LOCUS       NZ_CP073318            21224 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Kutzneria sp. CA-103260 chromosome, complete genome.
ACCESSION   NZ_CP073318
VERSION     NZ_CP073318.1
KEYWORDS    RefSeq.
SOURCE      Kutzneria sp. CA-103260
  ORGANISM  Kutzneria sp. CA-103260
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kutzneria.
REFERENCE   1  (bases 1 to 11609901)
  AUTHORS   Jorgensen,T.S., Gren,T., Kontou,E.E., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Complete Genome Sequence of the Rare Actinobacterium Kutzneria sp.
            Strain CA-103260
  JOURNAL   Microbiol Resour Announc 10 (30), e0049921 (2021)
   PUBMED   34323613
REFERENCE   2  (bases 1 to 11609901)
  AUTHORS   Joergensen,T.S., Gren,T., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2021) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-APR-2021
            Assembly Method :: Flye v. 2.8-b1674; unicycler_polish v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 87.0x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:18:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,326
            Genes (coding)                    :: 10,257
            CDSs (with protein)               :: 10,257
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 9 of 69
            Pseudo Genes (incomplete)         :: 63 of 69
            Pseudo Genes (internal stop)      :: 2 of 69
            Pseudo Genes (multiple problems)  :: 5 of 69
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:59:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1349155
            Orig. end                         :: 1370379
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP073318.1.
            Bacteria and source DNA available from Professor Tilmann Weber,
            Technical University of Denmark, Kemitorvet Building 220, room 327D
            2800 Kgs. Lyngby, Denmark.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21224
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21224
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21224
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11224](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11224)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(13..1674)
                     /locus_tag="JJ691_RS05930"
                     /old_locus_tag="JJ691_11850"
     CDS             complement(13..1674)
                     /EC_number="2.2.1.6"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020499475.1"
                     /locus_tag="JJ691_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11850"
                     /product="acetolactate synthase large subunit"
                     /protein_id="WP_211767780.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.6e-49, bitscore:
                     167.0, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-39, bitscore:
                     134.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQPDGRTAADLIVECLLAEGVEVVFGIPGEENMRLTNALDASP
                     IRYVLTRHEQAASFMAEMYGRVTGKAGVVSATLGPGAINLQLGVADATTNSTPLVAISA
                     QVGQFREYKESHQFVDLVSLFAPITQFAGSVPSAAAVPEMLRRAFKTAQSERPGAVYLA
                     VPEDVEVETATPELKPLPLNVVHPEAPSASQVERAAAILRAARNPVLLAGHGAARNHAS
                     AALGRFAEHTGAAVATTFHGKGVLADDHPNSMGTIGFMRRDYANFGFDQADVIVAVGYE
                     LQEFDPVKINPDGDKQIIHIHRFPAEVDAHYSVSVGIEGDISASLDALREAVPAREPHT
                     GAAKIRELVADELARGQRDDRFPLSPQRIVADTRSALGRDDIVLVDTGAVKMWMARLYP
                     TYAANTCLISNGLSTMGFALPGALGVHLARPDRRVLAVTGDGSFLMHSQEIETAVREHL
                     PLTVLVWEDSGYGLIEWKMKLETGTVSNVRFRNPEITQYAASFGATGYHVTQAAELLPT
                     LRKALDDDGVSIVVAPVDYAENISLTDRLGMLTDPL"
     gene            complement(1749..2225)
                     /locus_tag="JJ691_RS05935"
                     /old_locus_tag="JJ691_11860"
     CDS             complement(1749..2225)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="JJ691_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11860"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_211767781.1"
                     /transl_table=11
                     /translation="MQQVTLRKMTAAEYGAATEHREAESVRVLSRVMPEHLARERVRSG
                     TTRFLPDGLDTVGHHLLTAENESGEAVGNAWIGPDPSQASGTASAAWLYDINVFPPYRR
                     LGYGSAILAAAEALVAREGRTALGLNVVGDNEAAIALYRRSGYEVTSMSMRKKM"
     gene            2627..3772
                     /locus_tag="JJ691_RS05940"
                     /old_locus_tag="JJ691_11870"
     CDS             2627..3772
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014741.4"
                     /locus_tag="JJ691_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11870"
                     /product="DUF222 domain-containing protein"
                     /protein_id="WP_211767782.1"
                     /transl_table=11
                     /translation="MKELTRELESREPYGALLDLLMGVDLNALTADQQVTAFIVARKIK
                     AFADHVQLSILSGVEDTAELAMAIHEPEQSVVRQKRSSEVLDRLPRLSELLRRGELDLR
                     RLETVDERIVNLPNPAMIAEVEDALVEVAPGLTRTQLARRATAQVAKVDPTGYDQRRLK
                     AKQDRRVEFTPLPDGMAQLRITLTALDAREVYDVLTQDARALVKDNRTTDQKRADAFVD
                     RFLGYGVDRKVKVHVTISLETLMGLTEDPGLLDGYGPIAADSARELSMHAPWRGLLLDK
                     YRRASELSTDTYRPTARIKEFAELNAGGVCSAPGCTTPIQELDHTVPWPAGDTTATQLK
                     GYCAHHHHLKHGNHTVTLDSDSTLHWVTPLGRHYTTQPHQY"
     gene            complement(4064..5182)
                     /locus_tag="JJ691_RS05945"
                     /old_locus_tag="JJ691_11880"
     CDS             complement(4064..5182)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009945061.1"
                     /locus_tag="JJ691_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11880"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_211767783.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.6e-31,
                     bitscore: 106.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKGAILGSAALAAVSVFRSARTVATWRTVQPLPDTPLDKGRVSV
                     VIPVRDEESTIDGCLASLRTQRHADLEIVVVDDASTDRTAEIVQQHVDDDPRVRLVRTD
                     GPPPGWAGKVHAMFRGVAETTGDWLLFVDSDTESAPDLVGKLLAAAARDNADLITTPGR
