LOCUS       NZ_CP072827            22546 bp    DNA     linear   CON 18-JAN-2024
DEFINITION  Streptomyces mobaraensis NBRC 13819 = DSM 40847 chromosome, complete
            genome.
ACCESSION   NZ_CP072827
VERSION     NZ_CP072827.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces mobaraensis NBRC 13819 = DSM 40847
  ORGANISM  Streptomyces mobaraensis NBRC 13819 = DSM 40847
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7574085)
  AUTHORS   Li,P.
  TITLE     Telomere system of Streptomyces mobaraensis DSM40847 linear
            chromosome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7574085)
  AUTHORS   Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2021) Institution of Microbiology, Jiangxi Academy
            of Science, Changdong Road 7777, Nanchang 330012, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly         :: AORZ00000000
            Genome Coverage                   :: 60.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/18/2024 06:31:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,545
            CDSs (total)                      :: 6,448
            Genes (coding)                    :: 6,310
            CDSs (with protein)               :: 6,310
            Genes (RNA)                       :: 97
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 23 of 138
            Pseudo Genes (incomplete)         :: 120 of 138
            Pseudo Genes (internal stop)      :: 5 of 138
            Pseudo Genes (multiple problems)  :: 9 of 138
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:35:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5813935
            Orig. end                         :: 5836481
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072827.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22546
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="21"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22546
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22546
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12546](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12546)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    481..497
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.27"
                     /tool="antismash"
     misc_feature    complement(482..497)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.07"
                     /tool="antismash"
     gene            complement(705..1796)
                     /gene="zapE"
                     /locus_tag="J7W19_RS25135"
                     /old_locus_tag="J7W19_25135"
     CDS             complement(705..1796)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /gene="zapE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325992.1"
                     /locus_tag="J7W19_RS25135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25135"
                     /product="cell division protein ZapE"
                     /protein_id="WP_004956027.1"
                     /transl_table=11
                     /translation="MSSSTAASPEPRPTGEQPVALTSRTPHVPAERLVAEMVPPPRFDA
                     VRFDTYIPDPNQPSQTEAVRVLSGFAAGLGSPAAGSGRKRWFRREAKPAPAGPRGVYLD
                     GGYGVGKTHLLASLWHAAPAAPERKAFGTFVELTNLVGALGFQQTVRTLGGHELLCIDE
                     FELDDPGDTVLVSTLLGKLVEQGVALAATSNTLPGKLGEGRFAAADFLREIQGLSAHFR
                     ALRIDGEDYRHRGLPEAPAPFDDETVKRVAYSVDGASLDDFPALLRHLSQVHPSRYGAL
                     CDGVRAVCLTGVEPVPDQSTALRLVVLADRLYDREVPVLASGRPFDRLFSEEMLAGGYR
                     KKYFRAISRLTALARDAKSLADG"
     gene            1893..2720
                     /locus_tag="J7W19_RS25140"
                     /old_locus_tag="J7W19_25140"
     CDS             1893..2720
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325993.1"
                     /locus_tag="J7W19_RS25140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25140"
                     /product="pyrimidine reductase family protein"
                     /protein_id="WP_004956024.1"
                     /transl_table=11
                     /translation="MRRLFPSPTAPADLQDREWGLDELADLYAYPGAVADGRPWLRANM
                     VSSLDGAAHHEGRSQPLSSAADMRIFGTLRALADAVVVGAETVRQEGYRPARVREAFAA
                     RRAALGQSPAPVIAVVSAGLDLDFALPLFAEPLVPTLVLTGEAAPAERRDAAAAAGVEV
                     VVAGEGRTVDVARVPELLAARGMTRLLTEGGPRLLGQFTAAGVLDELCLSLAPMVAAGV
                     APRIAGGPPLEVPRRFALASVLEQDGFLFTRYRRGTGGPAAGAAAAGAGGIGI"
     misc_feature    complement(2746..2766)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            2879..3376
                     /locus_tag="J7W19_RS25145"
                     /old_locus_tag="J7W19_25145"
     CDS             2879..3376
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669466.1"
                     /locus_tag="J7W19_RS25145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25145"
                     /product="hypothetical protein"
                     /protein_id="WP_040892836.1"
                     /transl_table=11
                     /translation="MFTSVLMIEQPLSATDVDFVTGLHDEEMSFVVLMQPRGAEDRLLR
                     AIDDVALGELEQAVHEADEPEGEAALRPAALALEHSLRLLRGAGSEAVGQIIDDHPLDL
                     LRSVVEQTHADEVIVLTAPHLVEEFFHRDWASRARHKVGVPVLKLYAHADADEERSAAD
                     VE"
     gene            3608..5005
                     /gene="murC"
                     /locus_tag="J7W19_RS25150"
                     /old_locus_tag="J7W19_25150"
     CDS             3608..5005
                     /EC_number="6.3.2.8"
                     /GO_function="GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="murC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003993768.1"
                     /locus_tag="J7W19_RS25150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25150"
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="WP_004956019.1"
                     /transl_table=11
                     /translation="MAPAVPTTMDRPHFIGIGGAGMSGIAKILAQRGARVAGSDAKESA
                     TAAALRALGVTVHIGHAAGHLAEDASCVVVSSAIRQDNPELAAAAERGIPVVHRSDALA
                     RLMDGLRPIAVAGTHGKTTTTSMLAVALDALALDPSYAIGGDLHGPGTNARHGAGEIFV
                     AEADESDRSFHKYAPEVAIILNAELDHHANYASMEEIHESFEIFVGRIRPGGTLVVSAD
                     QEGARELTRRLAGRTGDVRVVTYGESEDADVRILDVTPRGLTSEVTVLLDGRELSFGVS
                     VPGRHYANNAVAALAAGVALGVPADDLAAALGKYTGVGRRLQLKGEAAGAQVIDSYAHH
                     PTEMTADLEAMRGAAAGSRVLVVFQPHLFSRTQELGTEMGRALALADASVVLDIYPARE
                     DPIPGVTSAMIIDAAREAGADVRAEHDMAAVPDVLAGMVRPGDLVLTMGAGDVTDLGPR
                     ILARLES"
