LOCUS       NZ_CP047645            21612 bp    DNA     circular CON 23-JUN-2024
DEFINITION  Bacillus subtilis strain PMB102 chromosome.
ACCESSION   NZ_CP047645
VERSION     NZ_CP047645.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4103088)
  AUTHORS   Wu,J.-J., Huang,J.-W. and Deng,W.-L.
  TITLE     Bacillus subtilis PMB102 suppresses Alternaria leaf spot on Chinese
            cabbage
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4103088)
  AUTHORS   Wu,J.-J., Huang,J.-W. and Deng,W.-L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2020) PhD program in microbial genomics, National
            Chung Hsing University and Academia Sinica, No. 145, Xingda Rd.,
            Taichung 40227, Taiwan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-JAN-2019
            Assembly Method                   :: Canu v. 1.8; Pilon v. 1.23
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.97x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina GAIIx
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018141065.1-RS_2024_06_23
            Annotation Date                   :: 06/23/2024 04:52:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,262
            CDSs (total)                      :: 4,141
            Genes (coding)                    :: 3,965
            CDSs (with protein)               :: 3,965
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 121 of 176
            Pseudo Genes (incomplete)         :: 64 of 176
            Pseudo Genes (internal stop)      :: 21 of 176
            Pseudo Genes (multiple problems)  :: 27 of 176
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:29:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3720652
            Orig. end                         :: 3742264
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047645.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Ph.D. Program in Microbial
            Genomics, National Chung Hsing University and Academia Sinica, No.
            145, Xingda Rd., Taichung 40227, Taiwan.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="10"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(111..125)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(203..3889)
                     /gene="narG"
                     /locus_tag="GSN02_RS19230"
                     /old_locus_tag="GSN02_19235"
     CDS             complement(203..3889)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="narG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="GSN02_RS19230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19235"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_103804118.1"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQEHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRQTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAETPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMELVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3955..3970)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3979..3992)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3979..3993
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     gene            complement(4085..4561)
                     /gene="arfM"
                     /locus_tag="GSN02_RS19235"
                     /old_locus_tag="GSN02_19240"
     CDS             complement(4085..4561)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="GSN02_RS19235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19240"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_014478284.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDSRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(4619..4634)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4705..5424
                     /gene="ywiC"
                     /locus_tag="GSN02_RS19240"
                     /old_locus_tag="GSN02_19245"
     CDS             4705..5424
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="GSN02_RS19240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19245"
                     /product="YwiC-like family protein"
                     /protein_id="WP_021480832.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMAKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRTFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFFAVMCLFMTR"
     gene            complement(5456..6172)
                     /gene="fnr"
                     /locus_tag="GSN02_RS19245"
                     /old_locus_tag="GSN02_19250"
