggtgagccgg tcgatctcgg cccgggccgt gtccagcacc
     9721 accccgcgca gtcggtcgcc gcgcagggcc gggccgatcg tcttgcggta ggcggtgtgg
     9781 cgtgcgccgt tggcgaacag cagcgagcgg ggccccacca gcgggcccag ggtgctggtg
     9841 ccttccaagc aggcccgccg gtcggcgcga aagattcggc cgacagcttc cgggctcgac
     9901 accagcagcc gacgtggggt cagtgtgacg acgccgtgct gctcgtccag ggagtccagg
     9961 aaggacaggg tccggaaggc gaatcgccgc tggttggcgg tcatcgggcg tgggccaagg
    10021 ttgcgaggtg aagcgtggcc cgccgattcg ccgcgatgac gttcaccggg gcgtacaggt
    10081 ccttgtcgtg ccacagcgga tcgggttggc cgtcgcggtc ctcgcgccgt aggaattcgc
    10141 agccgcgggc caccgctcca ggggatccgt tggtgtgcaa caggatttgc acagcgtagc
    10201 tggtctcctc gtcggtgccg cgccaccggc cccacgaacc gtccgcgcgc tgggtcgcca
    10261 gcacccatcg accggcgcgt tcgacggcct ccgtggcgcc cggctggccg gaccgggcca
    10321 gcgccgcgac acagcactgc gtggcgtagt acggcgacgc atgccacttg tcccaccagc
    10381 tgccgtccgg ttcctgaagg gcgaccaacc accgagccac cttggcaatc gcggcctcgt
    10441 gtcgcgctcc ccgcgtcgga tccgcgatca gcgcatccag aacgtgggcg ttggtgctgg
    10501 tcgacggcga gcgctcgccg aggaagcact ggaagtagtc ggtggtttcg taccgccaca
    10561 ggcactcgct cgacaccggg ctgcccagct tggccagggc atagagcacc gccgccgtgt
    10621 cgtcggcgtc ggccggcaga cccggcgcgg ccggtgcgcc gtccggaccg caggccgcgc
    10681 gcagctcgtc gatgatctgt ggggacacga gatgggccag gccggcgtcg gccatggccg
    10741 cggcgatcca ggcgttctcg aagaccgtga tggggcagat gcccggcacc gggccgccgt
    10801 gacgggcctg catggcctcc aggttggccg gggccggacc gtcgccgagc caggccgcgg
    10861 tggcggcggc ggaaccgcag accaggccgt gctcgggagc cacgccggca gcggcgacgg
    10921 cggccgggcc gaggaattcc aaggagtgcc agagcttcgc cggcggggga gtgcccgcgg
    10981 ccgcccgcgc gcggagcgcg gtgagcagcg aggagtcgat cccggccggc aacccgagcc
    11041 ggcgcggcca gccggcctcg tccaggtgcc ggttgatgtc ctcgaccagt tgcggcacaa
    11101 ggacttccgc ggcgatggtg tcggggatgg cgcggtcgtt ccagtcgaac agcacgtgca
    11161 gcccgcgcat cgccgcgtcc cgggtctccg ggctccgcag cagcgcctcg gtggcgctca
    11221 gcgtcggcac cacgccgtat ccgtcgggct ggccccaggc cccgttcggc tgttgctcgg
    11281 ccagtaggaa ccgcacgcgg tcggcgtggc cgcccagcca gggtgcgaga ctgaccattc
    11341 gggccgtttc gtagatcgac ggagtggtct ggccataggg gtcggccacc aagtcctccc
    11401 agcaaatgat tggtgcccag taaaagattg acgcgttatc cccatcggcc ggagcgtatg
    11461 ggtgaaagcg cggacaccac catcatttgt ggccgaacgg ctactgtgcg gctgagccga
    11521 tcggaccgtt cggccaagcg ctattgccag cctgccgggg ccgggcacga tggcgacaac
    11581 ggcccctcgg aacggtggat cgcatgctga cccaacccct tctcgccctg gcggcaattg
    11641 atcgggagct gttccagtcg acgatgacga cggccggccg atgccccgaa ccgggtctcg
    11701 acgccgggct gcgcccgctg ctggcccggc ccggcaaacg ccttcgtccg gcgctggtgt
    11761 tcgcgatggc ggcctgcggt tccgagcctg atcggatcgc cgccgcgaaa tgcgccgccg