     gene            5028..5435
                     /gene="msrB"
                     /locus_tag="J7W19_RS25155"
                     /old_locus_tag="J7W19_25155"
     CDS             5028..5435
                     /EC_number="1.8.4.12"
                     /GO_function="GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981915.1"
                     /locus_tag="J7W19_RS25155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25155"
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="WP_004956016.1"
                     /transl_table=11
                     /translation="MPYEVEKTDEQWRAELTPAEYQVLRRAGTEPAFRGEYTDTTTAGV
                     YSCRACGAELFRSTEKFASHCGWPSFYDPKDSDAVELLEDRSHGMVRTEVRCARCGSHL
                     GHVFEGEGYPTPTDQRYCINSIALRLEPAEG"
     gene            complement(5699..7441)
                     /gene="treZ"
                     /locus_tag="J7W19_RS25160"
                     /old_locus_tag="J7W19_25160"
     CDS             complement(5699..7441)
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133692.1"
                     /locus_tag="J7W19_RS25160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25160"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_004949354.1"
                     /sec_met_domain="CBM_48 (E-value: 0.0001, bitscore: 21.1,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 3.7e-10, bitscore:
                     38.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYEVWAPHTRRVTLHTDDGTHPMHRTHAHEGWWQREAPGTEGTR
                     YRFALDDGPLRPDPRARRLPEGPDGPAAVIDPARWEWRHDWPGRDLPGAVLYELHTGTF
                     TREGTFDAAARRLPHLAALGITHIELMPVCPFPGRHGWGYDGVAPWAVHEPYGGPDGLR
                     RFVDAAHGHGLGVVLDVVHNHLGPSGNHLPAYGPYFTDRHQTPWGAAVNLDGPGSAEVR
                     TYLIGSALAWLTDYRLDGLRLDAVHALADDSPRHFLADLSEAVDGLAERLGRPLFLIAE
                     SDRNDPATITPRPSGGLGLHAQWNDDFHHALHTALTGESQGYYADFAADPEYALTKTLR
                     GGFFHDGTHSSFRGRPHGRPLDPAAVPAHRLLGYAQTHDQIGNRALGDRLAARLSPGLL
                     ACAAALVLCAPFTPMLFMGEEWGARTPWQYFTDHTDPELAEAVRRGRRREFAAHGWPAE
                     EIPDPQDPATRLRSCLDWDEPGRAPHAELLAWHRRLIALRHTEPALTAPGWTDTDPAVG
                     PDRCVTFRRGPLLVAANLGRTPAELPVPASARVLAAWRPLPPPERNGLLHLPAESAAVL
                     RVSE"
     gene            complement(7572..8984)
                     /gene="lpdA"
                     /locus_tag="J7W19_RS25165"
                     /old_locus_tag="J7W19_25165"
     CDS             complement(7572..8984)
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175651.1"
                     /locus_tag="J7W19_RS25165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25165"
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_004949356.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.7e-54, bitscore:
                     183.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHETDVIVIGGGTGGYSTALRAAHLGLDVVLAERDLVGGTCLHRG
                     CIPSKAMLHAAELVDGIAEARERWGVRATLESVDWAALTATRDDIVGRNHKGVESHLSQ
                     AGVRVVRGSASLTSARTIRVDSGAEAGTEWRARRGVVLATGSRPRTLPGLEPDGRHVVT
                     SDDALFAPGLPASVLVLGGGAIGVEYASLHRSMGARVTLVEAADRLLPLEDADVSRHLT
                     RGLKKRGIDVQTGARLEDARPFEGGVRATVRTARGEVRELTVHRLLVAVGRVPVTDGLG
                     LAAAGLSTDARGFLAPADWTRLETAVPGVHVVGDLLPPPSLGLAHASFAEGLLVAETLA
                     GRAPRPVDYAAVPRVTYSSPQTASVGLSEEQAVAAGHDVTVNSMPLTGTAKGMVHGQGG
                     MVKAVADRTGRILGVHLVGPHVSEMIAEGQLMVGWDAEAADVAQHIHPHPTLSEAVGEV
                     MLSLAGRGLHQV"
     misc_feature    complement(9007..9021)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.24"
                     /tool="antismash"
     gene            9067..10041
                     /locus_tag="J7W19_RS25170"
                     /old_locus_tag="J7W19_25170"
     CDS             9067..10041
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985410.1"
                     /locus_tag="J7W19_RS25170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25170"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_078588139.1"
                     /transl_table=11
                     /translation="MSLRQMEYLVAVVEERSFTRAAETLNVTQSALSHQIKALEREVGG
                     ALLERLPRGVGLTPMGRAFLPHAELAVRSAGLARRAAKAAAGAEGGELHIATLHALAIG
                     ALPPVLARWRRVFPDVRLHLREYLTTDELRDHVDRGVADIAIGPRPERWAGPVVSLGTE
                     EIMIVVSRDDPLAGRTRPVHLAELADRAWVRCVLEPVIGGRRWLDRECERYGFRPVTAM
                     EVQHASTAVRLAVAGVGILACSVEVARATAGAVAVPVEPAWRQELTAYARVELTGAALR
                     FVEACREDRRATGAPAPHVGGPAAAHPAPRVSGPAVALAAPAR"
     gene            complement(10001..10441)
                     /locus_tag="J7W19_RS25175"
                     /old_locus_tag="J7W19_25175"
     CDS             complement(10001..10441)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604204.1"
                     /locus_tag="J7W19_RS25175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25175"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_004949361.1"
                     /sec_met_domain="PF13471 (E-value: 1e-26, bitscore: 91.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVVPRRAPVRLSPGRRLLALAAVALAGRLARRPPARIRALLTR
                     LARGARPATYAEARAARAAVEAVSLRCASDEGCLPRSLATVLLCRARGQWPAWAVGVRA
                     RPPFGAHAWVEAEGRMVEERADASYFRVLFTVPAPRGRRPVR"
     gene            complement(10438..10695)
                     /locus_tag="J7W19_RS25180"
                     /old_locus_tag="J7W19_25180"
     CDS             complement(10438..10695)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004946593.1"
                     /locus_tag="J7W19_RS25180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25180"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_004949363.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 1.2e-07,
                     bitscore: 30.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5e-24,
                     bitscore: 82.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.2e-14, bitscore: 52.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALHLRPDASTTDTEYGTVLLDEATGRYWQLNATASLALRTLLAG
                     GTVDQAADALTEGYAVDAERARADVERLLTGMRAAKVVRG"
     aSDomain        complement(10444..10692)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_J7W19_RS25180_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.20E-26"
                     /identifier="RREFam002.1"
                     /label="J7W19_RS25180"
                     /locus_tag="J7W19_RS25180"
                     /protein_end="84"
                     /protein_start="1"
                     /score="82.7"
