LOCUS       NZ_JAGPXN010000003     20954 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Micromonospora sp. C31 C31_contig_3, whole genome shotgun sequence.
ACCESSION   NZ_JAGPXN010000003
VERSION     NZ_JAGPXN010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora sp. C31
  ORGANISM  Micromonospora sp. C31
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 288588)
  AUTHORS   Sahin,N., Saygin,H. and Ay,H.
  TITLE     Plant growth-promoting actinobacteria from halophytes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 288588)
  AUTHORS   Sahin,N., Saygin,H. and Ay,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2021) Molecular Biology and Genetics, Ondokuz
            Mayis University, Kurupelit, Samsun 55139, Turkey
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. APR-2021
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 145x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018070575.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 02:57:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,539
            CDSs (total)                      :: 5,480
            Genes (coding)                    :: 5,357
            CDSs (with protein)               :: 5,357
            Genes (RNA)                       :: 59
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 123
            CDSs (without protein)            :: 123
            Pseudo Genes (ambiguous residues) :: 0 of 123
            Pseudo Genes (frameshifted)       :: 23 of 123
            Pseudo Genes (incomplete)         :: 110 of 123
            Pseudo Genes (internal stop)      :: 3 of 123
            Pseudo Genes (multiple problems)  :: 12 of 123
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:03:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 223350
            Orig. end                         :: 244304
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAGPXN010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20954
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10954](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10954)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            14..646
                     /gene="hisH"
                     /locus_tag="KBX06_RS07640"
                     /old_locus_tag="KBX06_07640"
     CDS             14..646
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183512.1"
                     /locus_tag="KBX06_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07640"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="WP_210833510.1"
                     /transl_table=11
                     /translation="MSRVAVLDYGSGNLRSAERALARAGADVTVTDDLVAAAEADGLVV
                     PGVGAFAACMAGIEALGAGPVIAERVAAGRPVLGICVGMQVLFEHGAEHGVVTKGLGLL
                     PGGVTRLAAARLPHMGWNTVAAPAGSVLFAGLPADSRFYFVHSYGVGDPGALAGAGATV
                     TTAHHGTDFVAAVERGPLCAAQFHPEKSADTGAALLRNWLATLSTGG"
     gene            746..1069
                     /locus_tag="KBX06_RS07645"
                     /old_locus_tag="KBX06_07645"
     CDS             746..1069
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014402.1"
                     /locus_tag="KBX06_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07645"
                     /product="hypothetical protein"
                     /protein_id="WP_210833511.1"
                     /transl_table=11
                     /translation="MSKERARRRAAREAQAARERVVRERRSARRSRRRALVRRLTPSLR
                     RGRTGRLPRHSRGERAAIVLLTLAAMALIWTFVDDLALRIALVVLLLLVLPAIVVIALD
                     RRT"
     gene            1087..1812
                     /gene="priA"
                     /locus_tag="KBX06_RS07650"
                     /old_locus_tag="KBX06_07650"
     CDS             1087..1812
                     /EC_number="5.3.1.16"
                     /EC_number="5.3.1.24"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003949 - 1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA]"
                     /GO_function="GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="priA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018813684.1"
                     /locus_tag="KBX06_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07650"
                     /product="bifunctional 1-(5-phosphoribosyl)-5-((5-
                     phosphoribosylamino)methylideneamino)imidazole-4-
                     carboxamide isomerase/phosphoribosylanthranilate isomerase
                     PriA"
                     /protein_id="WP_210833512.1"
                     /transl_table=11
                     /translation="MSLTLLPAVDVADGQAVRLVQGAAGSETTYGDPLEAALAWQRDGA
                     EWIHLVDLDAAFGRGSNAHLLAEVVRQLDVKVELSGGIRDDESLHAALGTGAARVNIGT
                     AALEDPVWCDRVCGEYGDRVAIGLDVRGRTLSARGWTRDGGDLFEVLERLDKAGATRYV
                     VTDITKDGTMRGPNLDLLREVCARTDAPVIASGGVSTLDDLRALATLEPLGVEGVIAGK
                     ALYAGAFTVAQALETLAAA"
     gene            1809..2198
                     /locus_tag="KBX06_RS07655"
                     /old_locus_tag="KBX06_07655"
     CDS             1809..2198
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462975.1"
                     /locus_tag="KBX06_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07655"
                     /product="RidA family protein"
                     /protein_id="WP_210833513.1"
                     /transl_table=11
                     /translation="MTVTRLGSGGPWESLYGYCRVVRAGDLAVTAGCTSTVDGTVTHVG
                     DAAAQTAQALRIGLDALAEVGAEPGDVVRTRMYVTDRTYADEVGRAHNAVFGAVRPAAT
                     MVVVAGLLHPDHLVEVELEAYLGDR"
     gene            2327..2770
                     /locus_tag="KBX06_RS07660"
                     /old_locus_tag="KBX06_07660"
     CDS             2327..2770
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018789360.1"
                     /locus_tag="KBX06_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07660"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_210833514.1"
                     /transl_table=11
                     /translation="MTDHLVLRRQVCFALYAASRALTDVYRPVLDEFGLTYPQYLVLLV
                     LWERDDAPTVSELGAALRLDSGTLSPLLKRLEGAGLVVRTRSARDERRVEVGLTGDGRA
                     LRHRMAEVPLRVALATGLTEAELVALRDTLTRVTETIHRQKEQ"
     gene            2776..3201
                     /locus_tag="KBX06_RS07665"
                     /old_locus_tag="KBX06_07665"
     CDS             2776..3201
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287575.1"
                     /locus_tag="KBX06_RS07665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07665"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_247685465.1"
                     /transl_table=11
