LOCUS       NZ_CP073265            21610 bp    DNA     circular CON 21-MAY-2024
DEFINITION  Bacillus atrophaeus strain CNY01 chromosome, complete genome.
ACCESSION   NZ_CP073265
VERSION     NZ_CP073265.1
KEYWORDS    RefSeq.
SOURCE      Bacillus atrophaeus
  ORGANISM  Bacillus atrophaeus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4144521)
  AUTHORS   Wang,X., Ding,Y., Du,B., Liu,K. and Wang,C.
  TITLE     Genome of Bacillus atrophaeus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4144521)
  AUTHORS   Wang,X., Ding,Y., Du,B., Liu,K. and Wang,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2021) Shandong Agricultural University, College of
            Life Sciences, 61 Daizong Street, Taian, Shandong 271600, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v4; CANU v. 1.71
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 368.0x
            Sequencing Technology             :: Illumina NovaSeq; PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018140555.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 02:43:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,208
            CDSs (total)                      :: 4,097
            Genes (coding)                    :: 3,947
            CDSs (with protein)               :: 3,947
            Genes (RNA)                       :: 111
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 81 of 150
            Pseudo Genes (incomplete)         :: 105 of 150
            Pseudo Genes (internal stop)      :: 31 of 150
            Pseudo Genes (multiple problems)  :: 58 of 150
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:49:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3763592
            Orig. end                         :: 3785202
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP073265.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21610
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="11"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21610
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21610
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11610](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11610
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(148..162)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(240..3926)
                     /locus_tag="KCX77_RS18865"
                     /old_locus_tag="KCX77_18865"
     CDS             complement(240..3926)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="KCX77_RS18865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18865"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_063638153.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTYEDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLITMWREALQTHKNPLEAWKSIVEHPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFFVTLSKEDGAYTAGRFLHAKDIGRQTEHDQWKPAVWNERTNAFAIPQGTMGSRWDG
                     QKKWNLHMADEDTGEQIEPRLSVLGIEDEIGTVRIPYFSDEGNRVLERDLPIKKLNLNN
                     EDVYVTTVFDLILANYGVNRGIGQKSAASFDDAEPFTPAWQEQVTGIKREMVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGAPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNKNGIDLYKEAETAGARTTKDVADYVARQLQEKKLKFAIEDP
                     DDEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSESIRPEEIKWHDQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAISDLAEEVEMEPVKEAVATPLLHDTMQEMAQPFGKINDWSKGECEAV
                     PGKTMPNIHVVERDYKQIFHKMTALGPNTALKPSGTKGMSWSIADEYESLKKRLGEITT
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLEDITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIRDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3992..4007)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    4020..4035
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.28"
                     /tool="antismash"
     gene            complement(4066..4542)
                     /locus_tag="KCX77_RS18870"
                     /old_locus_tag="KCX77_18870"
     CDS             complement(4066..4542)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014115540.1"
                     /locus_tag="KCX77_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18870"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_212063940.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKHLPMFNQVSLPIVETLLNNGKFISCSSDQSPSFL
                     HSQSVYIVLKGSIHFIDSRLPEGSRAIAFWKKGDVFPIDQNGELLLSPFISVKTSHDTL
                     VLEIPFCKFKKIMTYHPQLQTNFLVMLQENLFFSYQLFLRYLHTSQDENVTPDS"
     misc_feature    complement(4600..4615)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4685..5405
                     /locus_tag="KCX77_RS18875"
                     /old_locus_tag="KCX77_18875"
                     /pseudo=""
     CDS             4685..5405
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="KCX77_RS18875"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18875"
                     /product="YwiC-like family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKVLIPKQHGAWAMLLIPFCLGMVKGGPVLWHIPLFTGWLFLYLT
                     VYPITLAVKKKKTKDYQKWIFYYGIAACCSIIAVVIHKPAFIWLGFSLFPLFLVHVYYA
                     RRKNERALLNDIAGVLFFSTGGLASCWLGAGSLDGWAWFIFAQSSLFFYRKFLLCEVYD
                     PGEKQQNICILFMGISPASSLSFYISRSKLGGSRFYSKQFESMVLTRKGAIY"
     gene            complement(5445..6161)
                     /locus_tag="KCX77_RS18880"
                     /old_locus_tag="KCX77_18880"
     CDS             complement(5445..6161)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="KCX77_RS18880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18880"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_003326506.1"
                     /transl_table=11
                     /translation="MNFLSVRKSDKDLLSQDLHQLLESISTKRKIEKNTFLFQEGMDAK
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKNDIVGELTLFTEEPRYMLSAKVLADGEVFV
                     INKNKLEKELVQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VKRSDGILINIALTNHDLAKFCAAARESVNRMLGDLRKQGIISIEESGKIVLHQRDYLR
                     CEIECENCPLDICNID"
     gene            complement(6273..7460)
