LOCUS       NZ_CP040417            28377 bp    DNA     circular CON 23-APR-2024
DEFINITION  Dolosigranulum pigrum strain KPL3077 chromosome.
ACCESSION   NZ_CP040417
VERSION     NZ_CP040417.1
KEYWORDS    RefSeq.
SOURCE      Dolosigranulum pigrum
  ORGANISM  Dolosigranulum pigrum
            Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
            Dolosigranulum.
REFERENCE   1  (bases 1 to 1957024)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Eslami,S.M., Gao,W., Bomar,L., Fernandez Escapa,I., Roberts,R.J.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     The nasal commensal Dolosigranulum pigrum exhibits stable synteny
            and highly similar strain circulation over a 20-year span
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1957024)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2019) Microbiology, Forsyth Institute, 245 First
            Street, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-AUG-2018
            Assembly Method                   :: HGAP v. 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 351x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017655765.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 02:25:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,875
            CDSs (total)                      :: 1,806
            Genes (coding)                    :: 1,779
            CDSs (with protein)               :: 1,779
            Genes (RNA)                       :: 69
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 27
            CDSs (without protein)            :: 27
            Pseudo Genes (ambiguous residues) :: 0 of 27
            Pseudo Genes (frameshifted)       :: 12 of 27
            Pseudo Genes (incomplete)         :: 15 of 27
            Pseudo Genes (internal stop)      :: 6 of 27
            Pseudo Genes (multiple problems)  :: 6 of 27
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:08:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1821325
            Orig. end                         :: 1849702
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040417.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
FEATURES             Location/Qualifiers
     region          1..28377
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="6"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..28377
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28377
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18377](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..18377
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            44..874
                     /locus_tag="FE328_RS08725"
                     /old_locus_tag="FE328_08635"
     CDS             44..874
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF025001.4"
                     /locus_tag="FE328_RS08725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08635"
                     /product="AAA family ATPase"
                     /protein_id="WP_208957949.1"
                     /transl_table=11
                     /translation="MLQEKLMKTISFTAVKGGVGKTTLTYNFGEWLAAEGFQVLMIDND
                     PQSSLSQTYELYESEETVADIYRQNGVEPKIHKMKKGLDILPSTLDLERVNEELQTVSQ
                     KDFQLIGWYNEHFDNVISQYDFILIDNHPDFSTITKNAVLVSDYIISPVEPGEYSWISK
                     SNMESRFNHFIETCIDPLTRESYVTGTLKFVGNRVKHNTKTSREFLEAIAQSEQFLGWF
                     AEKELFNKSTTEHISIVEMMNRKEYRRHGDFFADTNRLFQTILSEAAKSHLGDD"
     gene            877..1119
                     /locus_tag="FE328_RS08730"
                     /old_locus_tag="FE328_08640"
     CDS             877..1119
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08640"
                     /product="hypothetical protein"
                     /protein_id="WP_143333185.1"
                     /transl_table=11
                     /translation="MSFKDKRGKFDSLLNSKGGADNTKKKMDVLPLKVNKKKKQVTFSL
                     YEITSKRITEIAAKQGYNSKSEFLDDLFESIYENM"
     gene            1308..2261
                     /locus_tag="FE328_RS08735"
                     /old_locus_tag="FE328_08645"
     CDS             1308..2261
                     /GO_process="GO:0006269 - DNA replication, synthesis of RNA
                     primer [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01446.1"
                     /locus_tag="FE328_RS08735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08645"
                     /product="DnaD domain protein"
                     /protein_id="WP_208957950.1"
                     /transl_table=11
                     /translation="MTIRRARRSTKFTMMSNHGLHNKNLSFKAKGLLAYMLSLPDDWIF
                     YQSELEERSTDGSSAIRSGLAELEEAGYLVKKRIRDEKGQLRGTDWIIQDEPVDPDEDD
                     ECEEEEGEESADKQRKISLPECDEAILGKPILENPILDNGPLLSTNNTKYLNKLNTNNT
                     KQRLYQDRSKVMYSGGDPTERGEEAFDCYRCFEENGFGTLSPFILEDLSKWFTDFRAKS
                     TPEKEIDQLIVRAMMISVKNGVRKWSYVNSILNNWFNSGLWSVEAVKVAEQQYQTNKQS
                     SDSSSSPSKGTVGGLVWGDNDNKNQEAKGKTGELNW"
     gene            2303..2521
                     /locus_tag="FE328_RS08740"
                     /old_locus_tag="FE328_08650"
     CDS             2303..2521
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08650"
                     /product="hypothetical protein"
                     /protein_id="WP_112779656.1"
                     /transl_table=11
                     /translation="MTDKDYKRHAMVMTKDGQVLYATCEYSDIKSLLEEGFMIPVLYYG
                     PDGEYFQGHVPYHNVSVIVDQAKTLTL"
     gene            2557..2793
                     /locus_tag="FE328_RS08745"
                     /old_locus_tag="FE328_08655"
     CDS             2557..2793
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08655"
                     /product="hypothetical protein"
                     /protein_id="WP_208957951.1"
                     /transl_table=11
                     /translation="MFTSRAINLIEQGMNIEAVMLNVAVREQKISCDLLEHEEFIDRLK
                     MAIEEYREVDQKKLLSTMKNCLELLTSIYMTIL"
     gene            2862..3680
                     /locus_tag="FE328_RS08750"
                     /old_locus_tag="FE328_08660"
     CDS             2862..3680
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012529.4"
                     /locus_tag="FE328_RS08750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08660"
                     /product="ATP-binding protein"
                     /protein_id="WP_208957952.1"
                     /transl_table=11
                     /translation="MQAMKFRELENVKLLKERCDKHDEPLRQIYDGEPYCQQCAMAELK
                     RAEEEKIKQLTKESQRTRVQGYLKRKSLLHDESLKRATFDQFVASKGTEAYQNKQKSRM
                     IAKDYLDDKHYNTLLSGDVGVGKSHLAMSILLAVNEYSDPFRRCAFISVADMINQIKNS
                     FNDPQSRYSKQYFMTIAKEADVLVLDDIGAETGHIGTHKQATDFVNEVLYSLLNYRSTK
                     PTIFTTNMTSKHFEQLYDDKVLSRIGRGTAINQSLITFKHTPDKRAMLDF"
     misc_feature    complement(3742..3757)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.36"
                     /tool="antismash"
     misc_feature    3846..3864
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 26.18"
                     /tool="antismash"
     gene            4037..4570
                     /locus_tag="FE328_RS08755"
                     /old_locus_tag="FE328_08665"
     CDS             4037..4570
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08665"
                     /product="hypothetical protein"
                     /protein_id="WP_208954496.1"
                     /transl_table=11
                     /translation="MMEFSIFDEVIDDPQVEIDEKQTIQRARYVLSLYKKKLYRQANIK
                     QDPQVTSQLSLTPPTFSSGLSDQMAKRLEVEETAQDIITAIFKAINQMYVTTAVPTLYY
                     RQLLYYRFLDFEVHSVIAVRERLAGEFPRRIEYDYNPVMLDKHVYYHDERQALIAFAQA
                     FHSEHAQESLVVYK"
     gene            4743..4940
                     /locus_tag="FE328_RS08760"
                     /old_locus_tag="FE328_08670"
     CDS             4743..4940
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004896709.1"
                     /locus_tag="FE328_RS08760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08670"
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_208957953.1"
                     /transl_table=11
                     /translation="MDNTKESILDRNESDVEVLDFDFEVIEMDDVSVLPETAASSGSSG
                     DNTYSTCGSCSCCSSSSCCT"
     gene            5095..6231
                     /locus_tag="FE328_RS08765"
                     /old_locus_tag="FE328_08675"
     CDS             5095..6231
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08675"
                     /product="hypothetical protein"
                     /protein_id="WP_208957954.1"
                     /transl_table=11
                     /translation="MQVDDHNLNHTRYLDIINIIRNYSNEINLFYPSELEAIYFRLMRN
                     IELIHLNKKIIPQEYNQSLEVKGIPFFNGVKASFTGLYPTNLLFTGIRHIVVDEEISDV
                     IIDNLNLLSNINSSQIYYDPLGFESLDIDFGLRKMLVKGKCIEEYSLNGELLNSYDACY
                     ISFNNLRTITSREILNTELLVYFSNNQEFNEFLNVFKNFYEGRRIKIKYLLASYKNEST
                     VGLIFNKELDSTINMSISQLNKYQPNNITYGEIYNNIKKERIMTSLKNHQATYFNESID
                     NSQKIKEEINSHDSDLINSFPEIPRVLRIKNIVKSLLKHLIEIDKITSCEDILELDTLN
                     EKYFFRINDYFYMIDENKMKFYNLKREDYYTFLKEWRG"
     gene            6233..7480
                     /locus_tag="FE328_RS08770"
                     /old_locus_tag="FE328_08680"
     CDS             6233..7480
                     /NRPS_PKS="Domain: Aminotran_3 (23-353). E-value: 2.1e-69.
