LOCUS       NZ_CP058561            34033 bp    DNA     circular CON 15-DEC-2024
DEFINITION  Vallitalea guaymasensis strain Ra1766G1 chromosome, complete genome.
ACCESSION   NZ_CP058561
VERSION     NZ_CP058561.1
KEYWORDS    RefSeq.
SOURCE      Vallitalea guaymasensis
  ORGANISM  Vallitalea guaymasensis
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Vallitaleaceae; Vallitalea.
REFERENCE   1  (bases 1 to 5626074)
  AUTHORS   Postec,A.
  TITLE     Vallitalea guaymasensis genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5626074)
  AUTHORS   Postec,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUL-2020) Microbiologie Environnementale et
            Biotechnologie (MEB), Mediterranean Institute of Oceanography (MIO),
            UMR 7294, 163 avenue de Luminy, Marseille 13288, France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. JUNE-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018141425.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 15:20:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,859
            CDSs (total)                      :: 4,781
            Genes (coding)                    :: 4,757
            CDSs (with protein)               :: 4,757
            Genes (RNA)                       :: 78
            rRNAs                             :: 6, 6, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 5 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 7 of 24
            Pseudo Genes (incomplete)         :: 16 of 24
            Pseudo Genes (internal stop)      :: 1 of 24
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:55:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4640037
            Orig. end                         :: 4674070
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP058561.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..34033
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="triceptide"
                     /region_number="13"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..34033
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="triceptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..20909
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20909
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10909](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10909
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(412..425)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            complement(636..1757)
                     /locus_tag="HYG85_RS19890"
                     /old_locus_tag="HYG85_19805"
     CDS             complement(636..1757)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019522.5"
                     /locus_tag="HYG85_RS19890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19805"
                     /product="YibE/F family protein"
                     /protein_id="WP_212691129.1"
                     /transl_table=11
                     /translation="MRIIYLLILCFFIIKPIDVNCTEEISYEWKYIHGKVISVIEDTVD
                     EENCMRYQKLLVKLTERDLTGEAEIENVINTASIYKIVVKPGDEIIIVCNQTGDTIENG
                     RVYSYARDKYLIYLLLVFMGALLLFGGKNGFYSIISLTICVSLILFGFFPLIMKSYNPI
                     IVVSVISVISTLITLSVIGGLNIKTYAAIIGTIGGVITSGLLTFYFGALTHIQGIGDED
                     VELLSYFTEGYNLNFRDLLYAGIIIGALGAIMDVSMSIASSMGELYESNPRIGKDKLFT
                     AGMRIGKDIMGTMSNTLILAYAGNSISMILVFFLYNRSLVQFINSDQIAGEILRALCGS
                     IGLIFSIPITSIAFISISKKRNNYVKPKAVYRK"
     misc_feature    complement(1713..1726)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.62"
                     /tool="antismash"
     gene            1910..2866
                     /gene="spoIIIAA"
                     /locus_tag="HYG85_RS19895"
                     /old_locus_tag="HYG85_19810"
     CDS             1910..2866
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779095.1"
                     /locus_tag="HYG85_RS19895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19810"
                     /product="stage III sporulation protein AA"
                     /protein_id="WP_244971229.1"
                     /transl_table=11
                     /translation="MKKETVEKILTTNLRGWFGSLKKEQLDLLQEIRLRVNKPLIIRID
                     NKEYFLNQDKLVTSSKRAYIITEKDLKDTMEFISNYSLYAFEDELRNGYITVDGGHRVG
                     LAGKVVVENNRVKTIKNITCINIRISHEIKGCANKVMPYIFQENRIYHTLIISPPRCGK
                     TTLLRDIVRQLSDGVSDKTGITIGVVDERSEIGGCYRGIPQNDVGIRTDILDGCPKTEG
                     MLMLIRSMSPEVIAVDEIGSSEDIEAIDFVINAGCKMICTVHGSSLVEVKNKPILEKLI
                     DKNIIERFIVLESKNGVGDVKKIYDKQGKMISIVVDN"
     gene            2884..3405
                     /locus_tag="HYG85_RS19900"
                     /old_locus_tag="HYG85_19815"
     CDS             2884..3405
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021090.5"
                     /locus_tag="HYG85_RS19900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19815"
                     /product="stage III sporulation protein AB"
                     /protein_id="WP_113675649.1"
                     /transl_table=11
                     /translation="MVVKILGATLILISSSLLGFYYSKSYIRRSNDLRILKKALILLRG
                     EINYSLSPMPEALEDISKRFDHEIADFFKSISEELKLNSGKSLTEVWKKKAEEILKRTY
                     LNPTDIKNIMIFSENIGYLDKEMQNNNINLLLEQINEEIKVTMEDDAKYNKLYRSLGVL
                     GGILVIVLFI"
     gene            3449..3643
                     /gene="spoIIIAC"
                     /locus_tag="HYG85_RS19905"
                     /old_locus_tag="HYG85_19820"
     CDS             3449..3643
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008704108.1"
                     /locus_tag="HYG85_RS19905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19820"
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_113675648.1"
                     /transl_table=11
                     /translation="MDISIVFKIAAVGIVVAVLNQLLKKAGKDEQAMLTTLAGLVVVLY
                     WIVEYISELFEKIQTLFQL"
     gene            3719..4105
                     /gene="spoIIIAD"
                     /locus_tag="HYG85_RS19910"
                     /old_locus_tag="HYG85_19825"
     CDS             3719..4105
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAD"
                     /inference="COORDINATES: protein motif:HMM:TIGR02849.1"
                     /locus_tag="HYG85_RS19910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19825"
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_113675647.1"
                     /transl_table=11
                     /translation="MEAVQVVIIGIVSTILIVVLKKSNAEFGIYIGIAASIVIFFIIID
                     KLGVILDLISRITGLININDIYIKILLQILGIAFITEFGAQLCKDAGQQAIASKIEMAG
                     KIMILIISMPVILSIINMITNILI"
     gene            4154..5314
                     /locus_tag="HYG85_RS19915"
                     /old_locus_tag="HYG85_19830"
     CDS             4154..5314
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021088.5"
                     /locus_tag="HYG85_RS19915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19830"
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_212691131.1"
                     /transl_table=11
                     /translation="MRRIRWLLIIVIALKLSSISVFASSELDSILAEQEKVIEYDDIQS
                     AVDEILSNEEGLKIDFRETLNKVISGDLDLNFNDMFGLVLDNIFIEVKGNIKLIIELIA
                     IALIAAVFTNFTTAFNNKYVGEVGYFVVFLLMSTIILKSYNILNTIALQVISNLQTFIK
                     TLIPSLFAATALSGNYTSTFLYSQIMLIIIGVVENIILKYVVPFVYIIIVLEIINSITE
                     ESILSKMVELFKNIVNWGIKVLVIVFAAVLTMQSFTTPVIDGIANKSVKVAVSAIPFVG
                     TTLSGVADTVLGCAVLIKNGIGIVALIIIIVICLIPIIKILVVTLLYKFASAIIQPISD
                     KRIVNCLSNVGDICFILLGIVIITAFLFIITITIILNATSITAYIR"
     gene            5342..5959
                     /locus_tag="HYG85_RS19920"
                     /old_locus_tag="HYG85_19835"
     CDS             5342..5959
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021121.5"
                     /locus_tag="HYG85_RS19920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19835"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_212691132.1"
                     /transl_table=11
                     /translation="MEAFYSFIKNIVIFLLLAKILEYLIPGGNMKKYFRLFSGIILMII
                     IINPIIKYNGILEQFNYDVIKNQFKINYTDTQETENKYANVQNEITLKIYKDKIINHVK
                     GLLEAEKISITKASVEIEEDIKNENYGTIKEINLTVNSEYIEKKDSQIDRVEIEKIIIG
                     ESNDNRELRSSEDILLEKKIKKIIKNFYKLSSNNIHITIETC"
     gene            6006..6608
                     /locus_tag="HYG85_RS19925"
                     /old_locus_tag="HYG85_19840"
     CDS             6006..6608
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS19925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_19840"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_212691133.1"
                     /transl_table=11
                     /translation="MKLDFFTKGNKTEKDKKRISFLFIMFLTGLLLLLFSKNLIKPSNN
                     TKVDNSIIAPNTYKASDPQTYEEKLEKRLEKEFANIDGVGKVEVIIMLKTSGEIIINKD
                     TPNSQTQSDEVDSEGGTRQNIQTDSREATVLINNSDGSTKPIILKELEPEISGVVIIAE
                     GGDDILVKKNLINAAKVLLDVPMHKIEVMKMVQNKGE"
     gene            6611..7426
                     /locus_tag="HYG85_RS19930"
                     /old_locus_tag="HYG85_19845"
     CDS             6611..7426
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024097.5"
                     /locus_tag="HYG85_RS19930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19845"
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_212691134.1"
                     /transl_table=11
                     /translation="MQTFKKNQIIITALVIMIAIAGYLQFTENDGTPTQEVLNNQSEDQ
                     KKDNVTTPTALVPNGENANTDAKTEENAADDVSENQSPNSIAKQPEQKQEQKQEQKQGE
                     NKAAEPASTVPENENKEEKKEEAKETSSDKNDSNVGEAILTSGNTLQAGYFLQKKIDRE
                     QDYSKLKEGYLSIIDNQNLKDENKVEAVKEMIDLQDRIEKEAAAESILEAKGFKDVFVR
                     MIDNKVDVVINAKELSQADLAKVEDVVRRQTGVDAENIVITLLDVTKAQ"
