LOCUS       NZ_CP072827            23342 bp    DNA     linear   CON 18-JAN-2024
DEFINITION  Streptomyces mobaraensis NBRC 13819 = DSM 40847 chromosome, complete
            genome.
ACCESSION   NZ_CP072827
VERSION     NZ_CP072827.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces mobaraensis NBRC 13819 = DSM 40847
  ORGANISM  Streptomyces mobaraensis NBRC 13819 = DSM 40847
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7574085)
  AUTHORS   Li,P.
  TITLE     Telomere system of Streptomyces mobaraensis DSM40847 linear
            chromosome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7574085)
  AUTHORS   Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2021) Institution of Microbiology, Jiangxi Academy
            of Science, Changdong Road 7777, Nanchang 330012, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly         :: AORZ00000000
            Genome Coverage                   :: 60.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/18/2024 06:31:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,545
            CDSs (total)                      :: 6,448
            Genes (coding)                    :: 6,310
            CDSs (with protein)               :: 6,310
            Genes (RNA)                       :: 97
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 23 of 138
            Pseudo Genes (incomplete)         :: 120 of 138
            Pseudo Genes (internal stop)      :: 5 of 138
            Pseudo Genes (multiple problems)  :: 9 of 138
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:35:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1251710
            Orig. end                         :: 1275052
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072827.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23342
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="9"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23342
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23342
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13342](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13342
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(685..1452)
                     /locus_tag="J7W19_RS04775"
                     /old_locus_tag="J7W19_04775"
     CDS             complement(685..1452)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS04775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J7W19_04775"
                     /product="hypothetical protein"
                     /protein_id="WP_004952262.1"
                     /transl_table=11
                     /translation="MRKLVGRSAAAAVLAAGVIVPAAGVAVAAPQSSSTPKVASWDDDH
                     GRDHGRDRDRDRDRDKGRDKHRDRDRRDRDRDRDCDRGRHHRDRDRDCDRGRWDRDRDC
                     DHGRWGRHHDDDCDRGRHHGGWGNGWGNINIWGGWGNWGGGHHKGGWDRDCDRGGWGHN
                     GGWGHEGGWGHNGGWGHRGGGWDRDCDRGDWGRGGGWGHHSGWGWGRGDDCDNGWKHRG
                     RDRDCDWNDGWGHKGGHGGKYVRNTVNILGISL"
     gene            1732..3141
                     /locus_tag="J7W19_RS04780"
                     /old_locus_tag="J7W19_04780"
     CDS             1732..3141
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003958062.1"
                     /locus_tag="J7W19_RS04780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04780"
                     /product="solute carrier family 23 protein"
                     /protein_id="WP_004952265.1"
                     /transl_table=11
                     /translation="MGLGVRWTLHGDGRTPAPGAVVAPDERLSWPRTAGLGAQHVVAMF
                     GASFVSPVLMGLDPNLAIMMSGVATMLFLLATRGRIPSYLGCSLSFVGVAAVIRAQGGD
                     SAAVTGAIFVVGAALFLSGLAVRRFGARIIHAAMPPVVTGAVVMLIGFNLAPVTASTYW
                     PQDQWTALLTMLFTGLAVVCLRGFWSRVAIFLGLLFGYALSWTLDRIFGKIHSVNGGPQ
                     AVDHWRLDLSGVGKADWIGLPSLHGPSFGWSAALVALPVVIALIAENAGHVKAVGEMTG
                     DPLDDRLGTAISADGAATMLSTAVGGPANTTYSENIGVMAATRVYSTAAYWAAACFALL
                     FGICPKFGAVVAAVPGGVLGGITVILYGMIGLLGAQIWVHNKVDLRNPLNLVPIAAGVI
                     IGVGGVSLKISNNFELNGIALGTIVVLTGYHALRFLAPPHLKRQEPLLDEGTSGYDGLA
                     AEGERDGRSGA"
     misc_feature    3166..3179
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.61"
                     /tool="antismash"
     misc_feature    3230..3243
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            3250..>3933
                     /locus_tag="J7W19_RS04785"
                     /old_locus_tag="J7W19_04785"
                     /pseudo=""
     CDS             3250..>3933
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056289.1"
                     /locus_tag="J7W19_RS04785"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04785"
                     /product="DUF5995 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTRARTMTPMTGIERVVARMRALAAELPPEDGVAVFNGVYLAVTE
                     EVARRVPDGGFRDRLATTTLDVLFASRYLDAVDEAAAGRRPPACWRPLFQLRGHPAVRP
                     VQFALAGINAHIGHDLPLALADTCRGLGAEPRDLEGDFHRVGALLVSVEERIREALMPG
                     PDLLDVADPLTHLLGSWTLEAARGAAWAAFRALWALRERPEVAAEFAERVDASVGLVGR
                     CLLTPL"
     gene            complement(4080..5789)
                     /locus_tag="J7W19_RS04790"
                     /old_locus_tag="J7W19_04790"
     CDS             complement(4080..5789)
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671499.1"
                     /locus_tag="J7W19_RS04790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04790"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_004952269.1"
                     /transl_table=11
                     /translation="MTSTVPTAVHDEQVQQNEPPITMFGPDFPFAYDDYLTHPAGLGQI
                     PATEHGAEVAVIGGGLSGIVAAYELMKMGLKPVVYEADQIGGRLRTVGFDGCTEGQDAG
                     LTAEMGAMRFPPSSTAFQHYIDLVGLETKPFPNPLAPCTPSTVVDLKGESHYAETVDDL
                     PQVYRDVAAAWAACLEEGADFSDMNRAMRERDVPRIREIWAKLVEKLDNQTFYGFLCES
                     EAFKSFRHREIFGQVGFGTGGWDTDFPNSILEILRVVYTEADDHHRGIVGGSQQLPLRL
                     WEREPEKIVHWPQGTSLSSLHDGAPRPAVTRLHRTAGNRITVTDAAGDIRTYRAAIFTA
                     QSWMLLSKIECDDALLPIDHWTAVERTHYMESSKLFVPVDRPFWLDKDASGRDVMSMTL
                     TDRMTRGTYLLDDGPDKPAVICLSYTWCDDSLKWLPLSANERLEVMLKSLGEIYPGVDI
                     RKHIIGNPVTISWENEPYFMGAFKANLPGHYRYQRRLFTHFMQDRLPEGKRGIFLAGDD
                     ISWTAGWAEGAVQTALNAVWGVMHQFGGATDPTNPGPGDVYDEIAPVELPED"
     gene            complement(5854..6654)
                     /locus_tag="J7W19_RS04795"
                     /old_locus_tag="J7W19_04795"
     CDS             complement(5854..6654)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157405.1"
                     /locus_tag="J7W19_RS04795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04795"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_004952271.1"