    11821 cgctggagtt gacgcacctc agctcgctga tccacgacga cctgatcgac cgggccgagt
    11881 cccgtggcga cctgcccacg ctgcacacca gcgccgggct ggccgccgcg gtggtcggcg
    11941 gcgactacct gatcgccgtg gccggtcggc tggtcaccga ggtgtcggcc gaggccgcgc
    12001 tgatctggca ccaggcctac gccgacctct gcgtcggcca ggcccgcgaa ctggccaaca
    12061 gccaccggac cgacgtcacg accgtcgact acctggccgc cattcgcggt aagacggcag
    12121 cgctgatggc cgcctcctgc cggctcggcg ccctgtgcgg cggcctcggg ccggccgagg
    12181 tcgaggccgc cgcccgtttc ggcgaggcct tcggcatggt gttccagctg gtcgacgacc
    12241 tgatggacgt ggtcgccacg gccgactcgt ggggcaagcc ggtgggccag gacgtgccca
    12301 acggggtgta cacggcggcg gtgatcgccg cgctggaaca cgccgacgag cggttccagc
    12361 ggctgttcgg gccgtcgatg actccggcgc aggtcgacct cgtcctggac cgggcccgcc
    12421 ggattggcac cgggccggtg ctcgacctga tcgacggcta cgtccgcgag gccggccgcg
    12481 agttggcggc gctgccggct gccccggcac tggccgacct cccgaacacc tatgtcacaa
    12541 agacccttgg ccgcgctgtg atcgtcacgg aacgggtgtc atgaaaccga actcgatgcc
    12601 gggtgccgtg ccattgctcg ggcacctgcc ggcgctggcc cgccgtccgc tggaattcct
    12661 tcgtgcggcc caggcgcagc gcgacgtcgt tctgctccga ctgggcgtcg aaaaggtcta
    12721 tttcgtcaac cagccggagc agctgcgcac actattggtc accgatcccg gccgattcga
    12781 caagggcgtg cagttcgaga aggccgccgc ggtgatcgga aacagcctgc cggtctcggc
    12841 cggcgcgttc caccggcgcc agcggaaaat gatcaggccg gcattcctgc aagcccggct
    12901 gcgcgagtac ttcgacgtga tgcgggactg cgcggagacg gcggtcgggc agtggtcggc
    12961 cgacaccgac atcaccgcgg cgctgcgaga cgtcgtcggc gcgatcaccg cgagaaccct
    13021 gttctcaccg gactttccgg acgacgagcg cagggagctc accggtctga tcgatgcgct
    13081 ggacaaggga gtcgcgctgc gcgtgctgga cccgaccggc ctggccggtc ggctgccgct
    13141 gccggtgaac cggcggttcg aacaggcccg cgcccgcact cacgagctga tggaggcgtt
    13201 catcgcgcgg taccgcgagc gcggcgacga ccggcatgac ctgatgtcca cgctgctggc
    13261 cgcccgcgac gacggccagc tcatgcccga ccggcagatc cgcgacgagg cgatcgccat
    13321 cctgcaggcc ggtttcgaga ccacggcgcg ggcgctgtgc tgggcctgcc acgcgctcgg
    13381 cgaacacccc gagatgcagc gccgggtggg cgacgaggtg tccgaaggtc cgctcggcta
    13441 cgacgacctg ccgcggctgg acctcacccg ccgggtggtc accgaggcgc tgcggctgta
    13501 tccgccgctg tacctgatga cccgccgggc gatcgaggac gtccagatcg gcggtcacac
    13561 cattcccagc ggcagcacgg tgttgttctc gccctacgcc ctgcaccacg atccggcgat
    13621 ctatcccgac ccggagcggt tcgaccccga ccgctggctg ccggacgccc ggcccgagat
    13681 ccagggcgtg acctacctgc cgttcggcgc cggcctgcgc aactgcctgg gcgagcagtt
    13741 cgccatgatg gaactggtgg tcgtgctgag tgcgctgatg cggcggtggt cgctggagcg
    13801 gatccccact gtggccgtgc ggcccaaact gtcgttcgtg ctcgctccca gcgccaccgg
    13861 ggttcggctc agtcttccgg ctgccagcgg tatttccgca tgttgatccg ctggccgtcg
    13921 gccagcacgc cctcggcccg cagccgggcc agctgctcgt gggcgatctg cggggcgggc
