LOCUS       NZ_CP060742            20846 bp    DNA     linear   CON 27-APR-2024
DEFINITION  Streptomyces alfalfae strain XN-04 chromosome, complete genome.
ACCESSION   NZ_CP060742
VERSION     NZ_CP060742.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces alfalfae
  ORGANISM  Streptomyces alfalfae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8254035)
  AUTHORS   Chen,J.
  TITLE     The Biocontrol and Plant Growth-promoting Properties of Streptomyces
            alfalfa XN-04 Revealed by Functional and Genomic Analysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8254035)
  AUTHORS   Chen,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2020) College of Plant Protection, Northwest A&F
            University, No. 3 Taicheng Road, Yangling 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018141485.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 05:42:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,240
            CDSs (total)                      :: 7,142
            Genes (coding)                    :: 6,967
            CDSs (with protein)               :: 6,967
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 175
            CDSs (without protein)            :: 175
            Pseudo Genes (ambiguous residues) :: 0 of 175
            Pseudo Genes (frameshifted)       :: 75 of 175
            Pseudo Genes (incomplete)         :: 141 of 175
            Pseudo Genes (internal stop)      :: 22 of 175
            Pseudo Genes (multiple problems)  :: 59 of 175
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:18:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 534093
            Orig. end                         :: 554939
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP060742.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="6"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20846
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20846
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10846](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10846)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(140..985)
                     /locus_tag="H9W91_RS02155"
                     /old_locus_tag="H9W91_02150"
     CDS             complement(140..985)
                     /NRPS_PKS="Domain: oMT (54-157). E-value: 1.6e-08. Score:
                     24.9. Matches aSDomain: nrpspksdomains_H9W91_RS02155_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="H9W91_RS02155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02150"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_062768029.1"
                     /transl_table=11
                     /translation="MTEPTYEKEVRGYFADKAEAYDDVDLQPYWVLSDRLLADALREDV
                     ISALPEDFAFLDAGGGTGRWTSFFAQEAPRSTGVLFDLTREMIKVAEAKAAERGFADRV
                     RFVQGDLADVGETLRGESFDLAFNFHNVLGFVADPEQTIKDVAGLLKPGGLLVSFLPSV
                     WHTAWFNIAVGNIDEAEKALTRRGRFTDTMPDMHLYDVQRIEEMHAAAGLEIDALSGFP
                     NLIYPGYQETQLHGSTEQLVDILAGDDFERVLAMEKRVRKAPGIAGRGNNLFVVARRPA
                     "
     aSDomain        complement(515..823)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H9W91_RS02155_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.60E-08"
                     /label="H9W91_RS02155_oMT.1"
                     /locus_tag="H9W91_RS02155"
                     /protein_end="157"
                     /protein_start="54"
                     /score="24.9"
                     /tool="antismash"
                     /translation="FLDAGGGTGRWTSFFAQEAPRSTGVLFDLTREMIKVAEAKAAERG
                     FADRVRFVQGDLADVGETLRGESFDLAFNFHNVLGFVADPEQTIKDVAGLLKPGGLLV"
     gene            complement(1069..2328)
                     /locus_tag="H9W91_RS02160"
                     /old_locus_tag="H9W91_02155"
     CDS             complement(1069..2328)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014298.4"
                     /locus_tag="H9W91_RS02160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02155"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_211824929.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.7e-07,
                     bitscore: 28.5, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 2.1e-07, bitscore:
                     29.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRVLVCRWDPYILEALRAEGAEVALLFDTFEAAHFHVDEEVLK
                     TLPYVFRINSFDDMDELGQVATQLKNDGWLPDRVVSLSEFSQYGAGYLAQLLGCAQPTL
                     EMALNTRDKRAMKQAVRAAGVTCTDFVSLRTSEVAASVRRTAEEIGFPAVVKPCAGLGT
                     LGTSWVHSEEELTKLLTDLGGDNTEHFLMAERPVSGDEFHVDAIWVDGRSKVLGIMRYL
                     RPRLAIETAGESNGSVLLPREEWAELYADVEEAHRRVNDALGIREGITHLEFFKQPGER
                     EVVFSEIASRFAGGGITATYRALGDDLRIAWIKSVVDPGRPAPYADGEPSRYVGWINLA
                     PSEAGRITAEPTQAEIDAFDYVLETVRPHGVGDDFSDPHPSAWCLHLIYGADSLEQFEE
                     RGRELEKALNSSFRTEPTDA"
     gene            complement(2381..3685)
                     /locus_tag="H9W91_RS02165"
                     /old_locus_tag="H9W91_02160"
     CDS             complement(2381..3685)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="H9W91_RS02165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02160"
                     /product="MFS transporter"
                     /protein_id="WP_076687964.1"
                     /transl_table=11
                     /translation="MNSLRTLRQLPPRARRLIVLNAVNAAGSGVVLPLLVIYLHEMRGL
                     SLTAATGAVAATSVGALVGGPLAGWVSDRLGRVPAVWAALVCAALGAVGYALCDTPTTA
                     LAAGFVQGLGVGGAITWNALMADLVPEEHWPVLFSADFAMVNAMMGIGGLLGGLLAGMT
                     DSLAVFQALFLLDAASFLVTGWLVAREVRRRRSVEPPTGETPPEAAAADQPRSSYRAVL
                     GHRWLVALLVVVLVLFTVGYSQLNSGMPAALLADSRLGPTELGVLFAANTAAVVLVQAA
                     LIGRIKQVTAGVALALLAASWAAFWLLIWAVTGLSGGLVALLVGVIAMVVFAVGESLLA
                     ATGPTLVNSWADDSNRGRFNAAYGFVCSLGFTVGPLVSGRLTDDGHTTSMMLGFTAVLA
                     VLALITVRSRFLPRTPLSGLERTGHEDAAEEDARA"
     gene            complement(3702..5315)
                     /locus_tag="H9W91_RS02170"
                     /old_locus_tag="H9W91_02165"
     CDS             complement(3702..5315)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="H9W91_RS02170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02165"
                     /product="radical SAM protein"
                     /protein_id="WP_211824945.1"
                     /sec_met_domain="PF04055 (E-value: 2.5e-20, bitscore: 72.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGLGPTLKNSDYLATTMLDRQSGDANTAAYLKGTDLEDFGLRRL
                     GFRHNGTDYPLLRPRYYNVPHLTTFAVQEILERAGHHVDTYDATNLWTDDLPAPAPQGD
                     YRAALLSTSFIWTDRDLRHAVQWISATYPGIPIVLGGQYSNLKYTSLMRSIPEIDYIVR
                     GDGEEALPGLLTALEKGSDPETVPNLVYRHSRELLGYRMSPFEYLDLDAFPSPSPKGQW
                     RVIPYESMRGCPFSCKFCSFPAASPKWRYKSAQKIADDWRRYADENGASYISAMDSTFT
                     VPPTRLRELMRLLPDVGVGWEGYSRANVLKTPELIAQLAASHCQFLSIGFESMSDSTLR
                     YMNKKVTRKDNLRAFRLLNEGGLGYRCSFMAGYPGERPEDFAETRDFLSEEYAGHFMLS
                     VFSISDETMPLWEDKEALRIEVHDPDDPDYSWSHIGMDVHTARRLNHTTLDQVRQVNDR
                     AVLRLWQADYQHLLMPQLGRWENIAVEKAVERIGMTPRDHSDPAAAVPQIRKQLDVLSR
                     YGVALYPRADVLSDRPLFHT"
     gene            complement(5379..6416)
                     /locus_tag="H9W91_RS02175"
                     /old_locus_tag="H9W91_02170"
     CDS             complement(5379..6416)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550853.1"
                     /locus_tag="H9W91_RS02175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02170"