     CDS             complement(5456..6172)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="GSN02_RS19245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19250"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_014481215.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESINRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6271..7457)
                     /gene="narK"
                     /locus_tag="GSN02_RS19250"
                     /old_locus_tag="GSN02_19255"
                     /pseudo=""
     CDS             complement(6271..7457)
                     /codon_start=1
                     /gene="narK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="GSN02_RS19250"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19255"
                     /product="nitrate transporter NarK"
                     /pseudo=""
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPFGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFS
                     "
     misc_feature    complement(7522..7537)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="GSN02_RS19255"
                     /old_locus_tag="GSN02_19260"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="GSN02_RS19255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19260"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_021480835.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELDKLRKDLENFRVPFDVWYSETSLYQNGKIDTALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEELGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /gene="ywiB"
                     /locus_tag="GSN02_RS19260"
                     /old_locus_tag="GSN02_19265"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="GSN02_RS19260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19265"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_003243604.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="GSN02_RS19265"
                     /old_locus_tag="GSN02_19270"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="GSN02_RS19265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19270"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 9e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="GSN02_RS19265_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="GSN02_RS19265_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="GSN02_RS19270"
                     /old_locus_tag="GSN02_19275"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="GSN02_RS19270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19275"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="GSN02_RS19275"
                     /old_locus_tag="GSN02_19280"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="GSN02_RS19275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19280"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_015714887.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.7, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.1e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.3e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.1e-44, bitscore:
                     150.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.5e-06, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.3e-22, bitscore: 76.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.2e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKAYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GSN02_RS19275_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="GSN02_RS19275"
                     /locus_tag="GSN02_RS19275"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="GSN02_RS19280"
                     /old_locus_tag="GSN02_19285"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="GSN02_RS19280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19285"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /gene="albC"
                     /locus_tag="GSN02_RS19285"
                     /old_locus_tag="GSN02_19290"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="GSN02_RS19285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19290"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003227564.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13804
                     /gene="albD"
                     /locus_tag="GSN02_RS19290"
                     /old_locus_tag="GSN02_19295"
                     /pseudo=""
     CDS             12495..13804
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="GSN02_RS19290"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19295"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     WMFLLHAAIFACVCISAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAVFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGALSG"
