LOCUS       NZ_CP040417            27744 bp    DNA     circular CON 23-APR-2024
DEFINITION  Dolosigranulum pigrum strain KPL3077 chromosome.
ACCESSION   NZ_CP040417
VERSION     NZ_CP040417.1
KEYWORDS    RefSeq.
SOURCE      Dolosigranulum pigrum
  ORGANISM  Dolosigranulum pigrum
            Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
            Dolosigranulum.
REFERENCE   1  (bases 1 to 1957024)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Eslami,S.M., Gao,W., Bomar,L., Fernandez Escapa,I., Roberts,R.J.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     The nasal commensal Dolosigranulum pigrum exhibits stable synteny
            and highly similar strain circulation over a 20-year span
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1957024)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2019) Microbiology, Forsyth Institute, 245 First
            Street, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-AUG-2018
            Assembly Method                   :: HGAP v. 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 351x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017655765.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 02:25:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,875
            CDSs (total)                      :: 1,806
            Genes (coding)                    :: 1,779
            CDSs (with protein)               :: 1,779
            Genes (RNA)                       :: 69
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 27
            CDSs (without protein)            :: 27
            Pseudo Genes (ambiguous residues) :: 0 of 27
            Pseudo Genes (frameshifted)       :: 12 of 27
            Pseudo Genes (incomplete)         :: 15 of 27
            Pseudo Genes (internal stop)      :: 6 of 27
            Pseudo Genes (multiple problems)  :: 6 of 27
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:08:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1875882
            Orig. end                         :: 1903626
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040417.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
FEATURES             Location/Qualifiers
     region          1..27744
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="7"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..27744
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27744
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:17744](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17744
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     CDS             complement(831..947)
                     /gene="allorf_1876713_1876829"
                     /locus_tag="allorf_1876713_1876829"
                     /protein_id="allorf_1876713_1876829"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIHLLHIYCHVRTLSNAPFGYYTIHLFLSLFIYRCLKS"
     CDS_motif       complement(888..947)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIHLLHIYCHVRTLSNAPFG"
                     /locus_tag="allorf_1876713_1876829_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(831..887)
                     /prepeptide="core"
                     /locus_tag="allorf_1876713_1876829_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="2226.7"
                     /monoisotopic_mass="2225.2"
                     /core_sequence="YYTIHLFLSLFIYRCLKS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIHLLHIYCHVRTLSNAPFG"
                     /leader_location="[887:947](-)"
                     /alternative_weights="2244.7"
                     /alternative_weights="2262.7"
     misc_feature    complement(1078..1092)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.38"
                     /tool="antismash"
     gene            1096..3150
                     /locus_tag="FE328_RS08995"
                     /old_locus_tag="FE328_08895"
     CDS             1096..3150
                     /EC_number="5.6.2.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013311.4"
                     /locus_tag="FE328_RS08995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08895"
                     /product="DNA topoisomerase"
                     /protein_id="WP_208957988.1"
                     /transl_table=11
                     /translation="MKTVVLAEKPDQGRKLAKALGKQKSKTKGSIDVASSILEGDVSVT
                     WGIGHLVTLSEPDDYADKYKQWELEDLPILPDQMKYKVSKGKAGQFKTVKNLLKQADRI
                     IIATDPDREGENIAYSIFKLCGREVWQIPKKRLWINSLQSKEIQRGFKELREAEETYSY
                     FKEAETRQVSDWIIGMNFTRFLTLIMQKRGIDGVWSVGRVQTPTNTLICENFLERKNFT
                     PEPYWQLKGYHILDDGQVKFSEPRKDNKFFDKNKLEQYIQQYKLNNVEEATVDSVEKTK
                     KSKSAPKLFSLGGLQSYCSSQFGWTASKTLKVLQKLYDSGYSSYPRTSSQLITTNEFNY
                     LFDNIDSYKDWLDIDFEVAYSNPRKRFVDNKKVKEHYAIIPTDEIPSRLSGDQKKLYEA
                     IVKRTLLMFAADYEYELTVVLVKANDVVFKTTGTTPIQLGWRDIESEDKDNNNDNSTLP
                     EYQQREIIPFKVRVEEDETKPPKQLTEAKLVGDKGLMKKLGLGTEATRSGIIETLKYRK
                     YIENDGKTKLKPTKKGLLLYKITKYVLVGSPEMTAKWEAYLEQIGQGNKSPDPFIKRVK
                     ESIKPTFVELNDNEAGTEAVQSVKTQNLEEIGNYQVRTKNKLFEVTPEGASEYFPLWRN
                     IAGAYMSKSDMRDLLMKGKTSKKKKMKSKKGNEFKAYWVLKNQRVEFEF"
     misc_feature    complement(1128..1147)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 19.39"
                     /tool="antismash"
     gene            3540..4496
                     /locus_tag="FE328_RS09000"
                     /old_locus_tag="FE328_08900"
     CDS             3540..4496
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /locus_tag="FE328_RS09000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08900"
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="WP_208954526.1"
                     /transl_table=11
                     /translation="MKKKKKLVSVSALLMLTSAIIGVSTVSASSDETGNINQPALYTVQ
                     EGDNLYRISQRYNISIEELKQLNALGEAYMLHPGDQLKIKRNQSNSDKKVYEVKAGDSP
                     YKIAQKFGVTVADIYQWNHIDAGTMLYPGNTVVVSGGTKQTTDTAEKGIDRIHEVTNNK
                     YNSDSYEIRVERKQADHAVIYSLADKTPEKLTVFKWFKYDTATDRVFESTDAAPKSWMR
                     LHDGEPVASIEQTGQEKALSEEGIRKVHDLTDYAYNTENYFITSEVIDEHTVKFDVSDD
                     SAEKITPIKAFKYDAKTGKVYVQEIEDRAAAKWEIIN"
     gene            4507..6285
                     /locus_tag="FE328_RS09005"
                     /old_locus_tag="FE328_08905"
     CDS             4507..6285
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013954.4"
                     /locus_tag="FE328_RS09005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08905"
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="WP_208954527.1"
                     /transl_table=11
                     /translation="MGKQQIKHSAIKVLATLLLSSGYLLIGDKIYAQEIDENISQNENN
                     DLDRIEEREISQDIVRETKIKEDYDNGVDDNIIDSKESTHEKDTIIVQSESAHSESTHS
                     MEDDGLNSANLDTANSSQNEKEFNPVSTITEEEINEIITVRRSRSKRSLNNFQREFLNK
                     IKPGAIAGWHKYKILPSITAAQGILESGWGRSDLATIGNNLFGVKGSYQGNTINMNTRE
                     ETPTGKDYYINAGFRLYPSWAASIEDHGKFLNENSRYRKLIGETDYRTVAHLLQRAGYA
                     TAGNYASSLIGLIESNKLSLWDQEAFSGRKLSPTVSSTLSGNSSKQVYTVVSGDSLWGI
                     ANKNGITLDQLLQWNNLNRNSIIHPGDNLFVSSTKNNVVSSTTSHTSTASSNKQPTAKG
                     KTYTVVSGDSLWGIANKNGITLDQLLQWNNLNRNSIIHPGDNLFVSSTKNNVVSSATSH
                     TPTPSSNKQPTTKGKTYIVVSGDSLWGIANKNGITLDQLLQWNNLNRNSIIHPGDNLFV
                     SSTKNNVVSSATSHTPTPSSNKQPTTKGKTYTVVSGDSLWGIANKNGITLDQLLQWNNL
                     NKNSIIHPGDTLLINK"
     gene            6526..6846
                     /locus_tag="FE328_RS09010"
                     /old_locus_tag="FE328_08910"
     CDS             6526..6846
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015038.4"
                     /locus_tag="FE328_RS09010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08910"
                     /product="transposase"
                     /protein_id="WP_208954528.1"
                     /transl_table=11
                     /translation="MYVKTRNYRTHLKPLLDKFTEWLDHHQYLTKAKLGKAIIYARKML
                     PSVYLLLDHAGLSISNNSAEQAMRIPALGRKNWLFSQSIKGAIANGYFLTVIQTAIANG
                     LD"
     gene            complement(6883..7782)