                     AIVPNSGWWLLLAPTNVLLFDSASPDGSRGKAVGIGHCILVSRAAYDQAGGWEALSGER
                     ADDVAFATAVRDSGGRTRLVDGMDSITSSGLDSFGAVWRSQRKSIVAGGAMVGGLAAGA
                     AALGLGGLLHLAYGLAPVLMSLRGKGFVRLAGLAAWAAQSAAHRSYMQASHQSATTSVL
                     APAANVTFGVLMLDSAWRSVRGGDLWKGRDIR"
     gene            complement(5205..5426)
                     /locus_tag="JJ691_RS05950"
                     /old_locus_tag="JJ691_11890"
     CDS             complement(5205..5426)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="JJ691_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11890"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_211771305.1"
                     /transl_table=11
                     /translation="MRRRIRVNTISYGALATPMTEHPMLHEWAASNVPMGRVADLAEAA
                     APALFLAGSGSTYMTGAEIAVDGGLTQL"
     gene            complement(5478..6605)
                     /locus_tag="JJ691_RS05955"
                     /old_locus_tag="JJ691_11900"
     CDS             complement(5478..6605)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="JJ691_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11900"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_211767784.1"
                     /transl_table=11
                     /translation="MSDIAILGAGPAGLALARLLHLGGVECAVYERDADQHARTQGGSL
                     DLGADSGLRAITACGLTEEFDRLARPQGQHTNYFDQHGQLLLATDAEDEGEARPEIDRL
                     ELRTMLLESLPAGTVRWNRDVVSVTQTGNRWRITFSDGQHVDADLVVGADGINSRTRPL
                     VTDVPPAYTGVTLIAGEIAKPRLDSYAAELVGEGAGLAFAPDQAFLMQRNGDGSIQVYY
                     AQRRAEDPRRAIGTVLHDPAFIRTELDRELADWSPRMRGVLDEVERHFVWWPLYVVPAR
                     QTWREHSGVTLIGDAAHIMPPYSGQGVNMALLDALELGRALAEHADTDAAIAAYEKSML
                     ARMDPIATATTTYENLVLNPDGPKALLDLVRTGGR"
     gene            6686..7237
                     /locus_tag="JJ691_RS05960"
                     /old_locus_tag="JJ691_11910"
     CDS             6686..7237
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003071458.1"
                     /locus_tag="JJ691_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11910"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_211767785.1"
                     /transl_table=11
                     /translation="MESLRERKKAITRRAIRDAAERLFAERGYDEVTVAEIADAANVSV
                     KTLFVYFRSKEDLVFADTELLDRLIAALAARPADVSHAWVFVDVLAEAAGDGTGLVSYH
                     RAYGESPALRSGLLRMWAEFEDRVVEQLAAESGGPATPAMRLHAIQLVGIVRTTTSPEL
                     RANPDGLADWLREAPSLVEG"
     gene            7291..8403
                     /locus_tag="JJ691_RS05965"
                     /old_locus_tag="JJ691_11920"
     CDS             7291..8403
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012410.4"
                     /locus_tag="JJ691_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11920"
                     /product="ATP-binding protein"
                     /protein_id="WP_249228195.1"
                     /transl_table=11
                     /translation="MPSPTITSAAMDFRGLAGLLSRHLYHDPDVYLRDLLQSAVDAIAA
                     RRRLEPGLSGVVSIEVVEPGELVITDNGIGLTGAELVELLANVGGDSGQYEMVRRRPVR
                     FERDESSRHRDHVGQFGVGLLACFLVADEVTVLTRSAKDPEALRWHGLGDGTYEISPAE
                     SSLPIGTRVHLRARAGVSFGHVSRSARRYGGLLPVPVRMGSTQVNDEPPPWELPALTMD
                     RQRENALGYARRVLDLDPLDAIPLHADGVRGVAFVLPHESSPHRDRVCLRRMLLSESAE
                     RLLPDWAVFVRCVIDADDLLPNVARDGFVEDERLAAVREQLGRCIRDHLVDLARMWPSR
                     LAGIAALHRPALAALAANDGECRRLFDEME"
     gene            8939..9787
                     /locus_tag="JJ691_RS05970"
                     /old_locus_tag="JJ691_11930"
     CDS             8939..9787
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010312040.1"
                     /locus_tag="JJ691_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11930"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_211767787.1"
                     /transl_table=11
                     /translation="MTTTHRARPVLRSDYQRSVAEYWNNEKDPVNLRLGDVDGLYHHHY
                     GLGAYDPAVLDGPDEAVIAEMHRLETAQAEVLLDHLGDVGPEDAVLDAGCGRGGTSIMA
                     NQRFGCYADGITISETQMQFANEQARRRGVSDKVRYHFRNMLDTGFEDASRKAIWNNES
                     TMYVDLHQLFAEHSRQLEIGGRYVTITGCYNDVTGGRSKAVSQIDQHYTCNIHPRSEYF
                     KAMAANKLTPIAVVDLTADTIPYWELRERSSVATGIEGPFLQAYREGSFHYLLIAADRI
                     A"
     gene            complement(10001..11224)
                     /locus_tag="JJ691_RS05975"
                     /old_locus_tag="JJ691_11940"
     CDS             complement(10001..11224)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041167.1"
                     /locus_tag="JJ691_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11940"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_211767788.1"
                     /sec_met_domain="T1TS (E-value: 4.1e-51, bitscore: 173.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLAPSVSGDPAELAAAVLADMRAAPSVELSSLLGGEPERPAP
                     SLLFLTEQPSTLGMSAARLPLLLADRPAEPAPLPPEPAVDDDSDEVPELFCPGPVRDNP
                     ALGEEVNERMVEWAGEVGIYDGRLDHLRSCGFGRLIMLTHPGTDDPDPLLAAAKVVVAE
                     WAADDYYLDEEEMGADPTLAAARLGVLYGVVDPVTMPQRYRHELDRFIKEEPIALAFRT
                     GMEHLAKYTSTAQMGRFQHQMAILFQALDQNASWRQTGKRPAVWEYYMHRYHNSYLPPM
                     ILVDAVAGYELPAQEFYHPRLRRAFTMAGTAAVLLNDLHSMDKEADDDISLPIALMEEE
                     GLSRPQAVKRTVEIHNELMRGFVTEAAAMYLEGTPMLQRFLADTWAWCGGSREWHATSP
                     RYHTQEQS"
     misc_feature    complement(11262..11276)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 22.37"
                     /tool="antismash"
     gene            complement(11339..12235)
                     /gene="bla"
                     /locus_tag="JJ691_RS05980"
                     /old_locus_tag="JJ691_11950"
     CDS             complement(11339..12235)
                     /EC_number="3.5.2.6"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="bla"
                     /gene_functions="resistance (resist) ClassA"
                     /gene_kind="resistance"
                     /inference="COORDINATES: protein motif:HMM:NF033103.1"