                     /transl_table=11
                     /translation="MNPLRIALFQGPCGVPSSADAALGALDAAARRAAESGARLLLTNE
                     LYLTGYALGDLVPDRAEPADGPGAEAVAAIAARHGLAIGYGYPERDGAAVYNALQLMGP
                     QGTPLAHYRKTHLFGAYETTYFTPGTEAVVQAELDGVRLGLLICYDVEFPEPVRAHALA
                     GTELLLAPTALMRPYEIVPQTIVPARAWESQLYIAYVNRCGTEGEFAFAGLSCLAAPDG
                     TVRARAGADEDLLVAEADPALLHRSRAENTYLADRRPELYTRLV"
     CDS             6655..6825
                     /gene="allorf_1258365_1258535"
                     /locus_tag="allorf_1258365_1258535"
                     /protein_id="allorf_1258365_1258535"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSSSGGRREGVSMNFRRDSGQDSVKRLDGTARPQGATSYGCCVQT
                     SDSLRLFRRRR"
     CDS_motif       6655..6777
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSSSGGRREGVSMNFRRDSGQDSVKRLDGTARPQGATSYGC"
                     /locus_tag="allorf_1258365_1258535_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6778..6825
                     /prepeptide="core"
                     /locus_tag="allorf_1258365_1258535_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="1839.1"
                     /monoisotopic_mass="1838.0"
                     /core_sequence="CVQTSDSLRLFRRRR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSSSGGRREGVSMNFRRDSGQDSVKRLDGTARPQGATSYGC
                     "
                     /leader_location="[6654:6777](+)"
                     /alternative_weights="1857.1"
                     /alternative_weights="1875.2"
     misc_feature    6985..6999
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            complement(7041..7451)
                     /locus_tag="J7W19_RS04800"
                     /old_locus_tag="J7W19_04800"
     CDS             complement(7041..7451)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979157.1"
                     /locus_tag="J7W19_RS04800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04800"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_233478068.1"
                     /transl_table=11
                     /translation="MLIGLGRFVQDAAHHVLSARDGYSLRMMGALGHLAREPGLSYSEL
                     GRRAGVTAQSMQATVLRLEEAGAVARTTPAGRGRKAELQVTERGRRMLDDMRQVLAGLE
                     GPLTAGLSAEERSVLARVLGRVMGNAAAAAGR"
     misc_feature    7435..7448
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            7831..8316
                     /locus_tag="J7W19_RS04805"
                     /old_locus_tag="J7W19_04805"
     CDS             7831..8316
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672964.1"
                     /locus_tag="J7W19_RS04805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04805"
                     /product="DUF2269 family protein"
                     /protein_id="WP_004952276.1"
                     /transl_table=11
                     /translation="MTKLLLSLHVLAAILLIGPATVAASLFPRFARQALAPDGDRTKKG
                     TAALRILHRITRVYSAISVTVPAFGMATAQRMGVLGDTWLVVSMALTAVAAVLLAIAVF
                     SQDAIIDALDLHDTEPEAAPKLAAGLPRLSMITGLFALTWAVVTVLMIVRPGSTTGA"
     CDS             complement(8570..8686)
                     /gene="allorf_1260280_1260396"
                     /locus_tag="allorf_1260280_1260396"
                     /protein_id="allorf_1260280_1260396"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGHDQGFGWFPVDRELAEDTASGDQGDVLPVMVFSDCP"
     CDS_motif       complement(8621..8686)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGHDQGFGWFPVDRELAEDTAS"
                     /locus_tag="allorf_1260280_1260396_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(8570..8620)
                     /prepeptide="core"
                     /locus_tag="allorf_1260280_1260396_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="1660.9"
                     /monoisotopic_mass="1659.7"
                     /core_sequence="GDQGDVLPVMVFSDCP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGHDQGFGWFPVDRELAEDTAS"
                     /leader_location="[8620:8686](-)"
     gene            8678..9457
                     /locus_tag="J7W19_RS33600"
     CDS             8678..9457
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS33600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_004952277.1"
                     /transl_table=11
                     /translation="MTHDFGGAVALRAHLLHGARYRALALVDPAALAPWDSPFFRLAGE
                     HSPVLEQLPPAPHAALVRAHIGTTGGPDPHPAVPERLVEPWLGTAGRPTSHRRIPQADQ
                     WHTDKIQGRYSVMVCWGTDDTWIPPEKGREPAAAIPGASFEPVPGKDRLAEADAPAQLI
                     AARHEFLQSATVSRPWDSDAQWPKSAPAPATRGASVPNEHHWDDASAAPSLLRGKPPLT
                     RGTMRGTRGDHIHLRQSLPDTRSATVSPPDGAARPVA"
     misc_feature    9320..9322
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9696..9711)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.7"
                     /tool="antismash"
     gene            9709..9894
                     /locus_tag="J7W19_RS04815"
                     /old_locus_tag="J7W19_04815"
     CDS             9709..9894
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03898.1"
                     /locus_tag="J7W19_RS04815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04815"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_004952279.1"
                     /transl_table=11
                     /translation="MNTVQAWKDCAYRETLAAAPAHPAGSIDLTEELPGERGGVQAMSG
                     TIAIKTMSAPFWTCCK"
     CDS_motif       9709..9837
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNTVQAWKDCAYRETLAAAPAHPAGSIDLTEELPGERGGVQAM"
                     /locus_tag="J7W19_RS04815_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9838..9894
                     /prepeptide="core"
                     /locus_tag="J7W19_RS04815_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.30"
                     /molecular_weight="1855.2"
                     /monoisotopic_mass="1853.9"
                     /core_sequence="SGTIAIKTMSAPFWTCCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNTVQAWKDCAYRETLAAAPAHPAGSIDLTEELPGERGGVQ
                     AM"
                     /leader_location="[9708:9837](+)"
                     /alternative_weights="1873.2"
                     /alternative_weights="1891.3"
                     /alternative_weights="1909.3"
     gene            10001..13342
                     /locus_tag="J7W19_RS04820"
                     /old_locus_tag="J7W19_04820"
     CDS             10001..13342
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="J7W19_RS04820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04820"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_004948616.1"
                     /sec_met_domain="DUF4135 (E-value: 6.2e-90, bitscore:
                     300.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.5e-46, bitscore:
                     156.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQSTQAPHSAGPGRPSPDRTPPAWVRALRLGERLTDGGPPPCEP
                     SERARERLAAWRRLAAFRDDDRFAENVRTLGTDPGTLLRLLDEPPEELATRIPRPSWAT
                     EDTDAPEPATPTRTPTPTPPTDPVFLPLVAPAIRRAESALLSRLNRLGADAPAGLADAL
                     LATLPLDRLDMVLGPTLVLEVNVARVEGRLRGDTPEERFASFAGLLADPDHQARFRAEY
                     PVLVRQAAEVLDRWSAACARLARHLRDDLPDLRRDLLAGRPADTVRSVALGEGDLHHGG
                     RSVARVEFACGGVVMYKPRSLAVDAAFGALAERFSHDTGLVLRAARVLDRKEHGWAEYI
                     RPAPCSAPDGPALFYRRTGALLALVHALRGSDLYYENVIAAGDHPVLIDLEALFHPGDG
                     SAPVWSASSPADADPAGELLHRSVLATGLLPGRRLVGPPDGRAPAHHAPARRPQTHRPQ
                     TDAPQAADHPQATALPRTTDLSGIGGSAGQPWLTPVPVPVGAGTDEVRLLPREVEVPGA
                     DNRPSLPDGSSVDPGRHLPDLLAGFRTGYDWLTEHRAALLAPGGPVDAFADAPVRYLHR
                     DTYVYDKLLRESFHPDFARDALDRERSLARLCSGWAGAPDRKRIVRDELDALLTGDIPL
                     FRVVPGRRDLLLSTGGTVPGFLARDGLSAVREGLAALGPEDRDRQEWIITTSFTDTLNK
                     AGTPHTKPPHVPRPSSPGRPADTRALTAAAEEIGDRLLRLAVTEGDAVGWLGTRSPGPG
                     VTEIVPLGPDLYGGLAGIGLFLLRLAQVTGARRFRDQADRVADEVARRVTGGEHPDAGA
                     LYLMSHDLKAGGPADRFRAVRDAVLPALRTAVAEDTAYDVIDGAAGYVLMCLAAYAADG
                     GPESLEVARLAADHLAARAEPAGAGLGWRHAGIPAPGPLTGLAHGTSGAVVALSRLNAL
                     HPDGRYGALIDGALAYEAGVFEPDAGNWPDLREHAPVRHWSAWCHGAAGVGLARAELLM
                     SPARPAARADRAADELRTALGPTLADRDNHSLCHGGLGNLELLLYAERLGLARPGGLAD
                     RLSAVLERARRTGWRSGAPAGEEVPGLFTGLAGIGHNLLRFAAPDDVPSVLLLEPPPGI
                     RTAPPS"
     gene            complement(13320..13775)
                     /locus_tag="J7W19_RS04825"
                     /old_locus_tag="J7W19_04825"
     CDS             complement(13320..13775)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645535.1"
                     /locus_tag="J7W19_RS04825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04825"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_004948618.1"
                     /transl_table=11
                     /translation="MRLNELDERIVHALAEDARRSYADIGAEVGLSAPAVKRRVDRLRA
                     EGAITGFTVRVDPGALGWETEGFIELYCRRNTSPEAIHRGLSRYPEVASASTVTGEADA
                     IVQIFASDMRHFERVLERIAGEPFVERTKSVLVLSPLLRRFSSGAPS"
     gene            complement(13865..15430)
                     /locus_tag="J7W19_RS04830"
                     /old_locus_tag="J7W19_04830"
     CDS             complement(13865..15430)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534802.1"
                     /locus_tag="J7W19_RS04830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04830"
                     /product="amino acid permease"
                     /protein_id="WP_004948621.1"
                     /transl_table=11
                     /translation="MLDQDTAPPAAGNGKRPPQPPAGTGSRLMRRKPVERLVAEGGQGE
                     GGTLRRSLGMWQLTMISIGATLGTGIFVVLGTAVPDAGPAVVISFVLAGLTALFSALSY
                     AELAGTIPVSGSSYSYSYATLGEIVAWICGWCLILEYGVSVAAVAVGWGQYLNELLDGT
                     IGVTIPASLANPPGDGGIFNVPALLVVLLCMAFLLGGAKESARANAIMVGVKIAALLLF
                     CAVAFTGIKAGNYSPFMPLGLAGVSNAGASLFFSYIGFDAASTAGEEAKNPKKDLPKAI
                     MLSLLIVTALYVLVAAIAVGALPWKQFEGSEAALAGIMKDVTGQSFWAVLLAAGAVIAI
                     ASVVLTVLYGQTRILFAMARDGLVPKTFAKVSPRKGVPVANTIITCAFCGVLAAAVPLA
                     ELADATSIGTLFAFALVNVAVIVLAVKRPDMKRSFTVPLSGVRVPLFGGLRVRLGMIFP
                     VIGFGLCFYLMYKLPTVTWEVFGLWMAVGFVIYFAYGMRHSRLNGGTDDGSAEADASEA
                     PAKG"
     misc_feature    complement(15411..15429)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.14"
                     /tool="antismash"
     misc_feature    complement(15598..15614)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.01"
                     /tool="antismash"
     misc_feature    complement(15611..15624)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.25"
                     /tool="antismash"
     gene            complement(15780..17222)
                     /locus_tag="J7W19_RS04835"
                     /old_locus_tag="J7W19_04835"
     CDS             complement(15780..17222)
                     /GO_function="GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564159.1"
                     /locus_tag="J7W19_RS04835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04835"
                     /product="GuaB1 family IMP dehydrogenase-related protein"
                     /protein_id="WP_004948626.1"
                     /transl_table=11
                     /translation="MRFLNDQKPPYDLTYDDVFMVPSRSAVGSRQGVDLSAPDGTGTTI
                     PLVVANMTAIAGRRMAETVARRGGLVVIPQDIPIEVVTDVITWVKSRHHVLDTPIVLAP
                     TQTVADALSLLPKRAHGAGVVVDGDHRPVGVVTEHDLTGVDRFTQLSEVMSKELLLLDA
                     DIDPREAFNQLDAAHRKLAPAVDKDGKLAGILTRKGALRATLYTPATDADGKLRVAAAV
                     GINGDVAGKAKALLDAGADTIVVDTAHGHQESMIAAIKAVRALDPRVPIVAGNIVAAEG
                     VRDLVEAGADIIKVGVGPGAMCTTRMMTGVGRPQFSAVLECAAEAKKYGKHVWADGGVR
                     HPRDVAMALAAGASNVMIGSWFAGTYESPGDLQQSADGRLYKESFGMASARAVRNRTSE
                     ESAYDRARKGLFEEGISTSRMFLDPARPGVEDLIDSIIAGVRSSCTYAGAGNLAEFHER
                     AVVGVQSAAGYAEGKPLHASWQ"
     misc_feature    complement(17240..17256)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.27"
                     /tool="antismash"
     gene            17460..18011
                     /locus_tag="J7W19_RS04840"
                     /old_locus_tag="J7W19_04840"
     CDS             17460..18011
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126388.1"
                     /locus_tag="J7W19_RS04840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04840"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_004948628.1"
                     /transl_table=11
                     /translation="MTHQEIICRPSGPEDDAAVAALDGSFTTDTVYAVTPFPGSAEGFA
                     LRPVPVDPPVRKVFPDDEPDGEEAGDGARRYAAFAGDELCGFVATSYEPWNRRLTVEDI
                     EVAPAYRGRGVGRALMECVAEQARECGAGHVWLEVTNINAPAIRSYLRMGFSFCGMDTT
                     LYSGTASEGEIALFMSRSCS"
     gene            complement(17951..19618)
                     /locus_tag="J7W19_RS04845"
                     /old_locus_tag="J7W19_04845"
     CDS             complement(17951..19618)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129660.1"
                     /locus_tag="J7W19_RS04845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04845"
                     /product="MFS transporter"
                     /protein_id="WP_004948630.1"
                     /transl_table=11
                     /translation="MPDDIGRRRRVLVLLICCTSLLLVSLDGSAVNIALPALSTELHAS