                     /locus_tag="FE328_RS09015"
                     /old_locus_tag="FE328_08915"
     CDS             complement(6883..7782)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /locus_tag="FE328_RS09015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08915"
                     /product="IS3 family transposase"
                     /protein_id="WP_208958339.1"
                     /transl_table=11
                     /translation="MERPSRRQQSRIAFELTEDHFRLKDVLMVIDLPASTYHYYMGQKA
                     NDPKDHPLEQLIQKIFNDSNETYGYRRITLTLRNMGYCVNHKRVQRLMQKLGIKCIKFF
                     RKSRRYNSYKGKVGKVASNRVNRRFMTSVPLQKLVTDVTEFKCLKDEKLYLSPIMDLYN
                     SEIIAFKIAKRPTLDIALEPLTEAISRIERHAPYRTTIHSDQGWHYQHHAWINCLKEHG
                     IYQSMSRKGNCLDNSPMENFFGLLKQEMYYGQDKVPFNDLKCRIENYIHFYNNDRIKVK
                     LSGLSPVNYRKQATQSHA"
     gene            complement(7746..8294)
                     /locus_tag="FE328_RS09020"
                     /old_locus_tag="FE328_08920"
     CDS             complement(7746..8294)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /locus_tag="FE328_RS09020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08920"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_201710987.1"
                     /transl_table=11
                     /translation="MSKTYSYQFKLNIVQAYLDGPLGYRLLAKKYDVSSEQLIQNWVNQ
                     YQLYGEAGLKRKKTKKKYTLRFKLNVLNFKLETGASYKETANAFGIGEPSIIANWKRLF
                     MEGGVQSLNKPIGRPPKMPKSSRSSNQKTTQSKQKTDQIARENAQLREENNLLKIELAY
                     LKKLRERGLSDPREDNNQG"
     gene            complement(8371..8640)
                     /locus_tag="FE328_RS09025"
                     /old_locus_tag="FE328_08925"
     CDS             complement(8371..8640)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /locus_tag="FE328_RS09025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08925"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_208954531.1"
                     /transl_table=11
                     /translation="MIGQKIKDRREYLNLSQRELAEGLCTQALISKIEQGKIKPSSKII
                     QQLSNRLQVPTSYFFRENSNHKSSDVQNFEENQNLLNYKNSYEI"
     gene            complement(8713..9306)
                     /locus_tag="FE328_RS09030"
                     /old_locus_tag="FE328_08930"
     CDS             complement(8713..9306)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="FE328_RS09030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08930"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_208954532.1"
                     /transl_table=11
                     /translation="MKVLIIDQHCFSGKCIFTALTQANTIDTFYFHEPSHDLINKIILL
                     DIDIILLVIHLETLNEFKLAKKIIDETRSKLCFMSALDLLEFKQIAYDIGAFAFFNETI
                     DIDTLITQLKKIHNQSSPSYIINDCRHVLTSQEKLILEKLANGETQKSIAFDLGITTRT
                     IRNHLYSINKKLDTQSTIQAIVKAHSLGIIYFNL"
     gene            9463..9660
                     /locus_tag="FE328_RS09035"
                     /old_locus_tag="FE328_08935"
     CDS             9463..9660
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS09035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08935"
                     /product="hypothetical protein"
                     /protein_id="WP_208954533.1"
                     /transl_table=11
                     /translation="MKQSDKDTVQGNKEHLVEKNFKIYDEVTDEDLQENGGVAWTSLVP
                     ISLAICPSTKCASITRPCNK"
     CDS_motif       9463..9573
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKQSDKDTVQGNKEHLVEKNFKIYDEVTDEDLQENGG"
                     /locus_tag="FE328_RS09035_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9574..9660
                     /prepeptide="core"
                     /locus_tag="FE328_RS09035_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.70"
                     /molecular_weight="2834.4"
                     /monoisotopic_mass="2832.5"
                     /core_sequence="VAWTSLVPISLAICPSTKCASITRPCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKQSDKDTVQGNKEHLVEKNFKIYDEVTDEDLQENGG"
                     /leader_location="[9462:9573](+)"
                     /alternative_weights="2852.4"
                     /alternative_weights="2870.4"
                     /alternative_weights="2888.5"
                     /alternative_weights="2906.5"
     gene            9672..9869
                     /locus_tag="FE328_RS09040"
                     /old_locus_tag="FE328_08940"
     CDS             9672..9869
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386877.1"
                     /locus_tag="FE328_RS09040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08940"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_208954534.1"
                     /transl_table=11
                     /translation="MNKDFDKELLNISGNLKEELSEADLEQISGAGVGKWIRKLSKGNT
                     GKVCTLTWECGICPSHTCFL"
     CDS_motif       9672..9764
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNKDFDKELLNISGNLKEELSEADLEQISGA"
                     /locus_tag="FE328_RS09040_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9765..9869
                     /prepeptide="core"
                     /locus_tag="FE328_RS09040_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.80"
                     /molecular_weight="3616.3"
                     /monoisotopic_mass="3613.9"
                     /core_sequence="GVGKWIRKLSKGNTGKVCTLTWECGICPSHTCFL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNKDFDKELLNISGNLKEELSEADLEQISGA"
                     /leader_location="[9671:9764](+)"
                     /alternative_weights="3634.3"
                     /alternative_weights="3652.3"
     gene            10001..12952
                     /gene="lanM"
                     /locus_tag="FE328_RS09045"
                     /old_locus_tag="FE328_08945"
     CDS             10001..12952
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="FE328_RS09045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08945"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_208957989.1"
                     /sec_met_domain="DUF4135 (E-value: 6.8e-83, bitscore:
                     275.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.2e-48, bitscore:
                     161.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSSFLEVKESTKKLLFQDLKGSNIDEIYQDFDINSINQTRESIL
                     FIFNEEQKKKNEKQFEYTAYKNLGNFSTYFCQYFLTQFDLYSNEYIEEIEDIEFFKKNL
                     TDQLSNKILKISYRTLIYEMNVMRKENMFESTLKDEQYLEFCNKLKDSTFVKEILLKYP
                     VMDYLVYTTITFFKEFIFEIVKHFKNDKSILVQNTLIIEEDKIKCMILGQGDSHNKGKT
                     VVKIKMSTGKTLYYKPRNLEVDLLFNKVIQLLSEKENIDLCTYGVCSLENHGWVEEVEY
                     KPVKTLDELFMFYKNMGSLLAILYALNAVDIHIDNIIANGEIPMLIDCESLFHSSEYHE
                     EEDNATRYLNNYLSQSVLSIGVLPFIFGTGSTDISALSDQKNKKTSIKVPTIKNSNRSN
                     MKLVREYVTMEESKNNPNANDLKISEEEKEKNILEGFELGYHAVLSCRKQILHLIDRSN
                     DKMILRHIIKPTLFYSNLIEISNHPSILIDFELLELLFARIQDEEHSKKINQEEFKDLL
                     QRDVPYFFSCFKDKDLYKNGEVIEKNSFTESKYSIFIRKMNMLSIEDKERQMDLIKSRL
                     SISRFNQDQYNLKSFKENNAIDLNTKKQFIIDRAIKIGNEVINSAVKYNNTYSWLSYQL
                     IGEVGAPSFLSINEMDYNLYDGLAGQGIMLLALFLQTNDNKYKKMLNAIIDDILNNVQT
                     LKGCPLGAFSGGYGIIYLLALYCKKVEERDTYIDKLLFLIESSLDELKTVEEYDIISGF
                     AGILLILTNLYCNNIKSTSVVKAMDICVKYLIDGVTTDKNKYIGWKQSEGGEILTGFSH
                     GIAGITYSLQKYQELSMNSINQSEVINKIIKETREFQAKSKNNGKFIDLRKESYNNIPY
                     AWCHGLPGIICSGEQDYQTKQNLIDMTENAFGRNHCLCHGDLGNLIILSEFNKDQNWIV
                     DYAYHICTTETLFSGIGISDLSSDEFMVGNSGICWGLIYLFNNNLPNVLKLEI"
     gene            12970..15051
                     /locus_tag="FE328_RS09050"
                     /old_locus_tag="FE328_08950"
     CDS             12970..15051
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="FE328_RS09050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08950"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_208957990.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 8e-27, bitscore:
                     90.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTPIILQKNKYECGLAALAMLFSYKDKKIDISFLKKDKQEIIGR
                     DGLSLADLKKIAKTNAGNLRVFKVYDITKYLDTYEITQPLLCYINNSHYIVVTCKKKDR
