LOCUS       NZ_CP058561            23723 bp    DNA     circular CON 15-DEC-2024
DEFINITION  Vallitalea guaymasensis strain Ra1766G1 chromosome, complete genome.
ACCESSION   NZ_CP058561
VERSION     NZ_CP058561.1
KEYWORDS    RefSeq.
SOURCE      Vallitalea guaymasensis
  ORGANISM  Vallitalea guaymasensis
            Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
            Vallitaleaceae; Vallitalea.
REFERENCE   1  (bases 1 to 5626074)
  AUTHORS   Postec,A.
  TITLE     Vallitalea guaymasensis genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5626074)
  AUTHORS   Postec,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUL-2020) Microbiologie Environnementale et
            Biotechnologie (MEB), Mediterranean Institute of Oceanography (MIO),
            UMR 7294, 163 avenue de Luminy, Marseille 13288, France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. JUNE-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018141425.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 15:20:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,859
            CDSs (total)                      :: 4,781
            Genes (coding)                    :: 4,757
            CDSs (with protein)               :: 4,757
            Genes (RNA)                       :: 78
            rRNAs                             :: 6, 6, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 5 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 24
            CDSs (without protein)            :: 24
            Pseudo Genes (ambiguous residues) :: 0 of 24
            Pseudo Genes (frameshifted)       :: 7 of 24
            Pseudo Genes (incomplete)         :: 16 of 24
            Pseudo Genes (internal stop)      :: 1 of 24
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:55:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1992866
            Orig. end                         :: 2016589
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP058561.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23723
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="5"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..23723
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23723
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13723]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13723
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     gene            485..868
                     /locus_tag="HYG85_RS08965"
                     /old_locus_tag="HYG85_08880"
     CDS             485..868
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015525354.1"
                     /locus_tag="HYG85_RS08965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08880"
                     /product="hypothetical protein"
                     /protein_id="WP_212693171.1"
                     /transl_table=11
                     /translation="MEWWEILLLVLGIIVVVFAILYFVGRKLQGKANDQQSVINQNKMT
                     TSILVIDKKKQKVKDSNLPKMVQDQIPKYIRFRKLPMVKAKIGPKITTLLCDDKVFKEL
                     PVKKMVKVDLAGMYIVGMKGYKK"
     gene            complement(884..2491)
                     /locus_tag="HYG85_RS08970"
                     /old_locus_tag="HYG85_08885"
     CDS             complement(884..2491)
                     /EC_number="6.3.4.2"
                     /GO_function="GO:0003883 - CTP synthase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016285126.1"
                     /locus_tag="HYG85_RS08970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08885"
                     /product="CTP synthase"
                     /protein_id="WP_212693172.1"
                     /transl_table=11
                     /translation="MQTKYIFVTGGVVSGLGKGITAASLGRLLKARGKKVTIQKFDPYI
                     NIDPGTMSPYQHGEVFVTEDGAETDLDLGHYERFINENLSKYSNITTGKIYWSVLNKER
                     KGEYLGATVQVIPHITNAIKERVYRVGKSAQSDIVITEIGGTVGDIESLPFMEAIRQVS
                     AEVGPENVLYIHVTLIPYLAKAGEMKTKPTQHSVKELRSIGILPDILVCRTEHELSEEM
                     KDKMALFCNVKKECVIQNLDADTLYEVPLMLEKEGLAKIVCDKLKLDCAEPDLTEWKEM
                     IDREKSMTNLVKIALVGKYVELHDAYISIVESLKHAGIYHKTKLEVLWVNSEEVTSENV
                     DDYLKDADGILVPGGFGDRGIDGKIFAVRYARENKIPFFGICLGMQCAVIEFARNILGY
                     DGAHSSELDPDTKYPVIDLMPEQKDIDELGGTMRLGAYPCKVQKDSMAYQAYDSELIYE
                     RHRHRYEFNNEYRDTLVKAGLNIVGVSPDDRLVEMIEINDHPWFVGVQFHPEFKSRPNK
                     VHPLFRDFVGASIKAKTN"
     gene            complement(2668..4065)
                     /locus_tag="HYG85_RS08975"
                     /old_locus_tag="HYG85_08890"
     CDS             complement(2668..4065)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00225.1"
                     /locus_tag="HYG85_RS08975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08890"
                     /product="S41 family peptidase"
                     /protein_id="WP_212693173.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 2.5e-41, bitscore:
                     139.1, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIINRIVLTAVVLSMLIVPINVKAVDSVAVERKGEEFKVLFSL
                     IRDNYVGEEVTDEQLFKAAIDGMFDELDPYSTFYTKKEANTLIEAISGEFVGIGVEIVQ
                     DGDWVKVSRPIPKSPAIKAGVRAEDIIIAINGESAENYTPTDAANKMKGKEGTMVSVTF
                     KRGNKEYTVDIKRALVKISAVETEEINDLFPKLDKEVAKKINYIRINSINKNVAEDIEP
                     YLEDAKKEGVKYLILDLRDNLGGYVDSGVALCNMLIPKGPVLHFVNKEGRKITYRSNLR
                     KAPFELVVLTNENTASASEFIAAAVKESGVGVTVGETTYGKGVAQYIYDISDKYSIKLT
                     MEEFLSRDGHKINGIGVAPDYEVIVPNLIVSPERLFLDDEMEEVKNVELILEYLGYAIN
                     EPDNLYDEKTEKAITQFQKNMGLRAYGVSDHPTLKALNTKLIESINKKDIQLEKAMEVI
                     LSKINEN"
     gene            complement(4142..5647)
                     /locus_tag="HYG85_RS08980"
                     /old_locus_tag="HYG85_08895"
     CDS             complement(4142..5647)
                     /GO_component="GO:0030115 - S-layer [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012613.5"
                     /locus_tag="HYG85_RS08980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08895"
                     /product="S-layer homology domain-containing protein"
                     /protein_id="WP_212693174.1"
                     /transl_table=11
                     /translation="MKRISMKILFLIFAFSITSICVYADMGDMGYFGGISEGTNLPKTI
                     EKYVPVKPLKTRVMRYKEMVYISGEPIEFEGTIKVTKNDDVIDTKESGSYNEKYVISAK
                     NLEKNSTLDRTINFTTSFYYVDGDFKKQIVRDSAVSSWTEKIVIDDVTYTLDDTFSIYS
                     LTGVEDITPGVSYYDTSVSYEARFLSSNNETITIKTEGSVYGYDQPWSKVESGKLTMDI
                     IGPKDRMQVTLNPSLEAKKTMYYDKTSPFPISFDGTYNQRLEREASLKYNITTNHPELT
                     RSQMENSIMISTAKQIEKLPIPAGLDFLDSNPANEHMKKLYSMEIMTEIPHKSMELEAI
                     TRGEFIKAICLAMNMDTSKYQVTSKNKNSMKVIFGDVLPDNPLYPYIMTAYNAKLIKGV