                     /translation="MQVLYTASARATGDGRDGHVRTSDGTVDLDLAVPKEMGGAGGAAN
                     PEQLFAAGYAACFHSALRLVARKAKVDVSGSVVEAEVGIGANGSGGFGLAVTLLVDLPA
                     AERAAAEQVVEQAHRVCPYSNATRGNVEVALTVREAL"
     gene            3198..4199
                     /locus_tag="KBX06_RS07670"
                     /old_locus_tag="KBX06_07670"
     CDS             3198..4199
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (21-331). E-value: 2.8e-21.
                     Score: 67.9. Matches aSDomain:
                     nrpspksdomains_KBX06_RS07670_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014399.1"
                     /locus_tag="KBX06_RS07670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07670"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_210833516.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.8e-24, bitscore:
                     78.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRNREIHLASRPQGWPTADNFRLVETDVPTPGPGQIVVRNRYM
                     SVDPYMRGRMNDVKSYVPPFALDAPLDGGAVGEVVAGETEGLRPGDTVLHGLGWREYAL
                     LDAKAARKVDPDLAPVTAYLGVLGMTGLTAYAGLLEVAGMKPGETVFVSAAAGAVGSLV
                     GQIAKLRGAARVVGSAGSAAKVERLRALGFDAAFDYHDGPVRDSLKAAAPDGVDVYFDN
                     VGGDHLEAAISAMRVHGRAAICGMIAQYNDTEPPAAPRNLALVIGKRLTLRGFLVGDHG
                     HLRGEFVREMAGWLRDGKVSYDETVVDGIEDAPEAFLGLLRGENLGKMLVRV"
     aSDomain        3261..4190
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KBX06_RS07670_PKS_ER.1"
                     /evalue="2.80E-21"
                     /label="KBX06_RS07670_PKS_ER.1"
                     /locus_tag="KBX06_RS07670"
                     /protein_end="331"
                     /protein_start="21"
                     /score="67.9"
                     /tool="antismash"
                     /translation="NFRLVETDVPTPGPGQIVVRNRYMSVDPYMRGRMNDVKSYVPPFA
                     LDAPLDGGAVGEVVAGETEGLRPGDTVLHGLGWREYALLDAKAARKVDPDLAPVTAYLG
                     VLGMTGLTAYAGLLEVAGMKPGETVFVSAAAGAVGSLVGQIAKLRGAARVVGSAGSAAK
                     VERLRALGFDAAFDYHDGPVRDSLKAAAPDGVDVYFDNVGGDHLEAAISAMRVHGRAAI
                     CGMIAQYNDTEPPAAPRNLALVIGKRLTLRGFLVGDHGHLRGEFVREMAGWLRDGKVSY
                     DETVVDGIEDAPEAFLGLLRGENLGKMLV"
     CDS_motif       3636..3677
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KBX06_RS07670_0001"
                     /evalue="5.80E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="KBX06_RS07670"
                     /protein_end="160"
                     /protein_start="146"
                     /score="9.5"
                     /tool="antismash"
                     /translation="GETVFVSAAAGAVG"
     gene            4295..5062
                     /gene="hisF"
                     /locus_tag="KBX06_RS07675"
                     /old_locus_tag="KBX06_07675"
     CDS             4295..5062
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019900882.1"
                     /locus_tag="KBX06_RS07675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07675"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="WP_210833517.1"
                     /transl_table=11
                     /translation="MTVAVRVIPCLDVDAGRVVKGVNFLDLRDAGDPVELAAAYDRAGA
                     DELTFLDVTASSSDRGTMLDVVRRTAESVFIPLTVGGGVRQVADVDTLLRAGADKVGVN
                     TAAIARPELIAEIADRFGRQVLVLSLDVRRAPGGGTPSGFEVTTHGGRRGTGLDAVGWA
                     RRGAELGAGEILLNSMDADGTKAGFDLELIGAVRRVVDVPVVASGGAGEVAHFAPAIGA
                     GADAVLAASVFHFGELTVAEVKDALRGAGHPVR"
     gene            complement(5162..5623)
                     /locus_tag="KBX06_RS07680"
                     /old_locus_tag="KBX06_07680"
     CDS             complement(5162..5623)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018804515.1"
                     /locus_tag="KBX06_RS07680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07680"
                     /product="hypothetical protein"
                     /protein_id="WP_210833518.1"
                     /transl_table=11
                     /translation="MGENGWRWSDAWIFVSVVIASGAGRHRRAATSRRPEGVRLADVLS
                     TADHLNQAIPERHEVEAAVRRLVGAGLVSVTDGWFRITADGERLWRTRPSAGLATTVDT
                     VQGVLVRRHAPVSAEWQLEEADHAAAVQEYVVRSIPAPRRSPENRSRRD"
     gene            complement(5773..6429)
                     /locus_tag="KBX06_RS07685"
                     /old_locus_tag="KBX06_07685"
     CDS             complement(5773..6429)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462952.1"
                     /locus_tag="KBX06_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07685"
                     /product="YitT family protein"
                     /protein_id="WP_210833519.1"
                     /transl_table=11
                     /translation="MTPIGNLRHRSVRRLSQLYAGLVLYGVSMALMIESGLGLDPWDVF
                     HQGLSELTGLSFGIVTIAVGALVLLLWIPLRQRPGLGTVSNVLVIGLVVDAALALLPGG
                     GPLGVRAGMLVAGIVANGAATGLYIGARLGPGPRDGLMTGYVARRPGRSIRLVRTVIEV
                     AVLALGWLLGGTVGVGTVVYALAIGPLTQLFLPLFTVAGPKDRPTAGPVAPLPTA"
     misc_feature    6412..6427
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.53"
                     /tool="antismash"
     gene            6488..7945
                     /locus_tag="KBX06_RS07690"
                     /old_locus_tag="KBX06_07690"
     CDS             6488..7945
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (126-463). E-value:
                     1.1e-27. Score: 89.0. Matches aSDomain:
                     nrpspksdomains_KBX06_RS07690_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014395.1"
                     /locus_tag="KBX06_RS07690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07690"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_210833520.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.7e-27, bitscore:
                     88.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQVRGAQLARLLGQWHALPGRRRSPDYAALAGAVRGLLADGRL
                     PLGVRLPAERELAEALKISRTTVTAAYRELRESGHLASRRGAGSWTMLPGTHRVASTGL
                     WTPLDDRDMIDLGVAALAAPPELLPAARAAAEDLPRYLGGAGYHPTGIIELREAVARAY
                     TARGLPTSPDQIMVTNGTQHALDLVLRLALAPGGNVLVEAPSYPNALAALAARRARITT
                     HGLAVEEPGWDADLLLGGLRQARPKLAYLIPDFQNPTGHLMPAALRERVVATAHAVGTD
                     LVVDESFVDLPLDGTVLPPPTASFDRHSRVITIGGMSKPFWGGLRIGWVRASAPQVQRL
                     AAARVGVDMASPVLDQLVAVHLLADAPAIVAARQAQLTAQRDALLAALAQRLPEWRVTV
                     PHGGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPAADLVE
                     AVGRIAAVRYDLDRGGRSQWREPTVIA"
     aSDomain        6866..7876
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KBX06_RS07690_Aminotran_1_2.1"
                     /evalue="1.10E-27"