                     /locus_tag="KCX77_RS18885"
                     /old_locus_tag="KCX77_18885"
     CDS             complement(6273..7460)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="KCX77_RS18885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18885"
                     /product="nitrate/nitrite transporter"
                     /protein_id="WP_003326505.1"
                     /transl_table=11
                     /translation="MINRQNIQLSLQSCSLVAGFMVWVLISSLISQMSSDINLSAGDIS
                     LVTAIPVILGSLLRIPLGYYTNRFGARMTFMISFLLLLFPVFWISIADSVFDLAVGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGFINGIYGAGNIGTAITTFAAPVVAQSVGWKSTVQ
                     MYMVLLALFALLHFFLGDRNEKKVKVSVKVQIKAVYRNHLLWFLSLFYFITFGAFVAFT
                     IYLPNFLVQHFGLSPVDAGFRTAGFIAVSTLLRPVGGFLADKVSPLRMLMYVFAGLTLS
                     GIILSFSPSLGIYAFGALTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEAALASFVIVIWMYWQERMKTHTERNGHSVN"
     misc_feature    complement(7525..7540)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    7537..7552
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.89"
                     /tool="antismash"
     misc_feature    7543..7556
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.25"
                     /tool="antismash"
     misc_feature    7544..7557
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
     misc_feature    7545..7558
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.38"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="KCX77_RS18890"
                     /old_locus_tag="KCX77_18890"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="KCX77_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18890"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_212063941.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLADESQIPNVILETPKDKTHGD
                     YSTNMAMQLARIAKKAPRQIAEDIVASFDKGKASIEKLDIAGPGFINFYMDNQYLTKLI
                     PSVLEAGEAYGETNIGNGERIQVEFVSANPTGDLHLGHARGAAVGDSLCNVLAKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKEMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VKEEESERQKFFREYGLKYELEKLRVDLENFRVPFNVWYSETSLYENGKIDKALEALRK
                     QGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYQKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNDNPVYYAQYAHARICSMLRQGEEQGLTP
                     AADLDFSAVNSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLAASLHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /locus_tag="KCX77_RS18895"
                     /old_locus_tag="KCX77_18895"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="KCX77_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18895"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_212063942.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIADDGKEEVIEFRTSGFYHVKQNKVYLSYYE
                     EHDLGKVKTIVKVSESEVFVMRSGAVKMNQRFVPGVSTIAKYKMSFGELELTTSTKSIQ
                     SDIGKEKGRISIAYDMHVGDEQQHLHNMTITYEGGLDA"
     misc_feature    9868..9882
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.54"
                     /tool="antismash"
     misc_feature    9894..9909
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="KCX77_RS18900"
                     /old_locus_tag="KCX77_18900"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="KCX77_RS18900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18900"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 8.9e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="KCX77_RS18900_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="KCX77_RS18900_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10264..11610
                     /gene="albA"
                     /locus_tag="KCX77_RS18905"
                     /old_locus_tag="KCX77_18905"
     CDS             10264..11610
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="KCX77_RS18905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18905"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_212063943.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1054.7, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.3e-27,
                     bitscore: 92.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.6e-07, bitscore: 27.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 3.5e-08,
                     bitscore: 31.3, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.8e-07, bitscore: 28.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 5.3e-43, bitscore:
                     145.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-21, bitscore: 75.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.3e-10, bitscore:
                     38.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.2e-08, bitscore: 32.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIERMFPFISESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLN
                     KTAYELCMLMDGQKTAEQILEYQCAAYNESPEDHKDWYYEMLDMLLNKQVIRLTDQPEY
                     RRIATSGSSDFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSLEQFKKTADMLYEK
                     GVLTCEITGGEIFVHPNANELLEYVLKKFKKVAVLTNGTLMRKESLEILRAYKQKIIVG
                     ISLDSVHSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDMIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFDSALVHKLWKAQAPRF
                     SEHCKKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10279..10557
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KCX77_RS18905_Subtilosin_rSAM_RRE.1"
                     /evalue="3.60E-29"
                     /identifier="RREFam018.1"
                     /label="KCX77_RS18905"
                     /locus_tag="KCX77_RS18905"
                     /protein_end="98"
                     /protein_start="5"
                     /score="92.0"
                     /tool="antismash"
                     /translation="MFPFISESVRVHQLPEGGVLEIDYMRDNVSISDFEYLDLNKTAYE
                     LCMLMDGQKTAEQILEYQCAAYNESPEDHKDWYYEMLDMLLNKQVIRL"
     gene            11623..11784
                     /locus_tag="KCX77_RS18910"
                     /old_locus_tag="KCX77_18910"