                     GDVFKVSQPITRQEALCILIRVIGLEKIGKLENSVTPFKDDNMISPWARKAILAGYKLG
                     IIEEKEGNLEPRKWLSKIDASTIIDNLINYLREDISGYYRLIQ"
     gene            complement(5674..8646)
                     /locus_tag="HYG85_RS08985"
                     /old_locus_tag="HYG85_08900"
     CDS             complement(5674..8646)
                     /GO_component="GO:0030115 - S-layer [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012613.5"
                     /locus_tag="HYG85_RS08985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08900"
                     /product="S-layer homology domain-containing protein"
                     /protein_id="WP_212693175.1"
                     /transl_table=11
                     /translation="MKKIITYLLMFTLMMTALPVYAVTDPSVLKEPVQNVYLARSGAEG
                     IIENLKFSDVSPSSWSIEPITRFGALQIIKGYNENNAKKYRPSAPISNEESLAVLLRIL
                     GMEEAAQKAGNQLLQENPELPDHVLTLWSKGYLQLAKNMGLITEDDLDNALVEEQWELD
                     PSESFIKRGPVTREQLAVWIVKAINSKQPDLISPLYKQKDVFNYSDWEKIDREFIPYVE
                     AVIQKKIMVGSNNKFNPKGIVTREQMAQTLKNLDDIAYNTMNITKENGTVAYIEDSNSM
                     GASDSIATRRILITDENGKVNEVNYEYKRKSNDQILTKDVPVLINGVVGGLLNLREGEY
                     IEYLVNNDTKEMLYASSKGINEPYELEGVLQPLNEIDNGRITITSDRGINYTFQMKSAV
                     YNNVDGTIKINDINVKIPNAPISSKVKLYIDNNIVTKIELAGDKVIFDTLSGIVKENNP
                     TFNYITIMTWDGKEVTKYYQKKSVQVEKQQYYDTEDEIGYIDEMFPDFRFDPRDTTIDD
                     VEAGDLVDIKISPDGKNVLSISAKTNYIVKYGSINQIVNNGANGLRLWVKFDDLSSTIY
                     DIDSNIPVKRAGQNISQYQLQEGQVVKLLINQAVFEPGTITESVKEIQVDEYGNTVANI
                     YKGKLGSLNNSQRTLTLLNSYELTKAGWRDYTKSKILDISSKNIEYYLDSKQISLDYAL
                     NYLKSPDIDVYVAMEKYYDDEKVLKVTFGTGRENILASDNVTYSNGNNKFKVLQSPNYI
                     NTHDGTIVVKNGKLLEDNNIVSPDYAQVILNGNGKAVIVNITKEPSNEATSIFRGRIKS
                     INENEDMQVQSFALLKGMKWIYSPIPRMFTTDYETVIMDANGIIPQTDFLDYSEKTKVD
                     KVYTIISDGTKAKYIIENPYCLDGVKGEIYETESGAISIKDTIVYNKTNNSWKDLSYSN
                     SYAKINLKTNTIIIKNNEVISPDMLEKGDIIRVITDEYLITKLATKGARDVDGYIILVE
                     K"
     gene            complement(9014..9406)
                     /locus_tag="HYG85_RS08990"
                     /old_locus_tag="HYG85_08905"
     CDS             complement(9014..9406)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022281.5"
                     /locus_tag="HYG85_RS08990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08905"
                     /product="DUF2752 domain-containing protein"
                     /protein_id="WP_212693176.1"
                     /transl_table=11
                     /translation="MVIFNILIIIALALIIIVSAIAHIKDDKVYLTNNIIIGKCAVKEM
                     TGHDCPSCGLTRSFVSISNGRFIRSFDYNYAGLPLYLLVICQIINSSIFLFRKKYNSYI
                     SKFNTIFSVGICFTIIASWLLHILLK"
     gene            complement(9417..9716)
                     /locus_tag="HYG85_RS08995"
                     /old_locus_tag="HYG85_08910"
     CDS             complement(9417..9716)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025198.5"
                     /locus_tag="HYG85_RS08995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08910"
                     /product="DUF4190 domain-containing protein"
                     /protein_id="WP_212693177.1"
                     /transl_table=11
                     /translation="MSDFNNPNQEVKFKGLSIASMVCGIVGIVFFCFYYLSIILAILAI
                     IFGAVFLNANKVNEDKSGRSMAIAGLVLGIVTIGLVVLVVAGLFSAVSQLDNFV"
     gene            10001..10615
                     /locus_tag="HYG85_RS24760"
                     /old_locus_tag="HYG85_08915"
     CDS             10001..10615
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.5"
                     /locus_tag="HYG85_RS24760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08915"
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="WP_212693178.1"
                     /sec_met_domain="AgrB (E-value: 4.8e-31, bitscore: 105.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIDRPINVLTYHLYKNTLIPHKNIRVMRYGIYVLYSEFVKLAIL
                     TIFFSLIGTLNEFLFALVILLLIRPYSGGIHFNSFMGCFLFTIGFFILNVAILPSLNYI
                     NNPSLYIVLFPINLLIIFLCSPMPSKHRPIKNKKTKNKYKYLATFFTAAIYTALLLTNI
                     DPTFKAIGLWTINLQAIQLLIGGGVTREKIQKTKLFSILNS"
     gene            10569..10706
                     /locus_tag="HYG85_RS09005"
                     /old_locus_tag="HYG85_08920"
     CDS             10569..10706
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HYG85_RS09005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HYG85_08920"
                     /product="hypothetical protein"
                     /protein_id="WP_212693832.1"
                     /transl_table=11
                     /translation="MKKFRKQNYFLYSIVSFFVFLSWFPVNRASWLLFGEVPCPKCLQK
                     "
     gene            complement(10709..11965)
                     /locus_tag="HYG85_RS09010"
                     /old_locus_tag="HYG85_08925"
     CDS             complement(10709..11965)
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025854.5"
                     /locus_tag="HYG85_RS09010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08925"
                     /product="sensor histidine kinase"
                     /protein_id="WP_212693179.1"
                     /transl_table=11
                     /translation="MEFVYFIIMNILEITSLILVLSKIDKRLFLKGPMYKVILIVLHII
                     IVTLFIYFNIPLKEVMLGIAILLVFKLITDISVKLLIFEYTIATIYLLSIQLMIVFLFQ
                     LLGIIKQNDFIAISCNLILLVISIFTYRYIPLNEIVTLYNRFKKIIQWLIILIAIPLGI
                     YFVSWKIDFNSVNYISLIIVGIITWTLIVAIVFKQLLQIKQKQKANEIYMEYNPILENL
                     LDDVRAKQHDIKNQLNAIYGIAEKSQDNELLDYLNTVIDGYQLHSDDILLNTGNNIISA
                     ILYSKKIKARQNNIELNCNCYTPFPKYPIEDYEFVDILGNLIDNAIEAATNYQSAIKKE
                     VHVNLFEENNSTVIEVKNTSLPVKFETLDKVFEKGYSTKGNNRGFGLYNVNKIVKSYKG
                     NIQISYEEEQICFKILFGG"
     gene            complement(11967..12713)
                     /locus_tag="HYG85_RS09015"
                     /old_locus_tag="HYG85_08930"
     CDS             complement(11967..12713)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="HYG85_RS09015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08930"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_212693180.1"
                     /transl_table=11
                     /translation="MNNILIVEDNDTSRNNLEYVLKTNFSDVRIYKAGTGKTALKLLKE
                     IRMDLFFLDIQLPDISGLKIAEIIRSIEQYELSYIIFITTHLMYLPKAVQEYHCYDFIE
                     KPFTKSKIIDVTNKLLKGINKVNKENKVDKKYITIKLKNVIHKVSVNDIFYAESCRRKL
                     YLHTTLGKIVIPSMTFKQMIEMLQETGVDYFVRTHRSYVVNINHIRSIEKHNKKAWDIN
                     FYDYEEVALIGDKYSVDVINRIEGGI"
