LOCUS       NZ_JAGPXN010000016     21065 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Micromonospora sp. C31 C31_contig_16, whole genome shotgun sequence.
ACCESSION   NZ_JAGPXN010000016
VERSION     NZ_JAGPXN010000016.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora sp. C31
  ORGANISM  Micromonospora sp. C31
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 150104)
  AUTHORS   Sahin,N., Saygin,H. and Ay,H.
  TITLE     Plant growth-promoting actinobacteria from halophytes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 150104)
  AUTHORS   Sahin,N., Saygin,H. and Ay,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2021) Molecular Biology and Genetics, Ondokuz
            Mayis University, Kurupelit, Samsun 55139, Turkey
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. APR-2021
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 145x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018070575.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 02:57:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,539
            CDSs (total)                      :: 5,480
            Genes (coding)                    :: 5,357
            CDSs (with protein)               :: 5,357
            Genes (RNA)                       :: 59
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 123
            CDSs (without protein)            :: 123
            Pseudo Genes (ambiguous residues) :: 0 of 123
            Pseudo Genes (frameshifted)       :: 23 of 123
            Pseudo Genes (incomplete)         :: 110 of 123
            Pseudo Genes (internal stop)      :: 3 of 123
            Pseudo Genes (multiple problems)  :: 12 of 123
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:03:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 126292
            Orig. end                         :: 147357
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAGPXN010000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21065
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21065
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21065
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11065](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11065
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            1058..2287
                     /locus_tag="KBX06_RS20820"
                     /old_locus_tag="KBX06_20820"
     CDS             1058..2287
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020521533.1"
                     /locus_tag="KBX06_RS20820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20820"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_210837711.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 3.5e-25, bitscore:
                     82.1, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.3e-30,
                     bitscore: 99.1, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGYAFMGAAHSQAWRTVNRVFDLPARARMALICGRDAAKVADAA
                     GRLGWDAYTTDWRELIASDDIDVVDVCTPGDSHAEIALAALAAGKHVLCEKPLANTISE
                     ARAMAAAAVTAQAAGVRSMCGFNYRRVPAVAMMRRLVADGRLGVIRHVRATYLQDWIVD
                     PQFPLVWRLQRDRAGSGALGDIGAHIIDLTQYVTGRRITGVSAITETFVRERPLPAGSS
                     GLAATVDGTGVTVDGLAAADANGSDGHRPATGPVTVDDAAVFVARLEGGVLATYEASRF
                     ATGRKNALRVEINGSLGTVAFDLERLNELEFYDATRPAAEQGFGRILVTEGEHPYMSAW
                     WPPGHLIGYEHSFTHQARDFVEAVATGVDPAPSFVDGLQVQLVLDAVTRSAELGSSWTE
                     VEPALATVAA"
     misc_feature    2552..2566
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     misc_feature    2695..2708
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.14"
                     /tool="antismash"
     misc_feature    complement(2695..2709)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.67"
                     /tool="antismash"
     misc_feature    complement(2696..2709)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.72"
                     /tool="antismash"
     misc_feature    complement(2697..2710)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.25"
                     /tool="antismash"
     misc_feature    complement(2698..2711)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.78"
                     /tool="antismash"
     misc_feature    2707..2721
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.19"
                     /tool="antismash"
     misc_feature    complement(2711..2724)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.69"
                     /tool="antismash"
     gene            2769..3929
                     /locus_tag="KBX06_RS20825"
                     /old_locus_tag="KBX06_20825"
     CDS             2769..3929
                     /GO_function="GO:0004512 - inositol-3-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006021 - inositol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783813.1"
                     /locus_tag="KBX06_RS20825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20825"
                     /product="inositol-3-phosphate synthase"
                     /protein_id="WP_210837647.1"
                     /transl_table=11
                     /translation="MRTGVWLVGARGSVATTSIVGALALRSGLTGPTGCVTELPDLRGP
                     ALPAFTDLVFGGHDVVTTPLTKRAEALATAGVLPGRLVTALPDELAAVEDELRPAPAGG
                     SQAERAAAVVRDLTDFRRRHGLDRVVVVNVSATEPAARPHPGHADPGALAAALAGGDEV
                     LPPSSLYAYAAVRAGCPYVDFTPSTGLRLPALAALAAECGIPYAGHDGKTGETLVKSVL
                     APMFAMRHLAVRSWSGVNLLGGGDGATLADPAANAAKVESKQRVLGETLGHVPQGGTRI
                     EYVEALGDFKTAWDLVTFAGFLGTGMRMEFTWHGCDSALAAPLVLDLARLTAAAHAAGH
                     TGPLTDLAFFFKDPLGASTHSLAEQWTRLCGFTRRLHAGGTDAAPR"
     gene            3913..4845
                     /locus_tag="KBX06_RS20830"
