LOCUS       NZ_CP073318            21065 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Kutzneria sp. CA-103260 chromosome, complete genome.
ACCESSION   NZ_CP073318
VERSION     NZ_CP073318.1
KEYWORDS    RefSeq.
SOURCE      Kutzneria sp. CA-103260
  ORGANISM  Kutzneria sp. CA-103260
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Kutzneria.
REFERENCE   1  (bases 1 to 11609901)
  AUTHORS   Jorgensen,T.S., Gren,T., Kontou,E.E., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Complete Genome Sequence of the Rare Actinobacterium Kutzneria sp.
            Strain CA-103260
  JOURNAL   Microbiol Resour Announc 10 (30), e0049921 (2021)
   PUBMED   34323613
REFERENCE   2  (bases 1 to 11609901)
  AUTHORS   Joergensen,T.S., Gren,T., Gonzalez,I., Roman-Hurtado,F.,
            Oves-Costales,D., Thomsen,E., Charusanti,P., Genilloud,O. and
            Weber,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2021) Novo Nordisk Foundation Center for
            Biosustainability, Technical University of Denmark, Kemitorvet,
            Building 220, Kongens Lyngby, Hovedstaden 2800, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-APR-2021
            Assembly Method :: Flye v. 2.8-b1674; unicycler_polish v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 87.0x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:18:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,392
            CDSs (total)                      :: 10,326
            Genes (coding)                    :: 10,257
            CDSs (with protein)               :: 10,257
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 9 of 69
            Pseudo Genes (incomplete)         :: 63 of 69
            Pseudo Genes (internal stop)      :: 2 of 69
            Pseudo Genes (multiple problems)  :: 5 of 69
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:59:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 807841
            Orig. end                         :: 828906
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP073318.1.
            Bacteria and source DNA available from Professor Tilmann Weber,
            Technical University of Denmark, Kemitorvet Building 220, room 327D
            2800 Kgs. Lyngby, Denmark.
            Annotated using prokka_raw 1.14.6 from
            https://github.com/tseemann/prokka.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21065
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="RiPP-like"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..21065
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..21065
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11065](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11065
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            17..883
                     /locus_tag="JJ691_RS03480"
                     /old_locus_tag="JJ691_06970"
     CDS             17..883
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015100866.1"
                     /locus_tag="JJ691_RS03480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_06970"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_211767349.1"
                     /transl_table=11
                     /translation="MTKAVTLLGTGLMGAGMARSLLRAGLAVTVWNRSADKARPLADDG
                     ATVAADPVSAVAGADVVVTMLFDAESVEEVMAEAIGSLKPGAVWVQSATVGLDGVEALA
                     ALAAKHNVPFLDAPVLGTRQPAEEGKLIVLAGGDPALRPSVDPVFEAIGARTLWVGPRI
                     GDGHRLKLAANSWVLSLTAGTAQALALTRNQGLDPQLFLDLIAGGGLDNPYAQLKGRAM
                     IADEFPASFSLDGAVKDAGLIAAALRAAGADDRLMTALHQQYGAAAEAGHGSSDMAAVF
                     KAHGEAQ"
     gene            880..1383
                     /locus_tag="JJ691_RS03485"
                     /old_locus_tag="JJ691_06980"
     CDS             880..1383
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009080283.1"
                     /locus_tag="JJ691_RS03485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_06980"
                     /product="DUF664 domain-containing protein"
                     /protein_id="WP_211767350.1"
                     /transl_table=11
                     /translation="MNIAELLTDGFDRVHGEVHEALGGLSADQLAWRVTPEANSIAWLV
                     WHLTRVQDDHVSEVAGVAQTWIEDGWVGRFALPFAEDATGYGHDSDDVAAVRAEGDLLA
                     GYFDAVYARTIAYVATLTDPDLDRVVDRRWNPAVTLGVRLVSVLDDDIQHAGQALFVRG
                     ILSE"
     gene            1468..2007
                     /locus_tag="JJ691_RS03490"
                     /old_locus_tag="JJ691_06990"
     CDS             1468..2007
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013989.4"
                     /locus_tag="JJ691_RS03490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_06990"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_211767351.1"
                     /transl_table=11
                     /translation="MARRIVATEYVSLDGFMDEPGAWSMPYFSDEAGAFKWQELQESEA
                     MLLGRHTYEGFAAAWPTMTDTGEFGERMNSMPKHVLSRTLTTLTWNSTLVDGLDGIRKL
                     VDGQGGDLLLAGSGQVFKLLAQHDLIDEYRFMIFPVILGDGQLPLFQPGPRRALKLVDT
                     LMLPHGVIVHSYQRAS"
     gene            complement(2082..2291)
                     /locus_tag="JJ691_RS03495"
                     /old_locus_tag="JJ691_07000"
     CDS             complement(2082..2291)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012795748.1"
                     /locus_tag="JJ691_RS03495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07000"
                     /product="hypothetical protein"
                     /protein_id="WP_211767352.1"
                     /transl_table=11
                     /translation="MECGNCTRGLDHCHGTLIVHTTEFTECTEPMCEDLDEVRHLAIVD
                     CSAVDGGCDCVSIMDEQIVHDNVA"
     misc_feature    complement(2255..2270)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.66"
                     /tool="antismash"
     misc_feature    complement(2726..2744)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.76"
                     /tool="antismash"
     gene            complement(2919..4064)
                     /locus_tag="JJ691_RS03500"
                     /old_locus_tag="JJ691_07010"
     CDS             complement(2919..4064)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014741.4"
                     /locus_tag="JJ691_RS03500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07010"
                     /product="DUF222 domain-containing protein"
                     /protein_id="WP_211767353.1"
                     /transl_table=11
                     /translation="MKEITRELESMEPSGVMMDLLLGVDVESLTDDQKLTLLILTRKAM
                     AALHYVELSLVHGIEDTAEIAMAVREPEQSVVRQKEYSDVLDRLPQCAELLRRGEIDPR
                     RLKTVDDRVVHLTDPELVAQVDEALAEVAPELTRTQLARRATKAVAEADPLGYDQRRLK
                     AREDRRVEFTPLPDGMAQLSIILPAIDARQAYDLLTQDARALAKDDRTTDQKRADAFLD
                     RFLGYGVDRKVQVHVTIPVETLMGLTEDPGLLDGYGPIAADSARELAMHGPWRGLLLDN
                     RRHADSMTTHKYRADAPTREFIKVRDGGTCTAPGCTTPIQELDHTVPWPVGKTTATQLK
                     GYCAHHHHLKHRDYTATLDPDGTLHWHTPQGRHYTTHPHQY"
     cand_cluster    2922..13722