     gene            complement(12978..13130)
                     /locus_tag="HYG85_RS09020"
                     /old_locus_tag="HYG85_08935"
     CDS             complement(12978..13130)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04223.1"
                     /locus_tag="HYG85_RS09020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08935"
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="WP_113672633.1"
                     /sec_met_domain="TIGR04223 (E-value: 2.1e-12, bitscore:
                     45.0, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLATINEKVSTKLLGLVGLIGIAVASLSVQTACIWFFNQPKVPEK
                     LRKND"
     gene            complement(13124..13723)
                     /locus_tag="HYG85_RS09025"
                     /old_locus_tag="HYG85_08940"
     CDS             complement(13124..13723)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.5"
                     /locus_tag="HYG85_RS09025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08940"
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="WP_212693181.1"
                     /sec_met_domain="AgrB (E-value: 8.1e-40, bitscore: 134.3,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIYEFSNKISSKLIGKKIIKEDDKEVYTYGFEIIISSLLILIGMV
                     ILGIIFRCLLKVIVFILFFCSLRVQAGGYHAKSHWKCFIYFLLSCFLAILISHLLLDFD
                     KNLIIIILVLIESCIIIITYAPVDTVNKPLGSSEKVAYKKKSMITVIVQSIIIIAMSIF
                     LNSLESYYMVAAIAVFMESLTVLPIINKKESEVKIC"
     gene            complement(13822..15141)
                     /locus_tag="HYG85_RS09030"
                     /old_locus_tag="HYG85_08945"
     CDS             complement(13822..15141)
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025854.5"
                     /locus_tag="HYG85_RS09030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08945"
                     /product="sensor histidine kinase"
                     /protein_id="WP_212693182.1"
                     /transl_table=11
                     /translation="MIWYLIELFVDIVEALIIIKFCSSVYKKRYNSIIAYYVGGFSITA
                     IIFIFNYFSYDLDCTFRGSFLGMIIIMFVVVLALYDEKIMKLLLGYIGLLILIVAIEGI
                     ILSLLSFIFGESPAVFAKSNILRVLGMVVSKLITFLVIVLFISDGERFGLRFLKKSLLI
                     EIITLFIINLGIMISIVPMYRNLMYENNEDSIVAGFVILGLGIVNIVSLLIYDKLLAQS
                     KKDLELQLKIQQYEMQSKYFDEINNATLKLKSLRHDMSNHLGNIKGLLRYKEYTKLEEY
                     LNKLLSQIDEVDKIIITKYPAISALLNRKYARAGNNNINCVMNIGSVDNLTIDTVDICI
                     ILGNLIDNAIEATVKVDENNRYIKLDINNVNNYLVIDCVNSTIGSENISLDTTKEDKEI
                     HGIGLMNINQIVEKYYGNMEIMCIKDYFSVNIMLYNGELN"
     gene            complement(15138..15869)
                     /locus_tag="HYG85_RS09035"
                     /old_locus_tag="HYG85_08950"
     CDS             complement(15138..15869)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012301.5"
                     /locus_tag="HYG85_RS09035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08950"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_212693183.1"
                     /transl_table=11
                     /translation="MKFNIAICDDEILQVNLVEKLIMEAIETKNIKVNILKFLCGEDLI
                     TYCNSNKLHIIFLDMEMKGLDGIESARKIREINDNVIIIFVTGYKEYVFDVFEVNTFRY
                     ILKPVKIEQFQKALFDAIKLIDELKEPQKEEEFLVINKNKEKIIIAYNSINYFEKYKNK
                     VMVMADNQNIEFYGTFNELNMLLNEDKFIRVHQGYIANIDKIELITSKEVLLKNGKRIP
                     VSRRNAKEVKETFLSRKRVKL"
     misc_feature    16149..16165
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 25.23"
                     /tool="antismash"
     gene            complement(16245..17135)
                     /gene="galU"
                     /locus_tag="HYG85_RS09040"
                     /old_locus_tag="HYG85_08955"
     CDS             complement(16245..17135)
                     /EC_number="2.7.7.9"
                     /GO_function="GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006011 - UDP-alpha-D-glucose metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="galU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016288198.1"
                     /locus_tag="HYG85_RS09040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08955"
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="WP_212693184.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.2e-08, bitscore:
                     33.6, seeds: 297, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.9e-08,
                     bitscore: 30.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIRKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIVEEAV
                     SSGVQDIIIVTGRNKRSIEDHFDKSIELELELEKKGKDDLLEIARSVSEIANIHYIRQK
                     EPRGLGHAILMAKHFIGNEPFAVLLGDDVIVSKKPCLQQMIDVYSEYRTSILGVQKVPI
                     DDVSKYGIIDAKHIEDRIYKIKDLVEKPLSEDAPSNIAILGRYIISPSIFKYLETQEAG
                     AGGEIQLTDSLKRLARDEAIYAYDFIGKRYDVGNIMGFLQATVESALRRDELRDDFLGY
                     LKHTIDNVDNVIKVD"
     gene            complement(17170..17652)
                     /locus_tag="HYG85_RS09045"
                     /old_locus_tag="HYG85_08960"
     CDS             complement(17170..17652)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020711.5"
                     /locus_tag="HYG85_RS09045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08960"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_212693185.1"
                     /transl_table=11
                     /translation="MTKDVLVRVKGVQTDMFESDEIELVTTGSYVEKNNKVYITYIDST
                     IDGDKETKTTIKHEKDQISILRFGGVNSHMVFEKDKTHITHYQTPYGIFEINTHTKKIN
                     VEREEDFMEINVSYDLSINHMSMGVNTFTITVKNAKSDRVVLMDDKNVEIENEELS"
     gene            complement(17676..18731)
                     /locus_tag="HYG85_RS09050"
                     /old_locus_tag="HYG85_08965"
     CDS             complement(17676..18731)
                     /EC_number="6.3.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008719830.1"
                     /locus_tag="HYG85_RS09050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08965"
                     /product="D-alanine--D-alanine ligase family protein"
                     /protein_id="WP_212693186.1"
                     /sec_met_domain="Dala_Dala_lig_N (E-value: 3.9e-34,
                     bitscore: 115.5, seeds: 508, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 8e-68, bitscore:
                     226.1, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.5e-08, bitscore:
                     32.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKRNIVVLFGGQSSEHEISCISAVTIMKNINKDKYNIYPVGITK
                     EGNWRIYHGKIEDLTVDSWVGNSDNAIISPDATDKSLIIFKEDGIVKVDVDIVFPALHG
                     LYGEDGSVQGLLELAGIPYVGCGILASSVSMDKLFTKVIVDRLGIRQAKYVPVYKKEMD
                     DIKEVVAKIERQLEYPVFVKPSNAGSSKGITKAHNRGELFDGLELAIKHDSKLLIEETI
