LOCUS       NZ_CP040414            22745 bp    DNA     circular CON 23-APR-2024
DEFINITION  Dolosigranulum pigrum strain KPL3090 chromosome, complete genome.
ACCESSION   NZ_CP040414
VERSION     NZ_CP040414.1
KEYWORDS    RefSeq.
SOURCE      Dolosigranulum pigrum
  ORGANISM  Dolosigranulum pigrum
            Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
            Dolosigranulum.
REFERENCE   1  (bases 1 to 2009643)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Eslami,S.M., Gao,W., Bomar,L., Fernandez Escapa,I., Roberts,R.J.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     The nasal commensal Dolosigranulum pigrum exhibits stable synteny
            and highly similar strain circulation over a 20-year span
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2009643)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2019) Microbiology, Forsyth Institute, 245 First
            Street, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-AUG-2018
            Assembly Method                   :: HGAP v. 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 423x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017655685.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 02:23:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,936
            CDSs (total)                      :: 1,864
            Genes (coding)                    :: 1,836
            CDSs (with protein)               :: 1,836
            Genes (RNA)                       :: 72
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 28
            CDSs (without protein)            :: 28
            Pseudo Genes (ambiguous residues) :: 0 of 28
            Pseudo Genes (frameshifted)       :: 9 of 28
            Pseudo Genes (incomplete)         :: 15 of 28
            Pseudo Genes (internal stop)      :: 6 of 28
            Pseudo Genes (multiple problems)  :: 2 of 28
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:01:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1231710
            Orig. end                         :: 1254455
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040414.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22745
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="4"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22745
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22745
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12745](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12745)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    173..187
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.96"
                     /tool="antismash"
     misc_feature    552..570
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.17"
                     /tool="antismash"
     misc_feature    553..569
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.78"
                     /tool="antismash"
     gene            1054..2175
                     /gene="alr"
                     /locus_tag="FE331_RS05830"
                     /old_locus_tag="FE331_05800"
     CDS             1054..2175
                     /EC_number="5.1.1.1"
                     /GO_function="GO:0008784 - alanine racemase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="alr"
                     /inference="COORDINATES: protein motif:HMM:TIGR00492.1"
                     /locus_tag="FE331_RS05830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05800"
                     /product="alanine racemase"
                     /protein_id="WP_208967420.1"
                     /transl_table=11
                     /translation="MKRETYAEINLSNLAHNIHSFKQLLSSDTAITSVIKANGYGHGAV
                     TIAKELTELGINRFAVALGQEGIELREAGLADSSILIFTPIDEANVAEAIRNQLTMTIF
                     TPAQATIISQQARELQLPATVHLKVDTGMARLGVRSLEEAEATLEALDTEWITVEGIYT
                     HFANGDDLDHPEYTHQQFNAFRDIFEALEEQGYRFTFKHCCNSSATIRFPDYHLDMVRI
                     GLGMYGYNTDSSMDGMLDIRPIMTIKSHIAHVKTVPANTPVSYGWSHYTKEPTKIATLA
                     LGYADGVPRSLSNGGQFKVRGQIVPIIGRVCMDQLMLDVSDVEEVAVGDTVLWFGDETI
                     GGLNLEDTCNMSNHYHYEVLCNLNQRLPRIYHS"
     gene            complement(2231..2473)
                     /locus_tag="FE331_RS05835"
                     /old_locus_tag="FE331_05805"
     CDS             complement(2231..2473)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635910.1"
                     /locus_tag="FE331_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05805"
                     /product="hypothetical protein"
                     /protein_id="WP_111951929.1"
                     /transl_table=11
                     /translation="MKKLSKFLTVVLAAGTLAACSNGAKDTAEEPAVDEPAVEETVKDP
                     AADDATTDPAADDATDPAADDATDPAADDAADDNQ"
     gene            complement(2515..2742)
                     /locus_tag="FE331_RS05840"
                     /old_locus_tag="FE331_05810"
     CDS             complement(2515..2742)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635910.1"
                     /locus_tag="FE331_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05810"
                     /product="hypothetical protein"
                     /protein_id="WP_208967421.1"
                     /transl_table=11
                     /translation="MKKLSKFLTVVLAAGTLAACSNGANDAAEEPAVDEPAVEETVEDP
                     AADETVDPAEDSAADDATDPAADDAADDKQ"
     CDS_motif       complement(2701..2742)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKLSKFLTVVLAA"
                     /locus_tag="FE331_RS05840_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2515..2700)
                     /prepeptide="core"
                     /locus_tag="FE331_RS05840_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.90"
                     /molecular_weight="5922.8"
                     /monoisotopic_mass="5919.5"
                     /core_sequence="GTLAACSNGANDAAEEPAVDEPAVEETVEDPAADETVDPAEDS
                     AADDATDPAADDAADDKQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKLSKFLTVVLAA"
                     /leader_location="[2700:2742](-)"
                     /alternative_weights="5940.9"
                     /alternative_weights="5958.9"
                     /alternative_weights="5976.9"
                     /alternative_weights="5994.9"