    13981 gtgccgttgg cccgcagaat ccggtgccac ggcaggtcgt ggccgtcctc ggagagcatc
    14041 gcgcccacca ttcgcgggct gggggcgccg accatggccg cgatgtcgcc gtaggtcgac
    14101 acccggccgg gcggcacgtc cttgatcgct tcgcgcatcc gctcgtgcaa cgcctcgtcc
    14161 atgcgggcga ttatgcccgc atggacgagg acgcgtgtga ttggctcaca gaccggagca
    14221 ctgcccgatc gccccgccgc gcacggtgtt cggcgcggcg atgttgctcg gtgcgggcgc
    14281 gttcccggca cagctcagcg cgccggtgac cgccacgccg gccaccaccg gctgccgcgc
    14341 gccggtgtgg ttgccggaca acacaagcgc gccgtccacg cgaccgccga cgatcgtcac
    14401 gtcctgcgtg acgccggtga tggacgcggc cccgtgcacg gtggtgtcga gcagttccac
    14461 cgcgttggcg ttgctcgcgc tgacgccacc ggtgatcgtc gagcccgtgg cgaccagtga
    14521 cgcgcccggc gacaccacga tcgcgccggt gacactggcg tggtcgaggc aggtgacgcc
    14581 gtcggtgacc accagcgcgc cgctgtgctg gccggtgatc gtcttggtgc aggccggcgg
    14641 ggccggcagc aggttcacct ggaaactctt ggccgccccg gtgttgccgg ccgcgtcggt
    14701 ggtgcggtac tcgatggtgt gctggccgta gctgggggtc gcatcgtccc aaggggacag
    14761 tcgcggcttg cccagcttgc cgtagacgag atggtcgatc tcggtgccgc tgggcgtgaa
    14821 gtgccacggc tgggtcgagt ccgtgggcca gccgaagtag ttgaaccagc cgtcgccgtc
    14881 ggtgcggaac tcgctgacca gcgagccggt cctgtcgtcg gcggccgtca gccgcatgtc
    14941 gaacggtcca ttgtagacgt actcggaggt gccgtcggcc ttcttgacgc tgagcagggc
    15001 gttggacaac tggtaggagg tggacggatc cgtcgcgtcc acggtccagc tgcgggactt
    15061 gccgccgacc gtggcggtca gcgtgtgcga gccggtcagc ttgaggttct tgaggtccac
    15121 gtcgttggcc gtggtggcca gcgggttgcc gtccagcgcc catcgcaccg gtacgacctg
    15181 gttggtcggg tgtgtggtgt cggcgaacac gacctcgtcc gcgccgatcg ggcggtccgt
    15241 ctcggtggtg tcggcgaagt ccaccgccgt ggtcgtcggc ggcgtcttga ccgccgtgtc
    15301 cacggtccag gtgtgcgtgt tggtcagcgc ctgcttgatc accgggtcac gcacgaaatc
    15361 cgtcgggtcg gtgaccgtcg cggtgagctt gtgcttgccc gccttgaggt tcagcgtccg
    15421 caggtccagc tgctggccgt tcgccgacag cgcttggccg tccaggctcc aggcgatcgt
    15481 gagctggtgg ctgttcgggt gcatcggctc ggcgaacacc acccggtccg cgccgatcgg
    15541 ctgggcggtc ggcgtggtgt cctgcacgat gctggtcttg gccgagatcg acttgaccat
    15601 gtcctcgcgg ccgacctggt cgtagtagta gcccagggtc ttcatgatgg agtgcgcgct
    15661 gggccgccac acgccgctgc tgctgtacat gcccgactcg tagcggccga tcgtgccgcc
    15721 ggcctcgctc ggctcgccca gccagcgcca ccacttcttc tgctgttggg ccatctgctg
    15781 ctcggtgagc agcgtgtggt gcaccgagtc cggctcgccg ccggtgtagg cgtcgccgcg
    15841 cacaccccgg gcgtagtagt catactcgtc ctgcagcccg cccagcgagt gacccagctc
    15901 gtgcggcgtg atcagcgagg acatcgcgtt gccgccggag gccgtcgcgt acgtgccgcc
    15961 gatgccgccg taggtggtgc tgttggcgat gcccaggatc tgccggttgg ccgcggtggt
    16021 gccgggcacg aggttcgcgt acgccgtcgc cgcgttctcg tccatgtaca ggccgcgctg
    16081 cacgccctgc gggtcgcagc ccgaccagaa ctccatgtgc agcggggtgt tccgctgggg