     CDS             11623..11784
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="KCX77_RS18910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18910"
                     /product="bacteriocin biosynthesis protein AlbB"
                     /protein_id="WP_003326500.1"
                     /transl_table=11
                     /translation="MSPTQRKWLLYILSFVFVIGAVVYFVKSDYLFTLISIVIAIIFGM
                     RARKAESR"
     gene            11781..12500
                     /locus_tag="KCX77_RS18915"
                     /old_locus_tag="KCX77_18915"
     CDS             11781..12500
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="KCX77_RS18915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18915"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_212063944.1"
                     /transl_table=11
                     /translation="MSMLDIHALSVWYEQDNVILENVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGSFKLCGIEVNAKTPLKTSDQLKTNRYFAADYPLLFTEITAKEYVS
                     FVHSLYQKEFQEQQYVSLAEEFHFSQYTNRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYEIMQEYCKAGGTILFSSHLLDVVKRFCHYAAILHDKQIRKLIPI
                     KDDTDLRREFFEVIGHE"
     gene            12493..13821
                     /locus_tag="KCX77_RS18920"
                     /old_locus_tag="KCX77_18920"
     CDS             12493..13821
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326498.1"
                     /locus_tag="KCX77_RS18920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18920"
                     /product="bacteriocin biosynthesis protein AlbD"
                     /protein_id="WP_106047188.1"
                     /transl_table=11
                     /translation="MNNVFQILSLLFKQLYGRQGKKDAIRITAGLAVLALFEIGLIRQA
                     GIDESVLGKTYVTLALLFMNVYMVFISVSSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGTGTLSGTETLFWIGKFSFFTVYSILLGVLLSNLFVKKKG
                     FVFLLHAAAFACICASVVFMPAVTIPLCGVHMAWGVFFDFPSFLQVPHQQNKMHSFMRT
                     SEFSFYKREWNRFISSKAMLLNYIVMAAFSGFFSFQMMKTGIADQHIIYIVITALLLIC
                     SPIALLYSLEKNDRMLLITLPIKRRTMFWAKYRFYSGLLAGGFILIVMIVGLISSQPIS
                     VMTFLQCIELLLMGAFIRLTSDEKRPSFGWQTEQQLWSGFSKYRSYVFCIPLFLATIAG
                     TVISLAIIPIAGLIIVYLLQKQEGGFFDTRRKSERFGNEPVND"
     gene            13769..14956
                     /locus_tag="KCX77_RS18925"
                     /old_locus_tag="KCX77_18925"
     CDS             13769..14956
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003222011.1"
                     /locus_tag="KCX77_RS18925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18925"
                     /product="insulinase family protein"
                     /protein_id="WP_283246494.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 4.5e-06,
                     bitscore: 24.7, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQGEKVNDLEMNLLTTDQFSTISIAASFLKPMEIAAEPEEETMY
                     FYGAAAYLKQNITDVFGYAAGSRFIYSANLFFDRQLKTYGTRLIHPLYHKNLNIDDVLE
                     TFVDKSSLPASLPADIAETAKADLLLKIEKKFADPFSYSAARLAEETFGSPMYGTAMFG
                     RKEKVQAIQPKRFLDASDFKTDLLSQQKQLYVIGNVQELHAGGYSRHAPSMNVRKPVNK
                     NIYETETRSAAGPSVMTLGFDCGEMNGFRDYIKIQLIDGLLGKYGHSALFRHFREKQMA
                     VYHVITRYDIMNNLLLVSVCTDRVQEKEIPPRVIETVMNFHVDDQELEKAKQFLKNEIL
                     LQLDSPEGLLAYMGILRHYLYKKEDILDGISTITCRDLLQYVTNIEYIGAHVVRG"
     gene            14962..16239
                     /locus_tag="KCX77_RS18930"
                     /old_locus_tag="KCX77_18930"
     CDS             14962..16239
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014115551.1"
                     /locus_tag="KCX77_RS18930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18930"
                     /product="pitrilysin family protein"
                     /protein_id="WP_212063945.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 9.4e-12, bitscore:
                     43.1, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKETFFHQLDARTEITYADNGLKICRVKFPNAHMRLCNVKVNFG
                     SRDIRLHSGDSEKVLPYGSAHFLEHVLFWHNGRNLYSDFFDHGALLNAFTTYTDTNFMF
                     TSLPDRLEHTIPKLLDALWNPSFDENIVAQEKSVIKSEIETAHLNQQLHYHYQMLNLLS
                     PASPAAIFPAGRTEDIEALTINDLKEAYATGYQPQRMTMFLIGGSEDTETILPSHLRLR
                     GRSGHTAKRKFMPACPPLLQNQSLGDAECSGETWTGLHIGALPDKNDLFTLQMYWNIVS
                     RVLFHIDSPLFQEIRQTRLLNIQSLSAESHVSEDDGFLILHSKGAHSSAYIDVAANYVM
                     QQKCQAEAWLEYGKESLLNAIIYDSDYVRKCFEWAAECERYDCSFFELYRLIQNMTVQD
                     FLYLIDTVASAKKATIHVSHPEVVGQ"
     gene            16236..16937
                     /locus_tag="KCX77_RS18935"
                     /old_locus_tag="KCX77_18935"
     CDS             16236..16937
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015250988.1"
                     /locus_tag="KCX77_RS18935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18935"
                     /product="bacteriocin biosynthesis protein AlbG"
                     /protein_id="WP_212063946.1"
                     /transl_table=11
                     /translation="MKKSTVFTVLLLLMVMAAYSFGWFQASAEAAGQYVQLIKNDYVRL
                     GLLSCAASVLMLPAFLYLHYVTRSVKSMTAAFQKITQSHQSCCDFQHRKLCSRYAGDVK
                     SLRESYKGIRQTYVMGAVLCQVIVFGYMFEVVKSTPISFNAPPAVTKGLAIVLIIYLLF
                     YMRSYLLQLLQNGQTAKKAVVLLLAGAGIWWMLSFTMSELLFLIILAVIQQIGSFIYKR
                     VSFRSSASLDL"
     gene            complement(16944..18320)
                     /locus_tag="KCX77_RS18940"
                     /old_locus_tag="KCX77_18940"
     CDS             complement(16944..18320)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012118684.1"
                     /locus_tag="KCX77_RS18940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18940"
                     /product="YncE family protein"
                     /protein_id="WP_212063947.1"
                     /transl_table=11
                     /translation="MKKNDLSAFQENCFCFCDEEISREALFQVPIDIPEGFTIDSAEAA
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVQYAVRLQGTVTLLVSVSPVRNQYGQGDGA