                     /old_locus_tag="KBX06_20830"
     CDS             3913..4845
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463810.1"
                     /locus_tag="KBX06_RS20830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20830"
                     /product="SCO3242 family prenyltransferase"
                     /protein_id="WP_210837649.1"
                     /transl_table=11
                     /translation="MPRLADLAELVRAPAALSVPGDVVAGAAAAGTLGRRTPALAAASV
                     LLYWAGMAANDWADRRLDAVERPERPIPSGRVAPGVALGLAAGLTAAGVALATAAGGRR
                     AAAVAVPLAAAVWGYDLAAKSTPAGPAVMAACRGLDVLLGATGGRVRTAVPAAATVAAH
                     TWTVTALSRREVTGADAALPLRTLAGTALVAASAGVPPRPVRARPRVVARARPTDVPDR
                     VLRPGPGVAVALPALLAGWYAARYGAAQARAAADPRPGPVRAAVGAGITGLPALQGALA
                     ARAGAGLLGLAVAAAAPLGGHLARKISPT"
     gene            4842..5828
                     /locus_tag="KBX06_RS20835"
                     /old_locus_tag="KBX06_20835"
     CDS             4842..5828
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287906.1"
                     /locus_tag="KBX06_RS20835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20835"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_374225661.1"
                     /transl_table=11
                     /translation="MRTPPTPAPDRRGPAAAPDAPAPARAGTDAAHPDRDGLRFGYGTN
                     GFANHRLTDALAVVADLGYQGVALTLDHDHLDPFAPALARRVAAVARRLAALDLAVVVE
                     TGARYLLDPWHKHAPTLLHDDPARRIDFLRRAVRIGADLGAQAVSLWSGVRPATVAPVT
                     AWDRLVAGCATVLDAAEAAGTTLGFEPEPGMLVEDIAGWHRLRAALGDPARLGITLDIG
                     HCRCLEPRPVPECVREVAAHLVNVQIDDMRRGVHEHLEFGAGEIDFPPVLRALGDVGYR
                     GLIAVELPRHSHAAPAVAARSLDFLRAAERKAARPQPGATGRQSARR"
     gene            5865..6467
                     /locus_tag="KBX06_RS20840"
                     /old_locus_tag="KBX06_20840"
     CDS             5865..6467
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072425.1"
                     /locus_tag="KBX06_RS20840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20840"
                     /product="EboA domain-containing protein"
                     /protein_id="WP_210837651.1"
                     /transl_table=11
                     /translation="MTPDALRAALRGVPDPDWLDAALRRVAAEPAAIDRSFPAAGRRCG
                     RAPLPAAPGWSADEAVRALLLAALPADHAAHAESRYRHGDAAEKRAVLKALPLLPIGAA
                     GVPLLHDAIRTNDTRLLTAALGPYARHLDPAAWRQAVLKCVFTGVPLAVVHDLDARADG
                     ELAAMLGALAAERHAAGRGLPADATDLLTRLRANQEA"
     gene            6467..7330
                     /locus_tag="KBX06_RS20845"
                     /old_locus_tag="KBX06_20845"
     CDS             6467..7330
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072424.1"
                     /locus_tag="KBX06_RS20845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20845"
                     /product="TatD family hydrolase"
                     /protein_id="WP_210837653.1"
                     /transl_table=11
                     /translation="MRIFDPHIHMTSRTTDDYERMAAAGVRAVVEPAFWLGQPRTSPAS
                     FADYFDSLIGWEPFRAGQFGVRHHATVALNPKEANDPRCRPVLDLLPRYLEKDAVVAVG
                     EIGYDSMTPQEDEAFAAQLALAVAHDLPALVHTPHRDKARGVERSLAVVAESGIGPGRV
                     VLDHLNEVTVGLVRDTGCWLGFSIYPDTKMSPPRMVELLRAYGTERMLVNSAADWGRSD
                     PLLTRATGEAMLLAGFTADDVDRVLWRNPVEFYGQSGRLDLTDLDAAVDAGTGTWAGNS
                     ILRGGS"
     gene            7330..8526
                     /gene="eboE"
                     /locus_tag="KBX06_RS20850"
                     /old_locus_tag="KBX06_20850"
     CDS             7330..8526
                     /codon_start=1
                     /gene="eboE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735338.1"
                     /locus_tag="KBX06_RS20850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20850"
                     /product="metabolite traffic protein EboE"
                     /protein_id="WP_210837656.1"
                     /transl_table=11
                     /translation="MRLRHPGGGTVHLGYCTNVHPAEDLAGILRQLDTHAVPVREALGA
                     DLLGLGLWLAAPVAAELAADPAARRRLRAELTVRGLEVVTLNGFPYAAFQAPVVKGDVY
                     RPDWTTPARLAYTLDLARVLADLLPDDAARGSVSTLPLAWRQPWDAARADAARRRLDEL
                     AAGLAAVERQTGRPVRVGFEPEPGCVVESTGQAVAALSGVDSDRIGVCLDLAHLACAWE
                     EPADALRRLRTAGLPVVKVQVSAAIEAPAGATSALRRWVEPRFLHQTRAAGCAGAADPA
                     HPAHAADDLDAALDARLPGPWRVHYHVPLHAPPEPPLGSTLPVLRAALAALYAGPAPGC
                     DHLDVETYTWGVLPAARRPRTDAELAVGIAAELAFARAELVALSLAPADDRHDSGVPA"
     gene            8523..10004
                     /locus_tag="KBX06_RS20855"
                     /old_locus_tag="KBX06_20855"
     CDS             8523..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463799.1"
                     /locus_tag="KBX06_RS20855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20855"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_307854702.1"
                     /transl_table=11
                     /translation="MSRRLVVLDVVGLTPRLLAHMPRLRAVADAGFRAELGTVLPALTC
                     PVQSTFLTGALPAGHGIVGNGWYFRDLGEVLLWRQHHALVGGEKLWQAARRVEPGWTVA
                     NVCWWYAMGADVDWTVTPRPVYRADGRKEPDCYTDPPELHDALTDRLGTFPLFSYWGPG
                     AGLASSAWICRAAELILAEQSPDLTLVYVPHLDYDLQRHGPSSPRAAVAAAELDEVLGP
                     LLDAARARDATVVVLSEYGITDVSRPVDVNRALRAEGLLRVHTQAGMEYLDPWTSRAFA
                     VADHQVAHVYVRDPADVPAVAALCAGLPGVAEVLDADGRAAYGLDHPRAGELVLVAEPD
                     AWFTYYYWLDDARAPDFARLVEIHRKPGYDPAELFFDPAAPSAAKRRAAVALARRKLGM
                     RYLMSVVGLDAGARAVRGSHGRLPADPADGPVLLCSDASAARGRVAATEVKALLLELAG
                     LASPASDAVAPPRRGGPPPAVPSAPAATGRTGEGP"