                     /locus_tag="JJ691_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11950"
                     /product="class A beta-lactamase"
                     /protein_id="WP_211767789.1"
                     /transl_table=11
                     /translation="MPLPRRTLLFTGLAAALAGCAAKPASEPGTALTLSTTPDADFVAL
                     ERKFGGRLGFYALDTGTGKTVQYRAAERFLMCSTHKVLAVGAILRLRQQQPGLLDRVIH
                     YDQSQVLSYAPITSQHVADGMTVSALCDAALRVSDNTAVNLLIGLLGGPPAVTAFVHDL
                     GETMTHLDRVEPDVNVGAPGDERDTTIPAYFAADLRKVTLGDGLDSAGRDLLVNWMKSA
                     TTGLDLVRAGVPKNWAAADKSGSGAQGEVNDVAVVWPPTGAPLVVTAFTVPTDPKSTAG
                     RATIAEATAIAVKQLGR"
     gene            complement(12285..13031)
                     /locus_tag="JJ691_RS05985"
                     /old_locus_tag="JJ691_11960"
     CDS             complement(12285..13031)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013706.4"
                     /locus_tag="JJ691_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11960"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_211767790.1"
                     /transl_table=11
                     /translation="MTTLATRLHEAQRKAEATPQLPAGITIAEAYAIQHAVLEQRFAAG
                     ERLVGTKLGFTSRAKMVQMGVSDIIVGQLTDAMRVEDGGEVRLSTLVHPRVEPEIIFRL
                     GRDVDPTDPLSDIVSAVDAVAPAVEVIDSRYRDFKFNLADVIADNTSGGLFALGGWQPI
                     GDIGNLAVRLSVNGRDAQFGSTAAILGHPFRALRQLAGIAAREGFPLKAGHVILAGAAT
                     AAVPFGKSVVRVEVAGLGSVTVHGVA"
     gene            complement(13028..14041)
                     /gene="dmpG"
                     /locus_tag="JJ691_RS05990"
                     /old_locus_tag="JJ691_11970"
     CDS             complement(13028..14041)
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154386.1"
                     /locus_tag="JJ691_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11970"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_211767791.1"
                     /sec_met_domain="HMGL-like (E-value: 9.2e-55, bitscore:
                     185.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEIYVQDVTLRDGMHAMAHNYSVAQVREIVTALDAAGVAAIEVA
                     HGDGLGGSSANYGFGAHTDNEWITAAAESVTNAKLTTLLLPGIGTIEDLKHAKDLGVTS
                     VRIATHCTEADISAQHIGWARDNGMDVAGFLMMSHLNEPKKLAEQAKLMESHGAHCVYV
                     TDSGGRLTMRDVAERVDAYGEILEPATQIGIHAHENLSLSVANSVTAVEHGVYRVDVAL
                     AGQGAGAGNCPAEAFIAVADLLGWHHGCDLFALQDAAEDLVRPLQNRPVRVDRETLTLG
                     YAGVYSSFLLHAERAAERYGLDTREILVELGRRRMVGGQEDMIVDVALDLAGKAAS"
     gene            complement(14038..14988)
                     /locus_tag="JJ691_RS05995"
                     /old_locus_tag="JJ691_11980"
     CDS             complement(14038..14988)
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005464749.1"
                     /locus_tag="JJ691_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11980"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_211767792.1"
                     /transl_table=11
                     /translation="MTAGAVVIGSGNIGTDMMFKIKRLSTGLHVAAMAGIDPGSDGLAR
                     ARRLGVATTASGVDGLVELPEFAEARIVFDATSAGAHRHNAEVAAAHGKLMVDLTPAAI
                     GPYVVPSVNLDEHLAADNVNMVTCGGQATIPVVAAVSRTTPVAYAEIVASISSRSAGPG
                     TRANIDEFTETTSAAIQSVGGAARGKAIIVLNPAEPPLVMRDTVYCLVESADHNDAIAE
                     SIDRMVAEVRQYVPGYRLKQDVQFDPVSVPYLPALGGAFDGVKVSTFLEVTGAGHYLPA
                     YAGNLDIMTSAALRTGERIAELRGWLTEPAVGSIA"
     gene            complement(14988..15812)
                     /locus_tag="JJ691_RS06000"
                     /old_locus_tag="JJ691_11990"
     CDS             complement(14988..15812)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020417267.1"
                     /locus_tag="JJ691_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_11990"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_211767793.1"
                     /transl_table=11
                     /translation="MVPRATAIVDLVNPQIQRAADRLKRAAETGQPCAPVRDLIGEHDI
                     DAAYAVQELLTAQRAATTRVVGRKIGLTSDSVRSQFGVYQPDFGTLFADMGYATGEAVP
                     LGRLLQPRVEAEIAFVLGRDIDLSDASVTDVIRATDFVVAAIEIVDSRVDGWDIRITDT
                     VADNASSGLYTLGCTPFSLNGLDLAQVGMVVEHDGEPVSVGSGAACMANPIVAVAWLAR
                     EVARRGAPLRAGEVVLSGALGPMVKVTAPGVFTARLDGLGKVQAVFTDDGGA"
     gene            15820..16575
                     /locus_tag="JJ691_RS06005"
                     /old_locus_tag="JJ691_12000"
     CDS             15820..16575
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226844.1"
                     /locus_tag="JJ691_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12000"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_211767794.1"
                     /transl_table=11
                     /translation="MRSTQRDDGQNSVLGRTVSLLSAFRPDDDRCVTLSELARRSGVAK
                     PTAHRLAMQLVELGMLEPGEGGLRLGLRVFELGQLVPRQRGLRDAARPYLEDLHRASGE
                     TVHLAVLEAPDVVYLDKLTSRAAPAVPSRIGGRMPAHATAVGKALLAHATEEVREIVLS
                     RPLERITPRTVVMRGVLMRELRRVRTEGVAHEYEESANGVVCAACPVVDGQGRAIAAVS
                     VQGWVNRMQIDRVVPALRTTALMLSRQWG"
     gene            complement(16581..17684)
                     /locus_tag="JJ691_RS06010"
                     /old_locus_tag="JJ691_12010"
     CDS             complement(16581..17684)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012335.4"
                     /locus_tag="JJ691_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12010"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_211767795.1"
                     /sec_met_domain="ADH_N (E-value: 5.6e-23, bitscore: 80.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-23, bitscore:
                     82.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKITAAVVEQRHGPFALREVLLDDPRPGEVLVRVVATGICHTDSI
                     TRHGDLPFPLPGVLGHEGAGVVAAVGSGVVGVREGDHVVLGWPWCGECPNCLDGQPRYC
                     LRLKELLVGGGRADGSTALRMPDGTPLSSHFFGQSSFATHAVVPYRGLVTVDPDLPLEL
                     LGPLACGLSTGAGAVLNVLRPHSGASLVVYGVGPVGLAAVMAARNSGATRIIAVDRHPS