                     VSVIDNAEIDQVVYYSDNPDDCPDFSDITIENLVVVPPFYGSPLSVTGTIVLVPAPDQR
                     SYVFTANTGDSTVSVIDTDVNTLVSTISLSDIPTDLGVTLDKAYTYVLHRNANLVSIIN
                     NETLTVTQTIPLAGAPRKIQFETGGEFAYILAGGSSIYEINISSQTITNTFTVSPAADD
                     FALDPNGQFFYTTNSVFWVVNKYDINTGQLIDSLSNFETPNLIETPLIGDFAYLENGEL
                     RPNVVSVIDLTTFSESSQINRLFDGLITIVFSADGTRAFFLEPYYDSFPENLTVVDTTL
                     HTFITTASLPGASDLTVTPDNQYIYVAQPAANTVTVYRTSDYTAVAVILVGAGPSAISM
                     "
     gene            complement(18360..19721)
                     /locus_tag="KCX77_RS18945"
                     /old_locus_tag="KCX77_18945"
     CDS             complement(18360..19721)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="KCX77_RS18945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18945"
                     /product="YncE family protein"
                     /protein_id="WP_212063948.1"
                     /transl_table=11
                     /translation="MKKIERSFKEKAVRQQEDCLCFCEEEASREAMFQAPIEVPEGFVV
                     DPAEAVANVTWNADSLSCVSERCFIQTGPGPDEIEIHFAVRLQGTVTLLVSVSPVRNQY
                     GQGEGAVSVIHNVEIDQVVYYSDEPDDCPDLSDITIENLVVVPPFYGSPLSVTGTIVLA
                     PEPEPEPVYAFTANPDDQSVSVIDTNTHTVITTISLPYEPTGIEITPDKASTFVLHLNN
                     SVISVIDNGTLTVTASIPLDQPPETIKFMPEHDFAYVLAGNAIYVIRIETSAVERSIPV
                     EGYDIAIDPNGMFAYVLDFGLVQKVDLSTGEVTGTIERELIVNSIETKPPERYAYVLEE
                     DHFFNYLTIIDLDTFTISSTQELEYEGEYLMFKSGSGVYLFDGFTHNLYSVSPSGAGII
                     GNLPQSARDFAFTPNGEFLYATHFIEQSITVYNTDDYSVETVISLGVSPSDIAI"
     misc_feature    19818..19827
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            20004..20558
                     /locus_tag="KCX77_RS18950"
                     /old_locus_tag="KCX77_18950"
     CDS             20004..20558
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010333191.1"
                     /locus_tag="KCX77_RS18950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KCX77_18950"
                     /product="YdhK family protein"
                     /protein_id="WP_212063949.1"
                     /transl_table=11
                     /translation="MKRNTTLIGIVSLLLLLMLSACGSDTQDKKSDQTMNMDDTHTHSE
                     SSEIPEGLTAAQHPTYKVGSQAIIKADHMKGMKGAEATITGAYDTTAYAVSYTPTTGGT
                     RVENHKWVIQEEIKNASDETLKPGTDVIIEADHMKGMKGATGKIDSAEKTTVYTVDYTP
                     TTGGEKVKNHKWVTESELSSK"
     misc_feature    20722..20738
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     misc_feature    21133..21146
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.67"
                     /tool="antismash"
     misc_feature    complement(21154..21167)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.42"
                     /tool="antismash"
     misc_feature    21450..21462
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
ORIGIN
        1 gacggttggt tttcggtcct gatttcagct caagctttcc tttttttaat gtccagccgc
       61 ctttatattt atcttggtcc tcccactgct tcggatagcc gatgccaggt tttgtttcaa
      121 cattattgaa atacatatat tcggcaccgg aacggtttgt ccatgtgttt ttgcaggtca
      181 cgctgcacgt gtggcagccg atgcatttat ctaagttcat gaccattccg atttgcgctt
      241 taatcttcaa gccaatcgac ctccttcagc ttgcggatga ccacattcag atcgcgctga
      301 ttccccgtag ggccatagta gttaaagccg tagctgagct gggcatagcc gccgatcatt
      361 tgtgtcggtt taacatgaat ccttgtcgga ctgttatggg tgccgccgcg gttattcgtc
      421 agttttgtgc cgggtacgtt gatgtggcgg tcttgtgcat ggtgcataaa cgccatccct
      481 ttaggaatac ggtgagaaag aacggctctc gctacgacaa cgccatttcg gttgaagcat
      541 tcaatccaat cgttgtctcg gatatctgtg tcctctgcat catctttatt catccacact
      601 gtcggccctc cgcggaatag cgtcagcatc ggtaatgaat caaagtacat gctgtggacg
      661 gaccatttgt tatgcggcgt taaataattg agaacgattt ctttgccctc ttgatcaggc
      721 cgtttactca gaaacggacg atgctggagg atcggtttaa atgtcgccat cgtttccccg
      781 aactccatca tcagctcatg atcgacatag taagactgtc tgcccgtcag cgtccgccaa
      841 gggattaatt tttccacatt tgtcgtaaac ggcgagtacc tgcgtccccc tttttctgag
      901 cctgtaaatg ccggagacgt gatgaccgtt tttggctgag cggtgatttg ttcgaacgta
      961 aagcattctt cttcccgctc ttcagccagg tcttttaact tcaggtttgt gatgtcttca
     1021 agtgattccc atgctttcac cgcaactttt ccattcgaag tggaagaaag ggttaaaatg
     1081 gcttctgccg cctgcttcgc ctcacttata ttcggacatc ccttggcgac gctgtccgtt
     1141 gtgatttctc ccagtctctt tttgagtgat tcatattcat cggctatcga ccagctcatc
     1201 ccttttgttc cgctcggttt tagggcggtg ttagggccga gtgcggtcat tttatgaaag
     1261 atttgtttat agtcccgttc aacaacatga atgttcggca tcgttttccc cggaacggct
     1321 tcgcattcgc ctttgctcca gtcattgatt tttccgaaag gctgcgccat ttcctgcata
     1381 gtgtcatgga ggagcggcgt cgcgacagct tctttaaccg gctccatctc tacttcttca
     1441 gccaagtcgg atatggcttt tgataatgct ttaaaaatat cccagtctga cttggattcc
     1501 caaggcgctg agatggccgg agcaaaagga tgaataaacg gatgcatatc tgtactgctg
     1561 agatcatgtt tttcatacca agtcgccgcc ggaagcacga tatcggaata caatgccgtt
     1621 ccagccattc gaaaatcgag attgattaat aagtcgagct ttccttccgg tgcttgatca
     1681 tgccatttga tttcttccgg acggatgctc tcgctgtcgt cattcatcaa tccgtttgtc
     1741 gtccccaaga gatgcttaag aaaatattca tgcccttttc ccgaacttga gatcagattc
     1801 gctctccata caaaaagatt tctcgggaaa ttggcttcat cgtcaggatc ttcaatggca
     1861 aatttcagtt ttttctcttg gagctggcgg gccacatagt cagcaacgtc ttttgttgtc
     1921 cttgcccccg ctgtttcagc ttccttgtaa agatcaatcc cgtttttatt aaacgtcggg
     1981 taagacggga gccaccctaa tcttgccgcc agtacattgt agtcggcgtg atgcttgtag
     2041 cgggaggatg ctgcgatcgg agaagccaag tcactgatcg gctgatcctc gtagcgccac
     2101 tggtctgtcg caaagtagaa gaatgatgtg ccgttttgca gctttggcgc cccctcccag
     2161 tcctttgcat tagcaatcgt ctgccagcct tcagccgggc gaagcttttc ctgccccaca
     2221 tagtgagccc atccgccccc gtttacacct tgggcgccga ctaataaaac aagatttaaa
     2281 accgcccggt aaatcgtgtc agagttgaac caatggttaa ttcccgcccc tacgataatc
     2341 attgaccgtc cgtctgtatc gatcgcattt tgggcaaatt ctctggcaat tttaacgacc
     2401 atctcccttt tgatccctgt cacctgttct tgccaggcgg gtgtaaacgg ctcagcatca
