LOCUS       NZ_CP072827            25167 bp    DNA     linear   CON 18-JAN-2024
DEFINITION  Streptomyces mobaraensis NBRC 13819 = DSM 40847 chromosome, complete
            genome.
ACCESSION   NZ_CP072827
VERSION     NZ_CP072827.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces mobaraensis NBRC 13819 = DSM 40847
  ORGANISM  Streptomyces mobaraensis NBRC 13819 = DSM 40847
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7574085)
  AUTHORS   Li,P.
  TITLE     Telomere system of Streptomyces mobaraensis DSM40847 linear
            chromosome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7574085)
  AUTHORS   Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2021) Institution of Microbiology, Jiangxi Academy
            of Science, Changdong Road 7777, Nanchang 330012, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly         :: AORZ00000000
            Genome Coverage                   :: 60.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/18/2024 06:31:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,545
            CDSs (total)                      :: 6,448
            Genes (coding)                    :: 6,310
            CDSs (with protein)               :: 6,310
            Genes (RNA)                       :: 97
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 23 of 138
            Pseudo Genes (incomplete)         :: 120 of 138
            Pseudo Genes (internal stop)      :: 5 of 138
            Pseudo Genes (multiple problems)  :: 9 of 138
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:35:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6789055
            Orig. end                         :: 6814222
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072827.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25167
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="31"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25167
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25167
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15167](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15167
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            245..943
                     /gene="thyX"
                     /locus_tag="J7W19_RS29300"
                     /old_locus_tag="J7W19_29300"
     CDS             245..943
                     /EC_number="2.1.1.148"
                     /GO_function="GO:0050797 - thymidylate synthase (FAD)
                     activity [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="thyX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017235841.1"
                     /locus_tag="J7W19_RS29300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29300"
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="WP_004938032.1"
                     /transl_table=11
                     /translation="MTEIEFRSDMDVELVDSMGGDHSIVRAARVSSGTEAGDPAKDKGL
                     INFLARDRHGSPFEATVFQFKVTVPLFVAREWFRHRIGSFNEVSGRYKEMEPVFYVPDE
                     GRPLKQIGTPGKYTFEAGSITQGRHTRTAHRQAAQTAWDAYQEQLALGVAREVARNVLP
                     LSLYTSFYWTVNGRSLLNFLSLRRVTADTTVPTFPLWEIDRAAGQVEELAQQVTPEAFA
                     AFNKHGRVTP"
     gene            1017..1256
                     /locus_tag="J7W19_RS29305"
                     /old_locus_tag="J7W19_29305"
     CDS             1017..1256
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29305"
                     /product="hypothetical protein"
                     /protein_id="WP_004938027.1"
                     /transl_table=11
                     /translation="MIKFYYLPDCAPCEATKPRAIQAAQQAGKDILFINAQTRAPEDLH
                     AEGVTIAPTISNGVRSIKGEQTFERLVRFFEEAN"
     gene            1351..1647
                     /locus_tag="J7W19_RS29310"
                     /old_locus_tag="J7W19_29310"
     CDS             1351..1647
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29310"
                     /product="hypothetical protein"
                     /protein_id="WP_004938023.1"
                     /transl_table=11
                     /translation="MSFNNVIPGWVAARMAEITTERTLLHQGAVAGPREDPDGNPTVLL
                     TGTYYEERCERTGKVTSSHSNTLHLTFEAAVLLRAHLDEAIKTHRIYKEFKRA"
     gene            1640..1879
                     /locus_tag="J7W19_RS29315"
                     /old_locus_tag="J7W19_29315"
     CDS             1640..1879
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29315"
                     /product="hypothetical protein"
                     /protein_id="WP_004938019.1"
                     /transl_table=11
                     /translation="MPDYGAMPDPDEFAQYLKDSGFNTLDAQMNEATETIAKVITKGAE
                     LKKHAQANGFSEAVAEEIGFVFIERLISNEGGSK"
     gene            1876..2052
                     /locus_tag="J7W19_RS29320"
                     /old_locus_tag="J7W19_29320"
     CDS             1876..2052
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29320"
                     /product="hypothetical protein"
                     /protein_id="WP_158688705.1"
                     /transl_table=11
                     /translation="MTDALIFVEYPDSSVDEFTGEVVYERDCVLIYEEGGTSHRINHHH
                     TRAVHVHPISQEV"
     gene            2055..2264
                     /locus_tag="J7W19_RS29325"
                     /old_locus_tag="J7W19_29325"
     CDS             2055..2264
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29325"
                     /product="hypothetical protein"
                     /protein_id="WP_004938017.1"
                     /transl_table=11
                     /translation="MFVLKSRLVAAMRLMVEQEKELEFRADAYLKLLQKNAELETNYSK
                     LEGEIRELKLSLPARDAQGRFSKR"
     gene            2337..4256
                     /locus_tag="J7W19_RS29330"
                     /old_locus_tag="J7W19_29330"
     CDS             2337..4256
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012688.4"
                     /locus_tag="J7W19_RS29330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29330"
                     /product="DNA polymerase"
                     /protein_id="WP_078587589.1"
                     /transl_table=11
                     /translation="MIRMCVKIAGAPVVINVLEDSGDIPEFVEWVRRNRSALGCDTETT
                     GLDWWADDFRLRLVQFGNHDESYVLPVELSDELLGAAVGAIRFVNKLIFQNGSYDLLVL
                     DATTDLTMEEIWPKVLDTKILAHLVDSRGEADAGIGHSLASLTKHYIDDGVAAKIKGSM
                     AEIARSLKTTKARVWKLVAWNHGGYLTYSGLDPILAFRLGRILIPKLPRTVYRKTDIGP
                     GIPPMNLIEFEHKVAEICALMSRPGIALNRDYALRLEARLALEEHRWTARAQELGCENP
                     WSTEQCADAFEARGITVFDTTPTGNRKVDKVFLADWRARGDELAEAIYQAKAARKKRNT
                     WLRSFLESVDSNGRIHPSINSIQARTARQSIQGIPAQTLPSGDYEIRACFEANEGHIVL
                     STDYSNMELRFLAAHSGDKRMLRAFRNGEDLHQVTATAAGVSRKLGKMTNFLIVFGGGP
                     EALSSQAGIPVHEAKRIMDIFMETYPGVEAFMKLKTQEARRQGYVTTPSGRRLYVEKKF
                     AFRGTNYFVQSGSRDITCRALVRLHHAHLAQFALLPIHDEILFSVPIEHADTAAKMTDE
                     LMKETVLGLEIPTDPDRGGKSWGSLYMKGVENLTKLDDYYRDNPEQALADDRRRNPDDH
                     AAAA"
     gene            4280..4759
                     /locus_tag="J7W19_RS29335"
                     /old_locus_tag="J7W19_29335"
     CDS             4280..4759
                     /GO_function="GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA]"
                     /GO_process="GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025793.4"
                     /locus_tag="J7W19_RS29335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29335"