                     MAGLQWIVDSYLLVLASLLMLAGSTADRIGRRRTFTAGLVVFTTGSLLCGFAPGLGWLV
                     AFRVVQAIGGSMLNPVAMAIITNTFTDRAERARAIGVWGGVLGISMALGPVVGGALVDS
                     VGWRAIFWINVPIGIAAVVLCRRFVPESKAARVRRFDPVGQLLVVVLLASLVYAVITGR
                     ERGWASAPIVALFALAAVVLVVLVGYERRRAEPLIEPRYFRSVPFSGASVIGFCGVGAL
                     GGFLFVEPLYLQGVRGLSAVDAGLYTLPLAAMMLVAGPVSGRLVAARGPRLPLVVAGTA
                     ITLAALGLTRVDADTPTAWLLADHALFGLGFGLMNPPITTTAVTGMPAERAGTAAGMMS
                     TARQVGQASGVAVIGTVVSAHLDGPVRTHFAAASHGGWWIVTACGLVVAVLGAATTGPR
                     ARRTAVAAAAALTGEPAPERAGAGPVAGPVAGEAAGAGGGPGSGPAHAAGGGPAQAPES
                     GPAQASGNGPAQASGSGSDQEQERLMKSAISPSDAVPE"
     CDS             complement(19733..19873)
                     /gene="allorf_1271443_1271583"
                     /locus_tag="allorf_1271443_1271583"
                     /protein_id="allorf_1271443_1271583"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAVAARALGAYPRRGGPEHPSLRVGGALASYECRNRLCSHAGNAG
                     F"
     CDS_motif       complement(19844..19873)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAVAARALGA"
                     /locus_tag="allorf_1271443_1271583_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19733..19843)
                     /prepeptide="core"
                     /locus_tag="allorf_1271443_1271583_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="3803.2"
                     /monoisotopic_mass="3800.9"
                     /core_sequence="YPRRGGPEHPSLRVGGALASYECRNRLCSHAGNAGF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAVAARALGA"
                     /leader_location="[19843:19873](-)"
                     /alternative_weights="3821.2"
     gene            complement(20039..20173)
                     /locus_tag="J7W19_RS33385"
     CDS             complement(20039..20173)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J7W19_RS33385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_267939118.1"
                     /transl_table=11
                     /translation="MPRLGEVDRWQGERQLPDGRAERLDGGMTETKLRDPLRSGGVAA"
     gene            complement(20252..21238)
                     /locus_tag="J7W19_RS04850"
                     /old_locus_tag="J7W19_04850"
     CDS             complement(20252..21238)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982703.1"
                     /locus_tag="J7W19_RS04850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04850"
                     /product="sugar-binding domain-containing protein"
                     /protein_id="WP_004948633.1"
                     /transl_table=11
                     /translation="MGPAELVQAAAMARRFYLEGKSKIQIAEEFGVSRFKVARVLETAL
                     ERDLVRIEIRVPAELDAERSDALRARYGLRHAVVVESPADAAEDAPDPENLGEVAAGLL
                     GELVNEGDVLGLAWGRSTIHMAAALHRLPPCTVVQLTGVYDAGTAERGSVEAVRRAAQV
                     SGGEAHPIYAPMLLPDPATAAALRGQTGIARAFEYFDKVTVAAVSIGSWEPGISTVYDM
                     LSDEERTHYASLGAAAEMSAHLFDAEGRRIGRDLGERCITVEADRLRRIPEVVAIAGGA
                     RKAAAIGAVLRSGLVTSLVTDTAAADYLLTESAPGPRPALDRADPDV"
     misc_feature    complement(21318..21327)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            complement(21378..22064)
                     /gene="rpe"
                     /locus_tag="J7W19_RS04855"
                     /old_locus_tag="J7W19_04855"
     CDS             complement(21378..22064)
                     /EC_number="5.1.3.1"
                     /GO_function="GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rpe"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988937.1"
                     /locus_tag="J7W19_RS04855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_04855"
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="WP_004948636.1"
                     /transl_table=11
                     /translation="MTVQINPSILSADFARLADEAQAVKGADWLHVDVMDNHFVPNLTL
                     GVPVVESLSRATSTPLDCHLMIEDPDRWAPQYVEAGAGSVTFHVEAAAAPVRLAREIRA
                     KGARASMALKPATPIEPYEDLLPELDMLLIMTVEPGFGGQKFLDIMLPKIRRTRELISR
                     HGLELWLQVDGGVSAETIERCAEAGADVFVAGSAVYGTDDPAAAVRSLRELAETATSAA
                     PWACGH"
ORIGIN
        1 cggtgttcgc cgagggggcg agcctggagt ggtcggcggt ctatctgcgg gacgtcgtcg
       61 gctccggggc ggggctggcg gccgcctgca ccacggcctt ctcctgcgcc atggccgcgg
      121 cccggttcgc gggggacgcg gcggtccgcc ggttcgggcc ggtgcgcacg gtccgggcgg
      181 gcggggtgct ggcggcgtgc ggcggtgcgc tggtggtcgg ggcgccgggg gcggggccgg
      241 cgatcgccgg gttcgccttg gtggggctgg gcatcgcggt ggtcgtaccg ctcgccttcg
      301 cggcggccgc acgcagcggg ccggagccga gccaggccat cgcgggggtg gcgacgatca
      361 cgtacacgtc cggtctggtc gccccgtcgg ccatcgggca actcgcggac gccacctcac
      421 tgacggtctc gttcgggctg gtgacggtgc tggcggcgct gctggcggtg acggcggggg
      481 cgctgcggcc ggggatcggc ggcgctgcgc ggggagcggc ggcggagggc ggctgagcgt
      541 cactccttcg agggacgccg ctccttcgag ggacggagcg ccttcgagag acggaacgcc
      601 tccgcgggcc gcgcggccgg ggcttccggt cgcacggccc gcggtggaag gggacctcag
      661 agggtgaacg tcggctcagg atcctcagag gctgatgccc aggatgttga cggtgttgcg
      721 gacgtacttg ccgccgtgac cgcccttgtg accccagccg tcgttccagt cgcagtcgcg
      781 gtcgcgaccg cggtgcttcc agccgttgtc gcagtcgtca ccgcgacccc agccccagcc
      841 gctgtggtgg ccccagccac cgccacggcc ccagtcgccg cggtcgcagt cgcggtccca
      901 gccgccaccg cggtgacccc agccaccgtt gtgaccccag ccaccttcgt ggccccagcc
      961 accgttgtgg ccccagccac cccggtcgca gtcacggtcc cagccgccct tgtggtggcc
     1021 gccaccccag ttgccccagc caccccagat gttgatgttg ccccagccgt taccccagcc
     1081 gccgtggtga cggccgcggt cgcagtcgtc gtcgtggtga cggccccagc ggccgtggtc
     1141 gcagtcacgg tcccggtccc aacgaccgcg gtcgcagtcg cggtcccggt cgcggtggtg
     1201 acggccccgg tcgcagtcac ggtcccggtc gcggtcgcgg cggtcgcggt cgcggtgctt
     1261 gtcgcggccc ttgtcacggt cgcggtcgcg gtcccggtcc cggccgtggt cccggccgtg
     1321 gtcgtcgtcc cagctcgcca ccttgggcgt ggaagacgac tgcggcgcgg cgacggccac
     1381 cccggcggcc ggaacgatga cgcccgcggc gaggaccgcg gcggccgctg agcggccgac
     1441 gagcttacgc atgtatgtct cctggtttgg caggaaatcg gacaacccac gcatacctcg
     1501 cccagggcgg ggacctgccg agcgtcccgg gcatacagcc ttacgaggtg ttaattgcgc
     1561 cgatcgcagc agcgcccgcc cgccccgccg accacccggc ccgcggcacc cccacagcgc
     1621 cccaccggcc gtcaccgacc ggcccgccgc ccgccgttct ccgcacggac cactcctgac
     1681 ccgcgcttaa catggtgcgg atcacctcga acaaccacag tgggagcatt catgggcctc
     1741 ggcgtgcgct ggaccctgca cggcgacggg cgcacccccg cccccggggc cgtggtcgcg
     1801 ccggacgaac ggctctcctg gccgcgcacc gcggggctcg gcgcccagca cgtggtggcg
     1861 atgttcgggg cgtcattcgt cagtccggta ctcatgggcc tggaccccaa cctggcgatc
     1921 atgatgtcgg gcgtcgccac catgctcttc ctgctcgcca cgcgcggccg gatccccagc
     1981 tacctggggt gcagcctgtc gttcgtcggc gtggcggccg tcatccgcgc ccagggcggc