     misc_feature    7610..7628
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.31"
                     /tool="antismash"
     gene            7612..7986
                     /locus_tag="HYG85_RS19935"
                     /old_locus_tag="HYG85_19850"
     CDS             7612..7986
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006857647.1"
                     /locus_tag="HYG85_RS19935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19850"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_113675642.1"
                     /transl_table=11
                     /translation="MDRQTVKIHEKDKVGEVHIADEVIAIIAGLAATEVEGVAGMVGNF
                     TGDLVEMLGKKNLAKGVLVDVGEKDVSLELSLIVDFGSSIPEVTNNVQEKVKNAVETMT
                     GLEVDEINIRVAGVNVEKSK"
     gene            8157..8552
                     /gene="nusB"
                     /locus_tag="HYG85_RS19940"
                     /old_locus_tag="HYG85_19855"
     CDS             8157..8552
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009245825.1"
                     /locus_tag="HYG85_RS19940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19855"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_113675641.1"
                     /transl_table=11
                     /translation="MNRRIMREHIFKLVFAIEFDEEERFTDRVGVYLDELETSDTAKEY
                     IKHKAISIFEKLESIDEMINKNAEKWSISRMSKVDVSILRVAIYEIKFDEDIPTNVAIN
                     EAIEIAKKYGGDHSPSFVNGILAKVVN"
     gene            8567..9787
                     /gene="xseA"
                     /locus_tag="HYG85_RS19945"
                     /old_locus_tag="HYG85_19860"
     CDS             8567..9787
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012200528.1"
                     /locus_tag="HYG85_RS19945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19860"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_212691135.1"
                     /transl_table=11
                     /translation="MKKSIFSVSQVNAYIKKIFVNDYVINDIWIKGEVSNCKIHRSGHV
                     YFTLKDNNSAISCVVFKNYRDFVECELRDGINITARGYISVYERAGTFQLYVQQIKSDG
                     MGDLYKKFEILKENLQIKGYFDSDNKKKIPRYPRRVGIVTSDTGAAVRDIINVSKRRNP
                     YIGLVLYPSLVQGEGAANNIVKGIKYLDRVTDVDVIIIGRGGGSIEDLWAFNEEIVAKA
                     IYEANTPIISAVGHETDFTISDFTSDLRAPTPSAAAELAIPAFDEIDGILEKYNYKLTN
                     SMNNKIESCIKAIQLNKIKLDFNSPSMRVLKERQYITEFEDRLNRRIKELINDNKNYVS
                     LLQNKLSVLSPITNLEKGYSYIENTHGQVKSITDVNMGETLLIQLHDGKIEAEVKNIES
                     GKWGSHE"
     gene            9780..9971
                     /gene="xseB"
                     /locus_tag="HYG85_RS19950"
                     /old_locus_tag="HYG85_19865"
     CDS             9780..9971
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601005.1"
                     /locus_tag="HYG85_RS19950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19865"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_113675639.1"
                     /transl_table=11
                     /translation="MSNKLTFQENLDSLEKIVERLESGETTLEESLELYKQGMMFLKEC
                     NSKIDKVEKEIEVVQNEN"
     gene            10001..10909
                     /locus_tag="HYG85_RS19955"
                     /old_locus_tag="HYG85_19870"
     CDS             10001..10909
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008369266.1"
                     /locus_tag="HYG85_RS19955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19870"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_244971230.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2e-51, bitscore:
                     172.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRVMNFSNELKDKQQVVEKILLKYMPENASPYDHVVYNAMKYSL
                     MANGKRIRPILMMESYKICGGNNIREIEAFMAAMEMIHTYSLIHDDLPAMDNDDYRRGI
                     LTCHKKYGEDIAILAGDGLLNSAYEIMIDACLKDNKVKAKQKLTACKEIGKAAGVKGMI
                     GGQVADVIQNDITMDVINYIHIHKTSAIIEASLTAGAVLANGSMQKVETFRKIGRCIGL
                     AFQIQDDILDIVSTTEELGKQVGSDNKNGKNTYVTIKGIEESRQIVNELIEKALDSLNS
                     FDSSEKEFLEEFIFYLRNRKK"
     gene            10920..11363
                     /locus_tag="HYG85_RS19960"
                     /old_locus_tag="HYG85_19875"
     CDS             10920..11363
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014711.5"
                     /locus_tag="HYG85_RS19960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19875"
                     /product="divergent PAP2 family protein"
                     /protein_id="WP_212691136.1"
                     /transl_table=11
                     /translation="MENFYTITENRVLLAAVIAWFVSQGIKFFTCLIKTRKIRMDRIMG
                     SGGMPSSHTASVMAATFSVGELLGYNNPVFGGLMIISFIVMYDAAGVRMAAGKQARAIN
                     NIVEALGSYRLKIDGQLKELLGHTYMEVLVGAALGIVIALLIN"
     misc_feature    complement(11943..11953)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            12127..12708
                     /locus_tag="HYG85_RS19965"
                     /old_locus_tag="HYG85_19880"
     CDS             12127..12708
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS19965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_19880"
                     /product="hypothetical protein"
                     /protein_id="WP_113675636.1"
                     /transl_table=11
                     /translation="MSKNKTKVKFRSLYTHKKINTLWIGIITVITLITAILLGYIALVL
                     MDNVSLYGAIFIVLVIVLLGIFFDLLGIAVTAAEETPFHSMAASKVRGSKESITIIRNA
                     GAVANFFNDVIGDISGIISGLATGVIVLKLVAKFAIQDTIINVLLTGVIAAITVGGKAI
                     GKEIALRHSNLIVYKLGVIYSLFRKQNKNK"
     cand_cluster    12663..34033
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="single"
                     /product="triceptide"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    12663..34033
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[22662:24033](+)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      22663..24033
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="2"
     gene            12738..14609
                     /gene="dxs"
                     /locus_tag="HYG85_RS19970"
                     /old_locus_tag="HYG85_19885"
     CDS             12738..14609
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004078848.1"
                     /locus_tag="HYG85_RS19970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19885"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_212691137.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.1e-123,
                     bitscore: 409.9, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-05, bitscore:
                     22.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEILDGISSPSDIKALEIDQLNILAKELREYLIKVVSNTGGHLS
                     SNLGVVELTLALHYCFNSPYDKLIWDVGHQTYIHKMITGRKEEIKTVRKFQGLSGFPKR
                     AESEHDIFETGHSSTSISAALGFAKARELLNENNYVVPIIGDGSMTGGMAFEALNNAGR
                     LDSNFIVILNDNQMSISRNVGGLSSYLDTIRTGTVYKEMKEEVEKALTKIPRIGKEVVK
                     VIRDVKSGIKQLVIPGMLFEELGFTYLGPIDGHNISALIKTLNQAKRLNEPVLIHVNTI
                     KGKGYKPAELNPTKYHGTKPFYIKNGRPKNLPCSDTYSKVLGDTLIDIADNKKKGIVAI
                     SAAMPEGTGLDKFARKYPDKFIDVGIAEQHAVTYAAGLAASGIKPVVALYSSFLQRAYD
                     QIIHDVCMQRLPVVFAIDRAGLVGEDGETHQGIFDISFLSHMPNMTVIAPKNKSELQSM
                     IKFAVDYEAPIAIRYPKGKASNELKEYNEEITYGKSEIIKRGSKIAIIGVGTLTQTAYN
                     VSAMLEENNIMCTLINARFVKPIDKELIEEIANNHDYIFTIEENVVSGGYGNNVVKFVS
                     DTQANTKVVCIGIEDDFIQHGKRDELIKLCKLDEESIYNRIMTYVNK"
     misc_feature    12753..12772
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 19.55"
                     /tool="antismash"
     gene            14657..15469
                     /locus_tag="HYG85_RS19975"
                     /old_locus_tag="HYG85_19890"
     CDS             14657..15469
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584723.1"
                     /locus_tag="HYG85_RS19975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19890"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_212691138.1"
                     /transl_table=11
                     /translation="MVQKERLDILLFNKGLADSREKAKSIIMTGNVFVNGEREDKPGTK
                     FDIKSEIIVKKNPNPYVSRGGLKLDKAVKEFGLKLENKVCTDVGASTGGFTDCMLQNGA
                     KKVYSIDVGYGQFAWKLRQDERVVCMEKTNVRYVTKDMVDDEIDFVSIDVSFISLTKVL
                     EPVKKLMSENSEMVCLIKPQFEAGREKVGKKGVVRDRAVHEEVIEKIMKYVLSIDFSIK
                     DLSFSPIKGPEGNIEYLLYLTTEGQSTMDDEEIISIVKTVVDKAHEKL"
     gene            15562..16425
                     /locus_tag="HYG85_RS19980"
                     /old_locus_tag="HYG85_19895"
     CDS             15562..16425
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039482.4"
                     /locus_tag="HYG85_RS19980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19895"
                     /product="NAD(+)/NADH kinase"
                     /protein_id="WP_113675633.1"
                     /transl_table=11
                     /translation="MNKFVIIPNLTKDKKLETTKLIVDWLEKNDCKICLPAQIANYINK
                     QQYSCSESDMYNNADCAIVLGGDGTILNAARNLIKYDLPILGVNLGNLGFLAEVEKKDA
                     LSTLSKIIKGDYYVQRRMMLDVKRLINDKEDLIGVALNDIVIARTSISRMMKYSIYVND
                     GHVNNYSADGIIVSTPTGSTAYNLSAGGPILDPKNEMMVITPICPHTLMSRSIVLSKND
                     VVKISLENNRKSWNDDTMITIDGQESFNIDQKDKIIISNSYKSAKLITCNKNGFYTILK
                     KKLGNC"
     gene            16505..16963
                     /gene="argR"
                     /locus_tag="HYG85_RS19985"
                     /old_locus_tag="HYG85_19900"
     CDS             16505..16963
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012200522.1"
                     /locus_tag="HYG85_RS19985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19900"
                     /product="arginine repressor"
                     /protein_id="WP_212691139.1"
                     /transl_table=11
                     /translation="MKIERQTKILQLINHYDIETQEDLASRLIEEGFIVTQATISRDIR