                     /product="asparagine synthetase A"
                     /protein_id="WP_237283484.1"
                     /transl_table=11
                     /translation="MSTYMTQTQPLTAPGTWRTPDEHFEVALTHPWYRLLLRLTDVMQR
                     ATVEFWAGRDVRAAYLPVTTGSISSPMGLGSDSVPVRIDLEGVPTYLADSMQFLLEYSC
                     RMWEKGSYYVMPSFRGEAPDPTHLCQFYHSEAELQGDLDAVMETVEAYVRHLGKAYLDE
                     MGPAIAEVAGDTAHIERLLSLKAFPRVTFSEAVDLLGDTPDLVTEVADGARALTRKAEA
                     ALMDKFGEFVWVTHFDHLSVPFYQAYEPGDTSRARNGDLLFGIGETVGAGERHATAEQV
                     REALAHHEVAEEDYAWYLRMRELRPMQTSGFGLGVERFFLWLLRHDDIRDLQMLQRVNG
                     RQINP"
     gene            complement(6531..6701)
                     /locus_tag="H9W91_RS02180"
                     /old_locus_tag="H9W91_02175"
     CDS             complement(6531..6701)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H9W91_RS02180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H9W91_02175"
                     /product="hypothetical protein"
                     /protein_id="WP_162933607.1"
                     /transl_table=11
                     /translation="MAPRLAVLLTACAAAAATVLPVVSAHEGPAAGQATVTSAAPAPDV
                     ADATPLTWAWD"
     gene            complement(6995..7288)
                     /locus_tag="H9W91_RS02185"
                     /old_locus_tag="H9W91_02180"
     CDS             complement(6995..7288)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="H9W91_RS02185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="H9W91_02180"
                     /product="hypothetical protein"
                     /protein_id="WP_136240025.1"
                     /transl_table=11
                     /translation="MSLRQVAVETARVPGCAVEHVYEAVLPHRSRVGVLFVTAASPEAA
                     GYGVLLAVRGLLRRTEDHDQVLLRAPGPSEPALCHGIVTMPADAPLREMPVG"
     gene            complement(7430..8332)
                     /locus_tag="H9W91_RS02190"
                     /old_locus_tag="H9W91_02185"
     CDS             complement(7430..8332)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004939063.1"
                     /locus_tag="H9W91_RS02190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02185"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_237283483.1"
                     /transl_table=11
                     /translation="MSRELGVSEKEIRDCLDKLADLSMLSLPTGDDVLPVPVHPEVGLA
                     AHIHRREAEIEAQQRELAVARAAAADLAAAYAASQAGRGGRLETLSGMAEVRMRLTELS
                     RHAREELLAFMPGGALSQAALDASRPLDEQSLASGVRLRTVYLDSVRNDRATIEYARWL
                     STLGGQVRTSPMLPLRMLVVDRACAVLPLDPEESSLGAVVVRAPGVVAALVALFETLWE
                     QSAPLDGRALAGGDVEAPTPQESALLSLLAQGHTDEVAARKLGLSLRTVRRMMAVLTAR
                     LGARSRFEAGMLAARVGWI"
     misc_feature    complement(8640..8654)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.19"
                     /tool="antismash"
     gene            complement(8766..10004)
                     /locus_tag="H9W91_RS02195"
                     /old_locus_tag="H9W91_02190"
     CDS             complement(8766..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377493.1"
                     /locus_tag="H9W91_RS02195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02190"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_076689774.1"
                     /transl_table=11
                     /translation="MTAKRRPRSVTSDRELRLWRVGRALTLAFVAAILVAGGVFYGLVV
                     LLDFQEIDSTTKLDAKTLFDLVKLSFGVVAGAGALVALVVAYRRQRVDEAGAHRDATRL
                     HTERFSQAVDRLGSDSPAVRLGGVHALAGLADDAPDDNLRQTCIDVLCAYLQLPFTPDP
                     GSTEPAHQDEHHRYLALRKVRHTILGLIADHYRRPRGTHRSWQGCDLDLTGVTIDCDMD
                     FSDAVFSGGAVNLGRAVFSGGVVSFTRAKFCGGAVYFGDAEFSGGSVHFSGAVFSGGTV
                     HFGDAVFSGGAVYFSGAVFSGGTVHFGDAAFSGSSVHFSDAVFSGGAVHFGDAVFSAGT
                     VNFRGAIFSGATVNFRDTVFSSGAVYFSGAVFSGGAVYFTRATGPAPNGLATAVGTPAP
                     ATVVLASVWLPGG"
     gene            complement(10001..10846)
                     /locus_tag="H9W91_RS02200"
                     /old_locus_tag="H9W91_02195"
     CDS             complement(10001..10846)
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="H9W91_RS02200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02195"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_211824948.1"
                     /sec_met_domain="CDPS (E-value: 3.1e-70, bitscore: 235.0,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVTMAGEVAARVSALPFGASSERLVRRGDHALFGVSTGNSYFS
                     CRRLAEAVAWAVERFAVVDVVHADVALQATLEAFGYEPAAARRSATKQLRGVRRRIDGA
                     LKHVGASAERVRSRPLSDFLDQPGYQEVRARARAALRDDLEMRSVRDDTAFRFLAERLR
                     PDGLPAPAQVQAALAYVDAELPFFLDTPRILGVASSVHCYHSVLPLGRLLFGGRPKGPH
                     DAGPHHRQLPGSAARSGGAPAGSATSARAPPAPTRRGRGRVKWTGRRATMRRRARSSPS
                     "
     misc_feature    complement(10890..10904)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.95"
                     /tool="antismash"
     misc_feature    11046..11064
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.9"
                     /tool="antismash"
     misc_feature    11060..11071
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.54"
                     /tool="antismash"
     misc_feature    complement(11102..11119)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
     gene            11169..12542
                     /locus_tag="H9W91_RS02205"
                     /old_locus_tag="H9W91_02200"
     CDS             11169..12542
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038407.1"
                     /locus_tag="H9W91_RS02205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02200"
                     /product="MFS transporter"
                     /protein_id="WP_076687954.1"
                     /transl_table=11
                     /translation="MPRSTEIAPPASPPRPGHVPPRPERRAWLVLVMIVVFMMISYADK
                     AVLGLAAVPLMEELGIGKSTYGLISSSFYLLFSLSGLVVGFSSGRISSRALLLAMAALW
                     AVAQLPVLLVAAVPSLIAGRVLLGMAEGPAASMSMHALYKWFPTGRRGLPSALQIGGAA
                     LGTAVSAPLLTWLIVDHGWRSAFVALTLVSAAWCLVWPFVGQDGPFGEERKPVRGASRP
                     PRAAGPPLRALLTNGTVTGGILSAFGSHWALALSSAWLPVYLQTQMDMTATGASSVVSG
                     VSVVSLALLLSVPAYVDRLKRRGVSSRRADGIPQGMAVLVAGGALALLPFAAGGPVQLL
                     LIAVAFGCHAVALPLHYVTTATVVPDGRRGAVFGVVAASGTLPGLFVPYLTGHLVDGAA
                     TEATGYTAAFLLSAGVMAVCGLLAIATIHPERDARRLNPAGASVPAPRQAGVSKPVAQ"
     gene            complement(12509..13105)
                     /locus_tag="H9W91_RS02210"
                     /old_locus_tag="H9W91_02205"
     CDS             complement(12509..13105)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387902.1"
                     /locus_tag="H9W91_RS02210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02205"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_076687952.1"
                     /transl_table=11
                     /translation="MAEDRRVRKTRKALRDALVELVIERGFTALSVEDITQRADVGRAT
                     FYSHFRDKDELFARVTADLLAELDDRLRPVVQDSAVGFTGKPILQMLRHARDERDLYRI
                     VLRGEGDGKPLRMFTDACARVAAQEFRGRSERNAVEPRIDPELLARAWVGEQVAVLQWW
                     VEQDAPPMPAEEVVRMLLDLALRGRYWATGFDTPA"
     misc_feature    complement(13071..13087)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     gene            13238..14893
                     /locus_tag="H9W91_RS02215"
                     /old_locus_tag="H9W91_02210"
     CDS             13238..14893
                     /NRPS_PKS="Domain: AMP-binding (7-448). E-value: 3.4e-96.