     gene            10001..11065
                     /locus_tag="KBX06_RS20860"
                     /old_locus_tag="KBX06_20860"
     CDS             10001..11065
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287901.1"
                     /locus_tag="KBX06_RS20860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20860"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_210837658.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-40, bitscore:
                     132.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVAVAPTDTSGLRARFDAALAAFLDRQGRDWPDGAPRGVFTALH
                     RFVLAGKRLRPLFCYWGWRGAGGADGAPIVAAAAALELFHAFALIHDDILDGSDRRRGG
                     PSVHRLFADLHARSSWRGDPEAYGRDTALLCGDLCAAWSDQMFHECGLDVGRVHRGYAV
                     FALMRTEVIAGEYLDLVSGVGDGSVASALTVVRMKAARYTVTRPLQIGATLAGAGPERV
                     AALAEFGDPLGDAFQLRDDVLGIFGDPTVTGKSVLDDLREGKPTVMMALARGAADRAQA
                     ARLRELFGNPALDGDGAAELRKIIEGTGARARIEGMIRVRAEAALAALSSAPVTAEARA
                     ALTELAARAVDRPR"
     gene            11377..14241
                     /locus_tag="KBX06_RS20865"
                     /old_locus_tag="KBX06_20865"
     CDS             11377..14241
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463796.1"
                     /locus_tag="KBX06_RS20865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20865"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_210837660.1"
                     /transl_table=11
                     /translation="MSTQDAPTHRLRRRLCAASALLLAATAGTVALGTGPAALGGPTPA
                     QAHPIVGTDFQQVTLAKGVAEVGEPMTITVLPDRSVLHTARNGTVRRTDSAGTTSVIGT
                     VPVYTHDEEGLQGIAADPGFATNRHIYLYYAPPLATPSGDAPATGSDFSAWQGVNRLSR
                     FTLNADFTMNTGSRVDILDVPADRGICCHVGGDIDFDAAGNLYLSTGDDTNPFDSAGYA
                     PIDERTNRNPAYDAQRTAANTNDLRGKILRIKVNANGTYSIPAGNMFVDSDTRTRPEIY
                     AMGFRNPFRMSVDRATGIVYVGDYGPDAGTTGARGPSGQVEFNRVTGPGNYGWPYCTGT
                     NTATETYAEWDFAAGTAGAKFNCSGGPTNNSFRNTGLPTLPGAKPAWIRYAGDAGTPPE
                     FGGGSESPMAGPVYRYDAALNSTTKFPQSFDGQFFAGELGRGWVKPIHLNADGSPGGID
                     TFPWNGKQIMDMAFGPEGALYILDYGTGYFNGDANSALYRYDYIAGGNRAPTAVAAADK
                     TSGTAPLTVNFSSAGSTDPEGGALTYSWAFGDGTSSTAANPSKTYTANGTYRVTLTVRD
                     PQGATGTANVQIGVGNTAPTVTINSPANGRLFSYGDTVPFSITVTDPEDGAIDCTKVKM
                     TYVLGHDNHGHQITSKNGCSGSITIPVDGEHDDAANIFAIFDAEYTDAGGLTTHKQHTL
                     QPRKRQAEHFKTSSGVGTFDKATAEGGRTVGDIHNGDWIAFEPYRIDNATSFSARVSSA
                     GAGGTLQVRAGSPTGTVLGSATVPVTGAWDTFTTVSGSISGAPASTGTLYLTFAGTGTG
                     ALYDVDTFAFTTGAAVRTGPVVGLGGKCLDVRNAATADGTQIQIHGCNGTAAQTWTVTP
                     NSTVKALGKCLDISGGGSADGTKIQLYGCNGTGAQNWSAQADGTLKNPQTGKCLDVSGN
                     TAADGQPVHLWTCHTGANQKWALP"
     gene            14317..16434
                     /locus_tag="KBX06_RS20870"
                     /old_locus_tag="KBX06_20870"
     CDS             14317..16434
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013735334.1"
                     /locus_tag="KBX06_RS20870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20870"
                     /product="ThuA domain-containing protein"
                     /protein_id="WP_210837662.1"
                     /transl_table=11
                     /translation="MPRLLRPLLGAATAVLAVLACTTPATSAPSASAADAPYDVLVFSK
                     TAGFRHDSIAVGTQAIRDLGAANNFTVTATEDATQFTTANLSRYEAVVFLNTTGDVLDG
                     AQQSAFESYIGAGGGFVGVHAAADTEYGWSFYGNLVGAYFASHPHIQQANVKAENRAHA
                     ATAHLPQTWTRTDEWYNYQTNARSTARVLATLDESSYTGGSMGADHPHSWCKTYSGGRS
                     FYTGGGHTQASYAEPAFRAHLLGGIRYAAGRAKADCRPETGYTALYNGSTSGWSQAGPG
                     SFSNADATLTSVGGMGLYWYSAKQFTNYSLKLDWRLAGDDNSGVFIGFPPSSDPWSAVN
                     SGYEVQIDATDAADRTTGAVYTFKSADIAARDAALNPPGEWNTYELLVEGERLQVFLNG
                     VRINDFTNTDPARSLAGHIGLQNHGTGDDASFRNIRIKELGVNPPGGNTTVQAEAFSSA
                     AGVAPFTKAGANGGQTLGHIDPGDWAAYAGVDLSGVTSLRARVVSGGPGGTLQVRTGST
                     TGTVLGSVAVPNTGGWNTFADVTTTLSGVPSGTRDLYLTFTGSGTGLFDVDDFTLVRTG
                     GSGGVGPIRGLAGKCLDVRNGATADGTQIQIQTCNGSAAQTWTVTPNSTVKALGKCLDI
                     SGGASADGTKIQLWTCNGTGAQNWSAQADGTLRNPQTGKCLDVSGNNPADGQAVHLWTC
                     HTGANQKWTLP"
     gene            16743..17750
                     /locus_tag="KBX06_RS20875"
                     /old_locus_tag="KBX06_20875"
     CDS             16743..17750
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463784.1"
                     /locus_tag="KBX06_RS20875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20875"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_210837664.1"
                     /transl_table=11
                     /translation="MARPITLFTGQWADLPFDEVCRLASEWGYDGLEIACWGDHFEVDR
                     ALADDSYVERKRETLAKHNLKVFAISNHLVGQAVCDHPIDERHQGILPARIWGDGEPEG
                     VRRRAAEEVKDTARAAAKLGVDTVVGFTGSSIWHTLAMFPPVPPSMIERGYQDFADRWN
                     PILDVFDEVGVRFAHEVHPSEIAYDYWTTKRALEAVGHRPAFGLNWDPSHFVWQELDPV
                     NFIFDFADRIYHVDCKDAKVRTGDGRRGRLASHLPWADMRRGWDFVSTGHGDVPWEDCF
                     RALNAIGYAGPISIEWEDAGMDRLVGAPEALQFVRRLAFDAPAAAFDAAFSSKD"
     gene            complement(17916..18314)
                     /locus_tag="KBX06_RS20880"
                     /old_locus_tag="KBX06_20880"
     CDS             complement(17916..18314)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463781.1"
                     /locus_tag="KBX06_RS20880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20880"
                     /product="hypothetical protein"
                     /protein_id="WP_210837666.1"
                     /transl_table=11