                     ELRLTKIATSDGKQKYVVLKNKETKLNEKFIRVFKDGFSSMDRAGNIIVLKTLVGMAMA
                     VAAAIDALNFDDIVGCIAGDDTIFCAVRTENDAIRIMEKMNKLVNNNL"
     gene            17017..18714
                     /gene="recN"
                     /locus_tag="HYG85_RS19990"
                     /old_locus_tag="HYG85_19905"
     CDS             17017..18714
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: protein motif:HMM:TIGR00634.1"
                     /locus_tag="HYG85_RS19990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19905"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_113675631.1"
                     /transl_table=11
                     /translation="MLIHLHVKNYALIDEINVDFDDNLNILTGETGAGKSIIIGSINAV
                     LGGKVSKDMIRTGCDSALIELLFYVDNNVVLSKLHEYDINMDNNKELLITRKININGRS
                     VFRMNGQVVTTSIVKDISTKLIDIHGQHEHQSLLNKKNHLSLLDTFCGVDVLELKEKLR
                     EKYAYYMELSSKIDHFMLDEHTRKKEISFLEYEINEITSANLIIGEDEKLKEEYTLLSN
                     GKKIIKSMSEIHTYVNGDSTNMTGAIDQIGQAVRLLSGIKTLDKNIMNMEEQISNIEIM
                     LSDFNRDINDYISSFELDESRYFEIEDRIDLINNLKMKYGDTIEEILKYKEEKEKYLEE
                     LINHEEHLNQINKEINTLKNEIEVYCGDLTRIRKEKAKHISKLIVNALRHINLLNTNFI
                     IEVNRANKFNSNGWDEIEFLISTNVGEPLKSLSKVASGGELSRIMLAIKSVLAGSDDIE
                     SLIFDEIDTGISGKTAGLVAEKLVQISKEHQVICITHLAQIAAMGDAHFIIQKKVKDNV
                     THTLINKLDKESSINELARLLGGIKITDAVIANAKEMKDYAEEVKKIQ"
     gene            19006..20289
                     /gene="spoIVB"
                     /locus_tag="HYG85_RS19995"
                     /old_locus_tag="HYG85_19910"
     CDS             19006..20289
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: protein motif:HMM:TIGR02860.1"
                     /locus_tag="HYG85_RS19995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19910"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_212691140.1"
                     /transl_table=11
                     /translation="MRSKGYRFRIFLFFSLLVILVINVGSDLLISRYLPGEIKILVNEE
                     RDFLFNVPLDAKINGNLEGVVMVNQEPVKDNLVLNLQKSFTIKPKKTGVIDVELKLFGI
                     LPIKTVKVDVIDKKRVVPVGKTIGVTVYTDGILVLGTGLVYGEDGKKYNPAKGKLYTGD
                     YIKAVKGKQISRKKELIEIVKKNQGEQIELDVIRNDKKQKVNITPVKTIENNQYKIGVW
                     VRDDTQGIGTMTYMDLDKKTFGALGHGITDVDTKQLIEIETGEVVNTMITTIKKGEDGV
                     PGEISGIIVGGEGNRLGEIKKNTSHGIFGEASNEGIDQVLENDIIPIGFRYDVHEGQAF
                     IRSDVSGKLKDYEILIKKIYLGDESNKGMIIEVVDEDLIKTTNGIIQGMSGSPIIQDNK
                     LIGAVTHVFVQDSKKGYGVFIENMLIEE"
     gene            20527..21282
                     /gene="spo0A"
                     /locus_tag="HYG85_RS20000"
                     /old_locus_tag="HYG85_19915"
     CDS             20527..21282
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /GO_process="GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006857710.1"
                     /locus_tag="HYG85_RS20000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19915"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_242986550.1"
                     /transl_table=11
                     /translation="MCTILSEYLNSKEDITVVGVANNGEDACKQIKEKEPDVVLLDIIM
                     PQLDGLGVLERMYEDKDIKKVPMFIMLTAVGQEKITSSALNLGAEYYIMKPFDNETIVK
                     RIRQLKGKMQLIKRDRRNDFVSETEKGYSARSLEAEVTNIIHEIGVPAHIKGYQYLRDA
                     IIMAINDMDILNSITKLLYPSIAKKFNTTPSRVERAIRHAIEVAWGRGKMDTIDKLFGY
                     TINHGKGKPTNSEFIALIADKLRLELRVG"
     gene            21548..21694
                     /locus_tag="HYG85_RS20005"
                     /old_locus_tag="HYG85_19920"
     CDS             21548..21694
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS20005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_19920"
                     /product="hypothetical protein"
                     /protein_id="WP_193774759.1"
                     /transl_table=11
                     /translation="MAKEKVKDKGGSLGGLSKSYNNNRSVNGKIKNSKDTTSRNSDNLS
                     HKD"
     gene            21818..22384
                     /locus_tag="HYG85_RS20010"
                     /old_locus_tag="HYG85_19925"
     CDS             21818..22384
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="HYG85_RS20010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19925"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_212691141.1"
                     /transl_table=11
                     /translation="MPKIVDTEAIRIEIIKKAFDVFVKKGYYKSSMTDITKSCNMKRTT
                     IYHYFKNKDEIFEQTVLYVIETLENDIIDISNDDDMTLMKKIKYLTNKWDNEFSNNNIL
                     LLLVEMWFAIKREEGELFDRIKKRITLMNKSINKIVVQKAKYMVNSKRDKKQLIEYSMI
                     MSILNQVSLEKGFLSESIISVISSF"
     gene            22663..24033
                     /locus_tag="HYG85_RS20015"
                     /old_locus_tag="HYG85_19930"
     CDS             22663..24033
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860000.1"
                     /locus_tag="HYG85_RS20015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19930"
                     /product="radical SAM protein"
                     /protein_id="WP_212691142.1"
                     /sec_met_domain="PF04055 (E-value: 4.1e-17, bitscore: 61.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 9.5e-07, bitscore: 27.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.5e-06, bitscore: 26.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSPKSFFSKVAIKEGIKYLEKDPITNFPKLIDWAGKIPMLPSQR
                     HQYEAIIDMWQDKDSIWHGFIERILTKIHPNIRKTLLMNFTINAGIEGLKLIDANKEKY
                     DCNIPWAILMDPTSACNLKCIGCWAAEYKKNDSLDYDTLSNIIKQGKELGTYMYIYSGG
                     EPMVRRDDIIKLAREHNDCVFLAFTNGTLFDEDYAKKLQEVGNVTFAISIEGYEEQTDM
                     RRGKGTYQKVIKGMDILREHGIPFGFSSCYHNKNEEIVSSEEYIDFMIEKGCYFGWIFT
                     YMPLGKDAVLDLLATAEQRKDMYYKVREYRKTKPIFTMDFWNDGEYVNGCIAGGRNYLH
                     INANGDVEPCAFIHYSNANIKEVSLLDALRQPLFRQYRKHQPFNDNMLRPCPLLDNPEM
                     LKKMVHESGALSTQPMDREDVDELTTKTKEAAEKWAPVAEELWEESHGCINCKAANQ"
     gene            24081..24782
                     /locus_tag="HYG85_RS20020"
                     /old_locus_tag="HYG85_19935"
     CDS             24081..24782
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020893.5"
                     /locus_tag="HYG85_RS20020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19935"
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="WP_212691143.1"
                     /transl_table=11
                     /translation="MKRDRRINALLLFLKLFSVFNVVVIAIIISHYWGKITPEDIFNYV
                     PDNYFLAAITIIGLFLIKSLSVVLPLMALYISSGMIFSPLWGIIVNLIGLFVSLTIPYL
                     LGRFCGKGLLDRLLVKYKNIEKLRTIKSKNEWFLSYILRMIGILPGDIVSMSLGAMNIN
                     YNKYIVGSIVGLFPRMVAATCLGSTITDPTSPVFILSCLITVVLTVGSMFLHQRYMKKE
                     DERNNVEVMTR"
     misc_feature    complement(24948..24962)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 19.28"
                     /tool="antismash"
     gene            24990..26081
                     /locus_tag="HYG85_RS20025"
                     /old_locus_tag="HYG85_19940"
     CDS             24990..26081
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /locus_tag="HYG85_RS20025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19940"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_113675625.1"
                     /transl_table=11
                     /translation="MQDNFYYSEEKLLFDNEVKVNYRIAKVLFYIAVTVIPLVIVLQLL
                     GVFIYYMVDAIMAIVTAFILLIMPRILTIVHVHKKKWFKYILLFLVIMMLPLIYLEYDY
                     MVLILWIFPLLISCMYFSNRLNTITVIFDVVVLGFTSYYRSYQRLQNNLISQRIGGLFK
                     DFIISYITYAMLVMISYVIIYLLTKKTNELLQDAIKKKEFEILSITDSMTGIYNYRYLM
                     SELEKNQELFHKENIPFAAVLFDVDHFKSINDTYGHVEGDCALQAIVKCLQNMVRENDV
                     IGRYGGEEFMVILSDTTVNEAYMIAEKCRQAISRLKIENLDTYISISGGVAEYNGENIK
                     DYIRSMDEKMYDAKNNGRNIIIA"
     gene            26288..26731
                     /locus_tag="HYG85_RS20030"
                     /old_locus_tag="HYG85_19945"
     CDS             26288..26731
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS20030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_19945"
                     /product="hypothetical protein"
                     /protein_id="WP_212691144.1"
                     /transl_table=11
                     /translation="MKFNKKLLNIPIVLMIVIAVLCLLNVPSRINMLNGISGAEKIGII
                     NINYNTEQQKNEYGEEIFVTDKQKLFNIINTINNGKIDTEATPDRGGANYELRFYKDGK
                     SIKADYWQNEKYNLSVEGVEGEIVVDKKLEQIIETIIQENSNE"
     gene            26762..27724
                     /locus_tag="HYG85_RS20035"
                     /old_locus_tag="HYG85_19950"
     CDS             26762..27724
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS20035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_19950"
                     /product="hypothetical protein"
                     /protein_id="WP_212691145.1"
                     /transl_table=11
                     /translation="MKKTTTIVSLLFAIMLMTSNVFAGNTDTLQNNFEESEDIYIELSE
                     PILLKARQYVDGLMNAHFDQVFAYSNEGFMLCLYETLYEDSDKYLNEGKVVSSEGEQIP
                     FWDPHQERMLRIDRLVKDGYIMEDELTIEIDRTVIASILYRIYKDKIPFKGSVDYPDTE
                     DIALRWAGEVGLPTFAVNTGLKIKPEDSIKSDKNFSLLYYPNDYLKIITYAYLMFPNPY
                     SGNYVDLEFIKEDVNDIKAKKIKELIMLTRKEVMKPRLGDFRRDVLNNENIGNIVDSYQ
                     KTKSYETLKKIYQIIKDSFNLFEYQDNIGYLSYKFSVCK"
     gene            27803..28423
                     /locus_tag="HYG85_RS20040"
                     /old_locus_tag="HYG85_19955"
     CDS             27803..28423
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012521.5"
                     /locus_tag="HYG85_RS20040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19955"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_212691146.1"
                     /transl_table=11
                     /translation="MTRLYLTRHGETEWNLIKKVQGSRDSNLTQKGIIQATKLGKYLEN