                     /alternative_weights="6012.9"
     gene            complement(2793..3041)
                     /locus_tag="FE331_RS05845"
                     /old_locus_tag="FE331_05815"
     CDS             complement(2793..3041)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635908.1"
                     /locus_tag="FE331_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05815"
                     /product="hypothetical protein"
                     /protein_id="WP_208959106.1"
                     /transl_table=11
                     /translation="MKKLSKFLTVVLAAGTLAACSNGANDAADDTKVDEPAVEETVEDP
                     AADDAMDDKADPTDEKTDADTEATEDSNGEENADDKQ"
     misc_feature    3571..3589
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.95"
                     /tool="antismash"
     gene            3572..4213
                     /locus_tag="FE331_RS05850"
                     /old_locus_tag="FE331_05820"
     CDS             3572..4213
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012415.4"
                     /locus_tag="FE331_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05820"
                     /product="CAP domain-containing protein"
                     /protein_id="WP_208967422.1"
                     /transl_table=11
                     /translation="MRIIRKLFTAILFILFGYWLALSNVLAGSKIEHGIQQVMDVLPIT
                     SDTWDQPAHTKTNIQTTLINTLSDSSEEDFDFYTIQQDIIKKTNELRAELGAGELIEQA
                     SLDTGALIRAQETMTSFSHTRPNGQSPFSVFTDSAEAPNYNYTVIGENLGMATHHRLNQ
                     AEVTDLIFNGWVDSPGHYENMINPNFTEIGVGVASDGEAIYITQLFGRPQ"
     gene            complement(4305..5945)
                     /gene="groL"
                     /locus_tag="FE331_RS05855"
                     /old_locus_tag="FE331_05825"
     CDS             complement(4305..5945)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="groL"
                     /gene_functions="other (smcogs) SMCOG1299: chaperonin
                     GroEL"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003778456.1"
                     /locus_tag="FE331_RS05855"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05825"
                     /product="chaperonin GroEL"
                     /protein_id="WP_004635906.1"
                     /transl_table=11
                     /translation="MAKEIKFAEDARQAMLRGVDKLADTVKVTLGPKGRNVILDQSYGA
                     PQITNDGVTIAREIELEDKFENMGAQLVVEVASKTNDIAGDGTTTATVLAQAIVNEGMK
                     NVAAGANPVGIRRGIETATNRAVEALRNLSTDVSDNESIEQIAAISSGDAEVGKFIADA
                     MDRVGSDGVITIEESRGIETELDVVEGMQFERGYLSQYMVTDNEKMEANLDNPYILITD
                     KKISNVQDILPLLENIMQQNRPLLIIADDIDGEALPTLVLNKIRGTLDVTAVKAPGFGD
                     RRKGMLEDIAILTGGTVITEDLGLELSDATINDLGVAGKAVITKDDTTIVEGSGDKAQI
                     EERVQLLKKQADETESSYDQEKLQERIAKLVGGVAVIKVGAPTETEIKERKLRIEDALN
                     ASRAAVAEGIVAGGGTAYINILDQLRDIEAEGDEKTGVNIVVRALEEPVRQIAKNSGQD
                     GSVIVERLKQVDEGVGFDAVTGEMVNMVEAGIIDPTRVTRSALQNAASVAALLLTSEAA
                     VADLPSDDDGGQPGGMNPGMGMGGMGGMM"
     gene            complement(5980..6267)
                     /gene="groES"
                     /locus_tag="FE331_RS05860"
                     /old_locus_tag="FE331_05830"
     CDS             complement(5980..6267)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="groES"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635905.1"
                     /locus_tag="FE331_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05830"
                     /product="co-chaperone GroES"
                     /protein_id="WP_111950130.1"
                     /transl_table=11
                     /translation="MLKPLGNRVLLEVIKEEQKTQSGFVLPESAKDKPQTARVVAVGQG
                     RLLDSGQRSEPIVAENDTVVFEKYAGTEVKDQGKDYLIVSESDIIAIVEG"
     misc_feature    complement(6369..6380)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.13"
                     /tool="antismash"
     gene            complement(6601..6750)
                     /locus_tag="FE331_RS05865"
     CDS             complement(6601..6750)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE331_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_208953078.1"
                     /transl_table=11
                     /translation="MKQQTCQQEKQHKNMQKNQHNQTEEERALRLLKQQITDNIDIFIR
                     LRDK"
     CDS             6858..7070
                     /gene="allorf_1238568_1238780"
                     /locus_tag="allorf_1238568_1238780"
                     /protein_id="allorf_1238568_1238780"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGAVQDMVMFSSTKNLSTHTIILRRSFDLLGYFVAFHAIFGISIY
                     ANQFIYGKIGVGHCGLSPILLRGLI"
     CDS_motif       6858..6890
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGAVQDMVMFS"
                     /locus_tag="allorf_1238568_1238780_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6891..7070
                     /prepeptide="core"
                     /locus_tag="allorf_1238568_1238780_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="6380.5"
                     /monoisotopic_mass="6376.6"
                     /core_sequence="STKNLSTHTIILRRSFDLLGYFVAFHAIFGISIYANQFIYGKI
                     GVGHCGLSPILLRGLI"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGAVQDMVMFS"
                     /leader_location="[6857:6890](+)"
                     /alternative_weights="6398.5"
                     /alternative_weights="6416.5"
                     /alternative_weights="6434.5"
                     /alternative_weights="6452.6"
                     /alternative_weights="6470.6"
                     /alternative_weights="6488.6"
                     /alternative_weights="6506.6"
     gene            complement(7181..7876)
                     /locus_tag="FE331_RS05870"
                     /old_locus_tag="FE331_05835"
     CDS             complement(7181..7876)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015325.4"
                     /locus_tag="FE331_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05835"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_208967423.1"
                     /transl_table=11
                     /translation="MNVFIYYGNDLNKSSGSNIFVNKLINSAKKFVKDGKVYLRHGGDM
