LOCUS       NZ_CP072827            22492 bp    DNA     linear   CON 18-JAN-2024
DEFINITION  Streptomyces mobaraensis NBRC 13819 = DSM 40847 chromosome, complete
            genome.
ACCESSION   NZ_CP072827
VERSION     NZ_CP072827.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces mobaraensis NBRC 13819 = DSM 40847
  ORGANISM  Streptomyces mobaraensis NBRC 13819 = DSM 40847
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7574085)
  AUTHORS   Li,P.
  TITLE     Telomere system of Streptomyces mobaraensis DSM40847 linear
            chromosome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7574085)
  AUTHORS   Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2021) Institution of Microbiology, Jiangxi Academy
            of Science, Changdong Road 7777, Nanchang 330012, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly         :: AORZ00000000
            Genome Coverage                   :: 60.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/18/2024 06:31:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,545
            CDSs (total)                      :: 6,448
            Genes (coding)                    :: 6,310
            CDSs (with protein)               :: 6,310
            Genes (RNA)                       :: 97
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 23 of 138
            Pseudo Genes (incomplete)         :: 120 of 138
            Pseudo Genes (internal stop)      :: 5 of 138
            Pseudo Genes (multiple problems)  :: 9 of 138
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:35:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 505358
            Orig. end                         :: 527850
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP072827.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22492
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="guanidinotides"
                     /region_number="4"
                     /rules="(pgm1 and pgm_amidino)"
                     /tool="antismash"
     cand_cluster    1..22492
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(pgm1 and pgm_amidino)"
                     /kind="single"
                     /product="guanidinotides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22492
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12492](+)"
                     /cutoff="20000"
                     /detection_rule="(pgm1 and pgm_amidino)"
                     /neighbourhood="10000"
                     /product="guanidinotides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12492
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(pgm1 and pgm_amidino)"
                     /neighbourhood="10000"
                     /product="guanidinotides"
                     /protocluster_number="1"
     misc_feature    1641..1655
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     misc_feature    complement(1931..1946)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            1932..2471
                     /locus_tag="J7W19_RS01960"
                     /old_locus_tag="J7W19_01960"
     CDS             1932..2471
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471485.1"
                     /locus_tag="J7W19_RS01960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_01960"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_004942085.1"
                     /transl_table=11
                     /translation="MTRLTATRLVSVAAAAGIALAAASGTAGAAQDGPDTASGTPTCGT
                     SDLRISFAERLGGGMNHAGGTLELKNTTQRTCALRGYPGLGLADSQRKALPSHTVWGST
                     WYADDPGNKLIYLKPGEAAQANVAWTHSGTAARKGTYLLVTPPAARTHQAVPLDDLVDN
                     GELHVTAVAHKVPVRG"
     gene            2799..3671
                     /locus_tag="J7W19_RS01965"
                     /old_locus_tag="J7W19_01965"
     CDS             2799..3671
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537271.1"
                     /locus_tag="J7W19_RS01965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_01965"
                     /product="isocitrate lyase/PEP mutase family protein"
                     /protein_id="WP_004942082.1"
                     /sec_met_domain="PEP_mutase (E-value: 3.5e-31, bitscore:
                     107.1, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHPNRLRAAIADTGTTPLIGVFDMFSASVAARHYDGMFVSGFGF
                     AASHYGLPDIGFIAWPDLVGFVQRLRQAFPAQHLLVDIDDGYVDPETACHVVRSLEQVG
                     ASGVILEDQKRPRRCGHVDGKLILPLEEYLEKLDMVLQARRDMVVVARTDATDEPEILR
                     RAKALAATDCDVVLVDGVRSVDWIRKVRDVIGDKPLLFNQIAGGKSPRLSLPELSELGV
                     DVAIYSTPCLFAAQTAMDEALTGLKRDDGRLPAFTPASVGVADCLALLERNISRHHDRE
                     HDRTPVTAG"
     misc_feature    complement(2810..2830)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.04"
                     /tool="antismash"
     gene            complement(3715..4941)
                     /locus_tag="J7W19_RS01970"
                     /old_locus_tag="J7W19_01970"
     CDS             complement(3715..4941)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016472665.1"
                     /locus_tag="J7W19_RS01970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_01970"
                     /product="aromatic acid exporter family protein"
                     /protein_id="WP_040888820.1"
                     /transl_table=11
                     /translation="MRDLPESLTTLVRRGREPAVAQTVRSTAAAVIAYVVALTLSSEPA
                     PLTAPLTALLVVQVTLYSTLTTGIRRVNSVVAGVLIAIGFSVLVGLTWWSLGLIILASL
                     VIGRFVHVGEFVPEVAISAMLVLGVTRVTETAWDRVLETLIGAVVGLLFNVLLVPPVWV
                     EPAGDAIQDLARRISGLLRHLGSEVGRPTPVTEAAARLHEARRLDHDVAEVDVSLRQAE
                     DSLRLNPRVKEGLLSRIVLRTGLDALEISAVVVRVMCRSLTDLARERTDEPLFPEDVAA
                     ALTDVLDHLARALESFAVLITSQVSANAEEAESRLVEDLAVGRESRDRAAHLLLDKVRE
                     HPRQWQLHGSLLAEIDRILDELDVEKRTERLTEELDRHSRASRERWPLLHRIRRRVVRS
                     RFGSRSTRA"
     misc_feature    complement(4935..4953)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.31"
                     /tool="antismash"
     misc_feature    complement(4943..4954)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.41"
                     /tool="antismash"
     misc_feature    5177..5191
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     gene            complement(5316..6911)
                     /locus_tag="J7W19_RS01975"
                     /old_locus_tag="J7W19_01975"
     CDS             complement(5316..6911)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044287.1"
                     /locus_tag="J7W19_RS01975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_01975"
                     /product="hypothetical protein"
                     /protein_id="WP_004942078.1"
                     /transl_table=11
                     /translation="MARRERPLDPGDSPLLRFAADLRALRERAGSPTYRQLALRAHSSA
                     ASLSVAAGGRRFPTLAVTSAYVRACGGDVGEWADRWHAVAAALARRRPPPYAGPAAYTA
                     ADGDRFFGRERLVEEAVERLRRDRFVVVSGASGAGTTSLLQAGVVHRLATAEDPPAVGT
                     FVPGPDPVAELARGLARLPDPDSVLVVDQLERLQAPAPAGRGRSAGPADLPGLLDVLLA
                     APCRLVLGLRTDLHERFAGHPLLAGEPLTVPAPTPEDLTRVVTEPAAAADCTVEDRLLA
                     VLVTGAHRQPGGLALLSAALLATWRHRDGNRLTLAGFHAAGGFEGAVTRGAEAVWAELA
                     DGPRQRARGILLRLTEPGDDGAPRALDRRELGDAPGTAAALERLAAARVLTLDRDRAVL
                     AHGAVAQGWPRLAAWTAEDPEALRRRRRLTRAARAWEESGRDPETLWRGRRLAEAEAES
                     ATRAPGCPDAAYPPGGPEREFLAACATAERARRVQDAVRDARLRAQRRLIAFLAGLLIS
                     VSALAAATVPLAVR"
     misc_feature    complement(6540..6542)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7030..7044
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.53"
                     /tool="antismash"
     misc_feature    7033..7053
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.29"
                     /tool="antismash"
     gene            7225..8202
                     /locus_tag="J7W19_RS01980"
                     /old_locus_tag="J7W19_01980"
     CDS             7225..8202
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015297.4"
                     /locus_tag="J7W19_RS01980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_01980"
                     /product="CoA ester lyase"
                     /protein_id="WP_004942076.1"
                     /transl_table=11
                     /translation="MKYSRYCRSLLSTPATAVHRYAAGHRSGADISMVDLEDSVPPARK
                     EEARRRAEGFFTLPTAATTRCAVRINAISGPDGLRDLLALRQYAVKPPLVLIPMVESRR