                     TNIDVIYSSSSGRAYNTAKIIAGNRNIEVIKMDDLKEMNLGIWEGKTFEVIKEDNEEMY
                     DTFWNKPHLVKEFPGESFSEFEKRVVGTVLDIAESNKGKDILIVAHALVLKVVMSFFEN
                     RPLEKLFEDHFMYSTCLNEVEILDGDYKIVKYNQTDHYDIEVG"
     gene            28547..30196
                     /locus_tag="HYG85_RS20045"
                     /old_locus_tag="HYG85_19960"
     CDS             28547..30196
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013584.5"
                     /locus_tag="HYG85_RS20045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19960"
                     /product="amidase family protein"
                     /protein_id="WP_212691147.1"
                     /transl_table=11
                     /translation="MKSLRTILTVVFSFAVVAAVILYTQIKKIASSNNQSKKQVDKQEK
                     DIKTTAKRPLDFSAFESDLNKLGDQRYKEIEKSLIESDIRSIQKNIESGNLTYEELVLF
                     YIKRIKEIDNNRLNTVIQLNPDAVVVAREMDEKKNNGEKLSDLHGIPVLLKDNIGTGDK
                     LTNTAGAKVLEDSSCDRDAYIVKKLREAGVIILGKTNLSEWANFMSIDSSNGYSALGGQ
                     THNPYGNYDVGGSSSGSGAGVSANFAPLAIGTETAGSIISPSSQNSVVGIKPTVGLWSR
                     DRIIPLAIDLDTAGPIARTVEDAAMLLGELVGEDENDIATSDAPEKEDYTTYLDKNGLQ
                     GMSIGIVTNKEVTSSYRNDDSDIINRIKEELINLGADVKNVELDDKAFRIDGHVDMMAY
                     EYKTGVEEYLNAIGDNAPVKTIKEITGFNKRDLDSRAYYGQYFIEKARDINITEEENTK
                     ILSHNRSNTGSAIDEALENDKVDVLISLNNYLSGIYPIAGYPAITVPAGYRDSGEPVGL
                     TITSTKFSEGLLIKAAYAYEQGTKHRIQPNMI"
     misc_feature    complement(30208..30224)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 28.86"
                     /tool="antismash"
     gene            30285..30575
                     /locus_tag="HYG85_RS20050"
                     /old_locus_tag="HYG85_19965"
     CDS             30285..30575
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS20050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_19965"
                     /product="hypothetical protein"
                     /protein_id="WP_212691148.1"
                     /transl_table=11
                     /translation="MNYIYICTVILIIISIIFFIIDTTNITSFISNDLRGFKLIISIAF
                     AILLPVTILSGVYHLNDISDNQLYIWLVKYPCVFLSFIGFQVILYRNNDIK"
     gene            30646..31164
                     /gene="dcd"
                     /locus_tag="HYG85_RS20055"
                     /old_locus_tag="HYG85_19970"
     CDS             30646..31164
                     /EC_number="3.5.4.13"
                     /GO_function="GO:0008829 - dCTP deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006229 - dUTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dcd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776977.1"
                     /locus_tag="HYG85_RS20055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19970"
                     /product="dCTP deaminase"
                     /protein_id="WP_212691149.1"
                     /transl_table=11
                     /translation="MILSGQKIRSRLGKDIFIEPYNEEQLNPNSYNLRLHNELLVYENN
                     SLDMKKSNDTKKLIIPEEGLLLEPGKLYLGRTVEYTKTDNYVPMLEGRSSIGRLGLFIH
                     VTAGFGDVGFSGYWTLEIFCVQPIKVYPEVEVCQIYYHTIDGDYDKYTSGKYQNNKGIQ
                     PSLLYRDFE"
     gene            31197..31613
                     /locus_tag="HYG85_RS20060"
                     /old_locus_tag="HYG85_19975"
     CDS             31197..31613
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016297517.1"
                     /locus_tag="HYG85_RS20060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19975"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_212691150.1"
                     /transl_table=11
                     /translation="MKVEFYNLDDFNNSLKFVVIQARYKDEWIFVRHKDRNTWEIPGGH
                     IEKGEMPDEAAARELYEETGAIEYDLSPICNYSVEINESKSFGRLYYAEVKNIGELGDY
                     EIAEIITKDELPEKLTYDKIQPILYKKVLANITI"
     gene            31649..31894
                     /locus_tag="HYG85_RS20065"
                     /old_locus_tag="HYG85_19980"
     CDS             31649..31894
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS20065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_19980"
                     /product="hypothetical protein"
                     /protein_id="WP_113675618.1"
                     /transl_table=11
                     /translation="MIIVRDRKTYKKYIVLGTGLGAYKAVRPSFFGGNLFPHEEEGTVK
                     TIAVCDSKGDIFWFESNYLQVIEVDGIKISEIDLGE"
     gene            31897..32589
                     /locus_tag="HYG85_RS20070"
                     /old_locus_tag="HYG85_19985"
     CDS             31897..32589
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS20070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_19985"
                     /product="hypothetical protein"
                     /protein_id="WP_212691151.1"
                     /transl_table=11
                     /translation="MDLLVIILFGVILISCILIRLKPFEKHRKIFGIVFILIPLIIIIV
                     SYFYDETDNIYDFIFINIYFIVLLVILTLLEKKTRENTYSYFGFFIVFYVIMFYSIRIM
                     NGRLLISLNYMVIVLTFITNIKSIYKRDDRTVMIFANIIGIIIIGIMTMIYPKSYLTST
                     KQERILNGYLINEQEIDDEDIIEITVLSNPSVNNEKRIFVKIKDEGAFIYYYKSGEITG
                     VEEKDFSK"
     gene            32604..33260
                     /locus_tag="HYG85_RS20075"
                     /old_locus_tag="HYG85_19990"
     CDS             32604..33260
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013658207.1"
                     /locus_tag="HYG85_RS20075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_19990"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_212691152.1"
                     /transl_table=11
                     /translation="MKLEEISSFFNKRVDGYEEHMMTYVDGAKEYYIETAKIIPKVEGL
                     KLLDLGCGTGLELDEIFKVNPTIMVTGIDIAKKMTDKLLDKYRNRSNQINIINESYLEY
                     NIGEDIYDVALSVQTLHHFTHKEKTKIFSKIFRSLKHNGIYVETDYIAPNQEYEDFHYS
                     ENVRMRNELGIKEGYYHYDTPCTFENEKNMLYEAGFKSVEKIWQKENTVILVAKK"
     gene            33304..33810
                     /locus_tag="HYG85_RS20080"
                     /old_locus_tag="HYG85_19995"
     CDS             33304..33810
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS20080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_19995"
                     /product="putative signal transducing protein"
                     /protein_id="WP_212691153.1"
                     /transl_table=11
                     /translation="MAWCPKCKSEYEDNVKVCKECNVELVDQLENDEVEYQNFEFLINV
                     GTVNEANILISLLESYDIPTIHKSKGSGEYLQVATGINYQGVDIYVPADVLTKAKEIID
                     YSNNVDLDDDTQTENIIEDNNNFEDEELDQLDKKNSSKRRTGLLILILLFIVLPLLIVI
                     ISWFI"
ORIGIN
        1 atgtttaaca ggagcactag aagcaaaaga tacatataca agtggtcatt ctgatagggt
       61 tgcacatatg gcatatgata taggaaaaaa atatgggctt agtaaaaaag aattggaaga
      121 cttgcatctt gccggtcatc tacacgatat aggaaagata ggtattcctg ataatatact
      181 caataaacca agtaaattac aaccacatga atataatatt gtaaaaaatc atagtagaat
      241 gggatatgac atattgatga aatcaaaaaa tcttaaagat atagctatca tagtgctgta
      301 tcaccatgaa agatgggatg gaaaaggata tccagaaggt ttaaaagaaa aggaaatacc
      361 attagcatca agaataattg caataagtga ctcaatagac gccatgattt ctgaaagacc
      421 atacaaaaaa agtttatctt gggatgaatg caagaaagaa gttgaatcca ataaagggat
      481 acaatttgac ccatgtttag taaatatcat tgaaagctta tggaacaaat gggcaaaaag
      541 cttataaaat aaaaggggct atcggataat acattttttg atattgatgt taaaaatgta
      601 ttatccgaca gcccctattt aaattattaa ttcaattatt ttctataaac tgcctttggt
      661 ttaacataat tattccgttt tttgctgatg gatataaagg ctatagaagt tattggaatg
      721 ctgaatatca agccaatact gccacaaagt gctcttaata tctctccagc tatctgatca
      781 gaattaataa attgtactaa tgacctgtta tacaagaaaa atactaaaat catgcttata
      841 gaattaccgg cataagctaa tataagtgtg ttggacatgg ttcccattat atctttaccg
      901 attcgcatac ctgccgtaaa aagtttatct ttacctattc taggattact ctcataaagc
      961 tctcccatag aagaagcaat tgacatacta acgtccataa tggctccaag agcccctata
     1021 atgattccag catataacag atctcgaaaa ttaagattat atccttcggt gaaatatgat
     1081 aataattcaa catcttcatc accaatacct tgaatatgtg ttagagctcc aaaataaaat
     1141 gttaacaaac ctgaggtaat cacaccacct atagtaccaa taatagctgc atatgtttta
     1201 atattgagac caccaataac agataatgta attaaagtgg atatgacact tataacacta
     1261 accactataa ttggattata tgatttcatt attaacggga agaagccaaa aagtatcaat
     1321 gaaacacata tggtcaagct tataatagag tagaatccat ttttacctcc aaagagtaat
     1381 aaggcaccca taaaaactaa taaaaggtaa attagatact tgtcacgagc ataagaatat
     1441 actctcccat tttctatggt atcccctgtc tgattacata caataataat ttcatctcct
     1501 ggtttgacaa caattttata aattgaagcc gtattaatca cgttttcaat ctctgcttca
     1561 ccagtaaggt ctcgttctgt taactttacc agtaattttt gatatctcat acaattttct
     1621 tcatcaacag tatcctctat gacggatatg acttttccat gtatgtactt ccactcataa
     1681 cttatctctt cagtacaatt aacatcaata ggttttatta taaaaaaaca taagatcaat
     1741 aaatagatta ttctcataac atatttgctc cttatctggt agtgagttgt tgatagttac
     1801 tttgatttat acaatatatg agatattaat tttgtttatg attaaacaaa attcttatca
     1861 taaaaaagtt ggtacaggca tatattgttt taagaaaggt ggacaagtga tgaaaaaaga
     1921 aactgttgaa aaaatattaa caactaatct tagaggatgg tttggatcat taaagaaaga
     1981 gcagttagac ttattgcagg aaatcagatt aagagttaat aaacctctta ttataagaat
     2041 agataataaa gaatactttt taaaccaaga caagttagta acaagcagca aaagagctta
     2101 tatcataact gaaaaagatt taaaggatac tatggaattc ataagcaact attccctata
     2161 tgcctttgag gacgagctgc gaaatggata tataaccgtt gacggagggc atcgtgtggg
     2221 attggcagga aaggtagtag tagagaacaa tagggtaaag actataaaaa acataacttg
     2281 cataaatatc aggatttcac atgaaataaa aggctgtgcc aacaaagtta tgccctacat
     2341 atttcaagaa aatagaatat atcatactct aataatatct cctcctagat gtggcaagac
     2401 gacattattg agagatatag taagacagct ctcagatggt gtaagtgata agacaggaat
     2461 aaccataggt gtagttgatg aaagatctga aataggaggt tgttatagag gtataccaca
     2521 aaatgatgta ggaatcagaa cagatatact tgacggatgt ccaaaaactg aaggtatgct