                     KLEYISNWKDVMNFDTKLDKQQIANEIYDSSIIILISPVFIHNVSSFMKIFLDNFAVWT
                     HIAPLVGKVGLPISISSTNGNVFVNNYLTKIMNYWGLVTCEPVSLELGLMTEDALDSYI
                     RQIIQTMEEIDTGGINFDTTQVEYFFDYILKTMSTYQKNHPEKILFDQLPYSNCQTFRE
                     AFEMMRERY"
     gene            complement(7879..9996)
                     /locus_tag="FE331_RS05875"
                     /old_locus_tag="FE331_05840"
     CDS             complement(7879..9996)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="FE331_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05840"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_208967424.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.6e-19, bitscore:
                     66.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKRIKLINQTSYTECGQCCISMIANFYGFRQPISYYKSIYSTGR
                     DGMNVSQVYSILADIHLTPDPYYLNEVSSFDFSNRPYILLTNNNHYIVLKKIADKKFRI
                     WDPAKGVKNVSKERISCINGGIIFEVYPDDDFCCVNNQDNIFKYLINFVKKVKYDLMRV
                     FIISTATYLISAGIPRLLEYIISTLLKENNSTILTHNIFKVVSLSFIYFLFSHFENKMI
                     LKLQKNINQEITLETIEHVLNIPYTFFENRGENNIIYRLGLLPKLMDLIANRFVNLLIG
                     TIGIVVLSIYSIIRYNILLPIILVMIIVPTCMILSFNYYIMNKKQDELAREAESEEEQI
                     DLIKNIFYIKTSRIADKVFVRYKKIYGSYLDIFIKNSNSGYFFNLVLTIYSIFSPIFIV
                     LYIGYFYEVTAGEIFFIYSIIGMILTNTISTITILGEMGLLRPTLVYLNDIYDEKKEHK
                     PEGILISEFENFHVKNLSFKYTDSGPDILNNITMKINRGEKISLVGLSGSGKTTLIKLI
                     TGIYNTYSGKILINGKNITCVNSHFFENKVAIVSQSTTLFNRTVKENIFVEKNHTDDNT
                     IWKVLKMVNLDDYIKGLPLQLNTMVGEDGLNFSGGQLQRLILARALIKNPELIILDEAT
                     SSLDTYNETLIYNNLKNLGMTILSISHRLDTIKDSDRIYVMDNGKIVAVGNHDSLLESN
                     YMYNQMYNLGG"
     gene            complement(10001..12745)
                     /gene="lanM"
                     /locus_tag="FE331_RS05880"
                     /old_locus_tag="FE331_05845"
     CDS             complement(10001..12745)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="FE331_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05845"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_208967425.1"
                     /sec_met_domain="DUF4135 (E-value: 6.8e-68, bitscore:
                     226.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.6e-33, bitscore:
                     112.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEKLSTVIETISIEEITHYFICDEKINYLTDIHNYDFKNILREI
                     NNDVYPIIETIIVDMYHTLKESGELEGDSLQKDFKQLTVILEREKRIDRLFDQYPCAKT
                     IIRKLIFDIVNELTEIFDRFEKDKNELSILLNDDLKMIKNIELSQGDRHDNRTVAKVTF
                     SNNRALFYKPRNLKTDLIYNDYLSFYEQHSNIVFKKLKVLTRCAYAWQEAAEINQNLSL
                     DEAKEYYYRAGFLLALFTIFRGTDIHFENIIVSDLCPVIIDSETMFSSAHFENLKTNNG
                     KSINQSVLGTAMLPFKDQLYDINISGLFPKSEISKQLKVEILIEDETQGLKYESMAITS
                     EIFPNAVLVDNKIIDYKLVMSDLEKGVREGLEIIANNKEHFLRIIQKYDSKCIKIRKLL
                     RGTQVYYTFLNELKKPTALSDERVRDKILRILSKNFSPTNFGYLRVENEIFDLKQMNIP
                     YFYTYLKDNDLYSRDKVICKNYHNITAWDNMKHAIEQLDQNMIDYQIHLLNLSLTVDNF
                     SEDDINGSFNGEINKGENIYKDLYPYELLKREVIIEDEKRSYIYMLGFNEKNLKITIND
                     PGLYMGGGVLHYLGSYAYTQNDDEIKDFCKRMINQLFDQYQEQSSNGEKISYNVYQGFG
                     GLVYICYNFYQYFDDEEIKNYTEKISKGMVNYLENSNRTNSDFDYINGDLSLIVLLIKL
                     FSETTLRITNRKTMKSILRKYHELLRGENISEIGLAHGLSGVILTLSYMYKITEDKDIL
                     KFMYELVEKEDCLIDENTIDGSWCRGVGGILISRYTSLDNIKNSSDKKLKQKLQKTINK
                     LNQKEYVDVFLDTNNICLCHGFAGTIDILAYISKISKNNHIEELKQLYIDGHDIKRFEW
                     FKGSNYVLESFMLGVTGSLYSLLHKQFDIPSVSGLNLFFKKSR"
     gene            complement(12763..13353)
                     /locus_tag="FE331_RS05885"
                     /old_locus_tag="FE331_05850"
     CDS             complement(12763..13353)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE331_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE331_05850"
                     /product="hypothetical protein"
                     /protein_id="WP_208967426.1"
                     /transl_table=11
                     /translation="MMRGLCYYYTQESKKRTTVALLIGLIVLATSLLEGIPEIMLFYFT
                     IVSTNIYSSNQALIKQRYYLEHIVPINYSTIIIFKYTALLIKVLVSILMYGMLLKYVFK
                     EDERIVLQLLLLFSVAINLGSVTILRELSYNQLDKWKGIILQFFIVLLPFILEYGIKTS
                     AICSGDQIIQIINAIVAVIICVVTAKMIRFVSN"
     gene            complement(13366..14010)
                     /locus_tag="FE331_RS05890"
                     /old_locus_tag="FE331_05855"
     CDS             complement(13366..14010)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024741.4"
                     /locus_tag="FE331_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05855"
                     /product="ABC-2 transporter permease"
                     /protein_id="WP_208967427.1"
                     /transl_table=11
                     /translation="MISIIRKDIMSSGLKLQTIYAVILSVLSIMLFFDIVQYLVIVAYG
                     IIIIAPLAYFGSVFNYTTLDYHKEELMLPVKRPDIVTARYVNYLFLTGTNFMLVLGFIW
                     LYESNVTLLEASMKSAIFLTMAVGLHFGSIVLGGAFLFGHKHIKTIILASFLLTIVPVR
                     LLMEGIKIIMKLDGTFDAYNYPILMILFIGGSILLYGLSFGVSLISFNQKF"
     gene            complement(14007..14876)
                     /locus_tag="FE331_RS05895"
                     /old_locus_tag="FE331_05860"
     CDS             complement(14007..14876)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="FE331_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05860"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_208967428.1"
                     /transl_table=11
                     /translation="MSNAVEIKQLNVHYKNSEFSLDDVTINIPKGYIVGLIGENGAGKT
                     TIINSILGLQKQYTGVVEIFGETMDLDNTELKEKIGVCFDEIYLPKNLKIKQVEDIYRK
                     FYPRWDSNFFNQTLDFFNISQYKKIEECSQGMQKMFSIVLSMSHQPDFLVLDEPTSSLD
                     PVKRQDVLEIFQTYIAEDEKRSILFSSHITTDIEQIADIVIFLKAGQVVFCEPITTLLY
                     DYGMCHCTKEQFDQLHQTSMIAYKKETYGYSVLLNRKQIDNELPDYIEVEKPNLEFIMN
                     MYAKGVIV"
     gene            complement(14869..15243)
                     /locus_tag="FE331_RS05900"
                     /old_locus_tag="FE331_05865"