                     DVEIVEHVLGPECPDTEFVAVVETPRGLQHAAGIASSSRRLRALVFGSADYAFATGARL
                     TWDALAHPRGVLVNSARAAGIEVMDAPFFEVHDDGALRCEAALAKDMGFSGKIAVHPRQ
                     VPLINEAFSPDDDTLGRARRIVAAGRENGRDITVVDGVMIGIPFFEASQRLVEEFGDGL
                     PGPPAPSPGSDGPPSPRPAVALHRQPRPYPDAPRSTTVTQEREQ"
     gene            8199..9440
                     /locus_tag="J7W19_RS01985"
                     /old_locus_tag="J7W19_01985"
     CDS             8199..9440
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (180-406). E-value:
                     3.4e-17. Score: 54.5. Matches aSDomain:
                     nrpspksdomains_J7W19_RS01985_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007383336.1"
                     /locus_tag="J7W19_RS01985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_01985"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_004942074.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.7e-15, bitscore:
                     54.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDTNPPGPTPEITGPHRYRNSATMIRTADPAWLGAAQAGLIGVV
                     ADSPDANNRLVTPDGHEFVNMCSCSYLGLNHHPAVVEGAIEALRETGATSLVMPTTRVR
                     HRLLARLEEELGDLFGCHALPGASCSALTAGILPLIASGHLSDGQPRVMVFDRFCHFCM
                     SYMKPVCGDESLVLTCDHNDLDRLEEICRTYPRVAYVADGAYSMGGAAALDGLRRLQER
                     YGLFLYLDDSHSLSILGEHGEGFARSQLEMNELTVITASLGKAFGTAGGIAMLGSREMF
                     EFLHRHAGPVGWSQNMSFPVVGASLASAAIHRSPELGELQRRLQENIAYFDTAFPTAFA
                     GNGLPVRRITVGDPEAAVKLSADMFQRGFYCSAVFFPIVPKGEAGLRIMIRADLSREKL
                     DEFIGHIKDLSPTH"
     aSDomain        8739..9416
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J7W19_RS01985_Aminotran_1_2.1"
                     /evalue="3.40E-17"
                     /label="J7W19_RS01985_Aminotran_1_2.1"
                     /locus_tag="J7W19_RS01985"
                     /protein_end="406"
                     /protein_start="180"
                     /score="54.5"
                     /tool="antismash"
                     /translation="HNDLDRLEEICRTYPRVAYVADGAYSMGGAAALDGLRRLQERYGL
                     FLYLDDSHSLSILGEHGEGFARSQLEMNELTVITASLGKAFGTAGGIAMLGSREMFEFL
                     HRHAGPVGWSQNMSFPVVGASLASAAIHRSPELGELQRRLQENIAYFDTAFPTAFAGNG
                     LPVRRITVGDPEAAVKLSADMFQRGFYCSAVFFPIVPKGEAGLRIMIRADLSREKLDEF
                     IGHI"
     gene            9456..10004
                     /locus_tag="J7W19_RS01990"
                     /old_locus_tag="J7W19_01990"
     CDS             9456..10004
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011039352.1"
                     /locus_tag="J7W19_RS01990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_01990"
                     /product="MaoC family dehydratase"
                     /protein_id="WP_004942071.1"
                     /transl_table=11
                     /translation="MADDAPPSGYERLGPQHYREVVGFLYEEFTVGDVIEHRPGRTVTE
                     MDNVLMSTLSMNDAPLHIDAAFCADTPWGRPLVSSLVTLSIVGGMTARSTSGKALANLG
                     WDRIRLPNPVFTGDTLYATTEILGKRLSRSRPGEGIVSCRTTGTKSTGEVVLVFERSFL
                     VPCRDPEPGGPAAAPRGDG"
     gene            10001..11311
                     /locus_tag="J7W19_RS01995"
                     /old_locus_tag="J7W19_01995"
     CDS             10001..11311
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     guanidinotides: pgm1"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF037360.4"
                     /locus_tag="J7W19_RS01995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_01995"
                     /product="peptide ligase PGM1-related protein"
                     /protein_id="WP_004942069.1"
                     /sec_met_domain="pgm1 (E-value: 4.8e-162, bitscore: 537.9,
                     seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALLIGNNRAAEMTGGPDGTPEERRRAARGAQRLLWWARDGDVL
                     LLPEAPDDAFADHVTGLTGTRRAGLTVVTAALPPTGALPDATVAAVRAALAGRTVDRVM
                     PVYADTGVTGLVRRLGAERALPGWAFHDQGGSALVNSKAAFRAVAAGTGTPVAAGTVAG
                     SPDAAGAAAAELLAAGHPAVLKLAFHSGGLGNEVLTTDPAVRPLGAHRAVVLPGPDAAR
                     EHTARHWAGLSSGGRHPVVVERYHPESVPVYAEFEVRDAGVVLSGHGEMLMDPMLDGET
                     VPAALPPDLLDRLVGHGRRLCEAYRALGYRGTLSADAIVTPAGELLFTEANGRLTGSSH
                     LHSVLAARLVGEPLRSRRVFLEKGAWPVPSFGAALDALDRAGLAFDPATRTGVVLVGDR
                     VPVDGTVVPCVIAPDRPAAHAVRRSLPVFAAEPAPAS"
     gene            11326..12492
                     /locus_tag="J7W19_RS02000"
                     /old_locus_tag="J7W19_02000"
     CDS             11326..12492
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     guanidinotides: pgm_amidino"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356477.1"
                     /locus_tag="J7W19_RS02000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02000"
                     /product="hypothetical protein"
                     /protein_id="WP_004942068.1"
                     /sec_met_domain="pgm_amidino (E-value: 1.6e-188, bitscore:
                     624.6, seeds: 95, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLNSYDSWSPLREVVVGSAENYSSHERELSFDLFFHDEMPYSRM
                     YYPRHRAPGGDASGEDGTGTGARQSPIKKRYVEELQEDVEGMVDTLASLGVTVHRPAPL
                     AEHIEVRTPTFRAAVIPALNVRDNSIVLGDEVIETAPQVRARYFETQLLKPVFADYFRR
                     GARWTVMPRPLMTDASFDLSYVTAHTAPGELMEPITDPRPSPYDVGHEMMIDGAQCLRL
                     GRDVFVNVSTANHVLGCDWLERHLDGRFRVHRLDSLSDSHIDSTVLALRPGLLLVRTPQ
                     IAERLPKPLRSWDMIFPPEPEDNQFPVYDADDLLLTSRYIDLNVLSVSPDTVLVNSACP
                     ELIRTLEKHRFTVVPVRHRHRRLFGGGLHCFTLDTVREGSAPEDYLEG"
     gene            12498..13439
                     /locus_tag="J7W19_RS02005"
                     /old_locus_tag="J7W19_02005"
     CDS             12498..13439
                     /NRPS_PKS="Domain: PKS_ER (17-306). E-value: 3.3e-38.
                     Score: 123.5. Matches aSDomain:
                     nrpspksdomains_J7W19_RS02005_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024989.4"
                     /locus_tag="J7W19_RS02005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02005"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_004942066.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.5e-20, bitscore:
                     70.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVVIRRFGGPEVLETAELPEPVAGAGESVVDVVLAGVNFGDLE
                     VRAGTYRPPRLPAVLGAEIVGVRRRDGRRVAALLRDGGGYAEVAVARDAYTVELPDDID
                     DLAGAALVEQGCTAYAALVTAGRLRPGERVAVASAAGGVGHLAVQLARALGASAVAGTA
                     STAAKRQFVRELGADHAAEGPEALPALFPDGVDLYLDSLGGPRVEAALAALAPFGRLVS
                     IGHREEPAVVAVDALTRRSLGVVTLWMRQVLEADGLFAEVAGRVLALAGEGRLVPHVDR
                     VVPLDGVGGAHEAVAARATTGKVLVDVRAAGC"
     aSDomain        12549..13415
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J7W19_RS02005_PKS_ER.1"
                     /evalue="3.30E-38"
                     /label="J7W19_RS02005_PKS_ER.1"
                     /locus_tag="J7W19_RS02005"
                     /protein_end="306"
                     /protein_start="17"
                     /score="123.5"
                     /tool="antismash"
                     /translation="AELPEPVAGAGESVVDVVLAGVNFGDLEVRAGTYRPPRLPAVLGA
                     EIVGVRRRDGRRVAALLRDGGGYAEVAVARDAYTVELPDDIDDLAGAALVEQGCTAYAA
                     LVTAGRLRPGERVAVASAAGGVGHLAVQLARALGASAVAGTASTAAKRQFVRELGADHA
                     AEGPEALPALFPDGVDLYLDSLGGPRVEAALAALAPFGRLVSIGHREEPAVVAVDALTR
                     RSLGVVTLWMRQVLEADGLFAEVAGRVLALAGEGRLVPHVDRVVPLDGVGGAHEAVAAR
                     ATTGKVLV"
     CDS_motif       12888..12950
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J7W19_RS02005_0001"
                     /evalue="1.30E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="J7W19_RS02005"
                     /protein_end="151"
                     /protein_start="130"
                     /score="14.7"
                     /tool="antismash"
                     /translation="GERVAVASAAGGVGHLAVQLA"
     gene            13528..13953
                     /locus_tag="J7W19_RS02010"
                     /old_locus_tag="J7W19_02010"
     CDS             13528..13953
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359182.1"
                     /locus_tag="J7W19_RS02010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02010"
                     /product="cold shock domain-containing protein"
                     /protein_id="WP_106429567.1"
                     /transl_table=11