     2041 gacagcgcgg ccgtcaccgg cgcgatcttc gtggtcggcg cggcgctgtt cctcagcggc
     2101 ctggcggtcc gcaggttcgg cgcccggatc atccacgcgg cgatgccgcc cgtggtgacc
     2161 ggcgcggtgg tgatgctgat cggcttcaac ctcgccccgg tgaccgcgag tacctactgg
     2221 ccgcaggacc agtggacggc cctgctcacc atgctcttca ccgggctggc cgtggtctgc
     2281 ctgcgcggct tctggtcgcg tgtcgcgatc ttcctggggc tgctcttcgg ctacgccctc
     2341 tcctggaccc tggaccggat cttcggaaag atccactccg tcaacggcgg cccccaggcc
     2401 gtcgaccact ggcggctcga cctgtcgggc gtcggcaagg cggactggat cggcctcccc
     2461 tccctgcacg gcccgtcgtt cggctggtcg gcggcgctgg tggcactgcc ggtggtcatc
     2521 gccctcatcg cggagaacgc gggacacgtc aaggccgtgg gcgagatgac cggcgacccg
     2581 ctggacgacc gactcggcac cgcgatctcg gccgacggcg cggcgacgat gctgtccacg
     2641 gcggtcggcg ggccggcgaa caccacctac tccgagaaca tcggcgtcat ggcggccacc
     2701 cgcgtctact cgaccgccgc gtactgggcg gcggcctgct tcgcgctcct cttcggcatc
     2761 tgcccgaagt tcggcgcggt cgtcgcggcc gtccccgggg gcgtgctggg cgggatcacc
     2821 gtcatcctct acggcatgat cggcctgctc ggcgcgcaga tctgggtgca caacaaagtg
     2881 gacctgcgca atccgctcaa cctggtgccg atcgcggcgg gcgtgatcat cggcgtcggc
     2941 ggcgtcagcc tcaagatcag caacaacttc gaactcaacg gcatcgccct gggcacgatc
     3001 gtggtcctca ccggctacca cgcgctgcgc ttcctcgccc cgccgcacct caagcggcag
     3061 gagccgctgc tggacgaggg gacgagcggg tacgacggac tggcggcgga gggcgaacgg
     3121 gacggccgct ccggggcctg acggccgcca ccgacctgcg acgtcgtcac tcaccgtcac
     3181 ccgttccggt taacttgaag gccagagccc ctacgctccg tatccatctg tcactctgtg
     3241 tgcatggaga tgacgcgagc acggaccatg acacccatga ccggcatcga gcgggtcgtc
     3301 gcccggatgc gggcgctggc cgccgagttg ccgccggagg acggggtggc ggtcttcaac
     3361 ggggtgtatc tggcggtcac cgaggaggtg gcccggcggg taccggacgg cgggtttcgg
     3421 gaccgtctgg ccaccaccac gctggacgtg ctgttcgcga gccgctatct ggacgcggtc
     3481 gacgaggcgg cggcggggcg aagaccgccg gcctgttggc gtccgctgtt ccagctccgc
     3541 ggccatcccg ccgtccggcc ggtgcagttc gcactggcgg gcatcaacgc ccatatcggc
     3601 cacgacctgc cgctcgccct cgccgacacc tgccgcggcc tgggcgccga accgcgggac
     3661 ctggaggggg acttccaccg ggtcggcgca ctgctggtct ccgtggagga gcggatccgc
     3721 gaggccctga tgcccggccc cgacctgctg gacgtggcgg atccgctcac ccacctgctc
     3781 gggtcgtgga cgctggaggc cgcgcgcggg gccgcgtggg cggcgttccg ggcgctgtgg
     3841 gcactgcgcg aacggccgga ggtggcggcg gagttcgcgg agcgcgtcga cgcgagcgtg
     3901 gggctggtgg ggcgctgtct gctgacgccg ctggggtgcg ggggcggccg ggacgacggg
     3961 aaagacgaga acgacgagaa cgacgagaac gacgggaagc gccccgcgcg ccgggcgggc
     4021 ggcggcgggg cgcttcctcg aagacatccc ttgggacagc ccttgggaca gtccttgtct
     4081 cagtcctccg gcagctcgac gggcgcgatc tcgtcgtaga cgtcgccggg gcccgggttg
     4141 gtcgggtcgg tggcgccgcc gaactggtgc atcacacccc agacggcgtt cagcgcggtc
     4201 tgcacggcac cctcggccca gccggccgtc caggagatgt cgtcgcccgc gaggaagatg
     4261 ccgcgcttgc cctcggggag gcggtcctgc atgaagtggg tgaacagccg gcgctggtag
     4321 cggtagtggc ccgggaggtt ggccttgaac gcgcccatga agtagggctc gttctcccag
     4381 gagatcgtca ccgggttgcc gatgatgtgc ttgcggatgt cgacgccggg atagatctcg
     4441 ccgagcgact tgagcatgac ctccaggcgc tcgttggcgg agagcggcag ccacttgagg
     4501 ctgtcgtcgc accaggtgta ggagaggcag atcacggcgg gcttgtccgg tccgtcgtcc
     4561 aggaggtagg taccgcgcgt catgcggtcg gtgagcgtca tcgacatgac gtcccggccc
     4621 gacgcgtcct tgtccagcca gaacggccgg tccaccggca cgaacagctt ggaggactcc
     4681 atgtagtggg tacgctcgac cgccgtccag tggtcgatcg ggaggagcgc gtcgtcgcac
     4741 tcgatcttgg acagcagcat ccaggactgg gccgtgaaga tggccgcccg gtaggtgcgg
     4801 atgtcgcccg cggcgtcggt gaccgtgatc cggttgccgg ccgtgcggtg cagccgggtc
     4861 acggccgggc ggggcgcgcc gtcgtgcagc gaggagagcg aggtgccctg cggccagtgg
     4921 acgatcttct ccggctcgcg ctcccagagc cgcagcggga gctgctggct gccgccgacg
     4981 atgccgcggt ggtggtcgtc cgcctcggtg tagacgacgc gcaggatctc caggatggag
     5041 ttggggaagt cggtgtccca gccgccggtg ccgaagccga cctggccgaa gatctcccgg
     5101 tggcggaagg acttgaacgc ctccgactcg cagaggaagc cgtagaaggt ctggttgtcg
     5161 agcttctcga cgagcttggc ccagatctcg cggatgcggg gcacgtcgcg ctcgcgcatg
     5221 gcccggttca tgtcggagaa gtccgcgccc tcctccaggc aggcggccca ggcggcggcg
     5281 acgtcgcggt agacctgcgg caggtcgtcg acggtctcgg cgtagtggct ctcgcccttg
     5341 aggtccacga cggtggaggg ggtgcagggg gccagcgggt tggggaacgg cttggtctcc
     5401 aggcccacca ggtcgatgta gtgctggaag gcggtggagg acggggggaa gcgcatggcg
     5461 cccatctcgg cggtcaggcc cgcgtcctgg ccctcggtgc agccgtcgaa gccgaccgtg
     5521 cgcagccggc cgccgatctg gtccgcctcg tagacgacgg gcttgaggcc catcttcatc
     5581 agctcgtagg cggccacgat gccggagagt ccgccgccga tgaccgcgac ctcggcgccg
     5641 tgctcggtgg ccggtatctg gcccagcccg gccgggtggg tcaggtagtc gtcgtaggcg
     5701 aagggaaagt ccgggccgaa catggtgatc ggcggctcgt tctgctggac ctgctcgtcg
     5761 tggacggcgg tgggcaccgt ggacgtcatc ggctgaactc tcctgcgtgc aagggggtgt
     5821 ggggtgaagc gagggggtgg agcgaggggg gactcagacg agccgcgtgt agagctccgg
     5881 cctgcggtcg gccagatagg tgttctcggc gcgcgaccgg tggagcaggg cggggtcggc
     5941 ctcggcgacg agcagatcct cgtcggcgcc ggcccgggcg cgtacggtcc cgtccggggc
     6001 ggcgaggcag gacagcccgg cgaaggcgaa ctcgccttcc gtaccgcacc ggttgacata
     6061 ggcgatgtag agctggctct cccaggcgcg ggccgggacg atcgtctgcg gcacgatctc
     6121 gtagggccgc atcagcgcgg tcggcgcgag cagcagctcc gtgccggcga gggcgtgcgc
     6181 ccgcacgggc tccgggaact cgacgtcgta gcagatcagc agccccagtc ggacgccgtc
     6241 gagctcggcc tgcaccacgg cctccgtacc gggggtgaag tacgtggtct cgtaggcgcc
     6301 gaagaggtgg gtcttgcggt agtgggcgag cggggtgccc tgcgggccca tgagttggag
     6361 cgcgttgtag acggcggcgc cgtcgcgctc cgggtagccg tacccgatgg cgagcccgtg
     6421 ccgggcggcg atcgcggcca cggcttcggc gccgggaccg tcggcgggtt cggcgcggtc
     6481 ggggaccagg tcgccgagcg cgtagccggt caggtagagc tcgttggtga gcagcagccg
     6541 ggcaccggac tccgccgcgc ggcgggccgc ggcgtccagc gcgccgaggg cggcgtccgc
     6601 cgaggacgga acgccgcagg gcccttggaa cagcgcgata cgcagcgggt tcatatgtcc
     6661 tcttcgggtg ggcggcgtga aggcgtttcg atgaactttc gacgggattc cggtcaggat
     6721 tccgttaaac gccttgacgg tacggcccgg cctcaggggg cgacaagcta tggatgttgc
     6781 gtgcagacca gcgattcgtt gcgccttttc cggcgtcgtc ggtgattcgt tgcgcgccct
     6841 gcggcgcccg cgcgcggcac ggcctcatcg ggccccgggc cacgccttcg gggcgcctcc
     6901 ggggccggcc cggacggtgg ggcgggtcgg gcggccgggg acggagggga cggagacgcc
     6961 ctgcgggccg gcggaccgac ggaagggccg accggcgccc ggtctcgggg cgctctgccg
     7021 atccggccgc cggtgatcgt tcagcgaccc gccgccgcgg cggcgttgcc catcacccgc
     7081 cccagcaccc gcgccagcac ggaccgctcc tcggcggaca ggccggccgt cagcgggccc
     7141 tccagtccgg cgagcacctg ccgcatgtcg tcgagcatcc gccggccccg ctcggtgacc
     7201 tggagttccg ccttccgccc ccgcccggcg ggcgtcgtgc gcgcgacggc gccggcctcc
     7261 tccagacgga gaaccgtggc ctgcatgctc tgcgccgtga ctccggcgcg ccgccccagt