                     /translation="MRGKMMFLGGLAAGFVLGARAGREKYEELVIRGRKVLDHPTVQEA
                     AGVAQAQATRLYSEGKDKLGQSKLGEKLNTNGQKQELTAADDAFAGTPATVGAKNATGS
                     SSTTATPGSTSATPRNKPSGSGTNGSTL"
     misc_feature    18436..18456
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     tRNA            18589..18661
                     /anticodon=(pos:144914..144916,aa:Asn,seq:gtt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="KBX06_RS20885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="KBX06_20885"
                     /product="tRNA-Asn"
     gene            18589..18661
                     /locus_tag="KBX06_RS20885"
                     /old_locus_tag="KBX06_20885"
     misc_feature    18639..18652
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
     gene            18930..20168
                     /locus_tag="KBX06_RS20890"
                     /old_locus_tag="KBX06_20890"
     CDS             18930..20168
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463777.1"
                     /locus_tag="KBX06_RS20890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_20890"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_210837668.1"
                     /transl_table=11
                     /translation="MLAETDVIVVGGGLAGLAAARRLHRAGVPWRLLEAAARLGGRVAT
                     DAVDGYLLDRGFQVLNTAYPRLGTLLDVDRLRLGHFTSGVLVRKGDRLTRLVNPLREPT
                     GGPATALAGVGSLLDRLRFAALATGCATLPKTRLLAAEETTTETALRRAGLSDAIVEEL
                     LRPFLSGVLVGRELETSSHVLAMVLRSFARGRIGLPAEGMAALPRAVADPLPAELIDLD
                     TPVAEVAPGRVRTQAGDIRCRAVVVAVDPPAAATLLPGLPAVRMHSYTTYYHSTPEPPL
                     DEPILLLDGDRREIVANTVVVSRAAPTYAPAGRHLVATSVVGPSAPPEPTVRAELTRLY
                     GRSTADWTHLTTVSIPDALPAAPPPQGRLRKPVALGDGLFVAGDHRDSPSIQGALASGW
                     RAAGAVLSELRTG"
     misc_feature    complement(20672..20687)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.44"
                     /tool="antismash"
ORIGIN
        1 ccgccgtcgg cgccggcgtg ctgctcgccg gctgcaccag caacgagagc cagccgaccg
       61 aggcgcagac caaggcggcg ggtgcgccgg gcggcaacag cgagcccggc aagcgcgtcg
      121 tcatcggctt ctccgccccg gccgcggacc acggctggat cgccgccatc accaacaacg
      181 ccaaggcgca ggccgggacg tactccgacg tggagttcaa gtcggtcgag gccggcgcgg
      241 acgcggcggc ccagcgggcg gcgctgtcca cgctgatctc gcagaagccg gacgtgatcg
      301 tgttgctgcc gcacgacggc aaggaactca acgcgttcgg cctggaggcg atgaaggccg
      361 gcgtgccggt ggtcaacctg gaccgggcct tccccgacgc gcgggcctac cggctccaga
      421 tcaagggcga caactacggc atgggggtgg ccgccgccac ctacatgatc gagcagttca
      481 aggccaaggg cgtcagcaac ccggtgatcg gcgagatcgc cggcatggac gagctggagc
      541 tgacccagga gcggtcgaag ggcttcgccg acaccctgac ggcgagcggc ttcaaggtcg
      601 ccaaccgtcg ggcggcccgc ttcacggccg actcggggca gcaggaggcg gcgcagctgc
      661 tccaggcgct gccgaagatc gacgcgctct ggaaccacga cgacgaccag ggcatcggcg
      721 tgctggccgc ggtgaaccag agtggccgca aggagttctt catggtcggc ggcgccggct
      781 cgaagaaggc gatggaggac atccaggcgg acaacacggt gctgaaggcc accgtgacct
      841 acagcccttc gatggcctcc tcggccgtct cgctggcccg gctgatcggc cagggcaggg
      901 gcatgtccga cctggtggaa cttcaggtac ccaaggagat catcctcgcc tcggagacga
      961 tcaccaagga gaacgcgggc gactacctca agctcgggtt ctgacacacg gggggagacc
     1021 caccttgtcc acgacagaca gagaactgcg ggtcggcatg gtcggctacg cgttcatggg
     1081 cgccgcacac tcgcaggcgt ggcgcaccgt gaaccgggtg ttcgacctgc cggcgcgggc
     1141 ccggatggcg ttgatctgcg gccgggacgc cgcgaaggtg gccgacgccg ccggccggct
     1201 gggctgggac gcgtacacga ccgactggcg ggagctgatc gcctccgacg acatcgacgt
     1261 ggtcgacgtc tgcacaccgg gcgacagcca cgccgagatc gccctcgccg cgttggccgc
     1321 cggcaagcac gtgctgtgcg agaagccgtt ggccaacacg atctccgagg cccgggcgat
     1381 ggccgccgcg gcggtcaccg cgcaggccgc gggggtgcgg tcgatgtgcg ggttcaacta
     1441 ccgacgggtg ccggcggtgg cgatgatgcg ccggctcgtc gccgacgggc ggctcggggt
     1501 gatccggcac gtccgggcga cgtacctgca ggactggatc gtggacccgc agtttcccct
     1561 ggtctggcgg ttgcagcggg accgggccgg ctccggcgcg ctcggcgaca tcggcgcgca
     1621 catcatcgac ctgacccagt acgtcacggg ccggcggatc accggggtca gcgcgatcac
     1681 cgagacgttc gtcagggaac ggccactgcc ggccgggtcg agcggactgg cggcgacggt
     1741 ggacgggacg ggggtgacgg tggacgggct ggcggcggcc gacgccaacg gctccgacgg
     1801 tcaccgcccg gccaccgggc cggtcaccgt cgacgacgcg gcggtcttcg tggcccggct
     1861 cgagggcggg gtgctggcca cgtacgaggc gagccgcttc gccacgggcc gcaagaacgc
     1921 cctccgggtg gagatcaacg gctcgctggg cacggtggcc ttcgacctgg agcgcctcaa
     1981 cgagctggag ttctacgacg cgacgcggcc cgccgccgag caggggttcg gtcgcatcct
     2041 ggtgaccgag ggggagcatc cgtacatgtc cgcgtggtgg ccgccggggc acctcatcgg
     2101 ctacgagcac tccttcaccc accaggcgcg ggacttcgtc gaggcggtcg ccaccggcgt
     2161 cgacccggcc ccctccttcg tcgacgggtt gcaggtgcag ctcgtgctgg acgcggtgac
     2221 ccggtcggcg gagctgggct cctcgtggac cgaggtggag ccggcgctgg ccacggtcgc
     2281 cgcctgatcc gcctccggtg ccgaccggcg agggaccggc cgcggttgcg ccccgcggcc
     2341 gggacgaggt cggcgccgga gggtgtgccc accgggccgg tggtccggtg ggcacgagca
     2401 gaacggtcgt ccggtgcggc cggaccggga ttccccggtc gcaccggagg accgtcacca
     2461 cccggcgacg ccgccggggg tgtcacccca cgacgtccgg tcggtgcgcg ccgtcgtccc
     2521 gaccggcggg tgcgggggag gcagggacgg gacgccgacc ggccctgcct gccagccccg
     2581 tccgtccgcg cccgcaccgg gatccgggcc gggtcgtcgc cgccgacgtc gacaccggac
     2641 cggtgggctc ctcccggggc ggccggcgga cggggcccat ctgcatagat gcatatcttt
     2701 ctgaacaaac ttctgatatc tatataactc aatgcacggc tggttcctcc tgatcgggaa
     2761 ggagcaccat gcgtacgggt gtctggctgg tgggggcgcg cggctcggtc gcgaccacca
     2821 gcatcgtggg ggcgctcgcc ctgcggtccg ggctcaccgg cccgaccggc tgcgtcaccg
     2881 agctgcccga cctgcgcggg cccgccctgc cggccttcac cgacctggtc ttcggcgggc
