LOCUS       NZ_CP040417            22643 bp    DNA     circular CON 23-APR-2024
DEFINITION  Dolosigranulum pigrum strain KPL3077 chromosome.
ACCESSION   NZ_CP040417
VERSION     NZ_CP040417.1
KEYWORDS    RefSeq.
SOURCE      Dolosigranulum pigrum
  ORGANISM  Dolosigranulum pigrum
            Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
            Dolosigranulum.
REFERENCE   1  (bases 1 to 1957024)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Eslami,S.M., Gao,W., Bomar,L., Fernandez Escapa,I., Roberts,R.J.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     The nasal commensal Dolosigranulum pigrum exhibits stable synteny
            and highly similar strain circulation over a 20-year span
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1957024)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2019) Microbiology, Forsyth Institute, 245 First
            Street, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-AUG-2018
            Assembly Method                   :: HGAP v. 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 351x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017655765.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 02:25:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,875
            CDSs (total)                      :: 1,806
            Genes (coding)                    :: 1,779
            CDSs (with protein)               :: 1,779
            Genes (RNA)                       :: 69
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 27
            CDSs (without protein)            :: 27
            Pseudo Genes (ambiguous residues) :: 0 of 27
            Pseudo Genes (frameshifted)       :: 12 of 27
            Pseudo Genes (incomplete)         :: 15 of 27
            Pseudo Genes (internal stop)      :: 6 of 27
            Pseudo Genes (multiple problems)  :: 6 of 27
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:08:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1124429
            Orig. end                         :: 1147072
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040417.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
FEATURES             Location/Qualifiers
     region          1..22643
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="4"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22643
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22643
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12643](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12643)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(998..1540)
                     /locus_tag="FE328_RS05275"
                     /old_locus_tag="FE328_05225"
     CDS             complement(998..1540)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004637030.1"
                     /locus_tag="FE328_RS05275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05225"
                     /product="NYN domain-containing protein"
                     /protein_id="WP_112788080.1"
                     /transl_table=11
                     /translation="MKREILYVDGYNMIGAWPNLKRLQQRDEIGTARDELLHELSNYGA
                     FAGIEVIVVFDAQLVPGITQRYEQYDLEVIFTQEGETADEYIERSVGEENFLVSNVKVA
                     TSDLAEQWMIFQRGATRKSANELWKDIKQTKQSITSEATAYRLSQYRRNSPITDEDQYR
                     LRKLYHQMVNQKTDKTE"
     gene            1637..3541
                     /locus_tag="FE328_RS05280"
                     /old_locus_tag="FE328_05230"
     CDS             1637..3541
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="FE328_RS05280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05230"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_112788081.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.2e-36, bitscore:
                     122.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKCRSALSRIFSFCCLLIITIALFRPASEPVHAAEDVQLIVEY
                     DHVDNMPNEDQLPPQVTQVHTSRYTPTRALTIPRQYIHLLRSQAHIKSIRSNQTVVPLE
                     ADATERTPTSANYPWNLQTIGADIAHQQGITGKGVNIAVVDTGFYIDHPNITFAGGASI
                     FNDDPWTNDHMGHGTHVAGIIAAAADSEFPGVAPDVNLYGVKVYHKDVLDADNTPSTTV
                     YNLTEGIYAAMRQGVDIIVVSSGFQGEDEGMRQAVQQATDQGIVIYSASGNGQPAVDYP
                     AAYPDVISVTSIDQFQHAASDIIAGPENDLTAPGVEITSLSSPDSVYGYPFATLSGSSQ
                     ATPHAAGITALLMQKYQITASEATERLLEQAQDLDDADFFGHGLVQFLAPEDRKPTNNI
                     DRNSSHTDAATKEPSELYWAEPTAQGTRSFLADEYFAQVQAQGILALTYTDTGLDTLRL
                     NEAQVRTMKSRQITLRFYLNDIEWEVPADALDTGEALFKFTDVTTHDAIETASAQSTVI
                     KFEIQQNGAPKTTFTQPMTYRFLAQDNWEDSTDIYILDNEQNWTALDAEHSGHYLQRTT
                     NQTGTFAVFNTKDINNTTPAQSNPNSPTRTLWIIVGISTLVLAGLIIIMKHWINPRQQ"
     gene            3610..4008
                     /locus_tag="FE328_RS05285"
                     /old_locus_tag="FE328_05235"
     CDS             3610..4008
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194051.1"
                     /locus_tag="FE328_RS05285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05235"
                     /product="(deoxy)nucleoside triphosphate
                     pyrophosphohydrolase"
                     /protein_id="WP_004637032.1"
                     /transl_table=11
                     /translation="MTDKLIKVVGAAIVRDGHILAVERSETMTLPNLWEFPGGKIEPGE
                     TKEEALTREIQEELGLTIVVDEFINTARFQYDFGIVELSVFTVHIEAGELRLTEHSQHK
                     WLKPTELNTLTWAPVDIEAVNILSQKSV"
     gene            complement(4190..5155)
                     /locus_tag="FE328_RS05290"
                     /old_locus_tag="FE328_05240"
                     /pseudo=""
     CDS             complement(4190..5155)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387012.1"
                     /locus_tag="FE328_RS05290"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05240"
                     /product="IS30 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTHTNLTINELICIDAYAENGMKGYKIAQKIKRSPQKVYDVLNAI
                     KSGKSVKDYYEQTQENMKHRGAKRKDLSDDDLSYVTDKVSQG"
     gene            complement(5725..7020)
                     /gene="ltrA"
                     /locus_tag="FE328_RS05295"
                     /old_locus_tag="FE328_05245"
     CDS             complement(5725..7020)