                     VGREVECAVLGNYHPRTSNVGEIISAAEFYDYDSKYNDIGSKTIINPDVPKITLKKIRD
                     CAEQIFRAVDGRGLARADFFIEEESGEVVFNEINTLPGFTSISMYPMLWEDKGMSNEEL
                     VDRLIEFAFNK"
     misc_feature    complement(19022..19037)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 23.98"
                     /tool="antismash"
     gene            complement(19084..19815)
                     /gene="spoIIR"
                     /locus_tag="HYG85_RS09055"
                     /old_locus_tag="HYG85_08970"
     CDS             complement(19084..19815)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIR"
                     /inference="COORDINATES: protein motif:HMM:TIGR02837.1"
                     /locus_tag="HYG85_RS09055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08970"
                     /product="stage II sporulation protein R"
                     /protein_id="WP_212693187.1"
                     /transl_table=11
                     /translation="MKVNLMKVFEKKRILRTYILSLLIVILMLAAIVYDYGKNGTSAAV
                     IEGISDSLIRFHVIANSDSEEDQKLKLKVRDEILDRMNGILEESENIEETRQLITDNRD
                     EIKRIAERVIEENNYDYDINVKLKMEQFPLKTYGDIILPPGEYEALLVEIGEAKGKNWW
                     CVMFPPLCFVDVTHGVVPEETKETLKRVLTDEEYDSIVMAEPEEDMPIKIRFKFLEWFN
                     FSRDKDRDRQDNDSKVFVNRD"
     gene            complement(19949..21064)
                     /locus_tag="HYG85_RS09060"
                     /old_locus_tag="HYG85_08975"
     CDS             complement(19949..21064)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009847 - spore germination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02887.1"
                     /locus_tag="HYG85_RS09060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08975"
                     /product="Ger(x)C family spore germination protein"
                     /protein_id="WP_212693188.1"
                     /transl_table=11
                     /translation="MKIKVMAILVICSILLVGCWDKVELNDRAYVISLALDDIGDLLEV
                     TYTIPNLPVITAQSGGEATKFIKVTKAETLTQANRAFGKKSNLRINFDHTKVIIFGADF
                     LNDPHNLRKVLDHFDRNPEYSKALLLLGTKETGKKLLESVPNGEETTGIYLSQVFINNS
                     LETISAKTIELGDFISQMYSTEGNGVMPNVIFRDNEVIVDGLAILRDYQLRGWMEDKYM
                     TPYSWILGKGKETVALVDMEGVLVPYEISDLTSKMDFELKDGLLKIKISISSEGDVSEY
                     ILEDKDKLFSTSYIAEIENEVANSMEEDIYELMNIIQEEYGIDIINAYNNLKTSNRKVW
                     KTTKSDWQNFFNAAAIEVECKVNIRRVGLSK"
     misc_feature    complement(21039..21059)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.6"
                     /tool="antismash"
     gene            complement(21096..22196)
                     /locus_tag="HYG85_RS09065"
                     /old_locus_tag="HYG85_08980"
     CDS             complement(21096..22196)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009847 - spore germination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00912.1"
                     /locus_tag="HYG85_RS09065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HYG85_08980"
                     /product="endospore germination permease"
                     /protein_id="WP_212693189.1"
                     /transl_table=11
                     /translation="MFSQNNKISMRQVEILIILNMFSNTSLILPRIASEIADGDGHFIV
                     LGGAIISLVYVFIITSLVKMFPDKNIVEYTELIFNKPIAIIIGVVFCLKLIILAGLEIR
                     VFGELVKQALLRNTPIEIIVIAMLLVVVYLTRKGYEARARMAELLIFIILIPLVVIFFF
                     AVPDIKLYNISPIFSISGEKFIYGSLIMSFAYSGIELLLLSSPYVINPDKLPKVTLRSV
                     AFVGVLNALICILTIGSFGPIETSRQIWPVMTIMQTIHLPGALIQRQDALMVSFWIMTV
                     FLLINAYLFFSGLLIKKIANLKEQNFLILPLIPIIYLISLIPDNIVETYKWIEIMTRYV
                     SLLFLLPIPLILLVVAKMRGLGKTSK"
     misc_feature    22724..22735
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.06"
                     /tool="antismash"
ORIGIN
        1 ctaatttcag ggaaggtctg aaaataatcc tagctggtat agaaatgttg aaatcaggtc
       61 tatcaatgct aattttccct gaaggcacta gaaacaaaga atctgaagag cctttacctt
      121 tcaaacaagg tagcttgaag ttagcagaaa aagctaatgt acctattata ccatttggca
      181 taaaaggaac agataatatc tttgaaaaca ataatggtgt tgttgtaaaa ccaagcaaag
      241 taacgcttaa ttttggtaaa cctattcttt taagtgaatt gccacaagag gatatgaaaa
      301 aaagtgctgt ttatgttcgt tctgaaatcc tccaattact ttctaagtag gatagtaaaa
      361 ctgaaaaact ataaaatgca gaggaaattt gatgttttag caaatttcct ctttgatttt
      421 tatgtaatta atgatagaat atatagaacg cactaataag tatcttttca aaggaggtgc
      481 acctatggag tggtgggaaa ttctattgct tgtattagga attattgttg ttgtatttgc
      541 tatcctttat tttgtaggaa gaaagttaca aggtaaagct aatgaccagc aatcagtaat
      601 taatcaaaac aaaatgacaa catctatact tgttatagat aagaagaaac agaaagtaaa
      661 agattctaat ttgccaaaaa tggtacaaga ccaaattcca aaatacattc gttttagaaa
      721 attacctatg gtaaaagcaa aaatcggtcc taaaattact actttattgt gtgatgacaa
      781 ggtattcaaa gaattgcctg ttaagaaaat ggtaaaagta gatttagctg gtatgtatat
      841 agtcggaatg aaaggctata aaaaataaga aaaagccaag acattaattt gtcttggctt
      901 ttatacttgc tcctacaaag tctctgaata atggatgcac tttgttaggt cttgatttga
      961 attctgggtg aaattgaaca ccaacgaacc atggatggtc atttatctct atcatctcaa
     1021 caagtctatc atctggagat actcctacaa tgttaagtcc tgctttcaca agtgtatctc
     1081 tatattcatt gttgaactca tatctatgtc tatgtctttc gtagatcaat tcagaatcat
     1141 aagcttggta tgccattgaa tccttttgaa ccttacatgg ataagctcca agtctcatag
     1201 taccacctaa ttcatcaata tccttctgtt ctggcatcaa atcaataact ggatattttg
     1261 tatcagggtc aagttcagaa ctatgagcac catcatatcc taagatattt cttgcaaatt
     1321 caataactgc acactgcatt cctagacata taccaaagaa tgggatcttg ttttctctag
     1381 catatctaac tgcaaagatt ttaccgtcta tacctctatc tccgaatcca ccaggaacta
     1441 atattccatc agcgtctttt aagtaatcat ctacattttc actagtaact tcctcagaat
     1501 ttacccatag aacttctaac ttggttttat ggtatattcc agcgtgtttc aaggattcta
     1561 caatagaaat atacgcatca tgcaattcaa catatttacc aactaatgca atcttaacaa
     1621 gattagtcat ggatttttct ctatctatca tttctttcca ttcagttaaa tcaggctcag
     1681 cacaatcaag cttcaattta tcacatacaa tcttagctag tccttctttt tctaacatca
     1741 atggaacttc atataaagta tctgcatcaa ggttttgaat aacacattct tttttaacgt
     1801 tacagaaaag agccatcttg tctttcattt cttctgataa ttcatgctct gttctacata
     1861 ctagtatatc tggtaaaata ccaattgaac gtaattcttt tacagagtgc tgtgtaggct
     1921 tagtcttcat ttcaccagct ttggcaagat aaggaataag ggttacatgt atatataata
     1981 cattttctgg tcctacttca gcggatactt gtcttatggc ttccataaat ggcagacttt
     2041 caatatctcc aactgttcca ccaatctctg ttataacaat gtctgattgt gcgctttttc
     2101 ctactctgta aactctttct tttatagcat tagttatgtg tggaataact tgaactgttg
     2161 cgcctagata ttcccctttt ctttctttgt taagtacaga ccagtagatt tttccagtag
     2221 taatattact atacttgctg agattctcat ttataaatct ttcgtaatgt ccaaggtcta