                     /translation="MSVVTGKIIRFDEFRGYGFVAPDTGGEDVFVHVNDVQADKRLIVP
                     GAFVEFSVEEGERGLKASHVRLLDRASGRPAEVPAEGYVPGPSGDDGDCDVLSAKEFTD
                     EVTELLLSAAPTMTAEQILLVRQRLVRLAANHGWVEA"
     gene            complement(14280..15479)
                     /locus_tag="J7W19_RS02015"
                     /old_locus_tag="J7W19_02015"
     CDS             complement(14280..15479)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000102: Other (69% identity)"
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077963.1"
                     /locus_tag="J7W19_RS02015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02015"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_004942063.1"
                     /transl_table=11
                     /translation="MAGRRPTIAVVGGGIGGLAAAVALRRSGLDAVVHEQAAEPTATGA
                     GVAIGANGHRVLRSLDVDRRLAATAVAPSRVDFRHWRTGRTVAGLGVGDGYERRFGAPF
                     WHLERSALQDALLAAADGIPVRFGARCTGVEQTPDGAVVRFADGSAAEADAVVGADGIH
                     SAVRDAVFGPDEAVFSGTSGYRALVPLDRLPDLPELADPVLWLWVGPGRHVVVYPVAGG
                     RLLNLLAVVPDPAWTVESWVTEGRTADLLAAFDGWHPALTGLLAAVDRPGRWALYDREP
                     RRSWTRGRVTLLGDAAHPMLPHHGQGANQALEDAAVLAALLADAAPTDVPAALRRYERT
                     RRPRTRAIQAGSRQNATCLHLPDGPQATARDANLTTLPDRLAWIHGHDPLGALTTPARG
                     "
     gene            15682..16911
                     /locus_tag="J7W19_RS02020"
                     /old_locus_tag="J7W19_02020"
     CDS             15682..16911
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018840558.1"
                     /locus_tag="J7W19_RS02020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02020"
                     /product="MFS transporter"
                     /protein_id="WP_004942061.1"
                     /transl_table=11
                     /translation="MPKNRSLTFRDRPILLLSTGHACVDVYQGAVAALVPFFVSERAYT
                     YAAASGIVLAASLLSSVVQPLFGALTDRWAMPWLLPVSTLLAGAGVALSGLGGSYALTL
                     AVVAVSGIGVAAYHPESARVARRASRGSHVAMGWFSLGGNLGFAAAPLLVSAVVATGGL
                     RATPLLALPAVAGAALCAAALRMARAPGDAPGARAASRAAGRDDWASFRRLTGAIMCRS
                     VVFVGLSAFVSLHVRQRTGWGQLAGTAALFVLYLGGAVGTVAGGRLAGRYGRTTVVRWS
                     YALAVPAVAGVVLVPGPALYLFVALTSAALYVPFSLHVTLGQDYLPRRVGTASGVTLGL
                     AVSVGGVASPLIGALADVTSLRVALAPLIALPAVGWLLLRPLREPGAPGAPRVPGAAPA
                     ADAPSAPREV"
     gene            16988..18073
                     /locus_tag="J7W19_RS02025"
                     /old_locus_tag="J7W19_02025"
     CDS             16988..18073
                     /EC_number="1.1.1.306"
                     /GO_function="GO:0050607 - mycothiol-dependent formaldehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0010127 - mycothiol-dependent
                     detoxification [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (23-256). E-value: 3e-12. Score:
                     38.2. Matches aSDomain:
                     nrpspksdomains_J7W19_RS02025_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381558.1"
                     /locus_tag="J7W19_RS02025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02025"
                     /product="S-(hydroxymethyl)mycothiol dehydrogenase"
                     /protein_id="WP_004942059.1"
                     /sec_met_domain="ADH_N (E-value: 6.4e-28, bitscore: 95.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2e-29, bitscore:
                     100.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQEVRGVVAPGKNQPVRVETIVVPDPGPGEAVVKVQACGVCHTD
                     LHYKQGGINDDFPFLLGHEAAGVVEAVGEGVTEVAPGDFVVLNWRAVCGQCRACLRGRP
                     QYCFATHNARQKMTLTDGTELTPALGIGAFAEKTLVAAGQCTKVDPEVSPAVAGLLGCG
                     VMAGIGAAINTGGVSRGDSVAVIGCGGVGDAAVAGSRLAGAARIIAVDIDDRKLETARR
                     MGATHTVNSRTTDPVEAIRELTGGFGADVVIEAVGRPETYEQAFYARDLAGTVVLVGVP
                     TPDMRIDLPLLDVFGRGGALKSSWYGDCLPSRDFPMLVDLHLQGRLDLAAFVTETIGLG
                     DVEAAFDRMHQGDVLRSVVVF"
     aSDomain        17057..17755
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J7W19_RS02025_PKS_ER.1"
                     /evalue="3.00E-12"
                     /label="J7W19_RS02025_PKS_ER.1"
                     /locus_tag="J7W19_RS02025"
                     /protein_end="256"
                     /protein_start="23"
                     /score="38.2"
                     /tool="antismash"
                     /translation="VPDPGPGEAVVKVQACGVCHTDLHYKQGGINDDFPFLLGHEAAGV
                     VEAVGEGVTEVAPGDFVVLNWRAVCGQCRACLRGRPQYCFATHNARQKMTLTDGTELTP
                     ALGIGAFAEKTLVAAGQCTKVDPEVSPAVAGLLGCGVMAGIGAAINTGGVSRGDSVAVI
                     GCGGVGDAAVAGSRLAGAARIIAVDIDDRKLETARRMGATHTVNSRTTDPVEAIRELTG
                     GFGADVVIEAV"
     CDS_motif       17168..17206
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J7W19_RS02025_0001"
                     /evalue="1.40E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="J7W19_RS02025"
                     /protein_end="73"
                     /protein_start="60"
                     /score="11.6"
                     /tool="antismash"
                     /translation="LGHEAAGVVEAVG"
     CDS_motif       17792..17824
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J7W19_RS02025_0002"
                     /evalue="1.00E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="J7W19_RS02025"
                     /protein_end="279"
                     /protein_start="268"
                     /score="3.0"
                     /tool="antismash"
                     /translation="RDLAGTVVLVG"
     gene            18073..18702
                     /locus_tag="J7W19_RS02030"
                     /old_locus_tag="J7W19_02030"
     CDS             18073..18702
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007448769.1"
                     /locus_tag="J7W19_RS02030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02030"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_004942056.1"
                     /transl_table=11
                     /translation="MPARIDHLVTSGTFSLDGGTWEVDNNVWIVGDDHEAIVIDAAHDP
                     DAVAEALGDRRLLAVVCTHAHDDHVNAAPALADRTGAPVLLHPDDRPLWDRTHPDRAPD
                     GELADGQVLRVAGTELTVLHTPGHAPGAVCLHAPELNTVFTGDTLFQGGPGATGRSFSD
                     FPTIVASIRGRLLTLDGDTVVRTGHGDTTTIGAEAPHLEEWIARGH"
     gene            18807..19439
                     /locus_tag="J7W19_RS02035"
                     /old_locus_tag="J7W19_02035"
     CDS             18807..19439
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087901.1"
                     /locus_tag="J7W19_RS02035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02035"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_004942054.1"
                     /transl_table=11
                     /translation="MDMTDLVEITEPGELTELLGEPLPRVRDKARDRLGELDRQWLEHS
                     PFCLVATSDADGNCDVSPKGDPVGGLTLVLDDTTLAIAERPGNRRADGFRNVLANPHVG
                     LVFLVPGRGDTLRVNGRARLVREAPFLDRMTVKGHRPVLALLVEVEEVFFHCSKAFLRS
                     ELWKPETWRPDEVPSRARIAKVLERPEDSMEELETYYGPRYAERLYG"
     misc_feature    complement(19441..19458)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.5"
                     /tool="antismash"
     misc_feature    complement(19443..19461)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     misc_feature    19448..19461
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.81"
                     /tool="antismash"
     gene            19503..19964
                     /locus_tag="J7W19_RS02040"
                     /old_locus_tag="J7W19_02040"
     CDS             19503..19964
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013001888.1"
                     /locus_tag="J7W19_RS02040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02040"
                     /product="hypothetical protein"
                     /protein_id="WP_004942053.1"
                     /transl_table=11
                     /translation="MPSSSEAPKASDASRTPDPFSPPDLDQARARRVHASLFRIAERHA
                     DTEARRRRQTHPTMIGPHEAVRLVSFLLSGAALLEDGEPEVDRADITAALSLVPLMRGE
                     MDELEAGLLGMARGRGMTWPDIAFGLGLGTPQAARQRYERLADRTARDE"
     gene            complement(20005..21576)
                     /locus_tag="J7W19_RS02045"
                     /old_locus_tag="J7W19_02045"
     CDS             complement(20005..21576)
                     /EC_number="6.2.1.3"
                     /NRPS_PKS="Domain: AMP-binding (17-426). E-value: 3.6e-98.