                     /EC_number="2.7.7.49"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ltrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003776275.1"
                     /locus_tag="FE328_RS05295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05245"
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_244304309.1"
                     /transl_table=11
                     /translation="MTEMYHKSSSLMKQVVTKENLILAAEKVRKNDGAPGVDGMTVQEV
                     EHHIREYYPYIRKKLLNGTYQPQPVRRVEIPKGNGKARKLGIPVARDRVIQMAIKQIIE
                     PIIDKHFSNSSHGFRPGKGTETARKQCVEYYESGLKYVVDCDLKQCFDTLNHDKMMYHV
                     EQFVQDKAILKFIRKSLRCGTIELSGEFTDSETGAPQGGVISPLLCNIYLNELDKELER
                     RGHKFVRYADDFIIFKSSKRACERILKSITQFIEKDLKLQVNQEKSKTGSPTQLKFLSC
                     LIHNNFGNCRFRPTDEAKAKFKKKLKRLTKRNRPGIFTEIVKEINQVTQGWINYFGLGF
                     VKSFVRRTEEWLRRRLRQLILKRWKKGSTKIKMLQKYGLTEDEAKRIAFSRKAYWHLSQ
                     TYEVNKAITTKRLHKWGLKSLTTIAESAYARY"
     misc_feature    complement(7337..7350)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.36"
                     /tool="antismash"
     gene            complement(7637..8365)
                     /locus_tag="FE328_RS05300"
                     /old_locus_tag="FE328_05250"
     CDS             complement(7637..8365)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="FE328_RS05300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05250"
                     /product="ABC transporter permease"
                     /protein_id="WP_112787621.1"
                     /transl_table=11
                     /translation="MKNLVCAELYSFFKRKSVILFLLGTIILGLFGILYVTKLIENPLS
                     LDQYFTFIYSHFYIVSMVLITFLTLLVFHDEYENKTMKNNIFQGFSIMKILISKYIVSI
                     FIECIFLFIFTIFIILGGIELGANKGATLSFIKIVVMIFPTFFVYTFLIESCLFATKKV
                     LIGLILAYVIDQIVKLSLILVVATANSTLSFLLQQTPVFVFQNLRVDNFSIYLTISCIL
                     WEILYLIVSSILKRMELTGL"
     gene            complement(8362..9258)
                     /locus_tag="FE328_RS05305"
                     /old_locus_tag="FE328_05255"
     CDS             complement(8362..9258)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="FE328_RS05305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05255"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_111951350.1"
                     /transl_table=11
                     /translation="MESNKVISFQEVTKKYKNSKIYGIQDISFEMYEGEVLGIIGGNGS
                     GKSTLMKLIGGLLFPSEGNFKSFFRVEECGFLIEEPAFYPELSGFDNIKYYAIQKNNLD
                     MEYITHLFSIFDLFEYRKQKYKAYSLGMKKKLAIIFSLLNKPKMLVLDEPFSGLDAESV
                     ENVSRTLSKLNQEDNMTILISSHQLNEIQTLCNRFIFIDKGKLVGKISKKEWEIKSKVM
                     RKYTFINLENLKKMYDILLKERNIDCNEVLIDYKNYIIRFFEKNIDKNMWPVPEYCVSE
                     NITLNDYYIFLKEKSDK"
     gene            complement(9271..9576)
                     /locus_tag="FE328_RS05310"
                     /old_locus_tag="FE328_05260"
     CDS             complement(9271..9576)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS05310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_05260"
                     /product="hypothetical protein"
                     /protein_id="WP_112787622.1"
                     /transl_table=11
                     /translation="MLKIIDFFTGTVFQGVLGGLALISGAIILYLNNKMGLRDERIVFL
                     NIKGTNVVLWTFFVMVFILYILSPNEVQIYRKFILNSFFVAISVGAIYSIYQYIKY"
     gene            complement(9560..9802)
                     /locus_tag="FE328_RS05315"
                     /old_locus_tag="FE328_05265"
     CDS             complement(9560..9802)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635350.1"
                     /locus_tag="FE328_RS05315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05265"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_112787623.1"
                     /transl_table=11
                     /translation="MTRRSTIEVENKLYEYRVLARMSQAKLGEVIGVSRQTINSIEKNK
                     YIPSLPVALSLAKYFDVRVEEIFKIKGDDEIVKNN"
     gene            complement(10001..12643)
                     /locus_tag="FE328_RS05320"
                     /old_locus_tag="FE328_05270"
     CDS             complement(10001..12643)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024964.4"
                     /locus_tag="FE328_RS05320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05270"
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_208957734.1"
                     /sec_met_domain="DUF4135 (E-value: 5.9e-49, bitscore:
                     164.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.1e-47, bitscore:
                     157.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHRVPGSDDITLQSVVDYLITNKCRRQYYSEISFLFEPVFDTLM
                     ASKILKNNYRMIIDNNKEAIFGHAQLLVADSAILYLNNRFNKERRFVNFTDFLENCLKE
                     SNRESVLEDFYSLFPELFRLVVTYFTKMILNFTTVMDIVEENYVAIRNIYGVGELENLK
                     MNGGDRHKECKSTVLLEFNNKNLYLKWKSIDFEEKVHMIRDKLYNNKVTKIKNLRGDGW
                     YIQEELVQLPTNCLKEFYINSGKLLFLSYVLGISDLHEENIIVSGNDVYIIDSETVFEV
                     DSFLKDDIQEYDLGNSVYSTGLLPFRSFFGAIISGFNSRKEQIMYREDYSIKITSKGLI
                     KNKISNKKMKMLKNKPTNIELDFYGNSDLVIRGFQKMYEYFLKNKFELVSYIEKIFNRT
                     ETRTLIKNTHDYYLELNNSYHPYLMIDNEKRKEYIMQLKNFNTEEKKFLIDDEIPYFTK
                     KLIISPSFWHKFNSKDLELQKKLIKKSFQAESSYFSEFKQDPTPKSQAIHAYIDFLLEN
                     QLKIDNKILWLDEVYVGTDQYIDYNLILSPDNIYMGKSGILLLLNKYLCNFSSEKLANF
                     SDSLFFNQLEKVRYTILNYPKSLCGMLDGTSGMVYSLYVANKRKRIISESVIIELLKKI
                     VNNIEYDTKFDIVSGSAGLLKVLCEIYNSTDGSNEAKNVLFDLIESVESYLINNYSVKD
                     IGWRTDDSNEFYFGYAHGSSGIASSLYSSYLITNRNEALIVVKSVVSNLLNEYSMELDS
                     NWTISKGKKENCFNWCHGSPGIILFFSELNERGYENNKLKEIVRICLNKILNSDKKDVC
                     LCHGRYGNYIIAKKAMKTFNLEEFNVRLKKELADIQKIIYTEANFNKFPKSFMTGLVGI
                     FYYELEMNK"
     gene            complement(12633..14774)
                     /locus_tag="FE328_RS05325"
                     /old_locus_tag="FE328_05275"
     CDS             complement(12633..14774)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="FE328_RS05325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05275"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_208957735.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.7e-38, bitscore:
                     127.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKKVPYISQLQETECGLCCCAMILNYHGYGCTVKELRNEIEVGR
                     DGLSFNDMREVFVSKNYRTQFYEASVSSLGKISDYPLIIFWEQNHYVILEKIKNNNYYI
                     VDPAKGREKLTRERFEQSFSGIVLQIIPTEKTIKRRNKENVWFLYTNYFTDNRLQFFRI
                     FLLSLLFYLMSLFVPLMLQSIIDLSVNKKSTNFSEYVFYVSLFIPFMTFLYYFRKNSIL
                     KISCNMDTTIYQKLVDKLFKIPYEFYLSRNSSDILYRIALVRSNREFLVEFVFQGVLDI
                     GLVIIILIILFKMSVYIFGIVLIVSLISTGILLVIKDKTVKQNKIEILESTKLQGLEYE
                     SLSAMFTIKASLEDNYMKQIMMNQYDTTLSQYKKRNVLNNLYGTVVYVFTNFAPLSIFL
                     FSVLLYGKGLMSLGSTVSVYTFGNMLFGSLSSIFNTVNVFGTMKNNLLRINEIIEYNNQ
                     KNLDGISITKINTIEFKNVTFRYPGQKKNILENLSFKLNSGEKIGIVGKTGSGKSTIIG
                     LLLGLYEPVTGSILINDIDLRFINKISYKKLLGFVPQEPFVFNKSIKDNILMNRNYEIK
                     DVESAADKAEILEEIQEFPMKFETVIAELGHNISGGQKQRIIIARALLSKPGVLVFDEA
                     TSSVDNETERKISENLSKEGSILINVAHRLSTIVDSDKIIVMKNGTCIGQGNHKMLLKS
                     NDFYKQLYKEREELNKNEP"
     gene            complement(14787..16271)
                     /locus_tag="FE328_RS05330"
                     /old_locus_tag="FE328_05280"
     CDS             complement(14787..16271)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="FE328_RS05330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05280"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_208957736.1"
                     /sec_met_domain="LANC_like (E-value: 6.7e-27, bitscore:
                     90.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNELLNNLAANDNNLNTLIKDYEVEALIMDDVPIYYATPYEVDL
                     YLGTKSLKIDKYFRNSLFEEIKNKVYRLNYKSVLRQLNIIEISLLINSYNTDSSIELRT
                     EKVLKNESSFAEEVLLIEKKALNLLISSDNEIQGIFPSLVEDKFVISGLGSSLYEMGGT
                     ILMLFIDRNKLKINESLFYNIMKTVRYTKLYGDKKIGGFSGVGSFLYLNVFFYYYTKDK
                     KYLEFIKFSLKHILENYESNLNNLDYMNGISSTVILIINMLDMELQLTSDIEIMADRIL
                     KKYIENIKHYGQEFVENSGAGVAHGLSGLAYAIYKISNYYTIHDFDKLIRKAIELEDKL
                     YLEYPINNYIDPRNSKEAGLFFCYGLPGILQTRMRLVQGGMTSIKEETQIKLLYLVDSI
                     LENKINLSDMNYNVCHGMMSVLEVIVDGYRRSYIDKEKYEKVSKILLDMILSSNKSDIG
                     YSREFFLFGMGLGSKVYAYNRHKNLSLPSIMMMELI"
     gene            complement(16249..17403)
                     /locus_tag="FE328_RS05335"
                     /old_locus_tag="FE328_05285"
     CDS             complement(16249..17403)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024964.4"
                     /locus_tag="FE328_RS05335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05285"
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_208957737.1"
                     /transl_table=11
                     /translation="MLDIYNIVDKFNKEVIDFENIQIKNNCLCDYELYEGTKQNLLENL
                     RIYSIEVITFCFNDYAKNIGGTISDYWKYMDINHINEICLSFPVLVSKLKIKSSFYVNY
                     VNEIINNLDSVHDEIKFKKINGINFNLGDSHNKGKSTCIITLDNKEYIYKPRESVIEKR
                     FNAYISKFIEGYGYDIWTYSTFSVCEKVAYQPPTDQKSIEKLYYNFGLISGVIYMLNSA
                     DNHYENVIIYNEFPYFVDLECVSLHKNIIDTDSYTQKLSRRFFSCLDDSVLGTNIFPLI
                     LKPNDMEISALCGKGGTLNNFDYLNKELVFENGRFLNREVSPYITDQLNRVIVDKELVH
                     PLKYVEQIKEGFKSYCLEVMENPQSIFIFTILFTRYKNAKRIIK"
     gene            complement(17463..17648)
                     /locus_tag="FE328_RS05340"
                     /old_locus_tag="FE328_05290"
     CDS             complement(17463..17648)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="FE328_RS05340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05290"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_208957738.1"
                     /transl_table=11
                     /translation="MTELNKRLQLKRDVSTENSLKKISNTDEIHGGVTTSIPCTVMVSA
                     AVCPTLVCSNKCGGRG"
     CDS_motif       complement(17553..17648)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MTELNKRLQLKRDVSTENSLKKISNTDEIHGG"
                     /locus_tag="FE328_RS05340_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17463..17552)
                     /prepeptide="core"
                     /locus_tag="FE328_RS05340_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.00"
                     /molecular_weight="2729.3"
                     /monoisotopic_mass="2727.4"
                     /core_sequence="VTTSIPCTVMVSAAVCPTLVCSNKCGGRG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTELNKRLQLKRDVSTENSLKKISNTDEIHGG"
                     /leader_location="[17552:17648](-)"
                     /alternative_weights="2747.3"
                     /alternative_weights="2765.3"
                     /alternative_weights="2783.3"
     gene            complement(17667..17849)
                     /locus_tag="FE328_RS05345"
                     /old_locus_tag="FE328_05295"
     CDS             complement(17667..17849)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="FE328_RS05345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05295"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_208957739.1"
                     /sec_met_domain="mature_ha (E-value: 3.5e-08, bitscore:
                     29.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEELVGTAKEDFLNVICENDNKLENSGAKCPWWNLSCHLGNDG
                     KICTYSHECTAGCNA"
     CDS_motif       complement(17823..17849)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKEELVGT"
                     /locus_tag="FE328_RS05345_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17667..17822)
                     /prepeptide="core"
                     /locus_tag="FE328_RS05345_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="5528.1"
                     /monoisotopic_mass="5524.5"
                     /core_sequence="AKEDFLNVICENDNKLENSGAKCPWWNLSCHLGNDGKICTYSH
                     ECTAGCNA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKEELVGT"
                     /leader_location="[17822:17849](-)"
     misc_feature    complement(18467..18482)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.89"
                     /tool="antismash"