                     IWVNDPQVGRYNISEQEFSNLFSGYIAILEKNKKNKDIFEFSSKKNARLFSYITTHSSV
                     VIQLIFWTLVFQVLNILFPAMIQKIIDQEINITIFSLFMILGLSIVYYLISKYQLKLAT
                     KLQIIINKLLTIDFVKKVFSIKSSFIEINSIGYFTNSLSNINTIKEILVSLSTLIVINV
                     TLMLIYTIALIYFSPILTLIVYGFVIMQGIVLWKAAPKIRDFIGGEIKNNIDFQNYYIE
                     SLKNYNNIKSMGDPKYVVNFILDKFTGQLHSFEKRMDIQIKLTSFLGTVQWLLPFIVLI
                     AGYLLMDSINLTMGSLVAISAIALRIVTPLASASEVYQSILMMKEIFENIDNVLTQPEE
                     NADKGNSIDTMPFPIKFNDIGFSYGNTEIFKNITLNIERNDKIIIKGKSGEGKTTLLKL
                     LTTLYAPTVGKIYFGGKELKNYKLNHIRSKIGYMSQDYSLISGTIMDNITMFDDRISLK
                     DVEKAAQLVCIDEFINQMPMNYYTFLNSNGSSLSGGQIQRICLARAIVRNPELLVIDEG
                     TSNLDKDLERKVIRNLFNLNCCICIVSHRHNEIDGINKEIVINNNSLLIKKYNKGDIN"
     misc_feature    12985..12998
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.26"
                     /tool="antismash"
     gene            15048..17744
                     /gene="lanM"
                     /locus_tag="FE328_RS09055"
                     /old_locus_tag="FE328_08955"
     CDS             15048..17744
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="FE328_RS09055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08955"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_208954540.1"
                     /sec_met_domain="DUF4135 (E-value: 2e-61, bitscore: 205.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3e-29, bitscore: 98.6,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTNKLTSLFIKENYLNSIDDNIQVIIEGEQTFLNKDKISKTLY
                     EYFYNTIYEVSIKQLLKWFHSSFDYIDETDKQYNINKFISFKPFYSTREFLILDKLIVK
                     IIENKTNFAKEVISNFQKSYENIKSKYRLGESINLCIEDLIFEVGDLHNSNKSSCVIIT
                     NQKLKLVYKPRTAANDKFFYEIVNFLENHLNLVQTEYPSLIISEATFSIFPFIDKQELT
                     DNAEAEEYYYRLGISTMVLYVVGATDIHFENIMSNKQFPIFIDLETLFDVTKIKIQEES
                     NEFNSELLQSVLTSHIFDYSLNPNQTDIVGIGGYTTSVNLESEEKLINKDTDEMHLSFI
                     QTKKDIFNVPRLANCFLEITEKKTQFIKGFYDAYNIILRHKNYLKKIIKDYSSSIILRT
                     LIRPTYIYHNYRRKILEDLTIIHKNERLWKKLEQNSMVNKEIINLEKRALTRYDIPFFY
                     CIMNGCSLCSEGARVEGFLPITPLEYYLNKLEKITTEDCLVQLWYLNQSIEIYNNYLFK
                     KINTENKNDIKMYLERRIGAHLAEDVSFCSIKMCYNSDIVLSPMNYDLYDGLYGLKFMD
                     KIFSERYNVHLIRDRNKIQNIIDKLSKINLANFSAYSGQFSQLKYNLLKFEISNSNIDF
                     KNDWITYSQLVEKINKLSTPNIDFLNGISGIISLMIELYHKTKDERIIIDIERTSNFLW
                     EEYQESPIQNSIISFAHGAIGIEYVFSKVVPLLSDDSKIKQKLIRHLDEKLTEIRNYIQ
                     HVIINETEINYTWCNGLTGFLVAWLAINKHLNCQFSELEKKLINKYIDNYTFKMLDDSI
                     CHGHAGNLLSLNYILDRNLNKGYRRGDLIDLKIQIERCLQNKIMYNKICSGYEYKDIKS
                     FSLFLGDLGVYASYILSTEGISSSILY"
     gene            17763..18623
                     /locus_tag="FE328_RS09060"
                     /old_locus_tag="FE328_08960"
     CDS             17763..18623
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="FE328_RS09060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08960"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_208954541.1"
                     /transl_table=11
                     /translation="MLSMQSISKKYGELYALKDAELEIKKGEMVALIGNNGSGKTTLMK
                     IISGITKASTGTFEWETNRQTNLIETPEFFDYLSGYKNLEYFRIQRGIQDQHIIEDILE
                     RVGLPNDRKKFKQYSLGMKQRLAIGLCLLGNPEFMVLDEPTNGVDAQGIIDIRNLLLTL
                     NKEEQLTMLISSHNINELYNIATRFVFIKSGEIKKDISKSELNENIGTFYQVNIGRIQD
                     IEALINDTVLQSNYYTIDDKNTLKLVKNFETSQFIEQLSQKELIDDISEVQVTLEDYYL
                     EIMKG"
     gene            18631..19386
                     /locus_tag="FE328_RS09065"
                     /old_locus_tag="FE328_08965"
     CDS             18631..19386
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS09065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08965"
                     /product="hypothetical protein"
                     /protein_id="WP_208954542.1"
                     /transl_table=11
                     /translation="MVKKYIYSELYRIKHIRMYIALFFITILFPIATTAFLSIISLQQT
                     EPTTKEFGLYSLYMLIFIGLYLAYPIVICANTVKPKYVERQILSSGITKNILYFSDLFY
                     INIIQLIMLVLYSVSSIISTTLLLESAPGAEDSLDLVTVKEFIIIMCCIYITMILSSIV
                     LYSLQLVLSNKIFATGLFMFLVYVIPLVIAQIRYFSDIADSVAQIIPFLQVAFFYKGDS
                     PLSMLLLIHGIWIAVTIMICNTIYNKIEA"
     gene            19413..19595
                     /locus_tag="FE328_RS09070"
                     /old_locus_tag="FE328_08970"
     CDS             19413..19595
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS09070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08970"
                     /product="hypothetical protein"
                     /protein_id="WP_004636946.1"
                     /transl_table=11
                     /translation="MKESLFFVSLLFLAVFLILGVYWLTQRWVYDVDVRGLRKWILTSF
                     VLYAITYGISLYLIN"
     misc_feature    19811..19831
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.95"
                     /tool="antismash"
     misc_feature    complement(19812..19832)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.44"
                     /tool="antismash"
     misc_feature    complement(19943..19957)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 18.87"
                     /tool="antismash"
     gene            <20098..20589
                     /locus_tag="FE328_RS09075"
                     /old_locus_tag="FE328_08975"
                     /pseudo=""
     CDS             <20098..20589
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013311.4"
                     /locus_tag="FE328_RS09075"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08975"
                     /product="DNA topoisomerase"
                     /pseudo=""
                     /transl_table=11
                     /translation="HKEDRIGVAKLVGDKGLMKKLGLGTEATRSGIIETIKYRKYIEND
                     GKTKLKPTKKGLLLYKITKYVLVSSPEMTTKWEAYLEQIGQGNKSPDPFIKRVKESIKP
                     TFAELNDNEAGTESVQSVKTQNLEEIGNYQVRTKNKLFEVTPEGASEHFPLWRNIAGHI
                     "
     gene            20586..20714
                     /locus_tag="FE328_RS09495"
     CDS             20586..20714
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024738.4"
                     /locus_tag="FE328_RS09495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_280115769.1"
                     /transl_table=11
                     /translation="MSKSDMRDLLMKGKTSKKKKSKKGNEFKAYWVLKNQRVEFEF"
     gene            complement(21029..21790)
                     /locus_tag="FE328_RS09080"
                     /old_locus_tag="FE328_08980"
     CDS             complement(21029..21790)
                     /NRPS_PKS="Domain: PKS_KR (6-163). E-value: 3e-10. Score:
                     32.2. Matches aSDomain:
                     nrpspksdomains_FE328_RS09080_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006907568.1"
                     /locus_tag="FE328_RS09080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08980"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_208957991.1"
                     /transl_table=11
                     /translation="MTKTYSLITGASSGIGRDLAYKLASEGHNVILVARREQRLKEIAA
                     DIEENYQVSAEYLVQDIGDVASLDDFYEKTKAFNIDLWVNNAGISVSGDFLEMDPNDIL
                     KMLKLNTGALAKLSILYLQDYADEPVQLLNVSSVAGYALMEGAPLYSVSKHFVSTLTEN
                     LAHELANKNKPARAKVLAPAATETEFVGVVRGDAEADVDYSDVFERYHTSEQMAEFAWE
                     LLKSDKVVGIVDLDDFQFKLTDPQFKYAGGN"
     aSDomain        complement(21302..21772)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FE328_RS09080_PKS_KR.1"
                     /evalue="3.00E-10"
                     /label="FE328_RS09080_PKS_KR.1"
                     /locus_tag="FE328_RS09080"
                     /protein_end="163"
                     /protein_start="6"
                     /score="32.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LITGASSGIGRDLAYKLASEGHNVILVARREQRLKEIAADIEENY
                     QVSAEYLVQDIGDVASLDDFYEKTKAFNIDLWVNNAGISVSGDFLEMDPNDILKMLKLN
                     TGALAKLSILYLQDYADEPVQLLNVSSVAGYALMEGAPLYSVSKHFVSTLTEN"