     2941 acgacgtcgt caccaccccg ctgacgaagc gggccgaggc cctggccacc gccggcgtgc
     3001 tgcccggccg actggtcacc gccctccccg acgaactggc cgccgtcgag gacgagctgc
     3061 gcccggcccc tgccggcggc agccaggcgg aacgggccgc cgcggtcgta cgggacctca
     3121 ccgacttccg ccgccggcac gggctggacc gggtggtggt ggtcaacgtc tcggccaccg
     3181 aaccggccgc ccgcccgcat ccggggcacg ccgacccggg cgcgctggcc gccgcgctcg
     3241 ccggtggcga cgaggtgctg ccgcccagct ccctctacgc gtacgcggcg gtgcgcgccg
     3301 gctgcccgta cgtcgacttc accccgtcca ccgggctgcg gctgccggcc ctggcggcgc
     3361 tggccgccga gtgcgggatc ccctacgccg ggcacgacgg caagacgggg gagaccctgg
     3421 tcaagtccgt gctcgcgccg atgttcgcga tgcggcacct agcggtgcgc tcctggtccg
     3481 gggtcaacct gctcggcggc ggcgacggcg ccaccctcgc cgacccggcg gccaacgcgg
     3541 ccaaggtgga gagcaagcaa cgggtgctcg gcgagaccct cggccacgtc ccgcagggcg
     3601 gcacccgcat cgagtacgtc gaggcgttgg gcgacttcaa gaccgcgtgg gacctggtca
     3661 ccttcgccgg gttcctcggc accgggatgc ggatggagtt cacctggcac ggctgcgact
     3721 cggccctggc cgcacccctc gtgctggacc tggcccggct caccgccgcc gcgcacgccg
     3781 ccggccacac cggccccctc accgacctcg ccttcttctt caaggacccg ctcggcgcgt
     3841 ccacccactc gctcgccgag cagtggaccc ggctgtgcgg gttcacccgc cggctgcacg
     3901 cggggggcac cgatgccgcg cctcgctgac ctcgccgagc tggtccgggc gccggccgcg
     3961 ctgtcggtgc ccggggacgt cgtcgccggg gcggcggcag ccggcacgct cgggcggcgt
     4021 acgcccgcgc tggccgccgc gtccgtcctg ctctactggg cggggatggc ggccaacgac
     4081 tgggccgacc gccggctgga cgccgtcgaa cgccccgagc ggcccatccc cagcggccgg
     4141 gtcgcccccg gggtcgcgct cggcctcgcc gccgggctca ccgccgccgg cgtcgcgctg
     4201 gccaccgccg ccgggggcag gcgcgccgcg gcggtcgccg tcccgctcgc cgccgccgtc
     4261 tgggggtacg acctggcggc gaagtcgacc cccgccgggc cggccgtgat ggccgcctgc
     4321 cgagggctgg acgtgctgct gggcgcgacg ggcggccggg tgcgcacggc ggtaccggcg
     4381 gcggccaccg tcgccgcgca cacctggacg gtcaccgcgc tctcccgacg ggaggtcacc
     4441 ggcgccgacg ccgcgctgcc gctgcgtacc ctcgccggca ccgccctggt cgccgcgagc
     4501 gccggagtgc cgccgcgccc ggtccgcgcc cggccccggg tcgtcgcccg cgcgaggccc
     4561 accgacgtgc cggaccgcgt cctccgcccg ggccccggcg tcgcggtcgc gctgccggcg
     4621 ctgctggccg gctggtacgc ggcccggtac ggcgccgccc aggcccgggc ggcggccgac
     4681 ccccggcccg gcccggtgcg ggcggcggtg ggagcgggga tcaccgggct gcccgcgttg
     4741 cagggcgccc tcgccgcccg cgccggggcc gggctgctgg gcctggcggt ggcggcggcc
     4801 gcgccgctcg gtggccacct ggcgcggaag atctccccga cgtgaggacc ccaccgaccc
     4861 ccgcaccgga ccgccggggc ccggccgccg ccccggacgc gcccgcgccc gcacgcgccg
     4921 gcaccgacgc ggcccacccg gaccgcgacg gcctgcggtt cggctacggg accaacgggt
     4981 tcgccaacca ccggctgacc gacgcgctcg ccgtcgtcgc cgacctgggc taccagggcg
     5041 tcgcgctcac cctggaccac gaccacctcg acccgttcgc gcccgcgctg gcccggcggg
     5101 tggccgccgt cgcccgccgg ctcgcggcgc tcgacctcgc cgtggtcgtc gagaccggcg
     5161 cccgctacct gctcgacccg tggcacaagc acgccccgac gctgctgcac gacgacccgg
     5221 cgcggcggat cgacttcctg cgccgggccg tacgcatcgg cgccgacctg ggcgcgcagg
     5281 ccgtctccct ctggtccggc gtacgccccg ccacggtcgc gccggtgacc gcctgggacc
     5341 ggctggtcgc cggctgcgcg acggtgctcg acgccgccga ggcggccggg acgactctcg
     5401 gcttcgaacc ggagccgggc atgctggtcg aggacatcgc cggctggcac cggctgcgcg
     5461 ccgcgctcgg cgacccggcc cgcctcggca tcaccctcga catcggacac tgccgctgcc
     5521 tggagccccg gccggtcccc gagtgcgtgc gcgaggtggc cgcgcacctg gtcaacgtgc
     5581 agatcgacga catgcgccgg ggtgtgcacg aacacctgga gttcggcgcc ggcgaaatcg
     5641 acttcccgcc cgtgctgcgc gccctgggcg acgtcggcta ccggggcctg atcgccgtgg
     5701 aactgccccg gcactcgcac gccgcccccg ccgtcgcggc ccgctcgctc gacttcctgc
     5761 gcgccgccga gaggaaagcg gcgcgaccgc aaccgggtgc gaccgggagg caatcggcgc
     5821 gacggtgacg ccggccacgg cggaggcacg agagaggaga cgggatgaca ccggatgcac
     5881 tgcgggccgc gctgcggggc gtacccgatc ctgactggct cgacgcggcg ctgcgccggg
     5941 tggcggccga gccggcggcc atcgaccggt cgttcccggc cgccgggcgg cgctgcggcc
     6001 gggcgccgct gcccgccgca cccggctgga gcgccgacga ggcggtccgg gccctgctgc
     6061 tggccgcgct gccggccgac cacgccgcgc acgcggagtc ccgctaccgc cacggcgacg
     6121 ccgccgagaa gcgggccgtg ctcaaggccc tgccgctgct gccaatcggc gcggcggggg
     6181 tgccgctgct gcacgacgcg atccgcacca acgacacccg gctgctgacc gccgccctcg
     6241 gcccgtacgc ccggcacctc gacccggccg cctggcggca ggcggtgctc aagtgcgtct
     6301 tcaccggggt gccgctggct gtggtgcacg acctcgacgc ccgcgccgac ggcgaactcg
     6361 ccgcgatgct cggggcgctg gccgccgagc ggcacgccgc cgggcgcggc ctgccggcgg
     6421 acgcgaccga cctgctcacc cggctgcgcg cgaaccagga ggcgtgatgc gcatcttcga
     6481 cccgcacatc cacatgacct cgcggaccac cgacgactac gagcggatgg ccgccgccgg
     6541 cgtccgggcg gtggtggaac cggcgttctg gctcgggcag ccccgcacca gccccgcctc
     6601 cttcgccgac tacttcgact cgctgatcgg ctgggagccg ttccgggccg ggcagttcgg
     6661 cgtgcggcac cacgccacgg tcgcactgaa cccgaaggag gccaacgacc cgcgctgccg
     6721 cccggtgctc gacctgctgc cgcgctacct ggagaaggac gccgtggtgg cggtcggcga
     6781 gatcggctac gactcgatga ccccgcagga ggacgaggct ttcgccgccc agctcgccct
     6841 ggccgtggcg cacgacctgc cggcgctggt gcacaccccg caccgggaca aggcacgcgg
     6901 cgtcgagcgc agcctcgcgg tggtggccga gtcggggatc ggtccgggcc gggtggtgct
     6961 cgaccacctc aatgaggtga cggtggggct ggtccgcgac accggctgct ggctgggctt
     7021 ctccatctat cccgacacca aaatgtcgcc gccgcgcatg gtggagctgc tgcgggcgta
     7081 cgggacggag cggatgctgg tcaactcggc ggccgactgg ggacgctccg acccgctgct
     7141 gacccgggcc accggcgagg cgatgctgct ggccggcttc accgccgacg acgtggaccg
     7201 ggtgctgtgg cgcaacccgg tcgagttcta cggccagtcg gggcggctcg acctgacgga
     7261 cctggacgcc gccgtcgacg ccgggacggg cacgtgggcc ggcaactcga tcctgcgcgg
     7321 cggcagctga tgcggctgcg gcaccccggc ggcggcaccg tccacctcgg ctactgcacc
     7381 aacgtgcacc ccgccgagga cctcgccggc atcctgcgcc agttggacac ccacgccgtg
     7441 cccgtacgcg aggcgctcgg cgccgacctg ctcggcctcg ggctgtggct ggccgccccg