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2922..13722
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[7921:8722](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(7922..8722)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     gene            complement(4344..5231)
                     /locus_tag="JJ691_RS03505"
                     /old_locus_tag="JJ691_07020"
     CDS             complement(4344..5231)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227088.1"
                     /locus_tag="JJ691_RS03505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07020"
                     /product="Ku protein"
                     /protein_id="WP_211767354.1"
                     /transl_table=11
                     /translation="MRAMWKGTVAFGLVAIPINLYAATENKGVTLRQVHEADGGRIQYK
                     RYCSVEDAEVPYAEIAKGYELDDGRMVVLTDAELSSLPLPTQKTIDVLEFVPLAAIDPL
                     FFDKAYYLEPQKSAVKPYVLLRDALHKSGHVAIAKVALRQREVLAVLRVHADVLTMSTM
                     LWPDEVRTPDFSFLQQDPPQVREQELTMAGQLIDSLAEPVFEPDRYQDSYRQALENLID
                     AKIEGDEVATPPGAEPTAEVVDLISALQASVKAAGKAKTPAPKARSTRKPAEKPVEKPA
                     EKKVPAKRRSSRSA"
     misc_feature    5322..5337
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.26"
                     /tool="antismash"
     gene            complement(5396..7336)
                     /locus_tag="JJ691_RS03510"
                     /old_locus_tag="JJ691_07030"
     CDS             complement(5396..7336)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013228262.1"
                     /locus_tag="JJ691_RS03510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07030"
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_211767355.1"
                     /transl_table=11
                     /translation="MTISRRTFLGSTAAVTALAALPLSTSQAGAASPAGDVVGKITVGY
                     QGWYACIGDGAPINTWWHWSQDASQTPSPTNNNNIKAWPDMREFSKGYQTAYSNLGNGQ
                     PATLFSQYDAQTVDTHFAWMSQYGCDTAALQRFNPNGSEGPTRDAVTAKVRTSAEAHGV
                     KFYIMYDATGWTNMQSEMKADWTAKMSAYTASPMYARQNGKPVVGIWGFGFNDNNHTWD
                     AATCLDVINWFKGQGCYVMGGVPREWRVGGAGTRTGFIDTYHAFNMISPWMVGAIGNIG
                     DSDNIYNTINVGDQADCNSHGIDYQPCVLPGDVSGRQRAHGDFMWHQFYNMVRVGAQGI
                     YISMFDEFTEGNQIAKSAESSATTPTNSGMLALDEDGTPCSSDYYLRLTGDGGRMLKGQ
                     IALTATRPTPPMVGGGDTQAPSVPSGLHATAHTATSATLAWTAATDNVGVTGYRIFANG
                     SQVGTTASTSFTANGLTPSTTYSFTVTAQDAAGNSSPASAAASVTTDAGGSTNLALNRP
                     TAESSHTQVYASGNAVDGNSGTYWESANNAFPQWLQVDLGASTPVSRIVLALPPLSAWG
                     ARTQTLTVAGSTDGSTFSTLVGSAGYTFDSNTGNTVTIPVPAGSRRYLRLTFTANTGWP
                     AGQVSEFQVYA"
     gene            7527..7925
                     /locus_tag="JJ691_RS03515"
                     /old_locus_tag="JJ691_07040"
     CDS             7527..7925
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.4"
                     /locus_tag="JJ691_RS03515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07040"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_249227656.1"
                     /transl_table=11
                     /translation="MIKTVALVHVRNSTVLLVRSHGRKAFYLPGGKYEPGETDLAALTR
                     EVAEEIGCRLRPETVRRHGVFEGDAHDQPPGTQVQINCYEGEFDGEPAACSEIEECGYY
                     TYAEYTAMAETAPVVHAIVDDLHRHKRI"
     gene            complement(7922..8722)
                     /locus_tag="JJ691_RS03520"
                     /old_locus_tag="JJ691_07050"
     CDS             complement(7922..8722)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020664856.1"
                     /locus_tag="JJ691_RS03520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07050"
                     /product="family 1 encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_211767357.1"
                     /sec_met_domain="Linocin_M18 (E-value: 9.5e-94, bitscore:
                     312.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLHRELAPISESAWADIEAEARRTFTRHVAGRRVVDLSGPAGE
                     TLSAVGTGHLSELESAAEGVRLRRREVQPIVEIRVPFTVSRAAVDDVERGAKDADWDPV
                     KEAAKRIAFVEDRAIFEGLSGAGIDGVRAATTNEALALPSDVREYPNVVAQALSALRLA
                     GVDGPYSLLLSADAYTAVEETTDHGYPIREHLSRVIHGGDIIWAPAIDGAFLLSARGGD
                     YELHLGQDLSIGYSSHDAQSIELYFQESLTFQVHTGEAGIALRV"
     gene            complement(8719..9729)
                     /locus_tag="JJ691_RS03525"
                     /old_locus_tag="JJ691_07060"
     CDS             complement(8719..9729)
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020664855.1"
                     /locus_tag="JJ691_RS03525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07060"
                     /product="Dyp-type peroxidase"
                     /protein_id="WP_211767358.1"
                     /transl_table=11
                     /translation="MASAEPQAVLTPLTEAAIFLVATVGDGGEEAVRDLLADVAGLTRS
                     VGFRIADGGLTCVVGVGSSAWDRIYPGVGRPAGLHPFTELVGDRHTAPSTPGDLLFHIR
                     AMRMDLCFELAEHLTTRLDGAITVVDEVHGFKYWDRRDLLGFVDGTENPTGGAAAAAVT
                     IGDEDPDFAGGSYVIVQKYLHDMTSWNRLSIEEQERVIGRTKLADLELADDVKPADSHV
                     ALNTVTDDNGEERQILRDNMPFGRVGSAEYGTYFIGYAADPGVIEQMLRNMFIGRPEGN
                     TDRVLDFSTAVTGTLFFVPTADFLEDPPESEQAQDEEPAERVTVSLRVGSLKGTP"
     gene            10001..11065
                     /locus_tag="JJ691_RS03530"
                     /old_locus_tag="JJ691_07070"
     CDS             10001..11065
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="JJ691_RS03530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07070"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_211767359.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.6e-46, bitscore:
                     157.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEARVNQVSTLDRFRTDLDRVRRRADRQLSALFDRAIAEESGPSR
                     YGLSELRGMALAGGKRIRPAFVHWAFVAGGGDPDDNRAIDAGSVLELLHVFALVHDDVM
                     DESPTRRGLPTLQVTFADRHRALGMRGCPERYGENMAILLGDFAFLLCTELAAMLPRPA
                     MRTFYRAATQLMHGQYLDLETTATGEFDGETAARTARLKTGSYTVEGPLLIGAALAPRG
                     REIQSALEVYGRAVGQAFQLCDDLLDVFGEEAETGKPVGGDITHHKATRLLDIARTRAV
                     GRDRELLNRLADQPVDLATMRSLLTRTGAVDELEYTIDALVTEAVEALYEAPMAASGRE
                     SLIDAAHFAGRRKA"
     misc_feature    10151..10153
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11110..12054)
                     /locus_tag="JJ691_RS03535"
                     /old_locus_tag="JJ691_07080"
     CDS             complement(11110..12054)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020644386.1"
                     /locus_tag="JJ691_RS03535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07080"
                     /product="PD40 domain-containing protein"
                     /protein_id="WP_211767360.1"
                     /transl_table=11
                     /translation="MKKIILAVAGTVLLVVAAVVYTVSARPHTADAVPAAQLTLAPGQL
                     LYRDVSTGRIAAAPLANPGAKPQVSGLKCDRFAVAARTAVCLAVRPGTLPALTDVIVLD
                     DHLNVRHTETLPGTPSRARVSPDGKLVYWTLFVTGDSYAATGFSTRAGIYEVATGTLVK