                     Score: 314.3. Matches aSDomain:
                     nrpspksdomains_H9W91_RS02215_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387884.1"
                     /locus_tag="H9W91_RS02215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02210"
                     /product="AMP-binding protein"
                     /protein_id="WP_076687950.1"
                     /sec_met_domain="AMP-binding (E-value: 4.4e-102, bitscore:
                     340.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLGTYLTRSARHWPAHPALVCGDQTWSYDRLETAANRLASALRR
                     RGLRPGEAVASLAWNRAELVEVEFALYKAGLIRVPVNARLGRAEIEHILRDAPVRVLVF
                     DAAHREDALAAVEAARTDCLPVLLDTLVDEAPAAGGPVKGGAAVEGGVVDTGPADAGPG
                     AGPRPVPYADLLAEGDDGVVAVETAEHDPAVLNFTSGSTGALKAAVQTFGNRLANMRKT
                     LMSEDSRPGPHTRYLACGPITHATGMVLLAGVFGGATTHILPTWSAEAFFDTVERERIT
                     ATFLVPAMLNMVLAHPGAAERDLSSLTSVRVGGAPVSPQRLRDAVALFGPVVAQGYGLA
                     ETTSVVAGLSSADVLRGVTEDEELLRSCGRPAYDSEVRVVDERGGELPPREIGEVIVRG
                     PDCVSEYWHAPDLSAETFRDGWVHTGDLAFMREDGYLFLVDRKKDMIISGGFNIYSTEV
                     ETALYEHPAVQEACVIGVPDEKWGEAVKAVVVTRPGQHVGERELADFCALRLDRFKKPR
                     SVEFVTALPHNRNGKLDRKAVREPYWAGADRRVH"
     aSDomain        13259..14581
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_H9W91_RS02215_AMP-binding.1"
                     /evalue="3.40E-96"
                     /label="H9W91_RS02215_AMP-binding.1"
                     /locus_tag="H9W91_RS02215"
                     /protein_end="448"
                     /protein_start="7"
                     /score="314.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="TRSARHWPAHPALVCGDQTWSYDRLETAANRLASALRRRGLRPGE
                     AVASLAWNRAELVEVEFALYKAGLIRVPVNARLGRAEIEHILRDAPVRVLVFDAAHRED
                     ALAAVEAARTDCLPVLLDTLVDEAPAAGGPVKGGAAVEGGVVDTGPADAGPGAGPRPVP
                     YADLLAEGDDGVVAVETAEHDPAVLNFTSGSTGALKAAVQTFGNRLANMRKTLMSEDSR
                     PGPHTRYLACGPITHATGMVLLAGVFGGATTHILPTWSAEAFFDTVERERITATFLVPA
                     MLNMVLAHPGAAERDLSSLTSVRVGGAPVSPQRLRDAVALFGPVVAQGYGLAETTSVVA
                     GLSSADVLRGVTEDEELLRSCGRPAYDSEVRVVDERGGELPPREIGEVIVRGPDCVSEY
                     WHAPDLSAETFRDGWVHTGDLAFMREDGYLFLVDRKKDMIIS"
     CDS_motif       14399..14488
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_H9W91_RS02215_0001"
                     /evalue="9.00E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="H9W91_RS02215"
                     /protein_end="417"
                     /protein_start="387"
                     /score="14.9"
                     /tool="antismash"
                     /translation="PPREIGEVIVRGPDCVSEYWHAPDLSAETF"
     gene            14931..16109
                     /locus_tag="H9W91_RS36695"
                     /old_locus_tag="H9W91_02215"
     CDS             14931..16109
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330269.1"
                     /locus_tag="H9W91_RS36695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02215"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_211824950.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.1e-15, bitscore:
                     56.0, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.9e-18, bitscore:
                     65.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.7e-40, bitscore:
                     135.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFSFRPTYDDPQLAGLVDRLRTYLDGELAGYERERGITHETRLT
                     RADLEPVWRRSRELGFYGIHLPEEYGGQALSNVRLAALKEEIGACGRVLGHSVLGDMGG
                     PLRAGDILKYATEHQLTTYLLPLVRGERACCFSLTEADAGSDVRSMTTTATPDGDGYRL
                     TGHKVFSSAGPFADFAIVVARTAGTENSFSAFLVDLDSPGCRVAEGATPMSGEHIESDI
                     ILEDCHVPAANLLGEQGQGLKIALGRVTNNRLLHCPTAIGAARRALHLTRDRALTRKAA
                     GGRLLMEMQSIQHKLADMATELYAARSMTYAALAALDGGSDVRAEAFMCKLFVAESAFR
                     ILDQAVQIHGKDGLTQGNEIEYLFRKMRMFRVLTGTSEIQRNGIAKSLVTLA"
     gene            16150..18048
                     /locus_tag="H9W91_RS02225"
                     /old_locus_tag="H9W91_02220"
     CDS             16150..18048
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330268.1"
                     /locus_tag="H9W91_RS02225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02220"
                     /product="alkyl sulfatase dimerization domain-containing
                     protein"
                     /protein_id="WP_211824952.1"
                     /transl_table=11
                     /translation="MTHTSQDHDSPADGPDDAEDFADAARGFIARLEPGAVHDATGRLV
                     WDADAYAFLEEDCPPTAHPSLWRQSRLVARQGLFEVVPGVYQVRGLDLSNITFIEGRHG
                     VIVVDPLISTEVAAAALSLYRTHRGERPVTGVVYTHCHVDHFGGVRGIIDPAEAASGRV
                     PVIAPAGFLEHAAGENVMTGPAMGRRSGYMYGAALPKGPAGQIGCGLGQTTSLGGISLI
                     APTLDVTATGQTETVDGVRLVFQLTPGTEAPAEMNFHLPDLRVLCVAENACHTLHNVLT
                     LRGALVRDPSAWARYLTETLALFADDTDVVFASHHWPTWGQDRAVRFLEEQRDAYAYLH
                     DQCVRLINAGRTGAEIAEELRYPPALERAWHVRGYYGSLSHNAKAVYQRYMGWFDGNPA
                     HLWQHPPREGAERYVAFMGGADAVVDKARASFEAGDLRWTAEVLSHVLLARPEHAAARA
                     LQASAFEQLGHGAECGPWRNFYLMGAMELREGVRGTPSRGAPDIIAALTVEQIFRSMAV
                     RINGPRAAAAGRILLRWEITAPEPAPGSPGTAETWTVLLSNGALTPMRGGAPRGEDPDV
                     TLRLPRTVLDAVMSRATTFADAIARGDATVEGDVRTLLTFGSLTDRPDTRFPIVTR"
     gene            complement(18056..19294)
                     /locus_tag="H9W91_RS02230"
                     /old_locus_tag="H9W91_02225"
     CDS             complement(18056..19294)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487627.1"
                     /locus_tag="H9W91_RS02230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02225"