                     Score: 320.7. Matches aSDomain:
                     nrpspksdomains_J7W19_RS02045_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF004837.0"
                     /locus_tag="J7W19_RS02045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02045"
                     /product="long-chain-fatty-acid--CoA ligase"
                     /protein_id="WP_004942050.1"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-108, bitscore:
                     360.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTPLAQRPRLLHELPDRGAARAPDAEALVCGGARLTWSDLRSRA
                     DLLRGALRTAGVDRGGRVAVVGRNGLACLETVLAAAGAGAATAILNWRLAPPELAHVIA
                     DSGATVLFADAAVLDAVRTALGTLDAPPRLVVTGDGAGPADGAETYAALLDPAEPLAAR
                     DDLDPDDTCVILYTSGTTGSPKGAELTHRGLLEQSAALLAVLSMGPADRSVAVLPFFHV
                     GGVCYVVTALLAGAPTVVLREATPEAMCAAVADGATHLLLVPAMLPGILAAGPDAVAAF
                     GRLRYCLYGASPMPLPVLRRALALFPGIRFLQLYGMTELSGAATALAPEAHRDPAHAHR
                     LASAGRPMPGVEARVVDPATRAELPPGRRGELWIRSPGRMKGYLGNPAATAETVTDDGW
                     LRTGDLARIDEDGYVFVEDRLKDLIITGGENVCPAEVERVLVEHPAVVEAAVIGVPDEK
                     WGETVRAVLVTADGVPVDPAELRAFCRERLAGFKCPTSVGTVAALPRNATGKIDKNALR
                     AAASAG"
     aSDomain        complement(20299..21525)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J7W19_RS02045_AMP-binding.1"
                     /evalue="3.60E-98"
                     /label="J7W19_RS02045_AMP-binding.1"
                     /locus_tag="J7W19_RS02045"
                     /protein_end="426"
                     /protein_start="17"
                     /score="320.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RGAARAPDAEALVCGGARLTWSDLRSRADLLRGALRTAGVDRGGR
                     VAVVGRNGLACLETVLAAAGAGAATAILNWRLAPPELAHVIADSGATVLFADAAVLDAV
                     RTALGTLDAPPRLVVTGDGAGPADGAETYAALLDPAEPLAARDDLDPDDTCVILYTSGT
                     TGSPKGAELTHRGLLEQSAALLAVLSMGPADRSVAVLPFFHVGGVCYVVTALLAGAPTV
                     VLREATPEAMCAAVADGATHLLLVPAMLPGILAAGPDAVAAFGRLRYCLYGASPMPLPV
                     LRRALALFPGIRFLQLYGMTELSGAATALAPEAHRDPAHAHRLASAGRPMPGVEARVVD
                     PATRAELPPGRRGELWIRSPGRMKGYLGNPAATAETVTDDGWLRTGDLARIDEDGYVFV
                     EDRLKDLIIT"
     CDS_motif       complement(20401..20484)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J7W19_RS02045_0002"
                     /evalue="2.70E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="J7W19_RS02045"
                     /protein_end="392"
                     /protein_start="364"
                     /score="29.3"
                     /tool="antismash"
                     /translation="PPGRRGELWIRSPGRMKGYLGNPAATAE"
     CDS_motif       complement(21004..21060)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J7W19_RS02045_0001"
                     /evalue="1.60E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="J7W19_RS02045"
                     /protein_end="191"
                     /protein_start="172"
                     /score="20.7"
                     /tool="antismash"
                     /translation="VILYTSGTTGSPKGAELTH"
     gene            complement(21681..>22052)
                     /locus_tag="J7W19_RS02050"
                     /old_locus_tag="J7W19_02050"
                     /pseudo=""
     CDS             complement(21681..>22052)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389415.1"
                     /locus_tag="J7W19_RS02050"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="J7W19_02050"
                     /product="L,D-transpeptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="CPTDKGRIACVDLTRQVSWIQDGKKIKYGPVHIRSGRKGFATRTG
                     LKKVYWRDKDHRSSLYDVSMPYSQFFDGGQAFHAIGGSVYSPPGSHGCVNMRMKDARAY
                     WNLLHKGDDVFVYGRKPGT"
     misc_feature    22184..22198
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.42"
                     /tool="antismash"
     misc_feature    complement(22231..22243)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.11"
                     /tool="antismash"
ORIGIN
        1 ggtcggtgag ttcgcccgcg gtgccgccga acagccgctg ccattcgggg gacttgaggt
       61 ggttgtatcc tgcggagccg cccccggcgg ggatgccggc ggccatgaac ggcgcgaagt
      121 cggaccggcc gtcgaactcc agcgggacgg tgggcaggcc gcgccgggcg aagcggtcgg
      181 tgaagacctt ctcgacggtg tcggtgccgg gcggtacggc gccggtgccg tggtagacca
      241 tacgggcgta gttgggcgag gcgatggtct cgaagttgag gacgagcgcg gtctcccggc
      301 gctcccggtc gttcaactgc ccgacgtagt gcccggaccc gatcatgccc tcctcctcgg
      361 cgccccagaa ggcgaagcgc acccggttgc ggacctcgtc ccggtgcggg gcgagccgga
      421 gggcggtctc caggaccatg gccgcgctgc tgccgttgtc gttgaggccg gggccctcgg
      481 tggcgctgtc caggtgcgag ccgaggacca ccgtgcggtc ggcgcgcccg gcgggggtgt
      541 cggcgagcag gttgtacgag tcggtggtga cggcccggcc gcgcaggtcg aggaagaggt
      601 cgacgggtcc gcgggcggcg tcggcggcga gccgttcggc ctcgccgcgc ggcaggttgg
      661 cggtggggac gcgggcgacg gcgggtgggc ggacggtgga gcggatgttc atcgccgccg
      721 gctgctggtc gacattcacc agcagggcgg cggcgccggc cgcggcggcc agttcggtct
      781 tgcgggccag gtcgcagccg ccgtagcggg cgaggacggc gtggccccgg acgtccccgg
      841 cgtagtcggc ggcgtcgcag ccgtacgcct tctccggcag gacggccagg cgtccgcgcc
      901 atccgccgtc cggcgtggcg ggcgagaacc gggcgagcag cgggtgcagg gtgcgcgggt
      961 cgggcccggt gacctgggcg gtctgggaca cgggcacgct gtcggggaag gagaagcgct
     1021 ggacgcggac ctggtagccg gcctcggtca gccgccgggt gacgtagcgc gccgaggcgt
     1081 cgtagcccgc ggtgccggcg gcgcggacgc cgtcgtggtc gtcggccgcg cgctggaacg
     1141 cctccaggtg gcgccaggcg ccggcggcgg tgacctccgc cgccagccgg ccggccagcc
     1201 gctcggcgtc cgcccggacg gacggcgtac gggcggacgc tccggaaacg gacgacgcgg
     1261 cagaggctcc ggaagcggga gtggctcccg gggcgggggc ggccgtggcc accaggaggg
     1321 cggcgcaggc cagcgcgcag gccggggccg ccgtccgcaa gggcgcccgg gtcagggtca
     1381 cgcgccaccg ggcgcgcgcc gggcggccgg cggcggggca ggtggcggcc ggatcggggg
     1441 aggataccgg gggcgccccc tggagagcgc gtcgagccgt ccttcgcatc atccgtcgca
     1501 agagcatctg gagtcccccg agtactcgtc cggcctgaac cgcgtgtggc ggggcagcct
     1561 aacgcgcccg ctggggcgcg caaggggccg agcggcggtt tcgggccgat gtccggccgg
     1621 gccgttcggc ccgtccggcc gggccgaacg gcccccgtac gccctccatt tcgccgattg
     1681 accgcctttg aagggggcga tgagaatcgg aacgccctcc cgcctcgcgc ccgaccgggc
     1741 gcaacccggc ctttccggaa ggggaagcag ggggaacgac gaggaaatcc gggggaagga
     1801 aagggaattc cggccgccgg ggtggcgcgt tccctacgct ccggcgcgtt cgagggcgca
     1861 tgtgacgggt aggcgcagcg agcatgacag cacgtgaaac tcgggggaac actcaaggaa