                     TVEELAVFVDGSRYTASDVNYWGLTFAPDGNRFYATLGSRGKTYLIEGDYAHYRGKALR
                     ENVECPSLSPDGSRVAFKKKISDGVWRLSVLDLATLRETELAETRSVDDQALWQDDHTV
                     LYGLDNAVWAVPADGSGPPRRLAAGASSPAVTG"
     gene            complement(12051..13286)
                     /locus_tag="JJ691_RS03540"
                     /old_locus_tag="JJ691_07090"
     CDS             complement(12051..13286)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104625.1"
                     /locus_tag="JJ691_RS03540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07090"
                     /product="MFS transporter"
                     /protein_id="WP_211767361.1"
                     /transl_table=11
                     /translation="MYIATSRASDLAAGTERKPALRRVAANVVALGLVSLVTDVSSEMV
                     TAVLPLYLVLGLGLNPLQFGLLDGLYAGATAVVRVLGGHLADRWRRLKAVAGFGYGLSA
                     VCKLGLIAAGSSVAAIGVVLAADRTGKGLRTAPRDALISLSSEPGTLGRSFGVHRALDT
                     VGAFLGPLVAMAVLALSFGDYSSVFFTSFCVAGIAVLLLALFVRDRPGSMDRAAVSLRA
                     AANLLRAKDFRRVTWWAALLGLVTVGDSFVYLVLQRQWDVAATYFPLLPLGTAGVYLLL
                     AVPLGRLADRIGRWPVFLGGHAALCLALVLLCGPQAGFWLAVLALGLHGVFYAATDGVL
                     MAAAGPLVPQDLRATGLAVVQTGQAVARMLSSVLFGLSWTLWDLKPAVLVAAAGLAAVA
                     LAAAFVRPVRTS"
     misc_feature    complement(12606..12608)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13299..14918)
                     /locus_tag="JJ691_RS03545"
                     /old_locus_tag="JJ691_07100"
     CDS             complement(13299..14918)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020661727.1"
                     /locus_tag="JJ691_RS03545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07100"
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_211767362.1"
                     /transl_table=11
                     /translation="MSSTRLRPLGRLAPVLAAVLLLPAAFVAAGASPSADVLLSQGKPV
                     ATSTVESSSYAGSKAVDGNTTGTRWASVAGADPQWLRVDLGQAATVHRVVINWEAAYAK
                     QYRIEVSDDGTNFTTVTAVDSGDGKTDDLTGLSGHGRYVRFVGLARATSYGYSFYEMQV
                     FGVADSAGDTQAPTTPTGLTAGQTSATSVALSWNAATDNVAVAGYDILRNGAVVASSED
                     PTYSDIALASDTTYTYAVRSRDTAGNVSPASAPITVRTKAGGSGAFVLAAAGDIAEQCT
                     ASDSNCVHVKTAKLVDQMRPAALITMGDNQYDDAHLSDYRNYYDKTWGKFRSITHPVPG
                     NHDTYDEPKYNGYDTYFGSVAKPNGQRYYSWDMGNWHFIALDSTAYMTHDDFAPDDSGA
                     DQIAWLKQDLAKNTKGCVAAYYHHPRWSSGDHGDNKDSVQLWNIMVDNKVDLVLNGHDH
                     DYERFVPQNASGKADAAGPVEIVGGSGGANLYDLSAKHPTTAKLLKTYGVLKLSMTDST
                     FQTQLIGVDGKTLDSSPTYTCH"
     misc_feature    complement(14853..14855)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14883..14885)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15094..15297
                     /locus_tag="JJ691_RS03550"
     CDS             15094..15297
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JJ691_RS03550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_211767363.1"
                     /transl_table=11
                     /translation="MLLAFVAALLVRGRTPAVAGVGALSWHPCEEDSIADCATLTLPVD
                     RADPATLPIRPPLGSARISHRD"
     gene            complement(15333..16763)
                     /locus_tag="JJ691_RS03555"
                     /old_locus_tag="JJ691_07110"
     CDS             complement(15333..16763)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082968.1"
                     /locus_tag="JJ691_RS03555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07110"
                     /product="carboxylesterase family protein"
                     /protein_id="WP_211767364.1"
                     /transl_table=11
                     /translation="MSLSHWEVALDSGAVRGRVSDDVAVFHAIPYAAAPQGPGRFAAPQ
                     PPARWPDVRDATVPGPTAPQPQRGAFGELDMSPYFGSGWVPGEEYLSVDVWTPAGRHAD
                     LPVMVFVHGGGFSAGSTRSPLYDGTAFARDGVVLVTVNYRLNVAGFLHLPDAPDNRGLL
                     DVLAALRWVSRNITAFGGDPTNVTVFGQSAGATLIAALLADPRVDGLVRRAILQSGSGT
                     GAFSRNQAKLVTRQLALRLGVPGTATALAAMSDADLVSACSALAGLDLTVDGTPDPLMG
                     LSPFSVVADEQPAAALARGRAEGVDLLLGTNSDEGRLYVISGATTWKDVHDTAAMMSPE
                     PAKTVAAHRQTRPDASAREIRAALLTEGLFGSGTRALARAHPPHNTYRYEFTWQSSELG
                     AAHVMELPFVFDLPHLPTLSGHGKLFGTAVPPPDLARRMHGAWVRFAMTGAPGWPAYGE
                     HGVGMRIGDTWQEATDSA"
     gene            complement(16763..17683)
                     /locus_tag="JJ691_RS03560"
                     /old_locus_tag="JJ691_07120"
     CDS             complement(16763..17683)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336594.1"
                     /locus_tag="JJ691_RS03560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07120"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_211767365.1"
                     /transl_table=11
                     /translation="MSPIDLGSVTLTRVPEFFGSVELTPETFFPDSTPSMWQDNESWLV
                     PHFLDNDAGMVRSAIQTWVLRSQGRTILIDTGVGNGKERPYVPLWGHRRSNFLADLAAA
                     GVRPEEVDIVVNTHLHNDHVGWNTVLAGREWVPTFPNARYLMPARDFEYWNPAGGHVPA
                     GGSHNQNVFEDSVAPVHRAGLVDLWEGEHVIDDGIRLAAAPGHTPGSSVVLVESAGTRA
                     MFVGDLVHSPLQFLHPDVNSCFCEDPEQARATRRDLLARAADEHSLVFPAHLGGGGGVR
                     VRAEGAGFALRDWAPFSAPERTGDE"
     gene            17838..18716
                     /locus_tag="JJ691_RS03565"
                     /old_locus_tag="JJ691_07130"
     CDS             17838..18716
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020495710.1"
                     /locus_tag="JJ691_RS03565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07130"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_211767366.1"
                     /transl_table=11
                     /translation="MSGTGRLAEYLQACRSRLRPEDVGLGTYGERRRVPGLRREEVAGL
                     AGVSTSYYVRLEQGQSLNASTEVIDGIARALRLDPDEHEHLRALARPPRQSAAPRPPAE
                     RVAPATAELMAALGDVPAVLLGRRNDVLAWNPLGHALFAGHLDPDSPSRPQERPNMARL
                     VFRDAHTRELYPQWTAKARAVVGNLRLVAGRHPEDRELNTLIGELVTSSPEFATMWADH
                     RVRTCSTAGHRMRHPLVGDLTVNQQPLLLAHAPEHTLTIVTAEPDSPSQAALDLLARAV
                     SEGRPRSAGNP"
     gene            complement(18727..19317)
                     /locus_tag="JJ691_RS03570"
                     /old_locus_tag="JJ691_07140"
     CDS             complement(18727..19317)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="JJ691_RS03570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07140"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_211767367.1"
                     /transl_table=11
                     /translation="MTLFAERGFDEVTIPQIADAAGVSKMTVTNYFPRKEDLVFDQAEA
                     TIRSLADAVAARARGESMLTAIRRDCTHRIAAGDVTLGPPGAVFARIVDDSRVLTHRAR
                     EIADLRERALGDAIAAETGEDSLRLRVIATQLASVHRALFTETSRRVLAGEPRDAVFAE
                     LATTAPRIFDLMEPSLGEFCRRRDLPPGPAEQA"
     gene            19478..20431
                     /locus_tag="JJ691_RS03575"
                     /old_locus_tag="JJ691_07150"
     CDS             19478..20431
                     /NRPS_PKS="Domain: PKS_ER (16-214). E-value: 9.9e-22.