     gene            18477..18887
                     /locus_tag="FE328_RS05355"
                     /old_locus_tag="FE328_05305"
                     /pseudo=""
     CDS             18477..18887
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015038.4"
                     /locus_tag="FE328_RS05355"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FE328_05305"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIHLHFSESRAREVAETYLDHFKGFLHCDGYSGYNIPRLTQVH"
     gene            complement(19161..20591)
                     /locus_tag="FE328_RS05360"
                     /old_locus_tag="FE328_05310"
     CDS             complement(19161..20591)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_05310"
                     /product="hypothetical protein"
                     /protein_id="WP_172763325.1"
                     /transl_table=11
                     /translation="METGLSIRNNQNEITQIIQDSNNMYLSVLQAVGLPTENVLSSLDE
                     RKIVIANLQLVIDKMNTELIRESYYLSKFFVAVSTGLFDAALNYLWDETIKQLRIRVIN
                     GDIKYFYDVVISDERRKQFNLPEDLLKLNDFDLIKGSLEIGLITQIGYKHLDFIRYMRN
                     WASAAHPNQTELTGLNLISWLETCIKEVIATPPSSIQVKIGKLLANIKSEVIDDDQASM
                     IIPFFTELNIEKADALAKGFFGMYINEKTSQQTRSNINNLAPELWQIISEEVKSNFGIR
                     YATFLANGDNQAKNEAKRFLEVVGGMSYLPDTVKTPIIKKSLENLMMAHNSFNNFYNEP
                     SFARQLRAVVGDHGTIPPQMNFLYVKVIVSVFLTNGSGEAWGANPIYTELIKNFDAQQS
                     LIALTSFMDESIRSKLQFSLCQKKFTEMIGYIESNVTSEGVLDLLVEIRSKVKFLQDIS
                     NEDKLIDKIRFFQKNYLK"
     misc_feature    complement(20630..20644)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 23.46"
                     /tool="antismash"
     gene            complement(21141..21335)
                     /locus_tag="FE328_RS05365"
                     /old_locus_tag="FE328_05320"
     CDS             complement(21141..21335)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE328_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE328_05320"
                     /product="hypothetical protein"
                     /protein_id="WP_112788307.1"
                     /transl_table=11
                     /translation="MIERSRYLSSQELTEEVAHDSALLQLIAEVNISNFNMKIGEYQDI
                     MEHLYANKDSSRKSGYIKS"
     misc_feature    complement(22164..22173)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.51"
                     /tool="antismash"
ORIGIN
        1 aactgatccc gtaatagaaa ctaaatcaac atccgggcta ctagctaatg ccgagccgaa
       61 ctcacgatct ccagacagaa tattgacaac tccagctggt agatcaaccg cttctaacaa
      121 ttgtgcaaaa atcagcgcat tattcggagc actactggac ggtttgacaa tcactgtatt
      181 acccgttaga atagctggag ctactttccg tgcaataagg aagaatggat aattccacgg
      241 caaaatcccc gcaacaacgc caactggttt cttgaaaatc ataatatttt cattcggact
      301 atcgcttggc actatctctc cttcatactt acgtgcccac ccagcataat acttgaaata
      361 ttctgctgtt gcttccactt ctcccattgc ctgctctaag accttcccga cttccgtaga
      421 aataaccttc gcaaatgttt ccttatgctc taaaattaaa tccgataatt gatacaagta
      481 ttccgcacgt tcattggatg ggacatgttt ccaagacttc tgtgcccgtc gagctgcctt
      541 cagcgctcga tctaagtcct caagtgaagc ttgcggcact tgattcagta cttctccagt
      601 ggatggatta atattatccc ctaacgtccc ctccgaactc tctacaaact gcccatcaat
      661 atacatctta tactgatcta acttcaattc cattcgtttc ataaatcctc tcttcataaa
      721 ttaataaacc gtttacatta tagtaataat ctaccatata ttaatcaaag aaagcaactc
      781 tctgaactga taaaatcact cgccagatac aaattcaatt aaaaacaagc gctaacaagt
      841 taaccaaccc tctaacactt cactttttat attttccacc tgcttttgtg aaatctttat
      901 tgtgtatatt gaataaaaaa ataacccgct cagagatgtc aaacctctaa gctaggttac
      961 cactaattgt tctctatcct atttaaacag cgactgacta ctctgtttta tcagtcttct
     1021 gattcaccat ttgatgatac aacttccgca ggcggtattg gtcttcatct gtaatcggtg
     1081 agttgcggcg atattgactg agccgatatg ccgtcgcttc gctcgtaatc gactgcttcg
     1141 tctgcttaat atccttccac agctcattcg ctgacttccg tgtcgccccg cgctggaaaa
     1201 tcatccactg ctcagccaaa tcactcgtcg ccaccttcac attcgaaacc aaaaagttct
     1261 cttcacccac cgaccgctca atatactcat ccgccgtctc accctcctgc gtgaagatca
     1321 cctccagatc atactgctca taccgttgcg taatccccgg caccaactgc gcatcgaaca
     1381 ccacaatcac ctcaatcccc gcgaacgccc cataattact caactcatgc aacaactcat
     1441 cacgagccgt cccaatctca tcccgttgct gcagccgctt caaatttggc cacgccccaa
     1501 tcatattata accatccaca tacagaatct ctcgcttcac caactcaccc ctctcatcat
     1561 actgtcttac ttattttaac acatttattg tggtatcata gaataaacta tttataacac
     1621 gttaggagcc ccgcttatgt caaaaaaatg tcgctcagcc ctctcccgaa tcttcagctt
     1681 ctgttgcctg ctgatcatca ctattgccct attccgccct gccagcgagc ccgttcatgc
     1741 agcagaagac gtacagttga ttgttgaata tgaccacgta gacaatatgc ctaacgaaga
     1801 ccaactgccc ccacaagtca cccaagtcca cacgtctcgg tatacaccga cacgtgctct
     1861 cactattccc agacaataca tccacctcct acgaagccaa gcccacatca agtctatccg
     1921 ctccaaccaa actgtcgttc cattagaagc tgatgccact gagagaactc ctacctccgc
     1981 caactaccct tggaacttac agacgattgg tgctgacatt gctcaccaac aaggcattac
     2041 aggaaaaggg gtcaatattg cagtagtcga tactggcttc tacatcgatc atccgaatat
     2101 cacttttgct ggaggagcct ctatcttcaa cgatgatcct tggacgaacg accacatggg
     2161 acacggcacc cacgtcgctg gtattatcgc tgccgccgcg gattcagaat tccccggcgt
     2221 cgctcccgat gtcaacctat atggagtaaa agtctaccac aaagatgtgc ttgatgctga
     2281 taacacgcct agcaccacag tctacaactt gacagaagga atctatgcag ccatgcgaca
     2341 aggtgtggat atcattgtcg tcagttccgg cttccaaggc gaagatgaag gcatgcgcca
     2401 agccgtccaa caagccactg accaaggcat cgtcatctac agcgccagcg ggaacgggca
     2461 gccagctgtg gattacccag cagcctaccc tgacgttatc tctgttacga gcatcgatca
     2521 attccagcac gccgcctctg acatcattgc tggccctgag aatgacctca cagcacctgg
     2581 cgtcgagatt actagcctct cctcacccga tagtgtctat ggctatccgt tcgcaacctt
     2641 gagcggcagt tcccaagcaa ccccacatgc agcgggcatt actgcacttt taatgcaaaa
     2701 ataccaaata actgcctcag aagcgaccga acgtttactc gaacaagcac aagacttaga
     2761 tgatgcagac ttcttcggac atggcttagt ccaattctta gctcccgaag accgcaagcc
     2821 aactaacaat atcgaccgca actcaagcca tacggacgcc gcgaccaaag aaccctccga
     2881 actctactgg gctgaaccca ctgctcaagg aacccgctct ttccttgctg acgaatattt
     2941 cgcccaagtt caagcacaag gcatccttgc tttaacttat acggataccg gcctggatac