     1921 aggaacagct cgtgacacgc ctcaccgcca cacgcctcgt gagcgtcgcc gccgccgcgg
     1981 ggatcgcgct cgccgccgcg tccgggacgg cgggcgccgc ccaggacggg ccggacaccg
     2041 cgtccggcac tcctacgtgc ggcacttccg acctgcggat ctcgttcgcc gagcggctgg
     2101 gcggcgggat gaaccacgcg ggcggaacac tggagttgaa gaacaccacc cagcggacgt
     2161 gcgcgctgcg cgggtacccg ggcctgggcc tggcggactc ccagcgcaag gcgctgccct
     2221 cgcacacggt gtggggcagc acctggtacg cggacgaccc gggcaacaag ctcatatacc
     2281 tcaagcccgg tgaggccgcg caggccaacg tcgcctggac gcactccggc acggcggccc
     2341 gcaagggcac ctacctgctg gtgacgccgc ccgccgcgcg gacccaccag gcggtcccgc
     2401 tcgacgatct ggtggacaac ggcgagctgc acgtcaccgc ggtggcgcac aaggtgccgg
     2461 tccgcggctg acgtccggca cgacgagggg accggccgtc ccgagcggtg cgggcgcctt
     2521 tcggcgcaaa agcattgcac cgcccgggac tttacatttc cctgattgct ccatgaccaa
     2581 gacttgacta acctccggac cggaagtgag gggcgccact ccgcaccgag cggacccggg
     2641 ccccgagcgc gcacagcgga gcacgcacac agcacagaac ccggggcacg ccgttcccca
     2701 cggcggacac ccgggtcctg gtcagcagcg cgcggccggt cctcggcttg gcggcagcgg
     2761 tcggcgcgcg cgttgcccaa ctcaccccgg aggttaccgt gaaccacccg aatcggctac
     2821 gcgccgcgat agcggacacc ggcaccaccc cgctcatcgg cgtcttcgac atgttctccg
     2881 cctccgtcgc ggcccggcac tacgacggca tgttcgtctc cggcttcggc ttcgccgcct
     2941 cccactacgg cctgcccgac atcgggttca tcgcctggcc cgacctcgtc ggcttcgtcc
     3001 agcggctgcg ccaggcgttc cccgcgcagc acctgctcgt cgacatcgac gacggctatg
     3061 tggaccccga gaccgcctgc cacgtggtgc ggtcgctgga gcaggtcggc gcgtccggcg
     3121 tgatcctgga ggaccagaag cggccccggc gctgcgggca cgtggacggc aagctgatcc
     3181 tgccgctgga ggagtacctg gagaagctcg acatggtgct ccaggcgcgc cgcgacatgg
     3241 tcgtcgtggc ccgcacggac gccaccgacg agcccgagat cctgcgccgc gccaaggcgt
     3301 tggcggcgac ggactgcgac gtggtcctgg tcgacggggt gcgcagcgtc gactggatcc
     3361 gcaaggtgcg ggacgtcatc ggcgacaagc cgctgctgtt caaccagatc gcgggcggca
     3421 agtcgccccg gctgtcgctg ccggagctgt cggagctggg cgtggacgtc gccatctaca
     3481 gcaccccctg cctgttcgcg gcgcagaccg cgatggacga ggcgctgacc gggctgaagc
     3541 gggacgacgg gcggctgccc gcgttcacgc cggcgtccgt cggggtggcg gactgcctgg
     3601 cgctgctgga gcggaacatc tcccgccacc acgaccggga gcacgaccgg acgccggtga
     3661 ccgcgggctg acggggtccc ggggcgccgc cggggaggcg gcgccccggg accgtcaggc
     3721 gcgggtgctc ctgctgccga accggctgcg gaccacccgc cgcctgatcc ggtggagcag
     3781 cggccagcgc tcccgggacg cccgggagtg ccggtccagc tcctccgtca gccgctcggt
     3841 gcgcttctcg acgtcgagtt cgtcgaggat gcggtcgatc tcggcgagca gcgagccgtg
     3901 cagctgccac tgccgggggt gctcgcggac cttgtccagc agcaggtggg cggcccggtc
     3961 gcggctctcc cggccgacgg cgaggtcctc gaccagccgg gactcggcct cctcggcgtt
     4021 ggcgctcacc tggctggtga tcagcacggc gaagctctcc agggcccggg cgaggtggtc
     4081 cagcacatcg gtgagcgcgg cggcgacgtc ctcggggaag aggggttcgt cggtgcgctc
     4141 gcgcgccagg tcggtcaggg agcggcacat cacccggacc acgacggcgg agatctccag
     4201 cgcgtccagc ccggtgcgca gcacgatccg ggagagcagg ccctccttga cccgggggtt
     4261 gagccggagg ctgtcctccg cctgccggag ggagacgtcc acctcggcga cgtcgtggtc
     4321 gagccggcgc gcctcgtgca gccgggcggc ggcctccgtg acgggggtgg gccggccgac
     4381 ctcggagccg aggtggcgga ggagtccgct tatccggcgc gccaggtcct ggatggcgtc
     4441 gccggccggc tcgacccaga cgggcgggac gagcagcacg ttgaagagga gtccgacgac
     4501 ggctccgatc agggtctcca ggacccggtc ccaggcggtc tccgtcaccc gggtgacgcc
     4561 gaggacgagc atggcgctga tcgccacctc ggggacgaac tcccccacgt ggacgaagcg
     4621 cccgatgacc agcgacgcca ggatgatcag tcccaggctc caccaggtga ggccgaccag
     4681 gacgctgaag ccgatggcga tcaggacgcc ggcgacgacg gagttcaccc ggcggatgcc
     4741 ggtggtcaga gtggagtaca gggtcacctg gacgacgagc agggcggtca gcggcgcggt
     4801 gagcggcgcc ggttcgctgc tgagcgtcag cgccaccacg tacgcgatga cggcggcggc
     4861 cgtggaccgc accgtctgcg ccaccgcggg ctctctgccg cgtcggacca gggtcgtcag
     4921 ggattcggga agatcacgca ctgtagacgc tttcccgatc acccgcgtgg cagaccccca
     4981 ggtgaggcac gccacccggg tggtcgcggg gcctcggcga ccgcgcggtg tcggctcgcc
     5041 gacggaagcg ggggtccggc cggggccggc ccgtcgcccg gccgtacggc ccaccaccgg
     5101 gcaggccggg cggcggtacg ccgagcgccg ggcgagccgg gcggcggcgc ccgggcacgc
     5161 ccgcgccgga cgggacgggc cgtccggccg tcggcgaccg gccgacgggc cgacgcccgc
     5221 caccgccgac gcgcgggtcc cgttcggtgg acgacggtgg ccttgggcgg cggggcggtc
     5281 ggaggcgccg ccgcccgctt ggccgtgacc tcccttcagc ggaccgcgag cggaaccgtc
     5341 gccgccgcca gggccgagac cgagatcagg aggccggcca ggaaggcgat gaggcggcgc
     5401 tgggcgcgca gccgggcgtc gcggaccgcg tcctgtacgc ggcgggcccg ttcggccgtc
     5461 gcgcaggcgg cgaggaactc ccgctccggg ccgccgggcg ggtacgccgc gtccgggcag
     5521 ccgggcgcgc gggtcgcgga ctccgcctcc gcctcggcga gccggcgtcc gcgccagagc
     5581 gtctcggggt cgcgcccgga ctcctcccag gcccgggccg cccgggtgag ccgccggcgg
     5641 cggcgcagcg cctccgggtc ctcggccgtc caggcggcga gccggggcca gccctgggcg
     5701 acggcgccgt gggcgaggac ggcccggtcg cggtcgaggg tgagcacccg ggcggcggcg
     5761 aggcgttcga gggcggcggc cgtgccgggg gcgtcgccga gttcccggcg gtcgagggcg
     5821 cgcggcgcac cgtcgtcgcc gggttcggtc aggcggagca ggatgccccg ggcccgctgc
     5881 cgggggccgt cggcgagttc ggcccagacc gcctcggcgc cccgggtgac ggcgccctcg
     5941 aacccgccgg cggcgtggaa gccggcgagg gtgagccggt tgccgtcgcg gtgccgccag
     6001 gtggcgagaa gggccgcgga cagcagggcg aggccgccgg gctgccgatg ggctcccgtg
     6061 acgaggacgg cgagcagccg gtcctcgacg gtgcagtcgg ccgcggcggc cggttcggtg
     6121 acgacgcggg tgaggtcctc gggggtcggc gccggcacgg tcagcggttc cccggccagc
     6181 agggggtggc cggcgaaccg ttcgtggagg tcggtgcgca agcccagcac gagtcggcag
     6241 ggtgcggcga gcagcacgtc gaggaggccg ggcaggtccg ccgggcctgc ggaacggccg
     6301 cgtccggccg gggccggcgc ctggagtcgt tccaactggt cgacgacgag gacggagtcg
     6361 gggtccggga gccgggcgag gccgcgggcg agttcggcga cggggtcggg cccgggaacg
     6421 aacgtgccga cggcgggcgg atcttcggcg gtggcgagcc ggtggacgac gcccgcctgg
     6481 aggagcgagg tggtcccggc cccggaggcg ccggagacga ccacgaaccg gtcccggcgt
     6541 aaccgttcca ccgcctcctc caccaggcgt tcccggccga agaagcggtc gccgtcggcc
     6601 gccgtgtacg cggcggggcc ggcgtagggc ggcggccggc ggcgggcgag ggcggcggcc
     6661 acggcgtgcc agcggtccgc ccactccccc acgtcgccgc cgcaggcgcg gacgtaggcg
     6721 ctggtgacgg cgagggtcgg gaacctgcgg ccgcccgcgg cgaccgagag gctggccgcg
     6781 gacgagtggg cgcggagggc gagttggcgg tacgtggggc tgcccgcccg ttcgcgcagg
     6841 gcgcgcaggt ccgcggcgaa gcgcagcagg gggctgtcgc ccgggtccag gggccgttca
     6901 cggcgtgcca ctgccctgcc tttccagccg tgccgcacgg caccgggcct ggggtggggc
     6961 ggcggcgcga gcgagccgaa cgtagcggtg gaccttacgg taacggtcag gcaatggcca
     7021 acaacactat gatttccgtc aattcgacaa tgacagtcgg gctatgaatg accaatcccg