                     /tool="antismash"
                     /translation="ALHLRPDASTTDTEYGTVLLDEATGRYWQLNATASLALRTLLAGG
                     TVDQAADALTEGYAVDAERARADVERLLTGMRAAKVVR"
     aSDomain        complement(10534..10695)
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_J7W19_RS25180_Lasso_Fused_RRE.1"
                     /evalue="5.20E-10"
                     /identifier="RREFam003.1"
                     /label="J7W19_RS25180"
                     /locus_tag="J7W19_RS25180"
                     /protein_end="54"
                     /protein_start="0"
                     /score="30.3"
                     /tool="antismash"
                     /translation="MALHLRPDASTTDTEYGTVLLDEATGRYWQLNATASLALRTLLAG
                     GTVDQAADA"
     gene            complement(10744..12546)
                     /locus_tag="J7W19_RS25185"
                     /old_locus_tag="J7W19_25185"
     CDS             complement(10744..12546)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="J7W19_RS25185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25185"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_051072671.1"
                     /sec_met_domain="Asn_synthase (E-value: 3.9e-35, bitscore:
                     120.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGQEERFFVVLPDHETAAAAAGRLPPGHTRIMTHPSGRPWVVGR
                     TGAEPVVSVEAGTARLVVVGHCSASRSELTALAARTTDPAQLDGPASRWAGSHHLIASV
                     GGRTQIRGSASGLRRVFHGSLDGLAVAGDRADVLAALTGASLDRTVLALRLLGSLPHPL
                     SDRPAWRGVAAVPPGSRLTLSPDGRRHRVDRWWHLPEAVRPLAEAAAPLRRALEEAVRV
                     RTRDSSTLTSDLSGGMDSTTMTVLAAREPVALTAFTVENDDSADDDVYWARLAAARLPG
                     VKHIVFPQRDLPSFFSGLTDLTGPPDEPSTALLSAPRLRALRALAIGHGSRLHLDGLGG
                     DQSLSGHPARYHDLLRSRPLTAARSLYAYRRLAGFPLADAARTLLDGDSYRRWLTAEAA
                     ALVRGRARRARDRAFDWGGELRLPPWATPEARHLVTVALRETVRTAVPLAPARGAHADL
                     LGIQDAGRQVRGFHQLTSTDDILSASPFLDDRVVEACLATRPQDRVTPWEFKPLAKAAM
                     RGITPSEVLERRTKSDGTTIAAEGFAAHRRELAALWDSSRLAALGLADPGPLRALCERP
                     YAPRSHEGAFATALACELWVRSAG"
     gene            complement(12605..12754)
                     /locus_tag="J7W19_RS25190"
                     /old_locus_tag="J7W19_25190"
     CDS             complement(12605..12754)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="J7W19_RS25190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25190"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_106429688.1"
                     /transl_table=11
                     /translation="MKNDEATEPRALAPYEAPQMFEVGSFQEDTGYIGLEGSEPITHSF
                     SKFW"
     misc_feature    complement(12777..12795)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.86"
                     /tool="antismash"
     gene            complement(13065..15440)
                     /gene="treY"
                     /locus_tag="J7W19_RS25195"
                     /old_locus_tag="J7W19_25195"
     CDS             complement(13065..15440)
                     /EC_number="5.4.99.15"
                     /GO_function="GO:0047470 - (1,4)-alpha-D-glucan
                     1-alpha-D-glucosylmutase activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536922.1"
                     /locus_tag="J7W19_RS25195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25195"
                     /product="malto-oligosyltrehalose synthase"
                     /protein_id="WP_004949366.1"
                     /sec_met_domain="Alpha-amylase (E-value: 2.2e-13, bitscore:
                     49.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRDSPAPPTATYRLQLQPSFPFAAAERAVPALAALGVSHLHLSP
                     VLEAVPGSSHGYDVTDHTAVRAELGGEDGLRALSRAARAHGLGLILDIVPNHMAVPAPE
                     HLNGPLWEVLRDGPVSRYARWFDIDWAEHGGRVLLPLLAGRLGDELDRFTVHDGTLRYY
                     DHVLPLRPGTEKLPLPELLDAQWYRPAWWRLARTELNHRRFFTVSELIAVRVEDPEVFD
                     ATHAKVLQLLREEVADGLRIDHPDGLADPAGYLRRLHEATGGRWTVVEKILARDETLPA
                     DWPVAGTTGYDALHRVDGLFTDPAGAERLTAAYRTFAAPPPDRGGDWPATARRAAWRMV
                     SHELVTEVERLVRVAGRICDGALPLRDHAPWALRTALCEILVRLPVYRPYARPGAPVAP
                     ADAALLEEAAREARTAFAVPAEADAVDVVRDAALGRLGDGPDHRDFCARFAQTAAALHA
                     KSVEDTAFYRYAPLLSATEVGGSPGRPAVAPAEFHAFCARSQRDRPTTGTVLSTHDTKR
                     GADVRARIAVLTEYPDAWARLLARLAERTPAPEPHVAWTAWQTAFGLGEPDALRLVPAV
                     LKGVREAALRTTWTEPDAAYEEAVERFVVAGPCGPAHEELTAFAATAAASIRANTLGAA
                     LLHLTMPGVPDVYMGTERVSRTLVDPDNRRPPDFAAGEPAGLGAEKLHLTRTALRLRRA
                     HPAWFGPDATYAPLTAEGPAADHCVAFARSGEVVTVATRLARGLEAAGGWGDTALTLPG
                     DGGGGGGWRELLTGRACDERVLLGRLLHRYPVALLARE"
     misc_feature    15459..15474
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.62"
                     /tool="antismash"
     gene            complement(15480..17606)
                     /gene="glgX"
                     /locus_tag="J7W19_RS25200"
                     /old_locus_tag="J7W19_25200"
     CDS             complement(15480..17606)
                     /GO_function="GO:0004133 - glycogen debranching enzyme
                     activity [Evidence IEA]"
                     /GO_process="GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glgX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118866.1"
                     /locus_tag="J7W19_RS25200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25200"
                     /product="glycogen debranching protein GlgX"
                     /protein_id="WP_004949368.1"
                     /sec_met_domain="CBM_48 (E-value: 4.9e-17, bitscore: 60.6,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 1.5e-15, bitscore:
                     56.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVWPGQAYPLGATYDGAGTNFAVFSEAAERVELCLLHDDGSETA
                     VELRESDAFVRHAYLPGVMPGQRYGFRAHGPYAPERGQRCNSAKLLLDPYARAVSGAVD
                     WCEAVYGYHFDDPDARNDLDSAPHMMTSVVVNPYFDWGDDRPPRTDYHRTVIYEAHVKG
                     LTMLHPELPEDVRGSYAALAHPAIVNHLKDLGVTAIELMPVHQFVNDHRLVDLGLANYW
                     GYNTIGFFAPHNAYASWGDRGQQVLEFKSAVRALHEAGIEVILDVVYNHTAEGNHLGPT
                     LSFRGLDNASYYRLADDPRFYMDTTGTGNSLLMRSPHVLQLIMDSLRYWVTEMRVDGFR
                     FDLAATLARQFHEVDRLSSFFDLVQQDPVVSQVKLIAEPWDVGEGGYQVGNFPPLWTEW
                     NGKFRDTCRDLWRGEPATLADFGSRLTGSSDLYQDDGRRPLASVNFVTCHDGFTLHDLV
                     SYNEKHNEANGEDNRDGESHNRSWNCGTEGETEDPAVLALRERQMRNLIATLLLSQGVP
                     MISHGDEFARTQRGNNNAYCQDSELSWVHWPGPDGTAAERARRMLAFTRAMVWLRRDHP
