LOCUS       NZ_CP076083            22954 bp    DNA     circular CON 05-JUL-2024
DEFINITION  Bacillus subtilis strain SC3.7 chromosome.
ACCESSION   NZ_CP076083
VERSION     NZ_CP076083.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4026536)
  AUTHORS   Epparti,P., Gnanesh Kumar,B.S., Halami,P.M. and Sattur,A.P.
  TITLE     Whole Genome Sequencing of Bacillus subtilis from Soybean seed
            chutney
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4026536)
  AUTHORS   Epparti,P., Kumar,G., Halami,P.M. and Sattur,A.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2021) Microbiology and Fermentation Technology
            Department, Csir-Cftri, Valmiki Road, Mysore, Karnataka 570020,
            India
REFERENCE   3  (bases 1 to 4026536)
  AUTHORS   Epparti,P., Gnanesh Kumar,B.S., Halami,P.M. and Sattur,A.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2021) Microbiology and Fermentation Technology
            Department, Csir-Cftri, Valmiki Road, Mysore, Karnataka 570020,
            India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: NZ_CP020102.1
            Genome Coverage                   :: 845.83x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018224865.2-RS_2024_07_05
            Annotation Date                   :: 07/05/2024 03:05:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,155
            CDSs (total)                      :: 4,105
            Genes (coding)                    :: 3,996
            CDSs (with protein)               :: 3,996
            Genes (RNA)                       :: 50
            tRNAs                             :: 45
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 68 of 109
            Pseudo Genes (incomplete)         :: 55 of 109
            Pseudo Genes (internal stop)      :: 22 of 109
            Pseudo Genes (multiple problems)  :: 32 of 109
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:51:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 157800
            Orig. end                         :: 180754
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076083.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Microbiology and
            Fermentation Technology Department, CSIR-CFTRI, Bangalore.
FEATURES             Location/Qualifiers
     region          1..22954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..22954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..22954
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12954](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12954
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     protocluster    235..21467
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10234:11467](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10235..11467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     gene            421..960
                     /gene="adaB"
                     /locus_tag="KFF76_RS00930"
                     /old_locus_tag="KFF76_00930"
     CDS             421..960
                     /codon_start=1
                     /gene="adaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388063.1"
                     /locus_tag="KFF76_RS00930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00930"
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="WP_017694950.1"
                     /transl_table=11
                     /translation="METNKPTLYWSLLMFKEWNFYIASTLKGLVFVGSQNKPIEELFEW
                     ARKRFPGSLLVEDDDKLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQLAVWNALCEIPY
                     GQTKSYSDIANEINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEMKTL
                     LLDLEKRASSEMDVPH"
     gene            1479..2996
                     /gene="mpsA"
                     /locus_tag="KFF76_RS00935"
                     /old_locus_tag="KFF76_00935"
     CDS             1479..2996
                     /EC_number="1.6.5.9"
                     /codon_start=1
                     /gene="mpsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388064.1"
                     /locus_tag="KFF76_RS00935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00935"
                     /product="NADH dehydrogenase subunit 5"
                     /protein_id="WP_212130883.1"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFTLFTFTTGAASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKVSGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVINESLAGLGEWERTGIQLLIVLAVIIPAAQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVG
                     RHEVSARTNERTSYLWVMAGRILSLVIGVAFWLAAPGEGYQFISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGGAALVYFIIHNLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     gene            3011..5626
                     /gene="mpsB"
                     /locus_tag="KFF76_RS00940"
                     /old_locus_tag="KFF76_00940"
     CDS             3011..5626
                     /codon_start=1
                     /gene="mpsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388065.2"
                     /locus_tag="KFF76_RS00940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00940"
                     /product="YbcC family protein"
                     /protein_id="WP_212130881.1"
                     /transl_table=11
                     /translation="MGITSVLTKDNVKKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDVDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHELEKLVGECSGLDHIENVFMQPLSSY
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERVKGWPKEAHLALQEALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLTNERSKKTISIAPLIAAWIHWGGLTLEEWSQMTAIE
                     QNEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGGKKSALAQLAFCIDV
                     RSEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNKIKEFADED
                     VFKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIR
                     NLREAWLRKPDTKLSLHHDTTEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICG
                     HGSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLTEGIKIPEDTVFAA
                     AEHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQLPNFQSKLKNPK
                     AEANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLA
                     NIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQS
                     VMESDHEAYHSPLRLLILIQAPREYVERLLNHDSAFLQKVQNGWVRLASLDPEGCWESW
                     "
     gene            5703..6230
                     /gene="ybcF"
                     /locus_tag="KFF76_RS00945"