     2281 agtctgtctc tgctccgtct tcggtaacaa atacctctcc atgttgatac ggactcattg
     2341 tgccagggtc aatattaatg taagggtcga atttttgtat tgtaactttc ttacctctag
     2401 cctttaaaag tcttcctaat gaagcagctg ttatgccctt tcctagtccg gaaacaacac
     2461 ctcccgtaac aaaaatgtat ttcgtttgca tcctcatttc acctcatagt ctttttttat
     2521 ttaaatgatt actctataaa aagtagtcta aacaattttg ttcttactac tttttataat
     2581 gaaccttata tacttttggg ttatcaattt ctattttata caacctcttt attttattat
     2641 tagttagtga aatagtcaat aacaaattta attttcgttt attttactta aaattacttc
     2701 catagccttc tctaattgta tatctttttt gttaatactt tcaattaatt ttgtattgag
     2761 tgcttttaga gttggatggt ctgaaactcc atatgctctt aatcccatat ttttctgaaa
     2821 ctgtgttata gccttctcag tcttttcatc gtacagatta tctggttcat taatagcata
     2881 acccaaatat tctaaaatta attcaacatt tttgacttct tccatttcgt catccaaaaa
     2941 tagtctttct ggactgacaa ttagattagg tactatcact tcataatctg gagcaacacc
     3001 tataccattt attttgtgcc catctcttga taaaaattcc tccatagtta attttataga
     3061 atatttatct gatatatcat aaatatactg tgctacacct tttccatagg ttgtttctcc
     3121 aactgtaaca cctacacctg attcttttac agctgctgca atgaattcag aagctgaagc
     3181 tgtattctca ttagtaagta ctaccagttc aaaaggagct tttcttagat tacttctata
     3241 agttattttt cttccctctt tattgacaaa atgaagaact ggtcccttag gtattaacat
     3301 attacataga gccactcctg aatcaacata tcctcctagg ttatctctaa gatcaagaat
     3361 caaatatttg actccttctt tcttagcatc ctctaggtag ggttctatat cttcagctac
     3421 atttttattg atagaattta ttcttatata atttatcttc ttggctactt ctttatccaa
     3481 cttagggaat aaatcattaa tttcttcagt ctcaacagct gatattttta ctaaggctct
     3541 ttttatatca actgtatatt ccttgttccc tcttttgaag gtaacagaga ccatagttcc
     3601 ctctttacct ttcatcttat tagccgcatc tgtaggtgta taattctctg cactttctcc
     3661 attgattgca attataatat cttccgctct aactcccgct tttatagctg gtgattttgg
     3721 tataggacgg gataccttta cccaatctcc atcttgtact atctcaacac caatacctac
     3781 aaattcacct gatattgcct caatcaaggt gtttgcttct ttcttggtat agaatgttga
     3841 gtaagggtct aattcatcaa acataccatc tatagctgcc ttgaataact gttcatctgt
     3901 tacttcctca cctacataat tatcccttat taggctaaac aatactttga attcttcccc
     3961 tttacgctca acagctactg aatctactgc tttcacgttg ataggtacta tcaacatgga
     4021 taatacaact gctgtaagaa caatcctgtt aattattttt ttcatctttt atcccttctt
     4081 acttgtttga tttatcattc tgatcaatgt aatcattaat ccattttatg taaactataa
     4141 tttactgaat caatctataa taacctgaga tatcttctct taggtaatta atgagattat
     4201 caattattgt acttgcatct atcttggata accacttcct aggttccaga ttaccctctt
     4261 tttcttctat gatccctaac ttgtaaccag ctaatattgc ttttcttgcc caaggtgata
     4321 tcatgttatc atccttgaat ggagtcacag aattctctaa tttacctatc ttctcaagac
     4381 caataacacg aatcagtata cataatgctt cttgtcgtgt aataggttgt gatactttga
     4441 aaacatctcc tacacctttt ataagtttag cattataagc tgtcataatg tatggatata
     4501 gtgggttatc tggtaacaca tcaccaaata tcactttcat gctattcttg tttttactgg
     4561 ttacttgata tttacttgta tccatattca tagcaagaca aatagctttt atgaattcac
     4621 ctcttgttat tgcttctaat tccatagatt tatgaggaat ctcagtcatt atttccatac
     4681 tgtacaattt cttcatatgt tcatttgctg ggttgctatc caagaaatca agtcctgctg
     4741 gaataggaag tttttctatt tgttttgctg tactaatcat tatactgttt tccatttgac
     4801 ttctagtcaa ttctgggtga ttagttgtta tattgtattt taatgatgct tctctttcaa
     4861 gtctttgatt ataagttcca tcaaagctga ttggaaaagg agaagttttg tcatagtaca
     4921 tagttttctt agcttctaat gatggattaa gtgttacttg cattctatcc ttcggtccta
     4981 ttatatccat agtaagtttt cctgactcaa cttttgacca aggttggtca tatccgtaaa
     5041 ctgaaccttc tgtttttata gtgattgtct cattattact tgataggaat ctagcttcat
     5101 aagatacaga tgtatcataa tagctgaccc ctggtgtaat atcttctaca ccagttaatg
     5161 aatatatgga aaatgtatca tctaaagtat aagttacatc atcaataaca attttttctg
     5221 tccagctact cactgctgaa tctctgacaa tctgtttttt aaaatctcca tcaacataat
     5281 aaaatgaagt tgtaaaattg atagtcctat caagtgtact gtttttctcc aagttcttag
     5341 cgcttattac atatttttcg ttataactgc ctgattcttt tgtatcaatt acatcatcat
     5401 tcttagtaac ttttatagta ccttcaaatt caattggttc accagaaata tagaccattt
     5461 ccttataacg cataactctt gtttttagag gttttacagg aacatacttc tcaatggtct
     5521 taggcaggtt agttccttct gatatacccc caaaataacc catatcaccc atatctgcat
     5581 agacacatat gcttgtgata ctaaaagcga atatcaaaaa taatattttc atgcttattc
     5641 ttttcataga ttgtccacct ctttctagtt attttatttc tctacaagaa taatatatcc
     5701 atcaacatct ctagctcctt ttgtagcaag tttagtaata agatattcat cagtgattac
     5761 cctgattata tcaccctttt ctaacatatc tggtgatatg acttcattat tcttaattat
     5821 aatcgtatta gtcttaagat taatcttagc atagctatta ctgtaactta gatctttcca
     5881 gctattattg gttttgttat atactattgt atcttttata cttattgcac cactctcagt
     5941 ttcgtagatc tcacccttta ctccgtctag acagtatgga ttctcaataa tatattttgc
     6001 ttttgttcca tctgagataa tagtataaac tttatctacc tttgttttct cagagtaatc
     6061 caagaaatct gtttgtggaa ttattccgtt agcatccata atgaccgttt cataatctgt
     6121 agtgaacata cgtgggatag gtgaatatat ccacttcatt ccttttagta atgcaaatga
     6181 ttgaacctgc atgtcttcat tttcatttat actcttaata cgtcccctga atattgatgt
     6241 agcttcatta cttggttctt tagttatgtt aactattaca gccttcccat taccattcaa
     6301 gataacttgt gcataatcag gtgatactat gttattatct tctagaagtt ttccattctt
     6361 aactacgata gtaccatcat gagtattaat gtaattagga ctttgcaata ccttgaattt
     6421 attatttcca ttggaatatg taacattgtc actagctaat atattctctc ttcctgttcc
     6481 aaaagttact tttaacactt tttcatcatc ataatatttc tccatagcta cataaacatc
     6541 gatatctggt gattttagat agtttaatgc ataatcaaga gatatctgct tggaatctag
     6601 gtaatactct atattcttgg atgaaatatc taatatcttg gatttggtat aatctctcca
     6661 tcctgctttg gttaattcat aactatttag tagagtcagc gttctctgtg aattattaag
     6721 actgccaagt tttcctttgt agatgttagc tacagtatta ccatattcat caacttgaat
     6781 ttctttcact gattcagtaa ttgttcctgg ttcaaaaaca gcttggttaa taagcaactt
     6841 gactacttgt ccttcctgca gctgatattg agatatattc tgccctgccc tttttacagg
     6901 tatgttggag tctatatcat atatagttga actaagatca tcaaacttaa cccataaacg
     6961 taatccgttg gctccattat tgacaatctg attaatactt ccatacttaa caatataatt
     7021 ggtcttagca cttattgata atacgttttt tccatctggt gatattttaa tatctactaa
     7081 atcacctgct tccacatcat ctattgttgt atctcttgga tcaaatctaa agtcaggaaa
     7141 catctcatct atataaccga tctcatcttc tgtatcataa tattgttgct tctcaacttg
     7201 aacacttttc ttttgataat attttgttac ttcttttccg tcccaagtca ttatagttat
     7261 ataattaaaa gttgggttgt tttcttttac aataccgctt aatgtatcaa agatgacctt
     7321 atcacctgca agttctattt tagtgactat attgttgtct atatacaatt tcactttgct
     7381 gcttataggt gcattaggta ttttaacatt gatatcattg atttttattg tgccatcaac
     7441 attattatat actgctgact tcatctgaaa agtataattg attcctctat cacttgttat
     7501 agtaattcta ccattatcta tttcattaag aggctgtaat actccttcaa gttcataggg
     7561 ctcatttatg cccttactag aagcatacaa catttctttt gtatcattgt tcactagata