     2581 catgcttata agatcaatgt ctccagaagt cattgctgta gatgaaatag ggagcagtga
     2641 agatatagaa gccatagatt ttgttatcaa tgcaggttgt aagatgatat gtactgtaca
     2701 tggctcatca ctggttgaag tcaagaataa acctatactg gaaaaattga tagataagaa
     2761 tataattgaa cgttttattg tcttagaaag taaaaatgga gttggtgatg taaagaagat
     2821 atatgataag cagggcaaaa tgataagtat tgttgttgat aattaagtaa agggggttat
     2881 ttcatggttg taaaaatatt aggtgctact ctaatactta tatcatcttc acttttaggt
     2941 ttttattata gtaaaagtta cataagaaga agcaatgacc ttagaatatt gaaaaaagcg
     3001 ctgatcctgt taagaggtga aatcaattac tcattatctc caatgccaga agccttagaa
     3061 gatatcagta aaagatttga ccatgagata gctgattttt ttaaatccat atcagaagaa
     3121 ctaaaactca attcaggaaa atcattgaca gaagtatgga agaaaaaagc tgaagaaata
     3181 ttgaaaagga cttatttgaa ccctacagat attaaaaata ttatgatctt cagtgaaaat
     3241 ataggctatc tagataaaga gatgcaaaat aataacatca atctgcttct agagcaaata
     3301 aatgaagaaa taaaagttac tatggaagat gatgccaaat acaataaact gtatagaagc
     3361 cttggagttc ttggaggtat attggtcatt gtacttttca tatagcaaaa gataatttga
     3421 cgtgccttat tctgagggga gggtaataat ggatatatct attgttttta aaatagctgc
     3481 agttggaatc gtggttgcag tcctcaacca attattaaag aaagcaggaa aagatgaaca
     3541 agctatgtta actacactag caggattagt tgttgtcctt tattggattg tggaatatat
     3601 aagtgaactg tttgaaaaaa tacagacgtt gtttcaacta tagaaaatac attgaactta
     3661 ttgaaatgga tttatagaga tttaatgtat atagggaaaa tctgaaagga atgttttgat
     3721 ggaagctgta caagttgtca ttatcggtat tgtatcaaca atattaatag ttgtactaaa
     3781 aaaaagtaat gctgaatttg gtatttatat aggtattgca gctagtatag ttattttctt
     3841 tattattatt gacaagttag gagtaatact ggatctgata tctaggatta caggtttaat
     3901 caatataaat gatatatata taaagatact actgcaaata ctgggaattg ccttcataac
     3961 agaatttggt gcccaattat gtaaagacgc tgggcagcaa gcgatagcaa gtaaaattga
     4021 gatggcagga aaaataatga tattaattat atccatgccc gtaatactat caatcattaa
     4081 tatgataact aatatcttaa tatagattgc tgcatacacg gtcaatcagt tttaaatgaa
     4141 ttaggagaat actatgagaa gaattagatg gttattgata atagttatag ctttaaaatt
     4201 atcatctata agtgtgtttg cttcatcaga actagatagt atattagcag agcaggaaaa
     4261 agttattgag tatgatgata ttcaatcagc ggtggatgaa atactcagta atgaagaggg
     4321 gcttaagatt gacttcaggg aaacattgaa caaagttatt agcggagatt tggaccttaa
     4381 cttcaatgat atgtttggat tagtgttaga taatatcttc atagaagtaa aaggaaatat
     4441 aaaattgata atagaactta ttgccattgc cttgatagca gcagtattca ctaattttac
     4501 tactgctttt aataataaat atgtaggcga agttggctat tttgttgttt ttctattgat
     4561 gtcaaccata atattgaaat cgtacaatat attgaatact atagcacttc aagtaatatc
     4621 taatctacag acctttatta aaactttgat acccagctta tttgctgcta ctgctttgtc
     4681 ggggaattat acttcaactt ttctctacag tcagataatg ctaatcataa taggcgtagt
     4741 agaaaacatt attctaaaat atgtagtacc ttttgtatat ataattatag ttcttgagat
     4801 aattaacagc attacagaag aaagtattct atccaagatg gtggaactat tcaaaaacat
     4861 agttaattgg ggaatcaagg tacttgttat cgtttttgcg gcagttctta ccatgcagag
     4921 ttttacaaca ccagtcatag atggtatagc taataaatct gtcaaagttg cagtatctgc
     4981 catcccattt gttggtacta cattaagcgg tgtagctgat acagttctag ggtgtgcagt
     5041 cttaataaaa aatggaatag gtatagtagc attgataatc atcattgtga tatgcctgat
     5101 accaataata aaaatacttg ttgtgacttt attatataaa tttgcatctg ccataatcca
     5161 accaatatcc gataaacgta tagtcaattg tttatccaat gttggggata tatgttttat
     5221 actccttgga atagttatta ttaccgcttt tttatttata atcacaataa caataatctt
     5281 gaatgcaaca agtattacag cctacataag ataaaatatt attcaatgaa ggaatgaaga
     5341 tatggaagca ttctatagtt ttataaaaaa catagttata tttttattat tagccaagat
     5401 attggaatat ctcatacctg gtggcaatat gaaaaaatat tttcgattgt tttctggaat
     5461 tatcttgatg attataataa ttaacccaat aatcaaatat aatgggatac tggaacaatt
     5521 caattatgat gttatcaaga atcaatttaa aattaattat accgatactc aggaaactga
     5581 aaataaatac gcaaatgtcc aaaatgagat aaccttgaaa atttataaag ataagataat
     5641 caatcatgta aaaggactgt tggaagctga aaaaatctct ataaccaaag cttcagtaga
     5701 gattgaagaa gatatcaaaa atgaaaacta cggtactatc aaagaaataa atctcacagt
     5761 gaacagtgaa tatatcgaaa aaaaagattc tcagatagat agagtggaaa tagaaaaaat
     5821 tatcatagga gaatctaatg ataataggga attaagatca tctgaagata ttctattaga
     5881 aaaaaaaata aaaaaaataa ttaaaaactt ctataaattg tcctctaata atatacatat
     5941 tactatagag acatgttaac tgtttttaca ctttgttttt aacctagaag cacaggagga
     6001 taaagatgaa attggatttt tttacaaaag gtaataagac cgaaaaagat aaaaaaagaa
     6061 taagctttct cttcattatg tttttgacag gattattgct tttattattt tcaaaaaatc
     6121 ttataaaacc aagcaataat accaaggtag ataatagtat catcgcacct aatacatata
     6181 aggcaagtga tccccaaacg tatgaagaaa aacttgaaaa aagacttgag aaggaatttg
     6241 ctaatattga tggagtgggt aaagttgaag taataatcat gttaaaaaca agcggtgaaa
     6301 taattataaa taaagatacc cctaattcac aaacacaatc cgatgaagta gatagcgaag
     6361 gtggaacaag acaaaatata caaacagatt ctagagaagc cactgtactt attaataact
     6421 ccgatggttc tactaaacca atcatattaa aagagcttga accagagatt agtggcgttg
     6481 taataatagc tgaaggcggt gatgatatac ttgttaaaaa aaacttaatt aatgcggcta
     6541 aagtattatt agacgttcct atgcataaaa tagaagtaat gaaaatggtt caaaataagg
     6601 gggaataatt atgcaaactt tcaaaaagaa tcaaattata attactgctt tggttattat
     6661 gattgcgata gctggatatc ttcagtttac agaaaatgat ggtactccta cacaagaagt
     6721 tctgaataat caaagtgaag atcaaaaaaa agataacgtt acaacaccaa cagcattagt
     6781 accaaatggt gaaaatgcca atactgatgc aaaaactgaa gaaaatgcag cagatgatgt
     6841 atcagaaaat caatcaccta atagtattgc aaaacaacct gagcaaaaac aggaacaaaa
     6901 acaagaacag aaacaaggag agaacaaagc ggctgagcct gcttcaacag ttccagaaaa
     6961 tgaaaacaag gaagaaaaaa aagaagaagc gaaagaaact tctagtgata aaaatgatag
     7021 taatgtagga gaagctatcc taacaagcgg caatacatta caagcaggat atttcttaca
     7081 aaagaaaata gatagggagc aggattattc aaaattaaaa gaaggttatt tatcaataat
     7141 tgacaatcaa aatctgaaag atgaaaataa agtggaagca gtaaaagaaa tgattgacct
     7201 tcaagataga attgaaaaag aagctgctgc tgagtccata ttagaagcta aaggattcaa
     7261 ggatgtattt gtaagaatga ttgataataa agttgatgta gtaatcaatg caaaagaatt
     7321 atcacaagca gatcttgcaa aggtagaaga tgtagtaaga agacaaacag gagttgacgc
     7381 agaaaacatt gtaataacat tattggatgt tactaaagca caataaacat atatagaaat
     7441 gatattaggc ttttatgtaa ggattactat tacatgaaag cctaaaatta ttagaaaaaa
     7501 taatttgcaa aacctataag atttgttata attaacctag aaatggtttt attaaaaata
     7561 gcatgaatga attcatataa taaaatatag ctgagatagg aggattaatt aatggataga
     7621 cagacagtta aaatacacga aaaagataaa gtcggagaag tccatattgc agatgaagtt
     7681 attgctataa tcgctgggtt agcagctaca gaagtagagg gagttgctgg tatggtaggt
     7741 aattttactg gcgatttagt tgagatgctt ggtaaaaaga acttggcaaa aggtgtttta
     7801 gttgatgtag gagaaaaaga tgtttcactt gaactctcat tgatcgttga ctttggaagt
     7861 agtattccag aagtaactaa caacgttcaa gaaaaagtta agaatgcagt agagaccatg
     7921 acaggacttg aagttgatga aattaacata agagtagctg gtgttaacgt agaaaaaagc
     7981 aaatagatat ggattataac cactaaatta ggctataact gtaatttttt aaatatttgc
     8041 ttgtacaatt aactaaatat agtataataa agataccctt aaatatttat atttaagggt
     8101 attaaaatgt aataaaaata tttattcaat atatatttaa tcccaggagg tacattatga
     8161 acagaaggat catgagagag catattttta aactagtatt tgctattgaa tttgatgaag
     8221 aagaaagatt tactgataga gtaggagtat atcttgacga gcttgaaaca agcgatactg
     8281 ctaaagaata tataaaacat aaagctatat ctatatttga aaaattagaa tctatagatg
     8341 aaatgatcaa taagaatgct gagaaatggt ccataagcag aatgtccaaa gtagatgtaa
     8401 gtattctaag agttgctatc tatgaaataa aatttgacga agatatccct actaatgtag
     8461 caataaacga agcaatagaa attgctaaga aatatggtgg ggaccattca ccatcatttg
     8521 tcaatggaat acttgccaaa gttgtaaatt aatcggggtg atataaatga aaaaaagtat
     8581 tttttcagta tcacaggtaa atgcctatat aaagaaaata tttgtgaatg attatgtcat
     8641 caatgatatt tggataaaag gtgaagtctc caactgcaaa atacatcgtt caggacatgt
     8701 atattttact ttgaaagata ataatagtgc aatatcctgt gttgtattca agaactatcg
     8761 tgattttgta gaatgtgagt taagagatgg aattaacatt actgccagag gttatatttc
     8821 agtatatgaa agagcaggga cattccagct ttatgtacaa cagataaaat cagatggtat
     8881 gggagatttg tataagaaat ttgagatatt aaaagagaat ctccagataa aaggatattt
     8941 tgattcggat aataaaaaga agatccctag atatccaaga agagtaggca tagtaacttc
     9001 agatacggga gcagctgttc gtgatataat caatgtatca aaacgaagaa atccatatat
     9061 aggacttgtg ttatacccat cccttgttca aggagaggga gcggcaaata atattgtaaa
     9121 aggtataaaa tatcttgata gggttactga tgttgatgtc atcattattg gtagaggtgg
     9181 aggttccata gaggatttat gggcttttaa tgaagagata gtcgcaaaag ctatttatga
     9241 agctaatact ccaataatat cggctgtagg acacgaaaca gattttacaa tatcagattt
     9301 tacttctgac cttagagcac caaccccttc agcagcagct gaacttgcta tcccagcttt
     9361 tgatgaaata gatggtatat tagaaaaata caattataag cttactaata gcatgaataa
     9421 caagattgaa tcctgtataa aagctattca actaaataaa ataaagcttg actttaatag
     9481 tccatcaatg agagtattaa aggaaagaca atatataaca gaatttgaag atagattaaa
     9541 tagaagaatc aaggaattga ttaatgataa taaaaactat gtaagtctgt tacaaaacaa
     9601 attaagtgtg ttatctccaa taaccaattt ggaaaaaggt tattcttata tagaaaatac
     9661 tcatggacag gttaaaagta taacggatgt caatatggga gagactctat taatacaatt
     9721 gcatgatgga aaaatagagg ctgaagtcaa gaatatagaa agtggaaagt ggggtagtca
     9781 tgagtaataa attaactttt caagagaatt tggacagcct ggaaaaaata gttgaacgat
     9841 tggagtcagg agaaacaact cttgaagaaa gtctagaact atataaacaa ggcatgatgt
     9901 ttttaaaaga atgtaatagc aagattgata aagtagaaaa agaaatagaa gttgtacaaa
     9961 acgaaaacta agtattgtgt aatgttattt acggaaggaa atgaacagag taatgaattt
    10021 tagtaatgag ctaaaagata aacagcaagt agtagaaaag atattattga aatatatgcc
    10081 agaaaatgct tcaccatatg accatgttgt ctataatgcg atgaagtaca gtctaatggc
    10141 aaatggaaag agaatacgcc ctatattaat gatggagtca tataaaatat gcggcggtaa
    10201 caatataaga gagatagaag catttatggc ggctatggaa atgattcaca catattcttt
    10261 gattcatgat gatttacctg ctatggataa tgatgattat agaagaggta tattgacttg
    10321 tcataaaaaa tatggtgaag atatagcgat tctagctgga gacggtcttc ttaatagtgc
    10381 ctacgaaata atgattgatg cttgcttaaa ggataataag gtcaaagcta agcaaaaatt