                     /label="KBX06_RS07690_Aminotran_1_2.1"
                     /locus_tag="KBX06_RS07690"
                     /protein_end="463"
                     /protein_start="126"
                     /score="89.0"
                     /tool="antismash"
                     /translation="LLPAARAAAEDLPRYLGGAGYHPTGIIELREAVARAYTARGLPTS
                     PDQIMVTNGTQHALDLVLRLALAPGGNVLVEAPSYPNALAALAARRARITTHGLAVEEP
                     GWDADLLLGGLRQARPKLAYLIPDFQNPTGHLMPAALRERVVATAHAVGTDLVVDESFV
                     DLPLDGTVLPPPTASFDRHSRVITIGGMSKPFWGGLRIGWVRASAPQVQRLAAARVGVD
                     MASPVLDQLVAVHLLADAPAIVAARQAQLTAQRDALLAALAQRLPEWRVTVPHGGVTLW
                     AELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPAADLVEAVGRI"
     gene            complement(8034..9860)
                     /locus_tag="KBX06_RS07695"
                     /old_locus_tag="KBX06_07695"
     CDS             complement(8034..9860)
                     /NRPS_PKS="Domain: AMP-binding (14-471). E-value: 3.3e-89.
                     Score: 291.2. Matches aSDomain:
                     nrpspksdomains_KBX06_RS07695_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475807.1"
                     /locus_tag="KBX06_RS07695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07695"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_210833521.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-89, bitscore:
                     294.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALDVPYRSIPDMFLKRVAASPDRDAFAHPAPDDSGPVWLNWEQM
                     ARRAKAVAAGLHGLGVGLEDPVAILANTRLEWVIADLGIMCAGGATTTVYPTTEPDDAT
                     YIVADSGSRVLFAEDPAQAAKIAGADLPALTHVVLFDGAADPAAAVPQLTLAELEEQGA
                     RALAAQPDLIDTLVAGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLR
                     ENDLQYLWLPLSHSFGKTLLCGAIHVGLPTYVDGRVDKLVELLSVIRPTLMCGAPRVYE
                     KVYNKAVTTAQASGGAKAKIFAWGVRVGTEKVALEQAGRPVPTGLKLKYTVAEKLVFSK
                     LQARLGGRIRVLVSGAAPLSPEIATFFAAANLPISEGYGLTETSAGNFVNPPDGLRIGT
                     VGKAMGDLECRIDTDGEILVRGRPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDADGY
                     LKITDRKKDLVKTSGGKYVAPSHIEGLFKATCPYTSQAVVIGQARNYCTMLVTLDPEAI
                     KGWAVGTPLEGRDYTEIVSSPEAKAMVEGYVAELNAKLNRWETIKKVAILPRDLTIEDG
                     EITPSLKIKRRGVESNFAGEIEKMYAGSLAEL"
     aSDomain        complement(8448..9818)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KBX06_RS07695_AMP-binding.1"
                     /evalue="3.30E-89"
                     /label="KBX06_RS07695_AMP-binding.1"
                     /locus_tag="KBX06_RS07695"
                     /protein_end="471"
                     /protein_start="14"
                     /score="291.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LKRVAASPDRDAFAHPAPDDSGPVWLNWEQMARRAKAVAAGLHGL
                     GVGLEDPVAILANTRLEWVIADLGIMCAGGATTTVYPTTEPDDATYIVADSGSRVLFAE
                     DPAQAAKIAGADLPALTHVVLFDGAADPAAAVPQLTLAELEEQGARALAAQPDLIDTLV
                     AGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLRENDLQYLWLPLSHS
                     FGKTLLCGAIHVGLPTYVDGRVDKLVELLSVIRPTLMCGAPRVYEKVYNKAVTTAQASG
                     GAKAKIFAWGVRVGTEKVALEQAGRPVPTGLKLKYTVAEKLVFSKLQARLGGRIRVLVS
                     GAAPLSPEIATFFAAANLPISEGYGLTETSAGNFVNPPDGLRIGTVGKAMGDLECRIDT
                     DGEILVRGRPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDADGYLKITDRKKDLVKT"
     CDS_motif       complement(8544..8618)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KBX06_RS07695_0002"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="KBX06_RS07695"
                     /protein_end="439"
                     /protein_start="414"
                     /score="26.8"
                     /tool="antismash"
                     /translation="GEILVRGRPVMRGYHNLPEETAAAF"
     CDS_motif       complement(9246..9305)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KBX06_RS07695_0001"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="KBX06_RS07695"
                     /protein_end="205"
                     /protein_start="185"
                     /score="23.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGRPKGVELLH"
     misc_feature    complement(9889..9904)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            complement(10001..10954)
                     /locus_tag="KBX06_RS07700"
                     /old_locus_tag="KBX06_07700"
     CDS             complement(10001..10954)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287567.1"
                     /locus_tag="KBX06_RS07700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07700"
                     /product="terpene synthase"
                     /protein_id="WP_210833522.1"
                     /sec_met_domain="T1TS (E-value: 2e-71, bitscore: 235.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTFAVSALREPPFPERQHDATERVARESTEWALGHGLISNGHGL
                     HRLHRADAAGLAGRAYPDGPVDGLRLLADLISWLFVMDDACDEDGLGASPTRLAPTVAA
                     LLDVLDGQGGRADGPVTAAGPLGEALGDLCRRARAAGGPTALLRFAGEVREYLLALLWE
                     AANREHGRVPGLAEYAQMRRHTGAVHPSFTLTELAGGTPPGAAHRTEPSLVALDLLAAD
                     LVCWCNDVFSYGKEHLSRPDAHNLVAVLAAGRTDGDESAALRAAADRFNEALSTYLATE
                     TALLTVGDDGLRTALTARRNWIRATYDWSLRAARYA"
     gene            complement(11078..11707)
                     /locus_tag="KBX06_RS07705"
                     /old_locus_tag="KBX06_07705"
     CDS             complement(11078..11707)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183502.1"
                     /locus_tag="KBX06_RS07705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07705"
                     /product="TIGR03085 family metal-binding protein"
                     /protein_id="WP_210833523.1"
                     /transl_table=11
                     /translation="MPRYARAEREALADLMQTLGPEAPTVNDGWTIRDLAAHLVLRERR
                     PDAAGGIVLPPLRGHAERVRLRIAARAWPRLLDEVRRPPAWSPVSNPVTDELANTLEFF
                     IHHEDVRRARPDWLPRDLAAGLNAALWKRCAGLARLALRRFPADVLVQAPGYGELHVGR
                     GGDSVRVAGAPGELALFLSGRQRVSRMQIDGPAALADRLRGTDLGM"
     misc_feature    11773..11787
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 17.94"
                     /tool="antismash"
     gene            11855..13729
                     /locus_tag="KBX06_RS07710"
                     /old_locus_tag="KBX06_07710"
     CDS             11855..13729
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020215714.1"
                     /locus_tag="KBX06_RS07710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07710"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_210833524.1"
                     /transl_table=11