     7081 attgttcggc gttgttcgga gttgcttgtt cggggcacgc ggagcggtct cgaacagccc
     7141 gggtgcggta ggcatggaac cgcgggggcg gatcacgacg ccaccgcgcc ctgctcgctt
     7201 ccgccggccc tcgtcggaga tcccatgaag tactcgcggt actgccggtc cctgctgtcc
     7261 acccccgcca ccgccgtcca tcgctacgcc gccggccacc gctcgggggc cgacatttcc
     7321 atggtcgatc tggaggactc cgttccgccg gcgcgcaagg aggaggcgcg cagacgggcc
     7381 gagggcttct tcaccctccc caccgccgcc acgacccgct gcgccgtgcg catcaacgcc
     7441 atcagcggac cggacggcct gcgcgacctg ctggcgctgc gccagtacgc ggtcaagccg
     7501 ccgctggtcc tgatacccat ggtggaatcg cgccgcgacg tcgagatcgt ggagcacgtc
     7561 ctgggcccgg agtgcccgga caccgagttc gtcgccgtcg tggagacgcc gcgcggcctc
     7621 cagcacgcgg ccggcatcgc ctcgtcctcc cgcaggctgc gggccctggt cttcggctcg
     7681 gccgactacg cgttcgccac cggcgcccgg ctcacctggg acgccctggc ccacccgcgc
     7741 ggcgtgctgg tcaacagcgc gcgggcggcc gggatcgagg tgatggacgc gcccttcttc
     7801 gaggtgcacg acgacggggc gctgcgctgc gaggcggccc tcgccaagga catggggttc
     7861 agcggcaaga tcgccgtgca cccccgccaa gtgccgttga tcaacgaggc gttctccccg
     7921 gacgacgaca ccctcggccg cgcccgccgg atcgtcgccg ccgggcggga gaacggccgg
     7981 gacatcaccg tggtcgatgg cgtgatgatc ggcatcccgt tcttcgaggc gtcccagcgg
     8041 ctggtcgagg agttcggcga cggactcccg gggccgcccg cgccgtcccc cggaagcgac
     8101 gggccgccgt ccccgagacc cgcggtcgca ctgcatcggc agccccgccc gtaccccgac
     8161 gccccacgct ccaccaccgt gacgcaggag agggaacagt gaacgacacc aaccccccgg
     8221 gccccacgcc cgagatcacc ggaccgcacc gctaccgcaa cagcgccacc atgatccgta
     8281 cggccgaccc ggcgtggctg ggcgccgcgc aggccgggct gatcggcgtg gtggccgact
     8341 cccccgacgc caacaaccgg ctcgtcaccc cggacgggca cgagttcgtc aacatgtgct
     8401 cgtgctcgta cctgggcctc aaccaccacc ccgccgtggt ggagggcgcg atcgaggcgc
     8461 tccgggagac cggcgccacc tccctggtga tgccgaccac ccgggtccgg caccggctgc
     8521 tggcccggct ggaggaggag ctcggcgacc tcttcggctg ccacgccctg cccggcgcct
     8581 cgtgcagcgc gctcaccgcc ggcatcctgc cgctgatcgc ctcgggccat ctgtccgacg
     8641 ggcaaccgcg cgtgatggtc ttcgaccggt tctgccactt ctgcatgtcg tacatgaagc
     8701 ccgtctgcgg tgacgagagc ctcgtcctca cctgtgacca caacgacctc gaccggcttg
     8761 aggagatctg ccggacgtat ccgcgggtcg cctacgtcgc cgacggcgcg tactccatgg
     8821 gcggcgcggc ggccctggac gggctgcggc ggctccagga gcggtacggc ctcttcctct
     8881 acctggacga ctcgcactcg ctctccatcc tcggcgagca cggcgagggc ttcgcccgct
     8941 cgcagctgga gatgaacgaa ctgaccgtga tcaccgccag cctgggcaag gcgttcggca
     9001 ccgccggcgg catcgccatg ctcggcagcc gggagatgtt cgagttcctg caccggcacg
     9061 cgggcccggt cggctggtcg cagaacatgt ccttcccggt cgtcggcgcc tcgctggcgt
     9121 cggccgcgat ccaccgctcc cccgaactcg gcgaactcca gcgcaggctc caggagaaca
     9181 tcgcctactt cgacaccgcc ttccccaccg ccttcgccgg aaacggcctg cccgtgcgcc
     9241 gcatcaccgt cggcgacccg gaggcggccg tcaaactctc cgccgacatg ttccagcgcg
     9301 gcttctactg ctcggcggtc ttcttcccca tcgtccccaa gggcgaggcg ggtctgcgca
     9361 tcatgatccg cgcggatctg tcccgggaga agctcgacga gttcatcggc cacatcaagg
     9421 acctctcccc cacgcactga ggacggtacc gacccatggc ggacgacgcc ccgcccagcg
     9481 gctacgagcg gctgggaccg cagcactacc gggaagtggt gggcttcctc tacgaggagt
     9541 tcaccgtcgg cgacgtgatc gagcaccggc ccggccggac cgtcaccgag atggacaacg
     9601 ttctgatgag cacgttgtcg atgaacgacg cgcccctgca catcgacgcc gcgttctgcg
     9661 cggacactcc ctggggccgg ccgctggtct ccagcctcgt caccctcagc atcgtcggcg
     9721 gcatgacggc ccgcagcacc agcggcaagg ccctggccaa cctgggctgg gaccgcatcc
     9781 ggctgcccaa cccggtgttc accggcgaca ccctctacgc caccaccgag atcctcggca
     9841 aacggctctc ccgcagccgc ccgggcgagg gcatcgtctc ctgccggacc accggcacca
     9901 agtccaccgg cgaggtcgtg ctcgtcttcg agcgaagctt cctggtgccc tgccgcgacc
     9961 ccgagcccgg cggcccggcc gccgcgccgc ggggggacgg atgacggcgc tgctgatcgg
    10021 caacaaccgg gccgccgaga tgaccggcgg cccggacggc accccggagg agcggcggcg
    10081 ggcggcccgg ggcgcccaac ggctgctgtg gtgggcccgg gacggcgacg tcctgctcct
    10141 ccctgaggcg cccgacgacg ccttcgccga ccacgtcacc ggcctcaccg gcacccgccg
    10201 ggccggcctc accgtcgtca ccgccgccct cccgcccacc ggcgccctgc ccgacgcgac
    10261 ggtcgccgcc gtccgcgcgg ccctggccgg gcggaccgtc gaccgggtga tgccggtgta
    10321 cgccgacacc ggcgtcaccg gcctcgtccg acggctcggg gccgaacggg cgctgcccgg
    10381 ctgggccttc cacgaccagg gcggcagcgc cctggtcaac agcaaggccg ccttccgcgc
    10441 ggtggcggcc ggcaccggga cgcccgtcgc cgccggtacg gtggcgggca gcccggacgc
    10501 ggcgggcgcc gccgcggcgg agctgctcgc cgccgggcac cccgccgtcc tcaagctcgc
    10561 cttccactcc ggcggcctcg gcaacgaggt cctcaccacc gatccggccg tccgcccgct
    10621 cggggcgcac cgcgccgtcg tcctccccgg cccggacgcc gcccgggagc acacggcccg
    10681 gcactgggcc gggctgtcgt cgggcgggcg gcaccccgtg gtcgtcgagc ggtaccaccc
    10741 cgaatccgtc cccgtgtacg ccgagttcga ggtccgcgac gccggggtgg tgctgtccgg
    10801 ccacggcgag atgctgatgg acccgatgct ggacggcgag accgtgcccg ccgccctgcc
    10861 gccggacctc ctggaccggc tggtcgggca cgggcggcgg ctgtgcgagg cgtaccgcgc
    10921 cctcggctac cgggggacgc tcagcgccga cgccatcgtc acccccgcgg gggaactgct
    10981 gttcaccgag gccaacggcc ggctcaccgg ctcgtcgcac ctgcactccg tgctcgcggc
    11041 gcggctcgtc ggcgaacccc tgcggtcccg gcgggtgttc ctggagaagg gcgcctggcc
    11101 ggtcccctcc ttcggcgcgg ccctcgacgc gctggaccgg gccgggctcg ccttcgaccc
    11161 cgcgacgcgc acgggcgtcg tcctcgtcgg cgaccgcgtc ccggtggacg gcacggtggt
    11221 cccctgtgtg atcgcccccg accggcccgc cgcccacgcc gtgcggcgct ccctccccgt
    11281 gttcgccgcc gagcccgccc ccgcctcctg acgaaaggcc gccgcatgtc cctgaacagc
    11341 tacgacagtt ggtccccctt gcgtgaagtg gtcgtcggct cggccgagaa ctactcctcc
    11401 cacgagcggg agctgtcctt cgacctgttc ttccacgacg agatgccgta cagccgcatg
    11461 tactacccgc gccaccgggc gccgggcggg gacgcgtccg gggaggacgg caccggcacc
    11521 ggggcccggc agagccccat caagaagcgc tacgtcgagg agctccaaga ggacgtcgag
    11581 gggatggtcg acaccctcgc ctccctcggc gtcaccgtgc accggcccgc gccgctcgcc
    11641 gagcacatcg aggtgcgcac gcccaccttc cgggccgccg tcatcccggc cctcaacgtc
    11701 cgcgacaaca gcatcgtcct cggcgacgag gtcatcgaga cggcccctca ggtgcgcgcc
    11761 cgctacttcg agacgcagct cctcaagccg gtcttcgccg actacttccg gcgcggcgcg
    11821 cgctggacgg tcatgccccg gccgctgatg accgacgcct ccttcgacct gtcctacgtc
    11881 acggcgcaca ccgcccccgg cgagctgatg gagccgatca ccgacccccg gccgtcgccg
    11941 tacgacgtcg ggcacgagat gatgatcgac ggggcgcagt gcctgcggct cggccgggac
    12001 gtcttcgtca acgtctccac cgccaaccac gtcctcggct gcgactggct ggagcgccac
    12061 ctggacgggc ggttccgggt gcaccggctg gactcgctgt ccgacagcca catcgacagc
    12121 accgtgctgg cgctccgccc cgggctgctg ctggtgcgca ccccgcagat cgccgagcgg