     7621 ttcaatatat tcgccttctc ttagattaag aagacctcca acaactccat ttatcaatac
     7681 tggtacatct ttagttaata tttggtcgtt tgattttctt ttatattcat aattgacttc
     7741 attgactttt ccattttcat ctgttatcaa tattcttctt gtagcgatac tatctgaagc
     7801 acccattgaa ttactgtctt ctatatatgc tactgtacca ttttccttag tgatattcat
     7861 agtattgtaa gcaatatcat caagattctt tagggtctga gccatctgtt ctctagtaac
     7921 tattcctttt gggttaaatt tattattact tcctaccatt atctttttct ggattactgc
     7981 ttctacataa gggatgaatt ctctatcaat cttttcccaa tcactgtaat tgaaaacatc
     8041 tttttgcttg tataatggac tgattaggtc aggctgttta ctattgatag cttttactat
     8101 ccatacagct aattgctctc ttgttaccgg tcctctttta ataaaactct ctgatgggtc
     8161 taattcccat tgttcttcta caagagcatt atccaaatca tcttctgtta ttaaccccat
     8221 gtttttcgct aattgaagat atccttttga ccatagtgtc agaacgtgat caggcaattc
     8281 tggattctct tgtaataatt gattccctgc tttttgtgct gcttcttcca tacctaatat
     8341 tctaagtaat actgccagag actcttcatt acttattggt gcagatggtc tgtatttctt
     8401 tgcattattt tcgttgtatc cttttattat ctgtaatgca ccaaaccttg taataggctc
     8461 tattgaccag ctactaggac ttacatccga gaacttgaga ttctctatga ttccttcagc
     8521 gcccgacctt gctagataca cattttgcac tggttccttt aatacgctag ggtctgttac
     8581 agcatatact ggcaatgcag tcatcattag tgtgaacatt aataagtaag ttataatttt
     8641 tttcatttac cccatcctcc gttataaaat atatatcagt attttttccc gaccaattaa
     8701 ttgtaatcaa taatcagaca caggaaatga aatacatttt gtacaaatct atccaataca
     8761 ttatatcata atatttcggc aaaatgggac taaaattgcg ctgttatatg attgtaacaa
     8821 ttaatgagcc aatccaccta agactatttt gctagagaaa ataagagttt caattaaata
     8881 tagtcatagt tactcaaaaa tttatgaaaa gtcactacat cacatcttcc ttagaaaact
     8941 ttcatataaa ataaaaaaat ggaaaataga tttactagtt aaatactatt ttccaaattc
     9001 aaaggagaga tacttatttt aataaaatat gcaataacca gcttgcaata atagtaaaac
     9061 aaatacctac actaaatatt gtattaaatt tacttatgta cgaattgtac ttttttctaa
     9121 ataaaaatat actactattg ataatttgac aaattacaag taagtaaaga ggcagtccag
     9181 cataattata atcaaatgac cttatgaatc taccattact aatggataca aagcttcttg
     9241 ttaatccaca tgaaggacaa tcatgccctg tcatttcttt tactgcacat ttgccaatta
     9301 taatattatt tgttaaataa accttgtcat ctttaatatg agctattgct gacactataa
     9361 taattaaagc aagagctatt attattaaga tattaaagat aaccatataa tttatcttat
     9421 acaaaattat ctaattgaga aactgctgaa aaaagtccag ctacaactaa tactactaaa
     9481 ccaatagtaa caattcctag tacaagacct gctattgcca tacttcttcc tgatttatcc
     9541 tcgtttactt tgttagcatt aagaaatact gctccaaaga ttatagctaa tatggctaat
     9601 ataatagata agtaataaaa acaaaaaaat actattccga ctataccaca taccatagat
     9661 gctatagaca gacctttgaa ctttacttct tggtttggat tattaaagtc tgacatactt
     9721 atttcctcct tcaatcttta taggggaatt ataccatatt attgtatatt tttccataaa
     9781 gttataatta atccaaatgt ttctaattaa ttaattatta gaaagcttct atgatacaac
     9841 aataacctaa tttcatatat gtacaaacag gggttttaat gtaacaaaac ttctttgtct
     9901 gcattttaaa acagatagaa tcctaattga aacataatcc atagttattg cttgtattct
     9961 atgatatctt atagccatat caatacaaag ggtgaatgta atgcttattg ataggccaat
    10021 taatgtactg acgtatcatc tatataaaaa tactctaata ccgcataaaa atattagagt
    10081 aatgagatat ggtatatatg tcttgtatag cgaatttgta aagcttgcca tattaacaat
    10141 attctttagc ttgattggaa cgctaaatga atttttattt gctttagtta ttctcctttt
    10201 aattaggccc tatagtggag gaattcactt caacagtttt atgggatgtt ttttatttac
    10261 cattgggttt ttcatcctaa atgttgctat tttaccaagt ttgaactata taaacaatcc
    10321 ctcactttat atagttttat ttcccataaa cttgttgata atatttttat gttcacccat
    10381 gccctcaaaa catagaccga ttaaaaataa aaaaactaaa aataaatata aatatttagc
    10441 tacgtttttt accgcagcaa tttatacagc cttattactt acaaacattg atcctacttt
    10501 caaggcaata gggttatgga ctattaatct tcaagctatc caattattaa taggaggagg
    10561 tgtaacacgt gaaaaaattc agaaaacaaa attattttct atactcaata gttagtttct
    10621 ttgtattctt atcttggttt cctgttaaca gagctagttg gttattgttc ggtgaagttc
    10681 cttgtccaaa atgtttacaa aaatagtttt atcccccaaa taatatttta aaacatattt
    10741 gttcttcttc gtaagatatt tgaatatttc ctttatacga tttaactatt ttatttacat
    10801 tatataatcc aaagcctcta ttattgcctt ttgttgaata tcctttttca aatactttat
    10861 ccaaagtttc aaatttaact ggcaaactag tatttttaac ttcaattact gtactattat
    10921 tttcctcaaa taaatttaca tgtacttcct tttttatagc actttgatag ttagttgctg
    10981 cttctattgc attatctatt agatttccta atatatctac aaattcataa tcctcaatag
    11041 gatatttagg gaaaggggta tagcagttgc aatttaattc tatattattt tgcctagctt
    11101 ttattttttt actgtataat atggcgctga tgatattatt acctgtgttt aataaaatat
    11161 catctgaatg taattgatat ccatcaataa ctgtatttag ataatcaagt agctcgttat
    11221 cttgactttt ttctgcgatt ccataaattg cattaagctg attttttata tcatgttgtt
    11281 ttgctctaac atcatctaac agattttcta atataggatt atattccatg tatatttcat
    11341 tagctttctg tttttgtttt atttgtaata attgtttgaa cactattgca actattaatg
    11401 tccatgttat tatacctaca ataataagcg aaatataatt cacactatta aaatctattt
    11461 tccaagatac gaaataaatt cctaaaggta tagctattaa aattattaac cattgaataa
    11521 tttttttaaa tctattatat aaagtaacta tctcgtttaa tgggatatat ctatatgtaa
    11581 atattgatat tactaataat attaaattgc atgatattgc aataaaatca ttctgtttaa
    11641 ttatccctaa caattgaaaa aggaagacaa tcattaattg aatacttaac aaataaatag
    11701 ttgctatagt atattcaaaa ataagtaatt taacagatat atctgtaatc aacttgaata
    11761 caagcaatat agcaattccc aacattactt cttttaaggg aatattaaaa tatataaata
    11821 aggtcacaat aataatatgt aatacaatta atataacttt atacatggga cctttcaaaa
    11881 ataatctctt atctatcttg ctaagcacta atatcaaact agtgatttcc aatatattca
    11941 taataataaa atagacaaac tccatattat atcccccctt caatcctatt aatcacatct
    12001 acactatact tgtctccaat aagtgctacc tcttcataat catagaaatt gatatcccaa
    12061 gcttttttat tatgtttttc tatacttctt atatgattaa tgttaactac ataacttcta
    12121 tgagtcctaa caaaataatc aactcctgtt tcttgaagca tctcaatcat ttgtttgaat
    12181 gtcatacttg gaattactat tttacccaga gtagtatgca gataaagctt tcttctacat
    12241 gactctgcat aaaatatatc attgactgat actttatgaa taacattctt cagctttatg
    12301 gtgatatact ttttatctac tttattttct ttatttactt tgttgattcc tttcaataat
    12361 ttgttggtca catcaattat tttacttttc gtgaaaggtt tttcaataaa atcataacaa
    12421 tgatattctt gaactgcttt tggcaaatac attaaatgtg tggtaataaa aataatatag
    12481 gacagctcat attgttctat agatcttatg atctcagcta tttttaaccc acttatgtct
    12541 ggcagctgaa tatctaagaa aaatagatcc attcttatct ctttcaataa cttgagagct
    12601 gttttacctg tccctgcttt ataaattctt acatcgctaa aattagtctt caaaacatat
    12661 tccaaattat ttcttgatgt atcattgtct tcaactataa gtatgttatt catctaatca
    12721 tcccctatac aatgaataaa gttcttatat taatctcgaa tactattatt atacctaaat
    12781 atcttaataa ttggtatata tttccacaaa aaaggcataa aaaaaaatgg attatgaatc
    12841 catattaatt tcaaaaagat agtagacttt catacttgtc caacaattaa gttattaata
    12901 tttataatat ctgctaaggg aaagatatta tttttttaaa actcttttat cttaagcatg
    12961 aaagtccttt tttaaaatta atcatttttt cttaattttt caggaacttt tggttggtta