     gene            13794..14954
                     /gene="albE"
                     /locus_tag="GSN02_RS19295"
                     /old_locus_tag="GSN02_19300"
     CDS             13794..14954
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="GSN02_RS19295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19300"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_077671151.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 4.3e-05,
                     bitscore: 21.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRRDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14959..16239
                     /gene="albF"
                     /locus_tag="GSN02_RS19300"
                     /old_locus_tag="GSN02_19305"
     CDS             14959..16239
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="GSN02_RS19300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19305"
                     /product="pitrilysin family protein"
                     /protein_id="WP_041850411.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.5e-13, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDINDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16236..16937
                     /gene="albG"
                     /locus_tag="GSN02_RS19305"
                     /old_locus_tag="GSN02_19310"
     CDS             16236..16937
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="GSN02_RS19305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19310"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_046160959.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILAAIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(16943..18319)
                     /gene="ywhL"
                     /locus_tag="GSN02_RS19310"
                     /old_locus_tag="GSN02_19315"
     CDS             complement(16943..18319)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="GSN02_RS19310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19315"
                     /product="YncE family protein"
                     /protein_id="WP_014481223.1"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSAVPTNLGVTFDKAFTYILHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLMTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     misc_feature    18286..18303
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18358..19713)
                     /gene="ywhK"
                     /locus_tag="GSN02_RS19315"
                     /old_locus_tag="GSN02_19320"
     CDS             complement(18358..19713)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="GSN02_RS19315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19320"
                     /product="YncE family protein"
                     /protein_id="WP_049140945.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSVETVISLGVSPGAITI"
     gene            complement(19710..19940)
                     /locus_tag="GSN02_RS21435"
                     /old_locus_tag="GSN02_19325"
                     /pseudo=""
     CDS             complement(19710..19940)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="GSN02_RS21435"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19325"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSV
                     YPQ"
     misc_feature    19894..19910
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19943..21088
                     /gene="rapF"
                     /locus_tag="GSN02_RS19320"
                     /old_locus_tag="GSN02_19330"
     CDS             19943..21088
                     /codon_start=1
                     /gene="rapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="GSN02_RS19320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19330"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_212082561.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFNFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     gene            21072..21191
                     /gene="phrF"
                     /locus_tag="GSN02_RS19325"
                     /old_locus_tag="GSN02_19335"
     CDS             21072..21191
                     /codon_start=1
                     /gene="phrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391627.1"
                     /locus_tag="GSN02_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GSN02_19335"
                     /product="phosphatase RapF inhibitor PhrF"
                     /protein_id="WP_009968329.1"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
ORIGIN
        1 tccttttttc aatgtccagc cgcctttata tttgtcctgg tcctcccatt gcttcgggta