                     VFRRRRFFHGRPEQGTFNELSDIAWFTPEGEEMRDADWQAAYAKSLAVFLNGGAISEPG
                     PRGERVVDDSFLLLFNAHHGPLDFVIPPDHGRLWQVVVDTALPDGVTDDGRKLAAGDRL
                     TLTDRSLAVLQRPL"
     gene            17959..19197
                     /locus_tag="J7W19_RS25205"
                     /old_locus_tag="J7W19_25205"
     CDS             17959..19197
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055576.1"
                     /locus_tag="J7W19_RS25205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25205"
                     /product="SAV2148 family HEPN domain-containing protein"
                     /protein_id="WP_004949370.1"
                     /transl_table=11
                     /translation="MSSGGLELPPADGDAGEEAPGGTPLGAVSLVRPGEIGAELDWDAA
                     AWSEVRTRARRAGRAYIWLNLVEQRLRAVVAAVLRPVYEPVHGEDEWVVAAAGPAGQEW
                     VQRAVAVREVSRRKGYLLDPADDNVLSFLTLPQLRELLVQHWPCFEPYLDDRRELELAL
                     DELEVTRNVVSRNRALSRTVLDQAERASARLLDILGSGPGGHSVDRLPVDAVEDLVGDR
                     YADVVGVHPDRVRLQRQLPVEDLFGSARRLDAVGIGLNLLVQNYSGRRLVRLAEHGCRA
                     RLLFLNPASSAVRRRERELGLKKGEMSRSVEMNIMHMRRVRDRLSDPTAFEIRVFDETP
                     RFTAYLVNGDGPDGLAVVQPYLRKARGMEAPVLVLRGGRRAEVRAQAPDEHGLFDTYRE
                     EFEGVWQDSRPVS"
     gene            19363..20052
                     /locus_tag="J7W19_RS25210"
                     /old_locus_tag="J7W19_25210"
     CDS             19363..20052
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055579.1"
                     /locus_tag="J7W19_RS25210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25210"
                     /product="3'-5' exonuclease"
                     /protein_id="WP_004949372.1"
                     /transl_table=11
                     /translation="MGWHGELLVGFDLETTGTDPAEARIVTAAVVETKAGEPVGRRSWL
                     ADPGVPIPAEAAAIHGITGERAAAEGRPAYEVVAEIGRTLAAHWAAGTPVVVYNAAFDL
                     SLLAAELRRYGLPPLLPEGLGPVVDPLTIDRAVDRYRKGRRTLGAVCAEYGVVLDAAHE
                     AGADALAAVRVARAIAERHPGIAEADLADLHRSQVRWYGEWAAGYQAWLRRQGQEGAVV
                     DGKWPLR"
     gene            complement(20092..20865)
                     /locus_tag="J7W19_RS25215"
                     /old_locus_tag="J7W19_25215"
     CDS             complement(20092..20865)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143410.1"
                     /locus_tag="J7W19_RS25215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25215"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_004949375.1"
                     /transl_table=11
                     /translation="MPGGRLTQQERRQIALGLADGLAYAEIARRLDRPTSTVTREVMRN
                     GGPTAYRADLAHRATEHRARRRGPAAPRAAEAPPQLHGRDAEAVRAYEETFTTVLMASG
                     VPRMMARVLACLTLTDSGSLTAAELVRRLQVSPASVSKAAAFLESQGLIRRERDQGRRE
                     RYTVDDDVWYQSMTASARALAGLVGTAREGVGVLGSDTPAGIRMENIARFLDFVSESTF
                     RAAEQAREVLHTKPRPAREQDLPAEPDDAPGSHSR"
     misc_feature    complement(20973..20986)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.54"
                     /tool="antismash"
     misc_feature    complement(20991..21006)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.79"
                     /tool="antismash"
     misc_feature    complement(20992..21005)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            21096..21767
                     /locus_tag="J7W19_RS25220"
                     /old_locus_tag="J7W19_25220"
     CDS             21096..21767
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957080.1"
                     /locus_tag="J7W19_RS25220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_25220"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_004949377.1"
                     /transl_table=11
                     /translation="MQKFATPAPISAVLAIPAGRVRFIAADRADTVVEVLPADASKARD
                     VKAAERIAVTYDDGVLRITAEPAKSPVLGSSGSAEVTVRLPAGSRVDAKTADGELRGVG
                     RLGDVAFESARGEVKLDEAASARLVLQAGDVTVGRLGGDAEISTRKGDLRVAEAVRGTV
                     VLHTEAGEVSVGAARGVSASLDAGTAYGRIHNALKNSEGADAALRIRATTSYGDITARS
                     V"
ORIGIN
        1 gccgtagcac ggtgtggcga acgcgtggtg gctgtacgag tggttggcga cctcgaagag
       61 cggatcggcg ccgatcgacc gggcctggtc cgggtactgc tcggcccatc tgccggtcat
      121 gaagagcgtg gcgggcactt tgaggcggcg gagggtggcg atgagggcgg ggttgtcgaa
      181 gtgttcgccg cgggcggcgc gggggccttg gtcggacgtc atgtcggcgt cgaaggtgag
      241 ggctatgtgt ttgccgtggt cgcggcggcc gtgtgagaag aggggggctg cgccggcttt
      301 gcctgggggg agcgtcgggg cggatgtggg tgagggtttt gccggtgcgg ctgcggcggc
      361 cggcttgttg ccgggggtgg cggcctgcgt cgtgccttca ccgccgccgc aggcggttgc
      421 gcagcagagg agggccaggg cgggggcgag ggcgcgggat atgcggggca cggtgggacg
      481 ttaccccggt ggggtgtgcc ccggtcccgc cctttcaccg tttcttgcgg gggcaagccc
      541 ccgcaccccc tgaaaccgcg ctccgcgcgg ttgtcctcaa gcgccggacg ggctgattca
      601 gcccgtccgg cgcttgagga cgagcggcga agccgcgaaa ggggggtctg ggggcgcagc
      661 ccccaggaaa cggtgaaagg gcgggaccgg ggcaccccac cccctcagcc gtccgccaag
      721 gacttcgcgt cgcgcgccag cgccgtgagg cgggagatgg cgcggaagta cttcttccgg
      781 tagcccccgg ccagcatctc ctcgctgaag agccggtcga acggccgccc ggacgcgagc
      841 accggtacct cccggtcgta cagccggtcg gcgagcacga cgagtcgcag ggccgtcgac
      901 tggtccggca ccggttcgac gccggtgagg cagaccgcgc ggacgccgtc gcagagggcg
      961 ccgtagcggc tcgggtggac ctgggagagg tgccggagga gggcggggaa gtcgtccagc
     1021 gaggcgccgt ccaccgagta ggccacccgc ttgacggtct cgtcgtcgaa gggggccggt
     1081 gcctcgggga ggccccggtg gcggtagtcc tcgccgtcga tgcgcagggc gcggaagtgg
     1141 gccgagaggc cctggatctc gcggaggaag tcggcggcgg cgaaccggcc ctcgccgagc
     1201 ttgccgggca gcgtgttgga ggtcgcggcg agcgcgacgc cctgttcgac gagcttgccg
     1261 agcagggtgg agacgaggac ggtgtcgccc gggtcgtcca gttcgaactc gtcgatgcag
     1321 agcagctcgt ggccgccgag cgtgcggacg gtctgctgga agccgagggc accgaccagg
     1381 ttcgtcagct cgacgaaggt gccgaacgcc ttccgttccg gggcggccgg tgccgcgtgc
     1441 cagagggagg ccagcaggtg cgtcttgccg acgccgtagc cgccgtcgag gtagacgccg
     1501 cgcggtccgg ccggggcggg cttggcctcc cgccggaacc agcgcttccg gccgctgccg
     1561 gcggccgggg agccgagccc ggccgcgaag ccggacagca cccggacggc ctcggtctgg
     1621 ctgggctggt tcgggtccgg tatgtaggtg tcgaaccgca ccgcgtcgaa gcgcggcggc
     1681 ggcaccatct cggcgaccag gcgctcggcc gggacgtgcg gggtgcgcga ggtgagcgcg
     1741 acgggctgct cgcccgtcgg gcggggttct ggggatgctg cggtggagga cgacacaact
     1801 ctccagggta gttcgccgcc gcgtgcgggg tggccggggg cggagcgagg catgtcacac