                     RLTLARRLGATDVIDAGETDPVAAVHEVCAGPADFSLECTGVIAVCRQAVDSVGMRGVC
                     ALIGGAPADARLELDHLSTLWGKRVVGILGGEGRSSTLIPTLLDLYRQHRFAFDELVTY
                     FPLERISDALAAAETGEVLKPVLRMPS"
     misc_feature    complement(16995..16997)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17681..18505)
                     /locus_tag="JJ691_RS06015"
                     /old_locus_tag="JJ691_12020"
     CDS             complement(17681..18505)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JJ691_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JJ691_12020"
                     /product="hypothetical protein"
                     /protein_id="WP_211767796.1"
                     /transl_table=11
                     /translation="MDLTIRTFRRWLDEADRVLVAAGAGLSAAAGYDYTDTRRFAELFP
                     ALYRQGLRARYQLIGLPLPPQLLWGYWAVHVDDIRFGPGPNPVYQRLRELVGDRDHFVV
                     TSNVDGLFERNGFAPDRVWTPQGDYARYQCEIPCTGSTWESRPIIDTALASYDPGTGTV
                     LDEAVPHCPHCGGDVFLNVHKGPEFIDDHYVPTARRLSRWLDTPSRLLVIEIGAGMNTP
                     TVIRRPTETITRHSPTTRLVRINPEYPDVPTDLAERALSIAAGVEDVLEAMT"
     gene            complement(18496..19356)
                     /locus_tag="JJ691_RS06020"
                     /old_locus_tag="JJ691_12030"
     CDS             complement(18496..19356)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013798.4"
                     /locus_tag="JJ691_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12030"
                     /product="macro domain-containing protein"
                     /protein_id="WP_211767797.1"
                     /transl_table=11
                     /translation="MDTLHALLLSAYREAIALDEPFRPTGAAAPPDRLVQDAARLLGGQ
                     TGETLRDVLPRRAPGPMEPEVAAAVDVLLAAGNSRRAWTDPLTLPTIASVRLDTTYPAA
                     DHTSVWRGDITTLAADAIVNAANSALLGCFLPRHHCVDNAIHSAAGPRLREDCNTIMAA
                     QGAPEPTGTAKITRGYHLPARYVLHTVGPIVTGPVHLADRRALADSYRACLDLAAEVDQ
                     IRTIAFCGVSTGVFGFPKTPAAGIALSTVEGWLSRHPGRFDRVVFTTFGADDLAAYLEQ
                     LTTWT"
     gene            complement(19361..20116)
                     /locus_tag="JJ691_RS06025"
                     /old_locus_tag="JJ691_12040"
     CDS             complement(19361..20116)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.4"
                     /locus_tag="JJ691_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12040"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_249228196.1"
                     /sec_met_domain="PF07366 (E-value: 4.6e-08, bitscore: 32.1,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNKELVLKAAGELFGDRDPSAVDRWVAPDYRQHSSLAADGPEAL
                     RGLVANLPDGFRYELARVVADGDLVALHGVYHGFGPTPLVAFDLFRVENGKLAEHWDGL
                     TPVVATTASGRSQTDGPVDPLATADTEASRALVAEFARRILQDADYSVIPDYISTETYH
                     QHNPEAADGIDGFGAAAAKWAEQGKNLVYKTVHRMIADGDLVLLQSEGEFGEPVAYWDL
                     FRVADGRIVEHWDVIAPIPAELPHRNGIF"
     gene            20218..21102
                     /locus_tag="JJ691_RS06030"
                     /old_locus_tag="JJ691_12050"
     CDS             20218..21102
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /locus_tag="JJ691_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_12050"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_211767799.1"
                     /transl_table=11
                     /translation="MVRSGQDRPLVEFGFSNPDRPRLGVELVDYSLLSSRLPPETLAAV
                     HRTDFHQLFLFRAGEASTMVDFADLHCPAGTLLSVCPGRVLRLPRAVTADVDAVAVLFT
                     VSFPPRLERVRTLLSPFGPVTWSVPAEEWGGIDRAVSELQVEYSRAAAENSTVSTDLVR
                     QLLGALLLRVARLPVAIDHADDGHRSDETFQSFRRELEKDFATTRNAAVYAGRIGYSLR
                     SLNRACQAATGRSAKALIDARVALEAKRMLAHTTLSAAAVGHRLGFSEATNFTKFFVRE
                     TGLTPGAFRADEL"
ORIGIN
        1 ctggtggcgt gatcagagcg gatcggtgag catgcccaga cggtcggtga ggctgatgtt
       61 ctccgcgtag tccacggggg ccacgacgat ggagacgccg tcgtcgtcca gggccttgcg
      121 gagggtgggc agcaactcgg cggcctgggt cacgtggtag ccggtggcgc cgaaactggc
      181 ggcgtactgg gtgatctcgg gattgcggaa ccggacgttg gacacggtgc cggtctccag
      241 cttcatcttc cactcgatca ggccgtagcc gctgtcctcc cacaccagca cggtcagcgg
      301 caggtgctca cgcacggcgg tctcgatctc ctgcgagtgc atgaggaacg agccgtcgcc
      361 ggtcaccgcc agcacccggc ggtcaggtcg ggccagatgc accccgagcg cgccggggag
      421 ggcgaaaccc atggtggaca agccgttgga gatcaggcag gtgttggcgg cgtaggtcgg
      481 gtacagccgc gccatccaca tcttcaccgc gccggtgtcg accagcacga tgtcgtcgcg
      541 gccgagggcg gaccgagtgt cggccacgat ccgctgcggc gacaggggaa accggtcgtc
      601 ccgctggccg cgggccagct cgtcggccac cagctcgcgg atcttggccg ccccggtgtg
      661 gggctcccgc gccggcacgg cctcgcgcag ggcgtccagg gaggcgctga tgtcgccctc
      721 gatgcccacc gacaccgagt agtgcgcgtc cacctcggcc gggaaccggt ggatgtggat
      781 gatctgcttg tcgccgtccg ggttgatctt gaccgggtcg aactcctgga gctcgtagcc
      841 gacggcgacg atcacgtcgg cctggtcgaa gccgaagttg gcgtagtcgc ggcgcatgaa
      901 accgatggtg cccatggagt tcgggtggtc gtcggccagc acgcccttgc catggaaggt
      961 ggtcgcgacg gcggcgccgg tgtgctcggc gaaccggccc agcgcggcgc tcgcgtggtt
     1021 gcgggccgcg ccgtggccgg ccagcagcac cgggttgcgg gccgcccgca ggatggccgc
     1081 ggcccgctcc acctggctgg cggacggggc ctccggatga accacgttga gcggcaacgg
     1141 cttcagctcc ggcgtggccg tctccacctc gacgtcctcg ggcacggcca ggtacaccgc
     1201 gccgggccgc tcgctctgcg ccgtcttgaa cgcgcggcgc agcatctccg gcaccgccgc
     1261 ggccgacggc acactgccgg cgaactgcgt gatcggcgcg aacaggctca ccaggtccac
     1321 gaactggtgc gactccttgt actcgcggaa ctggccgacc tgggccgaga tcgccaccag
     1381 cggcgtcgag ttggtggtcg cgtcggccac gcccagctgg aggttgatcg cccccgggcc
     1441 cagggtcgcc gacaccaccc cggccttgcc ggtgacccgg ccgtacatct cggccatgaa
     1501 cgacgccgcc tgctcgtgcc gggtcagcac gtagcggatc ggcgaggcgt ccagggcgtt
     1561 ggtcagccgc atgttctcct cgccggggat gccgaacacc acctcgacgc cctcggccag
     1621 caggcactcc acgatcagat cggcggccgt ccggccgtca ggctgctgcg acatacctca
     1681 ggcttaccac ttccgcggcg agcggacccg gtggtgagcc ccctttcaca accccgtaag
     1741 ggtcagcgct acatcttctt ccgcatggac atcgacgtca cttcgtagcc actgcggcgg
     1801 tacagggcga tcgccgcctc gttgtccccg acgacgttca ggcccagcgc cgtccggccc