                     Score: 226.0. Matches aSDomain:
                     nrpspksdomains_FE328_RS08770_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012428.4"
                     /locus_tag="FE328_RS08770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08680"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_208957955.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.2e-72, bitscore:
                     240.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKGQIFSSVEKKYYDKMIKIANTDKIYIIDEKGKEYIDAISGLW
                     NKNLGYKVPEISQKIIEQFEICESINPWLSTTQLNESYSKDLLDFSGYSEGSIYLSLSG
                     SESLEVAIKAARKYQVLQRNKEKKIILTFDNGYHGGTIGAWSISGNQRGLIQPYSPLMN
                     GTAFVPFIHDDKTFQSFCKYINAYGEKTAAFIIEPTLGFGGGFEIPVKYMIKIQEICKI
                     NDILLIFDEVSTGFYRTGKRFAFEKYKLRPDILCLSKGLNNGVLPFGATIFKEKIFGKI
                     RKNDMFAHFSTQDYNPLLTASGKAVLDIYKENDFETNNEMLSNEFKQNIKLTLQPYLER
                     LFIDGLFITMEFKKITSYKDVRRFFYKLIENGLIVYTYSNHYGSGLILAPMYITSKEEC
                     QEIIRIIERTYLEWNE"
     aSDomain        6302..7291
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FE328_RS08770_Aminotran_3.1"
                     /evalue="2.10E-69"
                     /label="FE328_RS08770_Aminotran_3.1"
                     /locus_tag="FE328_RS08770"
                     /protein_end="353"
                     /protein_start="23"
                     /score="226.0"
                     /tool="antismash"
                     /translation="TDKIYIIDEKGKEYIDAISGLWNKNLGYKVPEISQKIIEQFEICE
                     SINPWLSTTQLNESYSKDLLDFSGYSEGSIYLSLSGSESLEVAIKAARKYQVLQRNKEK
                     KIILTFDNGYHGGTIGAWSISGNQRGLIQPYSPLMNGTAFVPFIHDDKTFQSFCKYINA
                     YGEKTAAFIIEPTLGFGGGFEIPVKYMIKIQEICKINDILLIFDEVSTGFYRTGKRFAF
                     EKYKLRPDILCLSKGLNNGVLPFGATIFKEKIFGKIRKNDMFAHFSTQDYNPLLTASGK
                     AVLDIYKENDFETNNEMLSNEFKQNIKLTLQPYLERLFIDGLFITMEFK"
     gene            7477..8211
                     /locus_tag="FE328_RS08775"
                     /old_locus_tag="FE328_08685"
     CDS             7477..8211
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="FE328_RS08775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08685"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_208957956.1"
                     /transl_table=11
                     /translation="MKKAIVTGASSEIGKATILRLIEEGYYILACDLEVMRDKFYDNEI
                     SSQQELIKFIPLDLKNTDLRNAVIKNISNNQVDLCINIAGKNILKSFYEWDEESLKDVF
                     DINFIYTTLFIKEVAVKFIEYNTPGKIILISSQHGIVANKERIPYCVSKGMLAQLTRAL
                     ALELAPYSIRVNSVSPTFVKTKDNKKLLETPLMYYEAHDQIPLKKYAEASDVASAICFL
                     ANDENNMITGHDLVVDGGWTIQ"
     gene            8224..8529
                     /locus_tag="FE328_RS08780"
                     /old_locus_tag="FE328_08690"
     CDS             8224..8529
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /locus_tag="FE328_RS08780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08690"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_208957957.1"
                     /transl_table=11
                     /translation="MNKRFLKFRIRNNMTIEQVSKELNVSEGDVLAWEKGKYYPPLDVS
                     MKLCELYNIRIDELCGTQENVNHQYNNILTILMENWWKLLAMFSVLAYLINSLNKI"
     gene            8548..9237
                     /locus_tag="FE328_RS08785"
                     /old_locus_tag="FE328_08695"
     CDS             8548..9237
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="FE328_RS08785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08695"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_077862412.1"
                     /transl_table=11
                     /translation="MTSLVEVESLSKKYGKEVILEDINFTINQGDKIALIGKNGSGKTT
                     LLNIITKLQKETSGKVIYNLNEKNFYMNFGIQMQDGVFDERLTIHDYCLLLEKLFDVEG
                     KTDKYLKDFELEDKRKKKINTLSGGEKQKFNIICALLHDPEILIFDEVSTGLDTINRSV
                     IKKYIKKFAEKKTLILVSHYMEEIEQLCERVICINNKHIIVDEDIIEIRNKYGSLEKFY
                     VSEVGGQ"
     gene            9239..9979
                     /locus_tag="FE328_RS08790"
                     /old_locus_tag="FE328_08700"
     CDS             9239..9979
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="FE328_RS08790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08700"
                     /product="ABC transporter permease"
                     /protein_id="WP_172764179.1"
                     /transl_table=11
                     /translation="MNKLKGLFNLELKKTIRTPIIMFFSILAPQFFIYIQSSLSEEVIM
                     NGQSIPSIDYSFPMFLYLAVIVVGIGNVGVGMSYNRLIKFFTRLKVSNVRAIDFIVANF
                     FVQLSIAVLSTLLLFLSSILVLDMSLEGRNWTIFFLVFFLVWIMTYLIGIVLANIVKDA
                     KTSQSVSLIVYFFLIFFSGVTYPIELMPELLQKISKLLPTYYGLRILQEAWYINGNIDT
                     THLIIVIGSTVILFVISLKIFKFD"
     gene            10001..12571
                     /locus_tag="FE328_RS08795"
                     /old_locus_tag="FE328_08705"
     CDS             10001..12571
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="FE328_RS08795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08705"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_208957958.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.8e-09, bitscore:
                     31.6, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVNPIILERESSFSNKWLSLFSFNEVIEYFDEIESIEVKMESLK
                     EEIINDLEDLIGETSGDIKLTLINLKRNLYNNRKIKLPENTTSLDSHEAWSNIKREIKK
                     LAYFRNKSKVKREELDSVLKENFIKERRSLWKEAKSNIWMKNALNFLSPNSIISLKNYL
                     ETNVDEHRSKEKKLDYLLLKVLTRASTKTSPFSTLTRNCITIRDIEKEQFNKVEYKETE
                     KIYTQVNYKLLLEYYEELKYRDIYFKGLSFFINDTTLVFDNILYVTSLVNHKDKPKVFE
                     TTDLLQKFKINNFLSDLIDIFKTNSSEFLTYQEIFDELETKGHKNIHSSLKFFAKKKVI
                     LTKENLKEEYNIIDNLLELISPCQEDKLINNVVMMLKEVKERIRKINEIPFNSDEEIYL
                     VRKKLKEINKLLNIDPIPQKNFLVQDYFLNQLKESINLSERQVQTLKKILYLIKIFDGE
                     LYLQLLIGDWISKKYGTDFISIKENVNVIKEIVNIIIQNVDNISNLNLSPLNLNSEILF
                     LTKLSEVRNQFIEMIISSDDRKTINISEDILDNMISNMDFLKEYDSSNSFFFQVNKDKK
                     LVINNIYTGYLSYFNRFLYFYPEVMDIPTVKSYLNFLNEEKRIADIFNIYGFNANIRPN
                     ITEKVIQIPNKTVNFDKENQKCIQMDELTLKIDEELGILKFYEDKNKKEIKPIFMGSVI
                     KSAIPSIAATLDTLSNNGSLQLSLSKQIINYHILKDDFFEKKIPEVTVSDTVILSREKY
                     IFKFEVFKNARKLEDIEKLKWLVQFFRDKGMGQAFFVSKATIKESSERKYVEIEKPQYY
                     NFTSISFCRLFFRENKSSDYVVFEKCNPEIKENTVTEYLAEITN"
     gene            12602..13675
                     /locus_tag="FE328_RS08800"
                     /old_locus_tag="FE328_08710"
     CDS             12602..13675
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08710"
                     /product="hypothetical protein"
                     /protein_id="WP_208957959.1"
                     /transl_table=11
                     /translation="MIYRIRVFCFDIKYRQNLVLESLDYVKEKNIKLISIKKRWENGFH
                     IEYILESRFLKELKGYLYDQLTNIPDIPKKVFDKMLHQIRLLKDIENAPAESKKVKENK
                     QIVIESVGTNLSNIYDNESYLEIQKIKQNWIKDFTGEIFESNKEQKNSILLKMMLIAAN
                     KFHFDDDYKGFKFGVLSYYSHYQGYINHIEQFPPLYKQKYKDMIFHGVSTTKKSLKDLD
                     DWLTELSKQSLNEDILINWSKMLDQLMEKHRDLVDKKKIYSGNDYEIEQYLDKMNNVSN
                     FHKKFTLNKNFKWFISSKEFKVYRGTINQMYEVLTFLSISSLQRTIYCGGISEYIFESY
                     KFDIDELLKDINEKYGY"
     gene            13691..14773
                     /locus_tag="FE328_RS08805"
                     /old_locus_tag="FE328_08715"
     CDS             13691..14773
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08715"
                     /product="hypothetical protein"
                     /protein_id="WP_208957960.1"
                     /transl_table=11
                     /translation="MKGVYFFLSENDTIIFRSLKTKVKIRDQKLYSYFLGKYLIKPKEI
                     NFIKKNEIPPTLLSVLGFKEEDLNKKTQNNTNNSTEIYRKIIDKSKYPLNKIDEKLIEY