                     /product="deaminase"
                     /protein_id="WP_004938014.1"
                     /transl_table=11
                     /translation="MPLTEYHVTHGTRWPGRKAQPARPDWDTYFIEGAKWASTRADCTR
                     SQVGALLVDGNNELIKSGYNGAPAGVPGCASAGACPRGKLSAEECAPDSDYSNCISDHA
                     ERNAIRRCPPHELPNATLYSTRRPCPACWTLIEAAGICRVVWIEEDGEVTSTSLI"
     misc_feature    complement(4761..4778)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.25"
                     /tool="antismash"
     gene            4842..5237
                     /locus_tag="J7W19_RS29340"
                     /old_locus_tag="J7W19_29340"
     CDS             4842..5237
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29340"
                     /product="histone-like nucleoid-structuring protein Lsr2"
                     /protein_id="WP_078587588.1"
                     /transl_table=11
                     /translation="MALKTSKVTLVEATVDGVNYSGNVELTPAKMKGLEADAEAYEAAE
                     KEYEGQVEKLKKARDTAAEKFKKSLEAAGVRPIEPKKLTPDDLKKIRLWASRNGHTINP
                     KARIPGTIRAGYDKAAAEGKLQDDEKI"
     gene            5291..5656
                     /locus_tag="J7W19_RS29345"
                     /old_locus_tag="J7W19_29345"
     CDS             5291..5656
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29345"
                     /product="hypothetical protein"
                     /protein_id="WP_158688704.1"
                     /transl_table=11
                     /translation="MNKVVVIPANLGAPIEELEWPKDHGERLALVREKVQPAGDLMPVY
                     VPEAFNGYPLVLYVCEETQTTGPCEGNLRASLMITRITDELFPIYGNTLGVLIGPGGTE
                     LGFADDEIQQLRRLAAP"
     gene            5763..6956
                     /locus_tag="J7W19_RS29350"
                     /old_locus_tag="J7W19_29350"
     CDS             5763..6956
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605180.1"
                     /locus_tag="J7W19_RS29350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29350"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_040887462.1"
                     /transl_table=11
                     /translation="MTSAGERLKTVRKRRDLTQRELADASGVSISTLRRLEQGEQETAR
                     METWRKFAAALRVPTMTLVGDREQGPDEAGEPWEAVKKALNTPAALLESDDDAPTVEGV
                     TGALDDLARLVARDKYQDLANILPALLRDADALGTDGRELRVRALQRVGWLLIHTRQFT
                     AAEDALARSLEEATDRVQAAVTVDYMCWLLLRQGKLTDARELATQWADDTEPVRLTRAT
                     PVELALWGTLLLRLSGTAIRDNRSGEAEDALRYARAAAEALGREWRFPPNISNSTFGPV
                     TVLLKTAESAGIVGQPQGVLRIGDKVEKIRKAKSPRFRVQMTSSDWNRHLLDVSDAHAR
                     TGNYGVCVGKLSEINRSAPEWLPNQPFARDILGRVIEERRKLTPEMRDLATAVRLPL"
     misc_feature    complement(7071..7086)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            7329..7898
                     /locus_tag="J7W19_RS29355"
                     /old_locus_tag="J7W19_29355"
     CDS             7329..7898
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039764.3"
                     /locus_tag="J7W19_RS29355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29355"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_004938004.1"
                     /transl_table=11
                     /translation="MTASRPDAPPQHEKPIDLLEIARTVSRALSPVVSVPPNVETFTDQ
                     LRGHVHSLLVAIDEDGTNPQRLQLFTDAYRLMELTRTPAATPFYAWERMRGLAEVAQRL
                     AGLYELRNPTARPAPTSEPLPPREPASRRPMRRPPRGRMFVAPASTGERPTQVLLEQAE
                     APAESGHQKSSPRLAACEGQGDREPS"
     gene            7933..8145
                     /locus_tag="J7W19_RS29360"
                     /old_locus_tag="J7W19_29360"
     CDS             7933..8145
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29360"
                     /product="hypothetical protein"
                     /protein_id="WP_040887430.1"
                     /transl_table=11
                     /translation="MQEFSVECTEEGCGAEFDMKGGEALVERWKCRHMDRTGHRRFWET
                     WGRATILAPPPGAVVASQIVGHRAP"
     misc_feature    complement(8214..8232)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.94"
                     /tool="antismash"
     gene            8346..9566
                     /gene="fxlM"
                     /locus_tag="J7W19_RS29365"
                     /old_locus_tag="J7W19_29365"
     CDS             8346..9566
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378734.1"
                     /locus_tag="J7W19_RS29365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29365"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_004937996.1"
                     /sec_met_domain="PCMT (E-value: 4.6e-38, bitscore: 129.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEATAESERAAELRGAVVDRLKEDGTIVSPGVEAAMRKVPRHLS
                     VPEASLEDAYNTYDAVITQKDEHGNHISSVSAPQIQAMQLEQAGIRPGDNVLEIGTNGP
                     NAAYIAELVGPTGQVTTVDIDPAPAARAEQFLNQTGYTNVNVVVADGEDGFPKNAPFDA
                     IVVTVGAWDIPPAWVDQLKDDGRLVVPLRINGLTRTYGFLRQGDHLVATSAHVCGFVAV
                     RGAGTHHQQSMQLPGDEGVTLRFDEGPPADPSLLAGVLDGARAETWTGVTVANQEPIGT
                     LQMYLATHVPTYCSMSIDPEQTTGKIGPTNLGFSMVAIDGPNFGYIVVRRNTEKKNAEF
                     GFHAFGPDGAGFVERLADIVRAWSKHHRSGDPHIAVYPAGTPDDRISGDRIINKQHSRI
                     SISWPTT"
     gene            9624..9830
                     /locus_tag="J7W19_RS29370"
                     /old_locus_tag="J7W19_29370"
     CDS             9624..9830
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379227.1"
                     /locus_tag="J7W19_RS29370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29370"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_004937995.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.2e-13, bitscore:
                     49.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAVLDSVTAPIGLPAGDLTDEEFQLEVRVVVAESPVYNFDCPT
                     SDGCGNTCANGASSCVSTIEDAA"
     gene            10001..12964
                     /locus_tag="J7W19_RS29375"
                     /old_locus_tag="J7W19_29375"
     CDS             10001..12964
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378945.1"
                     /locus_tag="J7W19_RS29375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29375"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_004937990.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.2e-208,
                     bitscore: 691.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 7.4e-20,
                     bitscore: 70.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.2e-13, bitscore:
                     49.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDLDLYGDDVTAQGCQWLAEVWRDPIPDALAAASPVLCQRVAEI
                     LDGAPSDARRIRRVVRSVAAYLLRWNHRPTPFGVFAGVAPAVPAHTARVQWGDRYRTVL
                     RPDSDWLTDVITQLEADPAVLARLSVVANNTGRSRGTRHVVDGMPTDARTAGYAPVELS
                     VRRTRPVAAVLAAARTPIPYDVLVHSLTEQFPSARPDQLTGLIADLVSKHILISSLWPP
                     MTSVDTLHHLCNELEKAGTASIAELASQLASIRDGLNHPDADAPWTPGARLSLSMQRVS
                     ATGRVPLLVDAALDCALQVPEAVLNEAAEAAQVMHQLSPYPYGYPQWRDYHQRFLDRYG
                     NDAVVPVLDLVADSGLGMPAGFLGSERTRPPYQVTDRDEKVMRLLQEVILDASGELVLT
                     RATIADLTADHTEPLLPVPRAEIAVEIHAPTVEAVERGDYRLLVTGAPRPGSSMFGRFA
                     HLLPPPARAALTDSYATASPGAIPAQLSFAPRRRRNENVSRTAQVLPHMISLGQYHEPG
                     PGVIPLDDLAVTADDRRFYLVRMSTGQHVEPRVAHALEASVHTPPLARFLAEINTARSP
                     AYKTFTFGVANTLPYLPRVRYKRAILAPARWLLEAENLPTRSAPMADWNKALDRWRERL