     2461 tcaaacgagg cggctgattt ctgcccgatt ccccgattga cgccatagtt tgccagaatt
     2521 aaatcaaaaa cggttgtgac atatacgtct tcattattca ggtttagttt cttaatggga
     2581 agatcgcgct caagcactct gtttccctca tctgagaaat aagggattcg aactgtgccg
     2641 atttcgtctt ctattccgag cactgacagc ctcggttcaa tttgttctcc tgtatcttca
     2701 tctgccatgt gcagattcca tttcttttgg ccgtcccatc gtgatcccat tgttccttgc
     2761 ggtatcgcaa atgcgtttgt acgttcattc cacacagcag gcttccactg atcatgctct
     2821 gtttgccgtc cgatgtcctt cgcatggaga aaacgtccgg ctgtataagc gccatcttct
     2881 tttgacaagg tgacaaagaa cgggaaatcc gtgtattgct ttgcgtactc tatgaaacgc
     2941 tctgtttctt gattcacgta aaattcttgc aggatgacat gccccattgc catcgcaagc
     3001 gcgccgtctg ttccctgacg gatgctcagc cagtcatccg caaattttga cgattccgca
     3061 aaatccggac taattgagat gacttttgcc cctttatagc gggcttctgc caaaaagtgc
     3121 gcatccggcg ttcttgttaa cggtacattg gatccccatg tgatgatata gcccgaattg
     3181 taccagtcac tgctttccgg cacgtctgtc tggtctcccc agatttgcgg agacgctggg
     3241 ggaagatccg cataccaatc ataaaagctc agcatagggc cgccgattaa tgacataaac
     3301 cgcgagcctg acgcgtggct gatcattgac atggcgggaa tcggagaaaa tccgacgttg
     3361 cggtcagggc cgtatttcat gactgtatat aatagagaag cagaaatcag tttcagcacc
     3421 tccggccact cagcgcgcac aaaaccgcct tttcctctcg cctgtttata ggacttcgct
     3481 ttttccggat gctcaacgat agatttccat gcttccaatg gatttttgtg tgtttgcaat
     3541 gcttcccgcc acatagtaat cagcacaccg cgaacgtatg gatatttgac acgcagcggg
     3601 ctgtagatat accaggaaaa acttgccccg cggggacagc cccttggctc gaagtcaggc
     3661 atatcagggc cagttgaagg ataattcaaa ttttgccctt cccacgtgac gatgccgttt
     3721 ttcacataaa tattccagct gcaagatccc gtgcagttga ctccgtgggt ggagcggaca
     3781 actttatcgt actgccatct gtttctatat acattctccc aatcgcgatc ttcgtatgtt
     3841 gtttgactat gtttattaga atgatgctca ataggagaga aatagtttag tctcctgaac
     3901 agcggactca ttttcttctt tttcatcgtt gcttcactcc tttgagtcag gtgattctca
     3961 tttcactata tacagaggta gcatcgttcc ttgtgaactt tgtcacatac accccttatt
     4021 tcacaaatgt ttcacattca ggattcaaaa aaacccggtt cctggttagg aatcgggagt
     4081 gacgttttca tcctgagatg tgtgcagata acgcaaaaat aactggtagg aaaaaaagag
     4141 attttcctga agcatgacca gaaaattcgt ctgcagctgc ggatgatagg tcattatttt
     4201 tttaaatttg caaaaaggaa tttccaacac gagtgtgtca tgagatgttt tgactgaaat
     4261 gaaaggagat aaaagcagct cgccattttg atcaatgggg aacacatcac cttttttcca
     4321 aaatgcaatg gcgcgcgatc cttcaggcag tctgctgtca ataaaatgaa tgctgccttt
     4381 taatacaata taaactgatt gtgaatgcaa aaaagatgga gactgatcag atgagcaact
     4441 gatgaacttt ccgttattca gcaatgtttc gacaatggga agagatactt gattaaacat
     4501 tggaagatgt ttcagaaata ataaatagtc acactgattc ataggaaagc ctcctgtggt
     4561 aaggatagct ttagtgtatc ttgattgaat caatacagca gtgatgtaat tcacagaaat
     4621 tatgataaat gtcacttatc ggaagaatga ttgcttttat aatgaaacag aaaggagtgt
     4681 ttcaatgaag gtgctcattc cgaagcagca cggtgcatgg gctatgctgt tgatcccgtt
     4741 ttgcctcggt atggtgaagg gaggtcccgt tctatggcat atcccgctat ttacgggctg
     4801 gctatttctc tatttaaccg tttaccccat taccttggcg gtgaaaaaga aaaaaacaaa
     4861 agactatcaa aaatggattt tttattacgg cattgcagct tgctgctcta tcattgccgt
     4921 tgtcatccat aagcctgcgt tcatctggct cggcttttct ttgtttccgc tgttcctcgt
     4981 tcatgtctat tatgcccgcc gcaaaaacga aagagcgctt ctgaatgata ttgcgggagt
     5041 cttgttcttt agtacaggcg gacttgccag ctgctggctg ggggcgggaa gccttgacgg
     5101 ctgggcatgg tttattttcg cgcaatccag cttatttttt tatcggaagt tccttttatg
     5161 tgaagtctat gatccgggag aaaaacaaca aaacatttgc atactgttca tggggatatc
     5221 acctgcttct tccctttctt tctatatctc tcggagcaag ctggggggct ctcgctttta
     5281 ttccaagcag tttgagagca tggttcttac acggaaagga gcgatctatt aagacgatcg
     5341 gcattcttga aatcgtgaac gcgtgcttct ttttcgcagt catgtgtatt tttttaacaa
     5401 gataaaacaa ggactgaagt ttgcagtcct tgtttatttc ttgattaatc gatattgcaa
     5461 atatccagcg ggcaattttc gcactcaatt tcacatctta aatagtcccg ctgatgcaaa
     5521 acaatctttc cggattcctc aattgaaatg attccttgtt tacgaagatc acccagcatg
     5581 cgattgacac tctctcttgc agccgcacaa aacttcgcca aatcatggtt cgtcagtgca
     5641 atgtttataa gaattccgtc gcttcgtttc accccatagc tatttgacaa acgaatgagt
     5701 gtggaataaa gcgccccttt tttgccatga agaagaaggt cacggatttt ggactgaatt
     5761 tttcgcaggt gggtgctcat ccatttcata aattcaaatg tcaaagcacc gttttgaacc
     5821 aattcctttt ccagtttgtt tttattgatg acaaacactt caccgtctgc taacactttt
     5881 gcactcagca tatatctcgg ttcttctgta aaaagtgtta attccccgac aatatcattt
     5941 ttttggcaga tcctaagcgt cagatccttg ccgtcagacg tcagtttgcc aatttcaatg
     6001 agtcctgatt gaatcagata aagctctttt gcatccattc cttcttgaaa cagaaacgtg
     6061 tttttttcaa tttttctttt tgtactgatt gattccagca attgatgcag atcttgtgag
     6121 agaagatcct tatcagattt tcgaacagag agaaaattca tgagctcacc tcgaagatag
     6181 tcacgttgtg tatttctatt gtaacgtgaa tcgatttgca tcattttaaa aaaacttaca
     6241 atctcgtgaa ttccccaaac gccggcttcc cattagttta cgctgtgccc atttctctca
     6301 gtgtgcgttt tcatcctttc ctgccaatac atccaaatga caatgacaaa gctggctaaa
     6361 gcagcttccg agagcgccat aaatccgatt gcatattgtc ctgtcgcttg aaatacgctt
     6421 gccaggatca gcggcggaaa gaatcctccc aatcccccca tggcagaaac aataccgttt
     6481 gcaattcccg cttgttttga gaaataaaaa ggcaccaatt taaaaactgt tccgtttcca
     6541 attcctgagc agacagcaac tgttaacgcc ccaaaagcgt aaatgccgag actcggtgag
     6601 aacgacaaga taatgcccga taatgtcaga cccgcgaaga cgtacattaa cattctaagc
     6661 ggactcacct tatctgccaa aaatccgcca acaggtctga gaagcgtgga cacagcaata
     6721 aaacctgccg ttctaaaccc ggcatccaca ggactaagac caaagtgctg aacaagaaag
     6781 ttaggaagat aaatggtaaa ggcaacgaac gcgccaaatg ttataaaata aaaaaggctt
     6841 aagaaccaca acagatgatt tcggtaaacg gcttttattt gaacctttac ggaaactttg
     6901 actttcttct cgtttcgatc gcccaggaaa aagtgcagca aagcaaataa agccagcagg
     6961 accatataca tttgcaccgt actcttccat cccacagatt gagcaacaac aggagctgca
     7021 aacgttgtga tggcggttcc gatatttcca gctccgtaaa tgccgtttat aaaaccgtgt
     7081 ttttccttag gataatactt cggaagagat gtcaccccaa tggagaaaac cgctcctcca
     7141 atccccaaga aaaaaccgcc cacggctaaa tcaaacacag aatctgcgat actgatccaa
     7201 aatacaggaa acaaaagcaa tagaaagctg atcataaaag tcatccgcgc gccaaacctg