                     /product="aromatic acid exporter family protein"
                     /protein_id="WP_076689772.1"
                     /transl_table=11
                     /translation="MPDVSAPVIKLVRRTTEPVAAQTLRSTAAAVISFGVALMVLPPRP
                     APLTAPLTALLVVQVTLYATLTTGIRRVNAVVVGVLIAIGFTTLVGLTWWSLGLTIFTS
                     LIIGRFVRVNEFVPEVAISAMLVLGVSQATSAAWHRVLETLIGAGVGLLFNLLFAPPVW
                     TQSAGASIDGLARAMGRMFRTMGAEIAEGPIPFPRAAARLHEARRLDHDIVEVDASLRQ
                     AEESLRMNPRVREGLLSRVVLRTGLDTLEICAVVLRVLTRSLTDLAKFRRREALFPPDV
                     SAGLHELFEQMAEAIENFARLITSQVTANAEQAEERLTATLAASRITRDRVAEMLLRDV
                     QEYPRQWQLHGALLAEIDRILDELDLDKRTERLMQELDRHSAELSERHPRLAALRRRLR
                     GQSGTERRPVVEA"
     gene            complement(19377..19952)
                     /locus_tag="H9W91_RS02235"
                     /old_locus_tag="H9W91_02230"
     CDS             complement(19377..19952)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007504155.1"
                     /locus_tag="H9W91_RS02235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02230"
                     /product="ATP-binding protein"
                     /protein_id="WP_076687943.1"
                     /transl_table=11
                     /translation="MIVWLNGTHGAGKTTTGALVRQLIPDSRVFDAEKVGETLMDITPG
                     LPWTGNFQDWPPWRPLVVETARHVLDYTGGTLVIPMTVLVEQYWREISSGLAQHAIPVR
                     HFVLHADQDTLRGRIAGDTVLGPDSPFRLQYLEPYAEAAATWLHAEAEVVDTTHLTPGQ
                     TAQRIAEAVQNRANGPSGGPPDQGVGST"
     gene            complement(20019..20611)
                     /locus_tag="H9W91_RS02240"
                     /old_locus_tag="H9W91_02235"
                     /pseudo=""
     CDS             complement(20019..20611)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019548573.1"
                     /locus_tag="H9W91_RS02240"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="H9W91_02235"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRGVATGTGDRSRPRAALPALCATHIVSRGIAYCAFPVRNPRITT
                     ATGRPAGATTAAFSLGLAVSARAGIRVRRTLDRRGPRAVMTTGPSSGRSVRSSPWRSWP
                     ARSGATSPSSRPPPSPTAGAPPTMAASPDSSRHRPRPPRPSRRSPASPWPSPSAATAPS
                     SSSSPPSRWPPYSSSPGRFRLTDPADASVLTAAG"
ORIGIN
        1 ggtgacgtac cagctctgtg tcgcctcgtc ccaccacacg gggtcggtcg tgcgcaggtg
       61 ggtgtagtgc gggtgcgggt cccgggcgaa ggactccgac agcaggtcga cggccatggt
      121 ggtgtgctcc ctgtcgcggt caggcggggc ggcgggcgac gacgaagagg ttgttgccgc
      181 gtcccgcgat gccgggcgcc ttgcggaccc gcttctccat ggcgaggacg cgctcgaagt
      241 cgtcgccggc caggatgtcc acgagctgtt cggtggagcc gtggagctgg gtctcctggt
      301 agccggggta gatgaggttg gggaagccgg agagcgcgtc gatctccagt ccggccgcgg
      361 cgtgcatctc ctcgatgcgc tgcacgtcgt acaggtgcat gtcgggcatg gtgtcggtga
      421 accggccccg gcgggtcagc gccttctcgg cctcgtcgat gttgccgacg gcgatgttga
      481 accacgcggt gtgccagacg ctgggcagga acgacaccag caggccgccg ggcttgagca
      541 gtcctgcgac gtccttgatg gtctgctcgg ggtccgccac gaagccgagg acgttgtgga
      601 agttgaacgc caggtcgaag gactccccgc gcagcgtctc ccccacgtcg gccaggtcgc
      661 cctggacgaa gcggacgcgg tcggcgaagc cgcgttcggc ggccttcgcc tccgcgacct
      721 tgatcatttc ccgggtgagg tcgaagagga cgcccgtgct ccggggggcc tcctgggcga
      781 agaaggacgt ccagcggccg gtgccgccgc cggcgtcgag gaaggcgaag tcctccggca
      841 gggcgctgat gacgtcctcg cggagggcgt cggcgagcag gcggtcggag aggacccagt
      901 agggctggag gtcgacgtcg tcgtaggcct cggccttgtc ggcgaagtag ccgcggactt
      961 ccttctcgta cgtgggctca gtcatgttcg tctcttcctc gtctgcggtt cggaaaacgg
     1021 tgagtggtga aggctgagtg gtaagcggtg cgcgggttgg aggggtggtc aggcgtcggt
     1081 cggttcggtg cggaagctgc tgttgagggc cttctccagc tcccggccac gctcctcgaa
     1141 ctgctccagg gagtcggccc cgtagatgag gtgcaggcac cacgcggagg ggtgggggtc
     1201 ggagaagtcg tcgcccacgc cgtgcgggcg caccgtctcc aggacgtagt cgaacgcgtc
     1261 gatctcggcc tgggtgggct cggcggtgat ccggccggcc tcggacggcg ccaggttgat
     1321 ccagcccacg taccggctgg gctcgccgtc cgcgtagggc gccgggcggc cggggtcgac
     1381 caccgacttg atccaggcga tgcgcaggtc gtcgccgagc gcgcggtagg tcgcggtgat
     1441 gccgccgccc gcgaaccggg aggcgatctc ggagaacacc acctcgcgct cccccggctg
     1501 cttgaagaac tccaggtggg tgatgccctc gcggatgccg agggcgtcgt tgacgcggcg
     1561 gtgggcctcc tcgacgtccg cgtacagttc ggcccactcc tcgcgcggca gcagcacgga
     1621 gccgttgctc tcgccggccg tctcgatggc cagccgcggc cgcaggtagc gcatgatgcc
     1681 caggaccttg ctgcggccgt ccacccagat cgcgtcgacg tggaactcgt cgccggacac
     1741 gggccgttcg gccatcagga agtgctcggt gttgtcgccc ccgaggtcgg tgaggagctt
     1801 ggtcagctcc tcctctgagt gcacccagct cgtgcccagg gtgcccaggc ccgcgcaggg
     1861 cttgaccacc gcggggaagc cgatctcctc ggcggtgcgg cgcacgctcg cggccacctc
     1921 ggaggtgcgc agcgacacga agtccgtgca ggtgaccccg gcggcgcgca ccgcctgctt
     1981 catggcccgc ttgtcgcggg tgttgagggc catctccagg gtgggctggg cgcagccgag
     2041 gagctgggcg aggtagccgg cgccgtactg gctgaactcc gagaggctca ccacccggtc
     2101 ggggagccag ccgtcgttct tgagctgggt ggcgacctgg ccgagttcgt ccatgtcgtc
     2161 gaagctgttg atgcggaaga cgtatggcag ggtcttcagc acctcctcgt cgacgtggaa
     2221 gtgggcggcc tcgaaggtgt cgaagaggag ggcgacctcg gctccctccg cgcgcagcgc
     2281 ttcgaggatg taggggtccc agcggcagac gagaacacgg gtggacatgg caggggtctc
     2341 cttcgggtgg gtgcgggtgg tacggggcct gcggcagccg tcaggcccgg gcgtcttcct
     2401 ctgcggcgtc ctcgtggccg gtcctctcca ggccggacag gggtgtcctc ggcaggaacc
     2461 gggaacggac cgtgatcagc gccaggaccg cgaggacggc cgtgaagccg agcatcatcg
     2521 acgtggtgtg gccgtcgtcg gtcaggcgcc ccgagacgag cgggccgacc gtgaagccga
     2581 gtgaacagac gaagccgtag gcggcgttga agcgcccccg gttggagtcg tcggcccagc
     2641 tgttgaccag ggtgggcccg gtcgcggcca gcagggactc ccccaccgcg aagacgacca