     7501 gtcgccgccg agctggccgc cgacccggcc gcccgtcgcc ggctgcgcgc cgagctgacc
     7561 gtccgggggc tggaggtggt caccctcaac ggcttcccgt acgcggcctt ccaggcgccc
     7621 gtggtcaagg gcgacgtcta ccgcccggac tggaccaccc ccgcgcggct cgcgtacacc
     7681 ctggacctgg cccgggtgct cgccgacctg ctgcccgacg acgcggcccg gggttcggtc
     7741 tccaccctgc cgctggcctg gcggcagccc tgggacgccg cccgcgcgga cgccgcccgc
     7801 cgacggctcg acgagctggc ggccggtctg gcggccgtcg agcggcagac cggccggccg
     7861 gtgcgggtcg gcttcgagcc ggagcccggc tgcgtggtgg agagcaccgg gcaggccgtc
     7921 gcggccctgt ccggcgtgga cagcgaccgg atcggcgtct gcctggacct cgcccacctc
     7981 gcctgcgcgt gggaggagcc cgccgacgcg ctgcgccggc tgcgtacggc cggcctgccg
     8041 gtggtgaagg tgcaggtctc ggccgccatc gaggcgcccg ccggggccac gtcggcgctg
     8101 cgccgctggg tggagccgcg cttcctgcac cagacccgcg ccgccggctg cgcgggcgcg
     8161 gcggacccgg cccacccggc ccacgccgcc gacgacctgg acgccgccct ggacgcgcgg
     8221 ctgcccgggc cgtggcgggt gcactaccac gtgccgctgc acgccccgcc cgagccgccg
     8281 ctgggctcca ccctgccggt gttgcgcgcc gcgctggccg cgctctacgc cgggcccgcg
     8341 ccgggctgcg accacctgga cgtcgagacg tacacctggg gggtgctgcc ggccgcgcgg
     8401 cgcccgcgca ccgacgcgga gctggccgtc ggcatcgccg cggagctggc cttcgcccgc
     8461 gcggagctgg tcgccctcag tctcgcgccg gcggatgacc ggcacgacag cggggtgccg
     8521 gcgtgagccg gcggctggtg gtgctggacg tggtggggct gaccccccgc ctgctggcgc
     8581 acatgccccg gctgcgcgcg gtcgccgacg ccggcttccg cgccgagctg ggcacggtgc
     8641 tgcccgcgct gacctgcccc gtgcagtcga ccttcctcac cggggcgctc ccggccgggc
     8701 acggcatcgt cggcaacggg tggtacttcc gcgacctcgg cgaggtgctg ctctggcggc
     8761 agcaccacgc cctggtcggc ggggagaagc tgtggcaggc ggcccgccgg gtcgagccgg
     8821 gctggacggt cgccaacgtc tgctggtggt acgcgatggg ggccgacgtg gactggacgg
     8881 tcaccccccg ccccgtctac cgcgcggacg ggcgcaagga gccggactgc tacacggacc
     8941 cgccggagct gcacgacgcc ctgaccgacc ggctcggcac cttcccgctg ttcagctact
     9001 gggggccggg cgccgggctg gcgtcgtcgg cgtggatctg ccgggccgcc gagctgatcc
     9061 tcgccgaaca gtccccggac ctgacgctgg tgtacgtccc gcacctcgac tacgacctgc
     9121 aacgccacgg cccctcgtcg ccccgggcgg ccgtggcggc ggccgagctg gacgaggtgc
     9181 tcgggccgct gctggacgcc gcccgcgccc gggacgccac cgtggtggtg ctctccgagt
     9241 acggcatcac cgacgtgtcc cgcccggtcg acgtcaaccg ggcgctgcgc gccgaggggc
     9301 tgctgcgggt gcacacccag gccggcatgg agtatctcga cccgtggacc tcgcgggcct
     9361 tcgcggtggc cgaccaccag gtggcgcacg tctacgtccg cgacccggcc gacgtgccgg
     9421 cggtggcggc gctctgcgcc gggctgccgg gggtggccga ggtgctcgac gccgacgggc
     9481 gggccgcgta cgggctggac cacccacgcg ccggggagct ggtcctcgtc gccgagccgg
     9541 acgcctggtt cacctactac tactggctcg acgacgcccg cgcgcccgac ttcgcccggc
     9601 tggtggagat ccatcgcaag ccgggttacg accccgccga actcttcttc gacccggccg
     9661 caccgtcggc ggcgaagcgg cgggccgccg tggcgctggc ccgcaggaag ctcgggatgc
     9721 gctacctgat gagcgtggtg gggctggacg ccggtgcccg ggcggtcagg gggtcgcacg
     9781 ggcggctgcc cgccgacccg gccgacgggc cggtgctgct ctgctccgat gcgtccgccg
     9841 cccgggggcg ggtcgccgcg accgaggtca aggcgctgct gctggagctg gcggggctgg
     9901 cgtcgccggc ctccgacgcg gtcgcgccgc cgcgccgggg cgggccgccg ccggccgtgc
     9961 cgtccgcccc ggcggcgacc gggcgaacgg gggaggggcc gtgaccgtcg ccgtcgcccc
    10021 gaccgacacg agcgggctgc gggcccgctt cgacgcggcg ctcgccgcgt tcctcgaccg
    10081 gcagggccgg gactggccgg acggtgcgcc ccggggcgtc ttcaccgcgc tgcaccggtt
    10141 cgtgctggcc ggcaagcggc tgcgcccgct cttctgctac tggggctggc ggggcgcggg
    10201 cggcgccgac ggcgcgccga tcgtggcggc cgccgccgcg ctggagctgt tccacgcgtt
    10261 cgcgctgatc cacgacgaca tcctcgacgg cagcgaccgt cgccggggcg gaccgtcggt
    10321 gcaccggctc ttcgccgacc tgcacgcccg ctcgtcctgg cgcggcgacc ccgaggcgta
    10381 cgggcgcgac accgcgctgc tctgcggcga cctctgcgcc gcctggtcgg atcagatgtt
    10441 ccacgagtgt ggcctggacg tgggccgggt gcaccggggg tacgcggtct tcgcgttgat
    10501 gcgtaccgag gtcatcgcgg gggagtacct ggacctggtc tcgggggtgg gcgacggttc
    10561 ggtggcgagc gcgttgaccg tggtccggat gaaggcggcc cgctacacgg tcacccggcc
    10621 gttgcagatc ggcgcgacgc tggccggggc cgggccggag cgggtcgccg cgctggccga
    10681 gttcggcgac ccgctgggcg acgcgttcca gttgcgcgac gacgtgctgg ggatcttcgg
    10741 cgacccgacg gtcaccggca agtcggtcct ggacgacctg cgggagggca agccgacggt
    10801 gatgatggcg ctggcccgcg gcgccgcgga ccgggcacag gccgcgcggc tgcgggagct
    10861 gttcggcaat ccggcgctgg acggcgacgg cgccgccgag ctgcggaaga tcatcgaggg
    10921 caccggggcc cgcgcgcgga tcgagggaat gatccgggta cgggccgagg ccgcgctggc
    10981 ggccctgtcg tcggccccgg tgaccgccga ggcccgggcc gccctgaccg aactcgccgc
    11041 ccgggccgtc gaccgccccc gctgagtcgt cccgtaccgg ccgcgacttt cggcgagatc
    11101 gacaaaagtt agcgccgatt cggcggaagg tatggacaca tcgatgtgcg ccgcttaatg
    11161 tcgggcccat cacgaatctg tttcgtcgag gcggaccggc ggcgcgggaa cccatcgact
    11221 ggtgacctcc gaccgaccgg gtccgccccg tcgctcccag gtcacggccg gccgggcacg
    11281 gcacccggca ggccgagcac cccccccgct acggcatccg gcgcgacggc gcgcgcccgc
    11341 cctggcagtc actcgtcagg aagggacggc acacccatgt ccacccagga cgcccccacc
    11401 caccggctcc gacgacggct ctgcgccgcc tcggcgctgc tcctggccgc caccgccggc
    11461 acggtcgccc tcggcaccgg cccggccgcg ctgggcggcc ccaccccggc ccaggcccac
    11521 cccatcgtcg gcaccgactt ccagcaggtc accctcgcca agggcgtcgc ggaggtcggc
    11581 gagcccatga cgatcacggt gctgccggac cggtcggtcc tgcacaccgc ccgcaacggc
    11641 accgtccgcc gtacggactc cgccggcacc acctccgtga tcggcaccgt gccggtctac
    11701 acccacgacg aggaggggtt gcagggcatc gcggccgacc cgggcttcgc caccaaccgg
    11761 cacatctacc tctactacgc cccgccgctg gccaccccgt ccggcgacgc cccggcgacc
    11821 ggcagcgact tctcggcctg gcagggcgtc aaccggctct cccggttcac cctgaacgcc
    11881 gacttcacga tgaacaccgg cagcagggtc gacatcctcg acgtgcccgc cgaccggggc
    11941 atctgctgcc acgtcggcgg cgacatcgac ttcgacgccg ccggcaacct ctacctctcc