     7261 ttcgtgtaat atcccaaagg aatgcggaga agcgatccca gaatgacagg tatggccgta
     7321 accagcgaaa tgtcgccggc gctcaaatta atatcagatg acatttgaga aattaatgaa
     7381 gaaatcaaaa cccaaaccat aaatcctgcc accaagctgc atgactgtaa cgataattga
     7441 atgttttgac ggttaatcat tcggcttgcc cctttcaatg attcaataat cagtcttatc
     7501 atacaaaaac tcggtgaata ggattgtgaa gtacatcaca cgttttttta acaaaaaagg
     7561 acaaagcccg gggctttgtc cttttatctt cattacattt tttcaggagc cgaaacgcca
     7621 atcaactgaa gcgcattatt cagcgtgatt tgcgttgctt tcattaaagc taagcgtgcg
     7681 cggcttttct cttcattttc aggatcgatt accttttccg cattatagaa gctgtgcaga
     7741 gaagctgcca agtcataaat atagttcgtc acgcggtgcg gaatgcgttt ttccgccgct
     7801 tccgccactg cttcagggaa gccgccgatc gttttcagca aatcgtattc tttttcagaa
     7861 ttgacggcgc taaagtcaag atcagccgca ggcgttaatc cctgctcttc tccttggcga
     7921 agcatgctgc agattctcgc gtgagcgtat tgcgcgtaat acaccggatt gtcatttgaa
     7981 gtggacaccg caagatccaa gtcaaaatcc atatgtgtat cggcactgcg catcgcgaag
     8041 aaataacgga cggcgtctaa gccgacttct tcaatcaagt cgcgcattgt taccgctttt
     8101 cctgtacgct tgctcatttt cattttctcg ccgtttttat atagatggac gagctgaatg
     8161 atttctactt ctaacgttcc tttttgatag ccaagcgcct caatggccgc tttcatccgc
     8221 ggaatatagc cgtggtgatc tgcgccccag acgttgatca gcttatcgaa tccgcggtct
     8281 agcttgtcct tatggtaagc gatatcaggc agcaaataag tgtaagtgcc gtctttttta
     8341 atcaaaacac ggtctttgtc atcgccgaat gttgttgagc ggaaccaagt tgcgccgtct
     8401 tcttcataca cgtggccttg tttgcgcagc gcttcgagcg ccttgtcgat ttttccgttt
     8461 tcgtataatg acgtttcaga ataccagaca ttaaacggca cgcggaaatt ttctaagtct
     8521 acacgaagct tttccaactc atacttcaag ccgtattcgc ggaagaactt ctgtctttcg
     8581 ctctcttctt ctttgacaaa gcggtctccg tattcttcag cgagacgctt cccgattgcg
     8641 ataatatcct cgccgcggta tccgtcctca ggcatttctt tttcaaggcc gagcgcttca
     8701 aagtaacgga cttcgacaga aagcgccaag ttgttgatct gatttcccgc gtcattgata
     8761 taatattcgc ggctcacatc atatccggct ttagccagca cattgcacag agaatcgccg
     8821 acggctgctc cgcgcgcatg gcctaaatga agatcgcccg tcggattcgc agatacgaat
     8881 tccacttgga tgcgctcgcc gtttccgata tttgtttccc cgtatgcttc tcccgcttcc
     8941 aatacagatg ggatcagctt cgttaaatat tgattatcca tatagaaatt gataaatcca
     9001 gggcctgcaa tatcaagctt ttcaattgaa gcctttcctt tatcaaaaga agctacaata
     9061 tcctcagcga tttggcgcgg ggcttttttt gcgattcttg ccagctgcat cgccatgttg
     9121 gttgaataat caccatgtgt tttatctttc ggtgtctcta aaatgacatt tggaatctgg
     9181 ctttcatcag ccaatcccgc tttcagaacg gctgctttaa tttcctcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtcaa gtcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctg ctgttcgtct cccacatgca tatcataagc tatgctgata cggccttttt
     9361 ctttgccgat gtcagactga atcgattttg tgcttgtagt cagctcaagc tcgccaaatg
     9421 acattttata tttggcaatg gtagagactc ccggcacaaa ccgctgattc attttcactg
     9481 cgcctgacct catgacaaac acttcgctct cgcttacttt cacaatcgtt ttcactttgc
     9541 ccaaatcgtg ttcttcataa taagaaagat acactttatt ttgtttcaca tgataaaatc
     9601 cggaggtgcg gaactcaatg acctcttctt tcccgtcatc cgcaatcaca gattttacat
     9661 ggagcgttat cggtgtctct tgtttcatgc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc gctatttaaa gttcaactgc ttctatctta ccatcattgc
     9781 tcatcagttt tgaagataaa cctcataaaa agcggttaat gaaacgaaga gcatttaaat
     9841 agaaattaat gccgttttga atgttacatt tttctgaaat ctatctaata tttttcacat
     9901 tttcttcaaa atatacatat tgaaaaggta ttttgatagt tttaagatta aattacatca
     9961 gagatatgct agaaaaatta aacaagggag gatttctatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgttcaat cggagctgct tgtttagtgg acggacctat
    10081 tccagacttt gaaatcgcag gtgcaacagg gctattcggt ttatggggat aaagcatttc
    10141 ctaaaagagg catagtaaat tactgtgcct ctttttgaaa agtattttta ctttctatct
    10201 actccttagt tatacataca tgttttctca ttatttgtat catatgtata ggagatggta
    10261 tttttgctta tagagcggat gtttccattt atcagtgaaa gtgtaagagt tcaccagctt
    10321 cctgagggcg gagtattaga aattgattat atgcgtgata atgtctcgat ctctgatttt
    10381 gaatacttgg acctcaataa aacggcttac gagctttgta tgctgatgga cgggcaaaaa
    10441 acggcagaac aaatattaga ataccaatgc gcggcgtaca atgaatctcc cgaagaccac
    10501 aaggattggt attatgaaat gctcgacatg ctgctgaaca agcaggtcat tcgtcttaca
    10561 gaccagcccg aatatcggcg cattgccaca agcgggagca gcgactttcc gatgccgctg
    10621 catgcgacct ttgagctgac tcaccgctgt aatttaaaat gcgcccactg ttatttagaa
    10681 agctcgcctg aagcgctggg aacggtatct cttgaacaat tcaagaaaac agcggatatg
    10741 ctgtacgaaa aaggcgtttt aacatgtgaa ataacgggcg gagagatttt tgtccacccg
    10801 aacgccaatg aactccttga gtatgtatta aagaaattta aaaaggttgc cgtcttaaca
    10861 aacgggacgc tgatgcgaaa agaaagcctg gagattttaa gagcatacaa gcaaaagatc
    10921 atcgtcggta tttcactgga cagtgtccat tctgaagtcc acgattcctt tagagggaga
    10981 aaaggctctt ttgcccaaac ctgtaaaacg ataaaattat tgagtgatca cggtattttt
    11041 gtcagagtcg ccatgtcggt tttcgagaaa aacatgtggg aaattcatga catggcccaa
    11101 aaggtgcgcg atcttggtgc caaagcgttc tcttacaact gggttgatga tttcggaagg
    11161 ggcagagata ttgtccatcc gacaaaagat gccgaacagc accgcaaatt tatggagtac
    11221 gagcaaaatg tcattgatga atttaaggat atgattccga ttatccctta tgagagaaaa
    11281 cgtgcggcga attgcggcgc aggctggaag tcaatcgtga tcagcccgtt cggagaagta
    11341 cgcccgtgcg cgctcttccc gaaggaattt tcattgggaa atatctttca tgattcatat
    11401 gaaagcatct ttgattccgc tctcgtccat aaactatgga aagcgcaggc gccgcggttc
    11461 agtgagcatt gcaagaaaga caaatgccca ttcagcggct attgcggagg ctgttactta
    11521 aaaggcttaa actctaacaa atatcaccgt aaaaatatct gttcctgggc gaaaaatgaa
    11581 caattagaag atgtggtcca gcttatttag gagggaaatg ttttgtcacc aacacaaaga
    11641 aaatggctat tgtatatcct ttcattcgtg tttgtcatcg gcgcggttgt ctatttcgtc
    11701 aaaagcgatt atttgtttac tctgatctcc attgtgattg ccattatatt cggaatgaga
    11761 gcgcggaagg ctgaatctcg atgagcatgt tggatataca cgctttatct gtttggtacg
    11821 aacaagataa cgtcatctta gaaaacgttg atttacattt agaaaaaggc gccgtttacg
    11881 gactgcttgg agtaaatggc gccggcaaaa caacgctgat caatacgctg acaggcgtta
    11941 atcggaattt tagcggaagc ttcaagctgt gcggcattga agttaacgcc aaaacgccgc
    12001 tgaagacatc agatcagctg aaaaccaacc gctacttcgc ggcggattat ccattgcttt