                     Score: 69.4. Matches aSDomain:
                     nrpspksdomains_JJ691_RS03575_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012335.4"
                     /locus_tag="JJ691_RS03575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJ691_07150"
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_249227657.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.1e-10, bitscore:
                     38.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAVVHEWGHTPVLEDFETPEAGEGEVRVAVTASALTNFTKLRA
                     AGKHYSAATPPPFIPGIDGIGRSEDGRRVYFLFPRAPFGGLAEAAVVPSSRCVPVPDGV
                     DDITLAAIADPGMSSWAALEVRAKLTPGETVLINGATGTAGGLAVQIAKHLGASTVIVT
                     GRRRDALEPLLDHGADEIIELAEGEPLHAALRAAFQRGVDIVLDYLWGGSAESILAAAG
                     AGRADRPMRFIQIGTASARTITVPGDLLHSSAIEIMGSGVGSVHPTAIMGILGRLMNAA
                     PAAGFHVATRAFSLTEVGDAWSVEARTPRVVVTMNR"
     aSDomain        19526..20119
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JJ691_RS03575_PKS_ER.1"
                     /evalue="9.90E-22"
                     /label="JJ691_RS03575_PKS_ER.1"
                     /locus_tag="JJ691_RS03575"
                     /protein_end="214"
                     /protein_start="16"
                     /score="69.4"
                     /tool="antismash"
                     /translation="DFETPEAGEGEVRVAVTASALTNFTKLRAAGKHYSAATPPPFIPG
                     IDGIGRSEDGRRVYFLFPRAPFGGLAEAAVVPSSRCVPVPDGVDDITLAAIADPGMSSW
                     AALEVRAKLTPGETVLINGATGTAGGLAVQIAKHLGASTVIVTGRRRDALEPLLDHGAD
                     EIIELAEGEPLHAALRAAFQRGVDIVLDYLWGGSA"
     CDS_motif       19871..19933
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JJ691_RS03575_0001"
                     /evalue="3.10E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="JJ691_RS03575"
                     /protein_end="152"
                     /protein_start="131"
                     /score="16.6"
                     /tool="antismash"
                     /translation="GETVLINGATGTAGGLAVQIA"
ORIGIN
        1 ggaaggagtc ctggtcgtga ccaaggcagt gacgctgctc ggcaccgggc tgatgggggc
       61 cggcatggcc cgcagcctgc tccgggccgg cctggccgtg acggtgtgga accgcagcgc
      121 ggacaaggcc cggccgctgg ccgacgacgg cgcgaccgtc gcggccgacc cggtgtccgc
      181 cgtggccggc gccgacgtcg tcgtgaccat gctgttcgac gccgaatcgg tcgaagaggt
      241 gatggccgag gcgatcggat ccctcaagcc tggagcggtg tgggtgcaga gcgccaccgt
      301 cggccttgac ggcgtggaag ctctcgccgc gttggcagcc aagcacaatg tgccgttcct
      361 ggacgcgccg gtgctgggca cccggcagcc ggccgaggag ggcaagctga tcgtgctcgc
      421 cggcggcgac ccggcgctgc gcccgtcggt ggacccggtg ttcgaagcca tcggcgcccg
      481 caccctgtgg gtcgggccgc gcatcggcga cgggcaccgg ctcaagctgg ccgccaactc
      541 gtgggtgctg tccctgaccg ccggcaccgc gcaggccctg gccctgaccc gcaaccaggg
      601 gctcgacccg cagctgttcc tcgacctcat cgccggcggc gggctggaca acccgtacgc
      661 gcagctcaag ggccgggcca tgatcgccga cgagttcccg gcctcgttca gcctggacgg
      721 cgcggtcaag gacgccgggc tcatcgccgc cgcgctgcgg gccgccggcg ccgatgaccg
      781 gctgatgacc gccctgcacc agcagtacgg cgcagccgcc gaggccgggc acggctccag
      841 cgacatggcc gccgtcttca aggctcacgg ggaggcgcag tgaacatcgc cgagctgctc
      901 accgacggct tcgaccgggt gcacggcgag gtgcacgagg cgttgggcgg cttgagcgcc
      961 gaccagctgg cgtggcgggt cacccccgag gccaactcca tcgcctggct ggtgtggcac
     1021 ctcacgcgtg tgcaggacga ccatgtctcc gaggtcgccg gcgtggcgca gacgtggatc
     1081 gaggacggct gggtcggccg gttcgcgctg cccttcgccg aggacgccac cggctacggc
     1141 catgactccg acgacgtcgc cgccgtgcgg gccgagggcg acctgctcgc cggctacttc
     1201 gacgccgtct acgcacggac cattgcctac gtcgccacgc tgaccgaccc cgacctcgac
     1261 cgtgtcgtcg accgccgctg gaatccggcg gtgacgctcg gcgtgcggct ggtcagcgtg
     1321 ctcgacgacg acatccagca cgccggccag gccctgttcg ttcggggcat cctttcagag
     1381 tgaccggcgt cacatccccg gtgtgtcgag cggttcgcgg gccgctcgac gcgtaggcag
     1441 gaacacgccg aacgaggagg aaccgagatg gcccgcagga tcgtcgccac cgagtacgtg
     1501 agcctggacg gcttcatgga cgagcccggc gcctggtcga tgccgtactt ctccgacgag
     1561 gccggcgcgt tcaaatggca ggagctccag gagtccgagg cgatgctgct gggccggcac
     1621 acctacgagg gcttcgcggc ggcatggccg accatgaccg acaccggcga gttcggcgag
     1681 cgcatgaact cgatgcccaa gcacgtgctc tcccgcacgc tgaccacgct gacctggaac
     1741 tccacgctcg tcgacggcct cgacggcatc cgcaagctgg tcgacggcca gggcggcgac
     1801 ctgctgctgg ccggcagcgg tcaggtcttc aagctgctgg cccagcacga cctgatcgac
     1861 gagtaccgct tcatgatctt cccggtgatc ctgggcgacg gccagctccc gctgttccag
     1921 cccgggccgc gacgggccct caagctggtc gacaccctca tgctgccgca cggcgttatc
     1981 gtgcacagct accagcgcgc ttcgtgatcc ccagttcgga ggccggtccc cggtccggcc
     2041 tcgctgctgt tcgggtcgtc aggttttagg ccacgtcgtc tttaggccac gttgtcgtgg
     2101 acgatctgct cgtccatgat cgacacgcag tcgcagccgc cgtccaccgc gctgcagtcc
     2161 acgatcgcca agtggcggac ctcgtccagg tcctcgcaca tcggctcggt gcactccgtg
     2221 aactcggtgg tgtgcacgat cagcgtgccg tgacagtggt ccagaccccg agtgcagttc
     2281 ccgcactcca tcgttacatc ctccgtgcga ttgactctcc cggtgactct tgctaccacc
     2341 gcgaggccgg agagtctcgc acaaccgccc ggcgtgtcgt gccaggggga gggcgggtgg
     2401 cggcggggcg gagggtgtat gaggggcggg cgggacgtgt gggtgggtcg tttggttggc
     2461 ggcgggggat tgagcagtct tcgagtcgat gcgccggggt ggcgtgatta ttgttgggtg
     2521 gctctgggtg ggatttcttg gtttctccgg gtggattttg cgtggagcct ctgggcgatg
     2581 gcagtcgagg caaagaagcg ggcaggctgc gcctgcctcg atcgccgaca gcttatgcca
     2641 tcgcccccct ccacgcaaaa tccaccctcc gaggtttgga gtgggggttg cttgggcggt
     2701 cgcgcttttc agtgctggcg ctttggctgg atttggatcc acttcacctt ttaccggcct
     2761 ctgtcgcatc catttcccgc tcttcactcg ggctgccttc tcgccaccct cttgctggcc
     2821 ttcacttcaa acccggcctt ccggcctcac ccttcgttgg ccagttcttc tgctttttcg
     2881 ggtgcggttt cgctgtggag ttgtcaagga acgggtggtc agtattggtg ggggtgggtg