     1861 tcgcgcgcga cgagcgcctc cgcggccgcg aggatcgcgg atccgtaccc gagacgccgg
     1921 tacggcggaa agacattgat gtcatacagc catgcggcgc tcgccgtacc cgaagcctgg
     1981 ctcgggtccg ggccgatcca cgcgttcccc accgcctcgc cggactcgtt ctcggctgtc
     2041 agcagatgat gaccgaccgt gtccaggccg tcggggagga accgcgtggt gccactccgg
     2101 acccgctcac gcgcgaggtg ttccggcatc acccggctga gcacacgcac cgactcggcc
     2161 tcgcgatgct cggtcgcggc accgtactcc gccgccgtca tcttccgtag cgtcacctgc
     2221 tgcacggcca catcctcgat caaccacgtg cgaggacgcc actcggtttc gagccgatgc
     2281 ggtgctgcgg tggatggagt gcctgctcgt cgtggcggta ggggtggttt tggaagggtg
     2341 accggttttt gggttgcggg ggatatggtg ggttttttgg ttgactccgg gtggattttg
     2401 cgtggagcct ctgggcgatg gcaatcgagg caatcatcgg gcaggctgcg cctgcctcga
     2461 ttcgcggacg agcgtacgcc atcgcccccc tccacgcaaa atccaccctc cgaggttaga
     2521 gggagcgatg gttgggtttg tggggtcagg tttgcgatta tgcatgaaac ccggattcac
     2581 ccgttagtga atcgagttcg atctttgagc ggcgtattct ggaggcatga aagaactcac
     2641 ccgagagttg gagagtagag agccttatgg ggccctgctg gatctgctca tgggtgtgga
     2701 cctcaacgct ctgaccgccg atcagcaggt gacggcgttc attgtggcgc ggaagatcaa
     2761 agccttcgcc gatcacgtgc agctgtcgat tctgagcggt gtcgaggaca ctgccgagct
     2821 ggcgatggcc atccatgagc cggagcagtc ggtggtacgg cagaagcgca gtagtgaggt
     2881 gttggaccgg ttgcctcggc tgtcggagct gctacggcga ggagagctgg acctgcggcg
     2941 actggagacc gtagacgagc ggatcgtcaa cctgcccaac cccgccatga tcgccgaggt
     3001 ggaggacgcc ctcgtcgagg tggctccggg gctgacccgc acccaactgg cccgccgggc
     3061 taccgcgcag gtcgcgaagg tcgatcccac cggctacgac cagcgccgcc tgaaggccaa
     3121 acaggaccgt cgggtcgagt tcacaccact cccggacggc atggcccagc tgcggatcac
     3181 cctgaccgcc ttggatgccc gcgaggtcta cgacgtgctg actcaggacg cgcgggccct
     3241 cgtgaaggac aaccggacca ccgatcagaa gcgggccgac gccttcgtgg accggttcct
     3301 gggctatggg gtggaccgca aggtcaaggt gcacgtcacc atctcgctgg agaccctgat
     3361 gggcctgacc gaagaccccg gtctgctgga cggatacggc ccgatcgccg ccgactctgc
     3421 ccgcgagctg tccatgcacg ccccttggcg cggactcctc ctcgacaagt accgtcgggc
     3481 ttccgaactg agcaccgata cctaccgccc caccgcccgc atcaaggaat tcgccgaact
     3541 taatgcaggt ggagtctgct ccgcccctgg ctgcaccacg cccatccaag agttggacca
     3601 caccgttccc tggcccgccg gtgacaccac cgctacccaa ctcaagggct actgcgccca
     3661 tcaccaccac ctcaaacacg gcaaccacac agtcaccctg gattccgaca gcaccctcca
     3721 ctgggtcacc ccactaggcc gccactacac cactcaaccc caccaatact gaccacccga
     3781 tccacccgtt ccttgacaac tccacagcga aaccagccca gcccacccaa gaacccgcaa
     3841 caactcgaat cggagggtgg attttgcgcg gaggggggcg atggcattcg ctgatccgcg
     3901 aatcgaggca ggcggagcct gcccgatgac gcctcgatac gccatcgccc agaggctccg
     3961 cgcaaaatcc acccggagcc acctgaaatc cgctacccac ctgacccaag caaacgagcc
     4021 tgcctccccc accggcccgc aacccaccac ggcccccgag ccgctaccga atgtcccgcc
     4081 ccttccacag atcgccacca cgcaccgagc gccacgcgga gtccagcatc agcacgccga
     4141 acgtgacgtt ggcggccggg gccagcaccg aggtggtggc ggactggtgg ctggcctgca
     4201 tgtacgagcg gtgggcggcg gactgggcgg cccaggcggc gagaccggcc aagcggacga
     4261 agcccttgcc ccgcaaggac atcaacaccg gggcgaggcc gtaggcgagg tgcagcaggc
     4321 cgccgaggcc cagcgcggcg gccccggcgg cgaggccgcc gaccatggcc ccgccggcga
     4381 caatgctctt gcgctgggac cgccagaccg cgccgaacga gtccaggccg gacgaggtga
     4441 tcgagtccat gccgtccacg agccgggtgc ggccgccgct gtcccgcacg gcggtggcga
     4501 acgcgacgtc gtcggctcgt tcgccggaca gcgcttccca gccgccggcc tggtcgtagg
     4561 cggcccggct gaccaggatg cagtgcccga tgccgacggc cttgccccgg ctgccgtccg
     4621 gcgacgcgct gtcgaacagc agcacgttgg tcggggccag cagcagccac cagccgctgt
     4681 tgggcacgat cgcccggccc ggcgtggtga tcaggtcggc gttgtcccgg gccgccgcgg
     4741 ccagcagctt gccgaccagg tcgggggcgg actcggtgtc ggagtcgacg aacagcagcc
     4801 agtcgccggt ggtctcggcg acgccccgga acatggcgtg caccttgccg gcccagcccg
     4861 gcggcggccc gtcggtgcgg accagccgca ctcgcggatc gtcgtccacg tgctgctgca
     4921 cgatttccgc ggtccggtcg gtcgaggcgt cgtcgaccac cacgatctcc aggtcggcgt
     4981 gccgctgggt acgcagcgag gccagacagc cgtcgatggt ggactcctcg tcgcgcaccg
     5041 ggatcacgac gctgaccctg cccttgtcca gcggggtgtc cggcagcggc tgaaccgtcc
     5101 gccaggtcgc caccgtgcgc gccgagcgga acaccgagac cgccgccaac gccgccgaac
     5161 cgagaatcgc ccccttgccc atgccctcca ggctgccaca gtcgtcagag ctgggtgagg
     5221 ccgccgtcca cggcgatctc cgcgcccgtc atgtacgtcg accccgatcc ggccaggaac
     5281 aacgccggcg cggccgcctc ggccaggtcg gcgacccgcc ccatcgggac gttcgatgcg
     5341 gcccactcgt gcagcatcgg gtgctcggtc atcggcgtgg ccaatgcccc gtagctgatg
     5401 gtgttgaccc ggatccgacg gcgcaggaac tggagccgcc ggtgatcacg gcggtcctgc
     5461 ccttgagcgc gtccatgtca gcgacctccg gtccgcacga ggtcgagcag cgccttgggc
     5521 ccgtccgggt tgagcaccag gttctcgtac gtcgtcgtgg ccgtcgcgat tggatccatt
     5581 cgggccagca tcgacttctc gtaggcggcg atcgccgcgt cggtgtccgc gtgctcggcg
     5641 agcgctcgcc ccagctccag ggcatcgagc agcgccatgt tcacgccctg tccggagtac
     5701 ggcggcatga tgtgcgcggc gtcgccgatc aacgtgacac cggagtgctc gcgccaggtc
     5761 tgacgggccg gcaccacata cagcggccac cacacgaagt gcctctcgac ctcgtccagg
     5821 actccgcgca ttcggggcga ccagtcggcc agctcccggt ccagttcggt gcggatgaac
     5881 gccggatcgt gcagcacggt gccgatcgcc cggcgcgggt cctcggcccg gcgctgcgcg
     5941 tagtacacct ggatcgagcc gtctccgttg cgctgcatga gaaacgcttg atcgggcgcg
     6001 aaggcgaggc cggcgccttc accgacgagt tcggcggcgt aggagtcgag ccgtggcttg
     6061 gcgatctcgc cggcgatcag cgtcaccccg gtgtaggccg gcggcacgtc ggtgaccagc
     6121 gggcgggtgc gggagttgat gccgtccgca ccgaccacca ggtcggcgtc gacgtgctgg
     6181 ccgtcggaaa acgttatccg ccaacggttt cctgtctggg tgacggagac gacgtcacgg
     6241 ttccagcgca cggtgccggc gggcagcgac tccagcagca tcgtgcgcag ctccaggcgg
     6301 tcgatctccg gccgtgcctc gccctcgtcc tcggcgtcgg tcgccagcag gagctggccg
     6361 tgctggtcga agtagttggt gtgctggccc tggggccgcg cgagccggtc gaactcctcg
     6421 gtcagcccgc aggcggtgat cgcccgcaga ccgctgtccg cgcccagatc cagcgaaccg
     6481 ccctgggtgc gggcgtgctg gtcggcgtcc cgctcgtaga cggcgcactc gacgccgccc
     6541 aggtgcagca gccgcgcgag ggccaggccg gccgggccgg cgcccaggat cgcgatgtcg
     6601 gacacggtgt cctcctcccg ttgggtaact cgctagaaaa ggtaagtcgc ttaccttcgt
     6661 gcgtcaagga ggtatgatct cggtcatgga gtcgctgcgc gaacggaaga aggcgatcac