                     IDLEKLGIQNCTINLIKGEKVININVDEYLRKLSLDSGEDHIRLDWNHLNWNEKVKISN
                     ECVNQKKELSHLYSEITYSKSPQYNEAYLFKEDPKQSMIFVGEDILEVTQSIITYLVNK
                     NTKLICANSRKQAEKFLRKNQLSVQKQKMKRYTEILEGFDVYKYLHQDSHEYYLEMFFG
                     VNKVYSELFNDLDDLNTRKSKVIDLIRNQLQIQQPNKLKIIWNYDVFNRNVYKNNWEVF
                     SNDKLKKLNLKLYNERTISN"
     gene            14770..16668
                     /locus_tag="FE328_RS08810"
                     /old_locus_tag="FE328_08720"
     CDS             14770..16668
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="FE328_RS08810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08720"
                     /product="YcaO-like family protein"
                     /protein_id="WP_244325335.1"
                     /sec_met_domain="TIGR03604 (E-value: 6.7e-87, bitscore:
                     288.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.6e-64, bitscore: 215.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNIYIISNDSHFQKMFLKSTNNIVTPINIKEVKRIEKESIVLHL
                     SDFNTLSLDKVIANNLNGKLFLRANIIFDQVFIGPLSNQNSACLECLELYNKNNNKESD
                     FLLFKDIKTPIDHQNISYRKITELIDLIIEGWESFLNQLIILSPKITKRISLVQHYQCT
                     TCSHLKSNSAINAKVKYSNNKKKSKDIYRTKEKFNVNNFYKFTDKNFGFFHHQYREYIS
                     NYAPLNCVEVNVDDSYEAGWGRTYTVYESTVSAYLEALERYANSYNRRYNRLLTKSYEE
                     IKSIAVDPKIFTLHNDEYRDNSYKFNNYTEKLEIDWIYGQNLITKEQVLIPSQMVFYRD
                     LTKKDREKRFVYETSNGCALGSSSEEAIFYGILEIIERDSFLTSWYLKEKVTRISENSL
                     PKRIQEIIKKLNENKQNLYLYDITKELGIPVVWALFIDENKNAKVKTFSAAGCHLDPYK
                     AIEAAVFEVITSVPTFVRSLDNQEIKEKMEMMQTDYSLIQDIDDHIIYHAYDEYQSKLE
                     FLLNDNPIMDIEEIYKKDIKEKFNQEMLTLDLKILLDLVKTNYSDVFAVNLTDKVLQNF
                     ELEAYKVLIPGLLNMSFGHSHRRVNINRLKKYGRKIGIDPDNITLETINQIPHPFP"
     gene            16713..17612
                     /locus_tag="FE328_RS08815"
                     /old_locus_tag="FE328_08725"
     CDS             16713..17612
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF025394.4"
                     /locus_tag="FE328_RS08815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08725"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_208957961.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 7.5e-32, bitscore:
                     107.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKIEKEYINDWVSLHFYYYDQYKYDQLILKLLEFLKSEKNNLKI
                     TQYFFIRYWEGGPHIRLRYKTVNSNEYREEVFRKLKEIADDFWKNHPTTVILNESDYQK
                     VIKEVPDSNTESLEYLIPSETIKPIKYDPEFERYGNNRLMIKNESFFEISSDISVLLLK
                     FLLNKDSSYFHKLIVTTATLKLLIEITLARYTSETKDILNHMIDYWQNNNIFLDKTIVS
                     HLMQHQNQIDKFCKFLKKYAKEEMIKIQKINEEIYSLSSEDDFYYGVISSQFHMLANRL
                     GIFPKYEIVCLEVLKTFI"
     gene            17622..18377
                     /locus_tag="FE328_RS08820"
                     /old_locus_tag="FE328_08730"
     CDS             17622..18377
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03605.1"
                     /locus_tag="FE328_RS08820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08730"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_208957962.1"
                     /sec_met_domain="PF00881 (E-value: 1.6e-05, bitscore: 21.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDYFFDINEFNRMRKSMETPSFLWGKTKPRNDFFYKDNNSKTDI
                     SFDVVDSPLPSLSLEEALINRKSSLLNTFTGNMSKNEVLKYLNSAFNTTGKKLIGDNTE
                     IKRKPYPTAGGLNTIQPYVFINNVDGLSTGLYQVNENGITYKKRISYLDLETISPLTFF
                     KNDSRNNTFKNVNLIVILIAKYNNIFSKYGFLSYKLLYLEAGHIAQNLQLLSSVMNLRS
                     LPLGGCFNDKIEKIVPETEFEYLYSMAVG"
     gene            18377..19078
                     /locus_tag="FE328_RS08825"
                     /old_locus_tag="FE328_08735"
     CDS             18377..19078
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08735"
                     /product="hypothetical protein"
                     /protein_id="WP_208957963.1"
                     /transl_table=11
                     /translation="MKYYYLDPIYIIKIDQDNILNFYNLETKNINLRLRGSNKINESTL
                     YKVPEHILKERFSNNYRKFYYDYEQYEYKKEIFNFLSGNNSIEYYSSIQSEIDQCFFHF
                     EAINKRDHHFLSQLNINSKREYKMNIMPFESDKEKNDEEDKINFYYEKIDEIEFSLGPI
                     VFGRNYMKVSQKDIKYSSLYPTFEENLKTEILNFFLDKVNTYETSYSNCLYQQNRFGKG
                     VVYKEEYFRPF"
     misc_feature    19618..19633
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            19949..20881
                     /locus_tag="FE328_RS08830"
                     /old_locus_tag="FE328_08745"
     CDS             19949..20881
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004637043.1"
                     /locus_tag="FE328_RS08830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08745"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_208957964.1"
                     /transl_table=11
                     /translation="MIILEDVNKQYTIKSGFIHKNIQTVDALKHINLTIDKGETIGLIG
                     LNGAGKSTLLKLILGILTPNDGSVKLFGKTPVDHRKLLMKDVGVVFGQRPQLRWDVSPK
                     DAYDLNKEIYKIDTEQYQKNLHYYADKLRVRDFWDRPVRTLSLGQKMRADLLAALLHNP
                     SLLILDEPTIGMDVVSRNVMLELIKELKQQVTILFTSHNLSDVYELCDRFVILNHGQVV
                     IDEKKSVISQRIGFVSIQVTIAESTLNFEPANFSITKANDYEYRIEDIPKEQLKEVLND
                     LYERNTIEELSIQNNNLEAILNQLEGANV"
     gene            20878..21633
                     /locus_tag="FE328_RS08835"
                     /old_locus_tag="FE328_08750"
     CDS             20878..21633
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017946.4"
                     /locus_tag="FE328_RS08835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08750"
                     /product="ABC-2 family transporter protein"
                     /protein_id="WP_208957965.1"
                     /transl_table=11
                     /translation="MKQLIKIGIKKITNYTDYLTILLLKNIIYLLVQWALWTTILRYDD
                     SLGSIHSIMSYFLIVQGLDTLYPYTSMDVSDDIKSGDIINKLCKPVSLVQQYFYEAFGS
                     SITKFCTVVGVNFIALIFFAQSISGTKLLGLFLLIIAGYLLNFSIELLFGSIAFFTQSI
                     WGIESLKSAVKVIFAGSIVPIYYYPKWLVQIANLLPFSYTQGNIAAYFNGERTLFSVLG
                     IQVIYVVVFMLGAQMILRYGLRQLSINGG"
     gene            21636..22430
                     /locus_tag="FE328_RS08840"
                     /old_locus_tag="FE328_08755"
     CDS             21636..22430
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017946.4"
                     /locus_tag="FE328_RS08840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08755"
                     /product="ABC-2 family transporter protein"
                     /protein_id="WP_112786907.1"
                     /transl_table=11
                     /translation="MSVIKDYTRLFFCMLRINIKGLKSYGQDFFVGIIAMIIKNIANII
                     GVFMIYEIIPVINGWSLPELLFLYAFSTISFSFWRCLFMNTLNVSYYVRNGELDSFLIK
                     PIDPLFQIFMEGFDDDAWGDLLVGFIVCMMAMAQLQLPWWVFLLVVITGLFSSLIFASF
                     SIMGSLLSLKVARDSDLSDMPYIVFDLIRYPISIYGQVMYNVFVFFFPIAWISYLPAKA
                     LLTDHSQGVLYSGISIGISLGLFVLCYVIWSSYLKHYRSTGT"
     gene            complement(22913..23606)
                     /locus_tag="FE328_RS08845"
                     /old_locus_tag="FE328_08760"
                     /pseudo=""
     CDS             complement(22913..23606)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030310.1"
                     /locus_tag="FE328_RS08845"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="FE328_08760"
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNKAKLTALCHKISKQTGLTFNSVMTYYFLEVI"
     gene            complement(23603..24193)
                     /locus_tag="FE328_RS08850"
                     /old_locus_tag="FE328_08765"
     CDS             complement(23603..24193)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037247.1"
                     /locus_tag="FE328_RS08850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08765"