     1861 cgggggcggc gaggcgtgtc acactgcggc ccatgcgacg cctgttcccc tcgcccaccg
     1921 cccccgccga cctccaggac cgcgaatggg ggctcgacga actggccgac ctctacgcct
     1981 accccggggc cgtcgcggac gggcgtccct ggctgcgcgc caacatggtc tcgtccctcg
     2041 acggcgccgc ccaccacgag ggccgctcac agccgctgtc ctccgccgcc gacatgcgga
     2101 tcttcggtac gctgcgcgcg ctcgccgacg ccgtcgtggt cggcgccgag accgtacggc
     2161 aggagggcta ccgcccggcg cgcgtccgcg aggcgttcgc cgcccggcgc gccgcgctcg
     2221 gccagtcccc ggcgccggtg atcgcggtgg tgagcgccgg gctcgacctg gacttcgcgc
     2281 tgccgctgtt cgccgagccg ctggtgccga ccctggtgct gaccggcgag gcggcccccg
     2341 ccgagcggcg ggacgcggcc gccgcggcgg gcgtggaggt cgtcgtggcc ggcgagggga
     2401 ggacggtgga cgtggcgcgc gtaccggagc tgctggccgc ccgcgggatg acacggctgc
     2461 tgacggaggg cgggccgcgg ctgctcgggc agttcacggc ggccggggtg ctggacgagc
     2521 tgtgcctctc gctcgccccg atggtcgcgg ccggggtcgc gccgcggatc gccggcgggc
     2581 ccccgctgga ggtgccgcgg cggttcgcgc tggcgtcggt gctggagcag gacgggttcc
     2641 tgttcacccg gtaccggagg gggacgggtg ggccggcggc gggtgccgcg gcggccgggg
     2701 ccggaggaat cggcatctga caatcggcgg aatcccctgt tccgcttatc gtccgacggg
     2761 cagaattgtg tcggacgctc ccccgggggc acgggttcga aacagcgggc tccgagggag
     2821 cacgcgcagg atggtttctg tgtgggcccg gggcccacgg aggagaaggg cgccgaccgt
     2881 gttcacgagc gtattgatga tcgagcagcc gctgtccgcg acggacgtcg acttcgtcac
     2941 cggcctgcac gacgaggaga tgtccttcgt cgtcctgatg cagcccagag gcgccgagga
     3001 ccggctgctg cgcgccatcg acgacgtcgc cctgggcgag ctggaacagg ccgtccacga
     3061 ggcggacgag cccgagggcg aggccgcgct gcggcccgcc gccctcgcgc tggagcactc
     3121 cctgcgcctc ctgcgggggg ccggcagcga ggcggtcggc cagatcatcg acgatcatcc
     3181 gctggacctg ctccgttccg tcgtcgagca gacccacgcc gacgaggtga tcgtgctgac
     3241 cgcaccccac ctcgtcgagg agttcttcca ccgcgactgg gcctcgcgcg cccgccacaa
     3301 ggtcggcgtg ccggtcctca agctgtacgc gcacgccgac gcggacgagg agcggtccgc
     3361 ggccgacgtg gagtagaccc tggacgtcaa acggggccgc ccgcccgcgg ccatccggac
     3421 aggtgagttt gccgccggac gggctgaccc ctcagcccgt gggggggtgc ccgctccggg
     3481 ggacgggggc accccacccg gccggaggcc gccccgcccg caccgggtgc gagaatcggc
     3541 gcagtcagaa gtccccggac ccccggggac ggagcagcag ccgagaacga cccagggagc
     3601 accgcacatg gcaccggccg tccccacgac gatggaccgc ccgcacttca tcggcatcgg
     3661 cggcgccggc atgtcgggca tcgcgaagat cctcgcccag cgcggcgccc gggtggcggg
     3721 cagcgacgcg aaggagtccg cgaccgcggc ggcgctgcgc gccctcggcg tcacggtcca
     3781 catcgggcac gcggccgggc acctcgccga ggacgccagc tgcgtggtcg tctccagcgc
     3841 catccggcag gacaaccccg agctggccgc cgccgccgag cgcggcatcc cggtggtgca
     3901 ccgctcggac gcgctggcgc ggctgatgga cgggctgcgc ccgatcgccg tcgcgggcac
     3961 ccacggcaag acgaccacca cctcgatgct ggcggtggcg ctggacgcgc tcgcgctcga
     4021 cccgtcgtac gccatcggcg gcgacctcca cggccccggc accaacgccc ggcacggcgc
     4081 cggcgagatc ttcgtggcgg aggcggacga gagcgaccgc agcttccaca agtacgcgcc
     4141 cgaggtcgcg atcatcctca acgccgagct ggaccaccac gcgaactacg cctcgatgga
     4201 ggagatccac gagtcgttcg agatcttcgt gggccggatc cgcccgggcg gcacgctcgt
     4261 cgtctccgcc gaccaggagg gcgcccggga gctgacccgc cgcctcgccg ggcgcaccgg
     4321 cgacgtccgg gtcgtcacct acggcgagtc cgaggacgcc gacgtgcgga tcctcgacgt
     4381 caccccgcgc ggcctgacca gcgaggtcac cgtgctcctc gacggccgcg agctgtcctt
     4441 cggcgtctcc gtgcccggcc ggcactacgc gaacaacgcg gtcgccgccc tcgccgccgg
     4501 tgtcgccctc ggcgtccccg ccgacgacct ggccgccgcc ctcggcaagt acaccggtgt
     4561 gggccgccgc ctccagctca agggcgaggc cgccggcgcg caggtcatcg actcgtacgc
     4621 gcaccacccc accgagatga ccgccgacct ggaggccatg cgcggcgccg cggccggctc
     4681 ccgcgtcctg gtggtgttcc agccccacct gttcagccgc acccaggagc tcggcacgga
     4741 gatgggccgg gcgctcgccc tggccgacgc ctccgtcgtc ctcgacatct acccggcccg
     4801 cgaggatccg atccccggcg tcaccagcgc catgatcatc gacgcggccc gtgaggccgg
     4861 tgccgacgtg cgtgccgagc acgacatggc cgccgttccg gacgtcctcg cgggaatggt
     4921 ccgccccggc gatctcgttc tcaccatggg cgcgggggac gtcacggacc tcggtccgcg
     4981 gatcctggcc cgcctggaga gctgaccccc gagaggacgt acggccgatg ccctacgagg
     5041 tcgagaagac ggacgagcag tggcgcgcgg aactgacgcc ggcggagtac caggtgctcc
     5101 gccgcgccgg gacggaaccg gcgttccgcg gcgagtacac ggacaccacc acggccggcg
     5161 tctactcctg ccgcgcctgc ggagccgaac tcttccgctc caccgagaag ttcgcgagcc
     5221 actgcggctg gccgagcttc tacgacccca aggactccga cgccgtcgag ctcctggagg
     5281 accgctcgca cggcatggtc cgcaccgagg tccgctgcgc ccgctgcggc tcccacctgg
     5341 gccacgtctt cgagggcgag ggctacccga cgccgacgga ccagcgctac tgcatcaaca
     5401 gcatcgcgct gcgcctggag cccgcggagg gctgagcccg gccgggaggc cgggacggga
     5461 agcgggccgg ccggatccgg ccgtcggcga cggggggcgc cgacggccgg acggccggcg
     5521 gaccgacgga ggggtggcgg ccgggaccgg tcggccgggc gggtgaggga tggccggccg
     5581 gccccgaccg cgaccaggga cggaatcccc ccggtcggtc gtccaccacc ttgccctgcc
     5641 cgcccgccgg cgcacggggg ccgaacgggc cgttcgggga ccgttcggcc ccggtccgct
     5701 actcgctcac ccgcaggacc gccgccgact ccgccggcag gtggagcagg ccgttccgct
     5761 ccgggggcgg gagggggcgc caggcggcga ggacgcgggc ggacgcgggg acggggagct
     5821 cggccggggt gcggccgagg ttggcggcca cgaggagggg gccgcggcgg aaggtgacgc
     5881 atcggtcggg gccgaccgcc gggtccgtgt cggtccagcc gggggcggtc agggccggtt
     5941 ccgtgtgccg gagggcgatc agccggcggt gccaggccag gagttcggcg tgcggggcgc
     6001 ggcccggctc gtcccagtcg aggcaggagc gcagccgggt ggccgggtcc tgcgggtcgg
     6061 ggatctcctc cgcgggccag ccgtgggcgg cgaactcgcg gcgcctgccg cggcgtacgg
     6121 cctcggccag ctccgggtcg gtgtggtcgg tgaagtactg ccacggcgtc cgggcgcccc
     6181 actcctcgcc catgaagagc atcggcgtga acggcgcgca cagcaccagc gcggcggcgc
     6241 aggcgagcag gccgggggag aggcgggcgg cgaggcggtc gccgagcgca cggttgccga
     6301 tctggtcgtg cgtctgcgcg tagccgagca gccggtgggc ggggacggcc gccgggtcca
     6361 gggggcggcc gtgcgggcgg ccgcggaacg acgagtgggt gccgtcgtgg aagaagccgc
     6421 cgcgcagcgt cttggtgagg gcgtattcgg ggtccgccgc gaagtcggcg tagtagccct
     6481 gggattcacc ggtcagtgcg gtgtgcaggg cgtggtggaa gtcgtcgttc cactgggcgt
     6541 gcaggcccag gccgccggac gggcgcgggg tgatcgtggc ggggtcgttg cggtcggact
     6601 cggcgatgag gaagaggggg cggcccaggc gttcggcgag gccgtcgacg gcctcggaca
     6661 ggtccgcgag gaagtggcgg gggctgtcgt ccgcgagggc gtggacggcg tccaggcgca
     6721 ggccgtcgag acggtagtcc gtcagccagg cgagggcgct gccgatgagg tacgtccgga
     6781 cttcggcgga gccggggccg tccaggttca ccgccgcgcc ccacggggtc tggtggcggt
     6841 ccgtgaagta cgggccgtag gcggggaggt ggttgccgga cgggcccagg tggttgtgca
     6901 ccacgtccag gacgacgccg agaccgtgcc cgtgcgccgc gtcgacgaac cggcgcaggc
     6961 cgtccgggcc gccgtacggc tcgtggacgg cccagggcgc caccccgtcg tacccccagc