     6721 ccggcgggcc atccgggacg ccgccgagcg gctgttcgcc gagcgcggct acgacgaggt
     6781 gaccgtggcc gagatcgccg acgccgccaa cgtctcggtg aagacgctgt tcgtctactt
     6841 ccggtccaaa gaggacctgg tgttcgccga caccgagctg ctggaccggc tgatcgccgc
     6901 gctggccgcc cggcccgccg acgtcagcca cgcctgggtc ttcgtcgacg tgctggccga
     6961 ggccgccggc gacggcaccg gcctggtgag ctaccaccgc gcctacggcg agtcgcccgc
     7021 gctgcgctcc ggcctgctgc ggatgtgggc cgagttcgag gaccgcgtcg tcgaacagct
     7081 cgccgccgag tccggcgggc ccgcgacccc ggccatgcgg ctgcacgcca tccagctcgt
     7141 cgggatcgtg cgcacgacga cgtccccgga gctccgcgcc aaccccgacg gcctggccga
     7201 ctggctccgg gaggcgccgt ccctggtcga aggctagggg tttgcccgat gctagggggc
     7261 ggcccggcgt tccagaatcg ccgcgtgcgc atgccgtctc cgacgatcac ctcggccgcg
     7321 atggactttc gcggcctggc cggtttgctg tcgcggcacc tctaccacga cccggacgtc
     7381 tacctccggg acctgctcca gagcgccgtc gacgcgatcg ccgcgcgtcg acggctggag
     7441 cccggcctgt ccggggttgt gtcgatcgag gtggtcgaac ccggcgagct cgtgatcacc
     7501 gacaacggca tcggcctgac cggtgccgag ctggtcgagc tcctggccaa tgtcggcggc
     7561 gattcggggc agtacgaaat ggtgcgacgg cgtccagtcc gcttcgagcg ggatgagtcg
     7621 tcccggcatc gggaccatgt cggccagttc ggcgtcgggc tgctcgcgtg cttcctggtc
     7681 gccgacgagg tcaccgtgct cactcggtcc gcgaaggatc cggaagcgct ccggtggcat
     7741 gggcttggtg acggcaccta tgagatcagc ccggcggaga gttctctccc gataggcact
     7801 cgggtacacc tgcgggcccg ggctggcgtc tcgttcggcc atgtgtcgcg atcggcccgt
     7861 cgctacggcg gcctgctgcc ggtgccggtc cggatggggt cgacgcaggt caacgatgag
     7921 ccgccgccat gggagctgcc ggcgctgacc atggaccggc agcgggagaa cgccctcggg
     7981 tacgcccgcc gggtgctgga cctggatcca ttggacgcga tcccgctgca tgccgacggc
     8041 gtccgcggag tggcgttcgt gctgccacac gagtcgagcc cgcaccgcga ccgggtgtgc
     8101 ctgcggcgta tgttgctttc cgagtcggct gagcgattgc tgccggattg ggcggttttc
     8161 gtgcgctgcg tgatcgacgc cgacgatctg ctccccaacg tggcccggga cggcttcgtc
     8221 gaggacgagc ggctggcggc cgtccgtgag cagctgggcc gatgcatccg ggaccacctc
     8281 gtggacctgg cccggatgtg gccctcgcgc ctggccggca tcgccgccct gcatcgcccc
     8341 gccctcgcgg ctctggccgc gaacgacggt gaatgccggc ggttgttcga cgagatggaa
     8401 tgaccggcac ttcccgcgcc tacttgatac ggcagacggg ggcaccgccg taggagtgaa
     8461 cgacgctgag tggcactggg gccggaccat gccccttgag ccgttggtgc gactcggccg
     8521 tctggatgac acatgctcgg ggagcggcga ctcgcggccg cggcgtggcc ggcgtggtcg
     8581 cgccgccgat ggcctgcggg aatcggcttt tcgttggcag acaacaccac cgtccgagct
     8641 ggacgatcgg cggcagcgga tttccctttc tgagcaacga tcatccgatg gcgcacgtcc
     8701 gggttatcgg gcatcacccg cacggagcaa cgagttctac gcagcgcatg tccacaacgg
     8761 agcagcggca caccaccctg ttgagggact gtgttggtcc ggaaagccgg tgctagcctc
     8821 ggctgggccg gccggccacc gcgtttcccc gcgttcgtcg ccaccagcga cgccgggaag
     8881 tccttatctg ccaccgatta tcgatggcgc acgtccgcac ggttgaagga gttcgcgcat
     8941 gacgacaacc caccgcgcac ggccggtcct ccgcagcgac taccagcgtt cggtcgctga
     9001 gtactggaac aacgagaagg acccggtcaa cctgcggctc ggtgatgtcg acggcctcta
     9061 ccaccaccac tacgggctcg gcgcctacga cccggccgtg ctggacggtc cggacgaggc
     9121 cgtcatcgcg gagatgcacc gcctggagac agcgcaggcc gaggtcctgc tggaccacct
     9181 cggcgacgtc ggtcccgagg acgcggtgct ggacgccggc tgcggtcgcg gcggcaccag
     9241 catcatggcc aaccagcggt tcggctgcta cgcggacggc atcaccattt ccgagacgca
     9301 gatgcagttc gccaacgagc aggcccgccg ccgcggcgtc tcggacaagg tgcgctacca
     9361 cttccggaac atgctcgaca ccggcttcga ggacgcgagc cgcaaggcga tctggaacaa
     9421 cgagagcacc atgtacgtcg acctgcacca gctgttcgcc gagcactcgc ggcagctgga
     9481 gatcggcggc cgctacgtga cgatcaccgg atgctacaac gacgtcaccg gcggccggtc
     9541 caaggcggtc agccagatcg accagcacta cacctgcaac atccacccgc gcagcgagta
     9601 cttcaaggcc atggcggcca acaagctcac gccgatcgcg gtggtcgacc tgaccgccga
     9661 caccatcccc tactgggaac tgcgcgagcg ctcctcggtc gccaccggca tcgagggccc
     9721 gttcctgcag gcctaccggg agggcagctt ccactacctg ctcatcgccg ccgaccgaat
     9781 cgcctagccg gcaacgcttt ccccgaggcc cgcgtccacc gaggacgcgg gcctccgcgg
     9841 cgttccgccg agatcgacgc cccccaagat caaggctccg atcctctcgt tcaacgtcat
     9901 gaaggacccc ttcacgacgt tgaacgagag gaaggggccc ttcatgacag aagcaggggc
     9961 cccgcacctg gaaacggtgc ggggcccggg gttcgtccga tcaggactgc tcttgcgtgt
    10021 ggtagcgcgg gctggtggcg tgccactcgc ggctgccccc gcaccaggcc caggtgtcgg
    10081 ccaggaagcg ttgcagcatc ggggttccct cgaggtacat cgcggcggcc tcggtgacga
    10141 agccgcgcat gagctcgttg tggatctcga cggtgcgctt gacggcctgc ggccgggaca
    10201 ggccctcctc ctccatcagc gcgatgggca ggctgatgtc gtcgtcggct tccttgtcca
    10261 tcgagtgcag gtcgttgagc agcacggcgg ccgtgccggc catggtgaag gcccggcgca
    10321 ggcgggggtg gtagaactcc tgggccggca gctcgtagcc ggcgacggcg tcgaccagga
    10381 tcatcggcgg cagatagctg ttgtggtagc ggtgcatgta gtactcccac accgcgggcc
    10441 gcttgccggt ttggcgccag ctggcgttct ggtccagggc ctggaacaga atggccatct
    10501 ggtgctggaa acggcccatc tgagcggtgc tggtgtactt ggccaggtgt tccatgccgg
    10561 tgcggaaggc cagcgcgatg ggctcttcct tgatgaagcg gtcgagctca tggcggtagc
    10621 gctgcggcat cgtcacggga tcgacgacac cgtacaggac gccgaggcgg gcagcggcca
    10681 gcgtgggatc cgcgcccatc tcctcctcgt ccaggtagta gtcgtcggcc gcccattcgg
    10741 cgacgaccac cttggcggcg gccagcagcg ggtccgggtc gtcggtgccg gggtgggtga
    10801 gcatgatcag ccggccgaag ccgcaggacc gcaggtggtc cagccggccg tcgtagatgc
    10861 cgacctcgcc ggcccactcc accatgcgct cgttgacttc ctcgccgagc gccggattgt
    10921 cccgcaccgg gccggggcag aacagctccg gcacctcgtc ggagtcgtcg tcgacggccg
    10981 gttccggcgg cagcggcgcg ggctcggccg gccgatcggc cagcagcagt ggcaaccggg
    11041 ccgcggacat gcccagcgtg gagggttgct cggtgaggaa cagcaggctg ggggccgggc
    11101 gctccggttc gccgccgagc agcgacgaca gctccaccga cggcgccgcc cgcatgtcgg
    11161 ccagcaccgc cgccgccagc tccgctgggt ctccggacac gctcggggca agaagccgag
    11221 acatcaggga catgcggcca gtaagccaca aaccacggcg ctggaacgga aagtccactc
    11281 ggatgtgcta cgggtcgggt ggctggatac cgccagaagt gcggtgcttc aaggaaattc
    11341 agcgccccag ctgcttcaca gcgatggcgg tcgcctcggc gattgtggca cgaccagcgg
    11401 tggacttggg atcggtcggc acggtgaacg cggtgacgac caggggagcg ccagtgggcg
    11461 gccagaccac ggcgacgtcg ttgacctcgc cctgcgcgcc actgccggat ttgtcggctg