                     HVPDHIALVENDQQLPIDLDQQIHRALLRSCVDRTRLVEVRETTTPQDRAWIGRPHQIL
                     IPLANSTLPDLTHRQIDVAVTSPLMPGRSPVLYARLFAHPQRYDEILTGHLPSLLDQFA
                     TVPPWWFRRHRDAAHPDSDQRLDLYLHLPGPDTFGPAAQQVHGWADTLHRQHLASHLEL
                     STYLPQAGRYGHGSALDAVHQVFAADSAASVTQIRAVADDVATGQALTAASMVDIVMQF
                     TGGPERAADWLTHALPREHGPLSRDRTALAQALADPARTALLALPGGPDIAASWQHRAA
                     ALRAYRDQLAAERDPDTVLRSLLDQHCIRALPVDPDHERAVRRLARACALRHRERQP"
     aSDomain        10388..10666
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_J7W19_RS29375_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="3.20E-22"
                     /identifier="RREFam001.1"
                     /label="J7W19_RS29375"
                     /locus_tag="J7W19_RS29375"
                     /protein_end="222"
                     /protein_start="129"
                     /score="70.0"
                     /tool="antismash"
                     /translation="VVANNTGRSRGTRHVVDGMPTDARTAGYAPVELSVRRTRPVAAVL
                     AAARTPIPYDVLVHSLTEQFPSARPDQLTGLIADLVSKHILISSLWPP"
     misc_feature    12743..12745
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12881..12883
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12961..14184
                     /locus_tag="J7W19_RS29380"
                     /old_locus_tag="J7W19_29380"
     CDS             12961..14184
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662446.1"
                     /locus_tag="J7W19_RS29380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29380"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_004937986.1"
                     /sec_met_domain="LANC_like (E-value: 6.1e-41, bitscore:
                     138.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITTTSPALLADAFARHLAVPAPPPEDRPWAAQTLATGAAGTALL
                     HIERARTGHGTWHQAHTWVKITVATDISAADTSGLYLGAPAVAFMLDCAVTADATRYQD
                     ALAVMDRHVIDLAHRRADAAEARMHGRGPASFHEYDIFYGLTGVGAYLLRQNPSGPAME
                     RVLNYLVRLTRPTRDQDHGELPGWWVGHRPDLTPATVPTGHANLGTAHGITGPLLLLAR
                     ALRQGVTVDGHGNAIDTILDWLDAWRQDGPAGPWWPEHLHLGELRAGHPAQRGPARPSW
                     CYGTPGIARAGQLAALARRDIARQRLFEDAMARCLTDPVQLSRLTDAGLCHGWAGVYQT
                     AWRAAHDAATPALRATLPGLAAALTQHARPGHDPGLLQGDAGTALALTTAAHDTAPTSG
                     WDACLLID"
     misc_feature    12985..12987
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14220..15167
                     /locus_tag="J7W19_RS29385"
                     /old_locus_tag="J7W19_29385"
     CDS             14220..15167
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955820.1"
                     /locus_tag="J7W19_RS29385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29385"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_325176101.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.3e-39, bitscore:
                     134.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEVLTGASTDTAAAHAGLEPVDLEAAVAVYQQAGQQALAQQTRP
                     PAWRQLYIQFTDWDKAEQTATDHIAPVLELAQQDRLITGWWFMRKHPCWRMRLLPAPKA
                     QFPPALADTLDALTADGRVHRWWPGIYEPESAAFGGDTSMTIAHTLFHSDSRAILTTAR
                     GELGRRELSLLLCATMMRAAGLEWYEQGDVWHRVSQERPLPPDVPVAKVQAMAGSLRHL
                     LLADTSPTSTMLQSDRTLKPAIDWVRAFRDAGKDLGTAAREGTLDRGLREVTSYHVIFH
                     WNRIGLPARTQSVLAHAARTAILHTADSSERLMP"
     gene            15164..16345
                     /locus_tag="J7W19_RS29390"
                     /old_locus_tag="J7W19_29390"
     CDS             15164..16345
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379191.1"
                     /locus_tag="J7W19_RS29390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29390"
                     /product="hypothetical protein"
                     /protein_id="WP_051072442.1"
                     /transl_table=11
                     /translation="MTAQHPEEGLHRLARRFPLVSRSHLVYPSFTARIEEVRACAEEST
                     QDKPLLDRINLACATWNLSALIASDCGLTDLATDLCLRQLRLFQAAWPVTGDTAIACLQ
                     PIINLVRLTARAADPHAAYQQLMSVYRAVHDGGTVIIHGHPIDLTGFTTDATRDHIEPW
                     LRSVLLEDGTRLLVATDQWPQAAEHATVYDTAPERLHDGRQVHVMASLHAADPDVANSL
                     IEKATITEPWEKAVAKILRHYADHRAGCVTAEGFTAVTGAVWDALEPTPPHLRMFRVRL
                     VLAAAELASEGCEAQVAPLHNAIVIDTTQSNDAYAAREILRRSVLPISERPRRELEAIV
                     CDGGLGRGALPETSLSTLMQAVSIAEASLTHCLADEEAVRPLEAPSCPASSAP"
     gene            16515..17414
                     /locus_tag="J7W19_RS29395"
                     /old_locus_tag="J7W19_29395"
     CDS             16515..17414
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29395"
                     /product="hypothetical protein"
                     /protein_id="WP_004937984.1"
                     /transl_table=11
                     /translation="MALADWGHIQFSGEITITRYVGEIGDDLREPLHCPECGTAERLTL
                     GTQGDEGLVVCPICGHEWTDSRVTARDVRQMLHLAAMGQPSAFPNGQMQTVVFPPLDED
                     RTLAPQPEWVDDDPRVRWELGCLISTGTMFTHCLRAARHLSSFAIASDTGVYTRLYPQA
                     GGSAVDAHMATVLVALSLYEIAFQARATKMFEIRLAQAVSALGPERARRVKDLRPIFDF
                     DPDAPCHLRVTDANRMDTAEAHDWERWRRTAVEILEFSIQDIVNHSHLSKSADEVRASD
                     RERQWYPDDLTWYTGNRV"
     misc_feature    complement(16528..16546)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.29"
                     /tool="antismash"
     gene            17535..17753
                     /locus_tag="J7W19_RS29400"
                     /old_locus_tag="J7W19_29400"
     CDS             17535..17753
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999023.1"
                     /locus_tag="J7W19_RS29400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29400"
                     /product="dodecin"
                     /protein_id="WP_004937981.1"
                     /transl_table=11
                     /translation="MGDHVYRVTEIVGSSTEGIDPAIRNGINRACQSLREVDWFEVTEI
                     RGHVENGQLAHFQVGLKVGFRLEDSSG"
     gene            complement(17750..19414)
                     /locus_tag="J7W19_RS29405"
                     /old_locus_tag="J7W19_29405"
     CDS             complement(17750..19414)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012464.4"
                     /locus_tag="J7W19_RS29405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29405"
                     /product="recombinase family protein"
                     /protein_id="WP_004937979.1"
                     /transl_table=11
                     /translation="MQIAPPKPGAGTRVLGVRRISHDTEASSALVRQKKEHDAAEKRFG
                     FHMVGDVEDATVSGSVNLADRPSLGKWMVSPKIHEWEALMVTAQDRITRDDWEWMAFLL
                     LCREHGKHVIILEEPSFDLYDRSSRMMSHFRSYKDSEYLDSIKKKKRDQVQDFRENGLW
                     PGGNWPFGYRTEKFFHEPSGKFRWKLVIDPVTSKLVREAYSRIVEQGWTTGRLVSDWNK
                     RKILSARDYQRHVNALEGRENVDVEVKGTFWSHGSMTKMLSKKQLIGQRVHKGEVIMGP
                     DGLPQKFCDPILTQAEFDALQAILKARGDRYRGKEKVGSGDLTGVLYCLCGRKQHELYS
                     QKKATKTQPAIKNYYAYFWCATKPATNMDACRFGLCWPQEQVKAELESAFLHRLGSIEI
                     KHKSFKPGVDNRPQIEEVKKGVDRLTSRLLKFDEDDPRYIAAEKLLEEHTATLKELEKN
                     PVVPSRWVEEGTGVTFGKRWGEMDWEQRGWLLKGLGVRFISAGTTKKPLYFLVHPDDVV
                     EKAHHAAGGIVDALNQEVWLKKVEEFQKIVAAMQLTA"
     gene            complement(<19505..19627)
                     /locus_tag="J7W19_RS29410"
                     /old_locus_tag="J7W19_29410"
                     /pseudo=""