     7021 cgtgtcggcc ggggaacggg cagacgggca tcagctcgat gtgggtgatg ccgagcgcgg
     7081 cgaggtgggg gaggcgtcgg gccgccgcgt cgaaggtgcc ttcgcgggtg aacgtgccgg
     7141 tgtgcagctc gtagaggacc gcgccgggga ggtcgcggcc cggccagtcg tgccgccact
     7201 cccagcgcgc cgggtcgatg acggccgccg ggccgtcggg gccttcgggg aggcggcggg
     7261 cccgggggtc ggggcggagg gggccgtcgt ccagggcgaa gcggtagcgg gtgccttcgg
     7321 tgcccggtgc ttcgcgctgc caccagcctt cgtgggcgtg cgtgcggtgc atggggtggg
     7381 tgccgtcgtc cgtgtggagc gtgacgcgtc gcgtgtgcgg ggcccatacc tcgtacagca
     7441 ccggcggctc ctcgggtcgg agtggggttg cccctgcccc gccctttccc gtttctcgcg
     7501 ggggcaagcc cccgcacccc cgtaaccgcg ctccgcgcgg ttgtcctcaa gcgccggacg
     7561 ggctgattgg ctcagacctg gtgcagcccc cgccccgcca gggagagcat cacctcgccc
     7621 accgcctccg acagcgtcgg gtgcggatgg atgtgctggg ccacgtccgc cgcctccgcg
     7681 tcccagccga ccatcagctg gccctcggcg atcatttcgg agacgtgggg gccgacgagg
     7741 tggacaccga ggatgcggcc ggtgcggtcg gcgaccgcct tcaccatgcc gccctggccg
     7801 tggaccatgc ccttggcggt gccggtcagc ggcatggagt tgacggtgac gtcgtggccg
     7861 gcggcgacgg cctgttcctc ggagaggccg acggacgccg tctgcgggct ggagtaggtg
     7921 acgcggggca cggccgcgta gtcgaccggg cggggggcgc ggccggccag ggtctcggcg
     7981 acgagcaggc cctcggcgaa cgaggcgtgg gccaggccga gggagggcgg cggcagcagg
     8041 tcgcccacga cgtggacgcc gggcaccgcc gtctccaggc gcgtccagtc ggccggggcg
     8101 aggaagccgc gggcgtcggt ggacagtccg gccgccgcca ggcccaggcc gtccgtgacc
     8161 ggcacccggc cgacggccac cagcaggcgg tgcacggtca gttcgcggac ctcgccgcgg
     8221 gcggtgcgga cggtggcccg caccccgccc tcgaaggggc gcgcgtcttc caggcgcgcg
     8281 cccgtctgca cgtcgatgcc gcgcttcttc aggccccggg tgaggtgccg gctcacgtcg
     8341 gcgtcctcca gcggaagcag ccggtccgcc gcctccacca gcgtcacgcg ggcgcccatg
     8401 gagcggtgca gcgaggcgta ctcgacgccg atcgcaccgc cgcccagcac caggacggac
     8461 gccgggagcc ccggcgcgaa cagcgcgtcg tcgctggtca ccacgtgccg gccgtccggt
     8521 tccaggcccg ggagggtgcg cgggcgcgac cccgtggcca ggacgacgcc gcgccgggcg
     8581 cgccactccg tacccgcctc ggcgccggag tccacccgga tcgtacgggc ggaggtgagg
     8641 gaggcggagc cgcggacgac gcggacgccc gcctgggaca ggtggctctc gacgcccttg
     8701 tggttgcggc cgacgatgtc gtcgcgggtg gcggtcagcg cggcccagtc gacggactcc
     8761 agtgtggccc gcacgcccca gcgctcgcgc gcctccgcga tgccgtccac cagttccgcc
     8821 gcgtgcagca tcgccttgct cggtatgcag ccccggtgca ggcacgtgcc gccgacgagg
     8881 tcgcgttcgg cgagcaccac gtccagcccg aggtgcgccg cgcgcagtgc ggtgctgtag
     8941 ccgccggtgc cgccgccgat gacgatgacg tctgtctcat gcatggcaca accctccgcc
     9001 cagcagtgaa tatgagtcca acgcaaggtt tcgatcggag cgatgaacga tgttcatggg
     9061 ggagtcgtga gtctgcggca gatggaatat ctggtggcgg tggtcgagga gcggtccttc
     9121 acccgtgccg ccgagacgct caacgtcacc cagtccgccc tgtcccacca gatcaaggcg
     9181 ctcgaacggg aggtgggcgg cgccctgctg gagcggctgc cgcgcggggt cgggctgacg
     9241 cccatgggac gggccttcct gccgcacgcc gaactcgccg tccgcagcgc ggggctggcc
     9301 cggcgggcgg ccaaggcggc ggccggggcc gagggcggcg agctgcacat cgcgacgctg
     9361 cacgcgctgg cgatcggcgc gctgccgccg gtcctcgccc gctggcggcg cgtgttcccc
     9421 gacgtccggc tgcacctgcg cgagtacctg accacggacg agctgcgcga ccacgtggac
     9481 cggggcgtcg ccgacatcgc gatcggcccc cggcccgagc gatgggcggg gccggtggtc
     9541 tccctgggga ccgaggagat catgatcgtc gtctcccggg acgatcccct ggcggggcgt
     9601 acgcgcccgg tccacctcgc cgaactcgcg gaccgggcct gggtgcgctg cgtcctggaa
     9661 ccggtgatcg gcggccggcg gtggctcgac cgcgagtgcg agcggtacgg gttccgcccg
     9721 gtgaccgcca tggaggtgca gcacgcgtcc acggcggtcc ggctggccgt ggcgggcgtc
     9781 ggcatcctcg cctgctcggt ggaggtggcg cgggcgacgg cgggggcggt cgccgttccg
     9841 gtggaaccgg cgtggcggca ggagctcacg gcgtacgcgc gcgtcgaact cacgggcgcc
     9901 gcgctgcggt tcgtcgaggc gtgccgcgag gaccggcggg cgacgggcgc gccggcgccg
     9961 cacgtcggcg gaccggccgc tgcccatccg gcgccgcgcg tcagcggacc ggccgtcgcc
    10021 ctcgcggcgc cggcacggtg aacaggacgc ggaagtacga cgcgtcggcc cgctcctcga
    10081 ccatccggcc ctccgcctcc acccaggcgt gcgcgccgaa cggcgggcgg gcccggacgc
    10141 ccaccgccca ggcgggccac tgaccccgcg cccggcacag cagcaccgtc gccagggagc
    10201 gcgggaggca gccctcatcc gaggcgcagc gcaggctgac cgcctcgacg gccgcccgcg
    10261 cggcgcgcgc ctcggcgtag gtggccgggc gggcgccgcg cgcgaggcgg gtgaggaggg
    10321 cccggatcct ggccgggggc cggcgggcca ggcggccggc gagcgcgacg gcggccaggg
    10381 cgagcagccg ccggccgggg gagagccgta ccggggcccg ccgggggacg accgcgctca
    10441 tccgcggacc accttcgctg cgcgcatgcc ggtcagcagc cgttccacgt cggcgcgggc
    10501 ccgctccgcg tccaccgcgt agccctcggt cagggcgtcc gccgcctggt cgaccgttcc
    10561 gcccgccagg agggtgcgga gcgccagcga cgcggtggcg ttgagctgcc agtagcgtcc
    10621 ggttgcttcg tcgagcagca ccgtgccgta ctcggtgtcg gtggtcgagg cgtcgggacg
    10681 caggtgcagg gccatcgttc gttctctccg tgacggtgtc ggacgcggac agggcggggc
    10741 gggtcagccg gcggaccgca cccacagctc gcaggcgagc gcggtggcga aggccccctc
    10801 gtgcgagcgg ggcgcgtacg ggcgctcgca gagcgcgcgg agcggtccgg ggtcggccag
    10861 gcccagggcg gcgagccggg aggagtccca cagcgcggcg agttcccggc ggtgcgcggc
    10921 gaagccctcg gcggcgatcg tcgtgccgtc cgacttcgtc cgccgctcca gcacttcgga
    10981 gggtgtgatc ccgcgcatcg cggccttggc cagcggcttg aactcccatg gggtgacgcg
    11041 gtcctggggc ctggtggcga ggcacgcctc gaccacccgg tcgtccagga acggcgaggc
    11101 cgacaggatg tcgtcggtgc tcgtgagctg gtggaagcca cggacctgcc gcccggcgtc
    11161 ctggatcccc agcaggtcgg cgtgggcgcc gcgggccggc gcgagcggta cggccgtccg
    11221 gacggtctcc cgcagggcca cggtcaccag gtgccgcgcc tcgggggtgg cccacggggg
    11281 cagccgcagt tcgccgcccc agtcgaaggc ccggtcgcgg gcgcggcggg cgcgaccccg
    11341 gaccagggcg gcggcctccg cggtgagcca gcggcggtag gagtcgccgt ccagcagcgt
    11401 ccgggccgcg tcggccaggg ggaatccggc gagccgccgg taggcgtaca gggaccgggc
    11461 ggcggtcagc ggacggctgc gcagcaggtc gtggtagcgg gccgggtgac cggacaggct
    11521 ctggtccccg ccgagtccgt cgaggtgcag ccgggagccg tgtccgatgg cgagggcgcg
    11581 cagggcccgc agcctggggg cgctcagcag ggcggtggac ggctcgtccg gcgggccggt
    11641 gaggtcggtg agaccgctga agaaggacgg caggtcccgt tgggggaaga cgatgtgctt
    11701 cacccccggc agccgggccg cggccagccg ggcccagtac acgtcgtcgt cggcgctgtc
    11761 gtcgttctcc acggtgaagg cggtcagcgc gacgggctcc cgggcggcca gcacggtcat
    11821 ggtggtggag tccatgccgc cggagaggtc gctggtcagc gtggaggagt cccgggtacg
    11881 gacgcggacc gcctcctcca gggcccgccg cagcggtgct gccgcctccg ccagcggacg
    11941 gaccgcctcc gggaggtgcc accagcggtc gacgcggtgc cgccggccgt cgggggagag
    12001 ggtcagccgg gagccgggcg ggacggcggc cacgccccgc cacgccggac ggtcgctcag
    12061 cgggtgcgga agggagccga gcagacgcag cgccagcacg gtccggtcga gggacgcgcc
    12121 ggtgagggcg gccaggacgt cggcgcggtc gccggcgacg gccaggccgt cgaggctgcc
    12181 gtggaagacg cggcgcaggc cggaggcgct gccccggatc tgggtccggc cgccgacgga