    11521 ccgcccagtt cttgggcacc ccggcccgga ccaggtccag accggtggtg gccgacttca
    11581 tccagttcac gagcaggtcg cggccggcgc tgtcaagacc gtcacccaat gtcactttcc
    11641 gcaggtcggc ggcgaaatac gccgggatgg tggtgtcccg ctcgtcgccg ggcgcgccga
    11701 cgttgacatc gggctccacc cggtccaggt gggtcatggt ctcacccagg tcgtggacga
    11761 aggccgtgac cgcgggcggg ccgccgagca gaccgatcag caggttgacg gccgtgttgt
    11821 cgctgacccg cagcgccgcg tcgcacaggg ccgacaccgt catgccgtcg gcgacgtgct
    11881 gcgaggtgat cggcgcgtag gacaggacct gggactggtc gtagtggatg acccggtcga
    11941 gcagaccggg ctgttgctgg cgcagccgga gaatcgcgcc gacggcgagc accttgtgcg
    12001 tggagcacat gaggaaccgc tcggcggcgc gatactgcac ggtcttgccg gtgccggtgt
    12061 cgagcgcgta gaacccgagc cggccgccga acttccgttc cagggcgacg aaatccgcgt
    12121 cgggagtcgt cgacagcgtc aaggccgtcc ccggctcgct cgccggcttg gcggcacagc
    12181 cggcgagcgc ggcggcgagc ccggtgaaca gcagagtgcg gcgcggcaac ggcatgtgtg
    12241 aacccccagg gtgtgtatct gagggtcaca ctacccgtgg cgagtcaggc gacgccgtgc
    12301 accgtgacgc tgcccaggcc ggcgacctcg accctgacca ccgactttcc gaacggcacg
    12361 gccgcagtcg cggcgccggc caggatgaca tgtccggcct tcaagggaaa tccctcacga
    12421 gcggcgatgc cggccagctg ccgcagcgcc cggaacggat gcccgagaat ggcggcggtt
    12481 gagccgaact gcgcgtcccg accgttcacg ctgagccgca cggcgaggtt gccgatgtcg
    12541 ccgatcggct gccagccgcc gagcgcgaac aaaccgccgg aggtgttgtc ggcgatcacg
    12601 tcggccaggt tgaacttgaa gtcccggtag cgggaatcga tgacctcgac cgccggcgcg
    12661 acggcgtcca ccgcggacac gatgtccgac aacgggtccg tgggatccac gtcccgcccg
    12721 agccggaaga tgatctccgg ctcgacccgg gggtgcacca gcgtggacag ccgcacctcg
    12781 ccgccgtcct cgacccgcat ggcgtcggtc agctggccga cgatgatgtc ggagacgccc
    12841 atctgcacca tcttcgcccg gctggtgaag ccgagcttgg tgccgaccag gcgctccccg
    12901 gcggcgaagc gctgctccag cacggcatgc tggatggcgt aggcctcggc gatggtgatg
    12961 cccgccggca gttggggagt ggcctcggcc ttgcgctggg cctcgtgcag ccgcgttgcc
    13021 agggtcgtca cgacgccgcc ttgccggcga gatcgagcgc gacgtccacg atcatgtcct
    13081 cctgcccgcc gaccatccgg cgccggccca gctccaccaa aatctcccgg gtgtccagac
    13141 cgtaccgttc ggccgcccgc tcggcgtgca gcaggaaact ggagtacaca ccggcatagc
    13201 ccagcgtcag cgtctcccgg tcgacgcgga cgggccggtt ctgcaacggt cgcaccagat
    13261 cctcggcggc gtcctgaagt gcgaacaggt cgcaaccatg gtgccagcca agcagatccg
    13321 cgacggcgat gaacgcctcg gccgggcagt tgccggcccc cgcgccctga ccggccagcg
    13381 cgacgtccac ccggtacaca ccgtgctcga cggcggtcac gctgttggcc accgacagcg
    13441 acaggttctc gtgcgcgtgg atgccgatct gcgttgccgg ttccaggatt tcgccgtagg
    13501 cgtcgacccg ctcggcgacg tcccgcatgg tcagccggcc gccggagtcg gtgacgtaga
    13561 cgcagtgggc gccgtgggac tccatcagct tggcctgctc ggccagcttc ttcggttcgt
    13621 tgaggtggct catcatcagg aagccggcga cgtccatgcc gttgtcccgg gcccagccga
    13681 tgtgctgcgc ggagatgtcg gcctcggtgc agtgggtggc gatccgcacg ctggtcacgc
    13741 cgagatcctt ggcgtgcttg aggtcttcga tggtgccgat gcccggcagc agcagcgtgg
    13801 tcagcttggc gttggtcacc gactcggcgg cggcggtgat ccactcgttg tcggtgtggg
    13861 cgccgaagcc gtagttggcg ctggaaccgc cgaggccgtc gccgtgggcc acctcgatgg
    13921 cggccacgcc ggcggcgtcc agcgcggtga cgatctcccg cacctgcgcg acggagtagt
    13981 tgtgcgccat ggcgtgcatg ccgtcgcgaa gggtcacgtc ctgaacgtag atctcggtca
    14041 tgcgatgctc cccaccgcgg gctcggtcag ccagccccgc agctcggcga tgcgctcgcc
    14101 ggtccgcagc gcggccgagg tcatgatgtc gaggttgccg gcgtaggcgg gcaggtagtg
    14161 gccggccccg gtgacctcca ggaaggtcga gaccttgacg ccgtcgaacg cgccacccag
    14221 ggccggcagg tacggcacgg agaccgggtc gaactgcacg tcctgcttga gccggtagcc
    14281 gggcacgtac tgccgcacct cggcgaccat gcggtcgatc gactcggcga tggcgtcgtt
    14341 gtggtcggcc gactccacca ggcagtagac ggtgtcccgc atgaccagcg gcggttcggc
    14401 cgggttcagc acgatgatcg ccttgccacg ggccgcgccg ccgaccgact ggatggccgc
    14461 cgacgtggtc tcggtgaact cgtcgatgtt ggcccgggtg ccggggccgg ccgacctgga
    14521 cgagatggag gcgacgattt ccgcgtaggc caccggcgtg gtgcgggaaa ccgcggcgac
    14581 gacgggaatt gtggcctggc cgccgcaggt gaccatgttg acgttgtcgg cggccaggtg
    14641 ctcgtccagg ttcaccgacg gcaccacgta cgggccgatc gccgccggag tcaggtccac
    14701 catcagtttg ccgtgcgcgg ccgcgacttc cgcgttgtgc cggtgcgcgc cggccgaggt
    14761 ggcgtcgaag acgatgcgcg cctcggcgaa ctccggcagc tcgaccagac cgtccacacc
    14821 ggacgccgtg gtggccacgc cgagccgccg ggcccgggcc aggccgtcgg aacccgggtc
    14881 gatgccggcc atggcggcca cgtgcaggcc ggtcgacagc cgcttgatct tgaacatcat
    14941 gtcggtgccg atgttgccgg aaccgatcac caccgctccc gcggtcatca cgcacctccg
    15001 tcgtcggtga acacggcttg gaccttgccc agaccgtcca ggcgggcggt gaagaccccc
    15061 ggggcggtga ccttgaccat ggggcccagc gcgccggaca gcaccacctc gccggcccgc
    15121 agcggtgcgc cgcgccgggc cacttcccgg gccagccagg cgaccgcgac gatcgggttg
    15181 gccatgcagg cggcccccga gccgaccgag accggctcgc cgtcgtgttc cacgaccatg
    15241 ccgacctggg cgaggtcgag gccgttgagg gagaacgggg tgcagccgag ggtgtagagc
    15301 ccgctggacg cgttgtcggc caccgtgtcg gtgatgcgga tgtcccaacc gtccactcgg
    15361 gagtccacga tctcgatggc cgcgacgacg aagtcggtgg cccggatgac atccgtgacc
    15421 gacgcgtccg acagatcgat gtcgcggccg agaacgaagg cgatctccgc ttcgacccgc
    15481 ggctggagca ggcggccgag cgggaccgct tcgccggtgg cgtagcccat gtccgcgaac
    15541 agcgtgccga agtccggctg gtagacgccg aactggctgc ggaccgagtc tgaggtgagg
    15601 ccgatcttgc ggcccacgac gcgggtcgtg gcggcccgct gggccgtgag cagctcctgc
    15661 acggcgtagg cggcgtcgat gtcgtgctcg ccgatgaggt cgcggaccgg ggcacacggc
    15721 tggcccgtct ccgccgcccg cttcaggcgg tcggccgctc gctggatctg ggggttcacg
    15781 aggtcgacga tggcggtcgc acgtggcacc atgccagcta tgcgttccac tcagcgagac
    15841 gacggtcaga actcggtgct gggccggacg gtttccctgc tgtcggcctt ccgtccggac
    15901 gacgaccggt gcgtgacgct gtccgaactg gcccggcgct cgggggtggc caagccgacc
    15961 gcgcaccggc tggccatgca gctggtggag ctgggcatgc tggagccggg ggagggcggg
    16021 ctcaggttgg ggctgcgggt gttcgagctg gggcagctgg tgccgcggca gcggggtctg
    16081 cgggacgcgg cgcggccgta cctggaggac ctgcaccggg cgtcggggga gaccgtgcac
    16141 ctcgccgtgc tggaagcgcc ggatgtcgtg tacctcgaca agctcaccag ccgcgccgcc
    16201 ccggccgtgc cgtcccgtat cggcggccgg atgcccgccc acgccactgc cgtaggcaag
    16261 gcgctgctgg cccatgccac cgaggaagtg cgggaaatcg tgctgtcacg gccgttggag
    16321 cgcatcacgc cccggaccgt ggttatgcgc ggggtgttga tgcgggaact ccggagggtg