     CDS             complement(14869..15243)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012610.4"
                     /locus_tag="FE331_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05865"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_244359330.1"
                     /transl_table=11
                     /translation="MIINVQSKEPIYEQIVLQIKSKIKNGELTAGDSLPAIRTLAKDLK
                     VSVITVKKAYEILQTDGLIMSVVGRGTVIADVKREMITKNIEQDVEIKIKELMSYSQKQ
                     GMNKRELINLFKRVVGDIDE"
     gene            complement(15363..15578)
                     /locus_tag="FE331_RS05905"
                     /old_locus_tag="FE331_05870"
     CDS             complement(15363..15578)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE331_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE331_05870"
                     /product="hypothetical protein"
                     /protein_id="WP_208967429.1"
                     /transl_table=11
                     /translation="MNKNSRIDFKELERLSKFGGADNGADNFGQDRAVTPVVSASLKFC
                     APAISAVTTFLSCNRSCGWGCKKKKK"
     CDS_motif       complement(15519..15578)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNKNSRIDFKELERLSKFGG"
                     /locus_tag="FE331_RS05905_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15363..15518)
                     /prepeptide="core"
                     /locus_tag="FE331_RS05905_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.00"
                     /molecular_weight="5205.9"
                     /monoisotopic_mass="5202.7"
                     /core_sequence="ADNGADNFGQDRAVTPVVSASLKFCAPAISAVTTFLSCNRSCG
                     WGCKKKKK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNKNSRIDFKELERLSKFGG"
                     /leader_location="[15518:15578](-)"
                     /alternative_weights="5224.0"
                     /alternative_weights="5242.0"
                     /alternative_weights="5260.0"
                     /alternative_weights="5278.0"
     gene            complement(15775..16902)
                     /locus_tag="FE331_RS05910"
                     /old_locus_tag="FE331_05875"
     CDS             complement(15775..16902)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635904.1"
                     /locus_tag="FE331_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05875"
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="WP_208967430.1"
                     /transl_table=11
                     /translation="MNQFNLLATCASGVEGLVGDELRDLGYEVEVENGRARFLGRKHDI
                     ARANLWLRIADRVKIIIGEFEARDFDSLFEQTKALPWEDYIPLDGAFPVAGKSQKSKLY
                     SVPDVQRIVNKAVATRLQEAYHKRGRLPESGATYPLEVAINKDKVLITLDTTGDSLFKR
                     GYRTGKGDAPLKENLAAALIALTTWFPDKPFVDPTCGSGTIPIEAALIGHNIAPGFNRS
                     FLCEAWSWMPAELWQTVRQEADEAANYDVELDISGFDIDHKMIEIAKENAMEAGLLHSI
                     NFKQMQVADFTTDKRYGVMISNPPYGKRIGDQAAVEKLYRQLGDVWRPLETWSKYIITD
                     DLDFEKHFGQKATKRRKLYNGYLRTDYFQFWGKRS"
     gene            complement(17088..17744)
                     /locus_tag="FE331_RS05915"
                     /old_locus_tag="FE331_05880"
     CDS             complement(17088..17744)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF036878.4"
                     /locus_tag="FE331_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05880"
                     /product="PIN domain-containing protein"
                     /protein_id="WP_146737474.1"
                     /transl_table=11
                     /translation="MNFIQRMVHKPKSITLVDYENISKKFISYCEELTKRDYCFVFYSK
                     ADNTMQFEKVNELLQLDCKVEFIQVINGSANALDFQMSSYLGYFLQEFPKSQFVLLSND
                     KGFDPVVKHWITKGYNVRQDFLSLRNDSPKSSSAYHKPAPTPKQPKHHPQKTRLDQVIY
                     NIVGSNVKPADRSKVKGIFYASQSKDELRHKLCDAFGPDRGSSYYKYLRDQMDHK"
     ncRNA           complement(17850..18213)
                     /db_xref="RFAM:RF00011"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="FE331_RS05920"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="FE331_05885"
                     /product="RNase P RNA component class B"
     gene            complement(17850..18213)
                     /gene="rnpB"
                     /locus_tag="FE331_RS05920"
                     /old_locus_tag="FE331_05885"
     gene            complement(18257..18592)
                     /gene="gpsB"
                     /locus_tag="FE331_RS05925"
                     /old_locus_tag="FE331_05890"
     CDS             complement(18257..18592)
                     /codon_start=1
                     /gene="gpsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030917.1"
                     /locus_tag="FE331_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05890"
                     /product="cell division regulator GpsB"
                     /protein_id="WP_004635902.1"
                     /transl_table=11
                     /translation="MVNTELNQKQIFEKEFSKSMRGYNPEEVDEFLDIIMRDYKVFDDK
                     IEDLKKEIASLEEQLAQKPAPQPQPAAPAEPKQPSSQMMATNIDILKRISNLEHHVFGA
                     KMENGDN"
     gene            complement(18676..19227)
                     /locus_tag="FE331_RS05930"
                     /old_locus_tag="FE331_05895"
     CDS             complement(18676..19227)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635901.1"
                     /locus_tag="FE331_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05895"
                     /product="SLOG family protein"
                     /protein_id="WP_208967431.1"
                     /transl_table=11
                     /translation="MIKRLFVSGYRSYELGIFSEDDDKLFFVKEFLKASLSQYIQNGLE
                     WVITSGQLGIELWTAEVVEELREEYPNLQLVLLLPYQEYGNSWNEKNQLLLQKAIEQAD
                     YMNYTSHEPYKHGGQLSGNAQFILNNTDGLLLIYDNEYEGKSSYLYEQVKAHQEVHDYL
                     LDQIYMDDLQSFVADYQERN"
     misc_feature    complement(19219..19232)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.71"
                     /tool="antismash"
     gene            19303..19917
                     /gene="recU"
                     /locus_tag="FE331_RS05935"
                     /old_locus_tag="FE331_05900"
     CDS             19303..19917
                     /EC_number="3.1.21.10"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="recU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635900.1"