     CDS_motif       complement(21683..21772)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FE328_RS09080_0001"
                     /evalue="1.80E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="FE328_RS09080"
                     /protein_end="36"
                     /protein_start="6"
                     /score="14.2"
                     /tool="antismash"
                     /translation="LITGASSGIGRDLAYKLASEGHNVILVARR"
     gene            complement(21858..23756)
                     /locus_tag="FE328_RS09085"
                     /old_locus_tag="FE328_08985"
     CDS             complement(21858..23756)
                     /GO_function="GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634574.1"
                     /locus_tag="FE328_RS09085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08985"
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_208957992.1"
                     /transl_table=11
                     /translation="MLNYLKTNREGQFLVIGILLIVLGFSLSIMDLTSSRWAFYGAIVF
                     LGFYAAKEALVETFKHKAPNDALLMILSALGATLIQYESEGAVLLLIFAGAEVLEDYVT
                     DKATDSISELMSSVPNQAHIMRENGKVDRVPTDSLAIGDTVIVQKGAQLPIDGTIDRQA
                     VLNESALTGESIPVEKSSGDMVYAGTLNEGDVFYLTVTQTSNDTIFSNIIHMVEQAQQQ
                     PSKKARWIDTFESYYVTGVLIAVPLFIIGLFFLQDLSWQDAFYRGLVLLTVASPCALVA
                     SITPATLSAISNGAKNGILFKGGKVMERFGELKTLYTDKTGTLTQGEFSVTDYELADDY
                     LPTLVYMEQQSNHPIAQAIVAHFQSEHIDLPTESDQIEEIAGAGLKMGNITVGKPDLFK
                     QSTGIETVQAAIDSTDTTVIIAERDRIVGYVNLADKIRVSSREAVQQFQAAGVEVVLLT
                     GDQQRVAEAVAAEIGIPKTYAELLPKDKMNFIQFSQSNNEVVGMIGDGINDAPALAHAD
                     IGIAMGSGSQAAMESADIVIVKNDLQKLFNSYRLSQRLDKIIKQNLFFAIGVIITLITL
                     NILGWLDLPMGVVFHEVSTILVILNGLRLLRNSSTATVEINDTAQSTADESETVTQ"
     regulatory      complement(23873..23971)
                     /bound_moiety="nickel or cobalt"
                     /db_xref="RFAM:RF02683"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02683"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="NiCo riboswitches sense nickel or cobalt ions;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    24046..24061
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     gene            24309..25409
                     /gene="lipA"
                     /locus_tag="FE328_RS09090"
                     /old_locus_tag="FE328_08990"
     CDS             24309..25409
                     /EC_number="2.8.1.8"
                     /GO_function="GO:0016992 - lipoate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lipA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634572.1"
                     /locus_tag="FE328_RS09090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08990"
                     /product="lipoyl synthase"
                     /protein_id="WP_111973909.1"
                     /sec_met_domain="PF04055 (E-value: 1.7e-12, bitscore: 44.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIHIKMPKLLPNMEMGKLVAWVVDEGEIFEAGDPLYEVETDKVV
                     NIIEAEMDGLMMKHRYEEGDDVPVGAIVAEVGPRSSKPDWLRVSYNGSAIKNVSNILEE
                     NRLTTVCEEANCPNIGECFGNNTATFMIMGEKCTRGCKFCNIERTARPGQLDPLEPIRV
                     ADAVRKMKLEHAVVTQVARDDLKDGGAAHMAETVRQIREINPETTIEVLISDLRGSYEA
                     LEDVLAADPDVLNHNMEMPKEWYRKVQPQCNYEQSLNVLRNSKKISPNTLTKTGFMVGL
                     GESDEEISNLMDDILATGCDILTINQYLQPSSEHHKLARYVTPEKFNEYEEMAREKGFK
                     YVVAAPLVRSSYKAAEAFEHAKAKQA"
     gene            25413..26414
                     /locus_tag="FE328_RS09095"
                     /old_locus_tag="FE328_08995"
     CDS             25413..26414
                     /EC_number="6.3.1.20"
                     /GO_function="GO:0017118 - lipoyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00545.1"
                     /locus_tag="FE328_RS09095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08995"
                     /product="lipoate--protein ligase"
                     /protein_id="WP_112787850.1"
                     /transl_table=11
                     /translation="MLLINNDSNDVYFNFALEHYFVTEKQMNEPLLVFWRTEPTLMVGK
                     YQNIYEEVDVNYAKQHDINIVRRPSGGGTIYTDLGSWQFTFIHYQTKREIFFDDFTQPI
                     IEALNRLGVPAEFNGRNDIMIENKKISGNAQYKEKGITVHHGSLLFDTNIEEMVRSTTV
                     DEHKIISKSIKSIRDRVTNIAEYLSNDFTAMDFKQYMVKELMGNEATIYHLTRTDIARI
                     NELADQLFRSWEAKYKRNPTFTRTTTHYLAGGKLSVSLNIKSGRIAELQLTGDFFSGED
                     IEEFCQKLVGTRLDEQAIREKITELTDQSLIYNISNEEIATAILDIPQRNID"
     gene            26430..26774
                     /locus_tag="FE328_RS09100"
                     /old_locus_tag="FE328_09000"
     CDS             26430..26774
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003142512.1"
                     /locus_tag="FE328_RS09100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_09000"
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="WP_004634568.1"
                     /transl_table=11
                     /translation="MMENLNVELLNEAQTHQEVLHQQLTQVIDPELGIDVLNLGLIYKL
                     DLNKKGDCKVTMTLTSMGCPLADEIMNGVRFALLDCDPVEFVNIDLVFSPAWSTSHMSR
                     YARISLGVRA"
     gene            27152..27526
                     /gene="arsD"
                     /locus_tag="FE328_RS09105"
                     /old_locus_tag="FE328_09005"
     CDS             27152..27526
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634566.1"
                     /locus_tag="FE328_RS09105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_09005"
                     /product="arsenite efflux transporter metallochaperone
                     ArsD"
                     /protein_id="WP_112787849.1"
                     /transl_table=11
                     /translation="MKKMVIFDPAMCCSTGVCGPSVDGNLLRVSTVINKLKKKDVVVER
                     HNLANDPKAFVENELINQIIDSEGTEALPITTVDGEVVKKKEYPTNDEFCSFLDIPKAY
                     LDSSKEQSTKKCCCGKGNCC"
ORIGIN
        1 tagctaaagt ggacagtgaa cgccgtagtc ggagtctgca agtgactaaa ggttttagta
       61 tgcatatgat ttttagtgga tcagctggta cgggtaagac atcgatggct aagttattag
      121 gagaagcatt gtatgaaaat ggtgtcttac caacgaatcg gtttgttgtg gcaacccgta
      181 aagatttagt ggcgggatat gttgggcaaa cagcagaaaa aactcatgaa ttgattaaat
      241 cagctaaagg tggtgttttg ttcatcgatg aagcgtatag tttgctgccg aaaaaatcag
      301 gaaatgattt tgcaagtgag gcagtggatc agcttgttat ggactcagaa gagtatcgag
      361 atgatatggt gattattttg gcgggttata cagaagaaat gaaagaattt attgaagaaa
      421 gcaatacggg tctagcgagc cgatttaaaa cctggatcga atttccagat tatgatttga
      481 aggaattatt gaaaatttta ttgatgactc tagagagtca aggagttgtg ttgacagata
      541 aaactcaaac cgaggttctg aaatcattta agagaattta cgaatatgtc gtaggaactg
      601 gaggtaaact tgatgggaac gcacgatatg ttagaaatta tgttcaagac ttgattatgc
      661 agaaagattt aaggttaagc actggtaatt tgagcaatgt taaagatgat gagttaatga
      721 gagtagagtt acacgatatt aaacaagttg aacagaaata tataaaataa acatgctgag
      781 attacaattt aaagagttag ttcattgttt tagtatatta tcatacgcaa ctaactcttt
      841 aaacagcgat atataaatag tgagagaaac aagtgtatgg tataatagcc aaaaggggca
      901 ttggataagg ttctaacatg acaatagata tgcagaagat gtatcattta ctaacattat
      961 gagcgaagta aaagatgtta gtcaaaaaat tgtacaaaaa gaaatcaatt tggctaaaag
     1021 aagacaattt gatattgaat gataataagt cttggcactg gctgaggctt ttttacatgg
     1081 aaaggatatt caataatgaa aacagtggta ttagcagaaa aaccagatca gggacgaaag
     1141 ttagcaaaag cacttggaaa acagaagagt aagactaaag ggtcaattga tgtagcaagt
     1201 tctattctag aaggagatgt cagcgtaact tgggggattg ggcatttagt gacattgagt
     1261 gaaccggatg attatgcaga taaatataag cagtgggaat tagaggactt accaattcta
     1321 ccggatcaaa tgaaatataa ggttagtaaa ggcaaggcgg gtcaatttaa gacggttaaa
     1381 aatttattga agcaggcaga ccgaattatt atcgccacag atcctgatcg tgagggagag
     1441 aatatcgctt attcaatctt taaattatgt gggcgtgagg tttggcaaat accaaagaaa
     1501 agattatgga tcaattcact ccagagcaaa gagattcaac gaggatttaa agaattaaga
     1561 gaagcagagg aaacatatag ttattttaaa gaagctgaaa caagacaagt aagtgattgg
     1621 attattggga tgaattttac tcgcttttta actttaataa tgcaaaagcg agggattgat
     1681 ggtgtctggt cggttggtcg tgttcagacc ccgacaaata ctctgatttg tgagaatttt
     1741 ttagagcgga aaaacttcac tcctgaaccg tactggcaat taaaaggata tcatatctta