                     /translation="MASRTSRDVLVRGLAVLGRAIREEPRIFAVAVSSSVLFGAMTVAS
                     AFVVGAVVGDVVVPAIERGAVGVGGLALAAVALFGISVLRVAGIFGRRLGAGYMQYRLQ
                     AAYRRRVTRRYLELPLAWHHRNATGTLLSNANSDVEAAWYPIAPLPFAVGTLVMLVGAV
                     ASLFVTDWALALVGLAVFPALFALNVAYSRRMAPRQARAQRLRAEVSGIAHESFDGALV
                     VKTMGREAQETDRFAARAGELRDSLVAVGRLRGVFDPLLETLPSLGTLAVLVVGTIRLR
                     QGAITVAELISVAFLFTVLAFPVRAIGWVLAELPRSVAGWDRVSRVLDATGRMPYGDTT
                     LDVSEPRPASLTFTGVRFGYEPAEAHLPGTEVLGEVSFTVPAGKTVALVGPTGSGKSTI
                     AALAVRLVDPLAGTVCLDSVDVRRLTAASLTGTAALVAQVPFVFDDTVRANVALDRAGI
                     GDDDVWAALRLAEADGFVAALPDGLDTMVGERGTSLSGGQRQRLTLARALAGRPRLLVL
                     DDATSAVDPRVEAAILAGLRSSAAGAPAASILVVAYRRATIALADEVVYLEQGRVLARG
                     RHTELLATVPGYADLVTAYEQAEVDPAKDETYDEVAPVTSGLKIEVDR"
     gene            13931..15658
                     /locus_tag="KBX06_RS07715"
                     /old_locus_tag="KBX06_07715"
     CDS             13931..15658
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018730772.1"
                     /locus_tag="KBX06_RS07715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07715"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_210833581.1"
                     /transl_table=11
                     /translation="MRRGLALSPELRVGLAGTLGLALVYMVGRAAVPVAVQQGIDNGIV
                     DGLDLGVIWTVVAVTAAVLVVTTLCGYLMMRRLFTVSETALANVRIRAFRHVHDLSMLH
                     QQSERRGSLVSRVTSDVDQITQFLQWGGVILVINLGQLAVTTLVMFAYSWQLTLVVFAA
                     FLPAVFVIRRLQRRLAGAYGVVRQRTGALLGAIGESVVGAPVIRAYGISGRTARRLDEA
                     IDGQRRAQQRAIRISVMGSSVGELAAGLALAGVVVLGVTLGADRTLSIGEVTAFLFLVT
                     LFIQPVQIATEVLNEAQNAIAGWRRVLDVLDVEPDVADPGEQGRELPAGPLDIRFAGVR
                     FAYPGGPPVLHDVSLEIPAKSRVAVVGETGSGKTTFAKLLTRLMDPTAGQVLLSGVPLE
                     RVRFASLRSRVVMVPQDGFLFDATVAENVRFARPELTDEQLAAAFTELGLADWLDALPS
                     GLHTCVGERGEALSVGERQLVALARAYVADPDLLVLDEATSAVDPATEVRLQRTLDAVT
                     RGRTTLAIAHRLSTAQAADEVIVVDRGRIVQRGPHDELVRDPESVYGLLYASWLEQTR"
     misc_feature    15736..15754
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 30.62"
                     /tool="antismash"
     gene            15768..16526
                     /locus_tag="KBX06_RS07720"
                     /old_locus_tag="KBX06_07720"
     CDS             15768..16526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072126.1"
                     /locus_tag="KBX06_RS07720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07720"
                     /product="DUF2470 domain-containing protein"
                     /protein_id="WP_210833525.1"
                     /transl_table=11
                     /translation="MRPSPAEIVRTLVAGRLPGIAHVAHRPGPHQVRHVTDPDGRVLLL
                     VPVVSDLAAALRPAAGEAAVALVLDVLDLPPAAGAPSLGRAWVSGWAARLAGDEERRAA
                     LDFADVEPAGDLLDVGTRFRLHRFEVVEARWERGDTVRRVDPEAYAEAEPDPLHAVEAE
                     LLADLAGHHAAEVAGYLGRQLGLADDAPDAAPRVVRIDRYGLLVTHGRPGARRRVRLAF
                     PRPLDCRAELTRLLHPLVGRHASPRHADHA"
     gene            complement(16555..17163)
                     /locus_tag="KBX06_RS07725"
                     /old_locus_tag="KBX06_07725"
     CDS             complement(16555..17163)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183498.1"
                     /locus_tag="KBX06_RS07725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07725"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_210833526.1"
                     /transl_table=11
                     /translation="MARRTGRRPGNPDTRQAILDAARAAFAERGFDGASIRAVAAAAQV
                     DPALVHHYFGSKDRLFLAAMHAPVDPAELLPSVLAGDRAGLGERLVRTFLGVWDSPAGT
                     AGVALLRSAVSNEWTARLLREFLVTQVLRRVLDQLDVDPAELPLRGSLVASQMIGLAVM
                     RYVVRLEPVASAAPETLVTAVGPTVQRYLTGDLAEVFAG"
     gene            complement(17277..18032)
                     /locus_tag="KBX06_RS07730"
                     /old_locus_tag="KBX06_07730"
     CDS             complement(17277..18032)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014389.1"
                     /locus_tag="KBX06_RS07730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07730"
                     /product="ABC transporter permease"
                     /protein_id="WP_210833527.1"
                     /transl_table=11
                     /translation="MNPRILAATTGRILRQLRHDRRTVALLLVVPSALLVLVHSMYVDQ
                     PAPPGQPSTFDRVALVMLGFFPFVVMFLVTSIAMLRERTTGTLERLLTTPLGKLDLLFG
                     YGIAFGLAAVLQAVVASVVAYGFLGLDTAGHSGLVVMIASLNALLAVALGLFCSAFART
                     EFQAVQFMPVVVVPQLLLCGLFVPRGEMAGWLQAVSDVLPLSYAVEALQEVGAHAEPSG
                     TMWRDVAVVAGAAALALVLAAATLRRRSG"
     gene            complement(18029..18757)
                     /locus_tag="KBX06_RS07735"
                     /old_locus_tag="KBX06_07735"
     CDS             complement(18029..18757)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019868859.1"
                     /locus_tag="KBX06_RS07735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KBX06_07735"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_210833528.1"
                     /transl_table=11
                     /translation="MDEAIAVRDLVVERGGRRVLHGIRADVPRGSVTGLLGPSGSGKTT
                     LLRAVVGVQVVGAGSVTVLGRPAGSPELRRRVGYLTQAPSVYADLTVRENARYFAALHG
                     RGRAEADRAVAEVGLAPAAGQLAATLSGGQRSRASLACALVGEPELLVLDEPTVGQDPV
                     LRADLWARFHAMAAAGTTLLVSSHVMDEAARCDRLLLIREGRLIADDTPDAVRAAAGTH
                     DLDEAFLRLIRAGAGGQEAS"
     misc_feature    18978..18991
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.45"
                     /tool="antismash"
     gene            19064..>19660
                     /locus_tag="KBX06_RS27650"
                     /pseudo=""
     CDS             19064..>19660
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037778.5"
                     /locus_tag="KBX06_RS27650"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRGSHARRAATAHSDVDVDVLLAGAPYAARRAFLAEHGGRLTHV
                     SVAARDVRSWLARLGEPADWAFGLPVAAPARLLWADPHWRPRIDLPVLCQPAGEPQLEE
                     LIATLGKVAGARDADDHLGVRLAAADLARLCPSVLRLANPTVRVVSRRAAFAAALHLPV
                     APPNYREDLLLCLGLRPGSVGQLCAATARLVTGVLP"
     gene            19841..20278
                     /gene="hisI"
                     /locus_tag="KBX06_RS27655"
     CDS             19841..20278
                     /EC_number="3.5.4.19"
                     /GO_function="GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018223304.1"
                     /locus_tag="KBX06_RS27655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="WP_307854498.1"