    10441 aacagcttgt aaagaaatag gaaaagccgc aggagtaaaa ggaatgattg gtggacaagt
    10501 agcggatgtc atacaaaatg atatcactat ggacgttatc aactatattc atatccataa
    10561 aacttctgct ataatagaag cttctctcac tgctggagca gtacttgcta atggtagtat
    10621 gcaaaaagta gagactttca gaaagattgg tagatgtatt ggattagcat tccagattca
    10681 agatgatata ctggatattg ttagtacaac agaagaacta ggaaaacaag ttggtagtga
    10741 taataagaat ggtaaaaata cttatgtaac tataaaaggt attgaagaat caaggcagat
    10801 agttaatgaa ttaattgaaa aagccttaga tagtttaaat agttttgata gcagtgaaaa
    10861 agaatttttg gaagaattta ttttttatct gagaaacaga aaaaaatgag gtgtatttag
    10921 tggagaactt ttatactatt acggagaata gagttttatt agctgcagtt attgcttggt
    10981 ttgtttcaca gggtattaaa ttctttacat gtctaataaa aacaaggaaa attagaatgg
    11041 atagaattat gggttctggg ggtatgccta gttctcatac agcctcagtc atggcagcta
    11101 ctttctcagt tggtgaatta ttaggatata ataatcctgt attcggagga ttgatgataa
    11161 tatcttttat agtaatgtat gatgctgctg gagtcagaat ggcagcaggt aagcaagcaa
    11221 gagcaatcaa taacattgtt gaagccttag ggtcttatag attaaagatt gatggacagt
    11281 taaaagaatt gcttggacat acatatatgg aagtattagt tggagctgct ttaggtattg
    11341 taatagctct tttaatcaat taaatttgaa tataaatggt aataaatgtt aaaataaaat
    11401 tatagatttg taaatttgtt aattaatgat acttgattta tttttaaata tgatatatta
    11461 ttggatatac taaagatgca gtatcctagt tggtaccatt aatctcgaag acgggcctaa
    11521 aaatccgtaa aagggcatat cgatgaagtt cctggtgttg gctggtgacg cccagtcgcg
    11581 ggcttatgct gggagttaag acataagggc gatccacaat ggcatgtggg cgtggaccct
    11641 tttgtcgtgg agacctgcgt atgtggaaac tgttagatac agttatctac ggcgcgggag
    11701 taaacctgtc atgcggcgaa agctgtggac agagtagcct gccttgcgtg aaataaaggg
    11761 aatagtaatt taagagcaaa acttttggcc aaaagtgaag cagatattgt tacttgaaac
    11821 tttttttcgc taaagaggct agggattaaa tggtatcact gaggaaaact cctaggctgt
    11881 tcattttttg aagcttattt aggattacag tgtggttgta aggtgatcta gcgctactta
    11941 tggtgacata gtaggaatta atttaatggg gaaccacttt tttggcgaca aaaaagtatt
    12001 aattcgggaa aacctgctgg actataagcc gcaaaattta ctaaatttgc tatctttagt
    12061 attaattcat gttaatacta aattacataa taaaatattt cataagaaaa atcgaggtat
    12121 aataatttga gtaaaaataa aactaaagta aagtttagga gtttatatac acataaaaaa
    12181 ataaatactc tttggattgg gataataaca gtcattacgt taataacagc catattactt
    12241 ggatatattg cactagtact tatggacaat gtaagcctat acggtgctat ttttattgta
    12301 ttagtaatag tattgttagg tatatttttt gatttgctag gtattgcggt tactgcagca
    12361 gaagagacgc cgtttcattc aatggctgca agtaaggtaa gagggtctaa agaaagtata
    12421 actattatta gaaatgctgg agctgtagct aatttcttta atgatgtaat tggagatata
    12481 tctggtatta tatcaggact cgccactgga gtcattgttc tcaaactagt agctaaattt
    12541 gctatacaag atacaatcat taatgtactt cttactggag tgattgctgc tattacagta
    12601 gggggtaaag ctataggtaa agaaattgca ctaaggcact ctaacttgat agtttataaa
    12661 ttaggtgtaa tttatagcct gttcaggaag caaaacaaga acaaataaat taaagataag
    12721 taaaggtgtt gaaaaaagtg aacgaaatat tagatgggat tagtagccct agtgatatta
    12781 aagctttaga aatagaccaa ttgaacatac tagcaaaaga acttagagaa tatctaataa
    12841 aagtagtaag taatacaggt ggacatttaa gttcaaattt aggagtagta gaattaacat
    12901 tagcacttca ttattgcttt aattcaccat atgataaatt aatatgggat gtaggacatc
    12961 agacttatat ccataagatg attactggta gaaaagaaga gattaagact gttagaaaat
    13021 ttcaaggatt aagtggattc ccaaaaagag cagaaagcga acatgatata tttgaaacag
    13081 ggcatagctc aacatccatt tcagctgccc ttggttttgc aaaagctaga gaattattga
    13141 atgagaataa ttatgtggta cctataatag gtgatggatc aatgacaggt ggaatggctt
    13201 ttgaagcatt gaataatgct ggaaggctag attctaattt tattgtgata ctcaatgata
    13261 atcaaatgtc tatttccaga aacgtaggtg ggttatcatc ttatttagat acaataagaa
    13321 caggtacagt atataaagaa atgaaagaag aagttgagaa agcacttact aaaattccta
    13381 gaataggtaa ggaagttgtt aaggttataa gagacgtcaa atctggtatc aaacagttgg
    13441 tcatacctgg aatgctattt gaagaattag gatttactta tctaggtcca atagatggac
    13501 ataacatatc tgcattaata aaaacactca atcaagctaa aagactaaat gagccagtgc
    13561 tcatacatgt taatacaata aaaggtaaag gttataagcc ggcagaactg aatcctacca
    13621 aatatcatgg aaccaaacca ttctatatta agaatggcag acctaagaat ttgccttgtt
    13681 cggataccta ttcaaaagta cttggtgata ctcttattga tatagcagat aataagaaga
    13741 aaggtatagt agcaatatca gctgcgatgc cagaaggtac aggtcttgat aaattcgcaa
    13801 gaaaatatcc tgataaattc attgatgttg ggatagctga acaacatgct gtaacttatg
    13861 ctgcaggact tgcagctagt ggcattaaac ctgtagtagc tttatactca tcattcttac
    13921 agagagctta tgaccagatt atacatgatg tctgtatgca gcgcctacca gtagtatttg
    13981 caattgatag agcaggtttg gtaggtgagg atggtgaaac ccatcaaggt atatttgaca
    14041 tatcattttt gagccatatg cccaatatga cagtgattgc tcctaaaaat aaaagtgaat
    14101 tacaatctat gattaaattc gctgtagact atgaagcacc tatagccata agatatccta
    14161 aaggtaaagc ttcaaatgaa ttaaaagaat ataatgaaga aattacttat ggaaaaagtg
    14221 agatcattaa aagaggcagt aaaatagcaa ttatcggtgt tggaaccttg acacagacag
    14281 catacaacgt ttctgctatg ctagaagaga ataatattat gtgtacactg attaatgcta
    14341 gatttgttaa gcctattgat aaagaattaa ttgaagagat tgcaaataac catgattata
    14401 tattcactat cgaggaaaat gttgtttctg gtggatatgg gaataatgtt gtaaaatttg
    14461 tatctgatac ccaagctaat acaaaagttg tttgtatagg tattgaagat gattttatac
    14521 aacatggtaa aagagatgaa ttaataaaat tatgtaagtt agatgaagaa agtatatata
    14581 atagaattat gacatacgta aacaagtaaa atatatacac taagaatttg ctttaacgga
    14641 aggaatgtat ataattatgg tacaaaaaga aagacttgat atattactgt tcaataaggg
    14701 tctagctgat tcaagagaaa aggcaaaatc aattattatg actggaaatg ttttcgtaaa
    14761 tggtgaaaga gaagataaac caggtaccaa atttgatatt aagtcggaaa taattgtaaa
    14821 gaagaaccct aatccatatg taagtcgtgg aggattaaag ttagataaag ccgtaaaaga
    14881 atttggcttg aaattagaga acaaagtatg tactgatgtg ggagcttcca caggtggatt
    14941 cactgattgt atgcttcaaa atggtgcaaa gaaagtatat tcaattgatg ttggatatgg
    15001 acaattcgct tggaaattaa gacaggatga acgagttgta tgcatggaaa aaaccaatgt
    15061 tcgttatgtc acaaaagata tggtggatga cgaaatagat tttgtttcca tagatgtttc
    15121 ttttatatct ttaaccaaag tattggaacc tgttaaaaaa ttgatgagtg agaatagtga
    15181 gatggtttgc cttataaaac cacaatttga agcgggaaga gagaaagttg gtaaaaaagg
    15241 tgttgtaagg gatagagctg ttcacgaaga agttattgag aaaattatga aatatgtttt
    15301 gtcaatagat ttctccataa aagatttaag tttttctcca ataaaaggtc cagaaggaaa
    15361 tatagagtat ttactttacc tgactactga aggacaatca acaatggatg atgaagaaat
    15421 tattagtatt gtgaaaacag tagttgataa agctcacgaa aaattataaa atataaatgt
    15481 gccattattt aggaaatgaa catgagattc ttatagaatt ctgtaaaata agtatttcct
    15541 gaattataga aggatggttt tatgaataaa tttgtaataa tacctaatct gaccaaggat
    15601 aaaaaactag aaacaacaaa gttaattgtt gattggttag aaaaaaatga ctgtaagata
    15661 tgtttgccag cacaaatagc taattatatc aataagcagc aatatagctg ttcagaaagt
    15721 gacatgtata ataatgctga ttgtgctatt gtattaggag gagacggaac gattcttaat
    15781 gcagcgagaa atctgatcaa atatgatttg cctatacttg gtgttaatct aggtaatcta
    15841 ggttttttgg ctgaggtaga aaaaaaagat gcattaagta ctttgtcaaa gatcattaaa
    15901 ggtgattatt atgtccaaag aagaatgatg ttggatgtaa aaagattaat taatgataaa
    15961 gaagatttaa taggagttgc attaaatgac attgtaatag ctagaacgtc tatatctaga
    16021 atgatgaaat acagtattta tgttaatgat ggacatgtta acaattattc tgcagacggt
    16081 ataatagttt ccacgcctac aggctcaaca gcatataatt tgtctgctgg aggtcctata
    16141 ttggacccta agaatgaaat gatggtcata acacctatat gccctcatac attgatgtca
    16201 agaagtattg tactttcaaa aaacgatgta gttaagatat cactagaaaa caacagaaag
    16261 agctggaatg acgatactat gattaccatt gatggtcaag agagttttaa catagaccaa
    16321 aaagataaaa ttataatatc taactcttat aaaagtgcta aactaattac atgtaataaa
    16381 aatggatttt atacgattct aaaaaagaaa ttaggtaatt gctaacttta gacagctatt
    16441 atagattcat cttatattta tagggaaggt attcctaatt attaatgaac taggaggaaa
    16501 atggatgaaa attgaacgcc aaactaagat tcttcaatta attaatcact atgatattga
    16561 gactcaggaa gatttagcaa gtagacttat cgaggaaggg tttatagtaa ctcaagcaac
    16621 tatatcaaga gatatcagag aattaagatt gactaagatt gctacatcag atggaaaaca
    16681 gaaatacgtt gtattaaaga ataaagagac caaattaaat gaaaaattca taagagtatt
    16741 caaagatggt ttttcatcta tggaccgggc aggtaacatt attgttttga agacattagt
    16801 tggtatggct atggctgtag ctgctgctat tgatgcactc aattttgatg acatagtggg
    16861 ttgtatagct ggggatgata ctattttctg tgcagtaaga acagaaaacg atgccattag
    16921 gattatggaa aaaatgaaca aattggttaa taataattta tagattccat tgaatacgat
    16981 actattatac tttctatcaa gtaggaggaa attaatatgt taatacacct tcatgtaaaa
    17041 aattatgcgt taattgatga aatcaacgta gattttgatg ataacctaaa tatattaact
    17101 ggtgagacag gagcagggaa atccattatt attggttcta ttaatgctgt tcttggtggt
    17161 aaagtcagta aggatatgat aaggactggt tgcgatagcg cattaattga acttttgttc
    17221 tatgtggata ataatgttgt tttaagcaaa ttacatgaat acgatattaa catggataat
    17281 aacaaagaac tcctaataac caggaaaata aatattaatg gtagaagtgt ctttagaatg
    17341 aatggacaag ttgttactac atccatagta aaggatattt ctactaagct tattgatata
    17401 catggccaac atgaacatca atctttacta aataagaaga atcatctttc attattagat
    17461 actttttgcg gtgtagatgt tttagagtta aaagaaaaac tcagggaaaa gtatgcttat
    17521 tacatggaac tcagtagtaa gatcgatcat ttcatgcttg atgaacacac tagaaaaaaa
    17581 gaaatatctt ttttggaata tgaaataaat gagataacat cagctaacct gataattggt
    17641 gaagatgaga aactcaagga agaatacact ttactctcaa atggtaaaaa gattattaag
    17701 tccatgtcag aaatacatac ttatgttaat ggagacagta ccaatatgac aggtgcaata
    17761 gaccagattg ggcaagctgt aaggctactg tctggaataa aaacactgga taaaaatata
    17821 atgaacatgg aagaacagat ttcaaacatt gagattatgt taagtgattt caatagagat
    17881 ataaacgact atataagtag ttttgaactg gatgaatcaa gatattttga gattgaagat
    17941 cgaatagatt taattaataa tttaaaaatg aaatatggag atactataga agagatatta
    18001 aaatataaag aagaaaaaga aaaatatcta gaagaattaa tcaatcatga agaacatttg
    18061 aatcagataa ataaagaaat aaacacacta aaaaatgaaa ttgaagttta ttgtggtgac
    18121 ttaacaagaa ttagaaaaga aaaagctaaa catatcagta aactgattgt aaatgcatta
    18181 aggcacatta atctgttgaa cactaatttt attattgaag tcaacagagc taacaaattt
    18241 aattcaaatg gatgggatga aattgagttt ttaatttcaa ctaatgtggg agaaccatta