     3001 cttgcgtctc aacgaagcac aagtcagaac gatgaaatcg cgccagatca ccttgcgctt
     3061 ctatctaaat gatatcgaat gggaggtccc cgctgatgcc ttagataccg gcgaagcact
     3121 cttcaaattc acggatgtga ccacccatga tgctattgaa acagcctcag cacagtctac
     3181 ggtcatcaaa ttcgaaatcc aacagaatgg cgcaccgaag accaccttca cccaaccgat
     3241 gacctatcgc ttcctcgccc aagataattg ggaggatagc acagacatct acatcttaga
     3301 taacgaacag aactggactg ccctagatgc tgaacacagt ggccactact tacaacgaac
     3361 cactaaccaa actggcacct tcgccgtctt caataccaaa gatatcaaca acactacccc
     3421 agctcaatct aaccctaact ccccaacacg cacactgtgg ataatcgtgg ggataagtac
     3481 tctcgtgcta gctggattga taattatcat gaagcactgg atcaaccccc gccaacagta
     3541 gctttccgtc agtgaacatg ataaaatgaa actgcaaaaa gagagtattt aatatagaaa
     3601 ggaattaata tgactgataa attaataaaa gttgtaggag cagccattgt ccgcgacggt
     3661 cacatcttag ctgttgagcg ttcagagacc atgactttgc caaacttgtg ggagttcccc
     3721 ggtggcaaaa tcgaacccgg cgaaacaaaa gaagaggcac ttactcgcga aatccaagaa
     3781 gaactagggc ttacaattgt tgtcgatgaa tttattaata cagcacgctt ccaatatgat
     3841 tttggtatag ttgagctttc tgtctttact gttcatattg aagctggtga gctcagacta
     3901 accgaacata gccaacataa atggttaaag ccaactgaac taaacaccct cacatgggca
     3961 cccgttgata tcgaagctgt taatattctg tcacaaaaat ctgtttaacc aaaaggacta
     4021 gcctccacag ctaatctttt ttaagtcttg attgtcaaat taaaatagaa attttgatca
     4081 ctttgtggtc tagatcctcc attcctaaat ggcgcgactt ccaaagaaca gaagtggttt
     4141 tcttctgttc tttgggagtt gcttaaccaa ccgaacaacg tgagggcggt cattcagtga
     4201 aaatttcaga taggtgatat cctgtctgag cttcaaatac ctcgattggg gtacggtatt
     4261 tgagagaacg ccgtggaata tggttgcgat aatccgatac agattggata aatgcttcgt
     4321 ccaccgtgtt aaaatccatt tgtttcgcca gtccatcgtg tcgtagtaag ccatttgatc
     4381 gttcctttaa tccacgctgc cctggacagc caggatcagc aaagaaaata tcaatgtcat
     4441 ggtcgttaga caaacttttc cagttagaaa attcttttcc acagtcaaat gtgattgatt
     4501 taaacaaatg atgtggacaa tgggctaaaa attgactcat tcgatgatcc acagctttcg
     4561 ccgttcgacc atccagttta agtgtgataa tgattttgga ttgacgttca accagtgtga
     4621 taatcgcact tttatgtttt ttgccaacaa ttgtatcgcc ttctagatgc ccaaattccg
     4681 tatcaaactg agaacagcta tcttttcgtg aatgaataga gcgtgtagaa gagtgtttac
     4741 cacgcgtttc ttaatgtcca ttcggtttcc gtttaccttt taagggaagt gttgagatat
     4801 ttagtcgctc atcatcctta aatcgtctat ataaagtttt ggaagacagg ttgagttgac
     4861 gttctcctcg tccaataata acgtctggtg tctatccttg actgactttg tccgtcacat
     4921 aggataaatc gtcatcggat aagtcttttc gcttggcgcc gcgatgcttc atattctctt
     4981 gcgtttgttc atagtagtcc ttgacagact tacctgactt tatggcgttg agcacatcat
     5041 acactttctg aggagatcgc ttgatctttt gggctatttt gtaacctttc atgccatttt
     5101 cggcataagc atctatgcaa atcagttcat ttatggtgag attggtgtgg gtcattgtgg
     5161 tgcatctcct attcttctta gagggttgat ataggatgat tgtaccacag atgacccttt
     5221 taaatttcta ttttaatttt acaatgaagg tgaataaaaa attatttaat agcattaaca
     5281 acacaataat ccctttattt ggaatgttat tttaatcatt ttctactgtc tattcaggaa
     5341 aaatttaatt tgttgtcatt gatatgtata ctccttatgt ttatttagtg aagaaatatt
     5401 ctgtatcgtt caatacaaca catcagaaac agaaactatt gaatcactta aaacacatgc
     5461 cgttaacatc ctttgtttaa aacttattgg acgaagcaga acttgtagac aaacggtttc
     5521 ctatttgaat ggtcaataga gtgtttaaat aatctaatat caaaatgttg atccgagata
     5581 tctctgattt tcgtaacttc tataattcaa attacgaatt ttcgtccaac aaagagccat
     5641 acaaaccaat cgagtaggat actagccatt aattgactag tcgacctctc acaccaccgt
     5701 acgtacggat ccgtatacgg cggttcaata ccttgcataa gcagactccg ctatggtggt
     5761 taatgatttt aatccccatt tgtggagtct ctttgttgta attgccttat tgacttcata
     5821 tgtttgagat agatgccaat aggctttccg agagaaggca attcgttttg cctcatcttc
     5881 tgttagtcca tatttctgaa gcatcttaat cttggttgag cctttcttcc aacgtttcaa
     5941 tataagctgt ctaagtcgcc ttcgcaacca ctcttcagtc cttctcacga agcttttaac
     6001 aaaacctaac ccaaagtaat taatccaccc ttgagtcact tggttgattt ctttcacaat
     6061 ctctgtaaat attcctggtc gattgcgttt ggttaatctc ttaagttttt tcttgaattt
     6121 tgctttcgct tcgtccgttg gtcggaatcg acaattgccg aagttgttgt ggattagaca
     6181 gctcaagaac tttaactgag tcggacttcc tgtcttgctc ttttcttgat taacttgaag
     6241 tttcaggtct ttttcaatga attgagttat actcttcagg attcgttcgc atgctcgttt
     6301 tgatgattta aagattataa aatcatccgc atatcgcaca aatttatgtc cgcgtcgttc
     6361 aagctcttta tctaactcat tcagatagat attacacagc aatggtgata tcacaccacc
     6421 ttgtggtgca ccagtttcac tatccgtaaa ttcgccagat agttcaatgg tgccacatct
     6481 caatgattta cgtatgaatt ttaagatagc tttatcttga acaaattgtt ccacgtgata
     6541 catcatctta tcatgattaa gtgtatcaaa gcattgcttc aaatcacaat ctaccacata
     6601 ttttaagcca gattcgtaat attctacgca ctgtttccga gcagtttcag ttccttttcc
     6661 tggtcgaaat ccatgactac tattagaaaa gtgtttatct attataggct caattatctg
     6721 tttaatagcc atttggatta ctcgatcacg tgctactggt atgcccagct tccgtgcttt
     6781 tccattgcct tttggaattt ccactcgtct cactggttgt ggttgatacg ttccattgag
     6841 tagcttcttt ctgatatatg gataatattc tctgatatgg tgctcaactt cttgaacagt
     6901 cataccgtca acaccaggag ctccatcatt ctttcgaact ttttcggctg ctagtattaa
     6961 attctctttt gttacaactt gcttcatcaa cgatgaagac ttatgataca tttctgtcat
     7021 ttcttcctag gagtatactt aacacatcca tatcttgtcg ttttcagttc cacctacttg
     7081 actcattgga ttgccagctc tcgctgtttt ctgttgtaat cgcaactcct aacctccaat
     7141 ctttactctg tattgatatt gttctgtcct tcatgcgcaa tgcgcactac tatgacgtcg
     7201 gctgacttct gtctattcgc tattgctacg gtttcccgct agacagacct ccccgggtaa
     7261 gagcgacaac cttccaccca tgtcactgcc tcatttacct gacggtgctc gtacagtatt
     7321 ggacttcact ttgtattgca agcttatcca cacctatccg gccttcttta tgagatttct
     7381 gttcgtcagt gcaggtgttt gcctctggct tccttcagat tccacctcac gatggacacc
     7441 cttgcctttg gctaataatt cctactgtaa aggcttatag tgaactttca ccaccaagtt
     7501 gtcgcccatg ccggacgcac aataaaaaaa tccagaggag aaaatcctct ggattcaacg
     7561 tagacgtgat tctacaattt tttatcaaca agtatccaac ttttctacaa agggtagtca
     7621 gaattgtgta tcctctttac aggcctgtta actccatcct ttttagaatg ctacttacga
     7681 tcagatacaa tatctcccac aatatacaac taatagttaa atatattgaa aaattatcaa
     7741 cccttaaatt ctgaaaaaca aatactggag tctgttgtag caaaaaactt aaagtactat
     7801 tggctgtagc tacaaccaat atcagactta atttaactat ttgatctatt acataagcta
     7861 aaatcaatcc aattaaaacc ttttttgtag caaacaagca gctttcaatc aaaaacgtat