                     /transl_table=11
                     /translation="MPVPDAPVTGAHPSPQESAADGAARPSRLDPTVAARLRRTPDGLV
                     AAVVRQHDSGEVLMVAWMDDEALHRTLTTGRATYWSRSRREYWVKGATSGHHQYVRAVA
                     LDCDGDALLVDVDQVGAACHTGHRTCFFTELPVGGGGAGAR"
ORIGIN
        1 gggtggtgac ggcatgagcc gcgtggcggt gctcgactac gggtcgggca acctgcgctc
       61 ggcggagcgg gccctggccc gggccggcgc ggacgtgacg gtgaccgacg acctggtcgc
      121 cgccgccgag gcggacgggc tggtggtgcc gggcgtgggc gcgttcgccg cctgcatggc
      181 cgggatcgag gcgctcggcg ccggcccggt gatcgccgag cgggtggccg ccggccggcc
      241 ggtgctgggc atctgcgtgg gcatgcaggt gctcttcgag cacggcgccg agcacggggt
      301 ggtgacgaag ggcctcgggc tgctgcccgg cggggtgacc aggctggccg ccgcccgact
      361 gccgcacatg ggctggaaca cggtcgcggc gccggcgggt tcggtgctct tcgccggcct
      421 gcccgccgac agccggttct acttcgtgca ctcgtacggg gtgggggacc cgggcgcgct
      481 ggcgggggcc ggcgccacgg tcaccaccgc ccaccacggg acggatttcg tggcggccgt
      541 ggagcggggc ccgctctgcg ccgcgcagtt ccacccggag aagtccgccg acaccggtgc
      601 cgcgctgctg cgcaactggc tggccacgct gtccaccggt ggctgagcgt cgccgcggtg
      661 cggtgggccc gctccgaccc gccgccggta gtgttcctgc gcgtcggcag tcacccggcc
      721 ggccgcgtcg ccgacggggc acgtcgtgag caaggagcgg gcccgccgcc gggcggcccg
      781 ggaggcgcag gccgcccggg aacgggtcgt gcgtgagcgc cggtcggccc ggcgctcacg
      841 tcgccgggcg ctggtccgcc ggttgacgcc gtcgctgcgc cgggggcgga cgggccggct
      901 gcctcggcac agccgtggcg aacgtgccgc catcgtgctg ctgacgctgg cggcgatggc
      961 gctgatctgg acgttcgtcg acgatctggc gctgcggatc gcgctggtcg tgctgttgct
     1021 gctcgtactg ccggcgatcg tggtgatcgc cctggaccgt cgcacctgaa ttcgaggaga
     1081 aacaccgtga gcctcaccct gttgcccgcc gtggacgtcg ccgacggcca ggccgtccgg
     1141 ctcgtgcagg gcgccgccgg cagcgagacg acgtacggcg acccgctgga ggccgcgctg
     1201 gcctggcagc gggacggcgc cgagtggatc cacctggtcg acctcgacgc cgcgttcggc
     1261 cggggctcca acgcgcacct gctggccgag gtggtgcggc agctcgacgt gaaggtggag
     1321 ctgtccggcg gcatccgcga cgacgagtcg ttgcacgccg cactcggcac gggcgcggcc
     1381 cgggtgaaca tcggcaccgc cgccctggag gaccccgtct ggtgcgaccg ggtgtgcggg
     1441 gagtacggcg accgggtggc gatcgggctg gacgtgcggg gtcgtaccct ctcggcccgg
     1501 ggctggacgc gcgacggcgg cgacctcttc gaggtgctgg agcggctgga caaggcgggt
     1561 gcgacgcgct acgtcgtcac cgacatcacc aaggacggca ccatgcgcgg gccgaacctg
     1621 gacctgctgc gcgaggtctg cgcccgcacc gacgccccgg tgatcgcctc cggcggggtc
     1681 tccacgctgg acgacctgcg ggcgctggcc acgctggagc cgctcggggt ggagggcgtg
     1741 atcgccggca aggcgctgta cgcgggcgcc ttcacggtgg cgcaggcgct ggagaccctg
     1801 gccgcggcgt gaccgtcacg cggctcggtt cgggcggccc gtgggagtcg ctgtacggct
     1861 actgccgggt ggtccgggcc ggcgacctgg ccgtgacggc gggctgcacc tccacggtgg
     1921 acggcacggt cacccacgtc ggtgacgcgg ctgcgcagac cgcccaggcg ctgcggatcg
     1981 ggctggacgc gctggccgag gtgggcgcgg agcccggcga cgtcgtgcgg acccggatgt
     2041 acgtgacgga ccggacgtac gccgacgagg tgggccgggc gcacaacgcg gtcttcggcg
     2101 cggtccgccc ggcggccacc atggtggtgg tggccggcct gctgcacccg gaccacctgg
     2161 tcgaggtgga gctggaggcc tatctcggcg accgctgaac cggtcggcgg tggcgtcggc
     2221 ggcggtggcg gcggtcgtgg tcgcgtcccg tcggggcggc ggtagcggcg gtcaccgccc
     2281 accccgatcg gttgtgcgca atacaattgc gcgctacggt ttcccggtga ccgaccatct
     2341 ggtgctgcgc cggcaggtgt gcttcgcgct ctacgccgcg tcgcgcgccc tcaccgacgt
     2401 ctaccggccc gtcctcgacg agttcggtct gacctacccg cagtacctgg tgctgctggt
     2461 gctctgggag cgcgacgacg cccccacggt ctccgagctc ggtgccgcgc tgcggctgga
     2521 ctccggcacg ctctccccgc tgctcaagcg gctggagggg gcggggctgg tcgtccggac
     2581 ccggtcggcg cgcgacgagc ggcgggtgga ggtgggcctg accggcgacg ggcgggccct
     2641 gcggcaccgg atggcggagg tgccgctgcg ggtcgcgctc gccacgggcc tcaccgaggc
     2701 ggagctggtc gccctgcgcg acaccctcac ccgggtcacc gagacgatcc accgacagaa
     2761 ggagcagtga ccatcatgca ggtgctctac accgcgtccg cccgggccac cggggacggt
     2821 cgggacggcc acgtccgcac ctccgacggc accgtcgacc tggatctggc cgtgccgaag
     2881 gagatgggtg gcgccggcgg cgccgccaac cccgagcagc tcttcgcggc cggctacgcc
     2941 gcctgcttcc actcggcgct gcgtctggtc gcccgcaagg ccaaggtcga cgtctcgggt
     3001 tcggtcgtcg aggccgaggt cggcatcggt gccaacggca gcggcggctt cgggctggcc
     3061 gtcaccctcc tggtggacct cccggccgcc gagcgggccg ccgccgagca ggtcgtcgag
     3121 caggcgcacc gagtctgccc ctactcgaac gcgacccgcg gcaacgtcga ggtggccctc
     3181 accgtacgcg aggcgctgtg agcacccgca accgcgagat ccacctcgcc tcccgcccgc
     3241 agggctggcc gacggccgac aacttccgcc tcgtcgagac cgacgtgccg acccccggcc
     3301 cgggtcagat cgtggtccgc aaccggtaca tgtcggttga cccgtacatg cggggccgga
     3361 tgaacgacgt caagtcgtac gtgccgccgt tcgcgctcga cgcgccgctg gacggcgggg
     3421 cggtcggcga ggtcgtggcc ggtgagaccg agggcctgcg gcccggcgac accgtgctgc
     3481 acggcctcgg ctggcgcgag tacgcgctgc tcgacgcgaa ggccgcccgg aaggtcgacc
     3541 ccgacctcgc cccggtcacc gcctacctgg gcgtgctggg catgaccggc ctgaccgcgt
     3601 acgccgggct gctggaggtc gccgggatga agccggggga gaccgtcttc gtctccgccg
     3661 ccgcaggcgc ggtgggcagc ctggtcggcc agatcgccaa gctcaggggc gcggcacgcg
     3721 tggtcggcag cgccggctcg gcggccaagg tcgaacggct gcgcgcgctc ggcttcgacg
     3781 ccgcgttcga ctaccacgac gggcccgtac gcgactcgct gaaggccgcc gcgcccgacg
     3841 gcgtcgacgt ctacttcgac aacgtcggcg gcgaccacct cgaggcggcg atctccgcga
     3901 tgagggtgca cggccgggcc gcgatctgcg gcatgatcgc gcagtacaac gacaccgagc
     3961 ccccggccgc gccgcgcaac ctggcgctgg tcatcggcaa gcggctcacc ctgcgcggct
     4021 tcctggtcgg cgaccacggc cacctgcgcg gcgagttcgt ccgcgagatg gccggctggc
     4081 tgcgcgacgg gaaggtctcc tacgacgaga cggtcgtcga cggcatcgag gacgccccgg
     4141 aggcgttcct cggcctgctg cgcggcgaga acctcggcaa gatgctcgtc cgggtgtgac
     4201 cggaagcgcc gctcctggcg ccacgggtcc cgctacgcgg tggccggcct caccggccgg
     4261 tcaccgccgg gaccgggaag gataggctcg cggcatgacg gtggcggtgc gggtcatccc
     4321 gtgtctcgac gtggacgccg gtcgggtggt caagggggtc aacttcctcg acctgcgcga
     4381 cgccggcgac ccggtggagc tggcggcggc gtacgaccgg gccggcgcgg acgagctgac
     4441 cttcctcgac gtcaccgcct cctccagcga ccggggcacg atgctcgacg tggtccgccg
     4501 cacggcggag tcggtcttca tcccgctcac cgtcggcggc ggcgtccggc aggtcgccga
     4561 cgtcgacacc ctgctgcgcg ccggcgcgga caaggtcggg gtgaacaccg ccgcgatcgc
     4621 ccgcccggag ctgatcgccg agatcgccga ccgcttcggc cggcaggtgc tggtgctctc
     4681 gctggacgta cggcgcgcgc ccggaggcgg cacgcccagc gggttcgagg tgaccaccca
     4741 cggcggccgg cgcggcaccg ggctcgacgc ggtcgggtgg gcccgccgcg gcgccgagct
     4801 gggtgcgggc gagatcctgc tgaactcgat ggacgccgac ggcaccaagg ccggcttcga
     4861 cctggaactc atcggcgcgg tgcgccgggt ggtcgacgtt ccggtggtgg ccagcggcgg
     4921 cgccggcgag gtggcgcact tcgcgccggc gatcggcgcc ggcgccgacg cggtgctcgc
     4981 cgccagcgtc ttccacttcg gcgagctgac cgtcgccgag gtcaaggacg cgctgcgcgg