                     /locus_tag="FE331_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05900"
                     /product="Holliday junction resolvase RecU"
                     /protein_id="WP_077862537.1"
                     /transl_table=11
                     /translation="MVNYPNGEPYHSKHDKKRRHLQVKPKTMTYSNRGMTLERMINASI
                     KYYRETGQAVLHKKPTPVQIVNVDYPRRSAAKITEAYFKRASTTDYNGVYRGYYLDFEA
                     KETKNKTSFPLSNFHEHQIRHMQHCLEQGGIVFVLVYFSHLRQLYLLDAQYFIDYWEDH
                     LAGGRKSIPLTIFEAEGYPISLGYAPQIPFLQAVDEFISTM"
     gene            19951..22302
                     /locus_tag="FE331_RS05940"
                     /old_locus_tag="FE331_05905"
     CDS             19951..22302
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635899.1"
                     /locus_tag="FE331_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE331_05905"
                     /product="transglycosylase domain-containing protein"
                     /protein_id="WP_208967432.1"
                     /transl_table=11
                     /translation="MSDNNYSRQSRKQKKNHQKKSKRKVTHTSAVNLWLKRGLLVIFAA
                     IMLVLISGGGLFLYHAQGAPELTDDDLYGAYYSSLVDKDGHEFYRLGTDSREFASAEEY
                     PELLTDAVKSIEDQRFDSHNGFDFIGIGRAAVDYLRAGEIVSGGSTITQQLVKLSVFST
                     LREDQTIERKSQEIWLSMQLERRLSKEQIMTLYLNKVHMAGNVYGMGTAAKEYYGKHVS
                     ELELHEAALFAGMPQSPNSYNPYTEPERAKQRRDEVLVAMYNNDKITKEQMEQAQAIPI
                     EQGLQEKVEQTDEDTLLFDSYLSAVLDEVYEKTDFDPYKAGLEIHTNYDSSVQQILHDV
                     AHSEDYISIDSDIQTAISVVNPNNGEILGILGGRNLQGQLSYNRATKNRRNVGSTIKPI
                     TSYGPAIEYNQYSTHEQIVDEPYSPAGSNWNFNNYDNQYLGQMSMREALVQSRNIPAAK
                     IMNDYMNIENVEAFVSKLGLDPKEISGANGLVPSNSIDGSMTPLQLAGAYSAFANEGIY
                     TEPHTVNKVVTQRGQEIDMTPESTRAMEDYTAYMMTDMLKGVPEARPEINVPGIYHAGK
                     TGTTNFTDEQFEEYNLPRGMGLIPDSWYVGYTQDFVISTWVGYDEPFKEGNQLIFGDTT
                     HNLPLYYYSAIMNQLAQTTENTDWIKPDSVSEVNVVSGSSPAQLPNRSTPFSSITTELF
                     VAGTEPQSVAPAPVQPQPTEPQVTDEDEKDKEDSEEDNKDNNEQNPTDPIDEEGSGQQP
                     GTQPNDPNDQNSQGAQEPQTSGSGGAGGNN"
     gene            complement(22407..22658)
                     /locus_tag="FE331_RS05945"
                     /old_locus_tag="FE331_05910"
     CDS             complement(22407..22658)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE331_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE331_05910"
                     /product="hypothetical protein"
                     /protein_id="WP_112790136.1"
                     /transl_table=11
                     /translation="MKRNNGTILFVMGLVIVALGVYLTQYDTIMGVLAAGVGLFTVINS
                     FNVRKGEDSPVNRWAKKRHDKELEKLREEEKQKNTGRK"
ORIGIN
        1 cgtcattccc ccatgctcat caataataat tgccatatga tttttattgc gttgcatcaa
       61 ccgtaataaa tctgacaatt tcataacagg aggcacgaac aagacttctg ataacaaact
      121 aacaatcgac gttgcgtgaa ctttttgttg tgacttagct ttcaaatatc ggtggaagtc
      181 tttttcatgc aagacaccaa tcacattatc taccgtctct tcataaatca caagccgtga
      241 aaacggacta tgctcaaaaa tatcttctat cttctcatcc ggatcatcaa tctccgctcc
      301 aacgacatca atccgtggcg ttaagattga agaaacattc acatcatcga attcaatcgc
      361 tgccttgacg agtaaatgtt catcatgctc aatacttcct tccacccgag cttcttccac
      421 gaatgataac aattccgctt cactaatcgt atatgccgaa tctaccggaa taaatcgctt
      481 aaccaaattt tgccacttat tcaataacca gataaatggt ttcaacacta acatcaacgc
      541 acttaacacc ggttgcgaaa acatcgcaac tttctcagga gctaattttg ccaataactt
      601 cggggcaatc tccccgaaga ataataacaa taaggtggtg acaatcgtag caatcgcccc
      661 accatatgtc ggaaaaatag ccacaaaaaa tatagtcgct actgccgaac cagcaatatt
      721 gactaaatta ttcccgatca aaatggtaga caacaacgat tcaaactgtt gctgtaactt
      781 caacgtcttc tccgctcgct tatcaccatc ttcactttta ttttttaaac gaacagcttg
      841 ggctgaagtg aaagctgtct cactagaaga aaaaaaggcg gataaaataa tacaaataat
      901 aaaaattaaa atactataaa actgacttga ctccatgact ggataactcc tccttgtacg
      961 cagttcccca taagtatacc ataaattttt agacaaaacg atagtgtttt tctcacacaa
     1021 gagtgatata atacagtcat gagaggtgat tcaatgaaac gagaaacata tgctgagata
     1081 aacctaagca acttagctca taatattcat tcatttaaac aattattatc aagtgacacg
     1141 gctattacca gtgttattaa agcaaatgga tatggccatg gtgctgttac gattgccaaa
     1201 gaattaactg aacttggtat taaccgattc gcggtagcat taggacaaga agggatagaa
     1261 ttacgtgaag ctggcttagc cgatagttcc attcttattt ttacgcctat tgatgaagcc
     1321 aatgttgctg aagccattcg taatcagcta acgatgacca tctttactcc agcgcaagca
     1381 actattattt cgcaacaagc tcgcgaatta caacttccag cgacagtcca cttaaaagta
     1441 gatacaggaa tggctcgact tggtgtgcgt tccttagaag aggccgaagc tacccttgaa
     1501 gcactcgaca cagagtggat aactgttgaa ggaatttata cgcacttcgc taatggcgat
     1561 gatcttgatc atccggaata tacccatcaa caattcaatg cttttcgcga catatttgaa
     1621 gccttagaag agcaaggcta tcgcttcaca ttcaagcatt gctgtaattc tagtgctacc
     1681 attcgcttcc ccgattatca tctagatatg gtgcgtattg ggctaggcat gtacgggtat
     1741 aacaccgatt cgagtatgga tggcatgcta gatattcgtc ctatcatgac cattaagtcg
     1801 catattgctc acgtaaaaac tgtgcctgct aatactccag taagctatgg ctggtctcat
     1861 tatacaaaag agccgaccaa gattgctaca cttgccctag gatatgctga tggtgtccct
     1921 agaagtctgt cgaacggcgg tcaatttaaa gtacgcggtc aaatcgtgcc cattattggt
     1981 cgggtctgca tggatcaact gatgttagat gtctctgatg tagaagaagt cgcagttggg
     2041 gatactgttt tatggtttgg tgatgaaaca attggtggct taaatctaga agatacctgt
     2101 aatatgtcga atcattatca ctatgaagtg ctgtgtaact taaatcagcg cctcccacga
     2161 atttatcata gttaatttta aaaaaagacc gtacggacat gtccgtacgg tctctttcta
     2221 cttaaattaa ttattgattg tcgtctgctg cgtcatccgc tgcagggtct gttgcgtcat
     2281 ctgctgctgg atctgttgca tcgtctgctg cagggtctgt agtagcgtca tctgctgctg
     2341 gatcttttac tgtttcttca acagctggct cgtctactgc tggttcttct gctgtatctt
     2401 ttgcaccatt actacatgct gcaagtgttc ctgctgctaa tacgactgtt aaaaacttag
     2461 ataatttttt catctgtatc tctcctttaa aaaataaatc ctatggttaa ttaattattg
     2521 tttgtcgtct gctgcgtcgt ccgctgcagg gtctgttgcg tcatctgctg ctgaatcttc
     2581 agcggggtct actgtttcgt ctgctgctgg atcttccact gtttcttcaa cagccggctc
     2641 gtctactgct ggttcctctg ctgcatcatt cgcaccatta ctacatgctg ctaacgttcc