    16381 cgaaccgaag gcgtggcgca cgagtacgag gaatcggcca acggcgtggt gtgcgcggcc
    16441 tgccccgtgg tggacgggca gggccgggcg atcgccgcgg tgtcggtgca gggctgggtg
    16501 aaccggatgc agatcgaccg ggtggtgccg gcgctgcgaa ccacggcgtt gatgctgtca
    16561 cggcagtggg ggtgagatgc tcaggagggc atgcgcagca ccggcttgag gacctcgccg
    16621 gtctcagcgg cggcgagcgc gtcactgatc cgttcgagcg ggaagtaggt cacgagttcg
    16681 tcgaaggcga accggtgctg gcggtacagg tcgagcaacg tggggatcag cgtcgagctc
    16741 cggccttcgc caccgaggat gccgacgacc cgtttgcccc acagggtgct gaggtggtcc
    16801 agttcgagcc gcgcgtcggc gggtgcgccg ccgatgaggg cgcagacacc ccgcatgccg
    16861 acggagtcca cggcttgtcg gcacacggcg atgactccgg tgcactccag gctgaaatca
    16921 gcgggcccgg cgcagacctc gtgcaccgcg gcgacggggt cggtctcgcc ggcgtcgatg
    16981 acgtcggtgg cgcctaacct gcgcgcgagg gtgagccgcg acgggtgtcg gtccacggcg
    17041 atgatcctgg tggcgccgct gttgcgggcg gccatgacgg cggccagccc gaccgggccg
    17101 acaccgtaga cgacgaggct ggcgccgctg tgcgggcgca gcacgttgag cacggccccg
    17161 gcacccgtgg agagcccgca tgccaacggt ccgagcaatt ccagtggcag atcgggatcg
    17221 acggtcacga ggcctcggta gggcaccaca gcgtgcgtgg cgaacgacga ctgcccgaag
    17281 aagtggctcg acaacggtgt gccgtcgggc atgcgcagcg cggtggaacc gtccgcacga
    17341 ccaccgccga cgagaagttc cttcaaccgc aggcaatagc gaggctggcc gtcgagacag
    17401 ttcgggcatt caccacacca cggccagccc agcacgacgt gatccccctc gcggacacca
    17461 accacaccgg acccgacggc ggccaccaca cccgccccct cgtgcccgag cacgccgggc
    17521 agcgggaacg ggaggtcgcc gtgccgcgtg atggaatcgg tgtggcagat tccggtcgcg
    17581 accacgcgga ccagcacctc gccgggccgg ggatcgtcca gcagcacctc cctcagtgcg
    17641 aacggtccgt gccgctgctc gacaacggcg gccgtgatct tcatgtcatc gcctccagca
    17701 cgtcctcgac gccggcggcg atggacagcg cccgctcggc caggtcggtg ggcacgtcgg
    17761 gatactcggg gttgatccgc accagtcggg tggtcggcga gtggcgggtg atggtctcgg
    17821 tgggccggcg gatcacggtc ggagtgttca tgcccgcgcc gatctcgatg accagcagcc
    17881 gggacggggt gtccagccac cggctcaggc gccgcgcggt cgggacgtag tggtcgtcga
    17941 tgaactccgg tcccttgtgc acgttgagga acacgtcgcc gccgcagtgg ggacagtgcg
    18001 gcacggcttc gtccaggacg gtgccggtgc ccgggtcgta actggccagc gcggtgtcga
    18061 tgatcggtcg gctctcccag gtactgccgg tgcacgggat ctcgcactgg tagcgggcgt
    18121 agtccccctg cggggtccac acccggtccg gcgcgaaacc gtttcgctcg aacagtccgt
    18181 ccacattgga cgtgacaacg aagtgatccc ggtcgccgac gagctcgcgc agccgctggt
    18241 agaccgggtt ggggccggga ccgaaccgga tgtcgtcgac gtggacggcc cagtatcccc
    18301 acagcagttg tggcggcagc ggcagtccga tcagctggta ccgggcccgg aggccctggc
    18361 ggtacagggc agggaacagc tcggcgaacc ggcgggtgtc ggtgtagtcg tagccggctg
    18421 ccgccgacag ccccgcgccg gcggcgacga gcacgcgatc ggcctcgtcg agccaccggc
    18481 ggaaggtgcg gatcgtcagg tccatgtcgt caactgctcc aggtacgcgg cgaggtcgtc
    18541 ggcgccgaac gtggtgaaca cgacgcggtc gaatcgacca ggatgccgac tcaaccagcc
    18601 ctccactgtg gacagtgcga tccccgcggc gggtgtcttg gggaatccga agacaccggt
    18661 gctgacgccg cagaacgcga tcgtgcggat ctggtccacc tcggccgcca ggtccaggca
    18721 ggcccgatag gagtcggcca acgcccgccg gtcggccaga tggaccggcc cggtcacgat
    18781 cggacccact gtatggagga cgtagcgtgc gggcaggtgg tagccccggg tgatcttggc
    18841 ggtgccggtc ggctcgggcg cgccctgggc ggccatgatc gtgttgcagt cctcgcgcag
    18901 ccgggggccg gcggcgctgt ggatggcgtt gtcgacacag tggtgcctcg gcaggaaaca
    18961 gcccagcagg gcgctgttgg cggcgttgac gatcgcgtcg gcggccagcg tggtgatgtc
    19021 gcctcgccac accgacgtgt gatccgcggc cgggtaggtc gtgtccagcc gaacactggc
    19081 gatcgtgggc agggtcagcg ggtccgtcca ggcccgccgg gagtttcccg cggccagcaa
    19141 tacgtccacg gcggcggcga cctccggctc catcggaccg ggcgcgcgac ggggcagcac
    19201 gtcccgcagc gtctccccgg tctggccgcc gagcagccgc gccgcgtcct ggacgagccg
    19261 gtccggcggg gcagccgccc cggtcggtcg gaacggctcg tccagtgcga tcgcctcgcg
    19321 gtacgcgctc agcagcaacg cgtgcagggt gtccatcagc tcagaagatg ccgttgcggt
    19381 gcggcaactc ggcggggatc ggcgcgatga cgtcccagtg ctcgacgatg cggccgtcgg
    19441 ccacccggaa cagatcccag tacgccaccg gttcgccgaa ctcgccctcg gactggagca
    19501 gcaccaggtc gccgtcggcg atcatccggt gcacggtctt gtagaccagg ttcttgccct
    19561 gctcggccca cttcgcggcg gcggcgccga agccgtcgat cccgtcggcg gcctcggggt
    19621 tgtgctggtg gtacgtctcg gtcgagatgt agtcggggat cacggagtag tcggcgtcct
    19681 ggaggatccg ccgggcgaac tcggcgacca gggcgcggct ggcctcggtg tccgccgtgg
    19741 ccagggggtc gaccggcccg tcggtctgcg accggccgct ggccgtggtg gccaccaccg
    19801 gcgtgaggcc gtcccagtgc tcggccagct tgccgttctc gacgcggaac aggtcgaacg
    19861 ccaccaaggg ggtgggcccg aagccgtggt agacgccgtg cagcgcgacc aggtcgccgt
    19921 cggcgacgac ccgcgcgagt tcgtagcgga agccgtccgg caggttggcg accagaccgc
    19981 gcagcgcctc gggaccgtcg gcggccagcg agctgtgctg ccggtagtcc ggcgccaccc
    20041 agcgatccac cgccgacggg tcgcggtcgc cgaacagctc accggcggcc ttgagcacga
    20101 gttccttgtt gttcatcacg tgtccgcttc tcacggtcgg cgggcccggc gcccgccgtc
    20161 gaccgcttca cgatctcccg cgggcggcgc cggcacgagg taggatcggg aaccgctatg
    20221 gtcagaagtg gacaggaccg acctctggtc gagttcggct tcagtaatcc ggaccggcca
    20281 cggctcggcg tcgagttggt ggactactcg ctgctgagca gtcgcttgcc gccggaaacg
    20341 ctggccgcgg tgcatcggac ggacttccac cagctgtttc tgttccgggc cggcgaggcc
    20401 tcgacgatgg tcgatttcgc cgacctgcac tgtccggccg gcacgctgct ctctgtctgc
    20461 cccggtcgcg tgctccgtct gccgcgggcc gtcaccgccg acgtggacgc ggtcgccgtg
    20521 ttgttcacgg tgtcgttccc gccccggctg gagcgggtgc ggacgctgct cagcccgttc
    20581 ggaccggtca cctggtccgt gccggccgag gagtggggcg gcatcgaccg ggcggtcagc
    20641 gagctccagg ttgagtacag cagggcggcg gcggagaact ccacggtctc cacggatctc
    20701 gtccggcagt tgctcggcgc tctgctgctg cgtgtcgcgc ggctgccggt ggccatcgac
    20761 cacgccgacg acggccaccg aagtgacgag accttccaaa gcttccgacg cgaactcgaa
    20821 aaggacttcg cgacgacgcg caacgcggcc gtctacgcgg gccggatcgg ctattcgttg
    20881 cgtagcctca accgcgcctg tcaggcggcg accggtcgtt cggccaaggc cctgatcgac
    20941 gcgcgggtcg ccttggaggc caagcgaatg ctcgcgcaca ccacgctctc ggcggcggct
    21001 gtcggtcacc gcctcgggtt cagcgaggcc accaacttca ccaagttctt cgtccgcgag
    21061 accggactga ctcccggcgc cttccgcgcc gacgagctct gactaggact ccagcagtcg
    21121 ctgtccttcg cgggcccact ccgccttggc ccgcgccacc gccgcgatgc catcgaacac
    21181 atgcgccttc agccgggcga tccggtcgtg ctcctcggga tccc
//