     5041 ggccgggcac cccgtccgct gaccgcccgc gtgatctggc cggccggcgc aatccgcccg
     5101 gtccctccgg cccgcgtgat ccgcccggtc cctccggcct gcccggcccg tcggtgcccg
     5161 ctcagtcgcg gcgggaccgg ttctcgggcg aacgccgcgg cgccgggatc gaccgcacca
     5221 cgtactcctg gacggcggcg gcgtggtcgg cctcctccag ctgccactcc gcactgacgg
     5281 gggcgtgccg ccgcaccagc accccctgca cggtgtccac cgtggtggcc agcccggcgc
     5341 tcggccgggt gcgccagagg cgttcaccgt cggcggtgat ccggaaccag ccgtcggtga
     5401 cgctgaccag cccggccccg acgaggcgac ggaccgccgc ctccacctcg tgccgttcgg
     5461 ggatcgcctg gttgaggtgg tcggcggtgg agagcacgtc ggcgaggcgt acgccctcgg
     5521 ggcggcggct ggtcgccgcg cggcggtgcc gtcccgcacc gctggcgatc accaccgaga
     5581 cgaagatcca ggcatcgctc cagcgccatc cgttctcccc catgcgagga ttctgccggg
     5641 cgtggcgtcc gaagggaaca ccggcgtccg gcccgtgtcc ccgggacagg ggtgggctcg
     5701 gacgcggctc ggggtggcac tggggcggtg cgcccggccg ggtccgccgc catcccgggg
     5761 gcggcgcgcg ggtcaggccg tggggagcgg cgcgaccggg cccgcagtgg ggcggtcctt
     5821 cggcccggcg acggtgaaca gcggcaggaa gagctgggtc agcgggccga tggccagcgc
     5881 gtagacgacc gtgccgacgc ccaccgtgcc gcccagcagc cagcccagcg ccagcaccgc
     5941 gacctcgatg acggtgcgga cgagccggat cgagcggccg ggccggcggg cgacgtagcc
     6001 ggtcatcagg ccgtcgcggg ggccgggccc gaggcgggcg ccgatgtaga gccccgtcgc
     6061 cgccccgttg gccacgatgc cggcgaccag catcccggcc cgtacgccca gcggcccgcc
     6121 gcccggcagc agcgcgagcg ccgcgtccac caccagcccg atcaccagga cgttgctgac
     6181 cgtgccgagg ccggggcgct ggcgcagggg tatccagagc agcagcacca gcgcgcccac
     6241 cgcgatggtg acgatgccga aggagaggcc ggtcagctcg gacaggccct ggtggaacac
     6301 gtcccacggg tcgagcccca gccccgattc gatcatcagg gccatgctca cgccgtagag
     6361 gacgaggccc gcgtagagct ggctgagccg ccgcacggaa cgatgtcgga gattgccaat
     6421 cggtgtcacc catgccacgc taaaggccaa ttagcgcagc gtaagagcca atccggggag
     6481 agtggccatg acgagtcagg ttaggggtgc gcaattggcc cggctcctcg gccagtggca
     6541 tgcccttccc ggccgccgcc gcagccccga ctacgccgcc ctggccggtg ccgtacgcgg
     6601 gctgctcgcc gacggccggc tgccgctggg cgtgcggctg cccgccgagc gggagctggc
     6661 cgaggcgctg aagatcagcc ggaccacggt cacggccgcg taccgggagc tgcgggagag
     6721 cgggcacctc gccagccggc ggggggccgg cagctggacg atgctcccgg gcacccaccg
     6781 ggtggcgagc accgggctct ggaccccgct ggacgaccgc gacatgatcg acctcggggt
     6841 cgccgcgctc gccgcaccgc ccgagctgct gccggccgcc cgcgcggcgg ccgaggacct
     6901 gccccgttac ctgggcggcg ccggctacca cccgaccggc atcatcgagc tgcgcgaggc
     6961 ggtcgcccgc gcctacaccg cccggggcct gcccacctcg cccgaccaga tcatggtcac
     7021 caacggcacc cagcacgccc tcgacctggt gctccggctg gccctggccc ccggcggcaa
     7081 cgtgctggtc gaggcgccca gctatccgaa cgcgctggcc gcgctggccg cccgccgggc
     7141 ccggatcacc acccacggtc tggccgtcga ggagcccgga tgggacgccg acctgctgct
     7201 cggcggcctc cggcaggcgc ggcccaagct ggcgtacctg atcccggact tccagaaccc
     7261 gaccggccac ctgatgccgg cggcgctgcg ggaacgggtg gtggccacgg cgcacgccgt
     7321 cggcaccgac ctggtcgtcg acgagtcctt cgtggacctg ccgctggacg ggaccgtgct
     7381 gcccccgccg accgccagct tcgaccggca ctcccgggtc atcaccatcg gcgggatgag
     7441 caagcccttc tggggcggcc tgcgcatcgg ctgggtccgg gcctccgccc cgcaggtgca
     7501 gcggctcgcc gccgcccgcg tcggcgtcga catggccagc cccgtcctgg accagctggt
     7561 cgcggtgcac ctgctcgccg acgcgccggc catcgtcgcc gcccgccagg cccagctgac
     7621 cgctcagcgc gacgcgctgc tcgccgcgct cgcgcagcgc ctgcccgagt ggcgggtcac
     7681 cgtcccgcac ggcggggtga cgctctgggc cgagctcgac ggcccgatct ccagcgcgct
     7741 ggcccgggcc gccgaggagg tcggcgtacg cctggcaccc ggcccccggt tcggcctgga
     7801 cggcacgttg gaacgcttcc tgcgactgcc gttcaccctc ccggccgccg acctggtcga
     7861 ggcggtcggg cgcatcgcgg cggtccgcta cgacctggac cggggcggtc ggtcgcagtg
     7921 gcgggagccg acggtcatcg cctgaggggg gccggcgttc gctgcccgcc cccggccctg
     7981 ccccggacgc cggtgacccc gcgccgcagc gcggggtcac cggcgtcgca tgctcagagt
     8041 tcggccagcg agcccgcgta catcttctcg atctcgccgg cgaagttgct ctccacgccg
     8101 cggcgcttga tcttcaggga cggggtgatc tccccgtcct cgatggtcag gtcgcgcggc
     8161 aggatggcga ccttcttgat cgtctcccag cggttgagct tcgcgttgag ctcggccacg
     8221 taaccctcga ccatggcctt cgcctccggc gaggagacga tctcggtgta gtcgcggccc
     8281 tccaacgggg tgccgacggc ccagcccttg atcgcctcag ggtccagcgt gaccagcatc
     8341 gtgcagtagt tgcgggcctg gccgatcacc accgcctggg aggtgtacgg gcaggtcgcc
     8401 ttgaacagcc cctcgatgtg cgaaggcgcg acgtacttgc cgcccgaggt cttgaccagg
     8461 tccttcttcc ggtcggtgat cttcaggtag ccgtcggcgt ccagggtgcc gatgtcgccg
     8521 gtgcggaaga agccgtcctc ggtgaacgcg gccgcggtct cctcgggcag gttgtggtag
     8581 ccgcgcatca ccggccggcc gcgcaccagg atctctccgt cggtgtcgat ccggcactcc
     8641 aggtcgccca tcgccttgcc gacggtgccg atccgcagcc cgtccggcgg gttgacgaag
     8701 ttgccggcgc tggtctcggt gaggccgtag ccctcggaga tcggcaggtt cgccgcggcg
     8761 aagaaggtgg cgatctccgg gctgagcggg gcggcgccgg agacgaggac ccggatccgg
     8821 cccccgaggc gggcctggag cttgctgaac accagcttct cggccaccgt gtacttcagc
     8881 ttcagccccg tcgggacggg cctgccggcc tgctccaggg cgaccttctc ggtaccgacc
     8941 cggacacccc aggcgaagat cttcgccttc gcgccgccgc tggcctgcgc ggtggtcacc
     9001 gccttgttgt agaccttctc gtagacccgg ggcgcgccgc acatcagcgt cgggcggatc
     9061 accgagagca gctcgaccag cttgtcgacc cggccgtcga cgtacgtcgg caggcccacg
     9121 tggatcgccc cgcagagcag ggtcttgccg aacgagtgcg acagcggcag ccagaggtac
     9181 tgcaggtcgt tctcgcggag cagccccagc tcggcctgcg ccacgccctc ccagcaccag
     9241 ccgccgtgca gcagctcgac gcccttcggg cggccggtgg tgccggaggt gtagatcagg
     9301 gtggccaggt ggtcggggcc gatcccggcg accagcgtgt cgatcaggtc gggctgggcg
     9361 gcaagggcgc gggcgccctg ctcctccaac tcggcgaggg tgagctgggg gacggcggcg
     9421 gccgggtcgg cggcgccgtc gaagagcacg acgtgggtca gcgccggcag gtcggcgccg
     9481 gcgatcttgg cggcctgggc cgggtcctcg gcgaacagca cgcgggagcc ggagtcggcg
     9541 acgatgtagg tcgcgtcgtc gggctccgtg gtcgggtaga cggtggtggt cgcgccaccg
     9601 gcgcacatga tgccgaggtc ggcgatcacc cattcgagcc gggtgttcgc caggatcgcg
     9661 accggatcct ccaggccgac accgaggccg tgcagcccgg cggcgaccgc cttggcgcga
     9721 cgggccatct gctcccagtt cagccagacc gggccggagt cgtcgggggc cgggtgggcg
     9781 aaagcgtcac ggtcggggga cgccgccacg cgcttgagga acatgtcggg gatggaacgg
     9841 tacggtacat cgagagccat cgctgtagcc gccttcgggg ggtggagacg tgacagcggt
     9901 cacgtcggcg ttcgttaccg aagggtattg cctgcgcccg gccatcggct agccctgtcg
     9961 atcacggctg ggccacggct cggcagatgg aacgcccggc tcaggcgtac cgggccgccc
    10021 gcagcgacca gtcgtaggtg gcgcggatcc agttgcgccg ggcggtgagg gcggtccgca
    10081 gaccgtcgtc gccgacggtg agcagtgccg tctccgtcgc caggtaggtc gacagggcct
    10141 cgttgaaccg gtcggccgcc gcccgcagcg ccgccgactc gtcgccgtcc gtccgccccg
    10201 cggcgagcac cgcgaccagg ttgtgcgcgt ccggccggct gaggtgctcc ttgccgtacg
    10261 agaagacgtc gttgcaccag cagaccaggt cggcggcgag caggtcgagg gcgaccagcg
    10321 acggctcggt gcggtgggcc gcgcccggcg gagtcccgcc ggccagttcg gtcagggtga