     2701 tgctgctaat actacggtta aaaacttaga taattttttc atctgtatct ctccttaata
     2761 aaaaatgaat cctataattt agttaatttg aattattgtt tgtcgtctgc gttttcttcc
     2821 ccgttgctgt cttcagttgc ttcagtgtca gcgtctgttt tctcatctgt tgggtcagct
     2881 ttgtcatcca ttgcatcgtc tgctgctgga tcttccactg tttcctcaac agctggctcg
     2941 tctactttcg tatcgtctgc cgcatcgttc gcaccattac tacatgctgc caacgttcct
     3001 gctgctaata caactgttaa aaacttagat agctttttca tatatatctc tcctttttca
     3061 ttgccatata tccaatatat cattttttag gacttaatca agtcattacc tttgaaatca
     3121 ctcaatatgt ggtaattcta atatatattt aatgactttt ttgttttagt tgcttgatat
     3181 attgcttaat cactcataga tagagcgatt aatcattaag ttaattaagt cattgaatca
     3241 ttcccttaat gattataatt acatgttagc aagccttttc taaaaaatca agtcatatgg
     3301 ttcatataaa cattaccttt ttatgaattt tgtatgaatt tttcaatgct atctctagaa
     3361 taaatagtat cttcgtcatt tcatttatag agtaaaagca tgctcaatag ctcgaatatt
     3421 caatctgttc agtcccacca ccattacatc tttaattgta atagaaagga gttcataaac
     3481 ccttcattat ttatatctga ttctttcttc aaaagcttca ttagtcagca ttttttctga
     3541 tataatatga ggagcgaaag gacgatatct tatgagaata attcgcaaac tatttactgc
     3601 aattttattc attttgtttg gctattggtt agcgctatcc aatgtactag ctggctcaaa
     3661 aatagaacat ggcattcaac aagtcatgga tgttttacct ataacgtcag atacttggga
     3721 ccagccagca catacgaaga caaacataca aaccacttta atcaatacgc tatccgactc
     3781 atcggaagag gattttgatt tctacacgat ccaacaagac attatcaaaa aaacgaatga
     3841 acttcgggct gagcttggag ctggtgagtt aatcgaacaa gcctctctcg atacaggggc
     3901 acttattcga gctcaggaga cgatgacttc tttctcccac acgcgtccca atggtcaaag
     3961 tccattcagt gtcttcactg atagtgcaga agcaccgaac tataattata ccgtcatcgg
     4021 tgaaaactta ggcatggcca ctcaccatcg cttaaatcaa gcagaagtaa ctgaccttat
     4081 tttcaatggc tgggtagaca gtcccggtca ttacgaaaat atgattaatc ctaactttac
     4141 tgagattggt gttggcgtgg cttcagatgg ggaagcaatc tacattaccc aattattcgg
     4201 tcgaccacaa taattttttt acttgaaaag actccaactg aattatcagc tggagtcttt
     4261 tctttatcat tttaatcagt tgaatgaatg ggttggtgct gggcttacat catgccaccc
     4321 atgccgccca tacccatacc tgggttcatg ccacctggtt gacccccatc atcatcagac
     4381 ggtaagtcag ctactgctgc ttcagatgtt aacagcaagg cagctacact agccgcattt
     4441 tgaagtgctg aacgtgtcac acgtgttgga tcaataatac cggcttctac catattaacc
     4501 atttcaccgg ttaccgcatc gaagccaact ccttcatcca cttgtttcag acgttctaca
     4561 atgacgctac cgtcttgacc tgagtttttg gcaatttgac gaacaggttc ttctaaggca
     4621 cgaacaacaa tattcacccc tgttttttcg tctccttctg cttcaatatc acgtaattgg
     4681 tctaagatat tgatgtaagc tgttcctcca ccggcaacga ttccttctgc taccgctgct
     4741 cgtgaagcgt tcaacgcatc ttcaatacgc aatttacgtt ctttaatttc agtttccgtt
     4801 ggggcaccca ctttaataac cgctacacca cccacaagct tggcgatacg ttcttgcaat
     4861 ttctcttgat catagctaga ttctgtctca tctgcttgtt tcttgagtaa ttgaacgcgc
     4921 tcttctattt gcgctttgtc cccagatcct tctacaatcg tcgtgtcatc tttggtaata
     4981 accgcttttc cagcgacacc taagtcatta atagtcgcat cagataactc taaaccgaga
     5041 tcctctgtga tgaccgttcc gcctgttaga atcgcaatat cttctaacat ccctttacga
     5101 cgatcaccaa atccaggtgc tttaactgct gtaacgtcta aagtaccgcg gattttgttc
     5161 aagactaagg ttggaagagc ttctccatca atatcatcag caataattaa gagtggtcgg
     5221 ttttgttgca taatattttc taataagggt aagatgtctt gtacgttaga aatcttcttg
     5281 tccgtaatta gaatgtacgg attatctaag ttggcttcca tcttctcatt gtctgttacc
     5341 atgtattgtg acaagtaacc acgctcgaac tgcatccctt caacaacatc tagttcagtc
     5401 tcgattccac gtgattcttc aatagtgatg acaccatcgc ttccgacacg atccattgca
     5461 tccgcaatga atttacctac ttcagcatca cccgatgata tcgcagcaat ttgctcgatt
     5521 gactcattat cactcacatc agttgataag ttgcgcaacg cttcaacggc acgatttgta
     5581 gctgtttcga tcccacgacg aattccgact gggtttgcac cggcagcaac attcttcatt
     5641 ccttcattca cgatcgcttg tgctaggacc gtcgctgtag tcgttccatc tccagcaata
     5701 tcatttgttt tactggcaac ttctactact aattgcgccc ccatgttttc aaacttatct
     5761 tccaattcga tttcacgcgc aatcgttaca ccatcatttg taatttgtgg tgcaccgtat
     5821 gattggtcta gaatcacatt gcgtcctttg ggtcctaatg tcacttttac tgtatctgct
     5881 aatttatcga ctccgcgtaa catcgcttgt cgtgcatctt ctgcaaattt aatctctttt
     5941 gccataattt aaataaactc cttcctgatt aaacaaatat tatccttcaa caattgcaat
     6001 aatatctgat tcactaacga ttaaataatc ttttccttga tccttcactt ctgttcccgc
     6061 atatttttcg aagacaactg tatcattctc cgcaacaatc ggctcactgc gctgaccgct
     6121 atctaataag cgtccttggc ccaccgccac cacacgtgct gtttgtggct tatcttttgc
     6181 cgattctggc agtacaaaac cgctctgagt tttctgttct tctttaatca cttcgagcag
     6241 tacacgattt cctaaaggct ttaacataaa gttccctcca tttattaaat taattaattc
     6301 attatttaat tgatgggttt tagcactcac aggtatcgag tgccaactcc actaactatt
     6361 ataagcaaga taactttttc ttgcaagtca cacgcttttt ttaacggaaa aaattacaac
     6421 aataacgtaa acatcataat tcaaatttat ataaactaga actagtcaaa aaccccgaaa
     6481 agctgaaagc tcttcggagt ttttgggtat agaatagggt attgcagttc atttacttat
     6541 acagcataag tcggtacaat gcttgagttt atttccatca ttaaacatat atatttcatg
     6601 ctacttatct cttaatctta taaatatatc aatattatca gttatttgct gttttaatag
     6661 ccgcaatgca cgttcctctt cggtttggtt atgctgattt ttttgcatat ttttatgttg
     6721 tttttcttgt tggcaagtct gttgcttcat gatcaaaaca cctctttatc attttttatt
     6781 gcctctatat attaccttgc aattacgtcg ttttaaaaat tctatagtta ataacatttg
     6841 tactgccccc aaaaattttg ggggcagtac aagatatggt catgttctct agcaccaaga
     6901 acctctctac tcacaccatt attctgagga gatcgtttga tcttttgggc tattttgtag
     6961 cctttcatgc cattttcggc ataagcatct atgcaaacca gttcatttat ggtaagattg
     7021 gtgtgggtca ttgtggttta tcccctattc ttcttagagg gttgatatag gatgattgta
     7081 ccacagatga cccttttaaa tttctatttt aattttacaa tgaaggaaga acaatactaa
     7141 acatcttaat atgttgtaat caatctattt attaatggtt ctaatatctt tctctcatca
     7201 tctcaaatgc ttctctaaat gtttgacaat tagaatacgg tagttgatca aataaaattt
     7261 tttcgggatg attcttttga taagttgaca tagtttttaa tatataatca aaaaaatact
     7321 ctacctgtgt tgtatcaaaa ttaatacccc cggtatcaat ctcctccatt gtttgaatta
     7381 tttgcctaat ataactatcc aaagcatcct cagtcatcag ccctaattct agggatactg
     7441 gttcacatgt cactaatccc caataattca taattttagt tagataatta tttacaaaca
     7501 catttccatt tgttgatgaa atactaatcg gtaatcctac tttccccaca agaggtgcta
     7561 tatgagtcca gacagcgaaa ttatctaaaa aaatcttcat gaatgaggat acattgtgta
     7621 tgaaaactgg tgaaattaat atgataatac ttgaatcata tatttcatta gcaatctgtt