     2701 tggcgatgac gccgacgagc agggcgacca ggccgccgct gaggccggtg accgcccaga
     2761 tcagcagcca gaaggcggcc cagctggcgg cgagcagcgc gagggccaca cccgcggtga
     2821 cctgcttgat ccggccgatc agtgccgcct ggaccaggac gacggccgcg gtgttggcgg
     2881 cgaagagcac accgagctcg gtggggccga ggcggctgtc ggccaagagg gcggcgggca
     2941 tgccggagtt gagctgggag tagccgacgg tgaacaggac cagcaccacg accagcaggg
     3001 cgaccagcca gcggtgcccc agcaccgcac ggtagctgct gcggggctgg tcggccgccg
     3061 cggcctccgg cggggtctcc ccggtgggcg gctccaccga ccggcgccgg cggacctccc
     3121 gggcgaccag ccagccggtg acgaggaagg acgccgcgtc gagcaggaag agtgcctgga
     3181 agacggcgag cgagtccgtc atgcccgcca ggaggccgcc gagcagtccg ccgatgccca
     3241 tcatcgcgtt gaccatggcg aagtcggcgg agaagagcac gggccagtgc tcctcgggca
     3301 ccagatcggc catgagcgcg ttccaggtga tggccccgcc cacgccgagt ccctgcacga
     3361 atccggccgc cagcgccgtc gtgggggtgt cgcacagcgc gtagccgacg gctcccaggg
     3421 cggcgcacac cagcgcggcc cagacggcgg gcacccgccc gaggcggtcg gagacccacc
     3481 ccgcgagcgg gccgccgacc agtgcgccca ccgaggtggc ggcgaccgcg ccggtggccg
     3541 cggtcaggga gaggccgcgc atctcgtgca ggtagatgac caggaggggc agtacgacgc
     3601 cgctgccggc cgcgttgacc gcgttgagca cgatcaggcg tctggcacgg ggcgggagct
     3661 gccgcagcgt ccgcagactg ttcatggggg gtcgagtcct gtcaggtgtg gaagagcggg
     3721 cggtcactga ggacgtccgc gcgggggtac agggcgaccc cgtagcgcga caggacgtcc
     3781 agttgctttc ggatctgcgg gaccgcggcg gcggggtcgc tgtggtcgcg cggcgtcatg
     3841 ccgatgcgct cgaccgcctt ctcgaccgcg atgttctccc agcgtccgag ctggggcatc
     3901 agcagatgct ggtagtcggc ctgccagagg cgcagcacgg cccggtcgtt gacctggcgg
     3961 acctggtcca gggtggtgtg gttgagccgc cgggcggtgt gcacgtccat gccgatgtgg
     4021 gaccacgagt agtccgggtc gtcggggtcg tgcacctcga tgcgcagggc ctccttgtcc
     4081 tcccacagcg gcatcgtctc gtcggagatg ctgaagacgc tgagcatgaa gtgccccgcg
     4141 tactcctccg agaggaagtc ccgtgtctcc gcgaagtcct cgggccgctc ccccgggtag
     4201 ccggccatga acgagcagcg gtagccgagc ccgccctcgt tcagcagccg gaaggcccgc
     4261 aggttgtcct tccgtgtgac cttcttgttc atgtaccgca gcgtgctgtc actcatcgac
     4321 tcgaagccga tggacaggaa ctggcagtgg gaggccgcca gttgagcgat cagttccggc
     4381 gtcttgagga cgttggcccg gctgtagccc tcccagccca ccccgacgtc gggcagcagc
     4441 cgcatcagct cccgcagccg ggtcggcggc acggtgaagg tgctgtccat ggccgagatg
     4501 taggaggccc cgttctcgtc cgcgtagcgc cgccagtcgt cggcgatctt ctgggcggac
     4561 ttgtagcgcc acttggggct cgcggcaggg aacgagcaga acttgcagct gaacgggcag
     4621 ccgcgcatcg actcgtacgg aatgacgcgc cactggcctt tcggcgaggg cgaggggaag
     4681 gcgtccaggt ccaggtactc gaaggggctc atccggtagc cgagcagttc ccgggagtgc
     4741 cggtagacca ggttcggcac cgtctcgggg tcactgccct tctccagtgc ggtgagcagc
     4801 cccggcaggg cctcctcccc gtcaccgcgc acgatgtagt cgatctccgg tatcgaccgc
     4861 atcagcgagg tgtacttgag gttgctgtac tggccgccga gcacgatcgg gataccgggg
     4921 taggtcgcgg agatccactg gacggcgtgg cgcaggtcgc ggtcggtcca gatgaagctc
     4981 gtggacagca gcgccgcccg gtagtcgccc tggggcgccg gggcgggcag gtcgtccgtc
     5041 cacagattgg tggcgtcgta ggtgtcgacg tggtggccgg cccgttccag gatctcctgg
     5101 acggcgaagg tggtgaggtg cgggacgttg tagtagcggg gtctcagcag cgggtagtcc
     5161 gtgccgttgt gccggaagcc taggcgccgc agcccgaagt cctccaggtc cgtgcccttg
     5221 aggtaggccg ccgtgttcgc gtcgccgctc tggcggtcca gcatggtggt ggcgaggtag
     5281 tccgagttct tcagtgtcgg cccgagtcct gacacaagta cgacgtcgat ggtgcactct
     5341 cctgggtggg cacggagcgg cggggacttg tcgggggttc aggggttgat ctggcggccg
     5401 ttcacccgct ggagcatctg gaggtcccgg atgtcgtcgt gcctgagcag ccacaggaag
     5461 aaccgctcga cgccgaggcc gaacccggag gtctgcatcg gccgcagctc ccgcatgcgc
     5521 aggtaccagg cgtagtcctc ctcggcgacc tcgtggtggg ccagcgcctc gcgcacctgc
     5581 tcggcggtgg cgtgccgctc gccggcgccg accgtctcgc ctatcccgaa cagcaggtcg
     5641 ccgttgcggg cgcgggacgt gtcacccggc tcgtaggcct ggtagaaggg cacggagagg
     5701 tggtcgaagt gggtcaccca gacgaactcg ccgaacttgt ccatcagcgc ggcctcggcc
     5761 ttgcgggtga gggccctggc gccgtcggcc acctcggtga cgaggtcggg ggtgtcgccg
     5821 agcaggtcga ccgcctcact gaaggtgacc cgggggaagg ccttcaggga cagcagccgc
     5881 tcgatgtgcg cggtgtcccc cgcgacctcg gcgatggccg gtcccatctc gtccaggtag
     5941 gccttcccga ggtggcgtac gtacgcctcc acggtctcca tcaccgcgtc caggtcgccc
     6001 tggagctcgg cctccgagtg gtagaactgg cagaggtggg tggggtcggg cgcctcgccg
     6061 cggaacgagg gcatcacgta gtacgagccc ttctcccaca tgcggcagct gtactccagc
     6121 aggaactgca tggagtcggc gaggtaggtc ggcacgccct ccaggtcgat gcgcaccggc
     6181 accgagtcgc tgcccaggcc catggggctg gagatcgacc ccgtggtcac cggcaggtag
     6241 gcggcgcgga cgtcacgtcc cgcccagaac tccacggtgg cccgctgcat gacgtccgtc
     6301 agccggagca gcaaccggta ccaggggtgt gtcagggcca cctcgaagtg ctcgtcggga
     6361 gtgcgccacg tgcccggtgc ggtaagcggc tgcgtctggg tcatgtacgt gctcacgtgt
     6421 cctcctcgga ccatcggtgc ggggttggtg cgatgtgggc cggccgcggg gatccgggcg
     6481 gctgtgcctc gctcattcgg cggcgcggca cgctgcggca ccggggccgg tcagtcccag
     6541 gcccaggtga ggggcgtggc gtcggccacg tcgggggccg gtgccgcaga ggtcacggtg
     6601 gcctggccgg ccgccgggcc ctcgtgggcg gagaccacgg ggaggaccgt cgcggcagcg
     6661 gcggcgcagg cggtcagcag gacggcgagt ctgggtgcca tgtggctcat ctcctgacgg
     6721 tcgtgcgaaa gaacctgctg gtcacagcgg ttcctgtcgg tgcgaacagt tttcggcccc
     6781 gctacccgcc gggcaaggga tgcggatggc agcaaggtgc gttggcacca aagggccctg
     6841 tggggggtgc ggttgcggat ggcaggtgag cgggcatgcg aaagccgccg accacgggcg
     6901 gcggcaacgg gccgcggcca cagggcagtc gacgggcagt cagcggttct tcaccgcagg
     6961 gtgcggcccg cggagcgggg cacactcgcg aggtctaacc gacaggcatc tcccggagag
     7021 gggcgtccgc gggcatggtg acgatgccgt ggcacagggc gggctcgctc gggccgggcg
     7081 cgcgcagcag cacctgatcg tggtcctccg tgcggcgcaa caggccgcgc acggccagga
     7141 gcacgccgta ccccgcggcc tccggggagg ccgcggtcac gaagagcacg cccacgcggc
     7201 tccggtgggg cagcacggcc tcatagacgt gctccaccgc gcagcccggc acacgagccg