     7921 atacaaaaaa agtaggaaat atcataacta ctattttgat aaaactaaga gtagctcctt
     7981 tatttgcgcc taattctatt ccacctaaaa taatgaatat tgtgaaaatg aacaaaaata
     8041 tgcactcaat aaatattgag actatatatt ttgagatcaa tattttcatt atagaaaatc
     8101 cttggaaaat attgtttttc attgttttgt tttcatattc atcatgaaaa acaaggagcg
     8161 ttaaaaatgt tattaatacc atcgaaacta tatagaaatg ggagtatata aaagtaaagt
     8221 attgatctaa tgataacgga ttttcaatta atttagtgac atacaaaatt ccaaataatc
     8281 ccaatattat agtgcccaat aagaacaata tcacactttt tctcttgaaa aaactataca
     8341 attcagcaca aactaaattc ttcatttgtc cgatttctcc tttaaaaaga tataatagtc
     8401 attcaaagtt atattttcac taacacaata ctctggcaca ggccacatat tcttgtctat
     8461 atttttttca aaaaatctaa taatataatt tttatagtca attaaaactt cattacaatc
     8521 gatatttctc tcttttaaca agatatcata catttttttt aaattttcta aatttataaa
     8581 tgtatacttt ctcattactt tgctttttat ttcccattct tttttactaa tttttcctac
     8641 taattttccc ttgtcgatga atataaaacg attacataat gtttgaattt catttaactg
     8701 atgactagaa ataagtatag tcatattatc ttcttgattt aattttgata gtgttctaga
     8761 aacattctct actgattctg catctaaacc actaaaaggt tcatctaaaa caagcatttt
     8821 aggtttgttt aataaagaaa aaattatagc taactttttt ttcatgccta aagaatatgc
     8881 tttatatttt tgttttctat attcaaataa gtcaaatata gaaaacaaat gcgtaatata
     8941 ttccatatct aagttatttt tctgaattgc ataatactta atattatcaa acccgcttag
     9001 ttccggataa aaagcaggtt cctctattaa aaaaccacat tcttcaactc gaaaaaaact
     9061 tttaaaattc ccttcactag gaaacaataa tcctcctatt aatttcatta atgtagattt
     9121 tccagaacca ttccctccaa taattcccaa tacctcccct tcatacattt caaaagatat
     9181 atcttgaata ccatatattt tactattttt atatttttta gttacttctt gaaaactaat
     9241 tactttgtta gattccatag ttgtttgctc ctaatactta atgtattgat agattgagta
     9301 tatagcaccc acgcttatag ctacgaagaa tgaatttaaa ataaattttc tatatatttg
     9361 gacttcattt ggactgagta tataaagaat aaataccata acaaagaatg tccataagac
     9421 tacatttgta ccttttatat ttagaaaaac aattctttca tctcttaatc ccattttatt
     9481 atttaaatac agaataattg caccagaaat caaagctaat cctcccaata ctccttggaa
     9541 taccgtacct gtaaaaaaat caattatttt taacaatttc gtcatctcct tttattttaa
     9601 atatttcttc tactctaaca tcaaaatact tagctagact taacgctact ggtaaagaag
     9661 gaatgtattt atttttttca atagagttaa ttgtttgcct agacacgcct atcacttctc
     9721 ctaattttgc ttgtgacatt cttgcaagta ctcgatattc atacaattta ttttcaactt
     9781 caatcgtact tcttcttgtc atgacttacc tcctataaat attgtaaagc taactttaca
     9841 aattgtcaag ttaatttaat gctttgcaat tgatttatgt aattattact ttacttaaac
     9901 ctcagacttt cataatataa atactttcaa gaataaaagg cagcacgaaa tcattttagc
     9961 tgcttttcta tattaactca aacaagatat atagtaaatt ttatttattc atttctaact
    10021 cataataaaa tattcctacc aatcccgtca taaaagattt tggaaattta ttaaaattcg
    10081 cttcagtgta aataattttc tgaatgtcag caagttcttt ttttaatcta acattaaatt
    10141 cttctaaatt aaaagttttc atagcttttt ttgctataat ataattacca tatctaccat
    10201 gacacaaaca tacatctttc ttatcagaat tcaatatttt atttaaacaa attcttacta
    10261 tttcttttaa cttattattt tcatatcctc tttcatttaa ttccgagaaa aataaaataa
    10321 ttcctgggga accgtgacac caattgaaac aattttcttt tttcccttta ctaatagtcc
    10381 agttactatc tagttccatc gagtactcat ttaataaatt actcacaaca ctttttacta
    10441 ctattaatgc ttcattacgg tttgtaatta aataagacga atataaactc gaggctattc
    10501 ctgaagatcc atgggcatat ccaaaataaa actcattaga atcatctgtt ctccatccta
    10561 tatctttaac tgaataatta ttaatgaggt aactttctac agattctatc aaatcaaata
    10621 aaacattttt ggcctcatta ctaccgtcag tactattata tatttcacat aaaactttaa
    10681 gtagccctgc agaaccacta acgatatcaa acttagtatc gtactctata ttgttaacta
    10741 tttttttcaa taactcaata ataacacttt cacttattat tctttttctc ttatttgcta
    10801 cgtataaaga atagaccatt ccacttgttc catctaacat tccacataag cttttgggat
    10861 aattcaaaat agtgtaacga actttctcta attgattaaa gaatagacta tcagaaaagt
    10921 ttgcaagttt ctcactagaa aaattacata aatatttatt aagtaacaac aaaattccag
    10981 atttccccat ataaatatta tctggagaaa ggattaagtt gtaatcgatg tattgatctg
    11041 ttccaacata tacttcatcc agccatagaa ttttattgtc tatcttcaat tgattttcta
    11101 atagaaaatc aatgtatgca tggatagcct gtgatttagg tgtcggatcc tgtttaaact
    11161 ctgaaaagta actactttca gcttgaaacg atttttttat taattttttt tgaagttcta
    11221 aatctttgct attgaattta tgccaaaaag aaggtgatat tatcaatttt ttggtaaaat
    11281 acggaatttc atcatcaatt aagaattttt tttcttcagt attaaaattc ttcaattgca
    11341 taatatattc ttttcgtttc tcattgtcta tcatgaggta tggatggtaa ctattgttta
    11401 attccaagta ataatcatga gtatttttta ttagcgttct tgtttcggtt ctattaaata
    11461 ttttttcaat gtagcttact aattcaaatt tattctttaa aaagtactcg tacattttct
    11521 gaaaccctct tatcaccaaa tcagaatttc cataaaaatc taattcaata tttgtaggtt
    11581 tattttttaa cattttcatt tttttatttg agattttatt ctttattaac ccttttgaag
    11641 ttatttttat agaataatcc tctctataca taatttgttc ttttctagag ttaaatccag
    11701 aaataatagc tccaaaaaaa gacctaaaag gaagtaaccc tgtcgagtac acagaattgc
    11761 ccagatcata ttcctgaata tcatctttaa gaaaactatc cacttcaaat actgtttcac
    11821 tatctataat atatacatca ttgccactga caataatatt ttcctcatgc aaatctgata
    11881 tacccaaaac atatgagaga aataacaatt taccactatt aatgtaaaac tcttttaagc
    11941 aattagttgg aagctgcact agttcttcct gtatatacca accatctcca cgtaaatttt
    12001 ttatctttgt taccttatta ttatataatt tatccctaat catatgaact ttttcttcaa
    12061 aatcaatact tttccatttt aaatataggt ttttattatt gaattcaagc aatactgttg
    12121 atttacattc tttatgccta tctcctccat tcatttttaa attttctaat tctcccacac
    12181 catagatatt tctaattgca acataatttt cttctacaat atccattact gttgtaaaat
    12241 tcaaaatcat ttttgtaaaa tatgtgacta ccaatctaaa aagttctggg aataatgagt
    12301 aaaaatcttc caaaacactt tctctattcg actcttttaa acaattttct aaaaaatcag
    12361 taaaatttac aaatcttctt tctttgttaa acctattatt taaatacaat atggctgaat
    12421 ccgctactag taactgtgca tgaccaaaaa tagcttcctt gttattgtct ataatcattc
    12481 gataattatt ttttaatatt ttactggcca ttaatgtatc aaaaacaggt tcaaataaga
    12541 aagaaatttc tgaataatat tgccttctac acttatttgt aattaaataa tccacaacac
    12601 tttgcaatgt aatatcatca ctaccgggca ctctatggtt catttttatt tagttcctct
    12661 ctttctttat acaattgttt ataaaaatca ttcgatttta atagcatttt atggtttcct
    12721 tgccctatac aggtaccgtt cttcataact ataatcttat ccgaatcaac aattgtactt
    12781 aatctatgag ctacattaat taatatacta ccttctttgc tcaaattttc gctaattttt