    16141 cgaggtgatg tccgggtcgc agctcacgcc cgacaccgac gacggaatct ccaccgtgta
    16201 gacgttcatg tagttgcggt acgacttgaa cggctcgaag gtgaacagca cattcatgtg
    16261 cttgtccacg tcggcgcgga acttgggcat gtccgcggcc gtgtagccgt cgccgaggat
    16321 caccaggttg aagcgctggg ccgggtcgcc ggtgacccgg atcggcacca ccgtcccggt
    16381 aggggtgtcc gcctgggcgg ccacgggtaa cggcaggagg gccagggccg acgccacgcc
    16441 ggcgatgagg attcgtctca acacccggcc gacgctagga acccggttgt gccgccacaa
    16501 gggccgatgg tcggcttgtg cggccgatag tgtgcccggt tgtgctgacc gccgagatga
    16561 tcgtcgactc ctggatcccg atgaccacgg ccgtgtcgcc ggacggccgc tgggtcgcgt
    16621 acacccagcg gcaggtcggg cggccggtga gcgaggtgtg gctggccggg ggtgaccatc
    16681 cgcctcggcg gctggccgtc gggaccgatc cgcgttggga tcctgactcg ttatccctgt
    16741 gctacctggt cgacggcgtc gaactgcacc ggatcacctt gtccggtacg gacattgtgc
    16801 tggtcaactg gccggccggc atcgacagcc acctgccgct ggtggacggt gtggcgtttg
    16861 tcgccgctga ctcgccggcc ccggagatcg aggtgcggag tgttgtccgg ccgtcccggc
    16921 tgcgtttggc ggactcgtcg ggaatccgtg tcctgtacgg ggatcggcac gtagccgagg
    16981 tcgcgcagca gccaggtggt gggccgctgg ccgtgctcac gtggtccagc cacgaggtcg
    17041 atcccgggct gctctcgccg tcgttgcacg tcgtctcgtt gtcgggggag gtgcgtgacc
    17101 tcgggccggc tgtggtcggc gcgcattcgc ccgtgtggcg tctggtcggc gactggcgtg
    17161 tcgcgtacct cgcgcacacg ccgcccagcc tccagtccgg gactgccgtg tacgacgtcg
    17221 tcgacggcaa cctcaccgcc gggctgccgg cctgcccggt cgaactcgtg cagatggccg
    17281 acggtgaccc gctcgttgtt gtggcttcag ggctggacac ctttgtccgc aggctctccg
    17341 ggccggtggt gtcgcggcac acgggtctgg tggaggcggt cagcgcgggc ggagaatcag
    17401 tggcggcgat cgtcagcacc gctgacgatc cgccggacgt gcatttccgt ggtgtgcggg
    17461 taaccgacct gcggccctgg acccgggaca tcgagtgggg cacccagcgt cggttctcct
    17521 accaggcctc ggacgggctg gagctggaag ggctgctgat cctgccgccg gttggcaccg
    17581 ggccgtttcc gctggtgacc atcgtgcacg gcgggccgta cgaccgcttc gccgaccagt
    17641 tcgggctgca ctgggtcccg tccggacagt ggctcgccct cgccggctac gccgtgttcc
    17701 tgcccaaccc ccgtggcagc cagggccgtg ggcacgaatt cgccaccacc gtcaccggcg
    17761 ccgtcgggca ggaagaatgg accgacatcc tcaccggcat cgacctgctc gtcgccgacg
    17821 gcgtcgcaga tgctgccagg ctcgggatct acggctggag tcacggcggc ttcatggccg
    17881 cctgggccat cggacattcg aatcgcttcg ccgccgccat catgggggcc ggcgtcaccg
    17941 actggggcat gctggtcggc agcggcgaat ggggcatgtt cgaggcttcg ctgggcggta
    18001 gcaccggatg ggaaggtgtc ggcccgcatc gacacgatga gctcagcccc atctcctatg
    18061 cggccaacgt gcgtacgccg gtgcttatcg tgcacggggc ggctgatacc aatgtgccag
    18121 tggctcagtc ggaatacttt caccgggcgc tgcggtatta cggcgttgag cacgagttcg
    18181 tggtctatcc ccgggagggg cactcgtttc gggaacggga gcatcaggtg gatctacacc
    18241 accgggttcg ggagtggttc ggtcggtggt tgtagaggga ggaggctggt tgggcgtggg