                     /old_locus_tag="KFF76_00945"
     CDS             5703..6230
                     /codon_start=1
                     /gene="ybcF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388067.1"
                     /locus_tag="KFF76_RS00945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00945"
                     /product="carbonic anhydrase"
                     /protein_id="WP_130573427.1"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGAGIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNELTQLETMKDKIQTLDYLFQNCK
                     PEFLGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSHVKVRGLLVNHKDGKPSIMEGPDA
                     KTGQAIPDHCLS"
     gene            6291..6581
                     /gene="ybcH"
                     /locus_tag="KFF76_RS00950"
                     /old_locus_tag="KFF76_00950"
     CDS             6291..6581
                     /codon_start=1
                     /gene="ybcH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388068.1"
                     /locus_tag="KFF76_RS00950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00950"
                     /product="DUF6407 family protein"
                     /protein_id="WP_015252954.1"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECMKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     gene            6639..7013
                     /gene="ybcI"
                     /locus_tag="KFF76_RS00955"
                     /old_locus_tag="KFF76_00955"
     CDS             6639..7013
                     /codon_start=1
                     /gene="ybcI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388069.1"
                     /locus_tag="KFF76_RS00955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00955"
                     /product="DUF2294 domain-containing protein"
                     /protein_id="WP_003246482.1"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNLEKIL"
     gene            7485..7787
                     /gene="ybzH"
                     /locus_tag="KFF76_RS00960"
                     /old_locus_tag="KFF76_00960"
     CDS             7485..7787
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="ybzH"
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097670.1"
                     /locus_tag="KFF76_RS00960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00960"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_003234907.1"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     gene            7914..9086
                     /gene="ybcL"
                     /locus_tag="KFF76_RS00965"
                     /old_locus_tag="KFF76_00965"
     CDS             7914..9086
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ybcL"
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388070.1"
                     /locus_tag="KFF76_RS00965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00965"
                     /product="MFS transporter"
                     /protein_id="WP_212130880.1"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVSFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLASITWVGALGVMIAIITSLTIFHSQPKQTLKDINQ"
     gene            <9187..9529
                     /locus_tag="KFF76_RS20605"
                     /pseudo=""
     CDS             <9187..9529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223659.1"
                     /locus_tag="KFF76_RS20605"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="glutamine--fructose-6-phosphate aminotransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VCVEGALKLKGIS"
     gene            10001..10168
                     /gene="skfA"
                     /locus_tag="KFF76_RS00970"
                     /old_locus_tag="KFF76_00970"
     CDS             10001..10168
                     /codon_start=1
                     /gene="skfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388072.1"
                     /locus_tag="KFF76_RS00970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00970"
                     /product="sporulation killing factor"
                     /protein_id="WP_009966416.1"
                     /sec_met_domain="TIGR04404 (E-value: 4.4e-37, bitscore:
                     123.7, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     aSDomain        10235..10537
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KFF76_RS00975_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="1.70E-16"
                     /identifier="RREFam021.1"
                     /label="KFF76_RS00975"
                     /locus_tag="KFF76_RS00975"
                     /protein_end="101"
                     /protein_start="0"
                     /score="51.4"
                     /tool="antismash"
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSL"
     gene            10235..11467
                     /gene="skfB"
                     /locus_tag="KFF76_RS00975"
                     /old_locus_tag="KFF76_00975"
     CDS             10235..11467
                     /codon_start=1
                     /gene="skfB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388073.2"
                     /locus_tag="KFF76_RS00975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00975"
                     /product="sporulation killing factor system radical SAM
                     maturase"
                     /protein_id="WP_003234902.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.5e-14, bitscore: 51.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 7.5e-31, bitscore:
                     105.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-21, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.8e-06, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4.9e-05, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLP
                     FQKEVKAGIQE"
     gene            11464..12954
                     /gene="skfC"
                     /locus_tag="KFF76_RS00980"
                     /old_locus_tag="KFF76_00980"
     CDS             11464..12954
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene="skfC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097671.1"
                     /locus_tag="KFF76_RS00980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00980"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_212130878.1"
                     /sec_met_domain="skfc (E-value: 4.1e-287, bitscore: 950.9,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 1.1e-12, bitscore: 46.1,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQF
                     IKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQ
                     SFVVGVNANREITFFYADVPKKTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIIFQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKKHYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     gene            12973..13695
                     /gene="skfE"
                     /locus_tag="KFF76_RS00985"
                     /old_locus_tag="KFF76_00985"
     CDS             12973..13695
                     /codon_start=1
                     /gene="skfE"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388077.1"
                     /locus_tag="KFF76_RS00985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00985"
                     /product="sporulation killing factor ABC transporter
                     ATP-binding protein SkfE"
                     /protein_id="WP_017694958.1"
                     /transl_table=11
                     /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIEGSPPGHINVQKKVALIPDQPYLYPALTAAEHIQFRARGYHP
                     GKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVLETADRVILIRDGKLMQDLYVPQFEEE
                     QAEWRKEVIRLLGEWSDE"
     gene            13688..15103
                     /gene="skfF"
                     /locus_tag="KFF76_RS00990"
                     /old_locus_tag="KFF76_00990"
     CDS             13688..15103
                     /codon_start=1
                     /gene="skfF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019257319.1"
                     /locus_tag="KFF76_RS00990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00990"
                     /product="sporulation killing factor system integral
                     membrane protein"
                     /protein_id="WP_212130876.1"
                     /transl_table=11
                     /translation="MNNIISFLWLQSKRRFVSQGQEKKMPFLIMLLFVGAIGFQVSFVS
                     RSTTWDMSIAGWVLTGVFILYTAFGLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFS
                     VTWKALLWIISAIFGDVLIVLLSGDHINLLGRSIIFVGLFFIAEVWLMSVSCARTVKKM
                     KRVYVLVFLLMLGIYSICLYQFFFLQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIG
                     IITVSFMTIAFTSRQVEMKESLVKEAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGI
                     WSFLWLELLLFKKYLFFHSIHTVMLSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSG
                     IVRHSQSGTLHLFPGALWKKIIILELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIY
                     IWFMTIRLFAFTHTNRNDIKLSLPQYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVC
                     IGSLSWCLFYRFR"
     gene            15150..15665
                     /gene="skfG"
                     /locus_tag="KFF76_RS00995"
                     /old_locus_tag="KFF76_00995"
     CDS             15150..15665
                     /codon_start=1
                     /gene="skfG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388079.2"
                     /locus_tag="KFF76_RS00995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_00995"
                     /product="sporulation killing factor biosynthesis/export
                     protein SkfG"
                     /protein_id="WP_003234897.1"
                     /transl_table=11
                     /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEAL
                     KEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVI
                     KIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGKLIA
                     FQLKDKED"
     gene            15670..16095
                     /gene="skfH"
                     /locus_tag="KFF76_RS01000"
                     /old_locus_tag="KFF76_01000"
     CDS             15670..16095
                     /codon_start=1
                     /gene="skfH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388080.2"
                     /locus_tag="KFF76_RS01000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_01000"
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_212130874.1"
                     /transl_table=11
                     /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPNCH
                     QLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIPIVLDQNYEIVTTC
                     HVQGIPSFCLLSKYGQIITKTMGDVGWDKMLKKIAGL"
     misc_feature    15688..15703
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.76"
                     /tool="antismash"
     gene            16344..17321
                     /gene="ybdG"
                     /locus_tag="KFF76_RS01005"
                     /old_locus_tag="KFF76_01005"
     CDS             16344..17321
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ybdG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388081.2"
                     /locus_tag="KFF76_RS01005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_01005"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_212130872.1"
                     /sec_met_domain="PF00561 (E-value: 5.2e-07, bitscore: 27.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVSVSVFIYHHFQLNKEAALLKGKG
                     TVVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKESKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     gene            17323..17994
                     /gene="ybdJ"
                     /locus_tag="KFF76_RS01010"
                     /old_locus_tag="KFF76_01010"
     CDS             17323..17994
                     /codon_start=1
                     /gene="ybdJ"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388082.1"
                     /locus_tag="KFF76_RS01010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_01010"
                     /product="response regulator transcription factor"
                     /protein_id="WP_212130870.1"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGDLLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKELGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRIRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     gene            17991..18977
                     /gene="ybdK"
                     /locus_tag="KFF76_RS01015"
                     /old_locus_tag="KFF76_01015"
     CDS             17991..18977
                     /codon_start=1
                     /gene="ybdK"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234894.1"
                     /locus_tag="KFF76_RS01015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_01015"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_212130868.1"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKTMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKPADQDVIWMSNALWLQRLFDNIFQNTLRHSKAKKMEVTIEHGDVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDNGTGFLFSKE"