    18301 aaatcactta gtaaagtagc atcaggagga gagttgtcaa gaattatgct ggctatcaaa
    18361 tcagttctag ctggtagtga cgatattgaa tcattgattt ttgatgaaat cgatactggt
    18421 attagtggaa aaactgcagg actggttgca gaaaaacttg tacagatttc aaaagaacat
    18481 caagtcatct gtataaccca tttggctcaa atagctgcta tgggagatgc tcacttcatt
    18541 attcagaaga aagttaaaga taatgttaca catactttaa taaataaatt agataaagaa
    18601 agttctatca atgaattagc aagactgctt ggcggcataa aaataactga tgctgttatt
    18661 gcaaatgcaa aagaaatgaa ggactacgca gaagaagtta aaaaaattca ataaaaagtt
    18721 taaaaaggtt tagttcaact tacataataa ataaaaactc attattatac ataacctaat
    18781 caagaatcta attcttgatt ttttcatgtt tatacgttat tacagcatat ttgtataaag
    18841 aatgattatt attaagagaa attctggttt atttgtatag tcaataattt catatattga
    18901 ttctatttac tagcataata aaatttgcgt aagggaattt taatagtaca caaataatga
    18961 gaagtattaa aatccccaaa agaatagtaa ataggatgtg aaataatgag aagcaaagga
    19021 tacagattta gaatttttct attttttagt ctattagtca ttttagtaat taatgttgga
    19081 tcagatctac ttataagcag atatttacca ggtgaaatca aaattttagt taacgaagaa
    19141 cgcgacttcc tatttaatgt tccattagac gctaagataa atggaaatct tgaaggcgtt
    19201 gtaatggtta atcaggaacc tgtcaaagat aatcttgtac tcaatctaca aaaatctttt
    19261 acaattaaac ctaaaaaaac aggtgttatt gatgtagaac taaaattatt tggtatattg
    19321 cctataaaaa cagtaaaagt tgatgtaata gataaaaaaa gggttgttcc agtaggtaaa
    19381 accataggtg ttacagtata tacagatgga attttagtac ttggaactgg tttggtatat
    19441 ggtgaagacg gaaaaaagta taatcccgca aaaggaaaac tatatactgg tgattatatc
    19501 aaagcagtaa aaggaaaaca aatatcaaga aaaaaagaat taatagagat tgtaaagaaa
    19561 aatcagggtg aacaaataga actagatgtc ataagaaatg ataaaaaaca aaaagttaac
    19621 ataactcctg ttaaaaccat agaaaataat caatataaaa tcggagtttg ggttcgagat
    19681 gatactcaag gaattggaac aatgacttat atggatttgg ataaaaaaac tttcggggca
    19741 ttaggacatg gtataacaga tgttgacaca aagcaactaa tagaaattga gactggtgaa
    19801 gtcgttaata caatgattac aacaattaaa aaaggtgaag atggagtgcc tggagagata
    19861 tctggaatca tagttggcgg tgaaggaaat cgcttaggag agataaagaa gaatacctct
    19921 cacggtatat ttggagaagc atccaatgaa ggaatagacc aagttctaga gaatgatata
    19981 atacccatag gttttagata tgatgtgcat gaaggtcaag cctttatcag aagcgatgtt
    20041 agcggtaaat taaaggatta cgagatattg attaaaaaga tatatttagg tgatgagtct
    20101 aataaaggta tgattattga agttgttgat gaagatttga taaaaacaac aaatggaatt
    20161 atccaaggaa tgagtggaag tcccattatt caagataata aattaatagg tgcagtcaca
    20221 catgtttttg ttcaagattc aaaaaagggt tatggtgttt ttatagaaaa tatgttaatt
    20281 gaggagtaat atataaagag aatatgtatc ttgtgcatgt cgaatcttgc gaatattatt
    20341 tattgaatta atatatagtt agtattataa ttataacatg tcatatggta acgtattctc
    20401 tatataaatg aataaacagg atatcataag ataataatat ggaacgtaat atcgtttcaa
    20461 ggaagagaag ggggaaaaag gttgagcgat acaatcaaag tcttaatttc agatgatagc
    20521 gtaaaaatgt gcactatctt atctgaatat ttaaactcaa aagaagatat cactgtagtt
    20581 ggagttgcta ataatggtga agatgcatgt aaacaaataa aggaaaaaga acctgatgtt
    20641 gttttacttg acattattat gccacaacta gacgggctgg gagtattaga gagaatgtac
    20701 gaagataagg acataaagaa agttcctatg tttattatgt tgacagcagt aggacaagaa
    20761 aaaataacat ctagtgcact taatcttgga gcggaatatt atataatgaa accttttgat
    20821 aatgagacaa tcgttaagag aataagacaa ttaaaaggta aaatgcagtt aattaaacgt
    20881 gatagaagaa atgattttgt ttctgaaact gaaaaaggtt attcagcaag aagtttagaa
    20941 gctgaagtaa ccaatataat tcatgaaatt ggagttccag cacatattaa aggttatcaa
    21001 tacctaagag atgctataat aatggctatt aatgatatgg acatacttaa ttccataact
    21061 aaattactat atccatctat agcaaagaaa ttcaatacaa cacctagcag agttgagagg
    21121 gctatcagac atgcaataga agtagcatgg ggaagaggta agatggatac catagataaa
    21181 ttgtttggat acacaataaa tcatggtaaa ggtaaaccaa ctaattcgga atttatagct
    21241 ctaattgcgg acaagttgag attagagctt agagtaggat aaatttgaat tataagatgt
    21301 atataatttt gatttatgga taaaataaat attgtgaagt taatgattaa tttcactaac
    21361 tttacgctga cttataagtg aggtgttaga gccaatgtac atttaataga agttattaac
    21421 gtaactgttt tagatgtaat gaggtaatca gcatttataa gtaataaagc tagtaatcgt
    21481 aacagattac tagcttttta atacctaact aactagttga caataaccta aattatggag
    21541 ggctataatg gctaaagaaa aagtaaaaga caaaggtgga agtcttggtg gactatctaa
    21601 aagttataac aataatagga gtgtgaatgg taaaataaaa aattctaagg ataccacaag
    21661 ccgtaattca gataacttga gccataaaga ttaaattatt taatattttt tggtattttt
    21721 attgacacta gtgactataa tattatataa ttgttttagt cattagtgtc cataataatt
    21781 acttacataa tttttaggtc aaagaaagga aatgattatg cctaaaatag ttgatacaga
    21841 agctataaga atagagataa ttaaaaaagc atttgatgtt tttgttaaga agggctatta
    21901 caaatcaagt atgacggata ttaccaagag ttgtaatatg aagcgaacaa ccatttatca
    21961 ctattttaaa aataaggatg agatatttga acaaactgta ttatacgtta tagaaactct
    22021 tgaaaatgat attatagata tttctaatga tgatgatatg actctaatga aaaaaataaa
    22081 atatctaact aataaatggg ataatgaatt tagtaataac aatattctat tactacttgt
    22141 tgaaatgtgg tttgccataa agagagaaga aggagaatta tttgatagaa tcaaaaaaag
    22201 aataaccttg atgaataaat ctatcaataa aattgtggta caaaaagcaa aatatatggt
    22261 taattctaag agagataaaa agcagttgat tgaatactca atgataatgt ccatacttaa
    22321 tcaggtttcc cttgaaaaag gatttttgag tgaaagtata atctctgtta tatcatcttt
    22381 ttaaattaat ttacatgttt agtaataatt tatacaagtt ttatatatat tatagtaaag
    22441 tgtaaaatat tacatatata agcctattta aataatttaa ccttgttggt aaaagggagt
    22501 agcttcaaag ttataaagtc aacaaccgcg gtatataata cctggcttta tagtcctgta
    22561 atggaaagca agacttttat gacaaaatgt agataactag tctgcaattg tcataaaagt
    22621 ctttttaaat tatataagat aaattaaagg aggtcatttt ttatgaaatc accaaaatca
    22681 ttttttagta aagtagctat aaaagaaggt ataaaatatt tagaaaaaga tcctataacc
    22741 aattttccaa agcttattga ttgggcaggt aagattccta tgttaccaag ccaaagacac
    22801 cagtatgagg caataattga tatgtggcag gataaggact ccatatggca cggttttata
    22861 gaaagaatat tgacaaagat acatcccaat attagaaaga cacttttaat gaattttact
    22921 atcaatgctg gaattgaagg acttaaacta attgatgcca acaaagaaaa atatgactgt
    22981 aacatacctt gggcaattct aatggatcca acttctgcat gtaacttaaa atgtattggc
    23041 tgttgggctg cagaatacaa gaaaaatgat tcattagact atgatacctt gagtaacata
    23101 ataaaacaag gtaaagaatt aggtacatat atgtatattt actctggtgg cgaacctatg
    23161 gttagacgag atgatataat aaaacttgca agagaacata atgattgtgt attcttggca
    23221 tttactaatg gtactctttt tgacgaagat tacgcaaaaa aacttcagga agtcgggaat
    23281 gtcacatttg ctataagtat tgagggatat gaagaacaaa cagatatgag aagaggaaaa
    23341 ggtacatatc agaaagtaat caaaggaatg gatatattaa gggaacatgg tattcctttt
    23401 ggattttcat catgctatca taacaaaaat gaagagatag tatcttcaga agaatacata
    23461 gattttatga ttgaaaaagg ttgctatttt ggatggatat tcacttatat gccattagga
    23521 aaagatgcag tacttgacct attagcaaca gctgaacaaa ggaaagatat gtactataaa
    23581 gtacgtgaat atagaaaaac aaaaccaata tttactatgg atttctggaa tgatggagaa
    23641 tatgtcaatg gatgtattgc tggaggaaga aattatcttc atatcaatgc aaatggtgat
    23701 gttgaacctt gcgcattcat tcattattca aatgcaaata taaaagaagt aagcttatta
    23761 gatgcattaa ggcaaccttt attcagacag tatagaaaac atcaaccctt caatgataac
    23821 atgcttagac cttgtccatt acttgataat ccagaaatgc ttaaaaagat ggtacatgag
    23881 tcaggagctc tttcaacaca gccaatggat agagaggatg tagatgaact tacaaccaaa
    23941 accaaggaag ctgcagaaaa atgggcacct gtagcagaag aactttggga agaatcacat
    24001 ggatgtatta attgtaaagc tgctaaccaa taatataata aaactatagc tttttctata
    24061 cattttggga ggatggcact ttgaaacgag acaggcgaat caatgcatta ttactatttt
    24121 taaaattatt ttctgttttt aatgttgtgg tcatagctat tattataagc cactattggg
    24181 gaaaaattac accagaagat atttttaact atgttcctga taattacttt ttagctgcta
    24241 ttactatcat agggttattc ttgattaaat cacttagtgt ggtattacct ttgatggctc
    24301 tttatattag ttcaggaatg atattttcgc cgttgtgggg tattattgtt aatctgatcg
    24361 gattgtttgt cagtttgaca ataccttatc tgttaggtag attttgtgga aaaggtttat
    24421 tggatagatt attagtgaaa tataaaaaca tagagaagct taggacaatt aagagtaaga
    24481 atgaatggtt tttatcatat atactgcgga tgattggtat tctgccagga gatatagtta
    24541 gtatgtccct aggagctatg aatattaatt acaataaata tattgtgggt tcaatagtgg
    24601 gattattccc tagaatggta gcagctacat gtctaggttc aaccataaca gatcctactt
    24661 caccagtgtt catactgtca tgcctaatta cagttgtgct gactgtaggc tcaatgttct
    24721 tgcatcagag atatatgaaa aaagaagatg aaagaaataa tgttgaagta atgactagat
    24781 aataatttaa caaaaaagga gtttaacttg ataagataat taagtttgct cctttttgta
    24841 ttacctaatt ataacaaaat aactaaatta agtataaaaa ttctctttat gataattaat
    24901 aattgtgtta atattaagag taatgagtat taaaaaaata atatattcca aacatctttt
    24961 ggcaagtaac gagtattggg ggaatataga tgcaagataa tttttattat agtgaggaaa
    25021 aactattatt tgataacgaa gtaaaagtaa actatcgtat agcaaaagtt ctattctaca
    25081 ttgctgtgac agttattcca ttagtgatag ttctacaatt acttggagtg ttcatatatt
    25141 acatggttga tgcaataatg gcaatagtaa ctgcttttat tctcttaatc atgcctagaa
    25201 tactaacaat agtacatgta cataaaaaga agtggttcaa gtatatactg ttatttttag
    25261 ttataatgat gttgccattg atttatttag aatatgatta tatggtattg attttatgga
    25321 tatttccatt attgataagc tgtatgtatt tttctaacag gcttaatacc attacggtaa
    25381 tttttgatgt agttgtgtta ggttttacaa gttattatag atcctatcaa agattacaaa
    25441 acaatttgat ctctcagcgt atcggaggat tgttcaaaga ttttattata agctatataa
    25501 cttatgcgat gctagtcatg atatcatatg tcataatata tttactgact aagaaaacca
    25561 atgagctatt acaggatgct ataaaaaaga aggaattcga aattctttca ataactgatt
    25621 caatgacagg aatatataat tatagatatt tgatgagtga attagaaaaa aatcaggaac
    25681 tgtttcataa ggagaatatt ccatttgcag ctgttctttt tgatgtggac cattttaaaa
    25741 gcatcaatga tacatatggt catgttgaag gtgattgtgc attgcaggcg atagttaaat
    25801 gtttgcagaa tatggtaagg gaaaatgatg taataggtag atacggtgga gaagaattca
    25861 tggttatcct atctgacact acagttaatg aagcatatat gatagctgaa aaatgtagac
    25921 aagcaatatc tagattaaag atagaaaatc ttgatacata tatttcaata agtggtggtg
    25981 tggctgaata taatggagaa aacataaaag attatattag gagcatggat gagaaaatgt
    26041 atgatgccaa gaacaatgga agaaatataa taatagcata gacttctata agcttaagtg
    26101 aatattatat aatgtaaaac actggtgtta tggtaattca ttagtgtttt tttatatata