     CDS             complement(<19505..19627)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135180.1"
                     /locus_tag="J7W19_RS29410"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29410"
                     /product="dodecin domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTNHTYRVTEIVGSSPEGVDQAIRNGLSRASQTLRNLDWSE"
     gene            complement(19812..21503)
                     /locus_tag="J7W19_RS29415"
                     /old_locus_tag="J7W19_29415"
     CDS             complement(19812..21503)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS29415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_29415"
                     /product="DUF6297 family protein"
                     /protein_id="WP_004937973.1"
                     /transl_table=11
                     /translation="MADALVGEPAAEAGPSASRAALEFLRRARREESRRRRRDGVVTLY
                     GVALTAVVWVPALIAVARAVNAASPQGAPAERVLAALPVTVPALGAAAFHALVRSAAWR
                     GPVLVDLPTVRWALPLPVDRGRLLLPRFARAAGLAAAVGAAAGAVLGLPAGTLSPGSGT
                     AGRAWAAAAGAWSGAAVALTAAGCGALVERYDGRGQGRSESRRSRVVGAVASAAVLAGL
                     ALAVVTAVDRDASPWTGRVLLWSGPWGWPAQPLVAAVGGPAPGWPAALALSVVSTAVVL
                     VAGARAVPAIPASALRARATVAERMTASVFSLELRQARLATRGGRSATRSRPVLRLPVP
                     RRRWLLVPWRDATGLLRAPARPVRALVRLAAAVALTALAPAARTTPRVVLAVLALTAAY
                     LSAAHLVEPARLDSDDLRRRVQLPYSSGALALWHAVVPAALLVPGLAAGAAVAVAAGRG
                     CAGLAVLVGCVPALVGAALVSAYRGALPPQAVVGTDTPFGNTAMFQLAGWYLRGPLGAL
                     VTTGPALALVLLHRGPAPAAVAGWLAAAGAAHLWWAHHTARRLHRT"
     gene            complement(21496..22182)
                     /locus_tag="J7W19_RS29420"
                     /old_locus_tag="J7W19_29420"
     CDS             complement(21496..22182)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354036.1"
                     /locus_tag="J7W19_RS29420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29420"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_004937971.1"
                     /transl_table=11
                     /translation="MPESPSGTPLLRMTDVGRDYGDRAVLRSVTLTLARAECLAVTGPN
                     GSGKSTLLRLATGRERPTSGEVLFDGVPVREDDPGVRRRLAAVMDAASFYPDLTVREHL
                     MFVALAHGLGRAAEDAVARVLADHRLAERADALPDALSSGQVQQALLASAFVRPHDLLV
                     LDEPEQRLDTAARAGLARRLRAHKAAGAAILLVTHDDELAAAVADHVLDLASGRVRAAA
                     EAVTGG"
     gene            complement(22244..22735)
                     /locus_tag="J7W19_RS29425"
                     /old_locus_tag="J7W19_29425"
     CDS             complement(22244..22735)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377607.1"
                     /locus_tag="J7W19_RS29425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29425"
                     /product="universal stress protein"
                     /protein_id="WP_004937966.1"
                     /transl_table=11
                     /translation="MNQEQPTPEHGSLPTGFERGTDGPKVIVVGVDGSESSWRAAAYAA
                     GLARRQNAMLAIVYVQPVLVGGAAFGAPVAEVTEEVAEELLAEIRATTERLRGLYPHAM
                     RWEFHTFRGDPYSGLVQAADDLKADAVVVGASEQAGHRIVGSVAVRLVKAGRWPVTVVP
                     "
     gene            complement(22920..23879)
                     /gene="egtD"
                     /locus_tag="J7W19_RS29430"
                     /old_locus_tag="J7W19_29430"
     CDS             complement(22920..23879)
                     /EC_number="2.1.1.44"
                     /GO_function="GO:0030745 - dimethylhistidine
                     N-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0052699 - ergothioneine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="egtD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638907.1"
                     /locus_tag="J7W19_RS29430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29430"
                     /product="L-histidine N(alpha)-methyltransferase"
                     /protein_id="WP_004937964.1"
                     /transl_table=11
                     /translation="MSQFVLSRTLPSDATAAALRADVAEGLTRSPKELPPKWFYDARGS
                     ALFDEITLLPEYYPTRAEREILSARAAAIAAATGARTLVELGSGSSEKTRHLIRALPLL
                     DHYVPVDVSESALSGAAATLLGEYPGLRVHALVADFQYGLALPDTPGPRLLAFLGGTIG
                     NLLPAERAEFLAGLRAGMAPGDALLLGTDLVKDERVLVAAYDDARGVTAAFNKNVLAVV
                     NRELGADFDPADFAHVALWDAHHEWIEMRLRARRAVLAKIPALDLAVHFAAGEEVRTEV
                     SAKFRREGVRSELAAAGLELRRWWTDDAGRFALSLSVP"
     gene            complement(23969..24712)
                     /gene="egtC"
                     /locus_tag="J7W19_RS29435"
                     /old_locus_tag="J7W19_29435"
     CDS             complement(23969..24712)
                     /GO_process="GO:0052699 - ergothioneine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="egtC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848212.1"
                     /locus_tag="J7W19_RS29435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_29435"
                     /product="ergothioneine biosynthesis protein EgtC"
                     /protein_id="WP_004937961.1"
                     /transl_table=11
                     /translation="MCRHLAVLGPEAPLGASVADPPHSLVRQSWAPRRQRYGTVNADGF
                     GIGWYADGDPRPARYRRAGPVWADPSFADLVRVVRSRALLAAVRDATGPGADGEAAAAP
                     FAAGPWLFSHNGALTGWPGSAAPLVPLLPAAALLRLEARCDAAFVWALVAHRLLDEGDP
                     PGRALAGAVTTLAEAAPGSRLNLLLTDGASVTATAHGDTLWYLAGPGERIAVASEPYDD
                     DPRWTEVPDGTLLSADRARVALTSL"
ORIGIN
        1 ggtgcagcag caggcccagc cctccggaga cggctacacc tgcgagcacg gcgcccggaa
       61 ctacaagaac ggcggatcgt gggaggccca gttctgcggc gccccacagg gcgttccgaa
      121 gtccgagcag tgccctccgc tgtggaagca gaaggacggc agtttcaagg ccaagtagcc
      181 ctctctcgct gactgttctc gtggcccggc ccgacgccgg gccccttctc actgaaagac
      241 atgcatgact gagatcgaat tccgttcgga catggacgtc gagctggtgg actccatggg
      301 cggagaccac agcatcgtcc gagcggcccg ggtgtcctcc ggcaccgagg caggagaccc
      361 ggccaaggac aagggcctga tcaatttcct ggcacgcgac cgacacggga gccccttcga
      421 ggccacggtg ttccagttca aggtcaccgt tccgttgttc gtcgcgaggg aatggttccg
      481 ccaccggatc ggctccttca acgaagtcag cggccggtac aaggagatgg agccggtctt
      541 ctacgtcccc gacgaaggcc gcccgctcaa gcagatcggc actcccggca agtacacctt
      601 cgaggccggg agcatcacac agggccggca cacccggaca gcacaccggc aggccgctca
      661 gactgcctgg gacgcctacc aagagcagct ggcactcggc gtcgctcggg aagtcgcccg
      721 caacgtcctg cccctgtccc tgtacacgtc cttctactgg acggtgaacg gccgctcgct
      781 gctgaacttc ctcagcctgc ggcgcgtcac cgcggacacc accgtcccga ccttccccct
      841 gtgggagatc gaccgggcag ccggccaagt cgaggagctt gcccagcagg tgactcccga
      901 ggcgttcgcc gccttcaaca agcacgggcg agtgaccccg tgaactggtg gatcgaagac
      961 gaagatgact gccgcgactg cggcggcacc cgatgcatag acgacaagga gaccaaatga
     1021 tcaagttcta ctacctcccc gactgcgccc cttgcgaggc gaccaagccg cgagccatcc
     1081 aggccgcgca gcaggccggg aaggacatcc tgttcatcaa cgcgcagacc cgtgcccccg
     1141 aagacctgca cgccgagggc gtcacgatcg cccccaccat cagcaacggc gtccggagca
     1201 tcaagggaga gcagaccttc gagcgcctgg tccgcttctt cgaggaggcc aactgatgga
     1261 gaccgcatcg gccatcctca tcggcgccaa cgctgccttc ctgttcctct tcgtcacggt
     1321 cgccgtcctc gcggcccgta aggggaagga atgagcttca acaacgtgat ccccggctgg
     1381 gtcgccgccc gcatggcaga gatcacaacc gagcggaccc tgctccacca gggcgctgtg
     1441 gccggccccc gggaggaccc ggacgggaac ccgaccgtgt tgctcaccgg cacctactac
     1501 gaggagcgat gcgagaggac cggcaaggtc acctcatcgc actccaacac cctgcacctg