       61 gccgatgccc ggctttgttt ctacattatt gaagtacata tattccgcac cggaacggtt
      121 tgtccacgtg tttttgcagg tgacgctgca cgtgtggcag ccgatgcatt tatccaagtt
      181 catgaccata ccgatttgcg ctttaatctt caagccaatc gacctccttc agcttgcgga
      241 tgacgacgtt caggtcgcgc tgattccccg ttggaccgta ataattaaag ccgtagctga
      301 gctgggcgta gccaccgatc atctgtgtcg gcttgacgtg aatccttgtc gggctgttat
      361 gggtgcctcc gcggttattc gttagctttg tgcctggcac gttgatgtgg cggtcctggg
      421 catggtgcat aaacgccatt cctttaggaa tccgatgaga caaaaccgct cttgcgacga
      481 caacgccgtt tcggttgaag cattcaatcc aatcgttgtc tttgatatcc gtatcctctg
      541 catcatcttt attcatccat acggtcggtc cgccgcggaa cagcgtcagc atcggcaggg
      601 aatcaaaata catgctgtgg acagaccatt tattatgcgg cgtcaaataa ttaaggacga
      661 tttcttttcc ctcttgatca ggccgcttgc tcagaaacgg gcgatgctgg aggatcggtt
      721 tgaatgtcgc catcgtttca ccgaattcca tcatcagttc atgatcgaca taataggatt
      781 gtctgcctgt cagcgtccgc cacggaatta atttttcaac attcgttgta aacggcgaat
      841 acctgcgccc tcctttttca gagccggaaa acgctggaga cgtgatcacc gttttcggct
      901 gggctgtaat ttgttcgaac gtaaagcatt cttcctcgcg ttcttccgcc aggtctttca
      961 gcttcaggtt cgtgatgttt tcaagtgatt cccatgcttt gacggcgacc tttccattcg
     1021 aagtggatga tagggttaaa atcgcttctg ctgcctgctt tgcttcactt atatttggac
     1081 atccctttgc gacactgtcc gaggtgattt ctcccaatct ctgtttgagt gattcatatt
     1141 catcggctat tgaccagctc atcccttttg ttccgctcgg ctttaaagca acgttcggac
     1201 caagtgcagt cattttatga aaaatgtgtt tgtaatcccg ttcaacgact tggatgttcg
     1261 gcatcgtttt tcccggaatg gcttcacatt cgcctttgct ccagtcattg attttgccga
     1321 atggctgggc caattcctgc atggtgtcat ggaggagcgg cgtcgcaacc acttctttca
     1381 cgagctccat atcgacttct tctgccagat cggaaacggc ttttgacagc gccttgaaaa
     1441 tatcccagtc tgacttcgat tcccacggag ccgagatcgc aggagcaaat ggatgaatga
     1501 acggatgcat atctgtgctg ctgagatcgt gtttttcata ccatgtcgcc gccggcagca
     1561 cgatatcgga atacagcgcc gtaccggcca ttcggaagtc aagattgatt aacaagtcga
     1621 gctttccttc cggcgcctgc tcccgccatt tgatttcttc agggcggatg ctgtcgctgt
     1681 cgtcattcat caagccgttt gtcgtcccta acaaatgctt gagaaaatat tcatgccctt
     1741 ttcctgagct cgagatcaga tttgcccgcc atacgaagag atttcttggg aaattcactt
     1801 cattatcagg atcttcaatc gcgaatttca gttttttctc ttggagctgt gaggccacgt
     1861 acgcaccaac gtcttcaggt gtttctgccc ctgctttttc agcttcttta tacagatcga
     1921 tgccattttg attgaaagtc gggtaagacg gaagccaccc cagccgcgcg gccagcacat
     1981 tgtaatcagc gtggtgcttg tagcgggatg acgcagcaat cggcgatgcc aaatcactga
     2041 tcggctggtc ctcataacgc cactgatctg tcgcaaagta gaaaaatgag gtgccgtttt
     2101 gcagcttggg cacgccttcc cagtcctttg cagttgcaat ggtctgccac ccttcagcag
     2161 gtcggagctt ttcctgcccc acgtaatggg cccagcctcc gccgtttacg ccttgggcgc
     2221 ctacaagtaa aacaagattt aacaccgctc ggtagatcgt gtcggagttg aaccagtggt
     2281 taatgccggc ccctacgata atcatggatc ggccgtctgt atcgatcgca ttttgggcaa
     2341 actctctggc aatcttaacg acagcttctt ttttgattcc tgtcatttgt tcctgccagg
     2401 caggcgtaaa cggctcagga tcatcatagg agacagccga tcgttcgccg atgccccggt
     2461 tcacgccgta gttagccagt atcaagtcaa acacggtcgt gatgtacgtt tcttcaccgt
     2521 tcaggttcat ttttttaata ggaagatccc gctcgagcac tttgtttccg tcatttgaaa
     2581 aatacgggat gcgcaccgtg ccgatttcgt cctctattcc cagcacagag agacggggtt
     2641 caatcggttc cccggtttct tcatcaatca tgtgcaggtt ccatttctgc tgcccgtccc
     2701 agcgcgatcc cattgtccct tggggtatgg caaatgaact tgtttgttca tcccaaaccg
     2761 caggcttcca ctgatcatgc tttgtctgcc gcccgatgtc cttcgcatgc agaaaccgtc
     2821 ccgctgtgta tacgccattt tcttttgaca gggtgacgag aaatggaaaa tcagtgtatt
     2881 gcttcgcgta ctcaataaaa cgttcagttt cttggttcac gtaaaattcc tgcagaatga
     2941 catgacccat cgccatcgca agtgccccgt cagtcccttg gcgaatactc agccagtcat
     3001 ccgcgaactt tgaggattcc gcaaaatccg gactgatcga aatgacctta gcgcctttat
     3061 agcgggcctc cgccaaaaaa tgcgcgtcag gcgttctcgt taacggaacg ttggagcccc
     3121 atgtgatgat atagccggaa ttgtaccaat cactgctttc cggaacgtcc gtctggtcac
     3181 cccaaatttg cggggatgct ggtggaagat ccgcatacca gtcataaaaa ctgagcatag
     3241 ggcctccgat taacgacata aaccgggagc ctgatgcatg gctgatcatg gacatggccg
     3301 gaatcggaga aaaaccgacg tttcggtcag gcccatattt catcactgta tacagcagag
     3361 aggctgaaat cagcttcagc acctccggcc attcagcgcg cacaaaaccg cctttccctc
     3421 tcgcctgttt ataggacttc gctttttcag ggttttcgac gatcgatttc caggcttcca
     3481 atggattttg atgttcttgc agtgcctccc gccataaatt aatcagtaca ccgcgcacgt
     3541 atggatattt cacacgcagc gggctgtaga tataccatga aaaactggcc ccccgcgggc
     3601 agcctctcgg ttcaaaatca ggcatatccg gtcctgttga tggataattc aaattttgcc