     gene            19036..19299
                     /locus_tag="KFF76_RS01020"
                     /old_locus_tag="KFF76_01020"
     CDS             19036..19299
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097672.1"
                     /locus_tag="KFF76_RS01020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_01020"
                     /product="hypothetical protein"
                     /protein_id="WP_024571603.1"
                     /transl_table=11
                     /translation="MNSICLKKSSKRLSTSQAVLVTDIADTGITAAVGADIIAATAAVR
                     AKEDTTTVMAAVIVTNAGATAAVNPKKVLVPLLGQGFFYVTD"
     gene            complement(19284..20054)
                     /gene="pkrD"
                     /locus_tag="KFF76_RS01025"
                     /old_locus_tag="KFF76_01025"
     CDS             complement(19284..20054)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pkrD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388085.1"
                     /locus_tag="KFF76_RS01025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_01025"
                     /product="protein kinase"
                     /protein_id="WP_017694962.1"
                     /sec_met_domain="Pkinase (E-value: 4.5e-32, bitscore:
                     109.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLNSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIEEEYQHTASIREDLNRAIQSVT"
     gene            complement(20140..20997)
                     /locus_tag="KFF76_RS01030"
                     /old_locus_tag="KFF76_01030"
     CDS             complement(20140..20997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388086.1"
                     /locus_tag="KFF76_RS01030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_01030"
                     /product="hypothetical protein"
                     /protein_id="WP_121572518.1"
                     /transl_table=11
                     /translation="MVKKWLIPFAVMLSVLFTFTYSASAVGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYSNADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     VAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     misc_feature    21054..21063
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            21129..22313
                     /gene="ybdO"
                     /locus_tag="KFF76_RS01035"
                     /old_locus_tag="KFF76_01035"
     CDS             21129..22313
                     /codon_start=1
                     /gene="ybdO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009330280.1"
                     /locus_tag="KFF76_RS01035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KFF76_01035"
                     /product="DUF4885 domain-containing protein"
                     /protein_id="WP_212130866.1"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTSVSGNSGTFSKVYQSANDRTVTDTGEETVIQCQNPYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAAFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGTDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSAQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPEGRDLMDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVND"
     misc_feature    22374..22388
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.38"
                     /tool="antismash"
     misc_feature    22394..22407
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.64"
                     /tool="antismash"
     misc_feature    22853..22867
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
ORIGIN
        1 tatgtatttt tccaaacgca gaacaagctc tccgcgcaaa ttttcgccct tgtaaacgtt
       61 gcaagcccac taatgaaaaa atgcctgata gcgagtgggt tgatctaatt actgaataca
      121 ttgataaaaa tttcacagaa aaattaacgc tagaatcgtt agcagatatt tgtcatggga
      181 gtccgtatca tatgcatcga acatttaaaa agattaaagg cattacgctg gttgagtata
      241 tacaacaagt tagagtacac gcggctaaaa agtatttgat tcagacaaat aaatcgattg
      301 gagatatcgc tatatgtgtg ggtatagcta acgcgcctta ttttattact ttatttaaaa
      361 agaaaactgg acagacacca gcacaatttc gtcaaatgag taaaatggag gaaacgtaca
      421 atggaaacaa ataaaccaac cctttattgg tctttactaa tgttcaagga gtggaatttt
      481 tatattgctt caactttaaa ggggcttgtg tttgtaggtt cacagaacaa accaatcgag
      541 gaattgttcg aatgggctag gaaacgcttt ccgggaagtc ttcttgttga agatgatgat
      601 aagcttgaac cctatgccgt tgaaatcact caatatctag aaggaaagcg gaaaaacttt
      661 actgttccag ttgagtacgc cggtacgcaa tttcagctag cagtctggaa tgcactttgt
      721 gaaattcctt atggacagac gaaatcctat tccgacattg caaatgaaat aaataaacca
      781 gcagctgttc gtgctgtagg tgcagctatt ggggctaatc cggtattaat tactgtaccg
      841 tgccatcgtg taataggaaa gaatggctca ttaactggtt atcggggcgg attcgaaatg
      901 aagacactgc tcctcgatct ggaaaagcga gcttcatctg aaatggatgt tcctcattga
      961 aagtgaatca tctatatggg ttggattatt ttagaggaaa gtaaagacca gtttactgat
     1021 aaacttgaca acttttaaaa tttagcatat cttatacgta acttaataat cgatgcagat
     1081 gtttattttt cccttttaaa atatgtaggc ctttagcatt cttttcatat ttaattttaa
     1141 atattgatag gatgaaaaag tatcctaata aaaaaggaag agaacatgag tcgatttatt
     1201 tgatagtcag gactatatta aaggaaatga aaacatagca taaagtaaag accaataata
     1261 aggtagcact tcaaaaaact tcgctgaagt tagttgaagt gaagccgaca attttcagga
     1321 ttcaatgatc taacataatc attgaaattt tgaagttgtc ggcttttttg ttggaaaaaa
     1381 atagagataa ataaaaattg aaataaataa tagacaaata tgatctgatt gaaaggtctt
     1441 ttgaacaata atgagtttta aaaaagggag aatttagaat gttagtttcg ctgagtttgt
     1501 catcattatt aacattattt tttattatgc ttatggcttc tgggataagt ggactattgt
     1561 ttttacatcc gcgagtaccc ttgagttttg ttcgcattca tattgggatc ttggctttac
     1621 cacttttggt ttccttactg attcttgcca atagtggtgt gagtggaaat gttggccctt
     1681 ggcacttaga ttccttagct tgtttaatga ctttctttgt tcttgcaatt ggattcatca
     1741 ttcagcgttt ttctgtacgt tacttaatgg gggatcgatc ttatcgaaaa tattttacgc
     1801 tttttacttt cacaacaggt gctgcttcaa tgacatggtt aagtggcgat ctccgcttga
     1861 tggttctatt ttggggagca actcttgttg gtttaacctt acttattagg ttaaacagtg
     1921 cttggcaagt ggctagtgaa gcagccaagg tttctggccg cttatttttg ttaagttggt
     1981 tttctttgtt ttttgcgatg atgtggcttt ttcatgccac aggtcaatgg cagttatcat
     2041 tggttgtaat aaatgaaagt ttagctgggc tgggagaatg ggagagaaca gggattcagc
     2101 tattgattgt actggcggtg atcattcctg cagctcaatg gccattccaa agatggttgg
     2161 ttgagtctat tgttgctcca acccctgttt ctgcgattat gcatgcaggt ttagtaaatg
     2221 ctggaggaat aatactaact cgattttcac ctctatttca tggtggtatc gcttcgatta