    12001 accggcgacg acaccaaccc gtttgactcg gccgggtacg cgcccatcga cgagcgcacc
    12061 aaccgcaacc ccgcgtacga cgcgcagcgc accgcggcca acaccaacga cctgcgcggc
    12121 aagatcctgc ggatcaaggt gaacgccaac ggcacgtact cgatcccggc cggcaacatg
    12181 ttcgtcgact cggacacgcg gacccgcccc gagatctacg cgatgggctt ccgcaacccg
    12241 ttccggatga gcgtcgaccg ggccaccggc atcgtctacg tcggcgacta cggcccggac
    12301 gccggcacca ccggcgcccg gggcccgagc ggccaggtcg agttcaaccg ggtcaccggt
    12361 cccggcaact acggctggcc gtactgcacc ggcaccaaca ccgccaccga gacgtacgcc
    12421 gagtgggact tcgccgccgg aaccgccggg gcgaagttca actgctccgg tgggccgacc
    12481 aacaactcgt tccgcaacac cggcctgccc accctgcccg gggccaagcc ggcctggatc
    12541 cggtacgccg gcgacgccgg caccccgccc gagttcggcg gcggctccga gtcgccgatg
    12601 gccggccccg tctaccgcta cgacgccgcg ctgaactcca ccaccaagtt cccgcagtcc
    12661 ttcgacgggc agttcttcgc cggcgaactc ggccggggct gggtcaagcc gatccacctc
    12721 aacgccgacg gctccccggg cggcatcgac acgttcccgt ggaacggcaa gcagatcatg
    12781 gacatggcgt tcgggcccga gggggcgctc tacatcctcg actacggcac cggctacttc
    12841 aacggcgacg ccaactcggc gctctaccgc tacgactaca tcgccggcgg caaccgggcc
    12901 ccgaccgccg tcgccgcggc cgacaagacc tccggcacgg ccccgctgac cgtgaacttc
    12961 tcctcggccg ggtcgaccga cccggagggc ggcgccctga cgtactcctg ggccttcggc
    13021 gacggcacca gctcgacggc ggccaacccc agcaagacgt acaccgccaa cggcacctac
    13081 cgggtcacgc tgaccgtacg cgacccccag ggcgccaccg gcacggcgaa cgtgcagatc
    13141 ggcgtcggca acaccgcgcc cacggtcacc atcaacagcc cggccaacgg ccgactgttc
    13201 agctacggcg acaccgtgcc gttcagcatc accgtgaccg acccggagga cggcgccatc
    13261 gactgcacca aggtcaagat gacgtacgtg ctgggccacg acaaccacgg ccaccagatc
    13321 acctcgaaga acggctgctc gggctcgatc accatcccgg tcgacggcga acacgacgac
    13381 gcggcgaaca tcttcgccat cttcgacgcc gagtacaccg acgccggcgg gctgaccacg
    13441 cacaagcagc acaccctcca gccgcgcaag cgtcaggcgg agcacttcaa gacctcctcc
    13501 ggcgtcggga ccttcgacaa ggccaccgcc gagggcggca ggaccgtcgg cgacatccac
    13561 aacggcgact ggatcgcgtt cgagccgtac cgcatcgaca acgcgacctc gttcagcgcc
    13621 cgggtctcct cggccggcgc cggcggcacc ctccaggtgc gggccggttc gcccaccggc
    13681 accgtgctcg gctccgcgac cgtcccggtc accggcgcct gggacacgtt caccacggtc
    13741 agcggcagca tctccggggc accggccagc accggcacgc tctacctcac gttcgccggc
    13801 acgggcaccg gcgcgctcta cgacgtggac acgttcgcct tcaccaccgg cgcggcggtc
    13861 cgcaccggcc ccgtcgtcgg gctcggcggc aagtgcctgg acgtacgcaa cgcggccacg
    13921 gccgacggca cccagatcca gatccacggc tgcaacggca ccgccgcgca gacgtggacg
    13981 gtgacgccga actcgaccgt gaaggcgctg ggcaagtgcc tggacatctc cggcggcggg
    14041 tccgccgacg gcacgaagat ccagctgtac ggctgcaacg gcacgggcgc gcagaactgg
    14101 tccgcccagg cggacggcac cctgaagaac ccgcagaccg gcaagtgcct ggacgtctcc
    14161 ggcaacaccg ccgccgacgg tcagcccgtg cacctgtgga cctgccacac cggcgccaac
    14221 cagaagtggg ccctgccctg atctgaagga agggcccctt cctatacacc aggcgttaac
    14281 agggggccct tccttacacc tcgttgggag agcgacatgc ccagactcct ccgacccctg
    14341 ctcggcgcgg ccaccgccgt cctcgccgtc ctcgcctgca ccaccccggc aacctcggcc
    14401 ccttcggcca gcgccgccga cgccccgtac gacgtgctgg tcttctccaa gacggccggc
    14461 ttccggcacg actcgatcgc ggtcggcacc caggcgatcc gcgacctcgg cgccgccaac
    14521 aacttcaccg tcaccgccac cgaggacgcc acccagttca ccaccgccaa cctgtcccgc
    14581 tacgaggcgg tggtcttcct caacaccacc ggcgacgtgc tcgacggcgc ccagcagagc
    14641 gccttcgagt cgtacatcgg cgcgggcggc ggcttcgtcg gcgtgcacgc cgccgccgac
    14701 accgagtacg gctggtcgtt ctacggcaac ctggtcgggg cgtacttcgc ctcacacccg
    14761 cacatccagc aggcgaacgt caaggcggag aaccgggcgc acgcggcgac cgcgcacctg
    14821 ccgcagacct ggacccgcac cgacgagtgg tacaactacc agaccaacgc ccgctccacc
    14881 gcccgggtgc tggccaccct cgacgagtcg tcctacacgg gcggttcgat gggggccgac
    14941 cacccgcact cctggtgcaa gacctacagc gggggccgct ccttctacac cggcggcggg
    15001 cacacccagg cgtcgtacgc cgagccggcc ttccgcgccc acctgctcgg cggcatccgg
    15061 tacgcggccg gccgggccaa ggccgactgc cggcccgaga ccggctacac ggcgctctac
    15121 aacggctcca ccagcggctg gtcccaggcc gggccgggca gcttcagcaa cgccgacgcc
    15181 accctgacgt cggtcggcgg catgggcctg tactggtaca gcgcgaagca gttcaccaac
    15241 tactcgctca agctggactg gcggctcgcc ggggacgaca actccggcgt cttcatcggc
    15301 ttcccgccgt cgagcgaccc ctggtcggcg gtgaacagcg gctacgaggt ccagatcgac
    15361 gccaccgacg cggccgaccg caccaccggg gccgtctaca ccttcaagtc cgccgacatc
    15421 gccgcccggg acgcggcgct gaacccgccg ggggagtgga acacctacga gctgctcgtc
    15481 gagggcgagc gcctccaggt cttcctgaac ggcgtgcgga tcaacgactt caccaacacc
    15541 gacccggccc gctcgctcgc cggccacatc gggctgcaga accacggcac cggcgacgac
    15601 gcctcgttcc gcaacatccg gatcaaggaa ctcggcgtga acccgccggg cgggaacacc
    15661 accgtccagg cggaggcgtt cagctcggcg gccggggtcg ccccgttcac caaggccggc
    15721 gcgaacggtg gccagaccct cgggcacatc gacccgggcg actgggccgc gtacgccggg
    15781 gtcgacctga gcggggtgac gtcgctgcgg gcgcgggtcg tctccggtgg gccgggcggc
    15841 accctccagg tgcgtaccgg atcgacgacc ggcaccgtgc tcggctcggt cgccgtgccg
    15901 aacacgggcg gctggaacac cttcgccgac gtcacgacca ccctgtccgg ggtgccgtcc
    15961 ggcacccggg acctctacct gaccttcacc ggctcgggca cggggctctt cgacgtggac
    16021 gacttcaccc tggtcaggac cggtggcagc ggcggcgtcg gaccgatccg gggcctggcc
    16081 ggcaagtgcc tggacgtgcg caacggcgcc acggccgacg gcacccagat ccagatccag
    16141 acctgcaacg gctccgccgc gcagacgtgg acggtgacgc cgaactcgac ggtgaaggcg
    16201 ctgggcaagt gcctggacat ctccggcggc gcgtcagccg acggcacgaa gatccagttg
    16261 tggacgtgca acggcaccgg tgcgcagaac tggtcggcgc aggcggacgg gacgctgagg
    16321 aacccgcaga ccggcaagtg cctggacgtc tcgggcaaca acccggccga cggtcaggcc
    16381 gtgcacctgt ggacctgcca caccggtgcc aaccagaagt ggaccctgcc ctgatccgct
    16441 gaccctggcg ttcctccccg cgatcccgtg gtccgcgccg gcacggtgtg cggaccgggg
    16501 cggacaaccg cgggatcgcg gggaggacga gggctttcgt ggggtgcccc ggcggtccta