    10381 agctggggtg gaccgcgccg gtgtgccggc gcatctgggc gtactcggcc agccccggca
    10441 cgcgcccgtg ctcccggttg gccgcctccc acagcagcgc cagcagatac tcccgcacct
    10501 ccccggcgaa gcgcagcagc gccgtcggcc cgccggcggc gcgggcccgc cggcacaggt
    10561 cgccgagcgc ctcgccgagc ggcccggccg cggtcaccgg cccgtcggcc cgaccgccct
    10621 gcccgtcgag cacgtccagc agggcggcga cggtcggtgc cagccgggtg ggggaggcgc
    10681 cgaggccgtc ctcgtcgcag gcgtcgtcca tcacgaacag ccaggagatc aggtcggcga
    10741 gcagccgcaa cccgtcgacc gggccgtccg ggtaggcccg cccggccagt ccggcggcgt
    10801 cggcccggtg tagtcggtgc agcccgtgcc cgttactgat cagtccgtgg ccgagcgccc
    10861 actccgtgct ctcccgcgcc acccgctcgg tggcgtcgtg ttggcgctcg ggaaaggggg
    10921 gttcccgtag cgccgagacc gcaaaggtcc gcatggtgcc ccctgtcgcg ctgtcccacc
    10981 cgggatcgcg cgggacagcg tacgggagca gggatcggtc gcgatcgttg gggaggcgcc
    11041 tgctcacgct gcgctgtgac cgtttgcgtg cagtgcgtca catgcccagg tcggtgcccc
    11101 gcagccggtc ggccagcgcc gccggcccgt cgatctgcat ccgggacacc cgctgccggc
    11161 cgctgaggaa cagggccagc tcgcccggcg caccggccac ccgtacggaa tcgccgcccc
    11221 ggcccacgtg cagctcgccg tagccgggag cctggacgag gacgtcggcc gggaaccggc
    11281 gcagcgccag ccgggccagc ccggcgcacc gcttccacag cgccgcgttc agccctgccg
    11341 ccaggtcgcg tgggagccag tcggggcggg cgcggcgcac gtcctcgtgg tggatgaaga
    11401 actccagcgt gttggccagc tcgtcggtga ccgggttgct gaccgggctc cacgccggcg
    11461 gccggcgtac ctcgtcgaga aggcgcggcc aggcgcgcgc ggcgatgcgc aggcgcaccc
    11521 gctcggcgtg gccgcgcagc ggcggaagca cgatgccgcc ggcggcgtcg ggccggcgtt
    11581 cccggagcac caggtgggcg gcgaggtcgc ggatggtcca cccgtcgttg accgtgggcg
    11641 cctccggtcc cagcgtctgc atcaggtcgg cgagcgcctc gcgctccgct cgggcgtacc
    11701 gcggcatgac accgatcgta ggcgcggacg agccgatcgg cgcgccgagc gggccggggc
    11761 cgtcgtgacg gtggacatag cggtccgggg cggcggagcc ggccccgaac ggtaaggatg
    11821 aggaggataa ttgcggctta cggcagggga gagcgtggcg agcaggacaa gtcgggacgt
    11881 gctggtgcga gggctggccg tcctcgggcg ggcgatccgg gaggagccgc gcatcttcgc
    11941 ggtcgcggtg agcagcagcg tgctcttcgg cgccatgacg gtggccagcg ccttcgtggt
    12001 cggtgccgtg gtcggcgacg tggtggtgcc cgcgatcgag cgcggcgcgg tcggggtcgg
    12061 tgggctcgcc ctggccgccg tcgcgctgtt cggcatcagc gtgctgcggg tggccggcat
    12121 cttcggccgc cggctcggcg cgggctacat gcagtaccgc ctccaggccg cctaccggcg
    12181 ccgggtcacc cgccgctacc tggagctgcc gctggcctgg caccaccgca acgccaccgg
    12241 cacgttgctg tccaacgcca actccgacgt cgaggccgcc tggtacccga tcgccccgct
    12301 gccgttcgcg gtcggcaccc tggtgatgct ggtcggcgcg gtggcgtcgc tcttcgtcac
    12361 ggactgggcg ctggccctgg tcggcctcgc ggtcttcccg gcgctcttcg cgctcaacgt
    12421 cgcctactcc cgccggatgg ccccccggca ggcccgggcc cagcggctgc gcgccgaggt
    12481 cagcggcatc gcgcacgaga gcttcgacgg cgccctggtc gtcaagacga tgggccggga
    12541 ggcgcaggag accgaccggt tcgccgcccg cgcgggtgag ctgcgcgact cgctggtggc
    12601 ggtcgggcgg ctgcgcggcg tgttcgaccc gctgctggag accctgccca gcctcggtac
    12661 cctcgccgtg ctggtggtcg gcacgatccg gctgcggcag ggcgcgatca ccgtcgccga
    12721 gctgatcagc gtcgccttcc tcttcacggt gctggcgttc cccgtgcgtg ccatcggctg
    12781 ggtgctggcc gagctgccgc gcagcgtcgc cggctgggac cgggtcagcc gggtgctcga
    12841 cgccaccggc aggatgccgt acggcgacac gacgctcgac gtgtcggagc cccggccggc
    12901 gagcctcacg ttcaccggcg tgcgtttcgg ctacgagccg gccgaggcgc acctgcccgg
    12961 cacggaggtg ctcggcgagg tctccttcac cgtgccggcc gggaagaccg tcgccctggt
    13021 cgggccgacc ggctccggca agtcgacgat cgccgcgctc gccgtgcggc tggtcgatcc
    13081 cctggccggc accgtgtgcc tggattcggt cgacgtccgc cggctcaccg ccgcctcgct
    13141 gacgggcacg gccgcgctgg tcgcccaggt gccgttcgtc ttcgacgaca cggtgcgcgc
    13201 caacgtcgcc ctggaccggg cgggcatcgg cgacgacgac gtctgggccg cgctgcggct
    13261 ggccgaggcg gacggcttcg tcgcggccct gcccgacggc ctcgacacga tggtcggcga
    13321 gcggggcacc tcgctctccg gcggtcagcg gcagcggctc accctggccc gcgcgctcgc
    13381 cggtcggcca cgcctgctgg tcctcgacga cgcgaccagt gcggtcgacc cccgggtcga
    13441 ggcggccatc ctggccgggc tgcgctcgtc ggcggccggg gcaccggccg cgtcgatcct
    13501 ggtggtcgcc taccggcggg ccaccatcgc gctggcagac gaggtggtct acctggaaca
    13561 gggccgggtg ctcgcccgcg gccggcacac cgagctgctg gccacggtgc cgggctacgc
    13621 cgacctggtc accgcctacg agcaggccga ggtcgacccc gccaaggacg agacgtacga
    13681 cgaggttgcc ccggtgacgt cgggcctgaa gatcgaggtg gaccggtgag cgcgaggagt
    13741 gcagcgcagc ggagccccgc agtcgcgaac gaagggtggc tgcggtgagc gcgaggagtg
    13801 cagcgcagcg gagccccgca gtcgcgaacg aagggcgggc ccggtgacca ccaccaccga
    13861 cacggcacgg aagaccgcga ccgtcgagac ggccgaggca cctgagccac ccgagacgac
    13921 ctggcagacg atgcgccgcg gtctggcgct ctccccggag ctgcgggtcg gcctggccgg
    13981 cacgctcggc ctggccctgg tctacatggt cggccgggcg gccgtgccgg tggcggtgca
    14041 gcagggcatc gacaacggca tcgtcgacgg cctggacctg ggcgtcatct ggacggtggt
    14101 cgccgtcacc gccgcggtgc tggtggtgac cacgctctgc gggtacctga tgatgcgccg
    14161 gctcttcacg gtcagcgaga ccgcgttggc caacgtgcgg atccgggcgt tccggcacgt
    14221 gcacgacctg tccatgctgc accagcagtc ggagcggcgc ggttcgctgg tctcccgggt
    14281 gaccagcgac gtcgaccaga tcacccagtt cctccagtgg ggcggcgtga tcctggtgat
    14341 caatctcggt cagctggcgg tcaccacgct ggtcatgttc gcgtactcct ggcagctgac
    14401 cctggtggtc ttcgccgcct tcctgcccgc cgtgttcgtg atccggcggc tccagcgccg
    14461 cctcgccggg gcgtacgggg tggtccggca gcgcacgggg gcgctgctcg gcgcgatcgg
    14521 ggagagcgtg gtcggtgcgc cggtgatcag ggcgtacggg atctccggcc ggacggcccg
    14581 ccggctggac gaggcgatcg acggccagcg ccgggcccag cagcgggcga tcaggatcag
    14641 cgtcatgggc agctcggtcg gcgagctggc cgccgggctg gcgttggccg gcgtggtggt
    14701 gctcggggtg accctcggcg ccgaccgcac cctgagcatc ggcgaggtga ccgccttcct
    14761 cttcctggtc acgctcttca tccagccggt gcagatcgcc accgaggtgc tcaacgaggc
    14821 gcagaacgcc atcgcgggct ggcgtcgggt gttggacgtg ctggacgtcg agcccgacgt
    14881 cgccgatccg ggcgagcagg ggcgcgaact gccggccggc ccgctggaca tccgcttcgc
    14941 gggggtgcgt ttcgcgtatc cggggggtcc gcccgtgctg cacgacgtca gcctggagat
    15001 tccggcgaag agccgggtgg cggtggtggg ggagaccggc agcggcaaga ccaccttcgc
    15061 caagctgctc acccgcctga tggatccgac cgcaggccag gtgctgctct ccggtgtgcc
    15121 gctggagcgg gtccggttcg cctcgctgcg gtcgcgggtg gtgatggtgc cgcaggacgg
    15181 cttcctcttc gacgccacgg tggcggagaa cgtccgcttc gcccgcccgg agctgaccga
    15241 cgagcagctc gcggcggcct tcaccgagct ggggctggcc gactggctgg acgcgctccc
    15301 gtcgggtctg cacacctgcg tgggggagcg cggcgaggcg ctgagcgtgg gggagcggca
    15361 gcttgtcgcg ctggcccgcg cgtacgtcgc cgacccggat ctgctggtgc tggacgaggc
    15421 gaccagcgcg gtcgacccgg ccacggaggt gcggctgcaa cgcaccctgg acgcggtgac
    15481 ccgggggcgc accaccctcg cgatcgcgca ccggctctcc acggcgcagg ccgccgacga
    15541 ggtgatcgtg gtggaccggg gccggatcgt gcagcgcggt ccgcacgacg agctggtccg
    15601 cgacccggag tcggtctacg gcctgctcta cgcctcctgg ctggagcaga cccgctgagc