     2281 tcttacttct gcttgctggc atttctgtat tgattggaac tggaattagt ttagtccagg
     2341 ttgattataa acgccagtta gtaggctcca cgattggaca aatggggttt atgctcattc
     2401 agtgtgcatt aggcgcctat atagcagcca ttattcatct tattttacat ggtttattca
     2461 aggctacgtt gtttctacaa gctggttcag cagtagggcg tcatgaagta tcggctcgta
     2521 ctaatgaaag aacatcctat ttatgggtca tggctggtcg gattttatcc ttagttatag
     2581 gcgttgcttt ttggctcgct gctcctggag agggatatca attcattagt gcgctgatct
     2641 tagggtggtc attgtccgtt tcttggactc agcttgtcgc ttttggagag ggccgaattg
     2701 gccgaattgc cggcttaact gttttaggag gagcagccct cgtatatttt atcattcata
     2761 accttttcta taagtggctg catacaacca tttttcaaag tgttcaacct ccaatgtcag
     2821 ctgtcatgat tgtcgtatgt ctcttactct ttggcagtgc tttaggtacg tgggttgctc
     2881 gtcatcgttc ttccgttttt ttcgcggtac tctatctttg gttagtccga ttaggtgaag
     2941 caaaaccaaa gtcagtagag agtcacccag actaccttaa acaatatatt tcataaggag
     3001 ctaatctgag atgggcatta catccgtatt aacgaaagat aatgtaaaaa agatagatac
     3061 agatattgat gttcaagaaa gggatcttaa cgttttcatt acatctgcca gccgagtgat
     3121 tgcgccactt tggcctattt ctacatttgc tgcacgtaat ccgtggatgg gacttgaaaa
     3181 ccaacctttt gatcaggttg caagttggtt gaaaaacact cgtgatgttg atatataccc
     3241 tagtgcgtct atgatccgtt cagcaaagaa taaaggtgag attgatgtag attttgtgga
     3301 aatggggctg cagcgttggc ttgattcaca ttcctatcac atcccacggg acgtagcaga
     3361 gcgattttgt catgctgcat taaagttaga tcccctgcct tccgaccttt tatcatcaca
     3421 tgagctggag aaattagtag gtgaatgtag tggattggat catatcgaga atgtgtttat
     3481 gcagccacta agttcgtata tagagaatca agatggtgaa aggctagtca atatactaga
     3541 tcatcatgtc attaaatgga gtaaattata tcttgatgac tctcaagcag gctggacaat
     3601 gcctaatcgt gaggaaggtt tctatcgtgc ttggcagcat ctcattcaat atgatccagc
     3661 acttagcaaa aagcagcgag aaagggtaaa aggttggccg aaagaggcac atttggcttt
     3721 acaggaagcc ttattcgcac tagaaatccc agagtcagaa atccagactt atcttgaagg
     3781 tcatttactt tcattacctg gatgggcagg gatgatgctt tggcgctccc agcaatcgag
     3841 ccacgaacat gcactcctaa cagaatattt agcggttcga atatccatgg agtgggctct
     3901 tataaagcca tacttacctt tgactaatga acgatctaag aaaacaattt caattgctcc
     3961 ccttatagca gcttggattc attggggtgg gcttacatta gaagaatggt cacagatgac
     4021 ggccattgaa caaaacgaat atttatcatt tgcctacagc tttgatgaga aacttcgcaa
     4081 gaaactttgg ttagaagctt gggagcaaac gtacactgat cgattaagcc agaagatcat
     4141 ctcgaaacaa cgtgaaaccg gcggtaaaaa atctgcatta gctcaattag cattctgcat
     4201 cgatgtacga tcagaacctt ttcgtcgtca actagaaaaa gaaggcccgt ttgaaacgat
     4261 tggtattgct ggtttcttcg gggtgccgat tgcaacttgt gaacttggca gtaaacacag
     4321 tcatgcttcc ttaccgatca tacaaaaacc gcaaaataaa ataaaagagt tcgcagatga
     4381 ggatgtattc aaaaaataca atcaacggaa gcaagcaatt cattctttaa gccatacctt
     4441 taaaacgatg aagcagaatg cgctttcgag cttactactg cctgagctaa gtggaccttg
     4501 gcttactctg caaatggcag cccgtagctt tgtgccaaga aaggcgggtc gtttcattcg
     4561 taatctccgt gaggcttggt tgcgcaaacc tgatacaaaa ctctcgcttc atcatgatac
     4621 tacagaggca gaaatacctg tgggttttac tgatgaagaa aaagtgaact atgctcgcca
     4681 agcattaaaa atgatggggt taacagaaaa catcgcaccc ttggtcgtga tctgcgggca
     4741 tggcagtcaa agcactaata atccttattc tgcagccctt gattgtggtg cctgcggtgg
     4801 agcggccggt ggatttaatg caagagtttt agctgcttta tgtaatctat cagaggtacg
     4861 agaagctctt ttaactgaag gaattaaaat ccctgaggat acggtttttg cagcagctga
     4921 acataataca acggtggatg aattacattg gctttatgta ccagagcttt ccgaagctgc
     4981 acaagaagca tttgaacaaa ttgaagctgt tatgccgaaa gtgagacatc atgtaaacgc
     5041 agaacgtcta gcccaattac cgaatttcca atcgaagcta aaaaatccga aggctgaggc
     5101 aaaccgattt gcggaagatt ggagtgagat acgtccggaa tggggactgg ctcgtaatgc
     5161 cgcttttatt atcggtaaac gtgaactaac tcaggattgt gatttggaag gcagagcctt
     5221 tctccataat tatgattgga agcaggatga aagcggtgaa ctcctagcaa atattattgc
     5281 aggacctggt actgtagccc aatggattaa tttacaatat tacgcatcaa cggtagcgcc
     5341 tcattattat ggcagcggaa ataaagcaac tcaaaccgtt actgcaggtc tcggcgttat
     5401 gcaggggaat gcaagcgact tgttagccgg actgccttgg caatccgtca tggaatcaga
     5461 tcacgaggcc tatcattctc ctcttcgttt attgatactc atccaagcac ctagagaata
     5521 tgtagaacgg ttattaaatc atgactcagc atttctgcaa aaagttcaaa atggatgggt
     5581 ccgactggct agtcttgatc cagaaggatg ttgggaaagc tggtaatgat gaatctaagc
     5641 atttatcaaa tggatttgtt actcaataca aaaatgataa acataaggaa gaggtgtgct
     5701 gtatgaatgt aaaccaaaat aaaaaagtat tatttttgac ggatattgaa aacggtttgg
     5761 agcctatttt acaagaagcg actaacactt ctgcagagaa tatgttgact atacaaagct
     5821 atggtgccgg tatttcacat ccttatggag aaatcatgag atctgttatt tttgcgattt
     5881 accaggaaga tgttgaggag atttttgtag taggaacaaa agataagaag acttccgcag
     5941 gtaatgaact aactcaactt gaaacaatga aagataaaat acaaacattg gattatctct
     6001 ttcaaaattg caagcctgaa tttttaggtg gtacggtcga tgaatggcta aatgaaaata
     6061 gcagtgacac cattgaaaaa agtgttgata tgattcgaca tcatccacta gtgccgtcac
     6121 atgttaaagt tcgaggttta ctcgttaatc ataaggatgg aaaaccctca attatggagg
     6181 gtcctgatgc taaaacaggt caagccatac ctgatcattg cttgtcatga tgaaatgcag
     6241 gttcaacttc taaacaccat atatggagaa agcagttcta aggagattgt atgagcgcta
     6301 atttaactga ttttgtcacg aaaacaatag aggacatgaa ctcgtttgat cgtgaaaata
     6361 tggaatgtat gaaaaaacta attagaaaag caattgattt ttatcatcta aagtcttatg
     6421 aagaagttga ggaaacccat tcaggaaatg ttcgattttt gcatgtccac tctatgatgg
     6481 aagaaaatat gttatccaaa atgatagtgg tcacaagaaa cggtaaaact gatttggata
     6541 ttgaaggtgt atatgaagga tatgttgtaa gagaatatta atgagacgaa atcacaaata
     6601 gaatatgcca atttttttgc tcaggagatg tattagatat gaaaaagtcg aagggttcta
     6661 ttgaatcaga gatcagtaag tccattactc aatgggagaa ggattatctt ggacgggggt
     6721 ctgtatctgt taagactgat atactgcggg acatgatcat cgtcaattta aaagggattt
     6781 taacaccagc cgaatatgta gtttgtgggt caaaagaggg tatgttatct atcaaacaaa
     6841 ctcgttcaga gttagtcgaa tcaggtatag aaggccttaa ggatattatc ttaaaaataa
     6901 ccggagaaaa agtgaaaagt tttcatactg atttaagctc ccggacaggt gaacgagtga
     6961 tggtgtttaa attatgtaat gatctagaga aaaatttgga aaagatctta taatctaaag
     7021 aaaataaaat gttttgacgg tatggaatct gttgtgaatt gaacataatg aactgccgct
     7081 tcttttgttt tacaattatg gcatcattga taacttttat tcatatccta agcggacata
     7141 aagagatgtc aattcatagt atactgactt gttattcctg tcgaaagatc taacatccgc
     7201 tgttgttatg agcggatgtt ttttacatct aaatttgatg ctggtgatta gtcacttgaa
     7261 caatattaaa ttcattttaa ttgaaaacat ccttgtcacc tgccgggttc ccccaagtgt
     7321 ttagtgacat gattatgaga ccaatttcgt aaagcttgat gataaattta agaggtgaac
     7381 aaaattgata tgctgtcttc agtttcattt cacggaatta gctttaatta aatatatcca