     2941 gtgtagtggc ggccttgtgg ggtgtgccag tggagggttc cgtcggggtc gagggtggcg
     3001 gtgtagtcgc ggtgtttgag gtggtgatgg tgggcgcagt agcccttgag ttgggtggcg
     3061 gtggttttgc cgaccggcca gggaacggtg tggtcgagtt cttggatggg ggtggtgcag
     3121 ccgggggcgg tgcacgtgcc gccgtcgcgg actttgatga actcgcgggt gggggcgtcg
     3181 gcccggtatt tgtgggtggt catggagtcg gcgtggcggc ggttgtccag gaggaggccg
     3241 cgccaggggc cgtgcatggc cagttcgcgg gcggagtcgg cggcgatggg cccgtagccg
     3301 tccagcaggc cggggtcctc ggtcaatccc atcaaggtct ccaccgggat ggtcacatgc
     3361 acctggacct tgcggtcgac gccgtagccc aggaaccggt cgaggaaggc gtcggctcgt
     3421 ttctggtcgg tggtgcggtc gtccttggcc agggctcggg catcctgagt caggaggtcg
     3481 taggcctggc gggcgtcgat ggcgggcagg atgatgctga gctgggccat gccgtcgggt
     3541 agcggggtga actcgacccg ccggtcctcg cgggccttca ggcggcgctg gtcgtagccg
     3601 agagggtcgg cctcagcgac tgctttggta gcgcggcgag ccagttgagt gcgggtcagc
     3661 tcaggggcta cttccgccag ggcctcatcc acctgggcga ccagctcggg gtcggtcagg
     3721 tgaaccactc gatcatccac ggtcttgagc cggcgggggt cgatctcccc acgcctcagt
     3781 agctccgcgc actggggtag ccggtctagg acgtcgctgt attctttctg acggactacc
     3841 gactgctccg gctcacgaac ggccatggcg atctcggcgg tgtcctcgat cccgtgtacg
     3901 aggctgagtt caacgtagtg gagagccgcc atggccttgc gggtcagaat gagcagggtg
     3961 agcttctggt catcggtaag gctctccacg tccacaccca ggagcaggtc catcatgacc
     4021 cctgagggtt ccatggactc cagctctcgg gtgatttcct tcatgcctcc agaatactcg
     4081 cacacatgat cgaactcgac tcactaatgg gtgaattcgg aaggcttaac cggcctaccc
     4141 caaggacgcc cgccccttac ctcggagggt ggattttgtg tggagggggg cgatggcata
     4201 agctgtcggc gatcgaggca ggcgcagcct gcccggttct ttgcctcgat gccatcgccc
     4261 agaggctcca cgcaaaatcc acccggagca acccagaaat ctacccccga acgccaagcc
     4321 gcccgccact cattaccccg aactcacgca ctccgactcg accgccgctt ggccggaacc
     4381 ttcttctccg ccggcttctc gaccggtttc tcggccggct tgcgcgtact gcgggccttg
     4441 ggggccggcg tcttcgcctt ccccgcagcc ttcacgctcg cctgcaacgc gctgatcaga
     4501 tccaccacct ccgccgtcgg ctcagccccc ggcggcgtgg cgacctcatc cccttcgatc
     4561 ttggcgtcga tcaggttttc cagggcctgg cggtagctgt cctggtaccg gtcgggctcg
     4621 aacaccggct cggccaggga gtcgatcaac tgcccggcca tggtcagctc ctgctcccgc
     4681 acctggggcg gatcctgttg caggaacgag aaatcgggag tccggacctc gtcgggccac
     4741 agcatcgtcg acatggtgag cacgtcggcg tgcacccgga gcacggccag cacttcccgc
     4801 tgccgcagtg cgaccttggc gatggcgacg tgcccggact tgtgcagggc gtcccgcagc
     4861 agcacgtagg gtttgacggc ggacttctgc ggttccaggt agtaggcctt gtcgaagaac
     4921 agcgggtcga tcgcggccag cggcacgaat tcgagcacgt cgatggtctt ctgggtgggc
     4981 agcggcaggc tggacagctc agcgtcggtg agcacgacca tgcgcccgtc gtcgagctcg
     5041 tagcccttgg cgatctcggc gtacggcact tcggcgtcct caacggagca gtaccgcttg
     5101 tactggatcc gtccgccgtc ggcctcgtgc acctgccgca gcgtgacgcc cttgttctcg
     5161 gtcgcggcgt acaggttgat cgggatggcg accagcccga aggccaccgt gcccttccac
     5221 atcgcccgca tggcgctcac ccctcccagg cccggtgacc tgcgtgtacc ccatggtgag
     5281 cgatctcaac ggccagcgcc acagtgaacg aggcggcccg ggcgaacggg tgtgcgaaac
     5341 gtgcggggcc acgcgggaac cgccgggatc aaacccggcg gttcccgcgg ggggctcagg
     5401 cgtagacctg gaactccgag acctggccgg cgggccagcc ggtgttggcg gtgaaggtca
     5461 gccgcaggta gcgccggctg cccgcgggca cggggatggt gacggtgttg ccggtgttgg
     5521 agtcgaaggt gtagccggcg gagccgacga gcgtgctgaa ggtgctgccg tcggtggagc
     5581 cggcgacggt gagggtctgg gtgcgagcgc cccaggcgga cagtggcggc agggcgagca
     5641 cgatgcggct caccggggtc gatgcgccga ggtcgacctg aagccattgc gggaacgcgt
     5701 tgttagcgct ttcccagtag gtcccggagt tgccgtcgac ggcgttgccg gaggcgtaga
     5761 cctgggtgtg gctggactcg gcggtgggcc ggttcagcgc caggttggtg cttccgccgg
     5821 cgtcggtggt gacggaggcg gcggccgagg cgggggagga gttgccggcg gcgtcctggg
     5881 cggtgacggt gaaactgtac gttgtggacg gtgtcaggcc gttggcggtg aaggacgttg
     5941 acgccgtggt gccgacctgg gagccgttgg cgaagatccg gtagccggtg acgccgacgt
     6001 tgtcggtggc ggcggtccag gccagggtgg ccgaggtggc ggtgtgcgcg gtggcgtgca
     6061 gtccactggg gacggacggg gcctgggtgt cgccgccgcc gaccatcggc ggggtcggac
     6121 gggttgccgt caaagcgatc tggcccttga gcatgcggcc gccgtcgccg gtgagccgca
     6181 ggtagtagtc ggacgagcac ggggtgccgt cctcgtccag ggcgagcatg ccggagttgg
     6241 tcggtgtggt cgcggagctc tcggccgact tggcgatctg gttgccctcg gtgaactcgt
     6301 cgaacatgga gatgtagatg ccctgcgcac cgacgcggac catgttgtag aactggtgcc
     6361 acatgaagtc gccgtgcgcc cgctgccgac cggacacgtc gccgggcagc acgcagggct
     6421 ggtagtcgat gccgtggcta ttgcagtcgg cttggtcgcc gacgttgatg gtgttgtaga
     6481 tgttgtcgga gtcgccgatg ttgccgatgg cgccgaccat ccacggcgag atcatgttga
     6541 acgcgtggta ggtgtcgatg aacccggtcc gggtgccggc cccgccgacc cgccattccc
     6601 ttggcacgcc gcccatcacg taacaaccct ggcccttgaa ccagttgatg acgtccaggc
     6661 aggtcgcggc gtcccaggtg tggttgttgt cgttgaagcc gaagccccag atgccgacca
     6721 ccggcttgcc gttctgccgc gcgtacatcg gcgacgccgt gtacgcggac atcttggcgg
     6781 tccagtcggc cttcatctcc gactgcatgt tcgtccagcc ggtggcgtcg tacatgatgt
     6841 agaacttcac gccgtgggcc tcggccgacg tgcgcacctt ggcggtcacc gcgtcgcggg
     6901 tcgggccctc gctgccgttg gggttgaagc gttgcagcgc cgcggtgtcg cagccgtact
     6961 ggctcatcca ggcgaagtgg gtgtccacgg tctgcgcgtc gtactgggag aacagggtgg
     7021 ccggctgacc gttgccgagg ttcgagtacg ccgtctggta gcccttgctg aactcgcgca
     7081 tgtccggcca ggccttgatg ttgttgttgt tcgtcggcga cggggtctga ctggcgtcct
     7141 ggctccagtg ccaccaggtg ttgatcggcg cgccgtcgcc gatgcaggcg taccagccct
     7201 ggtagccgac ggttatcttg ccgacgacat caccggccgg gctggccgcg ccggcctggc
     7261 tggtgctcag ggggagggcc gccagcgcgg tgaccgcggc ggtggagcct aggaacgtcc
     7321 tgcgggagat ggtcacgggt gttcctctcg tccgtcattg cacgagatgg gcagggacct
     7381 cgaactgtag gcagaacgac aggggagagc aagatatgca tagagatgcg caaactttca