    18301 tttggtcgtg tgcccgcgcc gcgcagttgc cgtggatatg gtgtgagggt tttgggtggc
    18361 tccgggtgga ttttgcgcgg agcctctggg cgatggcgta tcgaggcgtc atcgggcagg
    18421 ctgcgcctgc ctcgattcgc ggatcagcgt atgccatcgc ccccctccgc gcaaaatcca
    18481 ccctccgatc cggagtggtg aggggttctt gggggatctg cgctggtttc gctgtggagt
    18541 tgtcaaagaa cgggcggggc gggtgggtca gtattggtgg gggtgggtgg tgtaatggcg
    18601 gcctagtggg gtgcgccagt gcagggttcc gtcttcgtcc agggtggcgg tgtagtcgcc
    18661 gtgtttgagg tggtggtgat gggcgcagta gcccttgagt tgggtggcgt tggtcttgcc
    18721 ctggggccag ggggtggtgt ggtcgagttc ttggatgggg gtggtgcagc cgggtgctga
    18781 gcagactcca cctgcgttga gttcggcgaa ttgcttgatg tcggcggtgg ggcggtactg
    18841 gtctcggctg agttcggagg cacgccggta ttcgtcgagg aggagtccgc gccaggggcc
    18901 gtgcatggcc agttcgcggg cggagtcggc ggcgatgggg ccgtacccgt ccagtaggcc
    18961 ggggtcttcg gtcaacccca ttagggtctc cagggagatg gtgacgtgga ctttgacctt
    19021 gcggtccacc ccgtagccca ggaagcggtc gaggaaggcg tcggcgcgtt tctggtcggt
    19081 ggtgcggtcg tccttgggta gcgagcgggc gtcgcaggtc aggatgtcgt aggcctggcg
    19141 ggcgtcgatg gccggcagga tgatgctgag cttggccatg ccgtcgggca gcggggtgaa
    19201 ctccacccgc cggtcttccc gagccttgag gcaatgccgt tcagataagc ggtctgtgct
    19261 ggtcggtgtg gtgaactgac ggggcgaggg atgaccggta cgttgcccag gcgtgacgtc
    19321 gtctggggtg gagtcgccac cgaggccgca gggccggttg actgaccaca ttggactggg
    19381 tgtgttgtcc gcccggttcg atcgtgacct gatcgaagag gtcctcaacc gcaccgggcg
    19441 gcgggagaga cgcagccggc ggctgcccgc gcacgtgatg atccgctatg tgatcgcgat
    19501 gggcttgttc ttcgccgagt cctacgacga ggtgatgcgc cggttggtcg gcaacctgcg
    19561 caagctcggc tcctgggtcg atgactggca ggtgcccacc aagtcggcga tcacccaggc
    19621 ccgccagcga ctgggaccgc acccggtgaa ggcgctgttc gagcgggcgt gcgtgccgtt
    19681 ggccacctcc gccaccaagg gcgcctggct ggccaggcgc agggtgatgg cgatcgacgc
    19741 gaccagcttc gacgtggccg acacccccga caacgccgag cgcttcggca ggaccggttc
    19801 gggaccaaag gcgtcggctt atccgaagct gcacgtcgcg gcgttggccg aatgcggcag
    19861 tcacgccatc gtcggcgcgg tgctgggctc ggtccggacc ggggaacgta ccctggccgc
    19921 cgacctggcc gcctgggttg gccccgagat gttggtgctg gccgatgccg gcctgtactc
    19981 ctacgagttg ttcggccggt tcgccgccac cggcgccgac ctggcctggc ggatcggcgc
    20041 ctcggtgtcg gtggggcttg tgcggtggct gcctgatggc tcctacctgg ccctgatcta
    20101 ccggtccggg ctcggcgccg agcggcgtgc ccggctggtc gcacaggccc acgccggcca
    20161 ggacatccag gctgacctgg cacggctggt gcgcgtggtc gagtacaccg tcccggaccg
    20221 caaccccgac ggtgagctca tcgtcgtgat caccaccgtg ctggacccgc atgagctgcc
    20281 ggcgctggag ttggccgagg cctaccacca gcgctgggaa gccgaatccg cgctggacga
    20341 gctcaagacc gatctgcgcg gtcgcggtga ggtcctgcgt tccaagactc ctgacctggt
    20401 cgaacaacag atgtggggcc tgctgctggc ccactacgcc atccgcggtc tgctgctgga