     7321 tcgctgtagg agagaccggg ctcccgcgcg agatgcccca gggcacccat catccggagc
     7381 gagtacccgt cccgggcgga cagcacatga tgagccgcat cctgaacgaa ccgcccgagc
     7441 ccgatcaaca tcaacgacaa cggcatcccc ggagaacccc ccgcgggcgg ccctccggca
     7501 ggcggacccc cagcgggcgg acccgcagca ggcgcaccgc ccgcaggcgg accgctcgcg
     7561 gcggcggttt cggcgggccg gcgtccctcc gacgcggacg gtacgtccgc tgcggatccg
     7621 ggccccgtgc ggaacgcttt cgtccgctcg tccccggcca tcaccatcac ccctcgcccg
     7681 cattacgtcc gcttgaccgc cggccatcac acccggggcc acttccggcc acgccgccca
     7741 gggatgctag cgtctcacga tgtttaagcc agactgaaac cctcggccgg cccggttctg
     7801 cccgcccgac cgcgatggga gcggaaagcc atgacgaaac tcctgctcag cctgcatgtg
     7861 ctggcagcga tcctgctcat aggtccggcg accgtggccg ccagcctctt cccccgcttc
     7921 gcgcggcagg ccctggcccc ggacggcgac cgcaccaaga agggcaccgc ggccctgcgg
     7981 atcctccacc gcatcacccg tgtctactcg gcgatctcgg tgaccgttcc cgccttcggc
     8041 atggcgacgg cgcagcggat gggcgtcctg ggcgacacct ggctggtcgt ctcgatggcg
     8101 ctgaccgcgg tggcggcggt gctgctggcg atcgcggtgt tcagccagga cgcgatcatc
     8161 gacgccctcg acctccacga caccgagccc gaggcggccc ccaagctcgc cgccggcctg
     8221 ccccgactgt cgatgatcac cggactgttc gccctgacct gggcggtcgt caccgtcctg
     8281 atgatcgtcc gccccggttc gacgaccgga gcctgaaccg gtcacgagcg atcggttcct
     8341 cgcgtccgcg cccccggccg aggcgaatct ccctgcggga catggcggaa tgaccgttga
     8401 cgcggacctt cgccgggccc accggcgagg tccgctggaa ccgcctcggc ggggagggcc
     8461 accgccggtc gtcctgccgc acggcacccc gtgctcgtcc cttcgcctga cgcgcggtgc
     8521 cccggtcacc cgcccgcgtc cacctggcgt acatccggga cgcgcccggc tacgggcagt
     8581 cggagaagac catgaccggc aggacgtccc cctggtcgcc cgaggccgtg tcttcggcga
     8641 gttcccggtc caccgggaac cagccgaacc cctggtcgtg acccacgact tcggtggcgc
     8701 cgtcgccctg cgcgcccacc tgctgcacgg cgcccgctac cgcgcgctcg ccctcgtcga
     8761 cccggcggca ctggccccgt gggactcgcc gttcttccgc ctcgccggtg aacactcccc
     8821 cgtcctcgag cagttgccgc ccgcaccgca cgccgcactc gtccgcgcgc acatcggcac
     8881 gaccggcggg cccgatccgc accccgccgt cccggagcgg ctcgtcgagc cctggctcgg
     8941 cacggcgggc cggccgacgt cccaccggcg gatcccccag gccgaccagt ggcacaccga
     9001 caagatccag ggccgctact ccgtcatggt gtgctggggc acggatgaca catggatccc
     9061 gccggagaag ggccgtgagc cggccgccgc gatacccggc gcctcctttg agccggtccc
     9121 gggcaaggac cgccttgccg aggcggacgc acccgcccaa ctcattgcgg cacggcatga
     9181 gttcctccaa tcggcgacgg tttcccgccc ctgggacagc gacgctcaat ggccgaaaag
     9241 cgcccctgcg cccgcaacgc gtggtgctag cgttccgaac gagcaccact gggacgacgc
     9301 ctcggccgcg ccgtccctct tacgagggaa gccgcccctc acacggggga cgatgcgggg
     9361 gacgaggggg gaccacattc acctgcgcca gagccttccg gacacacgat cggccacggt
     9421 gagcccaccg gatggcgccg cgcgaccggt ggcctgatct cacgtgccgt gccgcgcagc
     9481 cgagttgcgc acggcaggcc cgttccgtga agccgcctcg accaccacgc cgagcgcatc
     9541 cccgcgacgc gcccacaccg cgatcccttc cgcacggcgc cgccggacgg cctccgaagg
     9601 gcgctccgag ccgtcccgcg ctccccaccg attccctccg cccgccgggt ggagggcgca
     9661 ccggcaaggg agcccacccg ggctccgtcc acgacgagga ggattctcat gaacaccgtg
     9721 caggcgtgga aggactgtgc ctaccgcgag accctggccg cggctcccgc gcaccccgcg
     9781 ggctccatcg acctgaccga ggaactgccg ggcgagcgcg gcggcgtcca ggccatgtcg
     9841 ggcaccatcg ccatcaagac catgtccgcg ccgttctgga cctgctgcaa gtaaccgttc
     9901 cggtaccacc gtccggaccc tcgcggcacg tcgcccgccc cggcgggcga cgtgccgcac
     9961 cgcgagccga cgccacccgc cgcaccccgg aaggaaagcc atgccccaga gcacccaggc
    10021 gccccacagc gccgggcccg gccgcccctc ccccgaccgc acgcccccgg cctgggtccg
    10081 ggcgctgcgc ctcggcgagc gactcacgga cggcgggccg ccgccctgcg aaccgtccga
    10141 gcgagcccgc gaacgcctcg ccgcctggcg ccggctcgcc gccttccggg acgacgaccg
    10201 cttcgcggag aacgtccgca cgctgggcac ggaccccggc acgctgctcc gcctgctgga
    10261 cgagccccca gaggagctgg ctacccgcat cccacggccc tcctgggcca cagaggacac
    10321 cgacgcccca gaaccagcga ccccgacccg aaccccgacc ccgaccccac cgacggaccc
    10381 cgtcttcctc cccttggtcg cccccgcgat ccgccgtgcg gagtcggcgc tcctgagccg
    10441 gctgaaccgc ctcggcgccg atgcccccgc gggcctcgcc gacgccctcc tcgccacgct
    10501 gcccctcgat cggctcgaca tggtgctggg accgaccctc gtcctggagg tgaacgtcgc
    10561 ccgtgtcgaa gggcggctgc gcggggacac cccggaggag cggttcgcct ccttcgccgg
    10621 gctgctggcc gacccggacc accaggcccg cttccgggcc gagtacccgg tcctcgtccg
    10681 gcaggcggcg gaggtcctgg accgctggtc cgccgcctgc gcgcggctgg cccgccacct
    10741 ccgggacgac ctgcccgacc tccgccgcga cctgctggcc ggccggcccg ccgacaccgt
    10801 acggtccgtc gcactgggcg agggcgacct gcaccacggc gggcggagcg tggcccgggt
    10861 ggagttcgcc tgcggcggcg tcgtcatgta caagccgcgc tccctcgccg tggacgccgc
    10921 cttcggcgcc ctcgccgaac gcttctccca cgacaccggc ctcgtcctgc gcgccgcccg
    10981 cgtcctggac cggaaggagc acggctgggc cgagtacatc cgccccgcgc cctgctccgc
    11041 ccccgacggc ccggccctct tctaccggcg gaccggcgcg ctgctcgccc tggtccacgc
    11101 gctgcgcggc agcgacctgt actacgagaa cgtcatcgcc gcgggagacc acccggtcct
    11161 catcgacctg gaggccctgt tccacccggg cgacggcagc gcgcccgtct ggtccgcgtc
    11221 ctccccggcg gacgccgacc cggccggcga gctgctgcac cggtccgtgc tggccaccgg
    11281 cctgctgccg ggccgacggc tggtcggccc gccggacggc cgcgctccgg cacaccacgc
    11341 cccggcccga cgcccccaga cgcaccgccc gcagacggac gccccgcaag ccgcggacca
    11401 cccccaagcc accgccctcc cccgcaccac cgacctcagc ggcatcggcg gttccgccgg
    11461 ccagccctgg ctgacgcccg tccccgtccc ggtgggcgcg ggcaccgacg aggtgcgcct
    11521 gctcccccgt gaggtggagg tgcccggggc ggacaaccgc ccgtccctgc ccgacggttc
    11581 gtccgtcgac ccgggccgcc acctccccga cctgctggcc ggcttccgga ccggctacga
    11641 ctggctgacg gagcaccgcg ccgccctcct cgcccccggc ggcccggtcg acgcgttcgc
    11701 cgacgcgccc gtccgctacc tgcaccgcga cacctacgtc tacgacaagc tgctgcgcga
    11761 gagcttccac cccgatttcg cgcgggacgc gctggaccgc gagcgcagcc tggcgcggct
    11821 ctgctcgggc tgggcgggcg ctcccgatcg gaagcggatc gtccgcgacg aactggacgc
    11881 actgctcacc ggcgacatcc cgctgttccg tgtcgtcccc ggccgccgcg acctcctcct
    11941 gtccaccggc ggaaccgtcc ccggcttcct cgcgcgcgac gggctctcgg ccgtccgcga
    12001 gggcctggcc gccctcggcc ccgaggaccg ggaccgccag gagtggatca tcaccacgtc
    12061 gttcacggac acgttgaaca aggcgggcac gccgcatacg aagcccccgc acgttccccg
    12121 cccctcttcc cccggccgcc cagcggacac ccgagccctg acagccgcgg cggaggagat
    12181 cggcgaccgg ctcctccggc tggccgtcac cgaaggcgac gcggtcggct ggctcggcac
    12241 ccgctccccc ggccccggcg tcaccgagat cgtcccgctg ggcccggacc tctacggagg
    12301 gctggccggg atcggcctct tcctcctgcg gctcgcccag gtcaccggcg cccgccgctt
    12361 ccgcgaccag gcggaccgtg tcgcggacga ggtcgcccgc cgcgtcacgg gcggcgagca
    12421 cccggacgcc ggggccctct acctgatgag tcacgacctg aaggcgggcg gtcccgcgga
    12481 ccgcttccgg gcggtccgcg acgcggtcct ccccgcgctg cggacggccg tcgccgagga
    12541 cacggcgtac gacgtgatcg acggcgccgc cgggtacgtc ctgatgtgcc tggcggcgta
    12601 cgcggccgac ggcggcccgg agtccctgga agtggcccgg ctcgccgccg accacctggc