     1801 gatgatggac aagtgaagtt tagtgaaccg agaaaagata ataaattttt tgataaaaat
     1861 aaattagagc agtatattca gcaatataaa ctaaataacg ttgaagaagc aacagtggat
     1921 tccgttgaaa aaactaagaa atcaaaatca gctccaaaat tatttagttt aggtggtctg
     1981 caaagctatt gtagtagcca attcggctgg acagcttcaa agacgctaaa agttctacag
     2041 aagttatatg attcaggcta cagtagttac cctcgaacaa gtagccaact aatcaccaca
     2101 aatgaattta attacttatt tgataatatt gatagttata aagattggtt agatattgat
     2161 tttgaagtag cgtactccaa tccccgcaag agatttgttg acaataaaaa agtgaaagaa
     2221 cactatgcaa ttattcctac tgatgaaatc cctagccgtt taagtggcga tcagaagaaa
     2281 ttgtatgaag cgattgttaa acggacgctc ctaatgtttg cggctgatta tgagtatgag
     2341 ttaacggttg tacttgttaa agcaaatgat gtcgtattta aaacaaccgg aactactcca
     2401 attcaattag gttggcgaga tattgaaagt gaggataaag acaataataa tgataattct
     2461 acgttaccag aatatcaaca aagggagata attccattta aagtgagggt tgaagaagat
     2521 gagacaaagc caccaaaaca attgacagag gctaaacttg tcggtgataa gggattaatg
     2581 aaaaaattag gattaggaac tgaagcaact cgatctggaa taattgaaac tctaaaatat
     2641 cggaaatata ttgaaaatga tgggaagaca aaactaaagc cgactaaaaa aggattacta
     2701 ctatataaga taactaaata tgttttggtg ggtagtcctg aaatgactgc aaaatgggaa
     2761 gcttatcttg aacagattgg tcaaggaaat aaatcacctg atccattcat taaacgcgta
     2821 aaagaaagta ttaagccaac gttcgttgaa cttaatgata atgaagcagg tacagaagcg
     2881 gtacagtcag ttaaaacaca aaatttagaa gaaataggca attatcaagt taggactaag
     2941 aataagttgt ttgaggtaac gccagaggga gcaagtgagt attttccttt atggagaaat
     3001 attgcagggg catatatgag taaatcagat atgcgtgact tattgatgaa agggaagact
     3061 agtaagaaaa agaaaatgaa atctaaaaaa ggaaatgagt ttaaagcgta ctgggtgctg
     3121 aaaaatcaga gggtagaatt tgagttttga ttgggattaa gaatgtaaat ttatttttgc
     3181 attctctagg attagagtat ataaaaggtg gattgtaaaa ttaaagtgaa aaaacaattg
     3241 attttttata tatattggta tactattact atagtaaata tttattttgt tatgaaaaga
     3301 gggaatagct tattgggtgt aagatgtaat agagagttga tctaaagtaa aaagtgtggt
     3361 gatgtataaa aaagttatca actatttact gagatgacca atataggtat tggggtaata
     3421 gttgaattat cgtatacaga gtttagatat gctagggtgt tgtaaaatat tatgatgttt
     3481 tacatagcac tggtttacaa gagtacgtga gtactattat atagaaagca ggttattata
     3541 tgaagaaaaa aaagaaatta gtatcagttt ctgcactact gatgttaaca agtgctatta
     3601 tcggtgtgtc tactgtttca gccagcagtg atgagacggg aaatattaat caacccgccc
     3661 tttatactgt gcaagaagga gataatttat atcgaattag tcagcgatat aatataagta
     3721 ttgaggagtt aaaacaactt aacgcattag gagaagcgta tatgctacat cctggtgatc
     3781 aactaaagat taaaagaaat cagagcaatt cagataagaa agtatatgaa gtcaaagcag
     3841 gggattcacc gtataaaata gctcaaaaat ttggtgtaac agtagctgat atttaccaat
     3901 ggaatcacat cgatgctggg actatgctct atccaggaaa tacagtagtg gtatcaggag
     3961 gaactaaaca aacaaccgat actgcagaaa agggaataga ccgcattcat gaagtgacta
     4021 ataataaata taactcagat agttatgaaa ttagagtcga aagaaaacaa gcggatcatg
     4081 cagtcattta tagtttggcc gataaaacac cagaaaagct aacggtcttc aagtggttta
     4141 aatatgatac agcgacagat cgcgtatttg aatcaaccga tgcagcacct aagtcttgga
     4201 tgagattaca tgatggagaa ccggttgctt ctattgagca aacaggacaa gaaaaagcat
     4261 tatcagaaga aggtatccga aaagtgcatg acttaacaga ttatgcttat aatacagaga
     4321 attattttat cactagtgaa gtgattgatg aacacacggt aaaatttgat gtatccgatg
     4381 atagtgctga aaaaataaca ccaatcaaag catttaaata tgatgccaag acaggaaaag
     4441 tttacgtgca agaaattgaa gatcgagcag ctgctaaatg ggaaataata aattaggagt
     4501 gaatatatgg gaaaacaaca aattaaacac agtgcgataa aagtactagc aaccttatta
     4561 ttgtctagtg gatatctatt aattggagac aaaatttatg ctcaagaaat agatgagaat
     4621 attagtcaaa atgaaaataa tgatttagac agaattgaag aaagagaaat aagccaagat
     4681 atagttagag aaactaaaat aaaagaagat tatgacaatg gcgttgatga taacataatt
     4741 gacagtaaag aaagtactca tgaaaaggac acgattattg tacaaagcga aagtgcacat
     4801 tctgaaagta cacattctat ggaagatgat ggattgaata gtgctaattt agatacagct
     4861 aatagtagtc aaaatgagaa agaatttaat ccagtgtcaa ctataactga agaggaaatc
     4921 aatgaaatta tcactgttcg acgtagcaga agtaagcgat cattgaataa tttccagaga
     4981 gaatttttaa ataaaattaa accaggagca attgcgggct ggcataaata taaaatactc
     5041 ccctctatca ccgcagctca aggaatactt gaaagtggat ggggacgatc agatctggca
     5101 actataggaa ataatctctt tggggtaaaa ggatcatacc aaggtaatac tataaatatg
     5161 aatactagag aagaaactcc aactggtaaa gattattata taaatgctgg tttcagatta
     5221 tatcctagtt gggctgctag tattgaagat catggtaaat ttttaaatga aaattcaagg
     5281 tatcgtaagt taataggaga aactgattat agaactgtag ctcatctatt acagcgagca
     5341 ggatacgcta cagcgggaaa ttatgcttct tcactaatag gacttattga atctaataaa
     5401 ttatctttat gggatcagga agcattctct gggagaaaat tatctccaac agtaagttct
     5461 acattatctg ggaatagctc taaacaagta tatacagttg tttcaggtga ttcactttgg
     5521 ggaatagcaa ataaaaatgg tattacatta gatcagttac tacagtggaa taatttgaat
     5581 agaaattcta ttattcaccc gggagataac ttgtttgtat ctagtactaa aaataatgta
     5641 gtttcaagta ccactagcca tacatctaca gcttcttcaa ataaacaacc aacagctaaa
     5701 ggtaaaacat atacagttgt ttcaggtgat tcgctttggg gaatagcgaa caaaaatggt
     5761 attacattag atcagttact acagtggaat aatttgaata gaaattctat tattcacccg
     5821 ggagataact tgtttgtatc tagtactaaa aataatgtag tttcaagtgc tacaagtcat
     5881 acacctacac cttcttcaaa taaacaacca acaactaaag gtaaaacata tatagttgtt
     5941 tcaggtgatt cactttgggg aatagcgaac aaaaatggta ttacattaga tcagctacta
     6001 cagtggaata atttgaatag aaattctatt attcacccgg gagacaactt gtttgtatct
     6061 agtactaaaa ataatgtagt ttcaagtgct acaagtcata cacctacacc ttcttcaaat
     6121 aaacaaccaa caactaaagg taaaacatat acagttgttt caggtgattc actttgggga
     6181 atagcgaaca aaaatggtat tacattagat cagctactac agtggaataa tctaaataaa
     6241 aactccatta ttcatccagg agatacgtta ttaattaata aataatatat attattttaa
     6301 agtggtaact aagtacgtaa ttgagtaggc tttttccggt aattgaccga ttatagccta
     6361 ctcaattttg ctattaatca ggtcattatt gtcgtaatta atagacgtta gagcccaagc
     6421 atttaattat ttttttcgtc agcgcccatg atttaggcga ctagttccac ctcaaaaaat
     6481 cctctaaaat agttaatgta aagtaaaaac tattgagagg attttttgta tgtcaaaacc
     6541 agaaattatc gtacccactt gaagccattg cttgataaat tcaccgaatg gttagaccat
     6601 catcagtatc taacaaaggc taaactgggc aaggccatta tctatgctcg taagatgctt
     6661 ccgagtgtgt acttattact cgatcatgcg ggtttgagca ttagtaacaa ttccgctgag
     6721 caagctatga gaatacccgc tttgggacgt aaaaattggt tgttttctca gagcatcaaa
     6781 ggagcgatag caaatgggta tttcttaacg gtcatccaaa cagctatagc aaatggtctg
     6841 gattgatgtg accccaaaag ttgaagtttt aaatagtggt gattaagcat gtgattgagt
     6901 ggcttgtttc cggtaattaa ccggggataa gccgctcaat tttactttta ttcgatcgtt
     6961 attgtagaaa tgaatgtagt tttcgattct gcacttgagg tcattaaaag gcactttgtc
     7021 ttgaccataa tacatttctt gctttaagag cccaaagaaa ttctccatcg gtgaattatc
     7081 aaggcagttt cctttccgag acatgctttg ataaataccg tgctccttta aacaattgat
     7141 ccatgcatga tgttgataat gccacccctg atcactgtgg atcgttgtac gataaggggc
     7201 atggcgttca atacgagaaa tcgcttctgt tagtggctct agggcaatat ctaatgttgg
     7261 acgtttcgcg atcttaaagg caataatttc gctattatat aaatccatta tcggacttag
     7321 gtatagtttt tcatccttga gacacttaaa ttctgtgaca tcagtgacca gtttttgtag
     7381 tggaacggat gtcatgaatc gtcgattcac ccgattgctg gctaccttcc ctactttccc
     7441 tttataggaa ttataacgac gacttttacg gaaaaatttt atacatttga tccccagctt
     7501 ctgcataaga cgttggactc gtttatgatt tacacagtac cccatgtttc ttaaggtgag
     7561 tgttattcgt cgatagccgt atgtctcgtt tgaatcgtta aaaatttttt gaataagctg
     7621 ttcaagcgga tgatcttttg ggtcatttgc tttttggccc atataatagt gatatgttga
     7681 tgccggtaaa tcaataacca ttaagacatc ttttaagcga aagtggtctt cagttagctc
     7741 aaaggctatc cttgattgtt gtcttcgcga gggtcgctca atccccgctc tctcaacttt
     7801 tttaaatagg ctaactcaat ctttaataaa ttattttctt ctcgtaattg tgcattctca
     7861 cgagctattt gatctgtttt ttgctttgac tgtgttgttt tctggttaga cgagcgtgat
     7921 gatttaggca ttttgggtgg cctccctatc ggcttattta gactttgtac acctccttcc
     7981 ataaatagcc gtttccaatt cgctataata gagggttcgc ctatgccaaa ggcgttagcc
     8041 gtctctttat aggaagcgcc agtctctagc ttaaagttta atacattgag cttgaaacgt
     8101 aaagtatatt tcttctttgt cttctttcgt tttagtccag cttccccata aagttgatac
     8161 tgattaaccc agttttgaat gagttgttca ctggatacat catatttttt agcaagcaga
     8221 cgatagccta atggaccatc gagatatgct tgaacaatat ttaatttaaa ctggtatgaa