    12241 ggcgatgagg tggtggctgc cggcccagcg ggaggccggc ccgtcgagct gcgccggatc
    12301 ggtggtgcgg gcggcgaggg ccgtcagctc ggaccggctc gccgagcagt ggccgacgac
    12361 gacgagccgc gccgtgcccg cctcgacgga gacgacgggt tcggcgcccg tccggccgac
    12421 cacccagggc cggccggacg ggtgcgtcat gatccgcgta tggcccggag gaagccggcc
    12481 ggcggcggcc gccgccgtct catggtccgg caggaccacg aagaaccgct cttcttgacc
    12541 ggtcacctca acctccatat cgggaccgcc ggatcacgac ggatttaccg gacttcgaac
    12601 gggatcacca gaacttcgag aagctgtgcg tgatcggttc ggagccctcg aggccgatgt
    12661 atccggtgtc ctcctggaaa gagccgacct cgaacatttg cggagcctcg tacggtgcga
    12721 gcgcacgcgg ctcggttgcc tcatcgttct tcatcgcaca ttcaccttct tccttgtgaa
    12781 tacggtggac aaggtggttt cccggcaggg aacggcgcga gtccgctgct catgggcatg
    12841 atcgagcagt gcgtccgcgg tccctccgga aaaccgggtg ttcttccggg aagacgatca
    12901 accgtaacca cggtggatca ccgcgggcaa ccccgaaccg gcccggaaca cgggggagtt
    12961 gcggaatggc gcccactgtt tcccgagatc cgacatttgt cattccgatg aagtgaactc
    13021 cgggaaaatg ccgcgaaatt caggcattac gtcgccggaa cgcctcattc ccgggccagc
    13081 agcgccaccg ggtaccggtg caacaaccgg cccagcagca cccgttcgtc gcacgcccgg
    13141 cccgtcagca gctcccgcca cccaccgcct ccgccgccgt ctcccggcag cgtcagcgcc
    13201 gtgtcgcccc agccgcccgc cgcctccagc ccccgtgcca gccgcgtcgc caccgtcacc
    13261 acctcgcccg agcgggcgaa ggcgacgcag tggtcggcgg cgggcccctc ggcggtcagc
    13321 ggggcgtacg tggcgtccgg gccgaaccag gcggggtggg cgcggcgcag gcgcagcgcg
    13381 gtacgggtga ggtggagctt ctccgccccc aagccggcgg gctccccggc cgcgaagtcc
    13441 ggcgggcggc ggttgtcggg gtcgacgagg gtgcgggaga cgcgttcggt gcccatgtag
    13501 acgtcgggga cgccgggcat ggtgaggtgg agcagtgccg cgccgagcgt gttggcccgg
    13561 atcgacgcgg cggcggtcgc cgcgaaggcg gtgagctcct cgtgggccgg gccgcacggc
    13621 ccggcgacga cgaagcgctc gaccgcctcc tcgtacgccg cgtcgggctc ggtccacgtc
    13681 gtccgcagcg ccgcctcgcg gacgcccttg aggacggcgg ggacgagccg cagggcgtcc
    13741 ggttcgccca ggccgaaggc ggtctgccag gccgtccagg ccacgtgcgg ctcgggcgcg
    13801 ggcgtccgtt ccgccagccg ggcgagcagc cgcgcccacg cgtccgggta ctcggtgagc
    13861 accgctatcc gcgcccggac gtcggcgccg cgcttggtgt cgtgggtgga caggaccgtg
    13921 ccggtggtgg gccggtcgcg ctgcgaacgg gcgcagaagg cgtggaactc ggcgggcgcg
    13981 acggccggcc ggccggggga gccgccgacc tcggtggcgg acagcagggg cgcgtagcgg
    14041 tagaaggcgg tgtcctccac ggacttggcg tgcagggcgg cggcggtctg ggcgaaccgg
    14101 gcgcagaagt cccgatggtc cggcccgtcg ccgagccgtc ccagggccgc gtcccgcacc
    14161 acgtccaccg cgtccgcctc cgccggcacg gcgaacgccg tccgcgcctc ccgcgccgcc
    14221 tcctccagca gggcggcgtc ggcgggggcc acgggtgcgc cgggccgggc gtaggggcgg
    14281 tagacgggca gccggacgag gatctcgcag agggccgtgc gcagcgccca gggggcgtgg
    14341 tcgcgcagcg gcagcgcgcc gtcgcagatc cggccggcga cgcggacgag gcgttcgacc
    14401 tccgtcacca gctcgtggga gaccatccgc caggcggccc ggcgggccgt ggccggccag
    14461 tcgccgccgc ggtcgggcgg cggcgcggcg aacgtccggt aggcggcggt gagccgctcg
    14521 gcgccggccg ggtcggtgaa caggccgtcg acgcggtgga gggcgtcgta gccggtggtg
    14581 ccggccaccg gccagtcggc ggggagcgtc tcgtcgcggg cgaggatctt ctcgacgacc
    14641 gtccagcggc ccccggtggc ctcgtgcagc cgccgcaggt agccggccgg gtcggcgagc
    14701 ccgtccggat ggtcgatccg cagtccgtcg gccacctctt cgcggagcag ctggagcacc
    14761 ttggcgtggg tggcgtcgaa gacctcgggg tcctcgacgc ggacggcgat cagctcggag
    14821 acggtgaaga agcggcggtg gttgagctcg gtgcgggcca gccgccacca ggccggccgg
    14881 taccactggg cgtccagcag ctcgggcagc ggcagcttct cggtgccggg gcgcaggggg
    14941 aggacgtggt cgtagtagcg cagggtgccg tcgtggacgg tgaagcggtc gagttcgtcg
    15001 ccgagccggc cggccagcag gggaagcagc acccggccgc cgtgctcggc ccagtcgatg
    15061 tcgaaccagc gggcgtagcg ggagaccggc ccgtcccgca gcacctccca cagcggcccg
    15121 ttgaggtgct cgggcgcggg gacggccatg tggttgggca cgatgtcgag gatcaggccg
    15181 agcccgtggg cgcgggcggc gcgggacagc gcgcgcagcc cgtcctcgcc gccgagttcg
    15241 gcccggaccg ccgtgtggtc cgtcacgtcg tacccgtgcg aggagccggg gacggcctcc
    15301 aggacggggg agaggtgcag gtgggagacg ccgagggcgg cgagggcggg cacggcccgc
    15361 tcggccgcgg cgaacgggaa ggagggctgg agctggaggc ggtaggtcgc cgtcggaggc
    15421 gccgggctgt cgcgcttcat gggaacatcc gtacccagtc gaagggctgt gtgctcgtcc
    15481 tacagtgggc gttgcaggac ggccaggctc cggtcggtca gggtgagccg gtcgccggcg
    15541 gcgagcttcc ggccgtcgtc cgtcaccccg tccgggagcg cggtgtcgac cacgacctgc
    15601 cagagccgcc cgtggtccgg ggggatgacg aagtccagcg gtccgtggtg ggcgttgaac
    15661 agcagcagga acgagtcgtc gaccacccgt tccccgcgcg ggcccggctc ggagatggcg
    15721 ccgccgttga ggaagaccgc cagggacttg gcgtacgcgg cctgccagtc ggcgtcccgc
    15781 atctcctccc cttccggggt gaaccaggcg atgtcggaca gttcgttgaa ggtgccctgc
    15841 tcggggcggc cgtggaagaa gcggcggcgg cggaagaccg ggtggtcgcg gcggagccag
    15901 accatggcgc gggtgaacgc cagcatccgc cgcgcccgct cggccgccgt gccgtccgga
    15961 cccggccagt gcacccagga cagctcgctg tcctgacagt aggcgttgtt gttgccgcgc
    16021 tgggtgcggg cgaactcgtc gccgtggctg atcatcggca cgccctggct gagcagcagg
    16081 gtggcgatga ggttgcgcat ctgccgctcg cgcagggcga gcaccgccgg gtcctcggtc
    16141 tcgccctcgg tgccgcagtt ccacgaccgg ttgtggctct cgccgtcccg gttgtcctcg
    16201 ccgttggcct cgttgtgctt ctcgttgtac gagaccaggt cgtgcagggt gaagccgtcg
    16261 tggcaggtca cgaagttgac ggaggcgagc gggcggcggc cgtcgtcctg gtagaggtcg
    16321 gaggagccgg tcagccggga tccgaagtcg gccagggtgg ccggctcgcc gcgccacagg
    16381 tcccggcagg tgtcccggaa ctttccgttc cactcggtcc acagcggcgg gaagttcccg
    16441 acctggtagc ccccctcccc gacgtcccac ggctccgcga tcagcttcac ctggctcacc
    16501 accggatcct gctgcaccag gtcgaagaac gacgacaacc ggtccacctc gtggaactgc
    16561 cgggcgagcg tcgccgccag atcgaagcgg aacccgtcca cccgcatctc cgtcacccag
    16621 taccgcagcg agtccatgat gagctggagc acatggggac tgcgcatcag cagtgagttc
    16681 ccggtgccgg tggtgtccat gtagaaccgc gggtcgtccg ccagccggta gtacgaggcg
    16741 ttgtccagac cgcggaacga gagcgtcggc cccaggtggt tcccctcggc cgtgtggttg
    16801 tagacgacgt ccaggatcac ctcgatgccg gcctcgtgca gcgcccgcac cgccgacttg
    16861 aactccagga cctgctgccc ccggtcgccc cacgaggcgt aggcgttgtg cggggcgaag
    16921 aagccgatgg tgttgtaacc ccagtaattg gccaggccga gatccaccag gcggtggtcg
    16981 ttgacgaact ggtgcaccgg catcagctcg atcgccgtca cccccaggtc cttgaggtgg
    17041 ttgacgatcg ccgggtgcgc cagcgccgcg tagctgcccc ggacgtcctc cggcagctcc
    17101 gggtgaagca tcgtcagacc cttgacgtgc gcctcgtaga tgaccgtgcg gtggtagtcg
    17161 gtgcgcggcg gccggtcgtc gccccagtcg aagtacggat tgacgacgac ggacgtcatc
    17221 atgtgcggag cggagtccag atcattgcgg gcgtccggat cgtcgaagtg atagccgtag
    17281 accgcctcac accagtcgac ggcgccgctc accgctcgtg cgtacggatc caggagcagc
    17341 ttggcggagt tgcaccgctg cccccgctcg ggggcgtacg ggccgtgggc ccggaagccg