     7261 tctccacggc gacttgacgc aggctcaccg cggccgtcgc ggacgactgc ggtgacactt
     7321 ctacatgaat ggcgtacacg gccaccgacc attccagtcc agcctcgccg ccgggcggtc
     7381 cagcggtgac agcttatggc cgtggcagca agaggaccgc cgcccgggct cagatccagc
     7441 cgactcgcgc ggcgagcatc cccgcctcga agcggctccg ggccccgagc cgggcggtga
     7501 ggaccgccat catccgccgt acggtacgca gcgacaggcc cagcttccgc gccgccacct
     7561 catcggtgtg accctgcgcg agcagactca gcagggcgct ctcctgcggg gtgggcgcct
     7621 cgacgtcccc gcccgccagc gcccgcccgt ccagcggcgc gctctgctcc cacagggtct
     7681 cgaagagggc caccagggcc gccaccacgc cgggcgcccg caccacgacg gcgcccaagg
     7741 aggactcctc cgggtcgagc ggcaggacag cgcaggcgcg gtccaccacg agcatccgca
     7801 gcggcagcat cggactggtc cgcacctgtc cgccgagggt ggacagccag cgcgcgtact
     7861 cgatcgtggc gcggtcgttg cggacactgt ccaggtagac cgtccgcagc cgcacgccgg
     7921 aggcgaggct ctgctcgtcc agtggccggc tggcgtccag cgcggcctgg ctcagggccc
     7981 cgcccggcat gaaggcgagc agttcctcgc gcgcgtgccg gctgagttcg gtgagccgca
     8041 tccgcacctc ggccatgccg ctcagcgtct ccaggcgtcc gccgcgccct gcctggctcg
     8101 cggcataggc ggcggccaga tcggccgcgg ccgcgcgcgc cacggccagc tcgcgctgct
     8161 gcgcctcgat ctcggcctcg cgccggtgga tatgggcggc gagcccgacc tccgggtgca
     8221 cgggcaccgg gagcacgtcg tcgcccgtgg gcagcgacag catggaaagg tccgcgagct
     8281 tgtcgaggca gtcgcggatc tccttttcgg agacccccaa ttcccgggac aagtcgtcga
     8341 cggtccgctg cggccctgag acgacgagac ggaaaacggc cacacacagg tcgtcctgcc
     8401 cgatcaacgt cgcgagcgaa ctgtcccctt caggtgcgag ctgttccgat atgggcgcaa
     8461 gtgggcgcac cttactacct gtctgcatgt tcccccgatt cacgcatcgg ccacaccgat
     8521 gtcggccaaa atacccgggg tcgcttctca ccgccatgaa ctggcgtgat cactcccccg
     8581 gagcaaggca ttcctcccga caggtggtat acgcctgtgc caccgcttct gtcgagacct
     8641 ggccgaatcg atcagggcga tccgtgccga tccgggccac tctgggccga tccggcggag
     8701 ccgggccgcg acaccggccg tcgccggagc gaagcggacg gaacgactgc cctccgtccc
     8761 cctccctagc cgccggggag ccagacggag gcaaggacga ccgtcgcggg agcgggcgtc
     8821 ccgacggcgg tggcgagccc gttgggggcc gggcccgtcg ccctggtgaa atagaccgcg
     8881 cctccggaga acaccgctcc gctgaagtag accgcgccgc tggagaacac ggtgtcccgg
     8941 aagttcaccg tggccccgga gaagattgct ccgcggaagt tcaccgtgcc ggcggagaac
     9001 accgcgtccc cgaagtgcac ggctcctccg gagaacaccg cgtcactgaa atggaccgag
     9061 ctgccggaga aggccgcgtc gccgaagtgg accgtgccgc cggaaaatac cgccccgctg
     9121 aaatacaccg cgccacccga gaacaccgcg tcgccgaagt ggaccgtacc gccggaaaac
     9181 accgccccgc tgaagtggac cgagcctccg gagaactccg cgtcgccgaa gtacacggcg
     9241 ccgccgcaga acttcgcccg ggtgaaggac accacgcccc cggagaacac cgcccggccg
     9301 aggttcacgg cgccgccgga gaagacggcg tcgctgaagt ccatgtcgca gtcgatggtg
     9361 acgccggtga ggtcgaggtc gcagccctgc caggagcggt gggtcccccg cgggcgtcgg
     9421 tagtggtcgg cgatgaggcc gaggatcgtg tgccggacct tgcgaagggc caggtagcgg
     9481 tggtgttcgt cctggtgggc cggttcggtg ctaccggggt cgggagtgaa gggcagctgg
     9541 agataggcgc acaggacatc gatgcacgtc tggcgcagat tgtcgtcggg ggcgtcgtcg
     9601 gccagcccgg ccagggcgtg gactccgccg agccgcaccg cgggcgagtc ggagccgagt
     9661 ctgtcgacgg cttgggagaa gcgttcggtg tgaagccggg tggcgtcccg gtgcgcgccc
     9721 gcctcgtcga cgcgctggcg gcggtaggcg acgaccaggg cgacgagcgc gccggccccc
     9781 gcgaccactc cgaaggagag tttcaccagg tcgaagagcg tcttggcatc aagtttcgtg
     9841 gtggagtcga tctcttggaa gtcgagcagc accaccagtc cgtagaagac gccgcccgcg
     9901 accaggatcg cggcgacgaa ggcgagggtc agcgcccggc cgacccgcca cagccgcaac
     9961 tcccgatcac tcgtgacgga acgcggcctt cgcttggctg tcatgacggt gaggaccggg
    10021 cgcggcggcg catggttgca cgccggccgg tccacttgac ccgcccccgg ccccgtcggg
    10081 tgggcgcagg aggtgcgcgg gcgctcgtgg cggagcccgc gggcgcgccg ccggaccggg
    10141 cggcacttcc cgggagttga cggtgatgtg gaccggcgtc atggggtccc ttcggccgcc
    10201 cgccgaacaa caggcggccc agcgggagga cggagtgata gcagtggacg gacgaggcga
    10261 cgcccaggat ccgtggggtg tcgaggaaga acggcagctc ggcgtccacg taggccagtg
    10321 ccgcctgcac ctgggcggga gcgggcaggc cgtcggggcg cagccgctcg gcgaggaacc
    10381 ggaacgccgt gtcgtccctg accgaccgca tctccaggtc gtcgcggagt gccgcgcgtg
    10441 cccgcgcccg cacctcttgg tagccgggct ggtcgaggaa gtcggacagc ggcctggacc
    10501 gcacgcgctc cgccgacgca ccgacgtgct tgagggcgcc gtcgattcgc cgccgcacgc
    10561 cgcgcagttg cttcgtcgcg cttctgcgcg cggcggccgg ttcgtagccg aaggcttcga
    10621 gcgtcgcttg cagggccacg tcggcgtgca ccacgtccac gaccgcgaag cgctccaccg
    10681 cccaggcgac cgcctcggcc aaccggcggc aactgaagta gctgttgccc gtgctcacgc
    10741 cgaacagcgc gtggtctccc cgccggacga gacgttcact gctcgccccg aagggcaggg
    10801 cgctcaccct cgccgcgacc tcaccggcca tcgtgactct tcgcatcagg ctcttcgcgc
    10861 atgccgggca acgtacccac gtacagtgac gaacatgttg tccagtccct gaaggcgtga
    10921 cgctgagtag ttctcagcag gactgtgtcc cagcgcgcgc ctcacgctcc gtcatccgcc
    10981 ctcgcgacac tgtcggggcc ccgcacaccc ttcggaaccg ggcgtcgcct cggcgttgcg
    11041 gcggcattgc gacggcgtcg aaaccgttga ccttccctgc cgagccgttt acgttgccga
    11101 accaacagca agttaacaga cagcttgttc agttacgcga ctacgcgtca cgcgccgcaa
    11161 ggagtcccgt gccacgctcc accgagatcg cgccccccgc atcgccgccc cgacccggcc
    11221 acgtgccacc ccgccccgaa cggcgggcat ggctggtcct cgtcatgatc gtggtcttca
    11281 tgatgatcag ttacgccgac aaggccgttc tcggtctcgc ggcggtgccg ctgatggagg
    11341 agctgggcat cggcaagagc acgtacgggc tgatctccag ctccttctac ctcctgttca
    11401 gtctgtccgg gctggtcgtc gggttctcct cgggacggat ctccagccgc gccctgctcc
    11461 tcgccatggc cgcgctctgg gccgtcgccc agctcccggt cctgctggtg gccgccgttc
    11521 cctcgctgat cgccgggcgc gtcctgctcg gcatggcgga gggccccgcg gcctccatgt
    11581 ccatgcacgc gctgtacaag tggttcccga ccgggcggcg gggcctgccg tccgcgctgc
    11641 agatcggcgg cgcggcgctc gggaccgccg tctccgcccc gctgctgacc tggctcatcg
    11701 tggaccacgg ctggcgttcg gctttcgtgg ccctcacact cgtcagtgcc gcgtggtgcc