     7441 aaaaacggat tgacatatcg gaatataacg atataataat ccatatggaa ccaattgaag
     7501 tattcaaagc cttatcaaat gaatcaaggc tgcaaatttt acaatggctg aaggagcccg
     7561 atcgtcattt tgcaccccat gaagggattg atatgaacac aatcggggta tgtgtcagtc
     7621 aaataacaga caaattgaaa atgacgcaat cgacagcttc tcaatatctt accatccttt
     7681 taagagccgg cttgattaag gcggagcgta ttggaaagta cacatattac aaaagagatg
     7741 aagaagccat tgggaaactt gctgactttc ttaaaacaga gatataaaaa taaacatcaa
     7801 aagatgttta tttttacacc atacatatcg acatattacg atgtgtttat tttttataat
     7861 aacatatcga taattcgtga tatgtttatt aataattaag gagtgaatgt tttatgtcta
     7921 acacttggaa aatttatatt ttagccattg tcagcttttt agttggaacc tcagagtaca
     7981 tcatttccgg aattttggat caaattgctc atactctcgg gatcacttta gctgccgcgg
     8041 gccagcttat taccattttc tcacttgtat atgctctttc tacacccgta cttatggcgt
     8101 tgacagcaag tatggataga cgcaaattga tgatgtatgc cctaggtttg tttgtgttcg
     8161 gtaatgtcct ggcttttgta ctgcctggtt atggatggtt tattgcagcg cggatcatta
     8221 tggcgatggg agcaggtgtg gtggttgtca ccgccttaac gattgccgct aaaattgcat
     8281 cggaagggaa gcagggaagt gccatcgcta cggtcgtgat gggatttacc gcttctttaa
     8341 tcattggtgt tccgcttgga agaatgatag cagtagcatt aggctggaag tctgtatttg
     8401 gagcaattgc tttgttggga ttgatcgcaa tggtcgttat tttctttact cttccgcata
     8461 ctgaagggga taagcctgtg cctttgcttc aacagcttgc tcttttcaaa aaacggaaag
     8521 tggctatggg attatcaatc actttcttct ggctcggggg atattctgtt gcttacactt
     8581 atttgtcacc gtatctcttg aacatctcag gtataaatgg caagctgctc agtggtgttt
     8641 tgcttatatt tggaattgcc agtttggttg gatcaaagtt tgggggatat agcaccgata
     8701 aatggggagt gtcctttaca ctcgttggcg ggatgacgtt gcatatcgtc acactgattc
     8761 ttctgtcact tgttactcat tcctatatcg gagtgttggt gattctcata ttatggtcgt
     8821 ttgccgcatg gtctaccggt ccgacacagc aatttcacct ggctacaata gaaccggaaa
     8881 tgtcaggtgt tttgcttagc atgaatcagt caatgatgca attcgccatg gcggtcggcg
     8941 caggaatagg aggggttttt gtggaaaacg tatcattggc ctcgattacc tgggttggtg
     9001 cgttaggggt tatgattgca attattacat cattgacgat ttttcattca caaccgaaac
     9061 agacgttaaa agatatcaat caataatttc gaaagatcta acatccgctc gttatacaag
     9121 cgggtgtttt ttataagcgt tcaaagtcag tccatgcatg agccttccaa gggccgacat
     9181 cgttctgtat gtgtcgaagg cgcactgaag ctgaaaggga tttcttaagg ctttgccgct
     9241 gaagtacggt acgattgcct tgatcgaaca ctggaaacac aagagaacgt aaacctgaac
     9301 atccgcgtaa acgtcaagga agttgccact tggggagtaa acacttgcat catctcgctg
     9361 aaaggcctag acaatgcgta taacagattc gtactgtggt agtaacccaa cgcttactct
     9421 gttggtttct gttgtcggtt gcagctgatt gcttactaat gctgccctgc atctcggttg
     9481 tgatgtcgat aagcagcgta actttgtgaa gagtgttact gtggagtaag aagtttaacc
     9541 cctttggata ttttagccga aggggttttt agtatagata tttgatttaa attacaggag
     9601 acttcattca tttaactaaa gtcattgctt tcttaatcac taaagtttat ttgaaaataa
     9661 tctcttgatt tattttcctc gaagagattg tttgtcaatc tattaggcat cagaattttt
     9721 ataacagaat ggatcgtctt tttgacgttt tgtttataga acaagaaaat attcaaaata
     9781 taagtgaaaa attaggggtg agctcctgtt tttctcgaga ggatagcttg tcagcttttc
     9841 tatttttaaa gggttaaaat attctattta tactaattaa tgtaattttt aggataatat
     9901 acaaaatccc ccttacttcg acaattgcaa tctggtatta tcgtatcgca tgggagctat
     9961 gtcaatagac tctatgcaaa aattgagagg aggtttactt atgaaaagaa accaaaaaga
    10021 atgggaatct gttagtaaaa aaggacttat gaagccggga ggtacttcga ttgtgaaggc
    10081 tgctggctgc atgggctgtt gggcctcgaa gagtattgct atgacacgtg tttgtgcact
    10141 tccgcatcct gctatgagag ctatttaaca tttgagaata gggagttgag cgtatttgct
    10201 tatactcctt attttctctt aagggggatt ttatatgtca tatgatcgtg ttaaagattt
    10261 tgatttgcca gagttagcgg ttcatttaca gcctcatggt gctgtaatga ttgatagaaa
    10321 aagtatgttt tatttcagac tcagtggacg tggagcacag ttggcgtttc tgttatcaaa
    10381 aaacaaaaac cttcataaaa cggcacgtat ttgggagatt atgaaaaaag aagagatgag
    10441 tgctgaccaa ttaaaagaag agcttagtgc ccatccattt acggaggctt ggacggaagg
    10501 gctgttagat cagcctttac acgtttcggg ttcgctagat tcatatttac ctattagttg
    10561 taccttgcag ttgacaaatg cttgtaattt aagctgttcg ttttgctatg ccagctcagg
    10621 taaaccatat cctgaggaac tatctagtga acaatggata ttggttatgc aaaagttagc
    10681 agcccatgga gttgctgata ttacgctgac cgggggtgaa gcaaagctga tcaaagggtt
    10741 taaagaatta gtcgttgttg caagttcgtt gtttaccaat gtgaatgtat ttagtaatgg
    10801 attgaactgg cgagatgaag aagttgaatt acttagtcac ttaggcaatg tttctgtaca
    10861 gattagtatt gatggtatgg ataatacaca tgaccaatta agaggcagaa aaggcggctt
    10921 taaagaaagt atgaatacca ttaaaaaatt atcagaagca aacattccag tgattgtcgc
    10981 tatgaccatt aatgagtcca atgctgatga agtatcagat gtggtggagc aatgtgccaa
    11041 tgcgggtgct tttatctttc gtgcaggaaa aacgttatct gttggacgtg cgacagaagg
    11101 ctttaaggct ttggatattg attttgaaga aatggttcaa atacagctta gggaagcacg
    11161 tcataaatgg ggagatcgcc tgaacataat tgattgggag cacgaagaga gttcgttcac
    11221 aacagatttt tgtacaccag gatatcttgc ttggtatata agagcagatg gatacgtaac
    11281 tccttgccaa ttagaagatt tgccgctagg gcatatttta gaagatagca tggctgacat
    11341 tggttcacct gctcgtttgc ttcagttaaa atgtgaagct aaaaattgca aatgtatagg
    11401 gaaaattgag ctatctgaac cggacttgcc ttttcaaaaa gaagtcaagg cagggattca
    11461 ggaatgaata gtctatcatt ggtgttctgg agtattttag cagttgttgg attactgtta
    11521 tttattaaat tcaaaccccc aacaattgct tcactactct taagcaaaga tgaggcaaaa
    11581 gaaataagca ttcaatttat aaaagagttt gttgggatag atgtagagaa ctgggatttt
    11641 tattcggtat attggtatga ccacgataca gtaaataaac ttcatcactt aggcatactt
    11701 aagaaaaata gaaaggtttt atatgatgtt gggttggtcg aatcatggag agtccgtttc
    11761 gttcaccaga atcaatcatt tgtagttggt gtcaatgcca atcgagaaat cacttttttt
    11821 tatgcggatg ttccgaaaaa aaccctttcg gggaagtttg aacaagtttc tccagagaca
    11881 ctcaagcaga ggttaatggc ttcacctgat ggactttggt ctagagcaaa tatgactggt
    11941 actggtaaaa aagaggagga ttttcgcgag gtcagtactt attggtacat agcggaagcg
    12001 ggagatattc ggctcaaggt gactgttgaa ttacagggcg gccgaatttc ttatattggt
    12061 actgaacaag aaatactaac agatcaaatg agtaaagtca ttcgagatga acaagtggaa
    12121 tcgacattcg gagtatctgg tatgctgggt tcagctttag cgatgatcct tgcgattctc
    12181 atccttgtat ttatggatgt gcaaacaagc ataatcttca gtcttgttct gggtttgttg
    12241 attataatat tccagtcatt gacgctgaaa gaagatattc aattaacaat tgtaaatgct
    12301 tatgatgcaa gaatgagtgt caaaacggtc agtttattag gtattttgtc tacacttctt
    12361 acaggattat taacaggatt tgtagtattt atatgttcat tggcaggaaa tgcgcttgct
    12421 ggtgattttg gatggaaaac gtttgaacaa ccaatagttc agattttcta tggaatagga
    12481 gcagggctca ttagtttagg agtgacttct ctgctgttta acttattgga gaaaaagcat
    12541 tatttacgaa tttcacctga gctttctaac cgaactgtct ttctatcagg ttttaccttt