    17401 taccgctggc ccggcatcac ccccggcaga taggcgtggc gcacgaacgc gtcgctctcc
    17461 cgcagctcga ccgccgtctc cgaaccgtcg tcgtgcagca ggcacaactc gacccgctcc
    17521 gccgcctcgg agaagaccgc gaaattggtg cccgcaccgt cataggtggc accgagggga
    17581 tacgcctgtc ccggccagac ctgcataggc tcgactcttt cgcttctccg ggctctcccg
    17641 ggcaccgttg ccctggaccg tcgagataca gatcttcccc aaaagcggcg cccccaccgc
    17701 tcgccgggcc acgtccaccc gggtgacggg cgggatttcc cctcggaggc ccgccttccg
    17761 caagcgggtt tcggcctttc tccgtgctcc gcgccggata tcactatgaa tcagctcact
    17821 cccgcaccgg tgcccccgga caaccgccac acccggcagg cgagttcacc gggcggccga
    17881 ccggggcgtg tgcgccggct cccgcgggcg cagtagtctg ccttgatcat tgaacggggg
    17941 gcggaaggcg gtggactggt gagctcgggc gggctggagc tgccccctgc ggacggcgac
    18001 gcgggggagg aagcgcccgg cggtacaccc ctcggcgccg tctcgctggt gcgccccggc
    18061 gagatcgggg cggagctgga ctgggacgcc gccgcgtgga gcgaggtgcg cacccgcgcc
    18121 cgccgcgccg gccgcgccta catctggctg aatctggtgg agcagcggct gcgcgccgtc
    18181 gtcgccgccg tgctgcggcc ggtgtacgag ccggtgcacg gcgaggacga gtgggtcgtc
    18241 gccgcggccg gccccgccgg ccaggagtgg gtgcagcggg ccgtcgccgt ccgcgaggtc
    18301 agccgccgca agggctacct cctcgacccc gccgacgaca acgtcctcag cttcctcacc
    18361 ctgccccagc tgcgggagct cctggtccag cactggccgt gcttcgagcc gtacctcgac
    18421 gaccggcgcg agctcgaact ggccctcgac gagctggaag tcacccggaa cgtcgtctcc
    18481 cgcaaccgcg ccctctcccg gaccgtcctc gaccaggcgg aacgggcgtc cgcccggctc
    18541 ctggacatcc tcggcagcgg acccggcggg cactccgtgg accggctgcc cgtcgacgcg
    18601 gtcgaggatc tggtcggcga ccggtacgcg gacgtcgtcg gcgtccaccc ggaccgggtg
    18661 cggctccagc ggcagctgcc cgtcgaggac ctgttcggca gcgcccgccg cctcgacgcg
    18721 gtgggcatcg gcctgaacct gctggtgcag aactactcgg ggcgccggct ggtgcggctc
    18781 gccgagcacg gctgccgggc gcggctcctc ttcctcaacc cggcgagcag cgcggtccgc
    18841 cgccgggagc gcgagctcgg cctgaagaag ggcgagatga gccggtccgt ggagatgaac
    18901 atcatgcaca tgcggcgggt gcgcgaccgg ctgtccgacc cgaccgcgtt cgagatccgc
    18961 gtcttcgacg agaccccgcg cttcacggcc tacctcgtca acggcgacgg gcctgacggg
    19021 ctcgccgtgg tccagcccta tctgcgcaag gcgcgcggga tggaggcgcc ggtgctggtg
    19081 ctgcgcggcg gccggcgcgc cgaggtacgg gcgcaggcac cggacgagca cgggctgttc
    19141 gacacctatc gcgaggagtt cgaaggggtc tggcaggact cgcggccggt ctcctgacgg
    19201 ttcgccgcgc cggggccccg ctgtgcggaa cccctcgcct ggagcctcgc gctcggcgct
    19261 cccttgtccg ccggccggta tgacgcggtc tcagcccgtt gtcagtgcct cgtgcgaggc
    19321 tgttcttcca acggggaaag caccaccgag gggggatgtg ccatgggctg gcacggggag
    19381 ctgctggtcg ggttcgacct ggagacgacg gggacggatc cggcggaggc ccggatcgtc
    19441 acggcggccg tcgtggagac caaggccggt gagccggtgg gccggaggag ctggctcgcc
    19501 gatcccggcg taccgatccc ggccgaggct gccgccatcc acggcatcac cggggaacgg
    19561 gcggcggcgg agggccggcc cgcctacgag gtggtcgcgg agatagggcg gaccctggcc
    19621 gcgcactggg cggcgggcac cccggtcgtc gtctacaacg ccgccttcga cctcagcctg
    19681 ctcgccgccg agctccgccg gtacggcctg ccgccgctgc tgccggaggg cctcggcccg
    19741 gtcgtcgacc ccctcaccat cgaccgcgcc gtcgaccgtt accgcaaggg gcgccgcact
    19801 ctcggcgcgg tctgcgccga gtacggggtc gtcctggacg ccgcccacga ggcgggcgcc
    19861 gacgccctgg cggcggtacg ggtcgcccgc gcgatagccg agcggcaccc gggcatagcg
    19921 gaggccgacc tggcggacct gcaccgcagc caggtgcgct ggtacggcga gtgggccgcg
    19981 ggctaccagg cgtggctgcg gaggcagggg caggaggggg ccgtggtgga cgggaagtgg
    20041 ccgctgcggt agggcggggg agcggggcag cccccgccgg gcggctgccg gctaccggct
    20101 gtggctgccg ggcgcgtcgt cgggctcggc cgggaggtcc tgctcccggg ccggtcgcgg
    20161 cttcgtgtgg agcacctccc gggcctgctc ggcggcgcgg aaggtgctct cggagacgaa
    20221 gtcgaggaag cgcgcgatgt tctccatgcg gatgccggcc ggggtgtcgg agccgaggac
    20281 gccgacgccc tcccgcgcgg tcccgacgag cccggcgagc gcgcgggcgc tggccgtcat
    20341 cgactggtac cagacgtcgt cgtcgacggt gtagcgctcc cggcggccct ggtcgcgctc
    20401 ccggcggatg aggccctggc tctccaggaa cgcggccgcc ttggagacgg aagccgggct
    20461 cacctggagg cggcggacga gttcggcggc ggtgaggctg ccggagtcgg tgagggtgag
    20521 gcaggccagc acccgggcca tcatcctggg tacgcccgac gccatgagga cggtggtgaa
    20581 ggtctcctcg tacgcgcgca cggcctcggc gtcgcgtccg tggagctgcg ggggcgcctc
    20641 cgcggcccgc ggcgcggccg gtccgcgccg ccgggcgcgg tgttcggtgg cacggtgggc
    20701 caggtcggcg cggtaggcgg tggggccgcc gttgcgcatc acctcgcggg tgaccgtcga
    20761 ggtcggacgg tcgagacggc gggcgatctc cgcgtaggcg aggccgtcgg ccaggcccag
    20821 cgcgatctgc cggcgttctt gctgggtgag cctgcctccc ggcatctcgt cctccttcgc
    20881 ggtcctggtc ccggggaagc cgccaccata gcgttcgcct tcatctcatt gcaacgagag
    20941 gagggctgac gttgcgttac ctgtcaggat cgttgcaatg atttaccccg attgacctgc
    21001 gtaaatgagg agttgctgca acaatgtcgt tgtgaggttc gtaaatgcaa cgtagcgttt
    21061 ccttcgtcgg aaagagatcg agcaaggaga ccaccgtgca gaagttcgcc acccccgccc
    21121 ccatctccgc cgtcctcgcc atccccgcgg gccgcgtccg gttcatcgcc gccgaccggg
    21181 ccgacaccgt ggtcgaggtg ctgcccgcgg acgcctccaa ggcccgggac gtcaaggccg
    21241 cggagcggat cgcggtcacc tacgacgacg gagtcctgcg gatcacggcc gagccggcga
    21301 agagcccggt cctgggcagc tccggatcgg ccgaggtgac cgtccgactg cccgccggtt
    21361 cccgggtcga cgccaagacc gccgacggtg aactccgggg cgtcggacgg ctcggcgacg
    21421 tcgccttcga gagcgcgcgg ggcgaggtca agctcgacga ggccgcgagc gcccgcctcg
    21481 tcctccaggc cggtgacgtc acggtcggac gcctgggcgg cgacgcggag atcagcaccc
    21541 ggaagggcga cctccgagtc gccgaggcgg tgcgcggcac ggtcgtgctg cacaccgaag
    21601 ccggcgaggt gtcggtcggc gcggcccgcg gcgtctccgc gtcgctggac gcgggcaccg
    21661 cctacggccg gatccacaac gcgctcaaga acagcgaggg cgcggacgcc gccctgagga
    21721 tccgcgcgac cacctcctac ggtgacatca ccgcgcgcag tgtctgacgc cgtgtccggc
    21781 ggagcgcgcg cctgccgccg gccgtcagaa gggccgccag cgcaccgcgg ggtcgccgtc
    21841 gcgcagcgac gcgaccctgc gccggaactc ggccagcgcg gccggattgc ccggcgcgtg
    21901 ctgggcgacc caggcgcaac tggccgtctc acgcgccccg cgcagcaccg cgcagccgtc
    21961 ccactcgcgg acgtcccagc cgtaggcgcg gacgaaggtg tcgtaggccc gcgggtcgag
    22021 gccgtagcgg tcgcggctga gcgccatcac gaccaggtcg tgctcgcgca ggtcggcggc
    22081 gaaggtctcc aggtcgacca ggacgggccc gtccggcccg acgtggacgt tgcgggggag
    22141 cgcgtcgccg tgcaccgggc ccggcgggag gtgcgggacg agcgcggcgg cggccccggc
    22201 gaaaccgtcg cgccgctcgc gcaggtacgc cgcgtccgcc gggtcgatcg cctcgccggc
    22261 cagcagcagc cagcgctcga caccgtcgag cagttcgcgc ggcggcaggc cgaagtccgg
    22321 ggcgggcagg gcgtggacga gccggaggag cccggccagg tcctcggggg ccgcggggcg
    22381 gacggcgtcg gggaggcggt gccagaacgt caccgggtgc ccgtccgcca gtgccacctc
    22441 cgcctcggcg ggccgcacgg ccgggacgcc gctctccgcc agccacgtgg cgacgcgcag
    22501 ttcacggcgc gcgcggtcgg cgagcgaggc gtgccgcccg accttc
//