    12061 ttacagagat cacggcgaag gaatacgttt ctttcgtcca ttctctttat caaaaagaat
    12121 ttcaggaaca acaatatgtc agtttagcag aggagtttca cttttctcag tacacgaatc
    12181 ggagaatctc agagctgtct ctcggcaaca ggcaaaaggt tgttctgatg acagggttat
    12241 tgctgcgggc tcccctgttt attttagatg agccgcttgt cggcttggac gtggaatcga
    12301 ttgaagtctt ttatgagata atgcaggagt attgcaaggc aggtggaacc attttgtttt
    12361 cttcccatct gcttgatgtg gtgaaaaggt tttgccatta tgcagctatt cttcatgata
    12421 aacagattcg caaattgatt cctattaagg atgacacaga tctgcgccgg gaattttttg
    12481 aggtgatcgg ccatgaataa tgtgtttcaa attctttccc tgctgttcaa acagctttac
    12541 ggccggcaag ggaaaaagga tgccattcgc atcaccgccg gacttgctgt tctggctttg
    12601 tttgaaatcg gactgatccg gcaggccggc attgatgagt cggttttagg aaaaacatat
    12661 gtcacactcg cgcttctttt tatgaatgtg tatatggtat ttatttccgt ttcttcacaa
    12721 tggaaggaat cctacatgaa gctgagctgt cttttgccaa tctcttcacg tagcttctgg
    12781 cttgctcaaa gcgtggtttt gtttgtggat acttgtttga gaagaacgtt attcttcttt
    12841 attttaccgt tgtttttatt tggaaccggc acgctttcag ggacggaaac gttattttgg
    12901 atcggcaaat tttcgttttt cacagtctac tccattttat taggcgttct attaagcaac
    12961 ctttttgtca aaaagaaggg atttgtgttc ctgctgcatg cggcggcatt tgcctgtatc
    13021 tgcgccagcg tggtttttat gcccgctgtg acgatcccat tatgcggggt tcacatggca
    13081 tggggcgttt tctttgattt cccctccttt ctgcaggtgc ctcatcagca gaacaagatg
    13141 cattcattca tgcggacatc ggaattttcc ttttataaga gagaatggaa tcggtttatt
    13201 tcgtcaaagg cgatgttatt aaactacatt gtcatggcgg ctttcagcgg ttttttttcg
    13261 tttcagatga tgaaaaccgg catcgctgat cagcatatca tttacattgt gattaccgcc
    13321 ttgctattaa tttgttctcc tatcgcttta ttgtattctc ttgaaaaaaa cgaccggatg
    13381 ctgttaatca cgcttccgat taaacggaga acgatgtttt gggcaaaata tcgcttttat
    13441 tccggtttgt tggcaggcgg gtttattttg atcgttatga tcgtcggttt gatcagcagc
    13501 cagccgattt cagtcatgac ttttttgcag tgtatcgaat tgctgctgat gggagccttt
    13561 attcggttaa catctgatga aaaaagaccc tctttcgggt ggcagacgga acagcagctc
    13621 tggagcggct tctcaaaata ccgctcctac gtattttgta ttcccctatt cttagcaact
    13681 atcgctggca ctgttatctc cttggcgatc atcccgattg ccgggctgat cattgtctat
    13741 ttgctgcaaa aacaggaagg tggtttcttt gatacaagga gaaaaagtga acgatttgga
    13801 aatgaacctg ttaacgactg atcaattttc aacaatctcc atcgccgcga gctttctgaa
    13861 accgatggaa atcgcggcag agcctgaaga agaaacaatg tatttttacg gtgcggcggc
    13921 ctatctaaaa caaaacatca ctgacgtctt tggatatgct gccggcagcc gctttatcta
    13981 ctcagcgaat ctattttttg accggcagct caagacatac ggaacccgct tgattcatcc
    14041 gctttatcac aaaaatctca acattgatga tgtgctggaa acatttgttg ataaatcctc
    14101 tcttccggca tctcttccgg ccgatatcgc agaaacggct aaggctgacc ttttactgaa
    14161 gatcgaaaag aagttcgcgg atcctttctc ttactcggca gcccgtctgg cagaggaaac
    14221 gttcggcagt ccgatgtacg gcacagctat gtttggccgg aaagaaaagg tacaagcgat
    14281 acagcctaaa cgctttctgg atgcatcaga ttttaaaact gatttgttgt cccagcaaaa
    14341 acagctttat gtgataggaa acgttcaaga gttacatgcc ggaggatatt ccaggcacgc
    14401 accttccatg aacgttagaa aacccgtcaa taaaaacatt tatgaaacag agacacgcag
    14461 cgccgcaggc ccttccgtga tgacccttgg gtttgattgc ggagaaatga acggtttccg
    14521 tgattatata aaaatccagc tgatagacgg attactcgga aagtacggcc attccgcatt
    14581 atttcggcat tttcgcgaga aacaaatggc ggtttaccat gtcattaccc gctatgacat
    14641 catgaacaat ctgctgcttg tatccgtatg taccgatcgc gttcaagaga aggagattcc
    14701 gccaagagtg atcgaaacgg tcatgaattt tcatgtagat gatcaggaat tagaaaaagc
    14761 gaagcaattc ctgaaaaatg aaatccttct gcaattagat tctccggaag gactcttagc
    14821 ctatatggga attctgcgtc attacttata caaaaaagaa gacattctag acggtatttc
    14881 aacgattacc tgccgcgatt tattacaata cgtgaccaat attgaatata ttggagcaca
    14941 tgtagtaagg ggatgaggag attggagaaa gaaacctttt ttcatcagct tgatgcacgt
    15001 accgagatca cgtacgcaga caatggacta aaaatatgca gagtaaaatt ccccaacgcc
    15061 catatgaggc tgtgtaatgt caaagtcaat ttcggcagcc gggacatccg tttgcactcc
    15121 ggagacagcg aaaaagtgct gccgtacggc tctgcgcact ttttggagca tgttctcttc
    15181 tggcataacg ggcgaaatct atacagcgat ttttttgatc atggagcgct tttgaatgcg
    15241 ttcaccacat atacagatac aaatttcatg tttacctctc ttcccgatcg gctggagcac
    15301 acgatcccga aactgcttga tgctttatgg aatccctcct ttgacgagaa tattgtcgct
    15361 caagaaaaaa gcgtgattaa aagcgaaatt gaaacagctc atctcaatca acagcttcat
    15421 tatcattatc agatgctgaa tttgctttct cccgcatcac ccgctgcgat ttttcccgcg
    15481 ggcagaacgg aggatatcga ggctttaacg atcaatgatc taaaagaagc ctatgcaaca
    15541 ggctaccagc ctcagcgtat gacgatgttt ctgatcggcg gctctgaaga tacagaaacc
    15601 attttgcctt ctcatctccg gctgcgcggc cgctccggcc ataccgccaa gagaaaattc
    15661 atgcctgcat gccctcccct cttacaaaat cagagcctgg gtgatgcgga gtgttcgggg
    15721 gaaacatgga ccggattaca tataggcgca ctccccgata aaaacgatct ttttacattg
    15781 caaatgtatt ggaacatcgt ctcccgcgtt ctttttcata tagattcgcc gttgtttcaa
    15841 gaaatccggc aaacgcgcct ccttaatatc caaagcttat cagcggaaag tcacgtgtca
    15901 gaagatgacg gctttttgat ccttcacagt aaaggggcac attcttcagc ctatatcgat
    15961 gtagcggcaa actatgtgat gcagcagaag tgtcaggcgg aagcttggct ggagtacggc
    16021 aaggaatctt tgctgaacgc gatcatctac gacagtgatt atgtgcgtaa atgctttgaa
    16081 tgggcggctg aatgtgagcg gtatgattgc tcttttttcg agctttaccg gctgattcaa
    16141 aacatgactg tacaggattt tttatatctt attgatacag tggcttctgc taaaaaagca
    16201 accattcatg tctctcatcc agaggtggtt ggacaatgaa aaaaagcact gtcttcactg
    16261 tgttattgct gcttatggtc atggcggcct attcatttgg ctggtttcaa gccagcgctg
    16321 aagccgcggg gcaatatgta cagctgatca aaaatgatta tgtgcggctc ggcttgcttt
    16381 cttgtgccgc ttctgtgctg atgctgccgg catttttgta tcttcactat gtcacccgat
    16441 ccgtcaaaag catgacagca gcttttcaga agataacgca atctcatcaa agctgctgtg
    16501 attttcagca tcgcaagctg tgcagccgtt atgccggcga tgtgaaatca ttgcgcgaaa
    16561 gctacaaggg catccgtcaa acgtacgtga tgggggctgt attatgccaa gtgatcgtgt
    16621 tcggttacat gtttgaagtg gtcaagtcca ctccaatcag cttcaacgcg ccccccgctg
    16681 tcacgaaggg gcttgcgatt gttctcatca tttatttatt gttttatatg aggtcatacc
    16741 tgctccagct tctccagaat gggcaaacgg ctaaaaaggc tgtcgttctg ttattagcag
    16801 gagccgggat atggtggatg ctcagcttta ccatgagtga actgctgttt ctgattatct