     7441 acgatcatgc gtagattagt gttgtactac cggagctgga tcgcgcgggc gcggtactga
     7501 ttattcggcc cggtagcgtg ccaggcgtga tcaagaccgt ggcgttggtg cacgtcagga
     7561 actcgacggt gctgctggtc cgctcgcacg ggcgcaaggc gttctacctg cccggcggca
     7621 agtacgagcc gggggagacg gacctggccg cgctgacccg ggaagtggcc gaggagatcg
     7681 gctgccggct gcggccggag acggtgcgcc ggcacggcgt cttcgagggc gacgcccacg
     7741 accagccgcc gggcacgcag gtgcagatca actgctacga gggggagttc gacggcgagc
     7801 cggcggcctg ctcggagatc gaggagtgcg gctactacac gtacgccgag tacacggcga
     7861 tggccgagac ggcgccggtc gtccacgcca tcgtggacga cctgcaccgc cacaaaagga
     7921 tctaaacgcg caaggcgatg ccggcctcgc cggtgtgcac ctggaacgtc agcgactcct
     7981 ggaagtacag ctcgatgctc tgggcgtcgt gcgaggagta gccgatggac aggtcctgcc
     8041 cgaggtgcag ctcgtagtcg ccgccgcggg ccgacagcag gaacgcgccg tcgatggccg
     8101 gggcccagat gatgtcgccg ccgtggatga cccgcgacag gtgctcccgg atcgggtagc
     8161 cgtggtcggt ggtctcctcg acggcggtgt aggcgtcggc cgacagcagc aggctgtacg
     8221 gcccatcgac gccggccagc cgcagcgcgc tcagcgcctg cgcgacgacg ttcgggtact
     8281 cgcggacgtc cgagggcagc gccagcgcct cgttggtggt ggcggcccgc acgccgtcga
     8341 tgcccgcgcc ggacaggccc tcgaagatgg cccggtcctc gacgaaggcg atccgcttgg
     8401 ccgcctcctt caccggatcc cagtcggcgt ccttggcccc gcgctccacg tcgtccacgg
     8461 cggcccggct gaccgtgaac ggcacccgga tctccacgat cggctgcacc tcacggcggc
     8521 gcagccgcac gccctcggcc gccgactcca gctcactcag gtgaccggtg ccgaccgcgg
     8581 acagggtctc gccggccggc ccggacaggt cgaccacgcg gcggccggcc acgtgccggg
     8641 tgaacgtgcg gcgcgcctcg gcctcgatgt cggcccacgc cgactcggag atcggcgcga
     8701 gctcccggtg caggttgttc acggtgttcc tttcaggctg ccgacgcgga gcgagactgt
     8761 cacacgttca gcgggctcct cgtcctgtgc ttgctcggat tccggcgggt cctcgaggaa
     8821 atcggccgtg ggcacgaaga acagcgtgcc ggtgacggcg gtggagaagt ccagcacccg
     8881 gtcggtgttg ccctcgggcc ggccgatgaa catgttgcgc agcatctgct cgatcacgcc
     8941 gggatcggcg gcgtagccga tgaagtaggt gccgtactcg gcgctgccga cccgcccgaa
     9001 cggcatgttg tcccgcagga tctgccgttc ctcgccgttg tcgtcggtga cggtgttcag
     9061 cgcgacgtgg gagtcggccg gcttcacgtc gtcggccagt tccaggtcgg ccagcttggt
     9121 gcggccgatc acccgctcct gctcctcgat cgacagccgg ttccaggagg tcatgtcgtg
     9181 caggtacttc tgcacgatca cgtagctgcc gccggcgaag tccgggtcct cgtcgccgat
     9241 cgtcaccgcc gccgcggccg cgccgccggt cgggttctcg gtgccgtcga cgaagcccag
     9301 caggtcgcgc cggtcccagt acttgaagcc gtgcacctcg tcgaccacgg tgatcgcccc
     9361 gtcgagccgg gtggtcaggt gctcggccag ctcgaagcac aggtccatgc gcatggcccg
     9421 gatgtggaac agcaggtcgc cgggtgtgga cggcgcggtg tgccggtcgc cgacgagttc
     9481 ggtgaacggg tgcaggccgg cgggccgccc gacgcccggg tagatccggt cccaggccga
     9541 cgagccgacg cccaccacgc aggtgagccc gccgtcggcg atccggaaac ccaccgaccg
     9601 ggtgaggccg gcgacgtcgg cgagcaggtc gcggaccgcc tcctcgccgc cgtcgccgac
     9661 cgtggccacc aggaagatgg ccgcctcggt cagcggcgtc agcactgcct gcggctccgc
     9721 actcgccatg ctcgcgatct taggcacaga cccgacgccc gggcaccccg gcgagtcccg
     9781 ctctcgggca actgaatgtc gagttccgga agtcgacaca tggctgcctg agagcgggac
     9841 tcgcgggaac tatgcgttta cccagtctgg atggcgtatg agtgatcgcg ggtaggcaac
     9901 catgggcacg cacaagcact ggggtggctt gaccagatgt cacgaacgcg ggggcggtcg
     9961 tccccggatg tgcccgcgcc ggtgtagcca gtctctagtc gtggaggcaa gggtgaacca
    10021 ggtcagcacg ctcgaccgtt tccggaccga cctcgaccgc gtccgccgcc gggccgaccg
    10081 gcagttgtcc gcgctgttcg atcgcgccat cgccgaggaa tccggaccca gccggtacgg
    10141 gctgtccgag ttacgaggca tggccctggc cggcggcaaa cggatccgac cggccttcgt
    10201 gcactgggcc ttcgtcgccg gcggcgggga tcccgacgac aaccgcgcca tcgacgccgg
    10261 ctcggtgctg gagctgctgc acgtcttcgc gctcgtgcac gacgacgtga tggacgagtc
    10321 gccgacccgc cgcggcctgc cgacgctgca ggtcacgttt gccgaccggc accgcgccct
    10381 ggggatgcgc ggctgccccg agcgctacgg cgagaacatg gcgatcctgt tgggggactt
    10441 cgctttcctg ctgtgcacgg agctggccgc gatgctgccc cggccggcca tgcgcacctt
    10501 ctaccgggcc gccacccagc tgatgcacgg ccagtacctg gacctggaga cgaccgccac
    10561 cggcgagttc gacggcgaga ccgcggcccg caccgcgcgg ctgaagaccg gtagctacac
    10621 cgtggagggc ccgctgctga ttggcgccgc gctggccccg cggggccggg aaatccagtc
    10681 cgcgcttgag gtttacggcc gggcggtggg ccaggccttc cagctgtgtg acgacctgct
    10741 ggacgtgttc ggcgaggagg ccgagaccgg caagccggtg ggcggcgaca tcacgcacca
    10801 caaggcgacg cgcctgctgg acatcgcccg cacccgcgcc gtcggccgcg accgcgagct
    10861 gctgaaccgg ttggcggacc agccggtcga cctggccacg atgcgttcgc tgctgacccg
    10921 caccggggcc gtggacgagc tggagtacac catcgacgcc ctggtgaccg aggcggtcga
    10981 ggccctgtac gaggcgccga tggcggcatc cgggcgtgag tcgctgatcg acgccgcgca
    11041 tttcgcgggc cgccggaagg cctgatcagc cccggtggcc ctcggctggc gggccgaggg
    11101 ccaccggcct caccccgtca cggccggcga ggacgcgccg gcggccagcc gtcggggcgg
    11161 gccggagccg tccgccggga ccgcccacac cgcgttgtcc agtccataga ggacggtgtg
    11221 gtcgtcctgc cagagggctt ggtcgtccac gctgcgggtc tcggcgagct cggtctcgcg
    11281 cagcgtggcc aggtcgagga cggacagccg ccagacgccg tcgctgatct tcttcttgaa
    11341 cgccacccgc gagccgtccg gggacagcga cgggcattcg acgttctccc gcagggcttt
    11401 cccacggtag tgggcgtagt cgccctcgat cagataggtc ttgccccggc tgccgagggt
    11461 ggcgtagaac cggttgccgt ccggggcgaa ggtgaggccc cagtagttga cgtcggaggc
    11521 ggtgtaccgg ctgccgtcga cgaacaccgc cagttcctcg accgtcttga ccagggtgcc
    11581 ggtcgccacc tcgtatatcc cggcccgagt ggagaaaccc gttgccgcgt aggagtcccc
    11641 ggtgacgaac agcgtccagt agacgagctt gccgtccggg gacacgcggg cgcggctcgg
    11701 cgtgccgggc agggtctcgg tgtggcggac gttgaggtgg tcgtccagga cgatcacgtc
    11761 ggtcagcgcc gggagcgtgc ccggccgcac ggccaggcac accgcggtcc gcgccgccac
    11821 cgcgaaccga tcgcacttca ggccgctgac ctggggcttc gccccggggt tggccagcgg
    11881 ggcggcggcg atgcggccgg tggagacgtc gcggtacagg agttggccgg gggccagggt
    11941 gagctgcgcg gccggcaccg catccgcggt gtggggccgg gcgctgaccg tgtacacgac