    26161 aaaagtggtt ttataaattg ttaactttag taattaatgg tataatgtta taggtcttat
    26221 ttgtctgctt agatagtaag attattgata atatactaaa atgataagat aaaaatagga
    26281 gataaaaatg aagtttaaca aaaaattatt gaatatacca attgttttaa tgatagtcat
    26341 tgcagtactt tgcttattga atgttccgtc aagaattaat atgctgaatg gaatttcagg
    26401 tgcagaaaaa ataggtataa ttaatataaa ctataatact gaacaacaaa aaaatgaata
    26461 tggtgaagag atttttgtta cagataagca gaaattattt aatatcatca ataccatcaa
    26521 taacggtaaa atcgatacag aagctactcc agacaggggt ggggcaaatt atgaattaag
    26581 attttataag gatggtaaaa gtatcaaagc agattattgg cagaatgaaa aatataatct
    26641 aagtgttgaa ggggttgagg gagaaatagt cgttgataaa aagttggaac aaattataga
    26701 aacaataatt caagaaaata gtaatgagta agttggtttt tgttatggag ggaaagtgta
    26761 aatgaaaaag acaactacta tagttagttt attatttgct atcatgctga tgacatcaaa
    26821 tgtttttgct gggaatactg atacactaca aaataatttt gaagagagtg aggatatata
    26881 tattgaacta agtgaaccta ttcttttaaa agctcgacaa tatgtagacg gacttatgaa
    26941 tgctcatttc gaccaggtat ttgcttattc taatgaggga tttatgctgt gtttatatga
    27001 aactctttat gaagattcgg ataaatactt aaatgaaggc aaagttgtta gtagtgaagg
    27061 tgaacagatt ccattttggg atccacatca ggagagaatg cttagaattg ataggttagt
    27121 taaagatggt tatataatgg aagatgagct tactatagaa atagatagaa cagtgatagc
    27181 ttcaatactt tatcgtattt ataaggataa aatacccttc aaaggttctg ttgattatcc
    27241 ggataccgaa gatatagctc ttagatgggc aggtgaagtt ggattaccaa cgtttgcagt
    27301 taatacagga ttgaagatta agcctgagga ttctattaag agtgataaaa attttagcct
    27361 tttatactat ccaaatgatt atctgaaaat cattacttat gcgtacttaa tgtttcctaa
    27421 tccttattct ggtaattatg tggacttaga attcattaag gaagatgtta atgatataaa
    27481 agctaaaaaa attaaggaat taattatgct gacaaggaaa gaagtaatga aacccagatt
    27541 aggagatttt cgacgtgatg tgttgaataa tgagaatata ggaaatatag ttgattctta
    27601 tcaaaaaact aagtcatatg aaactctcaa gaaaatatat caaattataa aagacagttt
    27661 taatctattt gaatatcaag ataatattgg ttacttaagc tacaaattta gtgtatgtaa
    27721 ataaatcaaa tatattatct tatgaaaaat tgttcttagt atctatttat aaattagcat
    27781 gtaataatat ttggaggaaa aaatgacaag attatactta acaagacatg gagaaactga
    27841 atggaatcta attaaaaaag ttcaaggcag tagagattcc aatttaacac agaaaggcat
    27901 tatacaagca acaaaactag gtaaatatct agagaatact aatattgacg tgatttattc
    27961 aagttccagt ggtagagcct ataatactgc aaaaataata gctggtaata ggaatataga
    28021 agtaattaag atggatgact tgaaggaaat gaacctgggt atttgggaag gtaaaacttt
    28081 tgaagtgata aaagaagaca atgaagagat gtatgatact ttttggaaca agcctcactt
    28141 agtaaaagag tttccaggag aaagcttcag tgagtttgaa aaaagggttg taggaacagt
    28201 attggatatc gctgagagca ataaagggaa agatatttta atagttgctc atgctctagt
    28261 actaaaagtt gttatgagct tttttgagaa tagaccattg gaaaaattgt ttgaagatca
    28321 tttcatgtat tcaacttgtc ttaatgaagt tgagatatta gatggtgatt ataaaatagt
    28381 aaaatataat caaacagatc attatgatat tgaagttggt taagtaagtt ataattataa
    28441 aaagcatttt ggagataata ataagtatat atgttgaata aataattgcc atagagacag
    28501 cgattattca gctattcaac tgatagctta taccaaggag gttactatga aatcgttaag
    28561 aacaattttg acagtagtat ttagtttcgc tgtagttgca gctgttattc tatatacaca
    28621 aatcaagaaa atagctagct caaataatca atcaaaaaaa caagtagata aacaagaaaa
    28681 agatataaag acaacagcaa aaagacctct tgatttttca gcatttgaat cggatcttaa
    28741 taaattagga gaccaaagat acaaagagat tgaaaaatca ttgattgaat cagatattag
    28801 atctatacaa aaaaatattg aatcaggaaa tctaacttat gaagaacttg tattatttta
    28861 tataaaaaga attaaggaaa ttgataataa cagattaaat acagttatac aactaaatcc
    28921 agatgctgta gtagtagcca gagaaatgga tgaaaagaaa aataatggtg aaaaacttag
    28981 tgatctgcat ggtattccag tccttctaaa agataatatt ggaacaggtg ataaacttac
    29041 taatactgct ggtgcaaaag tattagaaga ttcttcatgt gatagagatg cttatattgt
    29101 taagaaacta agagaagcag gagttataat attaggaaag actaatctaa gtgaatgggc
    29161 taattttatg agtattgatt catctaatgg ttattctgca cttggaggac aaacccataa
    29221 tccttatggt aattatgatg ttggagggtc tagttctggt tcaggagcag gagtttctgc
    29281 taattttgct ccattagcta ttggtacaga gacagctgga tcaattatat ctccttctag
    29341 tcaaaacagt gtagtaggaa tcaagcctac agtaggtctt tggagtagag atagaattat
    29401 ccctcttgct attgacttgg atactgcagg acctattgca agaactgttg aagatgctgc
    29461 tatgttacta ggcgaattag ttggtgaaga tgagaatgac attgctactt ctgatgcacc
    29521 tgaaaaagaa gattatacaa catacttaga taaaaatggt ttacaaggta tgagtattgg
    29581 aatagtaact aacaaagaag tgacttctag ttatcgtaat gatgatagtg atattatcaa
    29641 tagaattaag gaagaattaa ttaatctagg tgctgatgta aaaaatgttg aattggacga
    29701 taaagctttc aggatagatg gacatgtaga tatgatggct tatgaatata aaacaggagt
    29761 agaagaatat ctgaatgcca taggtgacaa tgctccagtc aagacaataa aagaaataac
    29821 aggttttaac aaaagagatt tagacagcag agcatattat ggacaatact tcattgagaa
    29881 agcaagggat atcaatatta cagaggaaga aaatacaaaa attttgtccc ataatagatc
    29941 aaatactggt tctgcaatag atgaagcact agaaaatgac aaagttgacg ttttaatctc
    30001 tcttaataat tatctatcag ggatttaccc tatagcaggt tatcctgcaa tcacagtacc
    30061 agcaggatat agagattctg gtgagcctgt aggtttaaca ataaccagta ctaaatttag
    30121 tgaaggtcta ttaataaaag cggcatatgc ttatgaacaa ggtactaagc atagaataca
    30181 gcctaatatg atatagaaat atgatgaatg ttatataata tcaatcagcc tacaactgat
    30241 tgatattgta tttgagttaa tcgggaataa agaaaggatt atatatgaat tatatttata
    30301 tatgtacagt aatacttata ataattagta tcatcttttt cattattgat acaactaata
    30361 taacttcttt tataagtaat gacttaagag ggtttaaatt aattattagt atagcttttg
    30421 cgattttatt accagtgacg attctaagtg gggtatatca tcttaatgat atatcagata
    30481 atcaattata tatatggtta gtcaaatatc catgtgtatt cttgtctttt attggatttc
    30541 aagttatatt atatcgaaat aatgatatta aataatgcct atatatgaga tgttttttta
    30601 tgatatacta tgtaaaataa tattagtata aaggagaaga atagtatgat attatctgga
    30661 cagaaaataa gaagcagatt aggaaaagat atttttatag aaccgtataa tgaagaacaa
    30721 ttgaatccca atagttataa tctaagatta cataatgaat tattagtata tgagaataat
    30781 tcattggata tgaaaaagag taatgacact aaaaagctta ttataccaga agaaggatta
    30841 ttactggagc caggtaaatt atacttggga agaactgttg aatataccaa gaccgacaat
    30901 tatgttccaa tgttagaagg acgatcttct ataggaagat taggattatt catacatgtg
    30961 acagctggtt ttggagatgt aggattcagt ggatattgga ctttggaaat attctgtgtt
    31021 caacctataa aagtttatcc agaagtagaa gtttgtcaga tatattatca cactattgat
    31081 ggtgattatg ataaatatac aagtggaaaa taccaaaata acaagggtat acagccaagt
    31141 ttattatata gggattttga atgattatga ctgacactag aatttaggag aattatatga
    31201 aagtagaatt ttataatttg gatgatttta ataactcttt gaaatttgtt gttatacaag
    31261 ctagatataa agatgaatgg atatttgtaa gacataaaga tagaaacaca tgggagatac
    31321 caggtggaca tatcgaaaaa ggggaaatgc cagatgaagc tgctgctaga gaattatatg
    31381 aagaaacagg ggctatagaa tacgatttat cacctatctg taattattct gtagaaatta
    31441 atgaaagcaa aagttttggt agattatact atgcagaagt aaaaaatatc ggtgagttag
    31501 gtgattatga aatcgctgag ataattacaa aagatgaatt acctgaaaaa ttaacctacg
    31561 ataagattca accaatatta tataaaaaag tattagccaa cattacaatt taattgttaa
    31621 ataaatattt attttaggag atgttattat gattattgtt agagatagaa aaacatataa
    31681 aaaatatata gtattaggaa ctggactggg agcatataaa gctgttcgac caagcttttt
    31741 tgggggcaac ttgttcccac atgaagaaga gggaacggtt aaaactattg ctgtatgtga
    31801 ttcaaagggt gatatatttt ggtttgagtc aaattattta caagtaatag aagttgatgg
    31861 aataaagatt tctgaaatag atttaggaga ataactatgg acttacttgt aataattttg
    31921 ttcggtgtaa ttttaattag ctgtatcctt attagactga agccatttga aaaacacaga
    31981 aaaatatttg gtatagtatt tattttaatt ccccttatta taataattgt aagttatttt
    32041 tatgatgaaa ctgataatat atatgatttt atatttatca atatttattt tattgtgctt
    32101 ttagttatat taacgttgtt agagaaaaaa actagagaaa acacatattc atattttggg
    32161 ttttttatag tattttatgt aataatgttt tattcaatta gaataatgaa tggaagatta
    32221 ttgatatcat taaattatat ggttattgtt ttaacattca ttactaatat taagagtatt
    32281 tataaaagag atgatagaac agtaatgatt tttgcaaata taattggaat cataataata
    32341 ggtatcatga ctatgattta tcctaagtca tatttaacaa gcacaaagca agaacgtata
    32401 ttgaatggtt atctgataaa tgaacaagaa attgatgatg aagatattat tgaaataact
    32461 gtactatcaa atccaagtgt taataatgaa aagagaatat ttgtcaaaat taaggatgaa
    32521 ggtgcattta tctattatta taaaagtgga gaaataacag gagtagaaga aaaagacttt
    32581 agtaagtgag aggggacgac tatatgaagt tagaagaaat aagtagcttt tttaataaaa
    32641 gagtagatgg ttatgaagaa catatgatga cttatgtaga tggagcaaaa gaatattata
    32701 ttgaaacagc aaagataatt ccaaaagtag aaggattgaa attactagat ctaggttgtg
    32761 gaactgggct ggaattggat gaaatattta aagtgaatcc aacaatcatg gttacaggaa
    32821 ttgatatagc aaaaaaaatg acagataaac ttttagataa gtatagaaat agaagtaatc
    32881 aaataaatat aattaatgaa agttatctag aatataatat aggtgaagat atatatgatg
    32941 ttgctctatc tgttcagaca cttcatcatt ttactcacaa agagaaaaca aagatcttta
    33001 gtaagatatt tagaagctta aagcataatg gtatttatgt agaaacagat tatattgctc
    33061 ctaatcaaga atatgaagat tttcattata gcgaaaatgt tagaatgaga aatgaattag
    33121 gtataaaaga agggtattat cattacgata ctccttgtac ttttgaaaat gagaaaaata
    33181 tgttatatga agcaggattt aagtcagtag aaaagatatg gcaaaaagaa aatacggtaa
    33241 ttctagtggc taaaaaataa taatgatgat attaaaataa ttaaaaagtg gagagtgaaa
    33301 agaatggctt ggtgtccaaa atgtaaaagt gaatacgaag ataatgtaaa agtgtgcaaa
    33361 gagtgtaatg ttgagctagt ggaccaattg gaaaatgatg aggttgaata tcagaatttt
    33421 gagtttttaa tcaatgtagg aacagtcaat gaagctaata ttctaatttc tttattagaa
    33481 tcctatgaca tacctacaat tcataagagt aaaggttctg gagaatatct acaagtagct
    33541 acaggaatta attatcaggg ggtggatatc tatgtacctg ctgatgtatt aaccaaagca
    33601 aaagaaatca ttgattattc aaataatgta gatttggatg atgatactca gacagagaat
    33661 ataattgaag ataacaataa ttttgaagac gaagagctag atcaattaga taaaaagaat
    33721 agcagtaaga gacgaactgg gttactaata ttaatactat tattcattgt attaccttta
    33781 cttattgtta ttattagttg gttcatttaa tatgatgcta tgttttgagg ggggagtata
    33841 atggcacata aaatatgtaa gaactgtggt gagtttaata gtgcatccgc catttattgt
    33901 tgtaattgta atagctcatt gagagatgta aaaaagaggg aagatgctat tgatcccata
    33961 aaattcagcg ggaaagctgt aggttacaat tattctgaag aggtaacctt aggtgaatgg
    34021 ataataatct taa
//