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="WP_208958338.1"
                     /transl_table=11
                     /translation="MTKKQKLLRYLEENNGIITHQDCQKLDIPTVYLTRLEKKGTIFRV
                     EQGIYLTPNGDYDEYYFFQYRFSKAIFSYISALYLQGLTDEIPQYFEVTVARGYRFNDP
                     PSNLNIHFVSKEYSSLGITSVETPMGNTVQVYDLERTLCDFIINREKIDSELFVKTLQL
                     YADYPKKNTAKLYKYATEMHIIKETKRTLEVLI"
     gene            24628..24843
                     /locus_tag="FE328_RS08855"
                     /old_locus_tag="FE328_08770"
     CDS             24628..24843
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08770"
                     /product="hypothetical protein"
                     /protein_id="WP_208957966.1"
                     /transl_table=11
                     /translation="MKRQEMVQAYLRCSECGLLMIIPRRAARKKKVGHVKHMYCSQCKC
                     KRAFIEEDGYYQYDPKEFINKRVEIK"
     gene            24970..25269
                     /locus_tag="FE328_RS08860"
                     /old_locus_tag="FE328_08775"
     CDS             24970..25269
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08775"
                     /product="hypothetical protein"
                     /protein_id="WP_208957967.1"
                     /transl_table=11
                     /translation="MVKSIVKKHEAILEAKGIDPDDWHEETFKSVMAEMTYRPTKHQRN
                     QLIEFKRKEEIEEFEEEMIELLKEKTEREEKIPSSEKQNSLINSNSDEPEGGEQ"
     gene            25355..25693
                     /locus_tag="FE328_RS08865"
                     /old_locus_tag="FE328_08780"
     CDS             25355..25693
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016820.4"
                     /locus_tag="FE328_RS08865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_08780"
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_208957968.1"
                     /transl_table=11
                     /translation="MFSNLQQFITNFIQQVQGLSPWLAAGCAVIVALMYAFGGQQASQM
                     AKSWGWKIVVGLFVIWGVAAIINTLISMFGADGSVSEIDISSLEVIKDTVETLGVGQTV
                     AMAFIGLL"
     gene            25777..28098
                     /locus_tag="FE328_RS08870"
                     /old_locus_tag="FE328_08785"
     CDS             25777..28098
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS08870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_08785"
                     /product="hypothetical protein"
                     /protein_id="WP_208957969.1"
                     /transl_table=11
                     /translation="MSLKDFFTNIFSKKEKEEADELEQRSSCETKADDFEEIRSDNSSN
                     YVLNDTDGNDEKSDQQKDNQNGSDDENAPLDNEEAVNNAFKDDSKQKGSNKEGDEHEDS
                     EKLVDEIDQQEEQNKKQVAENNDEEKKWQERSWSQEVVDNEADEAATLKQEQVSEEKHV
                     QFINVEAYKDLSRLSDMIERHKHKVGNEALLSRLSLIEDSADFSTLDEYKRDYALKHIQ
                     SSDIQDITQTFVDNLDSLIETTQLNLVTKHDEVLTTNYELRALDAIEFELDDLQDNKDQ
                     AISQYKEKQNSRYDKKIETFKKKQEKELEAFKRKQETKFLETKEELINRRDNNIELYEK
                     EKEKEYNRKYKAKLNKQRYTEEQLGAKELNPIKQDVLQEFQSELKEASNKVQEKLKPKL
                     NEIREGINQKEHDWIQEITEQKRLSEERKKRRIEEERLALQKEEFELERKERLEKLEMA
                     KEAQRLQALERSDDHQKEIERLQRELEKHEKSTAQMNEVLLAKLINQLDGEQEADKDLK
                     SDDSIKKPEVKPDNYYRKFYWIVSLIVLILVGLALWFFVLNDSRLPSSKSSNVSDVAVV
                     ETAKQAGEEAEHDESDYIRRGSDDNVITDEHEDIEDKADDIPSAEVESEEETAEQATRE
                     ELKEKVQILEKELERWTSVDNMNGEPISFDEALERGDFQAAIKTIDLDDDESFNRLTDE
                     MRRQGELEVLQVFNERYDTTYGLMDQHYLSDNIWGVWNEMMWLTNDERVHMGDHRKQDV
                     ANYLWDNHFYYYSRWLINAH"
ORIGIN
        1 ataatcatga gcaacaaact aaaagaaaga ggagttgata gatttgcttc aagagaagtt
       61 aatgaagacg attagtttta cggcagttaa gggtggtgta ggaaaaacaa ctctaactta
      121 taattttggc gaatggttgg cagctgaagg ctttcaggtt ctgatgattg acaatgaccc
      181 gcaatcatca ctatcgcaaa catatgagct atacgagtca gaggagacag ttgctgatat
      241 ctatcgtcag aacggcgtag aacccaaaat tcataagatg aaaaagggct tagatatctt
      301 gccatcaacg ttggatttag agcgagtaaa tgaggaactt cagacggtca gtcagaaaga
      361 tttccagtta atcggctggt ataatgagca ttttgataat gtaattagtc aatatgattt
      421 tatcctaatc gataatcatc ctgatttttc aacgattaca aagaatgccg tattagtaag
      481 tgattatatc attagccccg ttgaaccggg cgaatatagt tggatatcga agagtaatat
      541 ggaaagtcgc tttaaccact ttatcgagac ttgtattgat ccattgacaa gagaatctta
      601 cgtcacaggg acgttaaagt ttgttgggaa tcgagtcaag cataatacaa aaacatctag
      661 agaattctta gaggcgatcg ctcagtcaga gcagtttctt ggatggtttg ctgaaaaaga
      721 attatttaat aaaagcacaa ccgagcatat ctcgattgtt gagatgatga atcgaaaaga
      781 atacaggcga catggcgact tttttgcaga cacaaaccgg ttattccaaa ccatattatc
      841 tgaagcagca aagagtcact taggagatga ttgattatga gctttaaaga taagcgaggc
      901 aagttcgatt cactcctcaa ttcaaaaggc ggagcagata acacgaagaa aaagatggac
      961 gttttgccat taaaagttaa caagaagaaa aaacaggtga cgtttagtct ttacgaaatt
     1021 actagtaaac gaattaccga aattgctgca aaacagggat ataactcaaa atcagagttc
     1081 ttggatgacc tgttcgagag tatttacgaa aatatgtaaa tagttattga taatcataag
     1141 tacattacta tgtataaagt tatgtaacat tatatgtatg tatctataca aggatataaa
     1201 taacaatata cgtaaggtct tcaataatat catgaataaa atgataaaag ttaggaaata
     1261 caacatgtca atttagttac aaaaagatac ttctcaggag gaaaactatg acgatcagac
     1321 gagcaagacg aagtacaaaa tttacgatga tgagcaacca cggattacac aataaaaatt
     1381 tgtctttcaa ggcaaagggg ttgctggcat acatgctatc tctaccagat gattggatct
     1441 tttatcaaag tgaattagag gagcgctcta ctgatggctc atcagcgatc cgtagcgggt
     1501 tagccgagct tgaggaagcg ggctatctgg ttaaaaaacg aattcgagac gaaaaagggc
     1561 aattgcgagg gacagactgg attattcaag atgaaccggt tgaccctgat gaagatgatg
     1621 aatgtgagga agaggagggt gaagagagtg ccgacaaaca gcgaaaaata agtctaccag
     1681 aatgcgatga ggctatttta ggaaaaccta tattagaaaa tccaatattg gataatggcc
     1741 cactactaag tactaataat actaaatact taaataaact aaatactaac aatactaaac
     1801 aacgattata tcaagataga tctaaggtga tgtatagtgg cggtgatcca acggaaagag
     1861 gtgaggaggc atttgattgt taccgttgtt ttgaggagaa cgggtttgga acgctaagcc
     1921 cctttattct tgaggaccta tcgaagtggt ttactgactt cagagcaaaa agcacgccag
     1981 aaaaagaaat cgatcagctt atagttcgag cgatgatgat ttctgttaaa aatggtgttc
     2041 gcaagtggtc ttacgtcaat tctatcctga ataattggtt taatagcggt ctatggagcg
     2101 ttgaagccgt aaaagtagct gaacagcagt atcaaactaa taaacagtcg tctgacagct
     2161 cttcaagtcc ttcaaaggga acggtaggtg gtttagtctg gggagataac gacaacaaaa
     2221 atcaagaagc taaaggtaaa acaggtgaac ttaactggtg atgttaagct gtttagacaa
     2281 aaataaaaag gagttaaaaa acatgactga caaagattat aaacggcatg caatggtgat
     2341 gacaaaagat gggcaagtgc tgtacgcaac ttgtgagtat agcgatatta agagcttgct
     2401 ggaagaaggc tttatgattc cagtactgta ttatggtcct gatggagaat attttcaagg
     2461 gcatgtacct tatcacaacg tatcagtgat tgtcgaccaa gccaagacct tgacgctata
     2521 gaagagtcaa gaagactagt caaggagttg attgatgtgt ttacaagcag agcgataaac
     2581 ctaattgaac aagggatgaa tattgaagca gtaatgttaa acgttgcggt gagagaacag
     2641 aaaatatctt gcgatttact ggagcatgag gagtttatag accggcttaa aatggcgata
     2701 gaagagtata gagaggtaga tcaaaagaaa ttattatcaa ctatgaagaa ttgcttagag
     2761 ttgttaacca gcatatatat gacgatccta taattatcat ggattatcca gttaaatatg
     2821 gcggatagaa cgttaagagt aagaacttag ggggactgat tatgcaagca atgaagttta
     2881 gagagctaga gaatgtgaag ctactcaaag agcggtgtga taagcatgac gagccgttgc
     2941 gacaaattta cgatggcgaa ccatattgcc aacaatgtgc tatggcagaa ctaaagcgag
     3001 cggaagaaga gaaaataaaa cagttgacga aagagagtca acggacgagg gtacaaggct
     3061 acttgaagcg gaaatcattg cttcatgacg agtcgttgaa acgagcgaca tttgaccaat
     3121 ttgtcgctag taaagggaca gaagcctatc agaacaagca gaaatcccgt atgattgcta
     3181 aagattacct agatgataag cactataaca ccttattaag cggcgatgta ggcgttggta
     3241 agtcacatct agcgatgagc attttactag ccgtgaacga atattctgac ccgtttcgtc
     3301 gatgtgcttt tatctcggtg gcagatatga ttaatcaaat caaaaatagc ttcaatgatc