    12661 cgcccgcgcc gagccggcgg gcgccgggct cggctggcgg cacgcgggca tccccgcccc
    12721 ggggccgctc accggcctgg cgcacggcac gtcgggggcc gtcgtcgccc tgtcccggtt
    12781 gaacgccctg caccccgacg ggcgctacgg cgcgctgatc gacggagcgc tggcctacga
    12841 ggccggcgtc ttcgagcccg acgcggggaa ctggcccgac ctgcgggagc acgcgcccgt
    12901 acggcactgg tccgcctggt gccacggcgc ggccggcgtc ggcctggccc gcgcggagct
    12961 gctgatgtcc ccggcccggc cggcggctcg tgcggaccgg gccgccgacg agctgcggac
    13021 cgcgctcggg ccgaccctgg ccgaccggga caaccacagc ctgtgccacg gcggcctcgg
    13081 caacctcgaa ctgctgctct acgccgagcg gctgggcctc gcccgcccgg gcggcctcgc
    13141 ggaccgcctc tccgccgtcc tggagcgggc acggcggacg ggctggcggt cgggtgcccc
    13201 ggcgggcgag gaggtgcccg gactgttcac gggcctggcc gggatcggcc acaatctgct
    13261 gcggttcgcg gcaccggacg acgtaccgtc ggtcctgctc ctggaaccgc ccccgggaat
    13321 caggacggcg cccccgagct gaaccgccgc agcagcggcg acagcaccag caccgacttc
    13381 gtccgctcga cgaacggctc gccggcgatc cgctccagca cccgctcgaa gtgccgcatg
    13441 tcggaggcga agatctggac gatggcgtcg gcctcaccgg tgacggtgga ggcggacgcc
    13501 acctccgggt agcgggagag gccgcggtgg atcgcctcgg gcgaggtgtt gcggcggcag
    13561 tagagctcga tgaagccctc ggtctcccag ccgagggctc ccgggtccac ccggacggtg
    13621 aacccggtga tggccccttc ggcacgcagc ctgtccacgc gccgcttcac cgcgggcgcg
    13681 gacaggccga cctcggcgcc gatgtcggcg taggagcgcc gggcgtcctc ggccagggcg
    13741 tgcacgatac gttcgtcgag ctcgttgagt cgcactgcgg gtgaatcact tttctacggg
    13801 atcctgctgt tcctccagca gtagatcacg tatccggcgt ccaccccgac tcgcggcggc
    13861 cgggctagcc cttggcgggg gcctccgacg cgtccgcctc ggccgagccg tcgtccgtcc
    13921 cgccgttcag ccgcgagtgc cgcatgccgt aggcgaagta gatgacgaag ccgacggcca
    13981 tccagaggcc gaagacctcc caggtgacgg tgggcagctt gtacatcagg tagaagcaga
    14041 gcccgaagcc gatcaccggg aagatcatgc ccagccgcac ccgcagtccg ccgaagagcg
    14101 ggacgcgcac cccggacagc gggacggtga aggagcgctt catgtccggc cgctttacgg
    14161 cgaggacgat gacggccacg ttgaccaggg cgaaggcgaa gagggtgccg atgctggtgg
    14221 cgtcggcgag ctcggccagc gggacggcgg cggcgaggac gccgcagaag gcgcaggtga
    14281 tgatggtgtt ggccaccggg acgcccttgc gcgggctgac cttggcgaag gtcttgggca
    14341 ccaggccgtc gcgggccatc gcgaagagga tgcgggtctg gccgtagagg acggtcagca
    14401 ccacgctggc gatggcgatg acggcgcccg ccgccagcag cacggcccag aagctctggc
    14461 cggtgacgtc cttcatgatc ccggcgagcg cggcctcgga gccctcgaac tgcttccacg
    14521 gcagggcgcc gacggcgatc gcggcgacca ggacgtagag ggcggtgacg atcagcagcg
    14581 acagcatgat cgccttgggc aggtccttct tcgggttctt ggcctcctca cctgcggtgg
    14641 aggcggcgtc gaaaccgatg taggagaaga acaggctggc accggcgttg ctgacgccgg
    14701 ccaggcccag cggcatgaac ggcgagtagt tgccggcctt gatgccggtg aaggccacgg
    14761 cgcagaacag cagcagggcg gcgatcttca ccccgaccat gatggcgttg gcgcgggcac
    14821 tctccttggc gccgccgagc aggaacgcca tgcagaggag cacgacgagc agggcgggca
    14881 cgttgaagat gccgccgtcg ccgggcgggt tggccagcga cgccgggatc gtgacgccga
    14941 tggtgccgtc cagcagctcg ttgaggtact ggccccagcc gacggccacg gccgcgacgg
    15001 agacgccgta ctccaggatc aggcaccagc cgcagatcca ggcgacgatc tcgccgagcg
    15061 tggcgtagga gtacgagtac gaggagccgg agaccgggat ggtgccggcc agctccgcgt
    15121 aggagagcgc ggagaagagc gcggtgaggc ccgcgaggac gaacgagatc acgacggcgg
    15181 ggccggcgtc cggcacggcg gtgccgagca ccacgaagat gccggtgccg agggtggcac
    15241 cgatgctgat catggtcagc tgccacatgc cgagcgagcg gcgcagcgta ccgccctcgc
    15301 cctggccgcc ctcggcgacc aggcgctcga ccggcttgcg ccgcatcagt cgggaaccgg
    15361 tcccggcggg cggctgcggg gggcgcttgc cgttgccggc ggcggggggc gctgtgtctt
    15421 ggtccagcac gggggtcgct ccgttcatcg cggccggtgg agccaccggt accgcaagcg
    15481 gccccgtcgg ttgcgtcggc agggggacga ccggaaagga gggggaccgc gagctagcgg
    15541 tacccgccac tccacgtact gcgcggaacc ctacgaggtg agggaccgcg ctcgtaatgc
    15601 accattcttg cgcatgcccg tacgatcgtt gcgtctgcgt gccaagaatg ggcgttcgtt
    15661 gcatgtcacc ttacgaatcg gtacatgtag gcgtcaacca cagcaagcgg cgggcgcgcg
    15721 gaaaacgcga gaaggggcgc ggccggatcg gccgcgcccc ttctcgggct ctgtgggaac
    15781 tactgccagc tggcgtgcag cggcttgccc tccgcgtaac cggcggcgct ctggacgccg
    15841 acgacggccc gctcgtggaa ctccgcgagg ttgcccgcgc ccgcgtaggt gcaggacgag
    15901 cggacgcccg cgatgatcga gtcgatcaga tcctcgacgc ccgggcgggc cgggtcgagg
    15961 aacatccgcg aggtggagat gccctcctcg aacaggccct tgcgggcgcg gtcgtaggcg
    16021 gactcctccg aggtgcggtt gcgcacggca cgggccgagg ccatgccgaa gctctccttg
    16081 tacagccggc cgtcggcgga ctgctggagg tcgcccgggg actcgtaggt gcccgcgaac
    16141 caggagccga tcatcacgtt ggaggcgccg gcggccagcg ccatggcgac atcgcgcggg
    16201 tggcggacgc caccgtcggc ccagacgtgc ttgccgtact tcttcgcctc ggcggcgcac
    16261 tccagcaccg cggagaactg cggccggccc acgccggtca tcatgcgggt ggtgcacatg
    16321 gcgccggggc ccacaccgac cttgatgatg tccgcgccgg cctcgacgag gtcgcgcacg
    16381 ccctcggcgg cgacgatgtt gcccgcgacg atcgggaccc gcgggtccag cgcccggacg
    16441 gccttgatcg cggcgatcat cgactcctgg tggccgtgcg cggtgtccac cacgatggtg
    16501 tccgcgccgg cgtccagcag cgccttggcc ttgccggcca cgtcgccgtt gatgcccacg
    16561 gcggcggcga cgcgcagctt gccgtcggcg tcggtggccg gggtgtagag ggtggcgcgt
    16621 agggcgccct tgcgggtgag gatgcccgcc agcttcccgt ccttgtcgac ggcgggcgcc
    16681 agcttgcggt gggccgcgtc cagctggttg aacgcctcac gtgggtcgat gtcggcgtcc
    16741 aggagcagca gctccttgga catgacctcg gacagctggg tgaagcggtc cacaccggtc
    16801 aggtcgtgct cggtgaccac gccgacgggc cggtggtccc cgtccacgac gacgccggcg
    16861 ccgtgcgccc gcttgggcag cagggacagc gcgtcggcga cggtctgggt gggggcgagg
    16921 acgatggggg tgtccagcac gtggtgccgg ctcttgaccc aggtgatgac gtcggtgacg
    16981 acctcgatcg ggatgtcctg ggggatgacc acgaggccgc cgcggcgggc gacggtctcc
    17041 gccatgcggc ggcccgcgat ggcggtcatg ttggcgacca cgagcgggat ggtggtgccc
    17101 gtgccgtccg gggcggagag gtccacaccc tggcgggaac cgaccgcgga ccggctcggc
    17161 accatgaaga cgtcgtcgta cgtcaggtcg tacggcggct tctgatcgtt gaggaaacgc
    17221 atactggctc tctcacctgc aggaatagaa ctacgaagcg ggtggggagt cagctcgaac
    17281 cagcgccgga tcgggctgag gttcctggac ccatcatcca cgatgagtcg ggctgttggc
    17341 caatgactgt gagatttcgc ggcattcctg tggattcggc cagccggtcg cggcgggccc
    17401 tgtggcatcg gccaagcccg gccggagggg ccgtcggaag gtccccttac ggtggcgcca
    17461 tgacgcacca ggagatcatc tgccgcccct cggggccgga ggacgacgcg gccgtggccg
    17521 ccctcgacgg ctccttcacc accgacaccg tgtacgcggt gacccccttc cccggctccg
    17581 ccgagggctt cgccctccgg ccggtgccgg tcgacccgcc cgtccgcaag gtgttccccg
    17641 acgacgagcc ggacggcgag gaggcggggg acggcgcccg ccggtacgcg gcgttcgccg
    17701 gcgacgagct ctgcggcttc gtcgccacct cctacgagcc gtggaaccgc cggctcaccg
    17761 tcgaggacat cgaggtggcc ccggcgtacc gggggcgggg tgtcggccgg gccctcatgg
    17821 aatgcgtcgc cgaacaggcc agggaatgcg gcgcggggca tgtgtggctg gaagtcacca
    17881 acatcaatgc ccctgccatc cgttcctatc tccgcatggg tttctcgttt tgcggaatgg
    17941 acaccacgct ttattccggg acggcgtccg agggggaaat cgcgctcttc atgagccgct