    12601 aggcaaggat tgaatatgag catacaaagt tcaattggag aagaggtcat ctatcggcta
    12661 ttaatgattc cagtcatttg gtggatgagt ggaaatatcc tcatctccat tattgtatct
    12721 tcctttttat gggcggtgat gcaccaagta actggatatg acccaaggtg gatacgttgg
    12781 ctgcatctat ttatattcgg ttgctttctg ggagttctct tcatcaaatt tggttttatt
    12841 tgtgtattag tagctcattt cattcataat ttagtactcg tctgtatgcc gctgtggcag
    12901 ttcaagcttc agaaacatat gcatcatgat cagccaaagc atacttcact ctaatgatta
    12961 ggagaagatt tgatgcaatt gatgcaagta caaaatttaa gcaaatgcta tcgaaatggt
    13021 gatggggttg aacatttgtc tttctcaatt caacgaggag aaatcgtggc gctattgggg
    13081 ccaaatggag ctggaaaaac aacgacaatt cgatgtttga caggtctcta taagccggat
    13141 aaaggagata tcctcattga gggttctcct ccaggacata taaatgttca aaaaaaagtc
    13201 gcgcttattc ctgatcagcc atatctgtat cccgctttaa ccgctgctga acatattcag
    13261 tttagggcaa gaggatatca tccaggtaaa aaagatgtaa aagaaagggt ttatcatgca
    13321 ttgaaggaag tgcacttgga ggagaaagca aaccaattgt gtggtcagct gtcaagaggc
    13381 caaaagcagc gggttgtcct ggcgggggcg attgttcaag acgctttgct gtatatatta
    13441 gacgaaccga ctgtgggcct tgatatccca tcaaaacagt ggctctctaa ctggttaaaa
    13501 actaaaaccg atcaagggtg ttcagcattt gtatcaactc atagtctaga gtttgtttta
    13561 gagacagcag acagggtgat attaattaga gacggcaaac tcatgcagga tttgtatgtt
    13621 cctcaatttg aagaagaaca agcggaatgg agaaaagaag tgattcgtct tctaggggaa
    13681 tggtcagatg aataatatca tttctttttt atggcttcag tcaaaaaggc gttttgtcag
    13741 tcaaggtcag gaaaaaaaaa tgcctttttt gatcatgctc ctttttgttg gggccatcgg
    13801 atttcaagta agttttgttt ctagatctac gacatgggat atgagtattg ctggttgggt
    13861 acttacaggt gtttttatcc tttatacggc atttggcctt ttttcaaatc gattaccaag
    13921 tcaaatggca gatattatat ggctttatgg cactgccaca tctttttcaa aagttgtgta
    13981 tagtgtttta tttttcagcg tcacttggaa ggcgttgctt tggatcatct cagccatatt
    14041 cggtgatgta ttaattgtgc ttctgtctgg tgatcatatc aatttattag gccgatccat
    14101 aatttttgta gggctctttt ttatcgctga agtgtggttg atgtcggtct cttgtgccag
    14161 aacagtgaag aaaatgaaaa gggtatacgt tttagtcttt cttctaatgt taggcattta
    14221 ctccatatgt ctttatcaat tcttctttct ccaacattca tctgggatat gggagagcat
    14281 tgcccgtttt attagtggcg ttggattagt gtttgataca ttgtcaccgt tgtatgtggt
    14341 tgtatttatt gggatcatca cagtctcttt tatgacaatt gcttttacga gccgtcaggt
    14401 agaaatgaag gaatcgttgg tgaaagaagc tgaattctgg gaggaatttc aagaacgtca
    14461 atttggttca ggtcaaatta tacagaaacc aaaaacgact tggtggggct tgcaaggtct
    14521 aaatggcatt tggtcttttc tgtggttgga actgttgctt tttaaaaaat atttattttt
    14581 tcatagcatt catacggtca tgctcagtgg cgtcttttat gtcgtcattt tcatgtatcc
    14641 agaatggttt tatcttcttt tctttcttat cgtctcggca gtcatgttaa gttcctatta
    14701 ttcaggaatt gtcagacatt ctcaatcagg cacccttcat ttattccccg gtgccctttg
    14761 gaaaaaaatc attattctag agctgacgaa tacagtctgg ttgtatattc tttactgtgt
    14821 ctctattact tttatggcag ttgggaattt agtttattgg tatatatatg gcttagggat
    14881 atatatatgg ttcatgacaa taaggctttt tgcttttacc catacaaacc gaaacgatat
    14941 taagctttca ttgcctcaat actacaagtc attttttatg gcattaggcc tgagcggcat
    15001 ttgtttgtat gtcattcatt tattgactgc tgactggtat acattagtgg tggtcgtctg
    15061 tatagggagc ctaagttggt gcctgtttta tcgtttcaga tagtggttat gtagagttat
    15121 tgttttaaaa cgaggagagg ggctctttta tgaattcaaa tggtgataaa ttgtcgttat
    15181 ctgttcagaa tttagcgaat acaaatgaga tcacaattgt tcaagcgata ggtgagctaa
    15241 agaaatcggg aaaagatgca ataccagttt tggttgaggc cttaaaagag gaaggctctt
    15301 tgtgtaatat tgctgcagct gttttaggtg agtttgggga agacgcgagc gaagcagcgg
    15361 aggagctatc atgtttatta aaaagtcatg ccgaagatac aagaatggca gcggcgattt
    15421 cattaatgag aatcgggaag cccagtctgc cctttgtcat caaaatcgct caagaaagtg
    15481 aagggcaatc gtgcttttgg gcatcttggt gtattgcatg gattgatccg tcttgcattg
    15541 aacctaagat gtataaatgt ctaaaatacg agcatgaaca tccttcagga atagttgctc
    15601 cgtttgcggc tgaagaggca ttaggaaagc tgattgcttt tcagctgaaa gataaggagg
    15661 actgaaagga tgaaagatga acaaatgttg actgaatggc caagtcattt accatggttg
    15721 aatcaatcac agaatgattt tacatttcca agtgacacat atcttcttct ttatttttgg
    15781 tcaatgagct gtccaaactg tcaccaatta acagacaaag tccttcaaga tataaaagat
    15841 atgaatgtga aagtaatcgg agtacatgtc ccttatatag aagaagagaa atctatggag
    15901 gttgtcttga cgtatgctct tgatagggga ctagctattc cgattgtatt agaccaaaac
    15961 tatgagatcg tcacaacttg tcacgtacaa ggcatcccca gcttttgtct attaagtaaa
    16021 tacggtcaga tcattactaa aacgatggga gatgttggtt gggataagat gttaaaaaag
    16081 attgcaggct tgtgaaattt tccgtcttgt atgtgcgaca aacggttgaa tattatgatg
    16141 aaacggtcct tcctataagc aggaaggttt tttaatgaaa tattttttta ttagtaggta
    16201 aattcatcaa atgttctgct atgctccaaa tgtacacctt tccgtaaggg caaagttaaa
    16261 tgtgaaaata aaactgttcc aaagttaatc agaaatttat tttcatattg tatcctttca
    16321 gtatcaagtg aaaggagcat catatgaaaa cattatggaa agtcctcaaa attgtttttg
    16381 tcagcttggc tgctttggtt ttgcttgtat ccgtctcggt atttatttat caccatttcc
    16441 agctaaataa ggaggcggca ctgctgaaag gtaaaggcac agtagtcgat gttgacggta
    16501 aaaagatgaa tgtgtatcaa gagggaagcg ggaaggatac gtttgtgttt atgtccggtt
    16561 cggggattgc tgcgcctgct tatgaaatga aggggctgta cagcaagttt tcaaaagaaa
    16621 gcaagattgc tgttgtagat cgggcaggtt atggatacag tgaagtgtct cacgatgaca
    16681 gagatattga tacggtattg gaacagacga ggaaagcgct tatgaaaagc ggaaataagc
    16741 ctccttatat tttaatgcct cattcgatat ccgggattga agcaatgtat tgggcacaga
    16801 aatatcctaa ggaaatcaag gccattattg cgatggatat tggattgccc cagcagtacg
    16861 tcacgtataa attgagcgga gttgacagat tgaaagtgag agggttccac ttgttaacgt
    16921 cgattggttt tcatcggttt atgccttccg ctgtatataa tcctgaggtg attcggcagt
    16981 cgtttttaac tgatgaagaa aaagaaatct ataaagccat taactttaag caatttttta
    17041 atgcagatat ggagcatgag cttttacagt cttaccaaaa cggcagcaaa tctgtgaatc
    17101 tgccggcacc aaaggagact cccgtcttga ttttagatgc ggtctctgac caaaatagac
    17161 attcaaagta tgctatacaa aaccgaaaag actatgaagc gtttgcggct caattcaata
    17221 ctgccgatat aaaggaactg aggggaacac acagtattta tttatatcag cctgatcaaa
    17281 tatataaact ttccatggag tttatgagaa aggttcgcta ggatgaaggg ttatcatatt
    17341 ttaatcgttg aagacgatgt gatgattggt gatttgctgc aaaagatttt gcagcgtgag
    17401 ggatatcgtg tgatatggaa aacagatgga gcggatgtgc tttcggtgat tcagaaggtg
    17461 gatttggtca ttatggatgt gatgctgccg ggtgaagacg ggtatcaaat gtctgcaaaa
    17521 atcaaagagc tggggctggg cattccggtt atttttctct cagcccgcaa tgacatggac
    17581 agcaagcttc aaggtttgca gatcggcgag gattatatgg taaagccctt tgatccgaga
    17641 gagctgctat taagaatacg gaatatgctt gagcatcatt atgggacctt tacgcaaatc
    17701 aaacatttgt atattgatgc ggtaacgaaa aaagtgttca atgaaagcct gcatgatgag