     8281 tatgttttgg acataaatga acccccgaaa attagaataa ttgactctaa cttttggggg
     8341 tcagtacaag aatgtcacta aatctaaata ttaaatctca tatgaatttt tgtagtttaa
     8401 taaattttga ttttcttcga agttttggac atcactagat ttatgattac tattttctct
     8461 aaagaaatag gatgtaggaa cttgtaatct attgcttaac tgctgtataa ttttgctgct
     8521 gggtttgatt ttgccttgtt caatcttact aattaatgct tgggtacaca atccttcagc
     8581 tagttctctt tgacttaaat ttagatattc tcttctatct ttaatttttt gtccaatcaa
     8641 aattatcaca gtccttttca aatataaatt tataataagt aagtatacaa catgttagaa
     8701 taatcgaagt atttataaat taaagtatat aataccaagg ctatgcgctt ttacaattgc
     8761 ttgaattgta gattgagtat ccaatttttt attaattgaa tataaatggt ttctgattgt
     8821 gcgtgtcgta atccctagat caaaagcaat agatttttgt gtttctccat ttgctaattt
     8881 ttctaaaatt aatttttctt gagaagttaa aacatgtcta cagtcattaa ttatatacga
     8941 gggagaactt tgattatgta ttttctttaa ttgagtgatt aatgtatcga tatcgatagt
     9001 ttcattgaaa aatgcaaatg caccaatatc ataagctatt tgtttaaact ctaataaatc
     9061 aagagcagac ataaaacata gtttagaacg tgtttcatct atgatttttt tggcaagttt
     9121 aaattcattt agagtttcta aatgaatcac taataaaata atatcaatat ctaggagaat
     9181 tattttgtta attaaatcgt gagaaggttc atgaaaataa aacgtatcta tagtattagc
     9241 ttgtgttaag gctgtaaaaa tacacttccc agagaaacaa tgttggtcaa ttatgagaac
     9301 tttcatacat aagatcctcc acactctata ttttatgaat atattataac atattgtgaa
     9361 tttgttatca acatttccta ttttacttat tgttattcgt gtaataaagt tttaaaataa
     9421 caattaggag ctcctagaat attaaatatg aggaggaaaa aaatgaaaca atcagataaa
     9481 gatacagtgc aagggaataa agagcattta gtagaaaaga attttaagat ttatgatgaa
     9541 gttacagacg aagatttaca agaaaatggt ggagtagctt ggacatcact tgttccaatt
     9601 tctttagcaa tatgtccatc aacaaaatgt gcgtctatta caagaccatg taataaatag
     9661 gaggtagaat catgaataaa gattttgata aagaattgtt aaatatttca gggaacttga
     9721 aagaggagtt atctgaagca gacttagagc agatttctgg agctggtgtc ggtaaatgga
     9781 ttcgcaaatt gagtaaaggt aacactggga aagtctgtac tttaacttgg gaatgtggta
     9841 tttgtccttc ccatacgtgt ttcttatagg ttaatgattt tgaaatagaa atataaatta
     9901 agttgttctg cctcttaaat gtaaatattt ttctaatgag aaaaagaggc aggacaactt
     9961 aaacaacatt taaactttaa tttaaggagg agtcaaaaga atgaaaagca gttttttgga
    10021 agtaaaagaa agtacaaaaa agctattatt tcaagatctc aaagggagca atattgacga
    10081 aatataccaa gattttgata taaactctat caatcaaact agagaaagta tattgttcat
    10141 ctttaatgag gagcagaaaa agaaaaatga aaagcaattt gaatacacgg catataaaaa
    10201 tttagggaat tttagtactt atttttgtca atattttttg actcaatttg atttgtattc
    10261 aaatgaatat atagaagaaa tagaagacat tgaatttttc aaaaaaaatc ttacagatca
    10321 attaagtaat aaaattttaa aaatatcata tcggacactt atttacgaga tgaatgtaat
    10381 gcgaaaagag aatatgtttg aatcaacttt aaaagatgaa caatatcttg aattctgcaa
    10441 taagttaaaa gatagtacgt ttgttaagga gatattatta aaatatcctg tgatggatta
    10501 cttagtgtat acaactatta ccttttttaa agaatttatt tttgaaatag taaaacactt
    10561 taaaaatgat aaatctattt tagttcagaa cacactaatt attgaagaag ataagataaa
    10621 gtgtatgatt ttgggacaag gagactcaca taataaaggg aaaacagttg taaaaataaa
    10681 aatgagtact ggaaagacac tctattataa accaagaaat ttagaagtag atctattatt
    10741 taataaagtt attcaattac tttctgagaa ggaaaatata gatttatgta cgtatggcgt
    10801 gtgtagcttg gaaaatcatg gatgggtgga agaagtagag tataaaccag tcaaaacact
    10861 ggatgaatta ttcatgtttt ataaaaatat gggctcttta ctagctatac tatatgcact
    10921 gaatgctgta gatatacata ttgataatat cattgcaaat ggagaaattc ctatgttgat
    10981 tgattgtgaa agtttatttc atagttcaga atatcatgaa gaagaagata atgctacaag
    11041 atatttaaat aactatttat cacaatcagt attatctatt ggagtgctcc catttatttt
    11101 tggaactgga tcaacagata tcagtgcctt atcggatcaa aaaaataaaa aaacttcaat
    11161 taaagttcca acaataaaga atagtaacag atcgaatatg aaattagtaa gagagtacgt
    11221 tactatggaa gaaagtaaaa ataatcctaa tgcaaatgat ttaaaaatta gtgaggaaga
    11281 aaaagagaaa aatattttag aaggatttga acttggttac catgcagtac taagctgtag
    11341 aaaacagata ctgcacttaa ttgacagaag taacgataag atgatattac gtcacattat
    11401 caagcccact ttattttatt caaatttaat tgaaataagc aatcaccctt caatattaat
    11461 agattttgag cttttagaat tattatttgc tagaattcaa gatgaagaac attctaaaaa
    11521 aataaatcaa gaagaattta aagatttact tcaaagagat gtgccgtact ttttctcttg
    11581 ttttaaagat aaagatttat ataaaaatgg agaagtgata gaaaaaaata gttttactga
    11641 aagtaaatac tcaattttta taagaaagat gaacatgtta tctatagaag ataaagaaag
    11701 acagatggac ttaattaagt cgcgattatc tattagtaga tttaatcaag atcagtataa
    11761 tctaaaatca tttaaagaaa ataacgctat tgatttaaat actaaaaaac aatttattat
    11821 agatagagca attaaaatag gaaatgaagt tataaatagt gctgtgaaat ataacaacac
    11881 atatagttgg ctatcttatc aattaattgg cgaagtgggc gccccttctt ttttatccat
    11941 taatgaaatg gattataatt tatatgatgg tttagcagga caaggaatta tgttgcttgc
    12001 tttattttta cagactaatg ataacaaata caaaaaaatg ttaaatgcca ttatagatga
    12061 tatcttgaac aatgtacaaa ctctaaaagg ctgtccttta ggagcttttt caggaggata
    12121 tggaatcata tatttattag ctttgtattg taagaaagtg gaggagagag acacatatat
    12181 agataaactt ttgtttttaa ttgaaagtag tttagatgaa ttaaaaacag tagaagagta
    12241 tgacattata agcggttttg cgggtatatt attaatacta acaaatttgt attgcaataa
    12301 tataaaatcg acttctgtag ttaaagcaat ggatatctgt gtaaaatatt tgattgatgg
    12361 agtaacaacc gataaaaata aatatatcgg atggaaacaa agcgaaggag gagaaatact
    12421 tactggattt tcacatggaa tagcgggaat tacgtatagt ttacaaaagt atcaagaatt
    12481 aagtatgaat tcaattaatc aatcagaagt gattaataaa attataaaag aaactagaga
    12541 gtttcaagca aagtctaaaa acaatggtaa atttattgat ttacgtaagg agtcatataa
    12601 taacattccc tatgcgtggt gccatggttt gccaggaatt atctgttctg gtgaacaaga
    12661 ctaccaaaca aaacaaaact tgatagatat gacagaaaat gcctttggaa gaaatcattg
    12721 tttgtgtcat ggggatttag gaaatctaat tatattaagt gaattcaata aagatcaaaa
    12781 ttggatagta gattatgcat atcatatttg tactacagaa acattatttt ctggaattgg
    12841 aatttcagac ctctctagcg atgaatttat ggtaggaaat tcgggaatat gttggggatt
    12901 gatatactta tttaataata acctaccaaa cgtattgaaa ttagaaattt aacgtaaggg
    12961 aaatgaaata tggatactcc aatcatttta caaaaaaata agtatgagtg tggcttggca
    13021 gctcttgcaa tgttgtttag ttacaaggat aaaaaaatag atatatcatt tttgaaaaaa
    13081 gataagcaag aaataattgg aagagacgga ttaagtttag ctgacttaaa aaaaattgcc
    13141 aaaaccaatg caggaaacct aagagtattt aaagtatatg atatcacaaa atatttagac
    13201 acttatgaaa ttactcaacc gttgttgtgt tatataaata atagtcatta tatagtggtt
    13261 acatgtaaga aaaaagatag aatatgggta aatgatcctc aagtaggcag atataatatt
    13321 tcagaacaag aattttcaaa tctattttca ggctatatag ccattttaga aaaaaataaa
    13381 aaaaataaag atatatttga atttagctcg aaaaagaatg ctagattatt cagttatata
    13441 actactcatt catctgtggt aatacagctt atcttttgga cgttggtttt tcaggtatta
    13501 aatatcttat ttccggcaat gatacagaaa attattgatc aagaaataaa tataacaatt
    13561 tttagtttat ttatgatact aggattatcg atagtctatt atcttatatc aaaatatcaa
    13621 ttgaaattgg caacaaaatt acaaattatt atcaataagt tattgacgat agattttgta
    13681 aaaaaagtat tctcgataaa aagttcattt attgaaataa attcaattgg gtattttact
    13741 aatagtcttt ctaatataaa tactataaaa gaaattttgg ttagtttgtc tacacttatt
    13801 gtaattaacg ttactttaat gttgatttac acaatagcat taatttactt ttcgccaata
    13861 ttaacactga tagtatacgg atttgtaatt atgcaaggaa ttgttttatg gaaagctgct
    13921 cccaaaataa gagattttat aggaggggaa ataaaaaata atattgattt ccagaattac
    13981 tatatagaat cgttaaaaaa ttataacaac ataaaatcaa tgggagaccc aaagtatgta
    14041 gttaacttta ttcttgataa gtttactggt caattgcatt cttttgaaaa aagaatggat
    14101 attcaaatta aattaacttc atttttaggc acggtgcaat ggttattacc atttatagtg
    14161 ttaatagctg gctatttact tatggattct attaacttaa caatggggtc tttagtagct
    14221 ataagtgcca tagcattaag aatagttaca ccgttagcat cagcttctga agtctatcaa
    14281 tcaattttaa tgatgaaaga aatttttgaa aatatcgata atgtgttaac tcaacctgaa
    14341 gaaaatgctg ataaaggcaa cagtattgat actatgcctt ttccaattaa atttaatgat
    14401 attggttttt cttatgggaa tactgagata ttcaaaaata taacattaaa tattgaaaga
    14461 aatgataaaa ttattataaa agggaaatct ggagaaggga aaactacgct actaaaatta
    14521 ctaactactt tatatgctcc tacagtaggg aagatttatt ttgggggtaa agaattaaag
    14581 aactataaat taaatcacat aagaagtaaa attggatata tgagtcaaga ttattctctg
    14641 atatctggaa ctataatgga caatataact atgtttgatg acagaattag tttaaaagat
    14701 gtggaaaaag cagcccagtt agtttgtata gatgaattta taaatcaaat gccaatgaat