    16861 tggctgtcat ccagcagata ggttcattta tttataaacg agtctctttt cgcagctccg
    16921 cttctctcga cctgtgaaaa catctacatc gaaatcgcag acggaccagc gccaaccaga
    16981 atgaccgcta cggctgtata atcacttgtg cgatataccg tcactgtatt ggctgcaggc
    17041 tgtgcaacat agatatattg attgtccggt gttactgtga ggtcagaggc gccggggaga
    17101 gaggcagttg ttataaaggt atgcagcgtt gtatcaacga cagtcaaatt ctccggaaat
    17161 gaatcataat atggctcaag gaaaaatgca cgagtcccgt cagcagaaaa aacaattgtt
    17221 attaaaccgt caaacagtct gttaatttgt gaagattcgc taaatgttgt caaatctatc
    17281 acagaaacga cattcggcct tagctcacca ttttccagat aagcaaaatc ccctattaac
    17341 ggggtttcaa taagatttgg tgtttcaaag ttacttaaac tatcaatcag ctgccctgta
    17401 tttatgtcat atttattaac gacccaaaat acagagttgg tcgtatagaa aaactgtccg
    17461 ttagggtcta gggcaaaatc gtccgcagcg ggtgacaccg tgaatgtatt ggtaatggtt
    17521 tgcgaggaaa tattaatttc ataaatggag ctgccccctg cgagaatata agcaaattcg
    17581 cccccagttt caaactggat ttttcttgga gctcctgcaa gagggatggt ttgtgtaacc
    17641 gttaatgttt cgttgttaat gatcgataca agattcgcat tcctatggag aacatacgta
    17701 tacgctttat ccaaggtaac acccagatca gtcgggatat cagataaaga aatggtactt
    17761 acaagagtat tcacgtcagt atcaatgacc gaaaccgtgc tgtctccagt gtttgcagta
    17821 aacacgtaag atcgctgatc cggcgccggt acaagtacaa tcgtccccgt caccgataaa
    17881 ggactgccgt agaacggcgg aacgacaaca aggttctcga tcgtgatgtc actgaaatcc
    17941 gggcaatcat ccgggttatc agaataatag acgacttgat cgatctctgc attgtcaatg
    18001 acagaaacag ccccgtcccc ttgtccatat tgatttctta caggtgagac actgacaaga
    18061 agcgtaacgg tcccttgcag acgcacagca tattgaacac cgatatcttc tggttccggc
    18121 ccagtctgga ttaagcaagg ctcactgata caggacaaat tgtctgtact ccacgtaaca
    18181 gctgcagctg cttcggcaga atcaatagtg aacccctcag gaatgtcaat cggcacttga
    18241 aacagcgctt ctcggctgat ctcctcatca caaaagcaga aacaattttc ctgaaaagca
    18301 gaaagatcat tttttttcat aatgtcacgt ccttttaaaa atgcacaaca tgcatttggt
    18361 taaatcgcaa tgtcactcgg tgaaacgcca agcgatatga cagtttccac agaataatca
    18421 tccgtgttgt aaacagtgat gctttgctct ataaaatgag ttgcatatag aaattcgcca
    18481 ttcggggtaa acgcaaagtc tcttgccgat tgcggaagat ttcctattat gcctgcacca
    18541 cttggactga cggaatatag attgtgagtg aaaccatcaa acaaatacac ccctgatccg
    18601 ctcttaaaca ttagatattc accctcatac tccagctctt gggtgctact gatcgtaaac
    18661 gtatctaaat caataatcgt caaataattg aagaagtgat cttcttctaa tacataggca
    18721 taccgctccg gcggctttgt ttctatggaa tttacaataa gctcccgttc aatcgttcct
    18781 gtaacttcac cggtagataa gtccactttt tgcactaaac caaaatcaag aacataggcg
    18841 aacattccat tgggatcaat tgcaatatca tacccttcaa caggaataga cctttctacg
    18901 gcagacgttt caattctgat cacataaatg gcattaccag cgagaacata tgcgaaatca
    18961 tgttcaggca taaatttaat tgtttcaggc ggctgatcta gcggaatgga tgcagtaaca
    19021 gtcaatgtgc cattatcgat gacagaaatg acactattgt tcaaatgcaa aacaaacgta
    19081 gaggctttat ctggcgtaat ttctatacct gttggctcgt atgggagaga aatggttgtt
    19141 ataacggtat gagtattcgt atcaattacg gaaaccgact gatcatctgg attcgctgta
    19201 aatgcataaa caggctccgg ctctggttcc ggggcgagca caatcgttcc tgtcaccgat
    19261 aaaggactgc cgtaaaacgg cgggacgaca acaagatttt cgatcgtgat gtcacttaaa
    19321 tccgggcaat catccggttc atcagagtaa tagacgactt gatcgatctc tacattgtga
    19381 atgacagaaa cagctccctc cccttgtcca tattggtttc gcacaggtga gacactgaca
    19441 agaagcgtga cggttccctg caggcggact gcaaaatgga tttcgatctc atcaggcccg
    19501 ggtccagtct gaatgaagca gcgttcactg acacaggata ggctgtctgc gttccacgtg
    19561 acattcgcta ccgcttcagc aggatcaaca acaaaccctt caggcacttc tatcggcgct
    19621 tgaaacatgg cttcacggct ggcttcttcc tcacaaaaac ataaacaatc ctcttgctgt
    19681 ctgacggctt tttctttaaa agaacgctca atcttcttca catgctcact tccttctcag
    19741 aaatagctgc taagcgcagc agtaatagag tatggggaca aaaaggtttt gcttgtacaa
    19801 aagttctaag ccaaaagtgt ttttttaaac tgaaaacggg taaaaagaaa aagagttatt
    19861 tacaaattat gttttatagc aggaatgtca ggttatataa aataaaaaag acttcataag
    19921 gaggatttat ttattcaagc agccttatta cactacttat ataagttccc aagcttctct
    19981 gggtaaataa aaggaggatc acaatgaaaa ggaatacaac cttgatcgga atcgtttctt
    20041 tgctattact attaatgctg tctgcatgcg gcagcgatac tcaagacaaa aaatcagatc
    20101 aaacgatgaa tatggacgac acacatactc attctgagtc cagtgagatt ccggaaggcc
    20161 tgacagcagc acagcaccca acttataaag ttggaagcca agccatcatc aaggcggatc
    20221 acatgaaagg catgaagggt gccgaagcaa ccattacagg agcctatgat acgacggcct
    20281 atgctgtttc ctatacaccg acaaccggcg gaacaagagt ggaaaatcat aaatgggtga
    20341 ttcaagaaga aataaaaaat gccagtgatg aaacattaaa acccggaacg gacgtgatta
    20401 tagaagcgga tcatatgaag ggaatgaagg gtgcaacagg gaaaatcgat tcagctgaga
    20461 aaacgactgt ctatacggtt gattacaccc cgacaacggg cggagaaaaa gtgaaaaatc
    20521 acaagtgggt aacagaaagt gaactatctt caaaataaag gcagaatatg atgatgaact
    20581 gttaaacaaa ttggccctat ccaatatgtt taacagttta tttttattgt gctttgatat
    20641 ggccggaaga gagagcgcgt ttccactatt cggtcacgca aaaaaatttg cggttttttt
    20701 gcgcttccaa acaaaacaaa aatgataaaa tatgacatat atagaatgat gaagggaggg
    20761 gttttcaaac gtgacaggcg tcatatcttc ttccattgga gaaaagatta atgaatggta
    20821 catgtacata cgccgattca gcataccgga tgcggaatat ttacgaagag aaatcaaaca
    20881 agagctggat caaatagaag aagaccagga tatttatttg tattattcac tgatggaatt
    20941 ccggcacaat ctgatgcttg agtatcttga accgttagaa aaaatgcgga tagaggaaca
    21001 gccgcgactg tccgatttgc tgcttgaaat cgataaaaaa caggctcgtt taaccggact
    21061 gcttgaatac tattttaatt tcttcagagg tatgtatgag ctggaccacc gcgaatatat
    21121 attagccatt caatttttta aaaaagcaga gagcaaactg acttttgtta aagataaaat
    21181 tgataaagct gaattctttt tcaaaatgtc agaagtttat tactatatga agcaaactta
    21241 tgtgtccatg gactatgcac gtcaagcctt tgaaatatac aatgaacaaa ctacatatgg
    21301 tatcagaatg attcaatgcc agtccctgtt tggagctaat tttttggacc tgaaacagta
    21361 tgataaagca attgctcatt tccaaaaagc ttatacactt gctgaggcag aacagcagcc
    21421 gcaactaatg ggaagaacgc tttataatat tgccctttgc aagcaaaacc aacacagctt
    21481 tgaatcagcg atagagtatg taaaaaaatc tattcatgta tttgaaaaat ctaaaatgct
    21541 tccttcactg ccacaagcct ttttcctaat tacacaaatt tattttaaat taggaaagat
    21601 tgataacgct
//