     3661 cttcccacgt gacaattccg ttttttacat aaatattcca gctgcaagac cctgtacagt
     3721 taacgccgtg ggtggagcga acgactttgt cgtactgcca tctgtttctg tatacattct
     3781 cccaatcgcg atcttcgcgg gtggtttggc tatgtttatt tgaatggtgt tcgataggag
     3841 agaaataatt caatctccta aacaacggac tccttttctt tttcttcatg agagttcact
     3901 ccttccgagt caggtgatgc taagttcact ataaacagag acagcgtgtt tccttgtgaa
     3961 ctatgtcaca cactctgctt ttttcacaaa atgttcacac aaaggagaag gaaggctgcg
     4021 ttcaggcaga acgcttgggt cattagccgc ctttcattca aagatcaaaa aaaaccggct
     4081 ctatttaaga accgggctca gcgttttcat cctgtgatgt atgcagatac cgcaaaaata
     4141 attgatagga acaaaaaaca ttttgctgaa gcatagccaa aaagttcatt tgcagctgcg
     4201 gatggtaaga catcattttc ttaaatatgt aatatgggat attgagaatc agaatgtctg
     4261 aagtggcatt gactgagata aagggcgata aataaagccc gcctttttca tcaatcggaa
     4321 acacatcgcc tttttcccac agcgcaacgg ttttcgaccc ttcagggagc ctgctgtcca
     4381 tgaaacggac actgcctttt aatacaatat agacagattg agaatgaaga aaagatggag
     4441 actgatcaca tgagccgcgg ataaacgtgc cgtttttcag caaggtttcg acaatggata
     4501 gaggcacttc attaaacata ggaagttgtt tcagaaataa taaatagtca cactgattca
     4561 taggaaaacc tcctgtgcta aggatagctt tagtgtagct cgactgagcc tgtacagcag
     4621 tgatgtattt cacagcctgt atgatgaatg tcacttatca ggagggtgac tgcatttata
     4681 atgaaagaaa aaaggaggat ttcgatgaag gcgctgattc cgaagcagca cggcgcgtgg
     4741 gcgatgctgc tgatcccatt tttactcggc atggccaagg gaggccccgt tatttggcat
     4801 attccgctct tcctaggctg gcttttccta tacttagcgg tttatcccgt tacgcttgcc
     4861 ttaaaaaaga aacaaagcaa accatatcaa aagtggatgt gttattacgg ttttcccgcc
     4921 tgctgctttt tgatgatctc ggtctttcat aagccgcctc tcatctgggt gggcgtttct
     4981 ttactgccgc tgtttctcat acatatgtat tttgcccgca gaaaaaacga acgagcccta
     5041 ttgaatgatg ttgcaggtgt cttgttcttt tgttcgggcg ggtttgcgag ctgctggctg
     5101 gggatgggaa ccctcgacgg ctgggcttgg tttattttct tgcagtctgc tttatttttt
     5161 atcgggagtt ccttttatgt gaaatcggtg attcgtgaaa gaaaaaacag gacatttgca
     5221 tactggtcat ggggatatca cctgctgctc ccctttttat ccgctctttt tggagcagga
     5281 tgggcgtttc tcgcttttat cccgagcagc ttgcgggcat ggttttttca tggaagggat
     5341 tggcccgtaa aaacgattgg cattctggaa atcgtgaatg cctgcttctt ttttgccgtc
     5401 atgtgcctct ttatgacaag gtaaaaaaac aaggacaccg ctgtccttgt ttttttcagt
     5461 caatattgca aatctccagc gggcaatttt cacactcaat ctcacatcgt aaatagtccc
     5521 gcttgtgtaa aataattttt ccggattcgt ctatcgaaat aacccctttt ttgcggagat
     5581 ctcccagcat acggttgatg ctttcccgtg cagccgcaca aaactttgcc aaatcctgat
     5641 ttgtcaggac aatgttaatc agaatgccgt cgcttcgctc cactccgtag ctgtttgata
     5701 agcggataag ggtagaatag agcgccccct ttttgccatg aagaagcaga tccctgattt
     5761 tggactgaat cttccggagg tgcgtgctca tccatttcat gaactcaaat gtcaaagcgc
     5821 cgttttggat taattctttt tccagcttat ttttattaat gacgagcacc tcgccatcct
     5881 ctagcacttt tgcactgagc atataccttg gttcttcagt gaaaagtgtt aattctccga
     5941 cgatatcatg cttttggcag attctaagcg tcaggtcttt tccatcagat gtcagcttgc
     6001 cgatttcaat gagtcctgat tgaatcagat aaagctcttc tgcatccatt ccttctcgaa
     6061 acaaatacgt gtgtttttcc atttttcttt tcgtgctgat cgattccagc aattcatgca
     6121 gatcgctgga aataagatca ctatcagatg gtcgaacaga gagaaaattc atgagctcac
     6181 ctcgaagaaa gtcacgttgt gtgtttattg taacgtgaat tgatttgtac ccatcgagaa
     6241 aaaactaaca atcttgtgaa tgccccagtg ttagttgatg ctctggctgt ttctctccgt
     6301 gtgtgttttc attctttcct gccaatacat ccatatgaca aggacaaagc tggctaacgc
     6361 cacctctgaa agcgccataa acccgatcga gtactggcct gttgcctgaa acacactcgc
     6421 caatatgagc ggaggaaaaa agccgcctaa tccgcccatg gcagacacaa tcccattggc
     6481 aatccccgct tgcttcgaaa aatagaatgg caccagttta aaaacagtcc cgtttcctat
     6541 gcctgagcag acggccacgg ttaatgatcc aaacgtataa aggccaattg tcggcgagaa
     6601 cgataggata atgcctgata atgtaagccc agcaaaaaca aacatcaaga tgcggagcgg
     6661 gctcatttta tcagccagga atccgcccgc aggcctgagc agcgtagaaa ccgcaataaa
     6721 gccagccgtc cgcaagccgg catctgcagg attcagccca aaatgctcga ccagaaagtt
     6781 cggcagatag atagtgaagg cgacaaaggc accgaacgta ataaaataaa acaggctcag
     6841 aaaccatagc acatgatttc ggtaaacggc tttgatttga gtcttaacag aaactttgac
     6901 cttcttctca tgcctgtcgc cgaacaaaac gtgcagtaag gcaaagacag ccagcaaaac
     6961 cagatacatc tgcacggttg atttccaccc gacggcttga gcgataaccg gcgctgcaaa
     7021 tgtcgtaacg gctgtcccga tatttcctgc accgtaaatc ccattgacga caccgtgctt
     7081 ttctttcgga taatatttcg ggagggaggt cactccaatg gaaaacaccg ctcccccgat
     7141 ccctaagaaa agccgcctgc gattaaatca aacagagagt ccgcgatact gatccaaaat
     7201 acaggaaata aaagcaggat gaagctgacc ataaacatga gccgcgcgcc aaacctgttc