    12181 ctgcccaagc cgctccgctc gtgggacatg atcttcccgc cggagccgga ggacaaccag
    12241 ttcccggtgt acgacgctga cgacctcctc ctgaccagcc gctacatcga cctgaacgtg
    12301 ctgtccgtgt cccccgacac cgtcctggtc aactccgcct gcccggagct gatccggacg
    12361 ctggagaagc atcgcttcac ggtggtgccg gtgcgccacc gccaccgccg cctcttcggc
    12421 ggcggcctgc actgcttcac cctcgacacg gtccgggagg gctccgcgcc cgaggactac
    12481 ctggagggct gagcggcatg cgggctgtgg tgatccgccg gttcggcggg ccggaggtgc
    12541 tggagaccgc ggagctcccg gaaccggtcg ccggtgcggg cgagtccgtc gtcgacgtgg
    12601 tgctggcggg cgtcaacttc ggggacctgg aggtgcgggc ggggacctac cggccgccgc
    12661 ggctgcccgc ggtcctcggc gcggagatcg tcggcgtccg ccgacgggac ggccggcggg
    12721 tggccgcgct gctgcgcgac gggggcggct acgcggaggt ggccgtcgcc cgggacgcgt
    12781 acaccgtgga actccccgac gacatcgacg acctggcggg cgccgccctg gtcgagcagg
    12841 gctgcacggc gtacgccgcc ctggtcacgg ccggccggct gcggccgggg gaacgggtcg
    12901 cggtcgcctc cgccgcgggc ggggtcggac acctggccgt gcaactggcg cgcgccctcg
    12961 gggcgtccgc ggtcgccggg acggcctcga ccgcggccaa gcggcagttc gtccgggagc
    13021 tcggcgcgga ccacgcggcc gagggccccg aggcgctgcc ggcgctgttc cccgacggcg
    13081 tggacctcta cctggactcc ctgggcggcc cgcgcgtcga ggccgcgctc gccgcgctgg
    13141 cccccttcgg ccggctggtc tccatcggcc accgcgagga gccggccgtc gtcgcggtgg
    13201 acgcgctcac ccggcgctcg ctcggcgtgg tgacgctgtg gatgcggcag gtcctggaag
    13261 cggacgggct gttcgcggag gtggccggcc gggtcctcgc gctcgccggc gagggccgac
    13321 tggtcccgca cgtcgaccgg gtcgtcccgc tggacggcgt cggcggcgcg cacgaggccg
    13381 tcgccgcccg ggcgacgacc ggcaaagtgc tggtggacgt ccgggcggcg gggtgttgac
    13441 ccggggattg tgccggggac ggcggctgga taaggtcccg tcgggcccgc gacagggccg
    13501 ttgctggcac gcggtggcag gtggggaatg tctgtggtca cgggtaagat aatccgcttc
    13561 gacgaattcc gggggtacgg gttcgtcgcc ccggacaccg gcggcgagga tgtgttcgtc
    13621 cacgtcaacg acgtccaggc ggacaagcgc ctgatcgtcc ccggtgcttt cgtcgagttc
    13681 tccgtggagg agggcgagcg gggcctcaag gcgtcccacg tgcgtctgct ggaccgggcg
    13741 tccggccggc cggccgaggt cccggcggag ggctacgtcc ccggcccgtc gggcgacgac
    13801 ggcgactgcg acgtgctgtc cgccaaggag ttcacggacg aggtcaccga actcctcctc
    13861 tccgcggctc ccaccatgac cgcggaacag atcctcctcg tccgccagcg cctcgtccgc
    13921 ctggccgcca accacggctg ggtcgaggca tagacatcag gcggggcgcc gcgctcccgg
    13981 gcgcggcgcc ccggaacgaa cggaaaggac cggcaccatc ggttccgcgc actacaccgt
    14041 caccgcctac ccgaagcact ccgacttccc cgcgagcgag acggaactga cggacgccga
    14101 cccggctttc ctcgccgggc tgttcgggat cccggtcgag cggttcgtgg acgtctaccc
    14161 catggacgcc gggcacatgg cggtgctgga acggacggcc ggtctggcct tcgacccggc
    14221 cgcgtacgac tacttcctcg aggtcacggc cggctgacag cggacgggcg gccgcccgct
    14281 cacccccgcg ccggcgtcgt gagcgcgccc agcgggtcgt gtccgtggat ccacgccagc
    14341 cggtccggga gcgtggtgag gttcgcgtcg cgggcggtgg cctgggggcc gtcggggagg
    14401 tggaggcagg tggcgttctg ccgggagccg gcctggatgg cgcgggttct ggggcggcgc
    14461 gtccgttcgt agcggcgcag ggcggcgggg acgtcggtgg gcgcggcgtc ggcgagcagc
    14521 gcggcgagga cggccgcgtc ctccagcgcc tggttcgccc cctgcccgtg gtgcggcagc
    14581 atggggtgcg ccgcgtcgcc gagcagggtc acccggccgc gggtccagga ccgccggggc
    14641 tcgcggtcgt acagcgccca gcggccgggg cggtcgacgg cggccagcag gccggtcagg
    14701 gccgggtgcc agccgtcgaa cgcggccagc aggtcggccg tccggccttc cgtgacccag
    14761 gactcgacgg tccaggcggg gtccgggacg acggccagga gattgagcag ccgcccgccc
    14821 gcgaccgggt acaccaccac gtgccggccc ggtccgaccc acagccacag gacggggtcg
    14881 gcgagttcgg gcagatccgg cagccggtcg agggggacga gggcgcggta gccgctggtg
    14941 ccggagaaga ccgcctcgtc ggggccgaag accgcgtccc ggacggcgga gtggatgccg
    15001 tccgcgccga ccaccgcgtc cgcctcggcc gccgagccgt cggcgaagcg gacgacggcg
    15061 ccgtcggggg tctgctccac gccggtgcag cgggcgccga agcgcaccgg tatcccgtcg
    15121 gcggcggcga gcagcgcgtc ctgcagggcg gagcgttcga ggtgccagaa gggggcgccg
    15181 aaccgccgct cgtagccgtc gccgacgccg agcccggcca ccgtccggcc cgtgcgccag
    15241 tgccggaagt cgacgcgcga cggggcgacg gccgtcgccg cgagccgccg gtcgacgtcc
    15301 agggagcgca gtacgcggtg gccgttggcg ccgatggcga cgcccgcgcc ggtggccgtc
    15361 ggctccgccg cctgttcgtg cacgacggcg tcgagtccgc tccggcgcag cgcgacggcg
    15421 gcggccagtc caccgatgcc cccgccgacg accgcgatgg tgggccgtct tccggccatg
    15481 gtccgctccc tcccgcccgg cggtccggtc cgcggtccgc ccggacgccg agcctaccca
    15541 cgggtcgacg ggccgcgcac gggttcggtt ccggacgatc agccgaccct gcgcgggagg
    15601 tggccgcgag tggcgggttt ccgacaggag ttggcatatt atcggaagcg ggacgcgcga
    15661 gggagccgtc acgatcgggg ggtgccgaag aaccgatccc tcaccttccg cgaccgcccg
    15721 atcctgctgc tgtccacggg gcacgcctgc gtggacgtct accagggggc cgtcgccgcc
    15781 ctggtcccgt tcttcgtctc ggagcgggcc tacacctacg ccgccgcctc gggaatcgtg
    15841 ctggccgcct ccctgctgtc gtccgtggtg cagccgctgt tcggggcgct caccgaccgg
    15901 tgggccatgc cgtggctgct gccggtgagc accctgctgg ccggggcggg cgtcgccctc
    15961 agcggcctgg gcggctcgta cgccctgacc ctggcagtcg tcgccgtgtc cgggatcggc
    16021 gtggccgcct accaccccga gtccgcgcgg gtggcgcgcc gggcgagccg gggcagccat
    16081 gtggcgatgg gctggttctc cctcggcggc aacctcggtt tcgccgcggc cccgctgctg
    16141 gtctccgccg tcgtcgccac cggcggcctg cgcgcgacgc cgctgctggc gctcccggcc
    16201 gtcgcgggcg cggccctgtg cgccgccgcg ctgcgcatgg cccgcgcgcc gggggacgcg
    16261 ccgggcgccc gggccgcgtc ccgcgcggcc ggccgggacg actgggcgtc gttccgccgg
    16321 ctgaccggcg ccatcatgtg ccgttcggtc gtcttcgtcg gcctgagcgc cttcgtctcg
    16381 ctgcacgtcc gccagcgcac cggctggggg caactggccg gtacggcggc cctgttcgtg
    16441 ctctatctcg gcggcgcggt gggcacggtg gcgggcggga ggctggccgg gcggtacggg
    16501 cggacgacgg tcgtccgctg gtcgtacgcc ctggcggtgc cggcggtcgc gggcgtcgtc
    16561 ctcgtccccg gcccggcgct ctacctgttc gtggccctga cctcggccgc gctgtacgtc
    16621 ccgttctccc tgcacgtcac gctcggccag gactacctgc cgcgccgggt gggcaccgcg
    16681 agcggcgtca ccctcggcct ggcggtcagc gtcggtggcg tcgcgagccc gctgatcggg
    16741 gccctcgccg acgtcacgtc gctgcgggtc gccctcgcgc cgctgatcgc gctgcccgcc
    16801 gtcggctggc tgctgctgcg cccgctgcgc gagcccggcg cgccgggggc gccccgcgtg
    16861 cccggcgcgg cgccggcggc cgatgccccg agcgcgcccc gggaggtgtg agccgcgtcg
    16921 ttggacgccg ggcgccgtgg tgcgcgagag tggtccgaga cgtaatgatc aaggaaggga
    16981 cagtgccgtg gcacaggaag tccggggcgt ggtggcgccg gggaagaacc agccggtgcg
    17041 ggtcgagacc atcgtggtgc cggacccggg acccggcgag gccgtggtga aggtccaggc
    17101 gtgcggcgtc tgccacaccg acctgcacta caagcagggc ggcatcaacg acgacttccc
    17161 gttcctgctg ggccacgagg cggccggcgt ggtcgaggcg gtcggcgagg gcgtgaccga
    17221 ggtcgcgccc ggcgacttcg tcgtcctcaa ctggcgcgcc gtctgcggcc agtgccgggc
    17281 ctgtctgcgc ggccgcccgc agtactgctt cgccacccac aacgcccggc agaagatgac