    11761 tggtctggcc cttcgtggga caggacgggc cgttcggcga ggagcggaag ccggtccggg
    11821 gagcgagccg tccgccgcgc gcggcgggtc cgcctctgcg ggccctgctg acgaacggca
    11881 ccgtgacggg cggcatcctc agcgccttcg ggtcccactg ggcactggcc ctgtccagcg
    11941 cgtggctgcc ggtctacctg cagacgcaga tggacatgac cgcgaccggc gcctcgtccg
    12001 tcgtcagcgg ggtgtcggtg gtcagcctgg cactcctgct gtccgtgccc gcctatgtcg
    12061 accgtctcaa gcgccggggc gtgtccagca ggcgcgcgga cggcatcccg cagggcatgg
    12121 ctgtcctggt ggcgggcggc gcgctggccc tgctgccctt cgccgcgggc gggccggtcc
    12181 aactcctgct gatcgcggtg gccttcggct gccacgcggt cgccctcccg ctgcactacg
    12241 tcacgacggc gacggtcgtg ccggacggcc gccgtggcgc cgtcttcggc gtcgtggccg
    12301 cttcgggaac cctgccgggc ctcttcgtgc cgtacctgac cggtcacctc gtcgacggcg
    12361 cggccaccga ggcgaccggc tacaccgcgg cgttcctgct gtccgcgggc gtcatggccg
    12421 tgtgcgggct cctggcgatc gccaccatcc accccgagcg ggacgcccgg aggctgaatc
    12481 ccgccggggc gtccgtcccg gcgccccgtc aggcgggcgt gtcgaagccc gtggcccagt
    12541 agcggccgcg cagcgcgagg tcgagcagca tgcgcacgac ctcctcggcc ggcatggggg
    12601 gcgcgtcctg ctcgacccac cactgcagga ctgcgacctg ctcccccacc caggccctgg
    12661 cgagcagctc gggatcgatc ctcggttcga ccgcgttgcg ctcggagcgg ccacggaact
    12721 cctgcgcggc gacgcgggcg caggcgtccg tgaacatccg cagcggtttg ccgtccccct
    12781 caccgcgcag cacgatccgg tagaggtcac gctcgtcccg cgcgtggcgc agcatctgca
    12841 ggatgggttt gccggtgaag cccaccgcgc tgtcctgcac cacgggtcgg agccggtcgt
    12901 cgagttcggc caggaggtcc gcggtcaccc gggcgaagag ctcgtccttg tcgcggaagt
    12961 ggctgtagaa ggtcgcgcgg cccacgtcgg cccgctgggt gatgtcctcg acgctcaggg
    13021 cggtgaaccc ccgctcgatc acgagttcca ccagagcgtc acgcagcgct ttgcgtgtct
    13081 tgcggacgcg cctgtcctcg gccaacgccg tcccccattt ccttgccgtg cccgagcccc
    13141 tggagtgggg cgacagctca gtgtacggaa gccttgacag tcccaccgtt actgaacaaa
    13201 ctgtccggaa acttacagcc tgctctggag ccgcccgatg aacctcggca cgtacctcac
    13261 acgcagcgcc cgccactggc ccgcgcaccc cgcgctcgtc tgcggggacc agacctggtc
    13321 gtacgaccgg ctggagaccg cggccaaccg gctggcctcc gcgctgcggc ggcgggggct
    13381 gcgtcccggg gaagccgtgg cgtcactcgc gtggaaccgc gccgaactcg tggaagtcga
    13441 attcgccctg tacaaggcgg ggttgatacg ggttccggtc aacgccaggc tgggccgcgc
    13501 ggagatcgag cacatcctcc gggacgcacc cgtccgcgtc ctggtgttcg acgcggcgca
    13561 ccgggaggac gccctggccg ccgtcgaggc ggcccgtacg gattgcctgc ccgtactgct
    13621 cgacaccctg gtcgacgaag caccggccgc gggtggacca gtcaagggtg gagcagcagt
    13681 cgagggcgga gtggtcgaca cgggaccggc cgacgcggga ccgggcgcag gtccccggcc
    13741 ggtaccgtac gccgacctgc tggccgaggg cgatgacggc gtcgtcgccg tcgagaccgc
    13801 cgaacacgat ccggccgtcc tcaacttcac ctcgggttcg accggcgctc tcaaagcggc
    13861 ggtgcagacg ttcggcaacc gcctcgcgaa catgcgcaag accctgatga gcgaggattc
    13921 ccggcccggc cctcacaccc gttacctggc ctgcgggccc atcacccacg ccaccggaat
    13981 ggtgctgctg gccggtgtgt tcggtggcgc gacgacgcac atcctgccga cgtggagcgc
    14041 ggaggccttc ttcgacaccg tcgaacggga gcggatcacc gccacgttcc tcgtgccggc
    14101 catgctcaac atggtgctgg cccacccggg cgcggcggag cgcgatctgt cgagcctcac
    14161 gagcgtacgc gtcggcgggg ccccggtgtc gccccagcgg ctgcgcgacg ccgtcgccct
    14221 cttcgggccg gtggtggccc agggctacgg tctcgcggag accaccagcg tggtcgcggg
    14281 actctccagc gctgacgtcc tgcgaggggt gaccgaggac gaggaactcc tccggtcgtg
    14341 cgggcgcccc gcgtacgact ccgaggtccg tgtcgtcgac gagcgcggcg gcgaactgcc
    14401 gccacgtgag atcggggagg tcatcgtgcg cggtcccgac tgcgtgagcg agtactggca
    14461 cgctcccgat ctgtcggcgg agaccttccg cgacggctgg gtgcacaccg gtgacctggc
    14521 cttcatgcgt gaggacggct atctgttcct cgtcgaccgc aagaaggaca tgatcatctc
    14581 cggcggcttc aacatctaca gcaccgaggt cgagaccgcc ctgtacgagc accccgccgt
    14641 gcaggaggcc tgtgtgatcg gcgtgcccga cgagaagtgg ggcgaggcgg tcaaggccgt
    14701 cgtcgtgacc cgcccgggac agcacgtcgg cgagcgggaa ctggccgact tctgcgccct
    14761 gcgcctcgac cgcttcaaga agccccggtc ggtggagttc gtgaccgcgc tcccccacaa
    14821 ccgcaacggc aagctcgacc gcaaggccgt gcgcgagccc tactgggccg gcgccgaccg
    14881 acgcgtgcac tgacaacacc ctcctcaaga ctcatcaaga gagaccgcac atgaccttct
    14941 cgttccgccc cacctacgac gacccgcagc tcgccggact cgtcgaccgt ctgcgcacct
    15001 acctggacgg tgaactcgcc ggctacgagc gggaacgggg catcacgcat gagacccggc
    15061 tcacccgcgc cgacctcgaa cccgtctggc ggcgcagtcg cgaactgggc ttctacggca
    15121 tccacctccc cgaggagtac gggggccagg ccctcagcaa cgtccggctc gccgcgctca
    15181 aggaggagat cggcgcctgc gggcgagtcc tcgggcactc ggtgctcggt gacatgggcg
    15241 gaccgctgcg ggccggggac atcctgaagt acgccacgga gcaccagctc accacctatc
    15301 tgctgcccct cgtacgcggt gagcgggcct gttgtttctc cctcaccgag gccgacgccg
    15361 gctccgacgt gcggtccatg accaccaccg ccacaccgga cggggacgga taccggctga
    15421 ccggccacaa ggtgttcagc tcggcggggc ccttcgccga cttcgcgatc gtggtggcga
    15481 ggacggcggg cacggagaac tccttctccg cgttcctggt cgacctggac agccccggtt
    15541 gccgtgtggc ggagggcgcc accccgatgt cgggcgagca catcgagagc gacatcatcc
    15601 tggaggactg ccacgtcccg gccgccaacc tcctggggga acagggccag ggcctgaaga
    15661 tcgcgctggg ccgggtgacg aacaaccggc tgctccactg ccccaccgcc atcggcgccg
    15721 cccgccgcgc cctccatctg acccgcgacc gggccctgac gcgcaaggcc gcgggcggcc
    15781 ggctcctgat ggagatgcag tccatccagc acaagctggc cgacatggcg acggagctct
    15841 acgcggcccg ctcgatgacc tacgccgctc tcgccgccct ggacggcgga tcggacgtcc
    15901 gcgcggaagc gttcatgtgc aagctgttcg tcgcggaatc ggcgttccgc atcctcgacc
    15961 aggccgtcca gatccacggc aaggacgggc tcacccaggg caacgagatc gagtacctct
    16021 tccgcaagat gcgcatgttc cgtgtcctga ccggaacctc cgagatccag cgcaacggca
    16081 tcgccaagtc gctggtgacg cttgcctgat gaggccgcat ccggccccgc accgagacga
    16141 gacggcacca tgacccacac ctcgcaggac cacgactccc ccgccgacgg ccccgacgac
    16201 gcggaggact tcgcggacgc cgcccggggg ttcatcgccc ggctggagcc gggcgccgtc
    16261 cacgacgcca ccggacgtct ggtctgggac gccgacgcct acgccttcct cgaggaggac