    15661 ggacgagtcg cgcagcaacg tcatccgcag ttccggcacg ctggacgtca ccgttccggt
    15721 gctctagtct ccgagttagg taaggctaac ctacgaagga gcggttcatg cggcccagcc
    15781 cggcagagat cgtccgtacc ctcgtcgcgg gccggctgcc cggcatcgcc cacgtcgcgc
    15841 accggcccgg cccgcatcag gtccggcacg tgaccgaccc ggacggtcgg gtgctgctgc
    15901 tggtgccggt ggtcagcgac ctcgccgccg cgctgcgtcc cgccgccggc gaagccgcgg
    15961 tcgcgctcgt gctggacgtg ctggacctgc cgcccgccgc cggtgcgccg agcctcggcc
    16021 gggcctgggt ctccggctgg gcggcccgcc tggcggggga cgaggagcgc cgcgccgcgc
    16081 tggacttcgc cgacgtcgag ccggccggtg acctgctcga cgtcggcacc cggttccggc
    16141 tgcaccgctt cgaggtggtc gaggcccgct gggaacgcgg cgacaccgtc cgccgcgtcg
    16201 acccggaggc gtacgccgag gcggagcccg acccgctgca cgcggtcgag gcagagctgc
    16261 tggccgacct cgccggccac cacgccgccg aggtggccgg ctacctgggc cgccagctcg
    16321 gcctcgccga cgacgccccc gacgccgcgc cccgggtggt ccggatcgac cggtacggcc
    16381 tgctggtcac ccacggccgg cccggcgccc ggcggcgcgt ccggttggcg ttcccccgtc
    16441 cgctggactg ccgggcggag ctgacccggc tgctgcaccc actggtcggc cggcacgcct
    16501 cgccccggca cgccgaccac gcctgaccgg cgggcaccgg ccacggccgc ccggtcagcc
    16561 ggcgaagacc tcggcgaggt cgcccgtcag gtagcgctgc accgtgggcc cgaccgccgt
    16621 gacgagcgtc tccggggcgg ccgaggcgac cggctccagc cggaccacgt accgcatcac
    16681 ggccagcccg atcatctggc tggccaccag ggagccgcgc agcggcagct cggccggatc
    16741 gacgtcgagc tggtcgagga ccctgcgcag cacctgggtg accaggaact cgcgcagcag
    16801 ccgggcggtc cactcgttgc tcaccgccga gcgcagcagg gccaccccgg cggtgccggc
    16861 cggggagtcc cagacgccga ggaaggtgcg taccaaccgc tccccgagac ccgcccggtc
    16921 gcccgccagc acgctcggca gcagctcggc ggggtcgacc ggcgcgtgca tcgcggccag
    16981 gaagaggcgg tccttgctgc cgaagtagtg gtgcaccagc gccgggtcga cctgcgcggc
    17041 ggcggcgacg gcccggatcg aggccccgtc gaagccccgc tcggcgaagg cggcgcgggc
    17101 cgcgtcgagg atggcctgcc gggtgtccgg gttcccgggg cgtcgtccgg tccgccgcgc
    17161 catcgccacc cttcgcttga ttgtcggttc cgccgtcgga ccggcttggc cgtcggtgcg
    17221 ccagccggcg gggtgccgcg cggcaccggg gccgtcctgc cggccgggcc ggcggctcag
    17281 ccgctgcgcc gccggagggt ggccgcggcg agcaccagtg ccagcgccgc cgcgccggcg
    17341 accaccgcca cgtcccgcca catcgtgccg ctcggctcgg cgtgggcgcc gacctcctgg
    17401 agcgcctcga cggcgtacga caggggcagc acgtcgctga ccgcctgcaa ccagccggcc
    17461 atctcgccgc gcggcacgaa gagcccgcag agcagcaact gaggcaccac cacgaccggc
    17521 atgaactgta cggcctggaa ctcggtgcgc gcgaaggcgc tgcagaacag cccgagcgcg
    17581 acggcgagca gagcgttcaa cgaggcgatc atgaccacca ggccgctgtg gccggcggtg
    17641 tccagcccga ggaacccgta cgcgaccacg gacgcgacga ccgcctggag caccgcggcg
    17701 agcccgaacg cgatgccgta gccgaagagc aggtcgagct tgcccagcgg cgtggtgagc
    17761 agccgttcga gggtgcccgt ggtgcgctcg cgcagcatcg cgatgctggt caccaggaac
    17821 atgaccacga aggggaagaa gccgagcatc accagggcga cgcgatcgaa cgtcgacggc
    17881 tgtcccggcg gggcgggctg gtcgacgtac atggagtgga ccaggacgag cagcgccgac
    17941 gggaccacca gcagcagcgc cacggtgcgc cggtcgtgcc gcagttggcg caggatgcgg
    18001 ccggtggtgg cggccaggat ccgggggttc acgacgcctc ctgcccgccg gcgcccgccc
    18061 tgatcagccg caggaacgcc tcgtccagat cgtgcgtgcc ggcggcggcg cgcacggcgt
    18121 cgggggtgtc gtcggcgatc agccgcccct cgcggatcag cagcaaccgg tcgcagcggg
    18181 ccgcctcgtc catgacgtgg ctggagacca gcagcgtggt gccggctgcg gccatggcgt
    18241 ggaaccgggc ccacaggtcg gcccgcagca ccgggtcctg accgacggtc ggctcgtcga
    18301 ggacgagcag ttccggttcg ccgaccaggg cgcaggccag cgacgcccgg ctgcgctgcc
    18361 cgccggagag ggtggcggcc agttggccgg cggccggtgc gagcccgacc tcggcgacgg
    18421 cccggtcggc ctcggcccgg ccccggccgt gcagggcggc gaagtagcgc gcgttctccc
    18481 gcaccgtcag gtcggcgtag acgctgggcg cctgggtgag gtagccgacg cggcggcgca
    18541 actccggcga cccggcgggg cgccccagca cggtcaccga gccggcgccg accacctgca
    18601 cgccgaccac cgcccgcagc agtgtggtct tgccgctgcc gctcgggccg agcagcccgg
    18661 tgaccgaacc gcgcggcacg tccgcgcgga tgccgtgcag cacccgccgc ccgccccgct
    18721 cgacgaccag gtcgcgtacg gctatcgcct cgtccaccgg cgcctcccgg gaaaattcat
    18781 catccgttga actcgacgct aacggagacc ccgccgggcc gcaacggtcg gccccggtcc
    18841 acccgtgcgg accccggagc ggcggggaga tcggtcgggc attagccttc ggaccggaca
    18901 gcgggtccgc caacgggcat ccgtcgcggc agcgggcatt gcgccctgat cggacgtacg
    18961 gcacgatggc gccgtgggtc acgctgtgtc accggacgaa ggcttcctcg gcgagtgggc
    19021 gacccggtta cgggccggtg ccgagcagcc cgtggtgggc atcatgctgc gtggcagcca
    19081 cgcccggcgg gccgccaccg cgcacagcga cgtcgacgtc gacgtgctgc tcgccggtgc
    19141 cccgtacgcc gcccgccggg ccttcctggc cgagcacggg ggccggctga cccacgtctc
    19201 ggtggccgcc cgcgacgtgc gctcctggct ggcccgcctc ggcgagcccg ccgactgggc
    19261 gttcgggctg ccggtggcgg cgccggcccg gctgctctgg gcggacccgc actggcggcc
    19321 ccggatcgac ctgccggtgc tctgccagcc cgccggcgaa ccgcagttgg aggagctgat
    19381 cgcgacgctc ggtaaggtcg ccggggcgcg ggacgccgac gaccacctcg gcgtccggct
    19441 ggccgccgcc gacctggccc ggctctgccc gtcggtgctg cggctggcca accccacggt
    19501 ccgggtggtg tcccggcggg ccgccttcgc cgccgccctc cacctgccgg tggcaccccc
    19561 gaactaccgg gaggacctgc tgctctgcct cggcctgcgg cccggctccg tcggtcagct
    19621 ctgcgccgcc acggcccgcc tggtcaccgg cgtgctgccg ctgatccgcc cgtacgccgc
    19681 cgaggtcgcg cgggtcgccg gcgcggacct ggccgacgcc ctgagcgacg gccggctgga
    19741 ccgctacgtc gaccagctga cccggcccgc ccgccgacca ccgcggcccc ggcgggagcc
    19801 gtcgcccgtg cccgccccgc gtgcgggaca atgggtcact gtgcccgtac ctgacgcgcc
    19861 cgtgaccggc gcccacccca gtccgcagga gtccgcggcc gacggcgcgg cccgtccgtc
    19921 ccggctcgac ccgaccgtcg ccgcccggct gcgccgcacc cccgacggtc tggtggccgc
    19981 cgtggtccgc cagcacgact ccggcgaggt gctgatggtc gcctggatgg acgacgaggc
    20041 gctgcaccgc accctgacca ccggccgggc cacctactgg tcgcgcagcc gccgcgagta
    20101 ctgggtcaag ggcgccacgt ccgggcacca ccagtacgtc cgcgcggtgg cgctggactg
    20161 cgacggtgac gcgctgctgg tcgacgtcga ccaggtcggc gcggcctgcc acacggggca
    20221 ccgcacctgc ttcttcaccg agctgccggt cggcgggggc ggggcggggg cccggtgacg
    20281 acccagcgcg cgacgcccgg cggcgggtcc cgcaccgacg gcgcggtcag ccccgacctg
    20341 gccaccttca cggggctggc cgcccgctgg cgggtggtcc cggtcacccg ccggctgctg
    20401 gccgacgcgg agacccccgt cggcgtctac cgcaagctcg ccggtggccc ggggacgttc
    20461 ctgctggagt ccgccgagca gggcgtcggc tcggccggcc tggcctggtc gcgctactcg
    20521 ttcatcggcg tacgcagcag cgccacgctg accgagcggg acggcgccgc ggtgtggacg
    20581 ggacgccccc cggccggcct gcccacctcc ggcgacccgg tccgggtgct gcgcgagacc
    20641 gtcgaggcgc tcgccggccc ggcctgggac gcggccagcg gcatgccgcc gctgaccggg
    20701 ggcatggtcg gctacctggg ctacgagctg atccggcgct tcgagcggct gcccgagctg
    20761 accgaggacg acctgggcgt gcccgagctg ggcatgatgc tcgccgtcga cctggtggtc
    20821 ctggaccact acgacggatc ggcgatcctc gtcgccaacg cgatcctgcc gccgtcgacc
    20881 gagccggacc acgacgtcca ggtcgcggcg gcctaccacc acgcggtcgg gcggctcgac
    20941 gcgatgacca ccgc
//