     7261 gttaaatacc caaaaggaat gcggagaagc gacccgagga tcacaggaat cgccgtcacc
     7321 aaagaaatct cacccttgct taaatgaata tctaatgtga tttgggaaat gagtgatgaa
     7381 atcagcaccc aaaccataaa ccctgccacc aagcttaatg actgtaacga taattgaatg
     7441 tgttgacggt tgatcatttg gcttgcccct ttcaatgatt caataatcag tcttatcata
     7501 caaaaactcg gcaaacagga ttgtgaatta catcacacgt ttttctcata aaaaaaggac
     7561 aaagcccgaa gactttgccc ttttgatcgt gattacattt tttccggagc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggctcttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagtttgtg acacggtgcg gaattcgttt ttccgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagtc ccagctcttc cccttggcga
     7921 agcatgctgc aaatacgggc atgcgcatat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ccgcacttcg cattgcaaag
     8041 aagtaacgaa cggcatccaa gccgacttct tcaatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatag cccagcgctt cgattgccgc tttcatacga
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agcaggtacg tgtacgtgcc gtccttctta
     8341 atcaatacgc ggtctttatc atcgccgaac gtcgtggaac ggaaccaagt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccgtgtcgat ttttccattt
     8461 tggtacagtg aagtttcgga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgaagct tgtccagctc atatttcagg ccgtattcac ggaaaaacgc gaggcgttca
     8581 ctttcctctt cgttaacgaa acggtcaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct cgccgcggta gccatcctcc ggcatcggtt tttccaatcc gagcgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc ctcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg tttgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatat tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gcctttcctt tatcaaaatg agcgacaatc
     9061 tcttcagcga tttgacgcgg cgcttttttt gccactcttg ccagctgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttga tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt tcttttcaca
     9901 tttttttcaa attatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtt attcagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggaag caatgaattt ccgatgccgc
    10621 tccacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagtt tggagctttt gaaggcttac aagcaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcgga gcgaaggcgt tctcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattgtccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtaattgat gagtttaaag atttgattcc gattattcct tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcaa gcaccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc gaaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggttgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 caggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtc ttttatcaga aaatgcgtga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcca ttcttcacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 tgaggtgatc ggccatgaat aacataatcc ctatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gacgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat tgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aactggatgt ttctactgca tgcagcgata ttcgcctgtg
    13021 tatgtatcag cgccgctttg atgccggccg ccacgcttcc gctttgcgca gtgcatatgc
    13081 tgtgggcggt gatcattgac tttcctgtct ttctgcaggc gcctccgcag cagagcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggtattcagc ggcttctttt
    13261 cgttccagat gatgaacacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttttgct catctgctcg ccgatcgccc ttttgtactc gattgaaaaa aatgaccgga
    13381 tgttgctcat cacgcttccg atcaagcgga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 tatcaggtta actgcggatg aaaaaaggcc ctccttcagc tggcagacgg agcagcagct
    13621 atggagcggt ttctcaaaat atcggtctta tctgttttgt cttcccctat tcttagccac
    13681 attagccggc accgctgtat ccttggcggt cattccgata gccggtctgg tcatagtcta
    13741 ttacctgcaa aaacaggatg gtggtttctt tgatacaagc aaaagagaac ggcttggaag
    13801 ttaacctgct gaagactcat caattttcaa ctatatcaat cgccgcgagc tttctgaaac
    13861 cgatcgaaag cgcggcggaa cctgaggaag aaacaattta tttttacggc gccgccgcgt
    13921 acctgaagga gcaaatcatt gacgctttcg gttgtgctgc cggcagccgt ttcatgtact
    13981 cagcgaatct cttttttgat cagcagctga aaacctgcgg gacccgtttg attcacccat
    14041 tatataacgg gaatcttcat gttgacgccc tgctgaaaac ttttgcagac ttgtctttcc
    14101 cttcttctct ttcattcgaa gcagttgaaa aggccaggaa tgagctgctg ctgagaatcg
    14161 aaaagaaatt cactgatccc ttctcctact cggcggcgcg cttggctgag gaggtcttcg
    14221 gaaacccgat gtacggcaca ggcatgtttg gccggagaga caggataaag gcgattcatc
    14281 ctaaacggtt tctcgacgca acggacttta tcgttgattt agtgtcccag caaaaacagc
    14341 tgaacatatt gggacaagta caagcatgtg atgttcgggg acatgccccg caaacgtccg