    12841 ctttcggtct cattatctac agagcttgta gcttcgtcaa aaacaagtac ccccggcttg
    12901 cttaacaaag cccttgctat aattattctt tgcttttgac cacctgaaat attatgtcca
    12961 agttcagcga taactgtctc aaatttcata ggaaattctt gtatctcttc caatatttca
    13021 gctttatcag ctgcactttc tacgtccttt atttcgtaat ttctattcat taatatatta
    13081 tcttttattg atttgttaaa aacaaacggt tcttgtggaa caaagcctaa caatttttta
    13141 tacgaaattt tattaataaa ccttaaatca atatcattaa taagtatact tcctgtcact
    13201 ggctcatata gacctaatag taaccctatt attgttgatt tcccagaacc agtttttcca
    13261 actattccaa ttttttctcc cgaatttagt ttgaaagata aattttctaa tatatttttc
    13321 ttttgacctg gatacctaaa tgtcacattt ttaaattcta ttgtattaat ttttgttata
    13381 gatattccgt caagattttt ttgattgtta tactcaatta tttcatttat tcgtaataaa
    13441 ttatttttca tagtaccaaa aacatttaca gtattaaaaa tagaagacag gctaccaaat
    13501 aacatattgc caaatgtgta tacagagact gtacttccta agctcattag tccttttcca
    13561 tatagtaata cactaaataa aaagatactc agtggcgcaa aatttgtaaa tacgtatact
    13621 acagttccat ataaattgtt taatacattt ctctttttat attgacttag tgtagtatca
    13681 tactgattca tcattatttg tttcatataa ttatcttcca atgaagcttt aattgtgaac
    13741 atagctgaca atgattcata ttctaacccc tgtaattttg tactttctaa tatctcaatt
    13801 ttattttgct taacagtttt atcttttatt actagaagta ttcctgtaga aatcaaggaa
    13861 acaattagca caatcccaaa aatataaaca ctcatcttga ataagattat taggataatt
    13921 ataaccaatc ctatatctaa aacaccctga aatacaaatt caactaaaaa ttccctattc
    13981 gaacgtacta aagctattct atataaaata tcactagagt ttcttgacaa ataaaattca
    14041 taaggtattt taaacaattt atctactagt ttttgataaa ttgttgtatc catgttacaa
    14101 gagatcttca atatactgtt tttcctaaag taataaagaa atgtcatgaa cggaataaac
    14161 aaacttacat agaaaacata ttcactaaaa tttgttgatt ttttatttac agataagtca
    14221 ataatactct gaagcattaa gggtacaaaa agactcatta aataaaacag caaagacaat
    14281 aaaaagattc taaaaaactg taatcggtta tcagtaaaat aattagtgta cagaaaccaa
    14341 acattttctt tatttcttct tttgattgtt ttttcagtag gaataatctg taaaacaata
    14401 ccagaaaatg actgttcaaa tctttctcta gtaagctttt ctcttccttt agcagggtct
    14461 actatataat aattattatt ctttatcttt tctaatatca cataatgatt ttgttcccag
    14521 aaaatgatta acggataatc agatatttta cccaaagacg atactgaagc ttcataaaat
    14581 tgcgttctat aatttttact tacaaaaact tctctcatat cattaaagga taatccatcc
    14641 ctaccaactt ctatttcatt tcgtaattct ttaactgtac aaccataacc atggtaattt
    14701 aaaatcatag cgcaacagca taacccacac tctgtttctt gcaattgact aatatatggt
    14761 actttcttca acattatcac ctctaattaa atgagctcca tcatcatgat agaaggtaaa
    14821 cttaggtttt tgtgtctgtt atatgcataa actttactac ctaatcccat accaaataag
    14881 aagaactctc gagaatagcc tatatcactt ttatttgaac ttaatatcat atctaataaa
    14941 attttggata ctttttcata tttttctttg tcaatataac ttcttctgta accatcaact
    15001 attacttcta aaacactcat cataccgtga caaacattat aattcatatc acttaaattt
    15061 attttatttt ctagtatgct atctactagg tacagtagct taatttgtgt ttcttcttta
    15121 atagaagtca ttcccccttg cactaatctc attctcgtct gtaatattcc aggaagtcca
    15181 tagcaaaaga aaagtccagc ttctttacta tttctaggat ctatataatt atttatagga
    15241 tattctaaat acagcttatc ctctaactca attgcttttc ttatcaattt gtcaaaatca
    15301 tgtattgtat aatagttact tatcttgtat atagcataag ctaatccaga caatccatgt
    15361 gccacaccag ctccgctatt ttcaacaaac tcttgtccat agtgtttaat attttctata
    15421 tattttttta gaattctatc tgccattatc tctatgtcag aagtcaattg caactccatg
    15481 tccaacatat ttattatcag tattactgta gaactaattc cgttcatgta atctaaatta
    15541 tttaagttag attcataatt ctctaatatg tgttttaagc tgaattttat aaattccaaa
    15601 tattttttat cttttgtata ataataaaaa aagacgttta agtataagaa agaacctact
    15661 cctgaaaacc ctccaatttt tttatcacca tatagttttg tgtacctaac cgttttcatg
    15721 atgttataaa ataatgattc attaattttc agtttatttc tatcaataaa taacattagt
    15781 attgttcctc ccatttcata tagagaagaa cccagtcctg atataacgaa tttatcctca
    15841 actaatgaag gaaatatacc ttgtatttca ttgtctgaag atattagtaa attaagagct
    15901 tttttttcta tcaataatac ttcttcagca aacgaacttt cattttttaa aactttctct
    15961 gtacgtaact ctatactact gtctgtattg taagagttaa tcagtaaaga aatttctatt
    16021 atatttaatt gacgtaatac tgacttataa ttcaacctat atactttatt ttttatttct
    16081 tcaaataaac tatttctaaa atatttatca atcttaagac tttttgtccc taagtacaaa
    16141 tctacttcat atggagtggc ataatatata ggaacatcat ccattatcaa tgcttcaact
    16201 tcataatctt ttattaaagt atttaaatta ttatcattag ccgcaaggtt atttaataat
    16261 tcgttttgca tttttatatc ttgtaaatag tatggtgaaa ataaagatag attgaggatt
    16321 ttccataact tctaagcaat aacttttaaa tccttctttt atttgttcaa catattttaa
    16381 gggatgaacc aactccttat ctacaataac tcgattcaac tgatctgtaa tatatggcga
    16441 tacttctcta ttaagaaatc tgccattttc aaaaactaat tccttattta aataatcaaa
    16501 attatttaac gtgccacctt taccgcatag tgcagaaatc tccatatcat ttggtttcaa
    16561 aataagaggg aaaatatttg ttcctaaaac agagtcatct aaacaagaaa aaaatcttct
    16621 tgataatttt tgggtatatg aatctgtatc tatgatattt ttatgtaacg atacacattc
    16681 taaatccaca aaatacggga attcgttata tataatgaca ttctcatagt gattatcagc
    16741 gctgttaagc atataaatga cacctgatat caatccaaaa ttataatata atttttctat
    16801 tgatttttgg tcagttggag gttgatatgc tactttttcg caaacagaaa atgtagaata
    16861 tgtccagata tcataaccat acccttcaat aaatttagat atatacgcat taaatcgctt
    16921 ttctatcaca ctttccctag gtttatatat atattccttg ttatccaatg taataataca
    16981 agttgatttc cccttattat gactatcacc taaattaaaa tttattccgt tgattttttt
    17041 aaattttatt tcatcatgca ctgaatccaa attattaata atttcattta catagttaac
    17101 ataaaaagaa cttttaattt ttaatttgct taccaaaact ggaaaactca aacaaatttc
    17161 atttatatgg ttgatgtcca tatatttcca ataatcacta atagtacctc ctatattttt
    17221 tgcataatca ttaaaacaaa aggtaatcac ttcaatcgaa taaattctca aattttctag
    17281 taaattttgt tttgttcctt catataattc gtaatcacac aagcaattgt ttttaatttg
    17341 tatattttca aaatcaatta cttctttatt gaatttatca acaatattgt aaatatctaa
    17401 catagtaacc tccaaaaaaa aagtaatggt agtatagact gccattactt ttaaaattta
    17461 aactagcctc taccgccaca tttattcgag caaacaaggg taggacatac tgccgcacta
    17521 accatcactg tacatggaat tgatgtagta actcctccat gtatttcatc agtattagaa
    17581 atttttttca agctattttc tgttgaaaca tctcttttta attgtaatct tttgttaagt
    17641 tcagtcatta tttatccccc caataattat gcattacaac cagcagtgca ttcgtgtgaa
    17701 taagtacaaa ttttaccatc attgcctaaa tgacaagaaa gattccacca cggacatttt