    17761 gtattattta ctgcgattga gcggaaaatt ttcttttatt tatatgaaaa tagagacagt
    17821 atcctgacaa aggaacattt ctttgaatat ctatggcagc tcgaagatag aaacccgaat
    17881 attgtcaatg tgcatattaa aaaaatcaga gctaaaatca atgatcaagc gggtgagatg
    17941 attgaaaata tatatggaga agggtatcgg ctgaataccg ttgtgaagaa atgaagctca
    18001 agacaaaata tcagttgtta ttgtttacgg ccgtcattag tgttccgatg ctattgctgg
    18061 cggtcagtgt tttgatgtcg gtgatttatg acagcatgtt taaaacgatg aatcatggta
    18121 tgccctttca caggtcgttt gcgtacccgg caatgatcgt tgtatttttg atatcgctct
    18181 tattgttagc ttttttattt tcaaagtcga ttcattctct gttgcataaa atcaatctat
    18241 taaatcaaac cattcggcat ttggcgagtg atcaaagggt gcccgataaa attgaagtga
    18301 agcgtgcgga tgaaatcggg gaactgatca agtcggtcaa tttgttaatt gaacggacga
    18361 catatcgtga actggagctg agacagcaag aggaaatcaa aaaggagctt ttgcaaaaac
    18421 tgcggcatga cattaataca cctttaacgg ctctcagact gcagttattt tatttggaag
    18481 accaatgtca tggtcaggct gtattcgaat cattgtatca gcaaatcgaa tatatctcgg
    18541 aattaaccaa tgaattcaat ctatattccg ctgagacgct ggaaagctct tatattgtaa
    18601 atgaagaagt gcgtctaaac gagctattag aaacagcggt gaaaaagtgg gattatttat
    18661 acagtatgag tgggattgag ctgcactata agccggcaga tcaagatgtg atatggatga
    18721 gcaacgcgtt atggctgcaa aggctgtttg ataatatttt tcaaaatacg ttaaggcatt
    18781 caaaagctaa aaagatggaa gtcacgattg aacatggcga tgtttttatt cgtgatgacg
    18841 gtattggatt tgatcggaat gagagcagtg agggacttgg gttaaagatt attgaggata
    18901 catgcaggct gcttgcgatt acttatgagc tgcatacaaa tgataacgga acggggttct
    18961 tgttttcaaa agagtgaccc cgctgatgtt tttctttctc ctataaaatt tatataatag
    19021 ggagaaagaa atggggtgaa cagcatatgt ttaaaaaaat catcaaaacg attaagtacc
    19081 tctcaagcag ttctagtgac cgatatcgca gacaccggca ttacagcagc agtcggcgca
    19141 gacattatcg cagctacagc agcagttcgg gcaaaagaag acactacgac cgttatggcg
    19201 gcagtcatcg ttacaaacgc cggagctaca gcagcagtta atccaaaaaa agttcttgtt
    19261 ccgcttttgg gacaagggtt tttttatgtg accgattgaa tggcccggtt tagatcctcg
    19321 cgaatggaag cggtgtgctg atactcttcc tcaatgccca ataatctttt cagcagcaag
    19381 gttacttcct ttgtcagtgt taattcctcc agccaagtgc catttttctt cttttttcct
    19441 ttatattgag agtacagcag gaataacagc gtttctccga gatcgaagaa gtcatcctgt
    19501 tttcgtacct ttatttcctc catttcttca ggagtcaatt gtttggcaag gccgaaatcg
    19561 atgaggcaga gcctgccgtc attgatgatg atattaggcg ttctgatgtc gctgtggaag
    19621 ataaggcgat catgcaggta ttctataatc tcaagcagct gcgaaatcag ttgtaacgcc
    19681 ataagctctg tgaacggctg ttttcgaaaa aataataatt cttctatatt ctctccctca
    19741 atgaactgca tgacataata agcctgtccg tctatgatga actcatctat gaagcccgga
    19801 atttgcgggt ggtgaatgct attgagcagt tttatttcct gttggaatcg gactttctct
    19861 ttttcctttt tcgcttttgt cggccgaagc tgttttaaga cataaggtgt ttgagttagg
    19921 atatcggtgc acaaataaac caaaccgtag cctcccatac cgaggcactc ttcgattttg
    19981 tattgatgat ttaagataac gccgttcttt agagggcggt caaatagcag tttttttaga
    20041 agttttaatg ccatgtctgc acttcccttg gttgtactga ctatagttta ccttctagac
    20101 tgagaataaa aaagagccgg ataaccggct cggtataagt taaaactgct ttgtcacgtc
    20161 gtattcataa tctatttttg cttttacgtt gctcatcgtc gatctggctg tcgctaatgt
    20221 attatattta aaactccata cctttgccac actgagttga tctgacaaag agatatcata
    20281 agaccctgaa gtcgagctgt ttacaagagc acggcgccat tcgttgtttt cgctcgtcat
    20341 gatcaggtgg cgtgtatttc cctggcttgg tgtttgagtg gcggttgtct gaactctggt
    20401 tacaatggca tcacgcggta tcccagattg gtttgttaaa tcaaccttga tcacgctgga
    20461 atcagaacct gaggggctaa ggcttgtatt tcctttattt tcagcaacgc cgctgaattg
    20521 gaatgttccg ctgcctgatt tgattcggtc ttcaattgaa agtgtaaaat acatgtttcc
    20581 ggtataggtg cctcgtgaca ctttcacata aaaggtatct gtcgtgtttt gggcgtctgc
    20641 atttgaataa ataaaagaag aaaacgtatt agggttaatg acttctgtcc cttgagaaac
    20701 aggtattcta ttcttatcat aaatttcaat tttcatccct gtatacgcgc tctggtatgt
    20761 actcctcacg tatacttttt ctcccttatt agccgtaaaa gtgaaatagg cttcatcttg
    20821 accagcttcc agtattgttg tatcgatatt tttatatttc caataaccga tcggcattgc
    20881 ggtatcaaat gaattgtttc ctgtgatagc agtgactccg acagctgatg ccgaatacgt
    20941 aaaggtgaat aagacagaca gcataacagc gaatggaata agccattttt tcaccatgca
    21001 aacaacctcc ttttatttcc atcatacata ataacgattt aggtgtaaat aaatgttttt
    21061 tgaggttaat atatacatta tctttgccga taaaaaagaa taagagagaa tactcgggag
    21121 ggaattcaat gcgtctgaat cggcaattta tccgcactca gctgatggca cagaacatat
    21181 tgagcaagaa tgcgcctgcc aaacgggaga atgcgactga aaatccagcg gcagttctgg
    21241 aaaaggcata cagcaggctt aagtcacaat cttcaactgg gggaatcaat cagttcaatt
    21301 attctaaaac cagcgtgtcg ggaaacagcg ggacgttcag caaagtgtat caatcagcga
    21361 atgatcgaac agtgacagac acaggggaag aaacagtgat tcaatgccaa aacccctatg
    21421 aatctgagag tgatatcaga atcaaaatac tagatgaaaa atacagcagg atgaatgcga
    21481 ttaacaaaac aaagtctgat ccattaggct atattaagga taagtaccaa aattcaaagt
    21541 ctccttattt cagaagtgat ctgtcagctg cagaaagaca ggccgcttac gataatgaaa
    21601 cagaatggct attcaaaggc aaggcccaaa actataacct tcaggatgct gcgtttcgga
    21661 atgtcacatt tcatggggaa gtggaagctg agaatgaaaa ggtgtatcag cggggacagg
    21721 ttaaccagca gctgcaagtg ctgttgaatc gaaaccatat tcatattcca gaggggacag
    21781 agctgacgtt tacaatcaca ccgattgact atcaggtgcg ggtaagcggg acagacgatc
    21841 aggatctgat caagcaaatt gagcaagtgc tgcaatctgg agacaacagc aaagaactat
    21901 ttttgcacat catgaaaagc caaagcagtg attcagcaca attttccgaa gaggcctatc
    21961 aaaagtatca ggctgctcgt gagatgtatg aagttacagg ctaccatttg aaggatttag
    22021 aagtgattga tgggcggtac gtcacgcctg agggacgtga cttaatggat gtatataagg
    22081 aagagcttga aaaagatcca gtgcagaaac aaacggcttc ttatgctata tcttactacc
    22141 gttcagagct cagtaaaatc gcggaagccg ggtataatgc cattccggat ttcatcctat
    22201 caattgatta cagcaatgga tctctgagag atgtgggaca aagcaagagc tatgggaccg
    22261 gagataccgg gtggcttgaa gcattaaagc gtcaaacggg tgtgaatgat taggtaagct
    22321 gttcatgtag gacagcttat tttttatgag aatctaaggg gcgtattaat ttcaatattc
    22381 aaacaatttt attattttta tataaaagat tttaaaagaa gtgaacgatt caaaactctg
    22441 aacaaaggtg tttacctgaa aaaaacaatt gtattttcca gagaaattta ttatgatgaa
    22501 ataagtaatt taggagatta tataacaatt ttaagtttga attttctgat tgttatcact
    22561 gattcatgtg aaggcaagca ggtctgctgt tttctcattt atgagtattt tgttaggagg
    22621 aggaagagga gtggcaaata aagaattaaa gaggggcctg ggtgcgcgcc atattcagat
    22681 gatcgccttg ggcggtacga tcggtgttgg cttgtttatg ggttctgcca gcacgatttc
    22741 atggactggt ccatctgtcc ttctggctta tgcaatatgc ggaattttta tcttttttat
    22801 tatgcgtgcg atgggtgaaa tgctgtatgt cgagccgagc acaggttctt ttgcgacgtt
    22861 cggccatcaa tatattcatc cgatggcagg ttatataaca gcatggagca actggttcca
    22921 gtggattatc gtcggcatgt cagaaattat cgct
//