     7681 gtttatcaag cttagtatca aaattcataa catccttcca attagatata tactccagtt
     7741 tcatatctcc accatgtctt aaatacactt tcccatcctt aacaaatttt ttagcactat
     7801 ttattaactt gtttacaaag atattactcc cagaactttt atttaaatca tttccgtagt
     7861 atataaatac attcattttt aacctcctaa attgtacatt tggttataca tataattgct
     7921 ctctaacaac gagtcatgat ttcccacagc tactattttc ccattatcca taacatagat
     7981 tctatctgaa tcttttatag tgtctaatcg gtgagaaatt gacagtatcg tcatgcctag
     8041 attctttaaa ttattgtaaa ttaatgtttc attatacgta tctaacgaac ttgtagcctc
     8101 atccaaaata attaattcag gattttttat aagtgctcgc gctaaaatta acctttgtaa
     8161 ttgtcctcca gaaaaattca ggccatcttc tcctaccatt gtatttaatt gtaatggtaa
     8221 accctttata taatcatcaa gattcaccat ttttaatact ttccaaatag tattgtcatc
     8281 tgtatgattt ttttctacaa aaatattttc ttttacagtc ctattaaaaa gtgtcgtact
     8341 ttgtgataca atagccactt tattctcaaa aaaatgactg ttcacgcaag ttatattctt
     8401 tccattaatt aatatttttc cactatacgt attatatatt ccagtaatta atttaatcaa
     8461 tgtagttttt ccactcccag atagtcccac taacgaaatt ttttctccac gatttatttt
     8521 catagttata ttattaagta tatctggacc tgagtcagta tatttaaatg ataaattttt
     8581 tacatggaaa ttttcaaact cactaatcaa tataccttcg ggcttatgtt ccttcttttc
     8641 atcataaata tcatttaaat aaaccaaagt aggtctaagc aaacccattt cacctagtat
     8701 agtaattgtt gatattgtat ttgttaaaat catacctata attgaataaa taaaaaatat
     8761 ttctccagct gtaacttcat aaaaatatcc aatatacaaa actataaaaa ttggagaaaa
     8821 aatggaataa attgttagta ctaggttaaa aaaataacca ctattgctgt tttttataaa
     8881 tatatccaaa tacgatccat atattttttt gtatcttaca aataccttat cggctattct
     8941 tgaagtcttt atataaaata tattttttat taaatctatc tgttcttcct cactctctgc
     9001 ttctcttgct agctcatctt gttttttgtt cataatatag tagttaaaag ataatatcat
     9061 acaagtaggt actataatca taactaatat aatagggagc aaaatattat acctaattat
     9121 gctgtatatc gatagtacta ctattccaat agtgcctatc aataaattaa caaacctgtt
     9181 tgctattaaa tccatcaact tgggtaataa tcctaagcga tatattatat tattttctcc
     9241 acgattttca aaaaatgtat acggtatatt taatacatgt tctattgtct ctaaagtaat
     9301 ctcttgatta atatttttct gtaattttaa aatcatctta ttttcaaaat gagaaaacaa
     9361 gaaatatata aaacttaaac ttactacctt aaatatgttg tgtgttagaa tagtggaatt
     9421 attttccttt agtaatgtac taattatata ctctagtaaa cgtggaattc ctgctgaaat
     9481 taagtacgtt gctgtcgaaa ttataaaaac tctcatcaaa tcatatttta cttttttaac
     9541 aaaattaatt agatacttga aaatattatc ttgattattc acacaacaaa aatcgtcatc
     9601 tgggtatact tcgaaaatta tccccccgtt aatacaagag attctttctt tacttacatt
     9661 ttttactccc tttgcgggat cccaaattct aaatttttta tcagctatct tttttaaaac
     9721 tatatagtga ttattattag tcaacaagat atatggccta ttagaaaaat caaatgaact
     9781 tacttcattt aaataatatg gatctggtgt taaatgtata tcagctaata tagaataaac
     9841 ttgactgaca ttcataccat ctcggccagt actatatata cttttataat aagaaattgg
     9901 ttgtctaaac ccataaaaat tcgctatcat tgatatacag cattgtccac actcagtata
     9961 cgatgtttga ttaataagtt ttattctttt aaacatgtcc ttacctactt tttttaaaaa
    10021 ataaatttag ccctgatact gaaggtatat caaactgttt atgcaataaa ctatacaatg
    10081 atccggtcac tcctaacata aatgattcta gtacatagtt tgatccctta aaccattcaa
    10141 atcgtttgat atcatgtcca tcaatatata gctgtttcaa ttcttctatg tgattatttt
    10201 tcgatatctt acttatatat gctaatatat ctattgtccc tgcaaatcca tggcaaagac
    10261 atatattatt tgtatctaaa aaaacatcaa catactcttt ttgattaagt ttattaatag
    10321 ttttttgtaa tttttgtttt aattttttat ctgaactatt tttgatatta tctaaggatg
    10381 tatatcttga aataagtatt ccgccaactc ctctacacca actaccgtca attgtatttt
    10441 catcaattaa acaatcctct ttctctacta attcatacat aaatttcagt atatctttat
    10501 cttcagttat tttatacata tatgaaagtg ttagtataac acctgataat ccatgtgcta
    10561 aaccaatctc gcttatattt tcacctcgta ataattcatg atactttctc aaaatacttt
    10621 tcattgtttt tctattggtt attcgcaaag ttgtctctga aaacaatttt attaacagaa
    10681 caattagcga taaatctcca tttatatagt caaagtcact gttagttcta ttgctatttt
    10741 ctaaataatt aaccattcct ttagaaattt tttcagtata attttttatt tcttcgtcat
    10801 caaaatactg ataaaagttg taacatatat atactaatcc tccaaatcct tggtaaacat
    10861 tataggaaat tttttctcca ttactacttt gctcttgata ttgatcaaat agttggttaa
    10921 tcattctctt acaaaaatct ttaatttcat catcattttg tgtataagca tatgatccta
    10981 agtaatgcaa tacccctcct cccatatata atccaggatc attaatagtt atttttaaat
    11041 ttttttcatt aaatcctaac atatatatat aactacgctt ctcatcttca ataattacct
    11101 cccgctttaa tagctcgtat ggatataaat ccttatatat attttctccc ttatttatct
    11161 ctccgttaaa actaccattt atatcatctt ctgaaaaatt gtccaccgtc aagcttaaat
    11221 ttaataggtg tatttgatag tcaatcatat tttgatctaa ttgctcaatt gcatgtttca
    11281 tattatccca agctgttata ttatgataat tcttacaaat aactttatct ctagaatata
    11341 aatcattatc ttttagatac gtatagaaat atggaatgtt catttgcttt aaatcaaaaa
    11401 tttcattttc aactctcaaa taaccaaaat ttgttggaga aaaatttttt gataatattc
    11461 gcaaaatttt gtctcttact ctttcgtccg ataatgctgt tggttttttc aattcattca
    11521 aaaatgtata ataaacttgt gtccctcgta acaattttct tattttaata catttgctat
    11581 catatttttg tattatcctt agaaaatgtt ctttattatt agcaataatt tctaatccct
    11641 cacgtactcc tttttctaag tctgacatca ctaatttata atcaatgatt ttattatcta
    11701 ccaatacagc attgggaaat atttcgctag ttatagccat agattcatat ttcagtcctt
    11761 gagtctcatc ttcaattaaa atttccactt ttaactgttt agaaatttct gatttaggaa
    11821 acaaaccact tatattaata tcatataatt gatctttaaa tggtaacatt gcagttccta
    11881 aaacactctg attgatactt ttaccattat tagtttttag attttcaaag tgggcagatg
    11941 aaaacattgt ctcactatca ataattactg gacacaaatc actgacaata atattttcaa
    12001 agtgtatatc tgttccacga aaaatagtga ataatgctaa aagaaatcct gcccgataat
    12061 aatattcttt agcttcatct aaagatagat tttgatttat ttcagccgct tcttgccaag
    12121 catatgcaca tcgtgttagt acttttaatt ttttgaatac aatattagaa tgctgctcgt
    12181 aaaatgacaa gtaatcatta tatatcaaat cagtttttaa atttctcggt ttgtaaaata
    12241 atgctctatt attgctaaat gttactttag caacagttct attatcatgt ctatccccct
    12301 gagataattc aatatttttt atcattttta aatcatcgtt caataatata cttaactcat
    12361 ttttatcttt ttcaaatcta tcaaatatct cagttaattc attcactatg tcaaaaatta
    12421 attttcttat tattgttttt gcacatggat actgatcaaa taatctatct atacgtttct
    12481 ctctctctaa tattaccgtc aactgtttaa aatctttttg tagactatct ccctctaatt
    12541 ctccagattc cttaagtgta tgatacatat caactattat agtctcaata attggatata