    13021 aagaaccata tgcatgctgt ttgaacagaa agtgaagcta ctgcaatgcc aatcaatcct
    13081 actaaaccta ataactttgt tgatactttc tcgttaattg ttgctaacat attttgacct
    13141 cgctttcctt tttatttatt attggtagaa ctgttagtga ctccatgaat acggcaatag
    13201 cagctaccat ataatacgac tctaatgaat tcaaaaatat gctcatggct attataatta
    13261 ttgattgtac aataaccgta atcatacttt tctttttgta agctactttt tctgagctgc
    13321 ccaggggctt attgactgtg tcaacaggtg cataagtgat aattattatg catgattcaa
    13381 ttagcactaa tataattatt ataagatttt tatcaaaatc taatagtaaa tgtgaaatca
    13441 aaattgctaa aaaacatgat agcaaaaaat atataaaaca tttccaatgt gattttgcat
    13501 gatatcctcc agcttgtacc ctaagtgaac aaaaaaacaa tataaatact atgactttta
    13561 acaaacacct gaaaatgatt cctaagataa ccataccaat aaggattaaa agtgatgata
    13621 ttataatttc aaatccatat gtataaactt ctttatcatc ttctttaata attttcttac
    13681 caattagttt gctagaaatt ttgtttgaaa attcatatat cacaaatatc ctcctctcac
    13741 atttttaatt ttatactaat tccagtacaa atcaacccat atatgacttt tggtagttaa
    13801 ctcgtgatat ttggtcatta tttaattaag ttctccatta tacaacatta tattaacgct
    13861 aaaataatct ttaatgcaca taatctccat attaccgtaa tatttttcta ctatttgatt
    13921 tatgttcata agtcctatac catgtatttc tttatcttcc tttgtggtat caaggcttat
    13981 attttcgctg cctatagtgc tattaacaca gtcaatgaca agataattat ttacattatt
    14041 gatgtctaac ttgatatatc tattgttttc atcaacctta acagtagcct caatagcatt
    14101 atcaatgaga ttacctaata tgatacatat atctactgta tcaatagtca gattatctac
    14161 acttcctatg ttcattacac aatttatatt attgttccca gctctagcat atttcctatt
    14221 caataatgca gatattgctg gatattttgt aataattatt ttatctacct catcaatttg
    14281 cgacaacaat ttattaagat actcttccag tttggtatat tctttgtatc tgagtaatcc
    14341 ttttatattc ccgagatgat tagacatatc atgtctcaag ctttttaact tgagagttgc
    14401 attattgatt tcatcaaagt attttgactg catctcatat tgttgaattt tcaattgtaa
    14461 ttccaagtcc ttctttgatt gagccaataa cttgtcatat ataagcaaag atactatatt
    14521 gacaatacct aatcctaata ttacgaatcc agccactata ctgtcttcat tattttcata
    14581 catgaggttc ctatacatag gcacaatact tatcattatg cctagattaa taataaatag
    14641 tgtaataatc tctattaaca aacttttctt caagaaacgt agtccaaatc tttccccatc
    14701 agatataaaa agtacaataa ccaaaaaagt tattaacttg gacaccacca tacctaatac
    14761 tcttaaaatg ttgcttttgg caaaaacagc tggtgattct ccaaaaataa agcttaaaag
    14821 ggaaagtatt atcccttcaa tggcaacaat taatattaat aatcctatgt accctaataa
    14881 taatttcatt attttttcat catataatgc taaaactaca acaaacataa tgattatcat
    14941 acctagaaag gaacctctga aagtacaatc taaatcatag gaaaaataat tgaaaataaa
    15001 tattatagct gttattgaaa aaccccctac ataataagca attatactat tgtatctttt
    15061 cttataaaca gagctgcaaa attttattat tatcaaagct tccactatat caacaaataa
    15121 ttctataaga taccaaatca taacttcacc cttttccgac ttaaaaaagt ctcttttact
    15181 tcttttgcat ttcttctact tactggaatt ctcttaccat ttttaagtag tacctctttg
    15241 gatgtaatta attctatctt gtcaatattt gctatgtaac cttgatgtac tctaataaat
    15301 ttatcttcat taagcaacat gttcaactcg ttgaaggttc cgtaaaactc tatattctgg
    15361 ttatccgcca tcaccatgac tttatttttg tatttctcaa aataatttat gctgttgtaa
    15421 gcaattataa tcttttcctt attcttgttt atcactaaaa actcttcttc tttttgaggt
    15481 tctttcaatt catctattaa cttaatagca tcaaataatg ctttttgaaa ctgttcaatc
    15541 ttaactggct taagaatata cctaaaagta ttgacttcaa aaacatcaaa tacatactct
    15601 ttatatcccg ttacaaatat aatgatcaca ttgtcattta tttctctaat ctttctagct
    15661 gattcaatac catctaatcc tttcatttcc atatccaaga atatgatatg aagtttattg
    15721 gaattacaat atgtaatcag atcttctcca cataagaact tcaaaatatt aaccttaata
    15781 ttttttgtct ctattgcttc cataatcaat ttttctacta aattcacctg taaaatctcg
    15841 tcatcacata tagcaatatt aaacttcatt attaaatcct ccataattta ttaactttaa
    15901 gttatctgta tatataaaac taacaattat gcaacgtcat ctaatgactt ttcttaaatt
    15961 tattaagttg attcgtataa ataattagca ttattagggt caaatattat atataactta
    16021 tatattttaa atttacagat aataatatat aaataaatta tacctaatgt tacaaatttt
    16081 tgtcaataca cacataacaa tttataaatt tcttaattat gagtttttat tacataacca
    16141 aagtttattt gtcatattat tacattaata ggaaataaag taattatggt agtatataaa
    16201 aaaactagtt aaggtattta actacccaac tagttttata tttgttaatc aacttttatt
    16261 acattatcaa cattatctat tgtatgtttt agatatccta agaaatcatc tcttaattca
    16321 tctcttctaa gagcagattc cactgtagct tgtaaaaatc ccattatatt tcctacatca
    16381 tatctcttgc ctataaagtc atatgcatat attgcttcat ctcttgctaa gcgtttaaga
    16441 gaatcagtca actgaatctc accgcctgcc cctgcttctt gggtttccaa gtatttaaag
    16501 atgcttggac taataatata tcttcctaat atagctatgt tagatggtgc atcttcgctt
    16561 aatggttttt ctacaaggtc ttttatttta tatatcctat cttctatatg tttagcatca
    16621 atgataccat acttggacac gtcatcaata ggtactttct gaactcctaa tattgatgtt
    16681 ctatattcac tgtacacatc aatcatttgc tgcaagcatg gtttttttga tacaattaca
    16741 tcatcaccta acaatactgc aaatggttca ttaccaataa aatgtttcgc cattagtatt
    16801 gcatgaccta atcctcttgg ctctttttgc ctaatgtaat gaatattagc tatctctgaa
    16861 acacttctag caatctccaa caaatcatct ttaccctttt tctccagctc caattcaagt
    16921 tcaatagatt tgtcaaaatg atcttctata gaacgtttat ttctaccagt aacaataatt
    16981 atatcttgta cacctgatga aacagcttcc tccacaatat attgaatagt tggtttgtca
    17041 actataggta acatctcttt tggctgagcc tttgtagctg gtaaaaaccg agtacctaga
    17101 cctgccgctg gaataatcgc ctttctaatc ttcatctaca ttttctcctc cttaaatata
    17161 ttaactatat taactaagtt cttcattctc tatttctaca ttcttatcat ccatcaatac
    17221 tactctatca gatttagcgt tttttactgt tattgtaaaa gtattgaccc ccattgacat
    17281 atgattgatg ctcagatcat aggaaacatt aatctccatg aaatcttctt ctctctcaac
    17341 atttattttt tttgtatggg tatttatttc aaaaatacca tatggggtct gatagtgtgt
    17401 aatgtgtgtt ttgtcttttt caaataccat atgagaattg actccaccaa atctcaatat
    17461 ggaaatttga tctttctcat gctttatggt tgttttagtt tctttatcac catcaattgt
    17521 tgaatctata taggttatat aaaccttatt attcttttca acatagctac ctgttgtcac
    17581 taattctatt tcatctgatt caaacatatc tgtctgaaca ccttttactc ttaccaatac
    17641 gtcttttgtc actctatttc acctcattaa agttcttact tattaaatgc aaattcaata
    17701 agtctatcca ctaattcttc gttagacatt cctttatctt cccaaagcat tggatacatg
    17761 cttatacttg tgaatcctgg caatgtattt atttcattga aaacaacttc acctgattct
    17821 tcttctataa agaaatcagc tcttgctagt cctctaccat caaccgctct aaaaatctgc
    17881 tctgcacaat ctctgatttt tttgagggtt atcttaggta catctggatt aattattgtt
    17941 ttagaaccta tatcattata ttttgaatcg taatcgtaga attcagctgc tgaaattatt
    18001 tcaccaacat tagatgttct tggatggtaa ttaccaagta cagcacattc aacttctcta
    18061 cctactatgg tttcttctat caaaagtttt gaatcatgct tgattgcaag ttcaagacca
    18121 tcaaataatt ctcctctgtt atgtgccttg gtaatacctt tagatgaacc ggcattagat
    18181 ggttttacaa agactggata ttccaattgt ctttctatct tagccactac ttctttaata
    18241 tcatccattt cttttttata tactggaacg tatttagcct gtctaattcc taatctatca
    18301 actatgactt tcgtgaaaag cttatccata gatacactag aagctaaaat accacaacct