    14401 ctgtaacgtc cggaagaata cccgtaaacc ggcatgtttt tgaaacagag acacgcagcg
    14461 ctgcaggtcc ttccgtcttg acactcggat ttgactgcgg agagatgaaa gatgccagcg
    14521 attatatcaa aatacagcta atagacggat tactgggaaa gtacggccat tccgctttat
    14581 tcaagcactt cagagagaag gatctggcag tctatcacgt tatcacccgt tacgatgtca
    14641 tgaacaattt gctgcttgtt tcaatatgta cagatcagct tcatgagaaa gacattcccc
    14701 cgcgcgtttt ggaagctgtc tcagcttttc atacagatga gcgggaacta gaacaggcaa
    14761 agcagttttt acgcaatgaa ttgctgctgc aattcgattc tcccgaaggt ctattggcct
    14821 atatggggat cctgcgccgc ttctcctgca cgaaagaagc cttgctggat ggcatctcag
    14881 cggttacatg ccgtgatgta ttgcaattca tagcgaccat caattatatc ggagctcatg
    14941 tagtaagggg atgaagagat ggaaaagaaa gccttttttc aacagctgga tgaacgaacc
    15001 gatatcagat acacagacag cggactaaaa atattcagat tgaaattccc ccgcgcccac
    15061 ctgcggctgt gcaatgtaaa aatcgatttt ggaagccggg atgtatgtat acgggcagaa
    15121 tccggtgata cactgcttcc gtatggcaca gcgcattttt tagagcatct tcttttctgg
    15181 cataacggcc gcaatctgta cagtgatttt tttgcgcatg gcgcgctttt aaacgcattc
    15241 actacctaca ccgataccaa tttcatgttt acctcattac cggatcggct cagacaaacg
    15301 atccccatcc tgcttgatgc tttatggaac cactcatttg acaagaagat tgtcgctcag
    15361 gaaaaagctg tgattacaag cgaaattcaa acagcacacc ttaaccatca gctctcatat
    15421 cattatcagc tgatcagcat gctttctccc tcctcaccag ctgccgtttt ccccgcaggc
    15481 agaatcgaag atattgaggc gctggacatc aatgatttac aaaaagccta taaggctgcc
    15541 taccaagccc atcggatgac actgtttttg attgggggct cagaaaatac agaaacgctt
    15601 ttgcctcctc acctccagct ggaaaagcgt ccggattatc atgctgaaag aaaaatcatc
    15661 ccggcatgcc ctccagccct ctcacaaaaa atggtgctgg gtgatgagga gcggatggaa
    15721 gatacttgga ccggattaca gatcggcgca cttcccgggc aaaacgatct gttgtcgata
    15781 aagctttatt gggatatcgc ggctcgtatt ctatttcaat tagattcacc gttttttcaa
    15841 gagattcagc aaacgtaccg tctggaaatc gatcgcttgt cagccgagac ttatatatat
    15901 gaggatggcg gtttcttgat ccttcacagt caagggaccc attcttcagc ttatatcgat
    15961 gtggcttcat actatgtcac acagaagaaa gaacaggttg ccgcctggct tcaatacggc
    16021 aaggactctt tgacagacgc gatcatttat gacagcgatt atgtgcgtaa atgcttcgag
    16081 tgggcagccg agtgtgacag gtgcgattgc tcgtttcttg acatgtacca catcattcaa
    16141 gatatggatg cgcaggtttt cttgtctctc attgatgcaa tggcatcttc taacaaagcg
    16201 atcattcacg tttctcagaa agaggcgatc agacaatgaa aaaaagcact gtctttaccc
    16261 ttttattgct gcttataggt atggcggctt attccttcgg ctgggttcag gccgttgccg
    16321 aagccgccgc ccaatatgta cagatgatca acaatgacgc tgtgcggctc gggctgctgg
    16381 cttgtaccgc tgccctcctg atgctgcctg cttttctcta tcttcattat gtcacccaat
    16441 ccgtgaaaaa catgacagca gcttttcaga aactcacaca gtctcatcaa agctgctgtg
    16501 actttcagca acacaacttg tgcagccgat atgcagaaga cgtcaaatcg ctgcgtgaca
    16561 gctataaaaa cgtccgccaa acatacgtga tggctgccgt gttgtgccaa gtcatcatat
    16621 tcggctgcat gttcgaaatc gttaaagccg tccctttccg ccttcacacg ccccctgccc
    16681 tttcaatggg acttgcgatg ctactgattc tgtatttatt gttttgcatg cgaacttatt
    16741 tgcggcagct tttccggcac ggcagcctgt tcagaaaagt gtttgcggga gcgctggccg
    16801 cagccgggat ttggtggatg ctcagtttct ctataagtga actgctgttt ctgattatcc
    16861 tggctgccat tcagcaaatc ggatcattta tttataaacg attctcttat cgcagcaccg
    16921 cttctcttga tctataaaat agctacatcg caatcgcaga cggacccgcg ccaaccggaa
    16981 tcaccgtcac ggctgtataa tcacttgtgc ggtacacggt cacagcattg tcgttgggct
    17041 gtgccgcata aatatactgt ttgtccggcg ttacggcgag gtcaaaggcg ccggggagag
    17101 acacgtttgc aatgatcctc tgtctggccg tattaactac atataagtta ttaatgagaa
    17161 acggttcact atatggctct agaaaataag ctctagtact atcgagagaa aatacaatcg
    17221 tcatcagcgt ttcaaataaa cggctgaagt cccctcccct gcttaatgga gacaaactaa
    17281 tctccgttac acctttcggc cacaactcac cattcaacac gtacgcaaaa tttccagcgt
    17341 aaggagttgc aattaaactg ggaaattcaa atgaatctat gatactttct accaactgcc
    17401 cagtatttac atcatattta tcaaccgacc aactgcttcc attagcggta tagacatact
    17461 gtccattcgg atcaagagca aagtctaaag cgccgggtat cggaatgaca tcaatgaccg
    17521 attgagaggc cgtgttaatc acatatatag atccggcggc catcacgtat gcgaactcat
    17581 ctgttggatc aaattcgatt tttctcggcc ctcctccaac agtaatggta tttatgatag
    17641 ttaatgtttt attatcaatc actgagacaa ggttggtatt tccatggagg atatacgtga
    17701 atgctttatc gaaagtaacg cctagattag ttggcacagc agaaaacggg attgttttta
    17761 caacagtgtt taaatctgca tcaatgaccg aaaccgtgct gtctccagta ttggcagtaa
    17821 acacatatga ttgagggtct ggcgatggcg gtaaaacaag tgtcccggcc accgtaagcg
    17881 gactgccgta gaaaggcggt acaatgagaa gatcttccac tgtcatttga ctaaaatcag
    17941 gacagcggtc agactgtgct gcataataaa caacttgatc aatctcttcg gtatgaatca