     1561 acgttcgagg cggccgtgct cctgcgcgca caccttgacg aggccatcaa gacccaccgc
     1621 atttacaagg agttcaagcg tgcctgacta cggggccatg cccgacccgg atgagttcgc
     1681 tcagtacctg aaggactccg gattcaacac cctcgatgcc cagatgaacg aggccacgga
     1741 gacgatcgcc aaggtcatca cgaagggggc cgagttgaag aagcacgccc aggccaacgg
     1801 cttcagtgag gccgtggcag aggagatcgg attcgtcttc atcgagcggc tgatctcgaa
     1861 cgagggcggc tcgaagtgac ggacgctctg atcttcgtcg agtacccgga cagctccgtt
     1921 gacgagttca ccggagaggt cgtctacgaa cgggactgtg tcctcatcta cgaagagggc
     1981 ggcacaagtc accgcatcaa ccaccaccac acgcgcgccg tgcacgtgca cccgatatct
     2041 caggaggtct aaccatgttc gttctcaagt cccgactcgt cgccgcaatg cggctcatgg
     2101 tcgagcagga aaaggagctg gagttccgcg cagacgcgta cctgaagctg ctccagaaga
     2161 atgccgagct ggagactaac tactcgaagc tcgaaggcga gatccgcgag ctcaagctct
     2221 cgctccccgc ccgtgacgcc caggggcgct tctctaagcg ctgacacttg acatccacac
     2281 gataggggcc cgcttcggcg ggcccctcgt ttgttttact tggaggactt ccctagatga
     2341 tccgaatgtg cgtaaagatt gctggcgcac cagtagtgat caacgtactg gaggactctg
     2401 gggacatccc cgagttcgtt gagtgggtga ggcgcaacag gagtgcgctc ggctgtgaca
     2461 ccgagaccac cgggcttgac tggtgggccg acgacttccg gctccgcctc gtccagttcg
     2521 ggaaccatga cgagagctac gtactccccg tcgagctgag tgacgagctg ctgggcgccg
     2581 ccgtgggcgc catcaggttc gtgaacaagt tgatcttcca gaacggcagc tacgacctgt
     2641 tggtcctcga cgccacgacc gatctcacga tggaggagat ctggccgaag gtactcgata
     2701 cgaagatcct cgcccatctc gtggacagcc gcggcgaggc ggatgctgga atcggtcaca
     2761 gcctggcctc cctgactaag cactacatcg acgacggtgt ggccgcgaag atcaagggct
     2821 ccatggcgga gatcgcccgg agcctcaaga ccaccaaggc cagggtgtgg aagctggtcg
     2881 cctggaatca cggcggctat ctcacctaca gcggcctcga tccgatcctc gccttccgtc
     2941 tcggccgcat cctgataccg aagctgcccc gcacggtcta ccggaagacg gacatcgggc
     3001 ccggcatccc gccgatgaac ctcatcgagt tcgagcacaa ggtcgcggag atctgcgcgc
     3061 tcatgagccg tccaggcatc gcgctgaacc gggactacgc ccttcgcctg gaagcccgcc
     3121 tggcgctcga agagcaccgc tggaccgcac gggcccagga actcgggtgc gagaacccgt
     3181 ggtcgactga gcagtgcgcc gacgccttcg aggcgcgcgg tatcaccgtg ttcgacacga
     3241 caccgaccgg caaccggaag gtggacaagg tcttcctcgc cgattggagg gcgaggggtg
     3301 acgagctggc cgaggcgatc tatcaggcca aggccgcgcg caagaaacgc aacacctggc
     3361 tgcgcagctt cctggagtcc gtggactcca acggccgcat ccaccccagc atcaacagca
     3421 tccaggcccg cacagcccgc caaagcatcc aggggattcc cgctcagacc ctgccctccg
     3481 gcgactacga gatccgggcg tgcttcgagg ccaacgaagg ccacatcgtg ctctcgacgg
     3541 actactcgaa catggagttg aggttcttgg cggcccactc cggtgacaag cggatgctgc
     3601 gcgccttccg caacggcgag gacttgcacc aggtcaccgc gacggccgcc ggcgtctccc
     3661 gcaagctggg caaaatgacc aacttcttga tcgtcttcgg aggcggtccg gaggcgcttt
     3721 cgtcgcaggc cggcatcccg gtccacgaag cgaagcggat catggacatc ttcatggaga
     3781 cctatccggg tgtcgaagcc ttcatgaagc tcaagaccca ggaggcccgg cgtcaggggt
     3841 acgtcaccac gccaagcggc cggcgcctct acgtcgagaa gaagttcgcc ttccgcggta
     3901 ccaactattt cgtacagagc gggagtaggg acatcacttg ccgggccctg gtccggctgc
     3961 accacgccca tctcgcacag ttcgctctcc tcccgatcca cgacgagatc ctgttctcgg
     4021 taccgatcga gcacgccgac accgccgcca agatgaccga cgagctgatg aaggaaaccg
     4081 tcctgggcct ggagatcccg accgatccag atcgcggtgg aaagtcgtgg ggctcgctct
     4141 acatgaaggg tgtcgagaac ctgacgaagc tcgatgacta ctaccgggac aaccccgaac
     4201 aggcccttgc cgacgacagg cgccggaacc cagacgacca cgcagcagcc gcttgagcgg
     4261 cgctgaacag gaagaagaca tgccgctcac cgaataccac gtcacgcacg gcacccgctg
     4321 gcccggcagg aaggcccagc ctgctcgccc cgactgggac acgtacttca tcgagggcgc
     4381 caagtgggct tccacccgcg ccgactgcac ccgttcacag gtcggtgccc tcctcgtgga
     4441 cgggaacaac gagctaatca agtccggata taacggagca cccgccgggg tacccggctg
     4501 tgcttccgcc ggcgcctgcc cgcgcgggaa gctgagcgcc gaagagtgcg cccccgacag
     4561 cgactacagc aactgcatct cggaccatgc ggagcgcaat gcgatccgca ggtgtccgcc
     4621 gcatgagctt ccgaacgcga ccctgtactc gacaaggcgg ccgtgccccg cttgctggac
     4681 gctcatcgaa gcagccggta tatgccgtgt tgtctggatc gaagaagacg gtgaagtaac
     4741 ttcgacatcg ctgatctagc tttacatcca catcacttgc cgagtgacct tggttctatg
     4801 tagagtcttc ttcgtaagtt cacataggag ggagttcgag gatggcactc aagacatcta
     4861 aggtcacgct cgtagaggca accgtagatg gggtgaacta ctcggggaac gtcgaactca
     4921 cgcccgcaaa gatgaagggc ctggaggctg acgccgaggc gtacgaggcg gccgaaaagg
     4981 agtacgaggg ccaggtcgag aagctgaaga aggctcgcga cacggctgcc gagaagttca
     5041 agaagagcct ggaagccgct ggtgtccgtc cgatcgagcc gaagaagctc accccggacg
     5101 acttgaagaa gatccggctg tgggcgtccc gaaacggcca caccatcaac cccaaggccc
     5161 gcatccccgg cacgatccgc gcggggtacg acaaggccgc ggccgagggc aagctccagg
     5221 acgacgagaa gatctagatc aatcacatgg cgggggccgc actgggcggc cccttccagg
     5281 gaagtagtgc gtgaacaaag tagtagtcat accggccaac ctgggtgctc cgatcgagga
     5341 gcttgagtgg ccgaaggatc atggcgagcg cttggcgctc gtacgcgaaa aggtacagcc
     5401 agccggtgac ctgatgcccg tgtacgtccc cgaggcgttc aacgggtacc cgctcgtgct
     5461 gtacgtctgc gaggaaacgc agaccaccgg cccgtgcgag ggaaacctcc gggcctcact
     5521 gatgatcacc cgtatcacgg acgagctgtt cccgatctac ggaaacacgc tgggagtact
     5581 gatcgggcct ggcggcacgg agctgggctt cgctgacgac gagattcagc agctcaggcg
     5641 gctcgcggcg ccgtaactat ctgacggatc gtcagcttct cttgatccag cgacggatgc
     5701 ccctggagcg ctacaggggc atctgcttgg ggtcaagagc gcctgcgtcg tacgctcgtg
     5761 atatgacgag cgctggtgaa cgactcaaga cggtacgcaa gcgacgtgat ttgacccagc
     5821 gggagctggc agacgcttcc ggggtctcaa tctccaccct ccgccgcctc gaacaaggcg
     5881 aacaggagac ggcccggatg gagacctggc ggaagttcgc cgcggccctc cgggtgccca
     5941 ccatgaccct cgtcggtgat cgggagcagg ggccggacga ggcgggggag ccttgggaag
     6001 cggtgaagaa ggcactcaat acgcctgcgg cactcctgga gagcgacgac gacgccccca
     6061 ccgtggaagg ggtaaccgga gccctcgacg acctagcgcg actcgtcgcc cgcgacaagt
     6121 accaagacct ggccaacatc ctcccagcgc tacttcgaga cgctgacgcc ctcggcacgg
     6181 acggccgaga gctgcgcgtc cgtgcacttc agcgcgtcgg gtggctgctc atccacaccc
     6241 gccagttcac ggcggccgaa gacgccctgg cgcgctcact ggaagaggcc accgacaggg
     6301 ttcaggccgc cgtgacggtc gactacatgt gctggttgct gctccgtcaa ggcaagctca
     6361 ccgatgcccg cgagctggcc acccaatggg ccgacgacac tgaacccgtc cgcctgacca
     6421 gggccacccc tgtggagctg gccttgtggg gcacgctgct gctgcggctc tccggtacgg
     6481 cgatccggga caaccggagc ggagaagccg aagacgcctt gaggtacgca cgagctgctg
     6541 ctgaggcgct gggccgcgag tggcgattcc cgccgaacat cagcaactcc acgttcggac
     6601 cggtgaccgt tctgctcaag accgccgaga gcgccggcat cgtcgggcag ccgcaaggag
     6661 tgctgcggat cggcgacaag gtggagaaga tcaggaaggc caagagcccg cggttccggg
     6721 tgcagatgac atccagcgac tggaaccgtc accttctcga cgtgtccgac gcccatgccc
     6781 ggaccggtaa ctacggcgtg tgcgtaggga agttgtcgga gatcaaccgc agtgcgcccg
     6841 agtggctgcc caatcagcct ttcgcccggg acatcctcgg gcgagtgatc gaagagcgcc
     6901 ggaagttgac gccagagatg cgcgacctgg caactgccgt acgtctgccg ctctaaacga
     6961 tcactccggg tactttcgtc gcgtgggtat cgaaagtacc aacgacaggc ggcctggccc
     7021 ctcttagcgt gtctcgacac acagcacacg aggggcaggc gaagtgtagt gagacagagg
     7081 agtgacaccc gcgcgggcct gggtcggatg atggcccaac gcgacatgaa cggggcatta
     7141 ccggtttcga cgaccacccc cacccccttg tcggtcgggt gcgccgttcg cgccccgggc
     7201 gagtcggccg acggggccga ccttgccccg gggaccatgc gctaccccga ctgcacctgc
     7261 cgccagcacc gggacggcag gggaaagccg gactcgtcgg tccggctgct ggccagtggg
     7321 ggtgctcgat gaccgcaagc cgccccgacg ccccgccgca gcacgagaag ccgatcgacc
     7381 tgctggagat cgcacgcacc gtgagccggg ccctcagtcc agtggtgagc gtcccgccca