     3361 cacagtcacg ctacagcaag caatatttta tgacgatcgc taaagaagct gacgtgttag
     3421 tgctagatga tattggagct gaaactggcc atatcggcac acacaaacaa gcaacagatt
     3481 ttgttaacga agtgctgtat agcctgttga attatcggtc aactaaaccg acaattttta
     3541 cgacaaacat gacctcaaag cattttgaac agttatatga tgacaaagtg ctgtcgagaa
     3601 tagggagagg aacagccatt aatcagtcat tgattacatt taagcataca ccggacaaac
     3661 gagctatgtt agatttttag gaaaaactat tatgcaggtg aggagataga taaagatatg
     3721 tgaggtaatc cgacacttgg tttgacaaga tggtcagtaa tacaggggaa atacgtttac
     3781 gataaaaaat agtgtagagg agatgaagac ttatgaagta tcgtggagta ggaaaaacgt
     3841 ctttaaaagt atatacagta ggctcgtatg cagaggtact tcggtttatc aataccaagt
     3901 acccaagtta caatgaacat caacagcaac gcaaccgata ctggcagagc ctatttttat
     3961 agagcctata aaaccgaatg cgttcaagta tgaaccaata aagccactac cttttccaga
     4021 ggagatgtga tagcgaatga tggaattttc tatttttgat gaagtaattg atgacccaca
     4081 agttgagatt gatgaaaaac aaaccattca acgggctcgt tatgttttat cactatacaa
     4141 aaagaaatta tacagacaag caaatattaa gcaagaccca caagttacaa gtcaattaag
     4201 cctgacaccg cctacatttt catcaggact atctgaccaa atggctaaga gattggaagt
     4261 tgaagaaaca gcacaggata ttattaccgc gatctttaag gcaatcaatc aaatgtatgt
     4321 gactaccgct gtaccaacac tgtattatcg ccaattatta tattatcggt ttttggattt
     4381 tgaagtacat tcagtgatag cggtgcgtga acgtttggcg ggagaattcc ctagacgtat
     4441 tgagtatgac tataatcccg ttatgttaga taaacacgtt tattaccatg atgaacgaca
     4501 agcactcatc gcttttgcgc aggcatttca ctctgagcat gcccaagagt ccttggtggt
     4561 atataagtaa taaaaaaata agtattttca gaaattactg agtgttgcaa ttcactttac
     4621 aacacaccac aagaagacaa ataaaataat caatagttaa tttttgcaat taatatttaa
     4681 atatggtaat atcaaattga gcattgaaac tgcttacaaa atatgagagg aggatactca
     4741 tcatggataa cacaaaggaa tctattttag accgcaatga atcagatgtg gaagttctag
     4801 attttgattt tgaagttatt gaaatggatg atgtttcagt cctacctgaa actgctgctt
     4861 caagtggaag ctcaggcgat aatacctact ccacatgtgg atcttgctct tgctgttctt
     4921 catcttcttg ttgtacttag agaagtgtgt agagtctttg tgaatggtaa tcttggtcag
     4981 cgtcagctag tatgattgaa attactagct gaccggatta ctattttatt taaatccgag
     5041 atggtgctag ataatgaaaa tagaactata tcaaaaaata atggacttgt tggagtgcaa
     5101 gttgatgatc ataatttaaa tcatactaga tatttagata tcataaatat tattaggaac
     5161 tattcgaatg aaattaattt attttaccct agtgagttag aagcgattta ttttagatta
     5221 atgcgtaata tagaattaat tcatcttaat aagaaaatta ttcctcaaga atataatcag
     5281 tcacttgaag ttaagggaat accatttttc aatggagtga aagcctcatt cactggttta
     5341 tatcctacta atttgttatt tactggaata cgacacattg tggtcgatga agaaataagt
     5401 gatgtaataa tagataattt aaatttactt agtaatatta acagttctca aatttattat
     5461 gatccgttgg gttttgaatc ccttgatata gattttggtt taagaaaaat gttagtaaag
     5521 ggtaagtgta tagaagaata tagtttaaat ggtgaattat taaacagcta tgatgcttgc
     5581 tatatttcat tcaataattt aagaactatc acttccagag aaatattaaa cactgaattg
     5641 ctagtttatt tctcaaataa tcaggagttc aatgagtttc taaatgtatt taagaatttt
     5701 tatgagggta gaagaataaa aataaaatat ttacttgctt catataaaaa tgaaagtaca
     5761 gtaggtttga tttttaataa agaactagat agtacaatta atatgtcaat atctcaatta
     5821 aataaatatc aaccaaataa tattacttac ggcgaaatct ataataacat aaaaaaagag
     5881 cggataatga ctagtttaaa aaatcaccaa gctacttatt ttaatgaaag tattgataac
     5941 tcacaaaaaa ttaaagaaga aataaatagc catgattcag atcttataaa tagttttcca
     6001 gaaattccta gagtacttag aataaaaaat atagttaagt ctttgttaaa acatttgata
     6061 gaaatagata aaataacctc ttgcgaagac attctcgaac ttgatacgtt aaatgaaaaa
     6121 tattttttta gaattaatga ttacttttac atgatagatg aaaataaaat gaagttttat
     6181 aatttgaaaa gagaagacta ttatacattt ttgaaagaat ggaggggata gagtgttgaa
     6241 aggacagata ttttcatcag tagaaaaaaa gtattatgac aaaatgatta aaatagctaa
     6301 tacagataaa atttatatta ttgatgaaaa agggaaagaa tacattgatg caattagcgg
     6361 attatggaat aaaaatttag gttataaagt accagagatt tctcaaaaaa taattgaaca
     6421 attcgaaata tgtgagtcta taaatccttg gctgtcaact acccagttaa atgaatcgta
     6481 ctctaaagat ttattggatt tttcaggata ttctgaaggc agtatttatt taagtctgtc
     6541 aggatcagaa agcttagagg tagcaattaa agctgccaga aaatatcaag ttttacaaag
     6601 aaataaagag aaaaaaataa tacttacttt cgataatgga tatcatggag gaactatagg
     6661 agcatggagt atatctggaa atcaaagagg attaattcaa ccgtatagtc cattaatgaa
     6721 tggtactgcg tttgttccct ttatacatga tgataaaaca tttcaaagtt tttgtaaata
     6781 tattaatgcg tacggagaaa agacagccgc ttttattatt gaaccaacct taggatttgg
     6841 aggtgggttt gaaatcccag taaaatatat gattaaaatt caagaaattt gtaaaataaa
     6901 cgatattctt cttatttttg atgaagtatc cacaggtttc tatagaacag gaaaacgttt
     6961 tgcttttgaa aaatataaac tgagacctga tatattgtgt ctttctaaag gattaaataa
     7021 tggagtttta ccttttggag ctactatatt taaagaaaaa attttcggaa aaatacgtaa
     7081 gaatgatatg tttgcacatt tttcaacaca ggattacaat cctttattaa ctgcatcagg
     7141 taaagcagta ttagatatat acaaggaaaa cgattttgaa actaataacg aaatgttatc
     7201 aaatgaattt aaacaaaata ttaaattaac actgcaaccg tatcttgaac gactattcat
     7261 agatggttta tttatcacta tggaatttaa aaaaattact tcctataaag atgtacgacg
     7321 ttttttttat aaattaattg aaaatggact aatagtatac acttactcca accattacgg
     7381 atctggatta atactagccc ctatgtatat aacatcgaaa gaagaatgcc aagaaataat
     7441 taggataatt gaaagaacat atttggagtg gaatgaatga aaaaagcaat tgttactgga
     7501 gcaagtagtg aaattggcaa ggcaactata cttcgactta tagaagaagg atattacatt
     7561 ttagcttgtg atttagaagt aatgagagat aaattttatg ataatgaaat atcaagccag
     7621 caagaattga ttaaattcat tccattagac ttgaaaaaca cagacttaag gaatgcagtg
     7681 ataaaaaaca tatcaaataa tcaagtggat ttgtgtatta atattgctgg aaaaaatatt
     7741 ctcaaaagct tttatgaatg ggatgaagaa tctttaaaag atgtttttga tataaatttt
     7801 atatatacta ctttatttat caaagaggta gcagtgaaat ttatagagta taatactcca
     7861 ggtaaaataa ttcttatttc ttcccagcat ggaattgtag caaataagga gagaattcca
     7921 tattgcgtta gcaaaggaat gttagcgcaa ctaacacgtg cgttagctct ggagttagca
     7981 ccatattcta taagagttaa tagtgtttct ccaacatttg taaagacaaa agataacaag
     8041 aagttgctag aaacacctct tatgtattat gaagcacatg atcagattcc attgaaaaaa
     8101 tatgcagaag cttctgatgt agcatctgca atatgttttc tagctaatga cgagaataat
     8161 atgattacag gacacgattt agttgttgat ggtggctgga ctattcaata ggagtgaaaa
     8221 tttatgaaca aaagattttt aaaatttaga atcagaaata atatgactat agaacaagtt
     8281 tccaaagagt taaatgttag tgaaggggac gttctagcat gggagaaagg taagtattat
     8341 ccacctcttg atgtatccat gaagctatgc gaattataca atattagaat tgatgaactt
     8401 tgtgggacac aagaaaatgt taatcatcaa tataataata ttctaactat tttgatggag
     8461 aactggtgga aattactagc aatgttctcg gtattggctt atttaataaa tagtttaaat
     8521 aaaatatgag aaagttaggg gattaatatg actagtttag tggaagtaga atctttgtca
     8581 aaaaaatatg gtaaggaagt aattttagag gatataaatt ttactatcaa tcaaggagac
     8641 aaaattgctt taataggtaa aaatgggtca ggtaaaacta cattattaaa tatcataact
     8701 aaacttcaaa aagagacatc tggaaaagtt atctacaatt tgaatgaaaa aaatttttat
     8761 atgaattttg gtatccaaat gcaggatgga gtttttgatg agaggttaac aatccatgat
     8821 tattgtttat tacttgaaaa actttttgat gtggagggga aaacggataa atatttaaaa
     8881 gattttgaat tagaggataa aagaaaaaag aaaataaata cattatctgg aggagagaag
     8941 caaaaattta acattatatg tgcattactc catgatccag aaattttaat atttgatgaa
     9001 gtttctacag ggttagatac tattaacaga agtgttataa aaaaatatat aaaaaaattc
     9061 gctgagaaga agacactgat tttagtgagt cactatatgg aagaaattga gcaactttgt
     9121 gagagagtaa tttgtataaa taataaacat attattgtag atgaagatat tattgaaatt
     9181 agaaataaat atggcagtct agaaaaattt tatgtttcag aagttggagg acagtaggat
     9241 gaataaatta aaaggactat ttaacttaga attaaaaaaa acaattcgaa caccaatcat
     9301 tatgttcttt tcaatactag ccccacaatt ttttatttat attcaatctt ctttaagtga
     9361 agaagtaatt atgaatggtc agagcatacc ttctattgac tatagtttcc ctatgtttct
     9421 ttacttagcc gttatagtag ttggaatagg taacgttggt gtaggaatgt catataatag
     9481 attaattaaa ttctttactc gattgaaagt ttccaacgtc agagctatag attttatagt
     9541 agctaacttt tttgtgcaat tatcgattgc tgtattgtca accttactat tgtttctttc