    18001 cctgctcctg atccgacccg ctcccggacg cttgggccgg cccgttcccg gacgcctggg
    18061 cgggcccgct ctccggggcc tgggcgggcc cgcctcccgc cgcgtgagcc ggcccgctcc
    18121 cgggaccgcc gcccgcaccg gccgcctctc cggcgaccgg gccggcgacc gggccggcac
    18181 cggcccgctc cggcgcgggc tccccggtga gggcggcggc cgccgccacc gccgtgcgcc
    18241 gggcccgggg cccggtggtc gcggccccga ggacggcgac gacgaggccg caggcggtga
    18301 cgatccacca cccgccgtgg ctcgccgcgg cgaagtgggt gcgcacgggc ccgtcgaggt
    18361 gcgcggagac caccgtgccg atgacggcca cgccggacgc ctggccgacc tgccgggcgg
    18421 tggacatcat cccggccgcc gtgccggccc gttcggcggg catgccggtg acggcggtcg
    18481 tggtgatcgg cgggttcatc agcccgaagc cgagcccgaa cagcgcgtgg tcggcgagca
    18541 gccacgccgt gggcgtgtcc gcgtccaccc gggtcagacc gagggcggcc agcgtgatcg
    18601 ccgtaccggc gaccaccagc ggcagccggg gcccgcgggc cgccaccagc cgtccggaca
    18661 ccggcccggc caccagcatc atcgcggcga ggggcagcgt gtacagcccc gcgtccaccg
    18721 ccgacaggcc gcggacgccc tgcaggtaga gcggctcgac gaagaggaac ccgcccagcg
    18781 cccccacccc gcagaacccg atcacgctcg ccccgctgaa gggcacgctc cggaagtagc
    18841 gcggttcgat cagcggctcc gcgcgccgcc gctcgtaccc gaccaggacc accaggacga
    18901 cggcggccag cgcgaacagc gcgacgatcg gcgccgacgc ccagccccgc tcccggccgg
    18961 tgatcaccgc gtacaccagg gaggccagca gcaccacgac gaggagctgc cccaccgggt
    19021 cgaaccggcg cacccgggcc gccttggact cggggacgaa gcggcggcac agcaccaccg
    19081 ccgcgatccc gatcggcacg ttgatccaga agatcgcccg ccagcccacc gagtccacca
    19141 gcgccccgcc gaccaccggc ccgagcgcca tgctgatgcc gagcactccg ccccacaccc
    19201 cgatcgcccg ggcccgctcg gcacggtcgg tgaaggtgtt ggtgataatg gccatggcca
    19261 cggggttgag catggacccg ccgatcgcct gcaccacccg gaaggcgacc agccagccga
    19321 gccccggcgc gaaaccgcac agcagcgacc cggtggtgaa gaccacgaga ccggccgtga
    19381 acgtgcgccg ccgcccgatg cggtccgccg tcgaccccgc gagcatcagc aggctcgcca
    19441 gcaccagaag gtatgagtcg acgatccact gcaaccccgc catcgaagcg tgcagttcgg
    19501 tcgacagggc cggcagcgcg atgttgacgg ccgagccgtc caggctcacc agcagcagac
    19561 tcgtacagca gatcagcagc accagcacgc ggcgccggcg tcctatgtcg tccggcatgt
    19621 actcccctcc cgttcccggg accggcccgg cgtttttccc ggcactttcc ctacggttcg
    19681 ggacggattt ccccgaattc cgccacccgc cccagggtgt ttcgggccgt cttcagaatc
    19741 cggcattccc cgcatgacta caaaggcgat tccggcactc ataagaagcg agggcgccgc
    19801 cgacccggag agaggggtgt tccgggccac cgcgccgggg atacgcaccg agcgcccggg
    19861 ccgcgaccgc cacgtactcg ccgtgcgggc cggcaacccg ctcacggaag gcgagctacc
    19921 ggccgagcgg agcgccgcgg cacctccaga cgtcccggca cggccggacc ggtcatccgc
    19981 tcgacgacgc gccggccggg accggccacc ggcggcgggt gtgcgcgacc gcgccgacct
    20041 acgcggcgac gccgccgctc ctgaggggat cgcggagctt cgtctccgtc atcccaccgt
    20101 cgagacgctc ggcccggccg tccgggagct gccgttcgcc ctgccaccgg tcgacctctc
    20161 ccagacgtgg caccggcgcg cacccggcgc acctccggct gcgcgcccgg gtccgcgagg
    20221 cggtcgggac ggtcctcggt ccgcgggagg ctcagacgtc cgggtcggcg cggtccagcg
    20281 cgggccgggg gccgggcgcg gactcggtca gcaggtagtc ggccgcggcc gtgtccgtca
    20341 ccaggctggt gaccaggccc gaacgcagca ccgcgccgat cgccgccgcc ttgcgcgcgc
    20401 cgcccgcgat ggccacgacc tcggggatgc ggcggagccg gtcggcctcc acggtgatgc
    20461 agcgctcgcc caggtcccgc ccgatccggc ggccctcggc gtcgaagagg tgcgccgaca
    20521 tctcggcggc ggcgcccagc gacgcgtagt gggtgcgctc ctcgtccgac agcatgtcgt
    20581 agaccgtgga gatgcccggc tcccaggagc cgatggagac ggcggcgacg gtcaccttgt
    20641 cgaagtactc gaaggcccgc gcgatgcccg tctgaccgcg cagcgcggcg gcggtggccg
    20701 ggtcggggag cagcatcggg gcgtagatcg ggtgcgcctc gccgccggag acctgggccg
    20761 cccggcgcac ggcctcgacg gagccgcgct cggcggtgcc cgcgtcgtag acgccggtga
    20821 gctggacgac ggtgcagggc ggcagccggt gcagggccgc cgccatgtgg atggtggagc
    20881 ggccccaggc caggccgagc acgtcgccct cgttgaccag ctcgccgagc agtccggcgg
    20941 ccacctcgcc caggttctcc gggtcgggcg cgtcctcggc cgcgtcggcc ggggactcga
    21001 cgacgacggc gtgccgcagg ccgtagcggg cgcgcagcgc gtcggagcgc tccgcgtcca
    21061 gctcggcggg cacccggatc tcgatgcgca ccagatcgcg ttcgagcgcc gtctccagca
    21121 cccgggccac cttgaagcgg ctcacgccga actcctcggc gatctggatc ttggacttgc
    21181 cctccagata gaagcggcgg gccatggccg ccgcctgcac gagttcggcg ggccccatcg
    21241 gcgtcactga acggcccgtc gacaccgcgt tctcctcact gctgcgttca ccttgtggac
    21301 tcgaccgtca catcctgtca gaaaacagcg gtcccgatct tcctccggtc ccgtacccgg
    21361 cctccggacc cggtggttca gtgcccgcag gcccagggcg cggccgaggt ggccgtctcc
    21421 gcgagctcac gcagtgagcg tacggcggcc gccgggtcat cggtaccgta aacggccgaa
    21481 cctgcgacga acacatcggc gcccgcctcg gcgcaccgct cgatggtctc cgccgagacc
    21541 ccgccgtcca cctggagcca gagctccaga ccgtgccggg agatcagctc ccgggtgcgg
    21601 cggatcttcg gcagcatgat gtccaggaac ttctgcccgc cgaagcccgg ctccacggtc
    21661 atgatcagga gcatgtccag ctcggggagc aggtcctcgt acggctcgat cggcgtcgcg
    21721 ggcttgagcg ccatcgacgc ccgcgccccc ttggcccgga tctcccgcgc cagccgcacg
    21781 ggcgcggcgg cggcctccac gtggaaggtc accgacccgg cgcccgcctc cacgtactgc
    21841 ggggcccagc ggtccgggtc ctcgatcatc aggtggcagt ccagcggcgt ggacgtggcc
    21901 cggctcagcg actcgacgac cggcaccccg agcgtgaggt tggggacgaa atggttgtcc
    21961 atcacgtcga cgtggagcca gtcggcgccc ttgacggcct gcgcctcgtc ggccaggcgg
    22021 gcgaagtccg cgctgaggat gctggggttg atctggacgg tcatgcccca agcctgccat
    22081 gcggcggccg ccggccggac agcgagggtc gccctcgccg gcggcgcggc ccggcatcgc
    22141 cggacgagga gacggggccc cgggggcggt gccaggcttc ggccccgtgc cgccccggcc
    22201 ggcggccgac tggctgcccg aggcgggtta ccggccgggc gtcgacctct tcagggacgt
    22261 cacgatcccg caccgcccgg gaaggagacg ggaccccgcg gacgccgcca ggccccggcc
    22321 tgtgccacag cggcgcgcgg tcggccgacg gcccggagcc gaccggtcag cccgtgcgtc
    22381 gcagcagcgc caggtacatc gcgtccgtgc cgtgcaggtg cggccacagc tggacgtccg
    22441 ggccgtcgcc gagcgccggg acgccgggca gcagcgggcg ggcgtcgatc cactcggcct
    22501 cgacgccgtc gcgcttgagg acgtcctgga ccacggcccg ggtctccgcc gggtgcgggg
    22561 agcaggtggc gtagccgacg acgccgccaa tccgcacgga cagcagcgcc tcgtgcagca
    22621 ggtcgcgctg gagcggcccg aacccggcca cgtcctccgc gcgccgccgc cagcgggcct
    22681 cggggcggcg gcgcagcgcg cccaggccgg tgcaggggac gtcgacgagg gcgcggtcga
    22741 acgagccggg acgccacggc gggcgggtgc cgtcggccgt caccacctgg tacgggccgg
    22801 ggttgccggc cagcgcgcgg ccgaccagcc gggcgcggtg cggctggcgc tcggcggcga
    22861 gcagggcggc gccgcgctcg gcggccaggg cggcgagcag cgcggccttg ccgccgggtc
    22921 ccgcgcagcc gtccagccag cggcggtcgg gcccgtccag cggggccgcg gcgagggcga
    22981 gggcgacgag ctggctgccc tcgtcctgga cgccggcccg gccctcgcgc acggcgtcga
    23041 tcgcgccggg ctcgccgccc tcgaccagcc ggacggcgtg cggcgaccag cggcccggca
    23101 gggcgccgtc ctcgccgagc gccgtcagca gctcggcggt ggtggcgcgg ccgggccgcg
    23161 cgacgagggt gacgtcgggc cgctcgttgt cggcgtcgag caggtcctcg atgccggcgc
    23221 ggccgccgcc gagcgcgtcc cacagcgcgg agacgatcca gcgcgggtgc gcgtggacga
    23281 cggcgaggtg ctcctcgggg tcgtcgtcgt agggcggggc gacccgctcc agccagccgt
    23341 cc
//