     7441 acgtggagac cttcaccgac cagcttcgcg ggcatgtgca ctccttgctc gtggcgatcg
     7501 atgaagacgg aaccaacccc cagcggctcc agctgttcac cgacgcctac cggctgatgg
     7561 aactcacccg caccccggcg gcgacgccgt tctacgcctg ggagcggatg cggggactgg
     7621 ccgaagtcgc gcagaggctc gcggggctgt acgagctccg gaacccgacc gcccgcccgg
     7681 ccccgacttc agagccgctg ccgccccggg aacccgcgag ccggcgcccg atgcgcagac
     7741 ctccgcgcgg caggatgttc gttgccccgg cctcgaccgg cgagcgaccc acccaggtac
     7801 tcctggagca ggcggaggca cccgcggaaa gcgggcacca gaagtcctcg ccccggctgg
     7861 ctgcctgtga ggggcagggc gaccgtgagc cgtcgtgacc ccgagtggac tacgacggag
     7921 gacccgggga ttttgcagga gttctccgtc gagtgcactg aggagggctg cggggccgag
     7981 ttcgacatga agggcgggga ggccctggtc gagcgctgga agtgccgcca catggaccgg
     8041 acgggtcacc ggcggttctg ggagacctgg gggcgcgcca cgatcctcgc tccgccgccc
     8101 ggcgcggtcg tcgcgagcca gatcgtaggc caccgggccc cctagaactc ctgcctctcc
     8161 ccttgtgtcc ccctcgggga gaggcgggtt ctccaactgg tcgcgcacgg ccccatctac
     8221 cgtattcaac aagccagttc gactactctt cgtgaagcct tggtccacgt taggtgtcct
     8281 agactcgggg cttcgatcac accagcacag ctctctgaag cagctcaggg aaggaaaact
     8341 gctccatgac cgaagcaacc gccgagtccg agcgcgccgc agaactgcga ggtgccgtcg
     8401 tggatcggct caaggaggac ggcacgatcg tgtcgcccgg cgtcgaggcc gccatgcgca
     8461 aggtcccgcg tcacctgtcc gtcccggagg cgtcgctcga agacgcctac aacacctacg
     8521 acgccgtgat cactcagaag gacgagcacg gcaatcacat cagttcggtg tccgctccgc
     8581 agatccaggc gatgcagctg gagcaggccg gcatccgccc cggcgacaac gtgctggaga
     8641 tcggcaccaa cgggccgaat gctgcctaca tcgcggaact ggtcggcccc acggggcagg
     8701 tcaccaccgt cgacatcgac cccgcgccag cagcccgcgc cgagcagttc ctcaaccaga
     8761 ccggctacac caacgtcaac gtggtcgttg ccgacggcga ggacggtttc cccaagaacg
     8821 cccccttcga cgcgatcgtg gtgaccgtcg gcgcctggga catcccgccc gcctgggttg
     8881 accagctcaa ggacgacggc cggctcgtcg tgccgctgcg catcaacggc ctgacccgca
     8941 cctacgggtt cctccggcag ggcgaccacc tggttgccac gagcgcccac gtgtgcggat
     9001 tcgtcgcggt acggggcgcg ggtacgcacc accagcagtc gatgcaactg cccggagacg
     9061 agggcgtcac cctgcgcttc gacgagggac cgcccgccga cccttcgcta ctggctggcg
     9121 tcctggacgg cgcccgcgcc gagacgtgga ccggggtgac cgtcgccaac caggagccca
     9181 tcggcaccct ccagatgtac ctggcgacgc acgtgccgac gtattgcagc atgtccatcg
     9241 accccgaaca gaccaccggc aagatcggcc ccaccaacct cggcttctcg atggtggcga
     9301 tcgacggacc gaacttcggc tacatcgtgg tgcgccgcaa cacagagaag aagaacgcgg
     9361 agttcgggtt tcacgctttc ggccctgacg gggcaggatt cgtcgagcgg ctggccgaca
     9421 tcgtccgcgc ctggagcaag caccaccgca gcggggaccc gcacatcgcc gtctacccgg
     9481 cgggcacacc cgatgaccgg atctccggcg accggatcat caacaagcag cacagccgga
     9541 tctcgatctc ctggccgacc acgtagaacg tggcgcctgg ccaggtctct cgcaccatcc
     9601 catcggatag agagagtgat cacatgacca ctgccgtact cgacagcgtc accgctccga
     9661 tcggactccc ggccggggat ctcaccgacg aggaattcca gctggaggtc cgcgtcgtcg
     9721 tcgccgagag ccccgtctac aacttcgact gccccaccag cgacggctgc ggcaacacct
     9781 gcgccaacgg ggccagctcc tgcgtctcca ccatcgaaga cgctgcctga cgcatccctg
     9841 tcgccggggc ggtagccgat cgtggctgcc gccccggcgc cacctatatg cacgccccca
     9901 tacgagaaga ggggtaccag tggcatacgg atcacccatc acgtaccggt ggcagccagg
     9961 aacactgcta cgcgcctcca ccgcctctcg acagataccc gtgccggacc tcgacctgta
    10021 cggcgacgac gtcaccgctc agggctgcca gtggctcgcc gaggtgtggc gcgacccgat
    10081 acccgacgcg ctggccgccg ccagccccgt cctgtgtcag cgcgtcgccg agatcctgga
    10141 cggtgccccc agcgatgccc gccgaatacg ccgggtcgtc cggtccgtgg cggcctatct
    10201 cctgcgctgg aaccaccggc ccacaccgtt cggggtgttc gccggggtgg cccccgcggt
    10261 gccggctcac acagcccggg tccagtgggg agaccggtac cggacggtgc tccggcccga
    10321 ttccgactgg ctgaccgacg tcatcaccca gctggaggca gaccctgctg tccttgcccg
    10381 gctgagcgtc gtcgccaaca acacgggccg ctcacgcggt acccggcacg tggtggacgg
    10441 aatgccgacc gacgcacgca ctgctggcta tgccccggtc gagctgtcag tccgccgcac
    10501 ccggcccgtg gcggccgtgc tcgccgccgc ccgcaccccg atcccgtacg acgtgctcgt
    10561 gcactccctg accgagcagt tccccagcgc gcgccccgat cagctcaccg gcctgatcgc
    10621 cgacctggtg agcaagcaca tcctgatcag ctctctgtgg cccccgatga catcggtcga
    10681 cacgcttcac cacctgtgca acgagctgga gaaggccggc accgccagca tcgcggaact
    10741 ggcgtcccag ctcgcgtcga tccgtgacgg cttgaaccat cccgatgccg acgccccatg
    10801 gacgcccggc gcccggctgt cgctcagcat gcagcgcgtg agcgctaccg gtcgcgttcc
    10861 gctgctggtc gacgccgccc tggactgcgc cctccaggtt cccgaagccg tgctgaacga
    10921 agccgccgaa gcggctcagg tcatgcacca gctgtcgccc tacccgtacg ggtatccgca
    10981 gtggcgcgac taccaccagc ggttccttga ccggtacggc aacgatgccg tcgtacccgt
    11041 gctggatctg gtcgccgaca gcggactcgg gatgccggcg gggttcctgg gctcggagcg
    11101 cacccggccg ccgtatcagg tgaccgaccg ggacgagaag gtcatgcgtc tgctccagga
    11161 ggtgatactc gacgccagcg gtgagcttgt cctgacccgg gcgacgatcg ccgacctgac
    11221 cgccgaccac acggaaccgc tcctgcccgt gccccgggcg gagatagccg tggagatcca
    11281 cgcccccacc gtggaagccg tagagcgcgg cgactaccgg ctactggtca ccggagcgcc
    11341 ccgccccggc agcagcatgt tcggccggtt cgcgcacctg ctcccaccgc ccgcgcgggc
    11401 cgcgctcacc gactcgtacg cgaccgcgag ccccggcgcg atcccggcac agttgtcgtt
    11461 cgcccctcgg cggcgccgca acgagaatgt atcccgcacc gcgcaggtgc tgcctcacat
    11521 gatttccctc ggccagtacc acgagcccgg ccccggcgtg atcccgctcg acgacctggc
    11581 ggtaaccgcg gacgatcgcc ggttctacct ggtccgcatg tcgaccggac agcacgtcga
    11641 accccgcgtt gcccacgcac tcgaagcatc cgtccacacg ccgccgctcg cacggttcct
    11701 ggcggagatc aacaccgccc gcagccctgc ctataagacg ttcaccttcg gcgtcgccaa
    11761 cacgctgccc tacctgccac gcgtccggta taagcgggcg atcctcgcgc cggcccgatg
    11821 gctgctggaa gccgaaaacc tacccacccg ctccgcgccc atggccgact ggaacaaggc
    11881 cctggaccgg tggcgcgaac ggctccacgt ccccgaccac attgccctgg tcgagaacga
    11941 tcagcagctc cccatagatc ttgatcagca gattcaccgg gccctgctcc gatcctgtgt
    12001 ggaccggacg cgccttgtcg aggtacgcga aaccacgacc ccgcaggacc gggcttggat
    12061 cggccgtcct caccagattc tgatccccct ggcgaactca acccttcccg atctgacgca
    12121 tcgtcagata gatgtcgctg tcaccagccc cctgatgccc ggccggtccc ccgtcctgta
    12181 cgcccgcctg ttcgcacacc cacagcggta cgacgagatc ctgaccggcc acctgcccag
    12241 cctgctcgac cagttcgcca ccgtgccgcc ttggtggttc cggcgtcacc gcgatgcggc
    12301 ccacccggac tccgaccagc gcctagacct ttacctgcac ctcccaggtc cggacacctt
    12361 tggcccggcc gctcagcagg tccacggctg ggccgacacc ctccaccgcc agcacctggc
    12421 ctcacaccta gagctgtcca cctacctgcc acaggccggc cgctacggac acggctccgc
    12481 cctggacgcc gtgcaccagg tcttcgccgc ggactcagcc gccagcgtga cccagatccg
    12541 tgccgtcgcg gatgatgtgg ctacggggca agccctcacc gctgcaagca tggtggacat
    12601 cgtcatgcag ttcaccggcg gcccggaacg ggcagccgac tggctgaccc acgccttgcc
    12661 ccgcgaacac ggtccgctct cccgagaccg gactgcgctt gcccaggccc tggccgaccc
    12721 cgcccgcacc gccctgctgg ccttacccgg agggccggac atcgcggcct cctggcaaca
    12781 ccgcgccgct gccctgcgcg cctaccgcga ccaactggcc gccgagcgcg accccgacac
    12841 cgtgttgcgg tcgctactcg atcaacactg catccgggct ttacccgtcg accccgacca
    12901 cgaacgcgcc gtccgccgac tcgcccgagc ctgcgccctg cgacaccggg agcggcagcc
    12961 gtgatcacca cgaccagccc ggccttactg gcggacgcct tcgccaggca cctggccgtc
    13021 cccgctccgc cgcccgaaga ccggccctgg gcagcgcaaa ccctggctac cggcgccgcc
    13081 gggaccgccc ttctccacat cgagcgcgcc cgcaccgggc acggcacctg gcaccaggcc
    13141 cacacctggg tcaagatcac cgtggccacc gacatcagcg ccgccgacac cagcggcctg
    13201 tacttgggag cgcccgccgt cgcgttcatg ctcgactgcg ccgtcaccgc cgacgcaacc
    13261 cgctaccagg acgccctggc tgtcatggac cgacacgtca tcgacctcgc ccaccggcga
    13321 gcggacgcgg ctgaggcccg catgcacggc agaggcccgg ccagcttcca cgagtacgac