    12001 ggccgcgacg accaggagca cggtgccggc gacggcaagg atgatcttct tcatgatgtg
    12061 cgcaccggcc tcacgaatgc ggcggcgagg gcaaccgcgg ccaggccggc cgcggcgacg
    12121 agcacagcgg gcttcaggtc ccacagcgtc caggaaagtc cgaacaggac ggacgagagc
    12181 atgcgcgcca ccgcctgccc ggtctggacc acggccagtc cggtggcccg caggtcttgc
    12241 ggcacaaggg gtccggccgc ggccatgagc acgccatcgg tggccgcgta gaacaccccg
    12301 tgcaggccta gggcgagcac ggcgagccag aagccggcct ggggaccaca caacagaacc
    12361 agcgccagac acagggcggc gtggccgccg aggaacaccg gccaccggcc gatccggtcg
    12421 gccagccggc cgagcggcac ggccagcagc aggtagaccc cggccgttcc caatggcagg
    12481 agcgggaagt acgtcgccgc cacgtcccac tgtcgctgca ggacgaggta gacgaacgag
    12541 tcgccgaccg tgaccaggcc cagcagcgcc gcccaccacg tgacgcgccg gaagtccttg
    12601 gcccgtaaca ggttggctgc cgcccgcagc gacaccgcgg cccggtccat cgagccgggg
    12661 cggtcgcgga cgaacagcgc cagcagcagc accgcgatcc cggcgacgca gaagctggtg
    12721 aagaacaccg agctgtagtc gccgaaactc agcgccagca ccgccatcgc caccagtggc
    12781 ccgaggaacg cgccaacggt gtccagggcg cggtgcaccc cgaacgaccg cccgagcgtc
    12841 ccgggctcac tgctgagcga gatcagcgca tccctcggcg cggtgcggag tcccttgccg
    12901 gtgcggtcgg cggcgagcac gacgccgatc gccgcgaccg aggagccggc cgcgatcagc
    12961 ccgagcttgc acaccgcgga caagccgtac ccgaacccgg cgaccgcctt gagccggcgc
    13021 caccggtcgg cgagatggcc gccgagcacc cgcacgaccg cggtcgcgcc ggcgtagagc
    13081 ccgtccagca acccgaactg caacgggttc aaacccaggc ccagcaccag gtagagcggg
    13141 aggacggcgg tgaccatctc cgacgacacg tcggtgacca gactgaccag cccgagcgcc
    13201 accacgttgg cggcgacccg ccgcagcgcc ggtttccgct ccgtcccggc cgccaggtcc
    13261 gaggcacggc ttgtcgcgat gtacatgccg gctcctccct agtggcaggt gtaggtcggg
    13321 ctgctgtcca gcgtcttgcc gtcgacgccg atcagctgcg tctggaacgt ggagtccgtc
    13381 atcgacagct tcaggacgcc gtaggtcttc agcagcttcg cggtggtcgg gtgcttggcg
    13441 ctgaggtcgt agaggttggc gccgccggag ccgccgacga tctcgaccgg gcctgccgcg
    13501 tcggccttgc cgctggcgtt ctgcgggacg aaccgctcgt agtcgtggtc gtggccgttg
    13561 agcaccaggt cgaccttgtt gtccaccatg atgttccaca gctggacgct gtccttgttg
    13621 tcgccgtggt cgccggagct ccacctcggg tggtggtagt aggcggccac acagcccttg
    13681 gtgttcttgg ccaggtcctg cttcagccag gcgatctggt cggctccgct gtcgtccggg
    13741 gcgaagtcgt cgtgcgtcat gtaggcggtg gagtccagcg cgatgaagtg ccagttgccc
    13801 atgtcccagc tgtagtagcg ctggccgttc ggcttggcga cggacccgaa gtacgtgtcg
    13861 tagccgttgt acttcggctc gtcgtaggtg tcgtggttgc cgggcacggg atgggtgatg
    13921 ctcctgaact tgccccacgt cttgtcgtag tagttccggt agtccgacag gtgcgcgtcg
    13981 tcgtactggt tgtcgcccat ggtgatcagc gccgccggcc tcatctggtc gaccagcttg
    14041 gccgtcttga cgtgcacgca gttcgagtcg ctggcggtgc actgctcggc gatgtcgccg
    14101 gccgcggcga ggacgaacgc cccgctgccg ccggccttgg tccgcaccgt gatcggcgcg
    14161 ctggccggcg acacgttgcc ggcggtgtcc cgggaccgca cggcgtaggt gtacgtcgtg
    14221 tcggacgcca gcgcgatgtc gctgtaggtc gggtcctcgc tgctggccac gaccgcgccg
    14281 ttgcgcagga tgtcgtagcc cgcgacggcg acgttgtcgg tggcggcgtt ccaggacagg
    14341 gcgacgctgg tggcgctggt ctggccggcg gtgaggccgg tcggcgtggt cggcgcctgg
    14401 gtgtcgccgg cggagtcggc gacgccgaag acctgcatct cgtagaagga gtagccgtag
    14461 ctggtggccc gggccaggcc gacgaagcgc acgtagcggc cgtggccgga cagaccggtg
    14521 aggtcgtcgg tcttgccgtc gccactgtcg acggcggtga cagtggtgaa gttggtgccg
    14581 tcgtcggaga cctcgatccg gtactgcttg gcgtaggcgg cttcccagtt gatcaccacg
    14641 cggtgcacgg tggcggcctg gcccaggtcg acgcgcagcc actgcgggtc ggcgcccgcg
    14701 acgctggccc agcgggtgcc ggtggtgttg ccgtcgacgg ccttcgagcc ggcgtacgag
    14761 gaactctcca cggtcgaggt ggcgaccggt tttccctggg agagcagcac atcggcggac
    14821 gggctggcgc cggccgcgac gaaggccgcg ggtaacagca acaccgcggc gaggacaggg
    14881 gctaaccggc cgagtggccg taggcgggtg gacgacacgt cgcgctcctt caggggcctt
    14941 ggcgggggcg ggcggcggac gacgcagatg aacttcgggt aaacggttaa gaaactttcc
    15001 taactagcag ctgactgtag gagcagtcac cgatgtctga caagacgtga ctttgacctt
    15061 gaatcggtca agacgggcaa tcgggtgaac ggagtgctgc tcgcctttgt cgcggcgctg
    15121 ctcgtgcggg gtcggacccc ggcggtcgcc ggggtgggag cgctttcctg gcatccctgc
    15181 gaagaagact ccattgcgga ctgtgcaacg ctcacccttc cggtcgaccg ggcggatccc
    15241 gccaccctgc cgatccgccc gccgctgggc agcgcgcgga tcagccatag ggattgagtc
    15301 tcggcggccc gacgtgggcc gccgagacta gatcaggcgg agtcggttgc ctcctgccag
    15361 gtgtcgccga ttcgcatccc gacgccgtgc tcgccgtacg ccggccagcc gggggcgccg
    15421 gtcatcgcga atcggaccca tgcgccgtgc atccgccggg cgaggtccgg gggcggcacg
    15481 gcggtgccga agagcttgcc gtggccggac aacgtgggca ggtgcgggag gtcgaacacg
    15541 aatggcagct ccatgacgtg tgcggccccg agctccgagg actgccaggt gaactcgtac
    15601 cggtaggtgt tgtgcggcgg gtgggcccgt gccagggccc gggtgcccga accgaacagt
    15661 ccctcggtca gcagggcggc ccggatctcc ctcgccgacg cgtccggccg cgtctgccgg
    15721 tgcgcggcga ccgtcttcgc cggctcggga gacatcatcg cggcggtgtc atgcacgtcc
    15781 ttccaagtgg tggcaccgga aatcacgtag agcctgccct cgtcgctgtt ggtgccgagc
    15841 aggagatcga ccccctcggc ccggccacgg gccaaggcgg ccgccggctg ctcgtcggcg
    15901 acaacgctga acgggctgag tcccatcagc gggtccggcg tgccgtcgac ggtcagatcg
    15961 agtccggcca gtgccgaaca ggccgacacc agatcggcgt ccgacatcgc ggcgagggcg
    16021 gtggcggtgc cgggcacgcc gagccgcagt gcgagttgtc gcgtgacgag cttcgcctgg
    16081 ttccggctga acgccccggt gccgctgccg ctttgcagga tcgcgcggcg aacgaggccg
    16141 tccacccgag gatcggccag cagtgcggcg atcagggtcg cccccgcgga ctggccgaac
    16201 accgtgacgt tcgtggggtc gccgccgaac gcggtgatgt tgcggctgac ccatcgcagc
    16261 gccgccagca cgtcgagcag gccgcgattg tcgggtgcgt cgggcaggtg caggaacccg
    16321 gccacgttca gccggtagtt gacggtgacc agcacgacgc cgtcccgggc gaaggcggtt
    16381 ccgtcgtaga gtgggctgcg cgtcgaaccg gcggaaaacc cgcccccgtg cacgaaaacc
    16441 atcacgggca ggtcagcgtg acggccggcc ggcgtccata catcgacgga caggtactcc
    16501 tcgcccggaa cccaacccga cccgaagtac ggcgacatgt cgagctcacc gaacgcgccg