     9601 atccatacta gttttagata tgtcgttaga aggtagaaac tggacaatat ttttccttgt
     9661 tttcttttta gtatggataa tgacatattt aataggtatc gtgttggcaa atattgttaa
     9721 agatgcaaaa acctctcaat cagtgtcatt aattgtatat ttctttttaa ttttctttag
     9781 tggagtaacg tatcctattg agttaatgcc agaactgtta caaaaaatta gtaaactatt
     9841 acctacgtac tatggattac gtatattaca agaagcatgg tatataaatg ggaatattga
     9901 tacaacacat ttaattattg ttataggatc cactgtaata ctatttgtga tctccctgaa
     9961 aatttttaaa tttgattaat aatagtaagg agcatgattt atggatgtta atccgattat
    10021 tcttgaaaga gagagctctt tttctaataa atggttatca ttgttttcct ttaacgaagt
    10081 aattgaatat tttgacgaaa tagagagcat agaagtaaaa atggaatctt taaaggagga
    10141 aattataaat gatttagaag acttaatagg ggaaacttca ggggacatta aattaacatt
    10201 gattaatctg aagagaaatc tctataataa tagaaaaatt aaactgcctg aaaacactac
    10261 ctcattagac agtcatgaag cttggagtaa tataaaaagg gaaataaaaa aacttgctta
    10321 ttttaggaat aaatctaaag tgaaacgtga agaattagat agtgtcctaa aagagaactt
    10381 tattaaagaa agaagaagtt tatggaaaga ggcaaaaagt aatatttgga tgaaaaatgc
    10441 tttaaatttt ttatcaccaa attcaataat aagcctaaag aattatcttg aaaccaatgt
    10501 tgatgaacac cgttcaaaag aaaaaaagct agattatcta cttttaaaag tacttactag
    10561 agcttcaaca aagaccagtc cgtttagtac attaacccgt aactgtataa caattagaga
    10621 tatagaaaag gagcagttta ataaggttga atataaagag acagaaaaaa tatatacaca
    10681 agtaaattat aagttgttac ttgaatatta tgaagaatta aaatacagag acatatactt
    10741 taaaggcttg tctttcttta ttaatgatac gacattagtc tttgataata ttttgtatgt
    10801 aacttcttta gtgaatcata aagacaagcc aaaagtgttc gaaacaacag atcttctaca
    10861 aaaatttaag ataaacaatt ttttgagtga tttaatagat atttttaaga caaatagctc
    10921 agaattttta acttatcaag aaatttttga tgaattggaa actaagggtc ataaaaatat
    10981 acactcatca ttaaagttct ttgctaaaaa gaaagtaatt cttacgaaag aaaatctaaa
    11041 agaagagtat aacataatag ataatctact ggagttaata agcccttgtc aggaagataa
    11101 acttataaat aatgttgtaa tgatgctgaa ggaagtaaaa gaaagaatta gaaaaattaa
    11161 tgaaattcct tttaattcag atgaagaaat atatctagtt agaaaaaaat taaaagaaat
    11221 aaataaatta ttgaatattg atcccatacc acaaaaaaac tttcttgtac aggattattt
    11281 tttaaatcaa ttaaaagaat ccatcaacct ttctgaacgg caagtacaga ctttaaagaa
    11341 aattttatat ttaataaaaa tttttgatgg tgaattatat ttacaattat taattgggga
    11401 ctggatttct aaaaagtacg gtactgattt tattagcatt aaagaaaatg taaatgttat
    11461 aaaggaaatc gtgaatatta ttatccaaaa tgtagataat atatcaaatt taaatttatc
    11521 acctctcaac ttaaattcag aaatattatt tttgactaaa ctatcggaag tgagaaatca
    11581 atttattgaa atgataataa gtagtgatga tagaaaaact ataaacatat ccgaagatat
    11641 tttagataat atgataagta atatggattt tctcaaggaa tacgatagtt ctaacagctt
    11701 tttctttcag gttaataaag ataaaaaact ggttattaat aacatttata ctggatatct
    11761 ttcctatttt aataggtttc tatacttcta tcctgaggtt atggatattc ctacagtaaa
    11821 gagttatttg aattttttaa atgaagaaaa aagaatcgcg gatattttta atatttatgg
    11881 atttaacgca aatataagac ctaatattac tgaaaaagtt attcaaatac caaataaaac
    11941 agtaaatttt gacaaagaaa atcagaagtg tatacaaatg gatgaattga ctttaaaaat
    12001 agatgaagaa ctagggatat tgaaatttta tgaagataaa aacaaaaagg aaattaagcc
    12061 tatctttatg ggatcagtta taaaatctgc tatcccttca atagcagcta ctttagatac
    12121 gctttctaat aatggctctc ttcaattaag tttatcaaaa caaattatta actatcatat
    12181 tctaaaagat gatttttttg aaaagaagat tccagaagta acagttagtg atacggtcat
    12241 tttatctcgt gaaaagtata tatttaaatt tgaagtcttt aaaaatgcaa gaaaattgga
    12301 ggatatagaa aaattaaaat ggttagtcca attttttaga gataaaggaa tgggacaagc
    12361 tttctttgtc agtaaagcta ctatcaaaga gagttcagaa agaaagtatg tagagattga
    12421 aaaaccacaa tattataatt ttacgagtat atctttttgc agattatttt ttagggaaaa
    12481 taagagtagt gattatgttg tttttgaaaa gtgcaatcct gaaataaagg aaaacacagt
    12541 gacggagtat ctagctgaaa taacaaatta aagaaaatag gttttactga ggagggagct
    12601 tatgatatat agaataagag tattttgctt tgatattaaa tatcgtcaaa atcttgttct
    12661 agaaagttta gattacgtga aagaaaagaa tattaagttg atatctataa agaaaaggtg
    12721 ggaaaacggc tttcacattg aatatatatt agaaagtaga tttctgaaag aacttaaagg
    12781 ttatttatat gatcaactta ccaatattcc tgatattcca aaaaaagtat ttgataaaat
    12841 gcttcatcaa attagattat taaaagacat tgaaaatgcc cccgcagaaa gcaaaaaagt
    12901 gaaagaaaac aaacaaatag taattgaaag tgtaggtact aatttatcaa atatatacga
    12961 taatgagagt tatttagaaa ttcaaaagat taaacaaaat tggataaaag attttacagg
    13021 agaaattttt gaaagtaata aagagcagaa aaatagtatt ctcttaaaaa tgatgttaat
    13081 tgcagcaaat aaatttcatt ttgatgatga ttataagggg tttaaatttg gtgttttatc
    13141 ttattattca cattatcaag gttacattaa tcatattgaa caatttcctc cactttacaa
    13201 acaaaaatat aaagacatga tttttcatgg agtgtcaacc actaagaaat cactaaaaga
    13261 tctggacgat tggttaactg agttaagtaa acagagttta aatgaagata tattaattaa
    13321 ttggagtaaa atgctagatc agttaatgga aaagcataga gatttggttg ataagaaaaa
    13381 gatatatagt ggcaatgatt atgagataga acagtaccta gataagatga ataatgtaag
    13441 taattttcat aaaaagttta cactgaataa aaattttaaa tggtttattt caagtaaaga
    13501 atttaaagtt tatagaggta ctatcaatca aatgtatgaa gtgttaacct ttttatcaat
    13561 aagttcactt caaaggacaa tttattgtgg aggaataagt gaatatatat ttgagagtta
    13621 taaatttgat attgatgaat tattaaaaga tatcaacgaa aagtatggct attaagtgag
    13681 aggtgtatat atgaagggtg tttatttttt tttatctgaa aatgacacaa taatttttag
    13741 aagtttaaaa acaaaagtta aaataaggga tcaaaaattg tatagctatt ttttgggaaa
    13801 atacttgatt aaacctaagg agataaattt tataaaaaaa aatgaaattc cgcctacttt
    13861 attatcagta ttaggtttca aagaggaaga tctaaataag aagactcaga ataatactaa
    13921 taatagcaca gagatttaca gaaaaattat tgataaatcg aagtatccac ttaataaaat
    13981 tgatgaaaaa ctaattgaat atatagattt agaaaaactt ggaattcaaa attgcacgat
    14041 aaatcttata aaaggtgaaa aagtaattaa tattaatgtt gatgaatatt tgagaaaact
    14101 ttctttagat agcggtgaag accacattag acttgattgg aaccatttga attggaatga
    14161 aaaagtgaaa atttcaaatg aatgtgtcaa ccagaaaaaa gagttatctc atttatatag
    14221 tgaaataaca tattctaagt ctccccagta taatgaagct tatttattca aggaggaccc
    14281 taagcaatcc atgatttttg tcggagaaga cattttggag gtaacacaat caataattac
    14341 ttacctagta aataaaaata cgaaattaat ctgtgctaat agtaggaagc aggcagaaaa
    14401 atttttgaga aagaaccaat tatctgttca aaagcaaaag atgaaacgat atacagaaat
    14461 tttagagggg tttgatgtat ataaatatct acatcaagat tctcatgaat actatttaga
    14521 aatgtttttt ggagtaaata aagtatattc cgagttattt aatgatttag atgatttaaa
    14581 tacgagaaaa agcaaagtta tagatctgat acggaatcaa ttacagatac aacagcccaa
    14641 taaattgaaa atcatttgga attatgatgt atttaataga aatgtctata agaataattg
    14701 ggaagttttt agcaacgaca aactaaaaaa actcaattta aaattatata atgaaaggac
    14761 tataagtaat tgaagaatat atatataatt tcaaacgaca gtcattttca aaaaatgttt
    14821 ttaaaaagta ctaataatat agttactcct attaatataa aagaagtaaa aaggatagaa
    14881 aaagaaagta tagtattaca tttaagcgat ttcaatacat tgtctttaga taaagtaata
    14941 gcgaataatc tcaatggaaa gctattctta agggcgaata taatatttga tcaagtgttt
    15001 attgggccat tatctaatca aaattctgcc tgtttagaat gtttggaact ttacaataaa
    15061 aataataata aggaatcaga ttttttatta tttaaagata ttaaaacgcc aattgatcat
    15121 caaaatataa gttatcgaaa gataactgaa ctgattgatt tgatcattga aggttgggaa
    15181 agttttttaa atcaacttat tattctatct ccaaagatta ccaaaagaat ttctttagtc
    15241 caacattatc aatgcactac ctgtagccat ttaaagtcta atagtgctat taacgcaaaa
    15301 gtaaaatata gtaataataa aaaaaaatca aaagatatat atagaactaa agaaaagttt
    15361 aatgtaaata atttttataa atttactgat aaaaactttg ggttctttca tcatcaatac
    15421 agagagtata tttcaaacta tgccccttta aactgtgttg aagtaaatgt agatgatagt
    15481 tatgaagctg gatggggtag gacatacaca gtatatgaat ctactgtgtc agcttatttg
    15541 gaagctttag agcgttatgc taattcatac aatagaagat ataatcggtt attaaccaaa
    15601 agttatgaag aaattaaaag tatcgcagtt gatcctaaaa tatttacttt acacaatgac
    15661 gaatatagag ataatagtta taaattcaat aattatactg aaaagctaga aattgattgg
    15721 atatatggac aaaatttgat aaccaaagag caagttttaa ttccatctca aatggttttt
    15781 tatcgtgatc ttacaaagaa agatagagaa aaaagattcg tttatgaaac atctaatggg
    15841 tgtgctttag gatctagctc ggaagaagca atattttacg gaatattaga gattattgaa