    18001 ccgaaacagc cccgtctcct tgtccatatt gatttcgtac aggcgacaca ctgacaagaa
    18061 gcgtaatggt cccttgtact ctcacagcat atcgaacacc gatatcttct ggttccggcc
    18121 cagtctggat taagcaaggc tcactgatac aggacaaatt gtctgtactc catgtaacag
    18181 ccgctgacgc ttctgccgaa tcaaccttga agccctcagg gatatctatc ggcacttgaa
    18241 acggcgcttc ccggctaatt tcctcatcac aaaaacagaa acaattttcc tgtaaagcag
    18301 aaagatcatt ctttttcatg atttcacgtc cttttagaaa tgcacaacat gcagcggtta
    18361 aatcgtaatg gcacccggtg aaaccccaag agatatcaca gtttccacag aataatcatc
    18421 tgtgttgtaa acaatgatgc tctgctctat aaaacgagtt gcatacagaa aatcgccatt
    18481 cggggtaaac gcatagtctg ttgctgattg cggaagattt ccaattacac ctgctccatt
    18541 cggactgaca gaatataaat tgccagtgaa gctgtcatgt aaatacacct ctgatccact
    18601 cgtaaacatt acatatagcc cgtcaggctc cagctcttgg gtatccctga tcgtaaacgt
    18661 atttaaatca ataaccgtca aataattgaa taagaattct tgttctaata catacgcata
    18721 ccgctccgta gaatctgttt ctatggatga tacgataagc tctcgttcaa tcgttcctaa
    18781 gacttcaccg gtagataagt ccactttttg cactaaccca aaattaagaa cataggcgaa
    18841 caacccattg gggtcaattg caatatcaaa accttctaca ggaatagacc tctcaacagt
    18901 caacgtatca attccaatca cataaatggc agtaccggtg aaaacataag caaactcatg
    18961 attagggata aatctaatca atcgaggcgg ctgatccagc aatatagttg ctgtcactgt
    19021 taatgtgtca taatcgatga cagaaatcac attattgttg ggatgtaaga caaacacagc
    19081 gcttttatct ggcgtaattt caatacctgc cggattgtac ggaagagcaa tcgttgtcac
    19141 aacagtatgg gtgtttgtat caatcacaga aactgattga tcatttggat tcgctgtaaa
    19201 cgcgtagacg ggttccggct ccggtacaag cacaatcgtc cccgtcaccg ataaaggact
    19261 gccgtaaaac ggcggaacaa caacaaggtt ctcaatcgtg atgtcactga tatccgggca
    19321 atcatccggt tcatcggaat aatagacgac ttgatcgatt tctgcattgt gaatgacgga
    19381 aacagccccg tccccttgtc catattgatt tcgcacaggt gagacactga cgagtagcgt
    19441 aacggttccc tgcaggcgca ctgcaaattg aacaccgacc tcatcaggct ctggccccgt
    19501 ttgaattaag caacggtcac tgacacaaga aaggctgtct gcattccacg tcacgtttgc
    19561 aacagcttca gccggatcaa cgacaaatcc ttcaggtaat tcaatcggcg cttgaaacat
    19621 ggcttctcgg cttgcttctc cctcacaaaa acataagcac tcttcttgtt ctgctcctgc
    19681 tttttcttta aaggaaagct tattttttct cattccttca cttccttttc agacatacac
    19741 tgctcacgca gatataacag aatatggaag agtaacgtgt ttgcttgtac aaattactga
    19801 gggtaaacgc ttctttttga aaatatatct ccaaacatgc ggtgtaacga aagaaaaaat
    19861 tgcggttttt ttgcgcttct cacaagaatg ttgatgataa aatatgacat atatagaatt
    19921 atgaagggag ggatttgcaa acgtgacagg tgtcatatct tcttcttcca tcggagaaaa
    19981 gattaacgaa tggtatatgt acatacgccg attcagcata cccgatgcag aatatttgcg
    20041 acgagaaatc aagcaagagc tggatcaaat ggaagaagat caagaccttc atttgtacta
    20101 ttcactgatg gagtttcggc acaacctaat gcttgagtac cttgaaccgt tagaaaaaat
    20161 gaggattgag gaacagccga gactgtctga tctgctgctt gagattgata aaaaacaggc
    20221 tcgtttaact ggtctgcttg agtactattt taatttcttc agaggcatgt acgagctgga
    20281 ccagcgggaa tatctgtcgg ctattaaatt tttcaaaaag gccgaaagca agctgatatt
    20341 cgttaaggat cggatagaga aagctgagtt tttctttaag atgtctgaat cttattacta
    20401 tatgaaacaa acgtattttt caatggacta tgcacggcaa gcatatgaaa tatacaaaga
    20461 acatgaagct tataatataa gattgctgca gtgtcattct ttatttgcca ccaatttttt
    20521 agatttaaaa cagtatgagg atgccatctc acattttcaa aaagcttatt ctatggcaga
    20581 agctgaaaag cagccccaat taatgggaag aactttgtac aatatcgggc tttgtaaaaa
    20641 cagccaaagc caatatgagg atgccataac ttatttcaaa agagcaatag ctgtttttga
    20701 agaatcaaat attcttcctt ccttacctca agcgtatttt ttaattacac agatccatta
    20761 taaattagga aaaatggata aagctcatga atatcatagt aagggaatgg cttattcaca
    20821 aaaggccgga gatgtaatat atttatcaga gtttgaattt ttgaaatctt tatacttatc
    20881 aggcccggat gaagaagcaa ttcaaggatt ttttaatttt ctcgaaagta aaatgttgta
    20941 tgctgatctt gaagatttcg ctattgatgt ggcaaaatat tatcatgaac gtaaaaattt
    21001 tcaaaaagct tctgcttatt ttttgaaggt ggaacaagta aggcaactta ttcaaggagg
    21061 agtgagtttg tatgaaattg aagtctaaac tattactctc ttgtctggct ctaagcactg
    21121 tgttcgtggc aacaactatt gcaaatgcac ctacacacca aattgaagtt gcacaacgag
    21181 gaatgattta accgccgtcc atcggcggtt ttttgtccct ctttacccag tctcccaatc
    21241 cattctatga ttttttcaat aatcttaaaa atagtggaaa tgcagcatgt ctctaaaaag
    21301 tgtgagaacc cactttactc aatggaatcg agaaaatgat gtgacggagt tcgaaacgtc
    21361 gagtgcgaca gttgaacagg cagctgagac aatcggcgta agcctgtcta gaatcgccaa
    21421 gtccctgtcc ttcagagggg aaggagatca ggtgattctg attgtggcag ccggcgatgc
    21481 caagatcgac aacaaaaagt ccaggcaaac atttggcttt aaagcaagaa tgctctctcc
    21541 taatgaggta ctggagcaga caggccatga aattggagga gtttgcccaa ttggatagac
    21601 tcatgatcct ga
//