    17341 cctgaccgac ggcaccgagc tgacgcccgc cctgggcatc ggcgcgttcg cggagaagac
    17401 gctggtcgcc gccggccagt gcaccaaggt cgaccccgag gtctcccccg ccgtcgccgg
    17461 gctgctcggc tgcggcgtga tggcgggcat cggtgccgcc atcaacaccg gcggggtgag
    17521 ccgcggcgac tcggtggccg tcatcggctg cggcggcgtc ggcgacgcgg ccgtcgccgg
    17581 ctcgcggctc gcgggcgcgg cccggatcat cgccgtcgac atcgacgacc gcaagctgga
    17641 gacggcccgg cggatgggcg ccacccacac ggtgaactcg cggaccaccg acccggtcga
    17701 ggcgatccgc gagctgaccg gcggcttcgg cgccgacgtc gtcatcgagg cggtcggccg
    17761 cccggagacg tacgagcagg cgttctacgc ccgcgacctg gccggcaccg tcgtcctggt
    17821 cggcgtcccc acccccgaca tgcgcatcga cctgccgctg ctcgacgtct tcggccgcgg
    17881 cggcgccctg aagtcctcct ggtacggcga ctgcctgccg tcccgcgact tccccatgct
    17941 cgtcgacctg cacctccagg gccggctgga cctggcggcg ttcgtcaccg agaccatcgg
    18001 cctgggcgac gtcgaggcgg ccttcgaccg gatgcaccag ggcgacgtgc tgcgctcggt
    18061 ggtggtgttc tgatgccggc ccggatcgac cacctcgtca cctcgggcac gttctccctc
    18121 gacgggggca cgtgggaggt cgacaacaac gtctggatcg tgggcgacga ccacgaggcg
    18181 atcgtcatcg acgcggcgca cgacccggac gccgtcgccg aggcgctcgg cgaccgccgg
    18241 ctgctggccg tcgtctgcac ccacgcgcac gacgaccacg tcaacgcggc accggcgctg
    18301 gccgaccgca ccggcgcccc ggtcctgctc caccccgacg accggcccct gtgggaccgc
    18361 acccacccgg accgcgcacc ggacggcgag ttggcggacg ggcaggtgct gcgggtggcc
    18421 ggcacggagc tcaccgtgct gcacacgccg gggcacgcgc cgggcgccgt ctgcttgcac
    18481 gccccggagc tgaacacggt gttcaccggg gacaccctct tccagggcgg cccgggcgcc
    18541 accggccggt cgttctccga cttcccgacc atcgtcgcgt cgatccgcgg ccggctgctg
    18601 accctcgacg gcgacacggt cgtccggacg ggccacggcg acacgacgac gatcggcgcg
    18661 gaggccccgc acctggagga gtggatcgcc cgcggccact gagccgcgga agacttcggg
    18721 cacgcgccgg ccggtgaccg gaccggtcgg cgcgcctagg atcgcaagcg tcgcggggcg
    18781 cgcccgcggg aacgggggaa ggatccatgg acatgacgga cctggtggag atcaccgagc
    18841 ccggcgagct gacggagctg ctgggggaac cgctcccgcg cgtccgcgac aaggcccgtg
    18901 accggctggg cgagttggac cggcagtggc tggagcactc gccgttctgc ctggtggcga
    18961 catcggacgc ggacggcaac tgcgacgtct cccccaaggg cgacccggtc ggcggcctga
    19021 cgctcgtcct ggacgacacc accctcgcca tcgccgaacg cccgggcaac cggcgggcgg
    19081 acggcttccg caacgtcctc gccaaccccc atgtcggcct ggtcttcctg gtgcccggcc
    19141 gcggcgacac cctccgcgtc aacggccggg cccggctggt gcgcgaggcg ccgttcctcg
    19201 accggatgac ggtcaagggg caccgcccgg tcctcgccct gctggtcgag gtcgaggagg
    19261 tcttcttcca ctgctcgaag gcgttcctcc gctccgagct ctggaagccg gagacctggc
    19321 ggccggacga ggtcccgtcc cgggcgcgca tcgccaaggt gttggagcgg cccgaggact
    19381 ccatggagga gttggagacc tactacgggc cgcggtacgc cgagcgcctc tacggctgag
    19441 caaacagatt gtttacaaca cgtcattggc accccgtcat gtggtgcggc acgctgctgc
    19501 gtatgccgtc atcttccgag gcgccgaagg cgtctgatgc ttcccggacc cccgacccct
    19561 tctctccccc ggacctcgac caggcgcggg cgcggcgcgt ccacgcctcg ctgttccgga
    19621 tcgccgagcg gcacgcggac acggaagcgc gccgccgtcg gcagacccac cccacgatga
    19681 tcggcccgca cgaggccgtc cggctggtgt ccttcctgct cagcggcgcc gccctgctgg
    19741 aggacggcga accggaggtg gaccgcgccg acatcaccgc cgccctgagc ctcgtgccgc
    19801 tgatgcgcgg ggagatggac gagctggagg ccgggctcct cggaatggcc cgggggcgcg
    19861 gcatgacctg gccggacatc gccttcggac tcgggctcgg cactccccag gccgcacggc
    19921 agcgctacga acggctggcc gaccgtacgg cgcgggacga gtgacagccg tacgccgcga
    19981 ggccgtcgag ggccgccacg accgtcatcc ggcggacgcc gcggcccgca gcgcgttctt
    20041 gtcgatcttt ccggtggcgt tgcgcggcag ggccgccacc gtccccaccg acgtggggca
    20101 cttgaacccg gcgagccgct cgcggcagaa cgcccggagc tccgccggat cgaccggcac
    20161 cccgtcggcc gtcaccagga cggcccgtac cgtctcgccc cacttctcgt ccggcacccc
    20221 gatcacggcg gcctcgacga cggcggggtg ctcgaccagc acccgttcga cctcggcggg
    20281 gcagacgttc tcgccgccgg tgatgatcag gtccttcagc cggtcctcga cgaagacgta
    20341 gccgtcctcg tcgatccgcg ccaggtcccc ggtgcgcagc cagccgtcgt cggtgacggt
    20401 ctcggccgtc gcggcggggt tgccgaggta gcccttcatc cggccggggg accggatcca
    20461 cagttcgccc cgccggcccg gcggcagttc ggcgcgggtg gcgggatcga cgacgcgcgc
    20521 ctcgacgccc ggcatcgggc ggcccgcgga ggcgaggcgg tgggcatggg cggggtcgcg
    20581 gtgggcctcg ggggccaggg cggtggcggc gccggagagt tcggtcatgc cgtagagctg
    20641 gaggaaccgg atcccgggga acagcgcgag cgcccggcgc agcaccggca gcggcatggg
    20701 cgatgcgccg tagaggcagt accggagccg gccgaaggcg gcgaccgcgt ccgggccggc
    20761 cgccaggatg ccgggcagca tggcgggcac cagcagcagg tgggtggcgc cgtcggcgac
    20821 ggccgcgcac atggcctcgg gggttgcctc gcgcagcacg accgtgggcg ccccggcgag
    20881 cagcgcggtg acgacgtagc agacgccgcc gacgtggaag aacgggagga cggcgacgct
    20941 gcggtcggcc gggcccatag aaaggacggc gagcagcgcg gcgctctgct ccagcaggcc
    21001 ccggtgggtc agttcggcgc ccttggggga tccggtggtg ccggaggtgt agaggatgac
    21061 gcaggtgtcg tcggggtcga ggtcgtcccg ggcggcgagc ggttcggcgg ggtccagcag
    21121 cgcggcgtac gtctcggcgc cgtcggccgg cccggcgccg tcgccggtga cgaccaggcg
    21181 gggcggggcg tccagcgtgc cgagggcggt gcgtacggcg tccagcacag cggcgtcggc
    21241 gaacaggacc gtggcgccgg agtcggcgat gacatgggcg agttcgggcg gggcgaggcg
    21301 ccagttgagg atcgcggtgg ccgcgccggc gccggcggcg gcgaggacgg tctccaggca
    21361 cgcgaggccg ttccggccga cgaccgcgac ccggccgccc cggtccacac cggcggtgcg
    21421 cagggcgccg cgcagcaggt cggcgcggga gcggaggtcg ctccaggtga ggcgggcacc
    21481 gccgcagacg agcgcttcgg cgtccggcgc gcgggcggcc ccgcggtcgg gcaactcgtg
    21541 cagcaggcgc gggcgttgtg cgagcggtgt gggcatccgt tccccccggt cggcgctccg
    21601 ggcagcgtac ccgcgggccg gtcggtccgc caccggcggg ccggggcgga acacgcccgg
    21661 cccgccggcg cgcggcccgg tcaggtaccg ggcttgcggc cgtagacgaa gacgtcgtcg
    21721 cccttgtgga gcaggttcca gtacgcccgg gcgtccttca tccgcatgtt gacgcagccg
    21781 tgggagccgg gcggcgagta aacgctgccg ccgatggcgt ggaacgcctg acccccgtcg
    21841 aagaactggc tgtacggcat gctcacgtcg tacagcgacg agcggtggtc cttgtcgcgc
    21901 cagtagacct tcttgaggcc ggtgcgggtg gcgaagccct ttctgcccga gcgtatgtgg
    21961 accgggccgt acttgatctt cttgccgtcc tgtatccagc tcacctggcg ggtgaggtcg
    22021 acgcaggcga tacggccctt gtccgtcggg caggagacct tggcgggcgc cttggccggg
    22081 gccttggcgg gagcggcctc ggcggtcccg ccggccgtca cggccagggg gacggccagt
    22141 ccggcggcgc ccaggaccac gcccagccgg gtccgcagag gggtgcgttt cattgtcatg
    22201 aacggtaaga ccatcgaaat ccccacttgg ttgcataccg cacccggcgc ttcggacccc
    22261 gcgggccggc ggaacccgat cttcctccgg ccgacggtcg accagccgcc cacctggggt
    22321 taggctcgtc cgggcgacgg cgcgaactcc cttgcacacc gcggcccttg ccgctccccc
    22381 gtgcactccg cctgcccccg tcgacctcgt cgacaccttc cgttccccga cccgtcgccc
    22441 tccatccgtc ccccgttccc cagcaccagg acctccttgt gaccatcccc cc
//