    15901 agggacagtt tccttacatc atggtatcta aaagaaaaag ttactagaat aagtgaaaat
    15961 agtttgccca aaaggataca agaaattata aaaaaattaa atgaaaacaa acaaaatttg
    16021 tatttgtatg atattacgaa agagttagga attccagttg tatgggcact ctttattgat
    16081 gagaacaaaa atgctaaagt taaaactttt tcagcagctg gttgccatct agatccatat
    16141 aaagcaattg aagcagcagt ttttgaagtt attacctctg ttcctacatt tgtacgaagt
    16201 ttagacaatc aagaaataaa agaaaaaatg gaaatgatgc aaactgatta ttctttgata
    16261 caagatattg atgatcatat aatttatcat gcttatgatg agtaccaatc aaagttagag
    16321 tttttattaa atgataatcc tattatggat atagaggaaa tttataaaaa ggatataaag
    16381 gaaaaattta accaggaaat gcttacttta gatctaaaga tcttactaga cctagtaaaa
    16441 accaattata gtgacgtttt tgctgtaaat ttaacagata aggtattaca aaactttgaa
    16501 ttagaggcat acaaagtttt aattccagga ttattaaaca tgtcatttgg acatagtcat
    16561 aggagagtta atataaatag gttgaagaaa tatgggagaa aaataggaat tgatccagat
    16621 aatattactc ttgaaacaat taatcaaatt cctcatccgt ttccctaaaa atagtaaaga
    16681 actaatttct agaaaataaa ggttgtgaac tcatgagtaa aattgaaaaa gagtatatta
    16741 acgattgggt atctttacat ttttattatt atgatcaata taagtatgat caattaatat
    16801 taaaattatt agaatttttg aaatctgaga aaaataactt aaaaattaca caatattttt
    16861 tcatacgtta ttgggagggt ggtcctcaca tacgattaag atataaaaca gtgaattcta
    16921 atgagtaccg agaagaagtt tttcgtaaat taaaagaaat agcagatgat ttttggaaga
    16981 atcatcctac tacagtaata ctaaatgaaa gtgactatca aaaggtaatt aaagaagtac
    17041 ctgatagtaa tacggaatct ttggaatact taataccatc tgaaacaata aaacctatta
    17101 aatatgatcc tgagtttgaa aggtatggta ataatagatt aatgattaaa aatgaatctt
    17161 tttttgaaat tagtagtgac atcagtgtgc tccttttgaa atttctttta aataaagatt
    17221 catcatattt ccataaattg attgtaacaa cagcaacctt gaaattgtta attgaaataa
    17281 cattagccag gtatactagt gaaacgaaag atattttaaa ccacatgatt gattactggc
    17341 aaaataataa tatttttctc gataaaacta tcgtatctca tcttatgcaa catcagaatc
    17401 aaattgacaa attttgtaaa tttttaaaaa aatatgctaa agaagaaatg attaaaattc
    17461 aaaaaattaa tgaggaaatt tactctcttt ctagtgaaga tgatttttat tatggagtta
    17521 ttagttctca atttcatatg ttagctaatc gattgggcat ttttccaaaa tatgaaatag
    17581 tttgtttaga agtcttaaaa actttcattt aggaggttat tatgggagat tatttttttg
    17641 atattaatga atttaataga atgagaaaaa gtatggaaac tccatctttc ttatggggga
    17701 aaacaaaacc tagaaatgat tttttttata aagataataa ttctaaaact gatattagtt
    17761 ttgatgttgt ggactcaccc ttaccgtctc taagtttaga agaagcactg ataaacagaa
    17821 aatcaagttt gctaaatacc tttactggta acatgtcaaa gaatgaagtg ctcaagtatt
    17881 taaatagtgc atttaatact acaggtaaaa aattaatagg agataatacc gaaatcaaaa
    17941 ggaagccata tcctactgct ggtgggctaa atactataca gccttatgtc tttatcaata
    18001 acgttgatgg cttaagtact ggattatacc aagttaatga aaacggtata acatacaaaa
    18061 aaaggatatc atatttagat ctcgaaacaa tctcaccgtt aacatttttt aaaaatgatt
    18121 ctagaaataa tacatttaag aatgtcaatt taattgttat attaattgca aagtataata
    18181 acatattttc taagtatggt tttttatcat ataaactgct ttacctcgaa gctggacata
    18241 ttgctcaaaa cttacaatta ctatcctctg ttatgaatct tagaagtctt ccattaggag
    18301 gatgttttaa tgataaaata gaaaaaatcg taccagaaac tgaatttgaa tatctgtatt
    18361 ctatggcggt gggataatga aatactatta tttagatcca atatatataa taaaaataga
    18421 tcaagataat attcttaatt tctataattt agaaactaag aatattaatt taagactacg
    18481 tggctcaaat aaaataaatg aaagtacatt gtataaggtt cctgaacata ttttaaaaga
    18541 acgtttctct aacaactata gaaagttcta ttatgattat gagcaatatg agtataaaaa
    18601 agaaatattt aattttttat ctgggaataa ttcaatcgag tactattcct ccattcaatc
    18661 agaaattgat caatgttttt tccactttga agctataaat aaacgtgacc atcatttctt
    18721 gtcacaatta aatataaata gtaaaagaga atacaaaatg aatattatgc cgtttgaatc
    18781 tgataaagaa aaaaatgatg aagaggataa gattaatttc tattatgaaa aaatagatga
    18841 gatagaattt tctttagggc caatagtgtt cggaagaaat tacatgaaag tttctcagaa
    18901 agacattaaa tatagtagcc tatatcccac atttgaagag aatttgaaaa ctgaaatact
    18961 aaatttcttt ctagataaag tgaataccta tgaaactagt tattccaatt gtttatacca
    19021 acaaaacaga tttgggaaag gtgtagttta caaagaagaa tactttagac cattttagta
    19081 ttataaataa aatgacacat tactaaataa agtctaatgt gtcatttttt attgtgcgcc
    19141 cggcatgggc gacaacttgg tggtgaaagt ccactataag cctttacagt aggaattatt
    19201 agccaaaggc aagggtgtcc atcgtgaggt ggaatctgaa ggaagccaga ggcaaacacc
    19261 tgcactgacg aacagaaatc tcataaagaa ggccggatag gtgtgggtaa gcttgcaata
    19321 caaagtgaag tccaatactg tacaagcacc gtcaggtaaa tgaggcagtg acatgggtgg
    19381 aaggttgtcg ctcttacccg gggaggtctg tctagcgggg aaccgtagca atagcgaata
    19441 ggcggaagtc agccgatgtc atagtagtgt cgattgggca tgaagaacag gacaatatca
    19501 atacaaagta aagattggag gttaggagtt gcgattacaa caaaaaacag tgagagttgg
    19561 caatccaatg agtcaagtag gtggaactga aaacgacaaa agatggatgt gttgagtata
    19621 ctcctagttg gtggtgtata agtaataaaa aaataagaaa ataaattaat ttaaaataaa
    19681 attgacaaac aattattgat agtttatgat agatttagaa atatagttct aaaaaatgta
    19741 cgagtaaaag tatacagtag attaagttta attagtttga agccgatact agttatcttc
    19801 aataaattaa ctggaaagtc gtggatttta ggtaatgtta tgaaagtagg aggggtgttg
    19861 tgaaattgaa aaagaaagca ccaaaaatga aaaaagtgaa tttttcagta atgtatagaa
    19921 aacatgttac aaaaaggaga acaatagaat gatcattctt gaggatgtca ataaacaata
    19981 tacaatcaag tccggtttta ttcataaaaa tatccaaacg gtagatgcat taaaacatat
    20041 taacttaacg atcgataaag gcgaaacaat cgggttaatt ggcctaaatg gtgccggtaa
    20101 gtcaacacta ttgaaattaa tattgggtat tttaacgccc aatgatggtt cggtgaagct
    20161 ctttggaaag acgccagtgg atcatcggaa attacttatg aaagatgtcg gagtggtctt
    20221 tggacaaaga ccccaattaa gatgggatgt ctcaccgaaa gatgcctatg atttaaataa
    20281 ggaaatctac aaaattgata cagaacaata ccagaaaaac ttacattact atgctgataa
    20341 attgcgggtg agagattttt gggatcggcc tgtgcggaca ttgagtttag gacaaaaaat
    20401 gcgggcagat ctattggcgg cgctactcca caatccatcc ttattgattt tggatgagcc
    20461 cacgattggg atggatgtag tcagtagaaa tgtcatgtta gaattaataa aagaattaaa
    20521 acaacaagtc accatcctat ttacctcgca taatttatca gatgtgtacg aattatgtga
    20581 tcgatttgtt attttaaatc atgggcaagt tgtcattgat gagaaaaaat cagtcattag
    20641 tcagcggatc ggttttgtgt ctattcaggt cactattgcg gaaagtactt taaattttga
    20701 acccgcaaac ttttctatta caaaagcaaa tgattatgaa tataggattg aagatatccc
    20761 taaagaacag ctgaaagaag tgctaaatga cttgtatgaa cgtaacacga tagaagaatt
    20821 atctattcaa aacaataatt tggaggcgat actgaatcaa ttagaaggag cgaatgtatg
    20881 aagcagttaa tcaaaatagg catcaaaaaa attacgaatt atacggacta cttaactatt
    20941 ttgctgctta aaaatataat ttatttactt gttcagtggg cattgtggac aactatttta
    21001 aggtatgatg atagtttagg gagtattcac tcaataatga gttatttttt gatcgttcaa
    21061 ggattagaca ccctctatcc gtatacaagc atggatgtta gtgatgatat taaaagtggc
    21121 gatattatta ataagttatg taagccggtc tcgctggttc aacaatattt ttatgaagca
    21181 ttcgggtcat ctatcaccaa gttttgtaca gtagtagggg ttaattttat tgcgctaatc
    21241 ttttttgccc aatctatatc gggcactaaa ttattaggtc tattcctctt aataattgcc
    21301 ggatacctgc ttaatttttc aatcgaatta ctatttggct cgattgcttt ttttacacag
    21361 agtatttggg gcattgagtc attaaagtct gcggttaaag tgatctttgc cggcagtatt
    21421 gttccgattt attattaccc gaagtggtta gttcagattg caaatttact tcccttttcc
    21481 tacacacaag ggaatatcgc tgcctacttt aatggagaac gtacattgtt ttcggtatta
    21541 gggattcaag tgatttatgt ggtggtattt atgttaggag ctcagatgat tttgcgatat
    21601 gggctacgtc agttatcaat taacggagga tagagatgtc tgttattaaa gattatacac
    21661 gtttattttt ttgcatgctt cgtatcaata ttaagggctt gaagtcatat ggacaagatt
    21721 ttttcgttgg tattattgcg atgattataa aaaatatagc caatatcatc ggagtattta
    21781 tgatttatga gattattccg gtcattaatg ggtggtcctt accagagtta ttatttttat
    21841 atgccttctc aaccattagt ttttcatttt ggcgctgtct ctttatgaat acattaaatg
    21901 tgtcgtacta tgtgaggaat ggtgaactgg attctttttt aattaaaccc attgatccgt
    21961 tgtttcaaat atttatggaa gggttcgatg atgatgcttg gggcgacttg ctagtaggat
    22021 ttattgtatg catgatggcg atggcacaat tgcaactgcc atggtgggtc ttcttacttg
    22081 tggttattac cggtctgttt tcgagtttaa tctttgccag cttttctata atgggttcgc