    14761 tactacactt ttttgaattc gaatggttct tcgctgtcag gaggacaaat ccaaagaatt
    14821 tgtcttgcta gagcaattgt taggaatcct gaattattag ttattgatga aggtacaagt
    14881 aatttagata aggacttaga aagaaaagtt atacgcaacc tttttaattt gaactgttgc
    14941 atttgtattg taagtcatcg gcataacgag attgatggaa tcaataaaga aattgttatt
    15001 aataataatt ctttactaat taaaaaatat aataaagggg atataaattg aacacaacta
    15061 ataaactaac aagtcttttt ataaaggaaa attatttaaa tagtattgat gacaatattc
    15121 aagttattat agaaggagag cagacatttt taaataagga caagatttca aaaacattgt
    15181 atgaatactt ctataataca atatatgaag tgtctatcaa acagttatta aaatggttcc
    15241 attcctcttt tgattatata gatgaaacag ataaacaata taatataaat aaatttataa
    15301 gttttaaacc attttattct acaagagaat ttctaatatt agataaattg atagtgaaaa
    15361 ttatagaaaa taaaacaaat tttgcaaagg aagtgataag taattttcag aagagttatg
    15421 agaatataaa atctaaatat agacttgggg aatctataaa tttatgtata gaagatttaa
    15481 tatttgaagt aggagattta cacaatagta ataaaagtag ctgtgttatc ataactaatc
    15541 agaaattaaa actagtctat aaaccaagaa cagcagccaa tgataaattc ttttatgaaa
    15601 tagtaaattt tcttgaaaac catctaaatt tggttcaaac agaatatcca tcactaataa
    15661 tctcggaagc tacattttct atttttcctt ttattgataa acaagaatta actgataatg
    15721 ctgaagctga ggaatactat tatcgactag gcatttcaac tatggttctt tatgtagttg
    15781 gagcaacaga tatccatttt gagaatatta tgtcgaataa gcaatttcct atattcattg
    15841 atttagaaac attatttgat gttactaaaa taaaaataca ggaagagagt aatgaattta
    15901 acagcgaact actccagtct gtgttgacaa gtcatatatt tgattattca ttaaatccta
    15961 atcaaaccga tatagtaggg attgggggct atacgacatc tgttaatttg gaatcagaag
    16021 aaaagcttat taataaagat acagatgaaa tgcatttatc ttttatacag actaaaaaag
    16081 atatatttaa tgtacctagg ctagctaatt gttttcttga gataacagaa aagaagacac
    16141 aatttataaa agggttctac gatgcttaca atattatttt aagacataaa aactatttga
    16201 aaaaaataat aaaagactat agttcatcta taattttacg tacgttgatc agaccaacat
    16261 atatttacca taattatcga agaaaaatat tagaagatct tactattatc cacaaaaatg
    16321 aaagattatg gaaaaaatta gagcaaaatt ctatggtaaa taaagaaatt ataaatctag
    16381 aaaaaagagc attaacaaga tatgatattc cattttttta ttgtataatg aatgggtgtt
    16441 cactttgttc agagggcgct cgagttgaag gatttttacc tattactcct ttagaatact
    16501 atttgaataa actagaaaaa ataaccactg aagattgttt agttcaatta tggtatttaa
    16561 atcaaagtat tgaaatatat aacaactatt tatttaaaaa aataaatact gaaaataaga
    16621 atgatataaa aatgtatttg gaaagaagaa taggtgcaca cctagctgaa gatgtttcgt
    16681 tttgctcaat aaagatgtgt tataatagtg acatcgtttt atctccgatg aattatgatc
    16741 tatatgatgg tttgtatggc ttgaaattta tggacaaaat tttttcagag agatacaatg
    16801 tacatttaat tagagatagg aacaaaattc aaaatattat tgataagtta tctaaaatta
    16861 atctagccaa tttttctgca tattcaggcc aattttcaca attaaaatat aatttattaa
    16921 aatttgaaat ttctaactca aatattgatt ttaagaatga ttggataaca tacagtcaat
    16981 tagtagagaa aataaataaa ctaagtaccc ccaatattga ttttttaaat ggtatttcgg
    17041 gaataatctc acttatgata gaactttatc ataagactaa agatgaaaga atcattattg
    17101 atatagaaag aacttcaaac ttcttgtggg aggagtatca agagtctcca atccaaaact
    17161 caattattag ttttgctcat ggtgcaattg gaatagagta tgttttttct aaagtggttc
    17221 ctttattgtc tgatgattca aaaattaaac agaaattaat tagacatctg gatgaaaagt
    17281 tgactgaaat aagaaattat attcagcatg ttattataaa tgaaactgaa ataaattaca
    17341 catggtgtaa tggattaaca ggtttcctgg ttgcgtggct cgctataaac aaacacttaa
    17401 attgtcaatt tagtgaatta gagaaaaagt taattaataa atatatagat aattatactt
    17461 ttaagatgtt agatgattct atttgtcatg gacatgcagg aaacttattg tctttaaatt
    17521 atattttaga tagaaattta aataaaggct ataggagagg agatcttatt gatttaaaaa
    17581 ttcagataga acgttgttta cagaataaga taatgtataa taaaatttgt tctggttatg
    17641 aatataaaga tataaaaagt ttcagtttat ttttgggaga tttaggagta tatgcgagtt
    17701 atatcttgag tactgaagga atctcctcgt caatacttta ctaactgcaa ggaggataaa
    17761 agatgttaag tatgcaatca atttcgaaaa aatatggaga gctatatgcg ctaaaagatg
    17821 cggaattaga gataaagaaa ggtgagatgg tcgcattaat tggaaataat ggatccggaa
    17881 aaacgacatt gatgaaaatt attagtggta ttaccaaagc gagtaccgga acgtttgagt
    17941 gggagaccaa tcgtcaaact aatttgattg aaacaccgga gttctttgat tatctatctg
    18001 gatataagaa tttagaatat tttcgcattc aaagagggat tcaagatcaa catattatcg
    18061 aagatatact ggaaagagtc ggtttaccga atgaccgtaa aaaatttaaa cagtattcat
    18121 tagggatgaa gcaacgatta gctatagggt tatgtttgtt agggaatcct gaatttatgg
    18181 ttttggatga gcccacaaat ggagtggatg ctcaggggat tatcgatatt cgaaatttac
    18241 tcttaacttt aaataaagaa gagcaattga cgatgttgat tagtagccat aatataaatg
    18301 aactttacaa tatcgccact cgatttgtat ttatcaaaag tggagagatc aaaaaagata
    18361 tcagtaaatc agaattaaat gaaaatatcg gaacatttta ccaagtgaat atcggccgga
    18421 tacaagatat agaagcgcta ataaatgaca cggtattaca gtcgaattat tatacaatcg
    18481 acgacaagaa tacgctaaaa ttggttaaaa attttgaaac aagtcaattt attgaacaat
    18541 tgtctcaaaa agagctcatt gacgatatat ctgaagtgca agtgacacta gaagactatt
    18601 atctagaaat aatgaaaggg tagaaagctt atggtgaaaa aatatatcta ttcagaacta
    18661 taccgaatca aacatattcg aatgtacatc gcattgtttt tcataacaat tttatttccg
    18721 atagctacaa cagcttttct ttcgataatt tctctccagc agacagagcc tactacgaaa
    18781 gaatttgggt tgtattcatt gtatatgtta atatttattg gtctttactt agcctatccg
    18841 attgttattt gtgcgaacac agtgaaacct aaatacgttg aacgacaaat tttgtcatca
    18901 gggattacaa aaaacattct atatttttct gatttatttt atattaacat tatccaacta
    18961 attatgttag tattgtattc ggtgtctagt atcatatcga ctactttgtt gttagaaagc
    19021 gctccagggg cagaagactc actggatcta gttaccgtga aagagtttat aataataatg
    19081 tgttgtatct atataaccat gattttatcc agtattgtat tatatagttt gcagctggtg
    19141 ttgagcaata aaatttttgc gacaggatta tttatgtttt tagtctacgt gattccgttg
    19201 gttattgcac aaatcagata tttctcggat atagcggatt cagtcgctca aataattccg
    19261 tttttacaag ttgccttttt ctataaaggg gatagtccat taagtatgtt attgcttatt
    19321 catggtattt ggatagcagt gaccattatg atatgtaaca cgatttataa caaaatagaa
    19381 gcttaaaaat aataagaagg agttgttgaa aaatgaaaga atcattattt tttgtgtcac
    19441 tattgttttt agcagtgttt ttaatcttag gagtttattg gctaacccag cgatgggtat
    19501 acgatgttga tgttagggga ttgcgtaaat ggattttaac gtcctttgta ttgtacgcta
    19561 ttacttatgg aattagcttg tatttaatta attaaaaaat aattctacaa ttttgggtgt
    19621 tggtgaggat ttttctcgcc agcaccttat acaattttac ctgtagaggt gattagtgga
    19681 gatgagactt caattttaat gatatactct gttgctgtaa catttgtgct aaaaaaatgg
    19741 tagatcttca gtggtccata ggtttacgtc gatatcaatc tgctaattaa ttttatatgt
    19801 tatcattttc aaatatatga tatgctattt ttataagtgt ttaatgctag aagtccaata
    19861 agatttttac atttttatat caatgtggta caaagaagca tacgggttat acactcatat
    19921 acttacacta cgagaggaat agatgccagc gttctcagga acggtggcct atttggtgat
    19981 gaaagtccac tatgagcctt tacagtagga attattagcc aaaggcaagg gtgtctatcg
    20041 tgagatggaa tctgaaggaa gccagaggca gacacctgca ctgacgaaca gaaatctcat
    20101 aaagaagacc ggataggtgt ggctaaactt gtcggtgata agggattaat gaaaaaatta
    20161 ggattaggaa ctgaagcaac tcgatctgga ataattgaaa ctataaaata tcggaaatat
    20221 attgaaaatg atgggaagac aaaactaaag ccgactaaaa aaggattact actatataag
    20281 ataactaaat atgttttagt gagtagtcct gaaatgacta caaaatggga agcttatctt
    20341 gaacagattg gtcaaggaaa taaatcacct gatccattca ttaaacgcgt aaaagaaagc
    20401 attaagccaa cgttcgctga gcttaatgat aatgaagcag gtacagaatc ggtacagtca
    20461 gttaaaacac aaaatttaga agaaataggc aattatcaag ttaggactaa gaataagttg
    20521 tttgaggtaa cgccagaggg agcaagtgag cattttcctt tatggagaaa tattgcaggg
    20581 catatatgag taaatcagat atgcgtgact tattgatgaa agggaagact agtaagaaaa
    20641 agaaatctaa aaaaggaaat gagtttaaag cgtactgggt gctgaaaaat cagagggtag
    20701 aatttgagtt ttgattgata actttataca aaaaggaaaa atgtcccgaa tattatactg
    20761 aaatccgaga caagtaattt tgcattcatt ttgtattgag gacaattgaa atgggctata
    20821 gacactgttg tgacaaggat tgtaagaagg gagtttaaat cttcttatgc gcattacata
    20881 ttaagttgca atatctcatt gcacatcgaa ccccggaaga gtgatcaact tttttcgagg
    20941 tttttttgat tacttattaa aaaatagccg agaaacgcta gtaagataga tgtttctcgg
    21001 ctattggtgt ttcaattagt taaaccgctt agttaccgcc agcatatttg aactgagggt
    21061 ctgttaattt gaactggaaa tcatctaagt caacgattcc gaccacttta tcggacttga
    21121 gcaactccca ggcaaattct gccatctgtt cactggtgtg gtagcgttcg aagacatcag
    21181 agtaatcaac atctgcttca gcatcaccac gaacaacgcc gacaaattcg gtctcagttg