    18361 acatacggga taccagcaag ttccaataaa ccttgaacac ttccatcttc tccatacagc
    18421 ccgtgaagtg ccgggaacac tatatcaaca tctactttta ctattccatc ttccttgaaa
    18481 attattaatg atttatcagt cgcatcggga ctaatgatag cattatccga attgcccacc
    18541 caactatcta ctgttaaatc ttctatcttt ccatgatata ttctccagtt accttctttt
    18601 gttattccta caggatatat attatattta tctttattga tgtttttcat tatagttact
    18661 gctgatatac atgatatctc atgttcggat gattgtccac caaataaaac aacaatattt
    18721 ctcttattca tattatattc ctccccattt ttgaattatt cagaattaaa aatcagtaaa
    18781 tttttccatt atggataaat gtgtagttgt acaaactcat gtattattaa atatattaat
    18841 tatcatctcc aaatatgata aattacttat ctgttctatt ttatatctta ttgtattttt
    18901 attcaatagc taattatata aatattccat ggctcgcaac ttcacatacc tctttactcc
    18961 cttcgttagt acataatcta aaatgtgact atataaaaaa atcatatata atgataataa
    19021 cgaaagtaat tatcattata tatgattttc taatataacc gttgtcttaa tttctttttt
    19081 tctctaatcc ctattaacaa aaaccttact atcattatcc tgtctatctc tatctttatc
    19141 cctactaaaa ttaaaccact ccaaaaactt gaatctaatc tttataggca tatcctcttc
    19201 aggttctgcc attacaatag aatcatactc ttcatctgtc aaaacccttt taagagtctc
    19261 ttttgtctct tctggaacta ctccatgtgt tacatcaaca aagcataaag gtggaaacat
    19321 gacacaccac caattcttac ctttcgcttc acctatctct accagcaaag cttcatattc
    19381 acctggaggt aatattatat ctccataagt cttcaatgga aattgttcca tcttcaactt
    19441 aacgtttata tcataatcat aattattttc ttctataact ctttcagcta ttctcttaat
    19501 ctcatctcta ttatcagtaa taagttgtct tgtttcttct atattttcag attcttccaa
    19561 aataccattc attctgtcta gaatctcatc tcttaccttc aatttcaatt tctgatcttc
    19621 ttcactatca ctatttgcaa tgacatgaaa acgtatcaaa ctatctgata taccctcaat
    19681 cacagcagca cttgtcccat ttttgccgta atcataaact atagctgcca acataagtat
    19741 cactattagt agtgacaata tataggttct taatatcctt ttcttttcaa atactttcat
    19801 tagattcacc ttcatcaatc ttcccccatc ttttcatatt tacaacctac tatttctatt
    19861 attaccagca tcagtattat ttatacataa tctatctgtt aaaccgtaaa ttagaaaaca
    19921 tgacaaaaag taaatgaata atgatttttt attttgaaag tcccactctt cttatattaa
    19981 ccttacattc tacttcaata gccgctgcat taaagaaatt ctgccagtct gatttagttg
    20041 tcttccatac ttttctatta ctggttttca agttgttata agcattgatg atatctatac
    20101 catactcttc ttgaataata ttcattaatt catatatgtc ctcttccata ctattagcta
    20161 cttcattttc aatctcagca atataacttg tactgaataa cttgtcttta tcttctagga
    20221 tatattctga tacatctcct tcactactta ttgaaatttt aatttttaac aatccatctt
    20281 ttaattcaaa atccattttt gatgttaaat cacttatttc ataaggcact aatacacctt
    20341 ccatatctac taaagcaaca gtttccttgc cctttccaag aatccagctg tatggtgtca
    20401 tgtatttatc ttccatccat cctctaagct gataatccct aaggatggct aatccatcta
    20461 caataacctc attatctctg aatattacat ttggcattac accatttcct tctgtactgt
    20521 acatttggga aataaaatct cctagctcaa tggtcttggc gcttatggtt tccaaactat
    20581 tatttataaa aacctgtgaa agatagatcc ctgttgtctc ttccccatta ggaactgatt
    20641 caagcaattt ttttcctgtt tccttggtac ctaataataa taaggctttg gaatattccg
    20701 gattcctgtc aaagtgatcc agaacttttc ttagattatg agggtcattc aaaaaatcag
    20761 ctccaaatat aattaccttg gtatgatcaa aattgattct aagattagat tttttaccaa
    20821 aagccctatt agcttgtgtc aaagtctctg ctttggtgac cttgatgaac tttgtagcct
    20881 caccaccact ctgagctgtt ataacaggca aattaggaat ggtatatgtt acctctaata
    20941 aatcaccaat atcatctagt gcaaggctta ttacatatgc tctgtcattt aattcaacct
    21001 tatcccagca acctactaga agtatagaac atataaccaa tatagccata actttaattt
    21061 tcatgttacc atcaacctct catcactttc atatattatt tgctggtttt acctaatcct
    21121 ctcatcttag caacaaccaa taagatcaat ggaataggca gaaggaataa taagctaaca
    21181 tatcgtgtca taatctctat ccatttataa gtctccacta tattatctgg tataagtgat
    21241 attagatata taataggtat tagaggcaaa atcaagaaat tctgttcttt caagttagca
    21301 atttttttaa ttaataatcc tgaaaagaat aaataagcgt ttataagcaa aaatactgtc
    21361 attatccaaa aacttaccat tagggcatct tgcctttgta ttaaagcacc tggcagatgt
    21421 attgtctgca tgatggtcat tacaggccat atttgtctgg aagtctctat aggtccaaaa
    21481 gagccaattg tcaaaatgca tattaaagca tttagtacac caacaaaagc tacacttcgt
    21541 aatgtcacct tgggtaattt atcaggattt attacataag gacttgatag caacaataac
    21601 tctatccctg aataggcaaa agacattatt aagcttccat agatgaattt ttctcctgaa
    21661 attgaaaaaa taggtgaaat attatataac ttgatatctg gaactgcgaa gaaaaatata
    21721 actaccaaag gaatcaatat aataaatatt aacagttctg ccattctagc tcttgcttca
    21781 taaccttttc ttgtcagata gactacaacc aaaagcatag ctattactat aatttctatc
    21841 ggtgtatttc ttagtaatgc ctgttttacc agttctccaa aaacccttat ttccagccct
    21901 gccaaaatta tgagttttag acagaataca actcctataa taatggcgat tggtttattg
    21961 aatatcagtt ctgtatattc tacaatgttc ttatcaggaa acattttaac aagagaagtt
    22021 ataatgaaaa catacacaag ggaaatgata gcaccgccta gaacaataaa atgaccatcg
    22081 ccatctgcta tttcagaagc gattctaggc aaaattaaac ttgtattact gaacatgttg
    22141 agaataatca gaatctcaac ttgtctcatt gatattttat tgttttgtga aaacattatt
    22201 ttctcctttt tcatctatat ctaatcttac tttattactt cttttagcaa ataccggtct
    22261 tagtttatta agaaatattg gcatccttat tagagaatcc tgaagatcct cattattggt
    22321 ttctcttgca acataaggtg aaagataagg tatatttata ctcttaagtg atacaagatg
    22381 agtcaatatt attaagatac ctaaccaaaa accaaggaaa cctaagaaag ccgataataa
    22441 tataattagg tattttatta tcctaaaggc tgatgtaagt gaataactgg gaatagcaaa
    22501 tgaggatata gctgtcaatg ccacgataat tactataata gggcttacta gattagcttc
    22561 tactactgcc tgaccgacta ttaaacctcc aactattcca atagtattac ctataggtgc
    22621 tggaagcctc actcctgcct ctctcaaaag ttcaaaagcc agttccatta tcagcacttc
    22681 aatcaatgca ggaaacggca cgccttccct agcagccgca atggaaaatg ttaacgatgt
    22741 tggtatcatg gcaggatgga aggtagttaa tgccagatag aatcctggta tagcaaaaga
    22801 taaaaatgca gcacaatatc ttagaaatct cacaaagctc atcacatacc atctttgata
    22861 ataatcctct gatgattgaa aaaaacaatt aagggttgta ggcagcaaaa gaacaaaggg
    22921 tgtattgtct acaactatag ctactcttcc ctccaatatt gcagatgcca ctttgtccgg
    22981 tctctgagtt acttgggatt gaggaaatgg agaataccaa ttagtttcta tcaattgttc
    23041 taatgtacca ctttccaata cactatctat cttaaaataa ctgagtcttt cttctatttc
    23101 ttgtaatacc tgaggtctta caagatcatc taaatacata agagccacat cggttcttgt
    23161 tcttgttcct aattgtatct gtttaacttt taatttacta tctctgatac gtcttctaat
    23221 tagtactgta ttgattcgaa atgcctctgt aaagccttcc ttagagcctc ttattacatt
    23281 ctctgtatct ggctgttgta cacctctgtt gggaaatcct tttgtggcta ctactattgc
    23341 tttttcataa ccatcaataa aaattacagt atctcccgat agtacggcta atactgcatc
    23401 atccattata ttaatttctt tcaaatctgc tgttgcgaac ccaccatctt taatgaatga
    23461 gaacttgtct tcatccgttt ctggaagact ctttccaaca ccccttactt gaactaatag
    23521 ttgttcaaga acagattctt ctatgaccct tctgtcggtc ataacatcaa tgtatgcaat
    23581 atatgcccat acatctttgt ttttacctat agggaatttt ctttttacca aatcaccaca
    23641 atcagtaaat agttcttcaa aatttcttat attggtatct attaaatctg aaaatggaat
    23701 tatgaccttg ttgcttcttt cat
//