    22141 ttttatcgct taaagttgcc cgcgatagtg atttatccga tatgccgtac attgtgtttg
    22201 acttaattag atatccaatt tcaatttacg gccaagtgat gtacaacgta tttgtgttct
    22261 ttttccccat cgcctggatt agttacttac cggccaaagc cttattaacc gatcatagtc
    22321 aaggtgtttt atattcaggt ataagtatag ggatatcatt ggggctcttt gtcttgtgtt
    22381 atgtcatatg gtcttcttac ttaaagcatt atcgcagtac gggaacatag ttaaagtata
    22441 atacgagcca aacctttaat ctaagaaata tccattttac taaattaaac ctaaatctta
    22501 ctgacaagta agtcggtagg tggtcctatg ttagtgtggg aatgatgaag agggatagaa
    22561 gtttccaaaa tttacttcta ttcttaaata ttttaaggta taaatctgtt cctgctaaat
    22621 tatcttaatg ctataaaaag agtaggttaa ctagtctact ctttttatga gcagaatttt
    22681 ttctgttgaa ccagtacgtc agtaagcgcc catgatttag gcgactagtt ccaccacaaa
    22741 caatcctcta aaatagttaa tgtaaagtaa aaactattga gaggattttt tgtatgtcaa
    22801 aatcaaaaat tatcaaagta acacagccaa agactcactc caaaaaactt aaccccactc
    22861 aaattatgag tatcatttac acggttaatg taagggttat cacttaacga aattaatgat
    22921 catctgaaga attgatggcg tataataagt taatgatttc gtcaagaaca tcagagaatt
    22981 cgatatctgt tgtatagcta tattttttag aataattttg ccactgttga ttttgaatgg
    23041 cgtcagtctt aaatttattt agtaactcga tgattttatt gtaattaagt tcagtgccac
    23101 gagcagaaaa tgtttttgtg caggctgttt gcaattgaga aaaatcaatt gcatctttct
    23161 ttaattttac aagaatataa atatcataaa aatctttact gcgactattc aaaaaacttc
    23221 tagaataaat agtttgtagt ttttcagcaa gaatagtttc gatcgtataa gcagtgattg
    23281 ggaaattttc atcatcaaaa atagctttgt aatcataagt gatcggatga ggagtcacaa
    23341 tatcaccagt tgcaatgtct aggtgtatgg tttgttttat attttcaagc tgacagagaa
    23401 tagatactcg atagccaccg tgcattgaca ccaataacat tggagagtaa aaatccgcct
    23461 ttgaaaatgt aatgttttga ataagggcta cgacttaatt ttttttaaat aacctcaaga
    23521 aaataataag tcataacaga gttgaaagtt aagcctgttt gttttgagat tttgtggcag
    23581 agtgctgtta acttcgcttt gttcatatga gcacctccag tgttcgttta gtctctttta
    23641 taatatgcat ttctgtagcg tatttataga gttttgctgt gttcttctta ggataatctg
    23701 cataaagttg aagtgttttg acaaaaagtt cagagtcgat tttttctcga ttgatgataa
    23761 aatcacacag agtacgttca agatcgtaaa cttgtacagt attgcccata ggagtttcta
    23821 cgcttgttat tccgagagaa ctatattctt tagacacaaa atggatattt agatttgatg
    23881 gtggatcatt aaatcggtag cctcttgcga cagtgacttc aaaatattgt ggaatttcat
    23941 cagtcaggcc ttgaagataa agagcagaaa tataggaaaa gatagccttg gaaaagcgat
    24001 attgaaagaa ataatattca tcgtaatcac cattaggggt caggtaaatg ccttgttcaa
    24061 cgcggaaaat tgtccccttc ttctctagtc ttgtcaggta tactgtcgga atatcgagtt
    24121 tctgacaatc ttggtgtgtt atgatcccat tattttcttc tagataacgg agtagctttt
    24181 gctttttagt tatagtcata gatgtccctc ccatgttgta tttacactac gattatatat
    24241 tatttatagt gtgggtacaa catttttcat atgtaacaat gtaatacata atattaattt
    24301 ggatgaacta aaaaaattat tacttaaata taaaaatatt cttactaaat taaacggaga
    24361 tgttactgac atgggaagtg acgggtggta ttatgttagt gtgggaatga aagagagatg
    24421 gggtcctcca attagccctt atttctttta ggttaatgta aattgcccta tttgctatgt
    24481 ttatcatttt aatgctgtaa aaaagtggac tgagaggtct gcttttttgt taggatgaaa
    24541 cattttttcg gaataatgta tgggccatta cgtaattttg cgtgatggtt tttgttatgc
    24601 gtatgattag gaggtgatta tgttgttatg aagcgacagg agatggtgca ggcttatttg
    24661 cggtgttcgg agtgtggatt actgatgatt atcccacgac gggctgctcg gaagaagaag
    24721 gttgggcatg ttaaacatat gtactgtagt cagtgcaaat gtaagcgagc gtttattgaa
    24781 gaagatggat attatcagta tgatccgaaa gaatttatca ataagcgggt tgagattaaa
    24841 taaagtggat tatctctagt taaattcagt atgatgagtg tattggcaca agaaatagaa
    24901 gatagagagt agggagtctt agaggctcct cttttttata aagaaaacaa acggaatggg
    24961 gtgattaaag tggtaaaaag tattgtgaag aagcatgagg caatccttga ggcaaaaggg
    25021 attgatccag atgattggca tgaagagacg ttcaagtcag tgatggcaga aatgacttat
    25081 cgcccgacta aacatcaacg caaccaattg attgaattca aacgaaaaga agaaatagaa
    25141 gaatttgaag aagagatgat tgagttgctg aaagagaaaa ctgaacgaga agaaaaaata
    25201 ccttcttctg agaaacaaaa ttctttaata aattcaaatt ctgatgaacc tgaagggggt
    25261 gagcaataaa tttggtaatc tgacagagat ggtgtgtgag tgagagtaac atataaacaa
    25321 taaataaaag gagtgggaat aaaaaatgga agatatgttt tcgaatttgc aacaatttat
    25381 tactaatttt atacagcaag tacaaggtct atcgccatgg cttgcagcag ggtgtgcagt
    25441 aattgtggcg ttgatgtatg cttttggtgg tcagcaagca tcacaaatgg cgaagagttg
    25501 gggctggaag attgtggtcg gcctgttcgt tatttggggt gtagcagcaa tcatcaatac
    25561 attaattagt atgttcggtg cagatggtag tgttagtgag attgacatct caagtttaga
    25621 ggtgattaaa gacacagtag aaacgctagg agtcggtcaa actgtcgcaa tggcctttat
    25681 cggtttactg tagtcgatag atagtcgtat agatgagatt gagctagggg gcgactccta
    25741 gctttatcta tacataatag agatggaggt taatttatga gtctgaaaga ttttttcaca
    25801 aatatattta gtaaaaaaga aaaagaagag gctgatgagt tagaacaacg atcaagctgt
    25861 gagacaaaag cagacgattt tgaagaaatt cgctcagata attcttcaaa ttacgtatta
    25921 aatgatacgg atgggaatga tgaaaagtcg gatcaacaaa aagacaatca aaacggttca
    25981 gatgatgaga atgcaccact tgataatgaa gaagccgtaa acaacgcttt taaagatgat
    26041 tcaaagcaaa aaggatcaaa taaagaaggt gatgaacatg aagatagtga aaagttagtt
    26101 gatgaaattg atcagcagga ggagcagaat aagaaacaag tggctgaaaa taacgatgaa
    26161 gagaagaagt ggcaggaacg ttcatggagt caagaagtgg ttgataatga agctgatgaa
    26221 gcagccaccc tgaagcagga acaggtaagc gaggagaagc atgttcaatt tattaacgtt
    26281 gaagcctata aagatttatc gaggttatca gatatgattg aacggcacaa acataaagta
    26341 ggtaatgaag ccttgctaag ccgattaagt cttatagaag attcagctga cttttcaaca
    26401 ttggatgaat ataagcgaga ctacgcacta aagcatattc agtcgagcga tattcaagac
    26461 attacgcaga catttgttga taatctagat tcattaattg aaacaacaca attgaactta
    26521 gtgacaaaac acgatgaggt gttaacaacc aattatgagc ttagggcgtt agacgctatt
    26581 gagtttgagt tagatgatct tcaagataat aaggatcaag cgattagtca gtataaggaa
    26641 aaacaaaata gtcggtatga taaaaagatt gaaacgttta agaaaaaaca ggaaaaagaa
    26701 cttgaagcct ttaaacggaa gcaagaaaca aaatttttag agacgaaaga agaattaatt
    26761 aatagacgcg ataacaatat tgaactctat gaaaaggaaa aagagaaaga gtataaccgc
    26821 aaatacaaag cgaagttgaa taaacaacgt tacactgaag aacagttagg agcgaaagag
    26881 cttaacccaa tcaaacaaga tgttttacaa gaatttcagt ctgaattaaa agaagcttcc
    26941 aacaaagttc aagagaaact aaaaccaaag ttaaatgaaa ttcgagaagg cattaatcag
    27001 aaagaacacg actggattca agagattact gaacagaagc gcttatcaga agaacgaaag
    27061 aaacgtcgca ttgaagaaga gagattagcg ttacagaagg aagaatttga gctggaacgg
    27121 aaagagcgat tagagaagtt ggagatggcc aaagaggcac aacgcttaca agcattagaa
    27181 cggtctgatg atcatcagaa agaaattgaa cgtctgcaga gagaacttga gaaacacgag
    27241 aaatcaactg ctcaaatgaa tgaggtatta ctagctaaat taattaatca gcttgatggt
    27301 gagcaggaag ctgataaaga tttgaaaagt gacgattcaa taaaaaagcc tgaagtgaag
    27361 ccagataact attaccgcaa attttattgg attgtatcct taattgttct tattctggta
    27421 ggcctcgccc tctggttctt tgtgttaaac gatagcagat taccttctag taaatcatca
    27481 aatgtttcag atgtagcagt tgtagaaaca gcaaagcaag ctggtgaaga agctgaacat
    27541 gatgagtctg attatattcg ccgtggatct gatgataatg taatcactga cgaacatgag
    27601 gatatagagg acaaagcgga cgatatacca tcagctgaag tagaaagtga agaagagaca
    27661 gctgagcaag cgactagaga agaattaaaa gagaaagttc agattctaga gaaagaattg
    27721 gagcggtgga cttcggttga taatatgaac ggtgaaccga ttagttttga tgaagcatta
    27781 gaacgtggag attttcaagc ggcgattaag acgattgatt tagatgatga tgagtcgttt
    27841 aatcggctaa cggatgaaat gcgtcgtcaa ggcgagctag aggtgcttca agtatttaat
    27901 gaacggtatg atacgactta tggattgatg gatcagcatt atctatcgga caatatttgg
    27961 ggagtatgga acgagatgat gtggttaact aatgatgaac gagtgcatat gggtgatcac
    28021 cgcaagcaag atgtcgccaa ttatctatgg gataatcatt tctattatta tagtcgttgg
    28081 ttaattaatg cccattagaa gttgaaagaa gtggagagcg agtcagtggt cgcccaatac
    28141 gacttatcgt attcaatgtc gtttgagcaa gagacttttg aagatttatt ttgaaatgaa
    28201 aggagaatga gacggtggat aaattgaaaa gatggtggcg acaactaacg tcaaataaca
    28261 gtggacaatc tggattagct catacccatc attattcggt tgatggagaa aatttaccgg
    28321 atcgttctaa cgggaacaaa aaacagttgt atcttacgat tggtctggtc gccatat
//