    21241 cagcaggagc aagtacttta gcccgagctg gtttgttttt atttgctaat tcgtgggcta
    21301 agttttcagt taaggtactg acaaagtgct tagacacgga gtagagtggg gcaccttcca
    21361 ttaaagcata gccggccaca gatgagacat tgagaagttg gacgggttca tccgcataat
    21421 cttgcaagta aagaattgac aacttagcta gagcccccgt attgagtttt aacattttta
    21481 agatgtcatt gggatccatt tccaagaagt caccggatac actgattccg gcattgttaa
    21541 cccagagatc aatgttgaat gcttttgttt tttcgtagaa gtcatctaag ctggccacat
    21601 caccaatatc ctgcacgagg tactcggcac ttacttgata gttttcttcg atatcggcag
    21661 caatttcttt tagtcgttgt tcacggcggg ccacgaggat aacattgtgt ccttcactag
    21721 ctagtttgta tgcgagatca cgcccgatac cagagcttgc tccagtaatt aaactatatg
    21781 tttttgtcat gagttatcaa cctttctatt tgttacttag tataccatag ataataatgt
    21841 taggagggaa cggtgcttta ttgcgtgacg gtttcagatt catcagcggt agattgtgct
    21901 gtatcattaa tttcaacagt tgctgtagag ctgtttcgca agaggcgcag gccatttaag
    21961 ataacgagaa tagtcgatac ttcatgaaaa acaacgccca tcggtaaatc gagccagcct
    22021 aaaatattca gtgtgatgag tgtgataatc acaccaatcg caaagaaaag gttttgctta
    22081 ataatcttat ctaggcgttg acttaagcga taactattga acaatttttg tagatcattc
    22141 ttaacaatca caatatcagc agattccatg gccgcttgcg aaccgctacc catcgcgatt
    22201 ccaatatcgg catgagctaa ggctggcgca tcgttaatgc cgtcaccgat catgcccacc
    22261 acttcattgt tggactgact gaattggatg aaattcattt tatctttcgg aagcaattca
    22321 gcataggttt taggaatacc aatctcagct gcaactgctt cggctacgcg ttgttggtca
    22381 ccagtgagta agactacttc aacgccagct gcttggaact gttgaacagc ctctcgagaa
    22441 ctaactcgaa ttttatcggc taaattaaca taaccgacga tgcgatcacg ttcagctata
    22501 ataacggtcg tatctgtact gtcgatagct gcttggacgg tttcaattcc tgttgattgt
    22561 ttgaataaat caggttttcc gactgtgatg ttgcccattt tcaagccggc tcccgcaatt
    22621 tcttcgattt gatccgattc agttggtaag tcgatgtgtt ctgattggaa gtgagcaaca
    22681 attgcttgag caattgggtg attagattgt tgttccatat agaccagtgt tggaagatag
    22741 tcatcggcta actcataatc agtgacactg aattctcctt gagtgagtgt accagttttg
    22801 tcggtataga gtgtcttcaa ttcaccgaag cgttccataa ccttaccccc tttgaagagg
    22861 ataccgttct ttgcgccgtt actaatagcg ctgagtgtgg caggagtgat agaagcaact
    22921 aaggcacaag gactggcgac tgttaagaga acaagtccac gatagaaggc gtcttgccaa
    22981 ctgagatctt gcagaaaaaa taatccaata ataaatagag gaactgcaat cagaacacct
    23041 gtgacataat aggattcaaa tgtatcaatc cagcgagctt ttttggaggg ttgctgttgt
    23101 gcttgctcga ccatatgaat aatgttggag aagatagtgt cattacttgt ctgagtaact
    23161 gttagataaa agacatctcc ttcattcaat gttccggcat agaccatatc accgctagat
    23221 ttttctactg gaatagattc accagtgagg gcggattcgt tcaatacagc ttggcgatca
    23281 atcgtaccat cgatcggaag ttgagctcct ttttgaacga tcactgtgtc accgattgct
    23341 aaggaatcag tgggaacacg atcaaccttg ccgttctcgc gcataatatg agcttgatta
    23401 ggaacgctag acatcaactc agagatgctg tcagttgcct tatctgttac gtaatcttct
    23461 aacacttctg caccagcaaa aataagaagt aatacagcgc cttctgattc gtattggatt
    23521 agggtggctc ctaaggctga gagaatcatc agcagagcat cattgggggc tttatgttta
    23581 aaagtttcaa ctagcgcttc ttttgctgca tagaagccta aaaatacaat agcaccatag
    23641 aatgcccacc gactactcgt taaatccatt attgataggc tgaatcctag tactattaat
    23701 agaataccta tgactaaaaa ttgtccttca cgatttgttt ttaaataatt taacattgta
    23761 atctctcctt tggtaaaaaa taacttgaat aatgagtaaa taaactgcgc tagtgaaacg
    23821 accctccttt tttagctact gtactaaaaa aggcacacct gtggacagaa ttaactgtct
    23881 cacagatgtg ccttaacact ctgctgctac gtttagtagc cgggctgcat gaaatagtca
    23941 cctattcacc gcttgctcag atttgtgctt cttttcagta gaagcgctat gtaattttta
    24001 ataactcatc taacttattt atagtatact acatggtaat aagattgtaa agtatttcac
    24061 gaatattttt caattttttt gatagtaaat agtaacgagt gatggagaga ataacgggtt
    24121 ctcactgtat ttaaagacga aattgttttt ataatatgcc ttattatact tttttatatg
    24181 gaattttatt aaatgttagg tttattgata attttttgtc tttttttatt gtaatggtta
    24241 ttattttttg gtagattata ggcaagaaat cggtataaaa actattctac attggagtga
    24301 ttataattat gactattcat atcaagatgc caaaattact tcccaacatg gaaatgggaa
    24361 aacttgttgc ttgggttgtc gatgaaggtg aaatattcga agctggcgat ccgttatacg
    24421 aagttgaaac agataaagtc gttaatatta ttgaggcaga gatggatggc ttgatgatga
    24481 agcatcgtta tgaagaagga gatgatgtac ccgttggagc aattgtcgct gaggtgggac
    24541 cacgatcgtc aaagcctgat tggttgcgcg tgtcttacaa tgggagtgcg attaaaaacg
    24601 tctctaatat tttagaagag aacagattaa caacagtttg tgaggaagca aattgtccga
    24661 atatcgggga atgtttcggc aataacaccg caacctttat gattatggga gaaaaatgta
    24721 cccgtggctg taagttttgt aatattgaac ggaccgctcg cccgggccag cttgatccac
    24781 ttgagcccat tcgagtggcc gatgcagtcc gtaagatgaa gcttgagcat gctgtggtta
    24841 cgcaagtcgc acgagatgat cttaaagatg gtggtgcagc gcatatggct gagactgttc
    24901 gacaaatccg cgagatcaat ccggagacaa caatcgaagt cttgatctca gacttgcgcg
    24961 gctcttatga agcattggaa gacgttcttg cagccgatcc cgatgtcttg aaccacaaca
    25021 tggagatgcc aaaagaatgg taccgaaaag tccagccaca atgtaattat gaacagtcct
    25081 tgaatgtttt acgcaatagt aagaagattt caccgaatac cttaacgaag actggattca
    25141 tggtcggtct aggtgagtct gatgaagaga tttctaactt gatggatgac atcttagcga
    25201 ccggttgtga tattttgacg attaaccaat acttgcaacc atctagtgag caccataagt
    25261 tggcccgcta cgtgacaccg gagaaattca atgaatatga agagatggcc cgcgaaaaag
    25321 gattcaaata tgtcgtagca gcaccgctcg ttcgctcatc atacaaagca gcggaggcct
    25381 tcgaacatgc taaagcaaag caggcttagc ctatgttgct tattaataat gattctaatg
    25441 acgtatattt taattttgct ttagagcatt attttgtaac ggaaaaacaa atgaatgagc
    25501 ccttattagt tttttggcgg acagagccaa cgttgatggt tgggaagtat caaaatattt
    25561 atgaagaagt ggatgtcaac tatgcaaaac agcacgatat taacattgtg cggcgtccat
    25621 ctggtggggg gactatttat acagatttag gtagttggca attcaccttt atccattatc
    25681 agacgaagcg agagatattc tttgatgatt tcacgcaacc gattattgaa gcactcaatc
    25741 gattaggtgt tccggctgaa tttaatggcc gaaatgacat tatgattgag aacaaaaaaa
    25801 tatcgggcaa tgcacagtac aaagaaaaag ggattacggt ccatcatggc tcattgctct
    25861 tcgatacaaa cattgaggaa atggtgcgca gtacgacggt ggatgaacac aaaatcatct
    25921 caaaaagcat caaatctatt cgcgatcggg tgaccaatat tgctgagtat ttgtctaatg
    25981 actttacagc aatggacttc aagcagtata tggtcaaaga attgatgggt aacgaagcaa
    26041 caatctatca cttaacgaga actgatattg ctcgcattaa tgaactggcg gatcaattat
    26101 ttcgcagttg ggaagcgaaa tataagcgga accccacatt tacacgtaca acaacgcatt
    26161 atttggcggg aggtaagctc agtgtgtcac tcaatatcaa gtcgggacgt attgctgaat
    26221 tgcaattgac aggggatttt ttctcaggtg aagatattga agaattttgt cagaaacttg
    26281 ttgggacacg cttagacgaa caagcgattc gagaaaaaat aacagaatta actgatcagt
    26341 cgttgattta caatatctca aatgaagaaa tcgccacagc catcttagat atcccacaac
    26401 gcaatataga ttaaggtagg tgcacagata tgatggaaaa cttaaatgtt gaattgttga
    26461 atgaagctca aacgcatcaa gaggtcttac accagcaact cacgcaagtc attgatcccg
    26521 agttagggat tgatgtgttg aatttaggct tgatttacaa acttgattta aataaaaaag
    26581 gagactgtaa agtaaccatg acgcttacat caatgggctg tccgctagct gatgagatta
    26641 tgaatggtgt ccgttttgct ctgcttgatt gtgatccggt tgaatttgtt aatattgatc
    26701 tggttttttc accggcatgg agtacgagcc atatgtcgcg ttatgcgagg atttctctcg
    26761 gtgttagagc ataaaaaata aatagagaaa taaaagaagc tcccccgcaa attggggagc
    26821 ttcttcaagt agaaaggaga tgataaatga aaagaaaaac aaaaagctgt ttgtcccatc
    26881 catctgttta tatgataccg cattctggaa acggtgtcaa gtagaaatgg aaattattta
    26941 tttttttagt aaggaaatca tgaactacct ataattcagt aaccaatcgt aatgaatgag
    27001 gctatgtgtt ttgaatatta attgtcttag taagaagaca tatattgtgc ctttttttac
    27061 aatgggttaa acttgtggta tgatagagat gtaaacagat acatgaatga ttagaaaatt
    27121 gctgagagaa taagaaaggg agtcgggtaa aatgaagaaa atggttatat ttgatcctgc
    27181 tatgtgctgt tctacaggag tttgtgggcc ttctgttgat ggaaatttgc tgagggtatc
    27241 tacagtaatc aataaattaa aaaagaaaga tgtagtagtt gaaagacata atctagccaa
    27301 tgatccaaaa gcatttgtgg agaatgaatt aattaaccaa ataattgaca gtgaaggaac
    27361 agaggcactg ccgattacaa cagtagatgg agaagtagtg aaaaagaaag aataccctac
    27421 aaatgatgaa ttttgctcat ttttagatat tcctaaagca tatctggatt catcgaaaga
    27481 acaatcaaca aaaaaatgtt gttgtggaaa aggtaattgt tgctaaaagg gagtgaagtc
    27541 atatgtttga atcattcaat gcagataata ttgatttaac taaatattta ttcttcacag
    27601 gaaaaggtgg tgtcggtaaa acatcaactg cttgtgccgt ggcagttgca ctcgcagatc
    27661 aaggcaaaaa aattatgctg gtcagcacgg atccagcctc taatttgcaa gatgtgttcg
    27721 atacagaatt aaataataaa gggg
//