    17761 gctccactat tttctagctt gttgtcattt tcacaaataa cattcaaaaa gtcttcctta
    17821 gccgttccta ctaattcttc ttttttcatc ctcaatccct cctttctaaa acaattcaaa
    17881 ccccaaacaa tcaagttaac taatctaaaa atcaagttaa ctttacatat attttatatt
    17941 atacaaagga attaatcaag agtttatatg taaaatttag ttgttagatt aattttttta
    18001 agttaattat aatgttgatt caaaaataat tcacgaggtt ttatctatca ctaaaataac
    18061 agctaggaca gcaacacaat tactatatag ttatgctaca acaaatgtaa gcgcccatgt
    18121 tttaggcgac tagttccacc tcaaaaaatc ctctaaaata gttaatgtaa gataaaaact
    18181 attgagagga ttttttgtat gtcaaaacca gaaattatca aagtaacaca gacaaagact
    18241 cactccgaaa aacttaactc cactcaaatt atgagtatca aaacacgtgg gttgtccctt
    18301 attgtatatg actgtatctc cttagatcag ttgagcattt tattaaaggc ggtgaatgaa
    18361 cgtgattatt aattatgacg cattcgatca catttatatt gtatgcggaa agactgattt
    18421 aagaaaagga attgacggat tagctgaaat tatctgatct gactatgatt atgattatga
    18481 ttcatcttca ttttagcgag tcacgtgcac gagaagtggc cgaaacctac ttagatcact
    18541 ttaaaggatt tctgcattgt gatggctact ccggatataa cattccgaga ctgacccaag
    18601 ttcattgatt ggctcacatc cgtcggaagt ttactgatgc ctttcataca aagcatacca
    18661 ccggcgaagc agtaaatggc gttaatttct gcaataaact gttcaaagtt gaagaactga
    18721 ttaaacagaa gcaactgaat ggcacgcagc tactagatta ccgtcatact cacttgaagt
    18781 cactgcttga tgagttcacc gaatggttag accatcatca gtatctaacg aagtctaaac
    18841 tgggcaaagc cattatctat gcccgtagaa tgcttccgag tttgtagtta ttactcgatc
    18901 atgctgggtt gagcattagt aacaattccg ctgagcgagc tatgagaata cccgctttgg
    18961 gacgtataaa cacaagccga ttctatctga taatcattat atcagagtgg aattggcttt
    19021 ttctatacgc ttaaatcatg ggtgctttca aaagaataca ctcatgcaag tgtatttttc
    19081 ctcaaaatct actatagact agttttacaa gatacgaaaa aatatagaat ttatgtgggc
    19141 aaggagatgt agagataaaa ttattttaaa taattttttt gaaaaaatct tattttatca
    19201 attaatttat cctcgttaga tatatcctgt aggaatttca ctttacttct aatttctact
    19261 aataaatcta aaactccttc tgatgtaaca ttagattcaa tatatcctat catttctgta
    19321 aacttcttct ggcataaaga aaattgtaac ttactcctta ttgattcatc cataaaagaa
    19381 gttaatgcaa tcaatgattg ctgtgcatca aaatttttaa ttaattcagt ataaatagga
    19441 tttgcccccc atgcttctcc actcccatta gtcaaaaata cagatactat tactttgaca
    19501 tataggaaat tcatttgtgg aggaatagta ccatgatcac ctactacagc acgcaattgt
    19561 cttgcaaatg aaggttcatt gtaaaaatta ttgaaactat tgtgagccat cattaaattt
    19621 tctaaagact ttttaattat aggagttttt actgtatctg gtaaataaga cattcctccc
    19681 acaacttcta agaacctctt tgcttcattt ttagcttggt tatctccatt tgccaaaaat
    19741 gttgcatatc taataccaaa atttgatttt acttcttcag atattatttg ccataattca
    19801 ggagctaaat tatttatgtt acttcttgtc tgctgacttg ttttttcatt aatatacata
    19861 ccaaaaaagc cctttgccaa tgcatcagct ttttcaatat ttaattcggt aaaaaatgga
    19921 attatcattg aagcttggtc atcatcaatc acttcagact taatattcgc taacaatttg
    19981 cctattttaa cttgtatact tgatggtggg gttgcaatca cttctttaat acatgtttct
    20041 aaccacgaaa ttaaatttag tcctgttaat tctgtttgat tgggatgtgc tgcacttgcc
    20101 caattcctca tatatcgtat gaagtctaaa tgcttatatc ctatttgtgt aatcaagcca
    20161 atttccaatg atcctttaat taaatcaaaa tcgtttaact tcaataagtc ttctggtaaa
    20221 ttaaattgtt ttcttctctc atcacttatt acaacatcat agaaatactt aatatctccg
    20281 tttataactc taatccttaa ttgtttaatt gtttcatccc ataaataatt taatgctgca
    20341 tcaaatagcc ccgtcgatac tgcaacaaaa aatttggaca aataatacga ttctctaatc
    20401 aattcagtat tcatcttatc aataaccaac tgaagatttg ctattacaat tttccgttca
    20461 tctaatgaag acaaaacatt ttctgttggt aaccccaccg cttgtaaaac tgataaatac
    20521 atattatttg aatcttgtat aatttgtgtt atctcattct gattgttcct aattgataat
    20581 ccagtttcca taaaattttc cttcctttaa tttaaagata gtatttattt tttcaaattc
    20641 agtaatgtga ctactaaaat tttcagtaac atcaaatata gttaatgatg tagttccctc
    20701 ctgaaaattc ttaaatactt ttatttcagc aagatcttta ccaatataat gtttcggtat
    20761 ataaaattta ttaatatctt ctaaaatata cgtactacta tattttgtat aatttcagtt
    20821 gatttcatca atcaaataaa atacttcatc actcattcat cactttaaaa agttgatgtc
    20881 tcaccacatt agaaagctta acactacttt tttatttgtt attatatgtt tatttctttc
    20941 aggggaaggg atatatatct ggtttcactc tatatatttt ccagccaaag atatctcttc
    21001 cggacaattt gcttgtggca actatctcat aaccatcttc ttacagaaga aaaccacttc
    21061 tgttcttcgg aaatcgcgcc atttaggaat ggaggatata agccacaagt gatcaaaaat
    21121 ttctatattt aatgtgacaa tcaagattta atatacccag attttcgact actgtcttta
    21181 tttgcatata aatgctccat aatatcctga tattctccga ttttcatatt aaaattggaa
    21241 atattgacct ctgcaattaa ttgtaataac gcactgtcat gtgctacttc ttctgttaat
    21301 tcttgactgg acagataacg acttcgttca atcatgctta tctcctccct actaccttac
    21361 tgaataattt actcattaat aaaataatgg aacaactcat aaggaaccga ttctcgtaag
    21421 gccaagtcca ttgtaacaat attttggcca ttaactcgtt cctgctgagg cgtgccggca
    21481 attacatcca cttgccctaa ataataatga tccggatcat ctaagtcact cttcttaata
    21541 aataaatgta aatcaattcc ctgctcttgg tgctcaataa ttttacgctc tgtttttgat
    21601 tgcaaggtac gtcgcgatgt ggtgaaccat ttaagaatat tctgattgat gaattcatct
    21661 tcatattgaa tctctgcatt agtcttatcc gtcttgtgat agttaacaaa aataggcacc
    21721 atttgattat ttaaagaata cccaaacata gtagatgttc cgtcactgtc ccaacacatc
    21781 aaacgtgaaa catcttttcg tgaatatttt tgacctattt taagtggtga tgttgtgtaa
    21841 cctgctggga agtcagctga attcatcagc ccgacttcaa tggcatccac cattaattca
    21901 gtaaaccacg cattatctgc caataattgc ttgagttgat tatttaatgt atagctatct
    21961 gaagtcacaa caaaccaatc tccaccatat tttttctgat cagttgattt aaaaaaatga
    22021 agttccagta cgttctccac cgattctaaa atggcttgat tataagcaac attataattc
    22081 tccaactcta tgcaataagc ttctttttca actgcttggt cctgatctat caacattttc
    22141 attaagatta attcgtgtgg ccgcttcccg ttcatcaatt cctttgtcac aaaatataaa
    22201 acttggcccg caaattcttt gtaagaaaac ccataagtcc tttctttttc catataggca
    22261 ataaattcac tatgatttct gaagcgcgta tcaaaaataa cttgcggttc cattgactga
    22321 tgaatgacaa aatctttcaa cattggaatt cgaccaatcc gttgcttcaa atcagcataa
    22381 gcttttttca agttagccat gctagataat tttgtgttct gaatcgaatc aaaaatttgt
    22441 ttcttagcaa tttcttcaaa gttgactgtc gtaattccgt caatttggtt acgattggct
    22501 aaatcttttc ggtaattatc tttattgtat gactgatctc caaacagcgc catgggaatc
    22561 atgtaattat ttttataatt cccaataaaa tcaattacag taacaaactc tttatcggga
    22621 tacttacgca aaccacgtcc cag
//