    13381 atcttctacg ggctgaccgg cgtcggcgcc tacctgctcc gccagaaccc gtccggccct
    13441 gcgatggaac gcgtcctcaa ctacctcgtt cggctgaccc gacccacccg ggaccaggac
    13501 cacggggaac tgcccggttg gtgggtcggc caccgccccg acctcacccc ggccacggtc
    13561 cccaccggac acgccaacct cggcacggca catggcatca ccgggccgct gctgctcctt
    13621 gcccgcgccc tgcgccaggg cgtcaccgtc gacggccacg gaaacgccat cgacaccatc
    13681 ctcgactggc tcgatgcgtg gcggcaggac ggaccagcag gaccctggtg gcctgagcac
    13741 cttcacctcg gcgaactccg cgccggccac cccgcccaac ggggaccggc ccgacccagc
    13801 tggtgctacg gcacgcccgg catcgcccgc gccggacagc tcgccgccct cgctcgccgc
    13861 gacatcgcac gccagcgcct gttcgaggac gccatggccc gatgcctgac cgacccggtg
    13921 cagctatccc ggcttacaga cgcgggcctg tgccacggat gggcaggcgt ttaccagacc
    13981 gcatggcgcg cggcacacga cgctgccacc ccggccctac gtgccaccct gcccggattg
    14041 gccgccgccc tgacccaaca cgctcgcccc ggccacgatc cgggcctcct gcaaggcgac
    14101 gccggcactg ccctcgctct gaccaccgca gcccacgaca ccgcgccgac ctcgggatgg
    14161 gacgcatgtc tactgatcga ctaaaccgac ccgcccatct ggaagcgacc ctgcacgccg
    14221 tgctggaggt cctgaccggc gccagcacgg acaccgccgc agcccacgca ggactcgaac
    14281 ccgtcgacct ggaggccgca gtcgccgtct accagcaggc cgggcagcaa gcactcgccc
    14341 agcagacgag gcccccagcg tggcgtcagc tgtacatcca gttcaccgac tgggacaagg
    14401 ctgagcagac cgccaccgac catatcgccc ccgtcctgga actggctcaa caggacaggc
    14461 tgatcacggg ctggtggttc atgcgcaagc acccatgctg gcgaatgcga ctgctgccag
    14521 cccccaaggc gcagttcccg ccggcactgg ccgacacgct ggacgcactc accgccgacg
    14581 ggagagtcca ccgatggtgg cccggcatct acgaacccga aagcgcggcg ttcggcggtg
    14641 acaccagcat gaccatcgcc cacaccctgt tccactccga cagccgcgcc atcctcacca
    14701 cagcacgggg agaactgggc cgccgcgagt tgtcactgct gctgtgcgcc accatgatgc
    14761 gcgccgccgg actggagtgg tacgagcagg gcgacgtctg gcaccgcgtc tcccaggaac
    14821 ggcccctgcc cccagacgtg ccggttgcca aagtccaggc catggccggg agcctgcggc
    14881 atctactcct cgccgacacc agccccacca gcacgatgct ccagtcggac cggacgctca
    14941 agcctgccat cgactgggtc cgcgcgttcc gggacgcggg gaaagacctc ggcacagcgg
    15001 cccgtgaggg aaccctcgac cgcggcctgc gcgaggtcac gtcttaccac gtgatcttcc
    15061 actggaaccg gatcggactg ccggcccgca ctcagagcgt tctcgctcac gcggcacgta
    15121 ccgcgatcct gcacaccgct gactcctcgg agaggctgat gccgtgaccg cgcaacatcc
    15181 ggaggagggg ctccaccggc tcgccaggcg gtttccgctg gtcagccgct cccacctcgt
    15241 ctatcccagc ttcaccgccc gcatcgaaga ggtacgcgcc tgcgcagagg agtcgactca
    15301 ggacaagccg cttctcgacc ggatcaacct cgcgtgcgcc acctggaatc tgtccgcact
    15361 gatcgcctcc gactgcggcc tcacagactt ggcgacagac ctgtgcctgc ggcagctccg
    15421 cctcttccag gcagcatggc ccgtcaccgg ggacaccgcc atcgcctgtc tccagccgat
    15481 catcaacctc gtacgcctga ccgcccgagc ggcagacccg catgccgcct atcagcagct
    15541 gatgagcgtg taccgcgccg tccatgacgg cggcaccgtg atcattcacg gtcatcccat
    15601 cgacctcacg ggcttcacca ccgacgcgac ccgggaccac atcgagccct ggctacgatc
    15661 cgtcctgctc gaagacggca cacgcctcct ggtcgccacc gatcaatggc cccaagcagc
    15721 agagcacgcg accgtttacg acacggcgcc cgaacgactg cacgacggta ggcaggtgca
    15781 tgtcatggca agcctgcacg ccgccgaccc ggacgtcgcc aattccctga tcgagaaggc
    15841 cacgatcacc gagccatggg agaaggccgt cgcgaagatc ctccgtcatt acgccgacca
    15901 ccgtgcgggc tgcgtcacgg cagaggggtt cacggcggtg acgggtgctg tgtgggatgc
    15961 tctggaaccg actccaccgc acctgcgtat gttccgggtg aggctggtcc tggcggcggc
    16021 cgagctggca tcagaaggct gcgaagccca ggtggccccc ctgcacaacg cgatcgtcat
    16081 cgacaccaca cagtcgaacg acgcgtacgc tgcgcgcgag atcctgcgcc gctccgtctt
    16141 gccgatcagc gagcggccac gtcgtgagct ggaagcgatc gtctgtgacg gcggactcgg
    16201 ccggggggcc ctgccggaga cgtcgctgtc cacgctgatg caggctgtca gcatcgccga
    16261 agcgagcctc actcattgtc ttgccgatga agaggcggtg aggccgctgg aagctccatc
    16321 atgtccagcg tccagtgcac cgtagtgatc ggctctgcat cgtcgagctc ctagccgtga
    16381 tggacgacct caccctgctg catgacgcct acctctccac cctcgatttg ccggaagcat
    16441 gatcaggtct tggcaaccgc cgtcgagcgg ggtgagatgg ccctacgggg ccgatcactg
    16501 gggcagggga cgcaatggcg ctggcagact ggggtcacat tcagttctcg ggcgaaatca
    16561 cgatcaccag gtacgtggga gagatcgggg acgacctgcg cgagcccctg cactgcccag
    16621 agtgcggaac ggcagaacgg ctcaccctcg gcacacaagg ggatgagggc ctggtcgtgt
    16681 gccccatctg cggccacgag tggacagata gccgggtcac tgcacgtgac gtgaggcaga
    16741 tgctccacct cgccgccatg ggacagccgt cggccttccc gaatggtcag atgcagaccg
    16801 tcgtctttcc cccgctggac gaagatcgga ccctcgctcc gcaaccggag tgggtcgatg
    16861 acgacccgcg ggtccggtgg gaactcggct gcttgatctc cacagggacg atgttcaccc
    16921 actgcctccg cgccgcccgg catctgtctt ccttcgccat cgcctcggac acaggtgtct
    16981 acacccgtct ctatccccaa gccggcggca gcgctgtcga cgcccacatg gcaacggtgc
    17041 tcgtagccct gtctctgtac gagatcgcgt tccaggcgcg agccacgaag atgttcgaga
    17101 tccggctggc gcaagcagtc agcgcactcg gccctgagcg cgctcgcaga gtgaaggacc
    17161 tgcggccgat cttcgacttc gaccccgacg caccgtgcca tctgcgcgtg accgacgcga
    17221 accgcatgga cacggccgaa gcgcacgatt gggagcgatg gcgcaggacc gccgtggaga
    17281 tcctggagtt cagcatccag gacatcgtca accactcaca cctgtcgaag tcggccgacg
    17341 aggtacgtgc tagcgatcgg gaacgccagt ggtacccgga tgatctgacc tggtacacgg
    17401 ggaaccgggt ttaagtaagg aaaagccccc tgttcctatc gcgtgggaac agggggctca
    17461 agctgcccgc ctcgactcgc gccgcccccc ggttccgtgc actgtggatg catcggaacg
    17521 aaggagcggc cgacatggga gaccacgtct accgagtcac cgagatcgtt ggatcatcca
    17581 ccgaaggaat cgacccagct atccggaacg gcatcaaccg tgcctgccaa agtctccgcg
    17641 aggtcgattg gttcgaagtc accgagatcc gcggccacgt cgagaacgga cagctagccc
    17701 acttccaggt cggcctgaag gtcggcttcc gtctggagga ctccagcggc taggcagtga
    17761 gctgcatcgc agccacgatc ttctggaact cctcgacctt cttgagccag acctcctggt
    17821 tcagggcatc cacgatgccg ccggccgcgt ggtgggcctt ctcgaccacg tcgtcggggt
    17881 gcacgaggaa atacaggggc ttcttcgtcg tgccagccga gatgaagcgg acccccaggc
    17941 ccttcagcag ccaacctcgc tgttcccagt ccatctcgcc ccagcgcttc ccgaaggtca
    18001 cgccggtccc ttcttcgacc catcgagacg gaaccacggg gttcttctcc agttccttga
    18061 gcgttgctgt gtgctcttcg agaagcttct cagccgcaat gtaccgaggg tcgtcctcat
    18121 cgaacttcag gaggcgactg gtcagccggt ccacgccctt cttgacctcc tcaatctgcg
    18181 gacggttgtc cacgccgggc ttgaaggact tgtgcttgat ctcgatgctc ccgaggcggt
    18241 gcaggaacgc agactccagc tcggccttca cctgctcctg gggccagcag agtccgaagc
    18301 ggcaggcatc catgttggtt gcaggcttcg tggcgcacca gaagtaggcg tagtagttct
    18361 tgatcgcagg ttgtgtcttt gtagccttct tctggctgta cagctcgtgc tgcttgcgac
    18421 cgcacaggca gtagagaacc ccggtcagat caccggaccc caccttctcc ttcccgcggt
    18481 acctgtcgcc ccgcgccttg aggattgcct ggagagcgtc aaactccgcc tgcgtaagga
    18541 tcgggtcgca gaacttctgc ggaagaccat cggggcccat gatgacctcg cccttgtgga
    18601 cccgttgccc gatgagctgc ttcttcgaga gcatcttcgt catggatccg tggctccaga
    18661 aggtcccctt gacctccaca tccacgttct cgcgaccttc aagcgcgttg acgtggcgct
    18721 ggtagtcgcg ggcgctgagg atcttccgct tgttccagtc cgagaccaga cggccagttg
    18781 tccagccctg ctcaacgatc ctggagtacg cctcacgaac cagcttgctg gtcacggggt
    18841 caatgacaag cttccaccgg aacttcccag aaggctcatg gaagaacttc tcggtccggt
    18901 atccgaaggg ccagttccca ccaggccaga gcccgttttc gcggaagtct tgaacctggt
    18961 cgcgcttctt cttcttgatc gagtccaggt actccgagtc cttgtacgac cggaagtggg
    19021 acatcatccg ggagctgcga tcgtagaggt cgaagctcgg ctcttcgagg atgatcacgt
    19081 gcttgccgtg ctcgcggcac agcagcagga aggccatcca ctcccagtcg tcacgggtga
    19141 ttcgatcttg agccgtgacc atgagcgctt cccactcatg gatcttggga gagaccatcc
    19201 acttcccgag cgaggggcgg tctgccaggt tcactgaacc ggagactgtg gcgtcttcaa