    16561 cgttgtggtt gcggtgcggt gggtcccggc accgtggcat cccggacgtc tggccagcgt
    16621 gccggcggtt gcggtgccgc gaaccggccg ggcccctgag gtgcggcggc atacggaatc
    16681 gcgtggaaca cggcgacatc gtcggacaca cgcccgcgca ctgcgcccga gtcgagggcg
    16741 acttcccagt gggacaagga catcactcgt ccccggtccg ctccggcgct gagaacggtg
    16801 cccagtcccg caaggcgaac cccgcgcctt ccgcacgcac gcgtaccccg ccgccaccgc
    16861 cgaggtgcgc gggaaagacc agtgaatgct cgtcggccgc acgggccagc agatcccggc
    16921 gcgtcgcccg cgcctgctcg gggtcttcgc agaagcagct gttcacgtcc gggtggagga
    16981 actgcagcgg gctgtgcacc agatcaccca cgaacatggc ccgggttccc gccgactcga
    17041 ccaggacgac cgacgagccc ggcgtgtgcc cgggcgccgc ggccaaccga atgccgtcat
    17101 cgatcacgtg ctcgccctcc cacaggtcga ccaacccggc ccggtgcacc ggtgcgacgc
    17161 tgtcctcgaa gacgttctgg ttgtgcgagc cgccggccgg gacgtgcccg ccggccgggt
    17221 tccagtactc gaagtcccgc gccggcatga gatagcgggc gttggggaag gtcggtaccc
    17281 actcccgccc cgccagcacg gtgttccacc cgacgtggtc gttgtgcagg tgggtgttga
    17341 cgacgatgtc cacctcctcc gggcgcaccc cggccgcggc caggtcggcg aggaagttcg
    17401 agcggcggtg cccccacaac gggacgtacg gccgctcctt gccgttgccg accccggtgt
    17461 cgatgagaat cgtccggccc tggctgcgca gcacccacgt ctggatcgcg gaccgcacca
    17521 tgcccgcgtc gttgtcgagg aagtgcggca cgagccagct ttcgttgtcc tgccacatcg
    17581 acggggtgct gtcggggaag aacgtctcgg gcgtgagctc cacggagccg aagaactccg
    17641 ggacacgggt gagggtgacg gagccaagat cgatcggtga catgggcgag ttctgcttct
    17701 ttctgaacgg tgggaaaagc ccgcggcagc ggactcgtcc accctcgtcc cggatgctcg
    17761 ggcccagcca gaccagcgtt gtcctaccac cggcatggtc aggctcggcc tcggccacgc
    17821 gtcgcatact ggacgtcatg agcggaacgg gtcggctggc cgagtaccta caggcatgcc
    17881 ggtcgcgtct gcggccggag gacgtcggcc tcggcaccta cggcgagcgg cgccgggtgc
    17941 ccggactgcg ccgcgaggag gtcgcgggcc tcgccggggt cagcacgtcg tactacgtcc
    18001 ggctggagca gggccagtcg ttgaacgcct cgaccgaggt catcgacggc attgcccggg
    18061 cactgcggct cgaccccgac gagcacgagc acctgcgcgc cctggcccgg ccgccgcgac
    18121 aatcggccgc gccacggccg ccggccgaac gggtcgcgcc cgccacggcg gaactgatgg
    18181 ccgccctggg cgacgtgccg gcggtcctgc tggggcggcg caacgacgtg ctcgcctgga
    18241 atccgctcgg ccatgccctg ttcgccggac atctcgaccc cgactctccc tcgcgcccgc
    18301 aggaacgtcc gaacatggcc cggctggtct tccgcgacgc gcacacccgc gagctctatc
    18361 cacaatggac agccaaggcc cgcgcggtgg tcggcaacct ccggctggtc gccggccgtc
    18421 acccggagga ccgtgaactc aacacgctca tcggcgaact ggtcaccagc agccccgagt
    18481 tcgcgaccat gtgggcggat caccgggtgc gcacgtgcag caccgccggg caccggatgc
    18541 gtcatccgct ggtcggagac ctcacggtga accagcagcc gctcctgctc gcccacgccc
    18601 cggagcacac gttgacgatc gtcaccgcgg agccggactc accatcacag gcggcactcg
    18661 acctgctcgc gcgggcagtg tcggagggac ggccccgcag tgcgggaaac ccctgacgct
    18721 agcgggtcat gcctgttccg ctggacctgg cggcaggtca cgtctgcggc agaactcgcc
    18781 cagtgacggc tccatgagat cgaagattcg tggggcggtc gtggccagtt cggcgaagac
    18841 cgcgtcgcgt ggttcaccgg ccagcacgcg cctgctggtt tcggtgaaca acgcgcgatg
    18901 caccgacgcg agctgagtgg cgatgacccg cagccggaga ctgtcttcgc cggtctcggc
    18961 cgcgatggca tcgcccaggg cgcgctctcg caggtcggcg atctcgcggg cgcgatgggt
    19021 cagtacccgg ctgtcgtcga cgatccgggc gaagacggcg ccgggcgggc cgagcgtgac
    19081 atcgcccgcg gcgatccggt gcgtgcagtc acggcggatc gcggtcagca tgctctcccc
    19141 gcgagcacgc gcggcgacgg cgtcggcgag gctgcggatg gtcgcctcgg cctggtcgaa
    19201 gaccaggtcc tccttgcgtg ggaagtagtt cgtcacggtc atcttcgaca ccccggccgc
    19261 gtcggcgatc tgcgggatcg tgacctcgtc gaagcctcgc tccgcgaaca gggtcatcgc
    19321 ggccgtggac agggtgtccc gggttcgctg cttgcgctgg tgacgtagcc cactcgccat
    19381 gggcacatcc tactgctgat cttgatccga cataaactta tgctagacat aagtttaggc
    19441 gcctcgtcgg ggtgccgcga acaggaaggc catcgagatg aaggcagccg tggtccacga
    19501 gtgggggcac actccagtcc tggaggactt cgagacccct gaagcaggcg aaggcgaggt
    19561 ccgggtcgcg gtgacggcct cggcactgac caacttcacc aagctgcgcg cggccggaaa
    19621 gcactacagc gccgccaccc cgcccccgtt catcccgggg atcgacggca tcgggcgaag
    19681 cgaggacgga cgccgtgtct acttcctgtt cccccgcgca ccgtttggcg gcctggccga
    19741 ggctgcggtc gtcccatcgt cccggtgtgt cccggtcccc gacggggtcg atgacatcac
    19801 gctggcggcg atcgcggacc ccgggatgtc gtcgtgggct gcactggagg tgcgcgcgaa
    19861 actgacaccc ggtgaaaccg tcctgatcaa cggcgccacc gggacggccg gcgggctcgc
    19921 ggtgcagatc gccaagcacc tgggagccag cacggtcatc gtcaccggcc gacgccgcga
    19981 cgcgttggag cccctgctcg accacggtgc cgacgagatc atcgaactgg ccgagggtga
    20041 accgctgcac gcggccttgc gcgccgcctt tcaacgcggc gtggacatcg tgctcgacta
    20101 cctgtggggc ggcagcgccg aaagcatcct cgccgcggca ggcgccggtc gcgccgatcg
    20161 cccgatgcgg ttcatccaga tcggaactgc cagcgcgcgc accatcaccg tgcccggtga
    20221 cctgctgcat tcctccgcca tcgagatcat gggaagcggc gtcggcagcg tccaccccac
    20281 cgcgatcatg ggcattctgg gcaggctgat gaacgcggcg ccggctgccg gttttcacgt
    20341 cgccacacga gctttttcgc tcaccgaggt tggggacgcc tggtcggtcg aggcccgcac
    20401 gccacgcgtc gtggtgacga tgaaccggtg atcggtcctg cacctgaccg aaaacggtgg
    20461 gattgcccac ccgatggcca caccttggcc ggcaccggtt ccgtgaccgg ttccagacaa
    20521 gtcgccccga ccctcttgtc tggcgcgtga ccacgtcgta ccactggttt gacgtggtcg
    20581 cggcaggcaa gggggcctca tgcggaaact gcgaagagtg ttggcggtcg gcgctgtgct
    20641 cgtgctcggc acggccgtcc cgggcgcggc ggcggccgcg ccggcgaatg gtccgaaccc
    20701 ggcgtgcccc tgggtgggct cgcacgcgcc gatcggcgcc aaggtggcgc aggtgctcgg
    20761 acagatgacc ctcgacgaga agatcgccat ggtgcacggg gcggccggct ccgcctacgt
    20821 cggctacgtg cccggcgacg cccggctgtg cattcccgcg ctgaagatgc aggacgggcc
    20881 ggtcggcgtc cgaatgcccg acaccaccca gctgcccgcc gccagcgacc tcgcggcgac
    20941 cttcgacccc tcgctggcgc acagctacgg caaggtgatc gggtcggagg acaaggccaa
    21001 gggcgtcgac gtcgacctcg ggccgaccgt gaacatcgtc cgcgacccgc gctggggccg
    21061 ggctt
//