    16561 gagtggggtc ggcgaccgtg gcggttgccg gtgaccggcg ggaggcgcaa cccggccggt
    16621 tccaggtgcg cacgcgcacc caccggtgct ccgccgtggc ccgccgccgc accgccccgg
    16681 ccggtcaccc tcgccccggt cacgcaccca cggaatcccc atcagcacag gggagaagca
    16741 ccatggcgcg acccatcacg ctcttcaccg gccagtgggc cgatcttccg ttcgacgagg
    16801 tctgccggct cgcctccgag tggggctacg acgggctgga gatcgcctgc tggggcgacc
    16861 acttcgaggt cgaccgggcg ctcgcggacg actcgtacgt cgagcggaag cgggagaccc
    16921 tggcgaagca caacctgaag gtcttcgcga tctccaacca cctggtcggc caggccgtct
    16981 gcgaccatcc gatcgacgag cggcaccagg gcatcctgcc cgcgcggatc tggggtgacg
    17041 gcgaacccga aggcgtacgc cgccgcgccg ccgaggaggt caaggacacc gcgcgggcgg
    17101 cggcgaagct gggggtggac accgtcgtcg gcttcaccgg ctcgtcgatc tggcacacgc
    17161 tggcgatgtt cccgccggtg ccgccgtcga tgatcgagcg cggctaccag gacttcgccg
    17221 accggtggaa cccgatcctg gacgtcttcg acgaggtggg ggtgcgcttc gcccacgagg
    17281 tgcacccgag cgagatcgcg tacgactact ggacgacgaa gcgggcactg gaggcggtcg
    17341 ggcaccggcc cgcgttcggg ctgaactggg acccgtcgca cttcgtctgg caggagctgg
    17401 acccggtgaa cttcatcttc gacttcgccg accggatcta ccacgtcgac tgcaaggacg
    17461 cgaaggtgcg tacgggggac ggacggcggg gccggctcgc ctcgcacctg ccgtgggcgg
    17521 acatgcggcg cggctgggac ttcgtctcca ccggccacgg cgacgtgccc tgggaggact
    17581 gcttccgggc cctgaacgcg atcggctacg ccggcccgat ctcgatcgag tgggaggacg
    17641 ccgggatgga tcgcctcgtc ggcgccccgg aggcgttgca gttcgtccgc cggctcgcct
    17701 tcgacgcccc cgccgcggcc ttcgacgccg ccttcagcag caaggactga ccggctccgg
    17761 tcgcatccgg gctaccggcg tcggggtccg cacgcgtcgc atccgggcta ccggcgtcgg
    17821 ggtccgcacg cggtcgcacc cgggccgccc gcgtcggggt ttgcacgcgg ggcgggccgg
    17881 tcacccgaag gtgaccggcc cgcccgaagg tgcgctcaga gggtgctgcc gttggtgccc
    17941 gagccggacg gcttgttacg gggcgtggcc gacgtcgacc cgggggtcgc ggtcgtgctc
    18001 gacgacccgg tggcgttctt cgcgccgacc gtggccggcg tgccggcgaa cgcgtcgtcg
    18061 gcggcggtca gctcctgctt ctggccgttg gtgttcagct tctcacccag cttcgactgg
    18121 ccgagcttgt ccttgccctc gctgtagagg cgggtcgcct gggcctgcgc gacaccggcc
    18181 gcctcctgga cggtcgggtg gtcgagcacc ttgcggcccc ggatcaccag ctcctcgtac
    18241 ttctcccgac cggcacgggc gcccaggacg aatcccgcag ccagcccgcc aaggaacatc
    18301 atctttccgc gcatggcggc tccttccgta cctgacgcgc cgtcgtccgg tgggttaccc
    18361 cgccggaggc gaccaaatcg cgcctgtctt ctctgtcggc agctaactac ccatcctgct
    18421 ctccgctcat acctccttgt gccgtgatga cgatttgtct ggttttatta tcgtgtggcc
    18481 cgggcgccga ctccgaaggt aaccccctgg accaacaccc cccggaatcc tgtattcttg
    18541 tcctcgtcgc acggcgcaca gcgagatcgg cgccggatga cgcaacggtc ccccgtagct
    18601 caattggcag agcagccggc tgttaaccgg caggtttttg gttcgagtcc aaacggggga
    18661 gcttccacac ccagacgccc gtcggccacg ccggcgggcg ttcgccgttc ctgcccccgg
    18721 gtcgggtggg cgtttccgcc acccaggggc ccgcttcccc ggcaggatgg tcgatgtcga
    18781 cctagactcc tgctgcgtcg atcgatgcgt cggttcatgg gaacgtccgc tcgctgccgg
    18841 ctgcccgcgc gccgggctgc gacaccgggc cgacgatctg gtggccgggg cgggctgccc
    18901 cggacgaacg aaggagcggg aggcgcgcga tgctcgcgga gaccgacgtg atcgtggtcg
    18961 gcggcggcct ggcagggctc gccgcggccc ggcggctgca ccgcgcgggc gtgccgtggc
    19021 ggctgctgga ggccgccgcc cgcctcggcg gccgggtcgc caccgacgcg gtcgacggct
    19081 acctgctcga tcgcggcttc caggtgctca acacggcgta cccccggctc ggcaccctgc
    19141 tcgacgtcga ccggctgcgc ctcggccact tcacctccgg tgtgctggta cgcaagggcg
    19201 accggctgac ccgcctggtg aacccgctgc gcgaaccgac cggcggcccc gccaccgcgc
    19261 tggccggcgt gggatcgctg ctcgaccggc tgcgcttcgc cgcgctcgcc acgggctgcg
    19321 ccaccctgcc gaagacccgg ctgctcgccg ccgaggagac caccaccgag accgcgctgc
    19381 gccgcgccgg cctctccgac gcgatcgtcg aggagctgct ccggccgttc ctctccggcg
    19441 tcctcgtcgg ccgggagctg gagacctcca gccacgtgct ggcgatggtg ctgcgctcct
    19501 tcgcccgggg ccgcatcggc ctgcccgccg aggggatggc cgcgctgccc cgcgccgtcg
    19561 ccgacccgct cccggcggag ctgatcgacc tggacacccc ggtcgccgag gtggcgcccg
    19621 gccgggtccg cacccaggcc ggcgacatcc gctgccgcgc cgtcgtggtc gccgtggacc
    19681 cgccggcggc ggccacgctg ctgccgggtc tgccggcggt acgcatgcac agctacacga
    19741 cctactacca cagcaccccg gagccgccgc ttgacgagcc gatcctgctc ctcgacggcg
    19801 accggcgcga gatcgtcgcc aacacggtgg tggtcagcag ggccgcgccc acgtacgcgc
    19861 cggccggtcg gcacctggtc gccacctcgg tggtgggccc gtcggccccg cccgagccga
    19921 cggtgcgggc ggaactcacc cgcctctacg gccggtccac ggcggactgg acccacctga
    19981 ccacggtgtc catccccgac gcgctgcccg ccgcgccccc gccgcagggc cggctgcgca
    20041 agccggtggc cctgggagat ggcctgttcg tcgccgggga ccaccgcgac agcccctcca
    20101 tccaaggcgc cctcgccagc ggctggcggg ccgccggagc cgtcctgtcg gagctgcgta
    20161 ccggctgaac ggtgggtcac gccccgttga agatcactta tgctcctcgc catgcccgga
    20221 accattccgc cgcccgactt cgacgccgcg gcggcgtacc cccaggtcgg tcaggtgcgc
    20281 gcggccctcg cggcccgcga ctggccggcc ctgcgcgcga tcgtcgacgg gcaggacccg
    20341 cacggccgga ccctcctcgt cggcgaggcc ggcgagaccg aggacgtcga ggagttcctc
    20401 cgggacgtgc tggccgggcg gcccgacgac gcgctcgccg gcgccctgct cgggtcgcac
    20461 ctgatccggg ccggctggcg gatccgatcg tcctaccggg cccagcacgt cagccgggag
    20521 cagttcgccc agttccacgc ccacctgcgg cgggccgagc aggtgctgat cgacgtcacc
    20581 gcccggcacc cggacgacgc ggcggcgtgg acgcagcgga tcaccaacgc gcggggactg
    20641 gagctcggcc aggccgaggc ccgccgccgc tacgaccagc tcgccaagca ccacccccac
    20701 cacctgccgg cccaggcgtc gctgctgcaa cagttctgcc cgaagtggag cggcacctgg
    20761 gaacgggcac acggcttcgc ccgggagtgt gccgacgccg ccccgcccgg cgcaccgaac
    20821 gcggtgctgg tggtcgaggc ccacctggag gaggcgctcg accacgacga cgtgagcgag
    20881 gcgggcgccc acctgcgcgg cgcgcacgtc cggcacgaga tccaccaggc ggcgcagcag
    20941 tcggtctggc accccgggtt ccggcacggc tggggttggg tctgggtgcg cagcgtcttc
    21001 gcgatggcct tctgcctcct ggaggagtac ccggcggcgg cgcagcagtt cgcggccatg
    21061 gggcc
//