    19261 cgtcgccgac catgtggaag ccgaagcgct tctcagctgc gtcgtgctcc ttcttctgcc
    19321 gaacgagggc ggagctcgcc tcggtgtcgt ggctgatgcg tcgaacgcca aggacccggg
    19381 tgccggcgcc gggcttgggt ggtgctatct gcatgagagg gtgcttgcct tacgtctctg
    19441 atcacacccc ccgcccgcaa tggtaaagga ccggtcaagc ggggaggggt tttgtgatct
    19501 gttcctccga ccagtcgagg ttgcgcagcg tctgcgacgc gcgggacagg ccgttgcgga
    19561 tggcctggtc gacgccctcg ggggacgagc cgacgatctc ggtcacgcgg tacgtgtggt
    19621 tcgtcatggg tgggggtcct cccggcggcg cgcgtgctgc tgaccccacc accgtccggc
    19681 acaccgcgtg tccgcgcgag gcgggcgccg ccgttggcgt ggtcgcgagt ccggggggtg
    19741 cggcggcgcc gggtggggca tggcgggggc agcggccccc ggggcgcgtc cggtccgtca
    19801 cccccgctcg gtcacgtccg gtggaggcgg cgggccgtgt ggtgggccca ccagaggtgt
    19861 gcggcgcccg ccgccgcgag ccagccggcc acggccgccg gggcggggcc gcggtggagg
    19921 aggacgaggg cgagcgccgg tccggtggtg accagggcgc cgagggggcc gcgcagatac
    19981 cagccggcca gctggaacat ggccgtgttc ccgaacggag tgtccgtccc caccaccgcc
    20041 tgcggcggca gtgctccccg gtacgcgctg accagggccg cgccgaccag ggcggggaca
    20101 cagccgacga gcaccgcgag accggcgcag ccccggccgg ccgccaccgc caccgccgcg
    20161 cccgccgcca gcccggggac cagcagggcg gccgggacga cggcgtgcca cagggccagg
    20221 gcgccggagg agtacgggag ctggacgcgg cggcggaggt cgtcgctgtc caggcgggcg
    20281 ggctcgacga ggtgggcggc cgacaggtac gcggcggtca gcgcgaggac ggccaggacg
    20341 acccgcgggg tcgtccgcgc cgccggggcg agggcggtga gggccaccgc cgccgcgagc
    20401 cggaccagcg cccgtaccgg ccgggccggc gcccggagca gccccgtcgc gtcccgccac
    20461 ggtacgagca gccaccgccg gcgcggcacc ggcagccgca ggacggggcg ggaacgggtc
    20521 gccgagcgcc cgccgcgcgt cgccagccgt gcctggcgca gctccaggga gaacacggac
    20581 gccgtcatcc gctcggccac cgtggcccgg gcgcgcaggg ccgacgccgg tatcgccggc
    20641 accgcccgcg cgcccgccac cagcaccacc gccgtcgaga ccaccgacag cgcgagggct
    20701 gccggccacc ccggggccgg gccgcccacg gccgccacca gcggctgcgc cggccagccc
    20761 cacggacccg accacaggag tacccgcccg gtccaggggc tcgcgtccct gtccaccgcc
    20821 gtcacgacgg ccaaggccag tcccgcgagg accgccgccg aggcgaccgc tccgacgacg
    20881 cgggaacggc ggctctccga ccggccctgc ccccggccgt cgtaccgttc gacgagcgcg
    20941 ccgcagcccg ccgcggtgag cgcgacggcc gcgccgctcc aggcccccgc cgccgcggcc
    21001 cacgcccggc cggcggtacc ggatcccggc gagagcgtcc cggccggcag ccccaacacc
    21061 gcgcccgccg ccgcgccgac ggccgcggcg agaccggcgg ccctcgcgaa ccgggggagc
    21121 agcagccggc cgcggtccac gggcagcggc agagcccacc ggacggtggg caggtccacc
    21181 aggaccggtc cccgccaggc cgcgctgcgg accagcgcgt ggaaggcggc ggcgccgagg
    21241 gccgggacgg tcaccggcag ggcggccagg acccgttccg cgggcgcgcc ctgcggggac
    21301 gcggcgttca cggcccgggc gacggcgatc agcgcgggca cccacacgac ggccgtcagc
    21361 gcgacgccgt acagcgtcac gacgccgtcg cgccgccgtc ggcggctctc ctcgcggcgg
    21421 gcgcggcgca ggaactccag cgcggcgcgg gaggcggagg gaccggcctc cgcggccggt
    21481 tccccgacga gcgcgtcagc caccggtcac cgcctccgcg gcggcgcgga ccctgccgga
    21541 ggccaggtcc aggacgtggt cggccaccgc cgccgccagc tcgtcgtcat gcgtgaccag
    21601 caggatcgcg gcgcccgccg ccttgtgggc gcgcagtcgc cgggccagtc cggcgcgggc
    21661 cgcggtgtcc agccgctgct cgggctcgtc gagcaccagc aggtcgtgcg ggcgtacgaa
    21721 ggccgaggcc agcagcgcct gctggacctg tcccgacgac agcgcgtccg gcagcgcgtc
    21781 cgcacgctcc gccagccggt ggtcggcgag gacccgcgcc accgcgtcct ccgccgcccg
    21841 gcccaggccg tgcgccagcg cgacgaacat caggtgctca cggacggtca ggtccgggta
    21901 gaaggacgcg gcgtccatga cggcggcgag ccggcgccgc acgccggggt cgtcctcgcg
    21961 cacgggcacg ccgtcgaaca ggacctcgcc cgacgtgggc cgttcccggc cggtcgccag
    22021 gcgcagcagc gtcgacttgc ccgagccgtt ggggccggtg acggcgaggc actcggcgcg
    22081 cgccagggtc agggtgacgg agcggagtac ggcgcggtcg ccgtagtcgc ggccgacgtc
    22141 cgtcatccgg aggagcggtg tcccggacgg ggactcgggc atggcggggt tcctcccctg
    22201 ggtggtgctg gtggtgctga acgtccgtgg gggacggggg tgcctacggg accaccgtca
    22261 ccggccaccg gcccgccttc accaggcgga ccgcgaccga gccgacgatg cggtggcccg
    22321 cctgttccga cgcgccgacg acgaccgcgt cggccttgag gtcgtcggcc gcctgcacca
    22381 ggcccgagta cgggtcgccg cggaaggtgt ggaactccca gcgcatggcg tgcgggtaga
    22441 ggccgcgcag ccgctcggtg gtggcgcgga tctccgcgag cagttcctcg gcgacctcct
    22501 cggtcacctc ggccaccgga gccccgaacg ccgcgccgcc caccaggacg ggctgtacgt
    22561 agacgatggc gagcatcgcg ttctgccggc gggccagccc ggcggcgtag gcggcggcac
    22621 gccaggagga ctcggagccg tccaccccga cgacgatcac cttggggccg tcggtgccgc
    22681 gttcgaagcc ggtcggcagg ctgccgtgtt cgggggtggg ctgctcttgg ttcacggggt
    22741 caggttaccc gggggttggt ttcgccccgg tccctccccc agaggggcac ccccaacggg
    22801 ctgattccag cccgtccggc gtttgaggac gagcggcgga gccgcgaaaa ggggcctggg
    22861 gcgcagcccc aggaagcggc gaaggggcgg gaccggggca ccagcccgcc gcaggcgccc
    22921 tacggcaccg acagcgacag cgcgaagcgc cccgcgtcgt ccgtccacca ccgtcgcaac
    22981 tccaatcccg cggcggcgag ttccgaccgt acgccctccc gtcggaactt cgcggacacc
    23041 tccgtccgca cctcctcgcc ggcggcgaag tgcaccgcca ggtccagcgc cgggatcttc
    23101 gccagcacgg cccgccgggc ccgcagccgc atctcgatcc actcgtggtg ggcgtcccac
    23161 agggccacgt gcgcgaagtc ggcgggatcg aagtcggcgc ccagctcccg gttgacgacc
    23221 gcgaggacgt tcttgttgaa ggccgccgtc acgccccgcg cgtcgtcgta cgccgcgacc
    23281 agcacccgct cgtccttgac caggtccgtg ccgagcagca gggcgtcgcc gggggccatg
    23341 ccggcccgca ggccggccag gaattcggcg cgttccgcgg gcagcaggtt gccgatggtg
    23401 ccgccgagga acgcgagcag ccgcggcccg ggggtgtccg gcagggcaag gccgtactgg
    23461 aagtcggcga cgagggcgtg cacccgcagc ccgggatatt cgccgagcag cgtcgcggcg
    23521 gccccggaca gggcgctctc gctgacgtcc accggcacgt agtggtccag caggggcagc
    23581 gcccggatga ggtggcgggt cttctccgag gagccggagc cgagttcgac gagcgtgcgg
    23641 gcgccggtgg cggcggcgat ggcggccgca cgggcgctca ggatctcgcg ttcggcgcgc
    23701 gtcgggtagt actcgggcag cagcgtgatc tcgtcgaaga gggcgctgcc ccgcgcgtcg
    23761 tagaaccact tcggcgggag ctccttgggc gaccgggtca gcccctcggc gacgtcggcg
    23821 cgcagggcgg cggcggtcgc gtcggacggg agggtgcggg agaggacgaa ctggctcacg
    23881 ggcagggctc cttgcgcgtg cggcggggca ggggaaagga aggcggagct cgacagggga
    23941 ctcgaaaggg gactcgaaaa gggaggggct acagggacgt gagggcgacc cgcgcgcggt
    24001 ccgccgacag cagcgtgccg tcgggcacct cggtccagcg cggatcgtcg tcgtacggct
    24061 ccgacgccac cgcgatccgc tcgccgggcc ccgccaggta ccacagggtg tccccgtgcg
    24121 cggtggccgt gaccgaggcg ccgtcggtga gcaacaggtt cagccgggag ccgggcgcgg
    24181 cctccgcgag ggtggtgacg gcgcccgcga gcgcccgccc gggcggatcg ccctcgtcca
    24241 gcagccggtg cgccaccagc gcccagacga acgccgcgtc acagcgggcc tccagccgca
    24301 gcagggcggc ggcgggcagc agcgggacga ggggcgcggc cgagccgggc cagccggtga
    24361 gcgcgccgtt gtggctgaac agccacgggc ccgcggcgaa gggggccgcg gcggcctcgc
    24421 cgtcggcgcc cggcccggtc gcgtcccgca ccgccgccag cagcgcccgg ctccggacca
    24481 cccggaccag gtcggcgaag gacgggtccg cccacaccgg cccggcccgg cggtaccggg
    24541 cgggccgcgg gtcgccgtcc gcgtaccagc cgatgccgaa cccgtccgcg ttcaccgtcc
    24601 cgtaccgctg ccggcgcggc gcccacgact gccggacgag ggagtgcggc gggtcggcga
    24661 cggacgcgcc gagcggggcc tcgggaccca gcacggccag gtgccggcac atcagcacgg
    24721 ctccgggtcg cgggccgtgc ggaaaccggc gaagatctgc cggcgcaccg gcaggtccca
    24781 gttgcggaac gtgccccggc aggcgaccgg gtccaccccg aacgacccgc cgcgcagcac
    24841 cttgtacgcg ctgccgaaga agacctccga gtactcgcgg taggggaacg cccggaagcc
    24901 cgggtacggc aggaagtcgc tcgccgtcca ctcccacacg tcgccgatca gctgccggac
    24961 gcccagcggg gacgcgccgc gcggataggc gccgacgggg gccgggcgca ggtggcgctg
    25021 gccgaggttg gcgtgctcgg gggtggggtc ggcgtcgccc cacgggtagc ggcgggagcg
    25081 gccggacgcc gggtcgtacc gggcggcctt ctcccactcc gcctccgtgg gcagccgccg
    25141 cccggcccag gcggcgtacg cggcggc
//