    20461 cgccgccgac cccgccggct acgaccccga tcgcatgtcg ttcatcaagg gtcttcgcgt
    20521 ggtccgccgc caggtcaccg accaggcggc cattaccccc tgagtacctg aacgacgctc
    20581 acatcgacgc gatcgaggag atccgccggc actccaaccc accgcgccgc gagcgtgcct
    20641 gcccccgcgc cgtcaaacgc gcccggcaca actcctaccg ggtcaaacgc ctcaccgacg
    20701 agaacatccg ccatcccggc ccggctacgc ctctgctggc ctgcccaaac acccaaactt
    20761 aacggcattg agccttgagg cggcgttggt cgtagccgag agggtcggct tcggcgacgg
    20821 ctttggtggt gcgccgggcc agttgggttc gggtgaggct tggggcgaga tcgaccaggg
    20881 cattctcgac ctgggtgacc agttcgggct tggccaggtg gaccactcga tcgtccacgg
    20941 tctccattcg ccgcaggtcg atctcgccgc gccgcaacag ctccgccatc cgaggcagcc
    21001 ggtcgagcat cgcgctgcgg tgcttctggt gcaccatcga ctgttccggc tcgtgaatgg
    21061 ccatggcgat ctcggcggtg tcctcgacct cgtgcaagag gctgagccgg acgtgatgca
    21121 gagacgcgat ggcccggtga accagaacga gcgcggtgag cttctgctcc tcggtgaggg
    21181 tagctacatt cgcacccaga agcaggtcca caatggcccc cgagggctcc atggattcga
    21241 gctcctgggt gagttctttc atgcctccag aatacgccga ttgaagatcg aactcgaatc
    21301 actaacgggt gaatatgggt cgcaacggaa aggcgcacac aagagccgcg aactctctct
    21361 gtcggagggt ggattttgcg tggagggggc gatggcatac gctgatccgc gaatcgaggc
    21421 aggcgcagcc tgcccgattc ttgcctcgac tgccatcgcc cagaggctcc acgcaaaatc
    21481 cacccggagc cacccagtca attcacctca gtgtcacacc gaagccctct caacgaagat
    21541 caatcaccac tcccgacccc gcccccgccc ccattcacgg caactgcgcg gcgcgggcac
    21601 ccgaccccca cccccgcact ccacgccccc gttacctttt tcgtagctcc tgatcaagga
    21661 gtcgtggtcg ccaggcccgg catgactaac gcccccagtc gaacccatga tccggggggt
    21721 ggtgtcaccg gacctggtgg catcgaagga ccgctgatag ggacacggcc gcccaccggg
    21781 caggtctcgt cgtaacgtgg gtgccggcca tcgatgctcg accggcgacc acacacaacg
    21841 aacggacggc atgacggatg accagcgatt tcggggtgtt cctcggcctg gacgtcggca
    21901 aggacgccca ccacgccgtc ggcctggacc ctgccggcaa gcggctgcac gacgcccccc
    21961 tgcccaacag cgaacccaaa ctccgggcgc tgttcgacaa actcgccacc cacggcccgc
    22021 tgctggtcgt ggtcgaccaa ccagccacga tcggcgcgct gccggtcgcg gtcgcccgcg
    22081 ccgccggcca ccaggtcgcc tacctgcccg gcctggccat gcgccgcatc gccgacctct
    22141 accccggcaa ggccaagacc gacgcccgag atgcgttcat catcgccgac gccgcccgct
    22201 cgctgccgca caccctgcgc ccagtcgacg tcggcgacga cgccctggcc gaactggagg
    22261 tgctggtcgg cttcgacgac gacctggccg gcgaagccac ccgcatcggc aaccgcatcc
    22321 gcggcctgct caccggcatc caccccgcac tcgaacgcgc aatcggcccc aggatcagcc
    22381 acccggccgt gctggagatc ctgtcccgct gcggcggccc caccggaatc cgcgccgccg
    22441 gacgacgcaa aatcaccgct atcgccaccg cgcacgcacc ccgcatgggc gacaaactgg
    22501 tcaccgcgat cctgaccgcg ctggacgagc agacggtcac cgtcccgggc accgccgcag
    22561 ccgacaccgt gctgccccgc ttgg
//