    16321 tgcccgccca cggcgcaccc gtcgctgtgg aggcagagca ggctggtggc ccggcagggt
    16381 ctgttcgagg tggtgccggg tgtctaccag gtgcggggcc tggacctgtc caacatcacc
    16441 ttcatcgagg gccggcacgg cgtgatcgtc gtcgaccccc tcatcagcac ggaggtggcc
    16501 gccgccgccc tctccctgta ccggacccac cgcggtgagc gccccgtgac gggcgtcgtc
    16561 tacacgcact gccatgtgga ccacttcggc ggggtacgcg gcatcatcga cccggccgaa
    16621 gccgcctccg gccgggtgcc ggtcatcgct cccgccggat tcctggagca cgccgccggc
    16681 gagaacgtga tgacgggccc ggccatgggg cgcaggtccg gatacatgta cggcgccgct
    16741 ctgcccaagg ggcccgccgg gcagatcggc tgcggtctcg ggcagaccac ctcgctcggc
    16801 ggcatctcgc tgatcgcgcc caccctcgac gtcaccgcca ccggccagac ggagaccgtc
    16861 gacggcgtgc gtctggtctt ccagctcacc cccggcaccg aagccccggc cgagatgaac
    16921 ttccacctgc cggacctgcg cgtcctgtgc gtggcggaga acgcctgcca caccctgcac
    16981 aacgtgctga ccctgcgggg agccctcgtc cgtgacccca gcgcctgggc ccgctatctc
    17041 accgagacgc tcgccctgtt cgccgacgac accgacgtgg tgttcgcctc ccaccactgg
    17101 cccacctggg ggcaggaccg ggccgtgcgg ttcctggagg agcagcgcga cgcctacgcc
    17161 tacctccatg accagtgcgt acggctgatc aacgcgggcc gtacgggcgc ggagatcgcg
    17221 gaggagctgc gctatccgcc cgcgctggag cgtgcctggc acgtccgcgg ctactacggc
    17281 tcgctcagcc acaacgccaa ggcggtctac cagcggtaca tgggctggtt cgacggcaac
    17341 cccgcgcacc tgtggcagca cccgccgcgc gagggggcgg agcggtacgt cgcgttcatg
    17401 ggcggggcgg acgcggtggt cgacaaggcc cgcgcctcgt tcgaagccgg tgacctgcgc
    17461 tggaccgcgg aggtcctcag ccatgtgctg ctcgcccggc ccgagcacgc ggcggcccgc
    17521 gctttgcagg cctcggcctt cgagcagctg ggccacgggg cggagtgcgg cccgtggcgc
    17581 aacttctacc tcatgggcgc catggagctg cgtgaaggcg tacgcggcac cccctcccgc
    17641 ggagcacccg acatcatcgc ggccctgacg gtcgagcaga tcttccggtc catggccgtc
    17701 cggatcaacg gcccgcgagc ggcggcggct ggccggatac tcctgcgctg ggagatcacc
    17761 gcaccggagc ccgcgccggg gagccccggc acggccgaga cctggaccgt tctcctgtcc
    17821 aacggcgcgc tcaccccgat gcgcggcggc gcgccgcgcg gggaggaccc ggacgtgacg
    17881 ctgcggctgc cgcgaaccgt cctcgacgcc gtgatgagca gggccaccac cttcgccgac
    17941 gcgatcgccc gcggcgacgc cacggtggag ggcgacgtac ggaccctgct caccttcggt
    18001 tcgctcaccg accggcccga cacccgcttc ccgatcgtca cacggtaggg cgctttcacg
    18061 cctccacgac cggccgccgc tcggtgccgc tctgcccgcg cagccggcgg cgcagcgcgg
    18121 cgagccgggg gtggcgctcg ctgagctccg ccgagtggcg gtccagttcc tgcatgaggc
    18181 gctcggtgcg cttgtcgagg tccagctcgt cgaggatgcg gtcgatctcg gcgagcagcg
    18241 caccgtgcag ctgccactgc cgggggtact cctgcacatc gcgcagaagc atctcggcga
    18301 cccggtcgcg ggtgatccgg ctcgcggcca gggtggcggt cagccgctcc tcggcctgct
    18361 cggcgttggc agtcacctgg ctggtgatca gccgggcgaa attctcgatg gcttcggcca
    18421 tctgctcgaa cagctcatgg aggccggccg acacgtccgg cgggaagagc gcttcccgcc
    18481 tgcggaactt ggccaggtcg gtcaggctcc gggtcagcac ccgcagcacc accgcgcaga
    18541 tctccagggt gtcgaggccc gtccggagga ccacccggga cagcagccct tcccgtacgc
    18601 gcgggttcat ccggaggctc tcctccgcct ggcgcaacga ggcgtcgacc tccacgatgt
    18661 cgtggtcgag gcgccgcgcc tcgtgaagtc gggcggccgc gcgcgggaag gggatgggac
    18721 cctcggcgat ctccgctccc atcgtgcgga acatacggcc catcgcgcgc gcgagcccgt
    18781 cgatggacgc ccccgccgac tgcgtccaca ccggaggggc gaacagcagg ttgaacagca
    18841 ggcccacccc ggctccgatc agtgtttcca ggacgcggtg ccaggccgcc gacgtagcct
    18901 gggagacgcc gaggaccagc atcgcgctga tcgccacctc gggcacgaat tcgttcaccc
    18961 gtacgaagcg gccgatgatc agcgaagtga agatcgtcag accgagactc caccaggtca
    19021 gaccgaccag ggtggtgaag ccgatggcga tgaggacgcc gacgacgacg gcgttcacgc
    19081 gccggatacc ggtggtgagg gtcgcgtaca gagtgacctg gacgaccagg agcgcggtca
    19141 gcggagccgt caggggagcg ggtcgcgggg gcaggaccat cagggcgacg ccgaaggaga
    19201 tgacggcggc ggccgtggaa cgcagcgtct gcgccgcaac gggttcggtg gtccgccgca
    19261 ccagtttgat cacgggggca gatacgtcgg gcatgtcctt cacgtgcccg atcatgaacc
    19321 gttcatcaca cttcggcccc tggaacccct cgcgccatgc cacgtcccct ctcggctcat
    19381 gtgctgccga cgccctggtc cggcgggccc cccgaagggc cgttcgctcg gttctgcacg
    19441 gcctccgcga tccgctgggc ggtctggccg ggtgtgaggt gggtggtgtc gacgacctcg
    19501 gcctcggcgt gcagccacgt ggcggccgcc tcggcgtagg gttcgaggta ctggagccgg
    19561 aacggggagt cggggccgag gacggtgtca cccgcgatgc gcccgcggag ggtgtcctgg
    19621 tcggcgtgga ggacgaagtg ccggaccgga atggcgtgct gggcgaggcc cgagctgatc
    19681 tcgcgccagt actgctcgac caggacggtc atgggaatca ccagcgtgcc gccggtgtag
    19741 tcgaggacgt gccgggcggt ctcgaccacg agcggccgcc acggcggcca gtcctggaag
    19801 ttgcccgtcc agggcagccc cggcgtgatg tccatgagcg tctcgccgac cttctcggcg
    19861 tcgaacaccc gtgagtccgg gatcagctgc cgcacgagcg cgccggtcgt cgtcttgccc
    19921 gcgccgtggg tgccgttgag ccatacgatc atgcactcga cgttacgtcg tgcgggccgc
    19981 ggggacgggc ggagcggaaa agggtgaccc tcccgacatc accggctgcc gtgagcacgg
    20041 acgcgtcggc cgggtccgtc agccggaacc gtccagggga cgacgagtac ggcggccatc
    20101 gagagggcgg cgaggaggac gaagaggggg ccgtagccgc cgagggggac ggccagggcg
    20161 acgccggcga acggcgcgag ggccgtggcg gtcgtggtcg gtgtcgcgag gagtccggag
    20221 aggcggccat agtgggtggc gccccagcgg tcggtgatgg cggtggcctg gaggagggtg
    20281 aggttgcccc ggaccgtgcc ggccacgacc gccacggtga cgagcggact gaccgccccg
    20341 atgacggacc cgtggtcatg accgcgcgcg ggccgcgccg gtcgagggtg cgccggacgc
    20401 ggatcccggc gcgggcggag acggcgaggc cgagggagaa cgccgcggtg gtggccccgg
    20461 cgggccggcc ggtcgcggtg gtgatccgcg ggttgcggac ggggaaggcg cagtaggcga
    20521 tgccccggct cacgatgtgc gtggcgcaga gcgcgggcag ggcggcgcgg ggccgcgacc
    20581 ggtcccccgt tccggtcgcg acgccgcgca tgggggtgcc caggccggtc acgagccgca
    20641 gcagccgccc gccggggcct gttcggcagt cgcaccgacc gtggcggggg cgctcagctg
    20701 gacgagttgc ggcgtcggcg cgcagcagcc gtcggtctgc gcggtgtcgg gggcgtcgaa
    20761 gagaccggcg ccgccgcaga ctccggtctc ggggagggtg agttcgacgc ggtcggccgc
    20821 gtcgaggtca ccggcgatgg cggcgg
//