    12601 catcattatt aatttctctc agaatattct tgaagtcgta attatgtatg tctgtgagat
    12661 agtttatctt ttcatcacaa atgaaataat gtgttatttc ttctatactg atagtttcta
    12721 ttactgtgct taatttctcc aacatacata tctctccgtt tcttaatttg atacaaacct
    12781 aatcattttt gcggttacta cgcagataat aactgcaact attgcattta ttatttgtat
    12841 aatttgatca cctgaacaaa ttgcacttgt tttaattcca tattccaaaa taaacggtag
    12901 caagacaata aaaaattgca ggataatacc tttccattta tctaattgat tgtaacttaa
    12961 ttctcgtaaa attgtgacac ttcccaaatt gattgctaca ctaaagagta gtaatagctg
    13021 tagtactata cgctcatctt ctttaaatac atattttaat aacataccat acataagtat
    13081 acttactaac acttttatca acagtgctgt gtacttaaag atgatgatag ttgaataatt
    13141 gattggcaca atatgttcta aataataccg ctgtttaatc aatgcttgat ttgaactgta
    13201 tatattagta gatacgatgg taaaataaaa cagcattatc tctgggatac cttctaacag
    13261 actagttgct agtacaatta atccgattag taaggcaact gttgttcgtt ttttagactc
    13321 ttgcgtataa taataacata gcccacgcat cataattttc cttccctaaa atttttggtt
    13381 aaatgaaatt aaagacactc cgaaagacaa accatacagt aaaatacttc ctcctataaa
    13441 taaaatcata agtattgggt agttatacgc atcaaatgta ccatctaatt tcataatgat
    13501 ttttattcct tccattaata gtctcaccgg aacaatagtt aatagaaaac tggctaaaat
    13561 aattgtctta atatgcttat gcccaaacaa aaatgcaccg cctaatacaa tacttccaaa
    13621 atgtaatcca acagccattg tgagaaatat ggcgcttttc atgctggctt caagcaatgt
    13681 aacgtttgat tcatatagcc atataaatcc taaaactagc ataaaattag ttcccgtcaa
    13741 aaaaagataa tttacatatc tagccgttac aatatccgga cgcttgacag gtaacatcag
    13801 ctcttctttg tgataatcaa gtgttgtata attaaatacg ctaccaaaat aagctaacgg
    13861 tgcaatgata ataataccat aagcaacaat aaccaaatat tgaacaatat caaagaataa
    13921 cataatagat agcaccgaaa gaataactgc ataaatagtt tgtagtttga gtcctgatga
    13981 cataatatct tttcttataa tactaatcat acgataaccc ctttagcata catattcata
    14041 ataaattcta agtttggttt ctcaacttca atataatcag gtagctcatt atcaatttgt
    14101 tttctgttaa gtaacacact atatccgtac gtttcttttt tgtaggctat catactagtt
    14161 tggtgtaatt gatcaaattg ttcttttgta cagtgacaca taccataatc atacaaaaga
    14221 gtcgtaattg gctcacaaaa aacaacttga cccgctttta aaaaaataac aatatcagct
    14281 atctgttcaa tatctgtagt gatatgacta gagaacagaa tagaacgttt ttcatcctcg
    14341 gcaatatacg tctgaaaaat ttctaataca tcttgtctct tcactggatc gagtgaacta
    14401 gttggctcgt ctaacactaa aaaatccggt tgatgagaca ttgacaaaac aatagaaaac
    14461 attttttgca tgccttgtga acattcctca atttttttgt actgcgagat attaaaaaag
    14521 tctagtgtct gattaaagaa attagagtcc caccgtggat aaaactttct atatatatct
    14581 tctacttgtt taattttcaa attttttggc aaataaattt catcaaaaca caccccaatt
    14641 ttttctttta gctcagtatt gtctaaatcc atagtttctc caaaaatttc tacaacaccc
    14701 gtatactgtt tttgtagtcc taatattgaa ttgatgatag ttgttttacc tgcaccattt
    14761 tccccaatga gtccgacaat atagcccttt ggaatgttaa tagtaacgtc atcaagtgaa
    14821 aactcactat ttttatagtg aacatttaat tgtttaattt ctacagcatt actcatctat
    14881 atcacctact actctcttaa ataaattgat taattctcgt ttattcattc cttgtttttg
    14941 actataactc atcaattctt taatctttat ttcaacatct tgctcaatat ttttagtaat
    15001 catttcccgt ttgacatcag ctataaccgt tccacgtcca actactgaca taattaatcc
    15061 gtctgtttgt aaaatttcat atgctttttt tactgtgata acactcactt ttaaatcttt
    15121 agccaatgtt ctaatcgctg gtaaactatc tcctgctgtt aattctccat tttttatttt
    15181 tgatttaatt tgtaatacaa tttgttcata gattggttct ttcgactgaa catttataat
    15241 catttccacc gattaattct cctcatataa taaagttcca tccccattat atcaaataaa
    15301 aaatagtatc tgtcgcaatg acgtttttat acaataaatc ctgccattaa tcagttacgc
    15361 aactattttt tcttcttttt acagccccag ccacatgatc tattacatga aagaaatgtt
    15421 gttacagctg aaattgccgg tgcacaaaat tttaatgaag ccgacaccac tggagtgact
    15481 gctctatctt gtccaaaatt atctgcacca ttgtctgcac caccaaattt agacaatctt
    15541 tccaattcct taaaatcaat tcttgaattt ttattcactg cctttccttt ctacattgcg
    15601 acatctacta ttgggtttat tgtatatgca cattatatta tttatttaat tataatgcaa
    15661 gcatttttta cccgtcaata tataaaaaat tgtttgtgta tcctaatgaa taaactatga
    15721 gcagaatttt atgcaaaata aaagaaggct taatggcaag ccttctggag ggtgttacga
    15781 ccgtttaccc caaaattgga agtaatcagt tcgcaagtat ccattatata attttcgtcg
    15841 tttggttgct ttttggccaa agtgtttttc aaaatctaaa tcatctgtga taatgtactt
    15901 gctccatgtt tcaaggggtc gccatacatc accgagttgg cggtagagct tttcaacggc
    15961 agcttgatcg ccaattcgtt ttccataggg tgggtttgaa atcataacgc cgtaccgctt
    16021 atccgttgtg aaatcagcta cttgcatttg tttgaagtta atactatgca gtaagcctgc
    16081 ttccatcgcg ttttctttcg caatctcaat catcttatga tcaatatcaa acccactaat
    16141 atcaagttca acatcataat tagcggcttc atctgcttct tgacgaaccg tttgccataa
    16201 ttctgctggc atccagctcc aagcttcaca gaggaaggag cgattaaatc cgggcgcaat
    16261 attatgacca atgagcgctg cttcaattgg aatcgtcccg gaaccacatg tcggatcaac
    16321 gaacggttta tcagggaacc acgttgtcag tgcaatgagc gctgctgcta agttctcttt
    16381 cagtggtgca tcacctttgc ccgtacggta gccccgcttg aataagctat ctcctgttgt
    16441 atcaagggtt atcagtactt tatctttatt aatcgcgact tcaagcggat aagtcgcacc
    16501 tgactccggc aagcggcctc gcttatggta agcttcctgc aaacgcgtag caaccgcctt
    16561 attaacgatc cgttgcacgt ctggcacact atagagttta gacttttgtg atttccccgc
    16621 aacaggaaag gcgccatcaa gcggaatata gtcttcccac ggtaatgctt ttgtctgttc
    16681 gaacaaacta tcaaaatccc gtgcttcgaa ctctccaata ataatcttca cacggtcggc
    16741 aatccgcaac cataaattcg ctcgcgcgat atcgtgcttc cggcctaaga atcgagcgcg
    16801 accattctca acctctacct catatcctaa gtcgcgtaat tcatccccga ctaatccctc
    16861 tactccactg gcgcatgttg ctaataaatt aaattgattc actgtttatt gaagcctcct
    16921 attcaaggtc ttattatata acttgctatt taacacattg tctttatccc ggcttagcta
    16981 aactcgcata atatatttgc ttgatctgct caaatatatt atctccaaaa tagtggacaa
    17041 tattatcatg acatataata ttgcgataac agcgtgatga tgacaactta tttatgatcc
    17101 atttgatctc ttaaatattt atagtaacta cttcctcgat caggtccaaa ggcatcgcat
    17161 aatttatggc gtagctcatc ttttgattga ctcgcataaa aaatcccttt cacttttgac
    17221 cgatctgccg gtttcacatt actccccaca atattataaa tcacctgatc cagacgtgtc
    17281 ttttgtgggt ggtgtttagg ttgtttaggc gttggcgctg gcttatggta agctgaacta
    17341 gacttcggtg aatcatttct tagcgataaa aagtcttgtc gcacattata gccctttgta
    17401 atccaatgtt taacaaccgg atcgaatcct ttatcattgc tgagtaagac gaattgactc
    17461 ttcggaaatt cttgcaaaaa atatcctaaa taagaactca tttggaagtc taatgcattt
    17521 gccgagccat taatcacctg aatgaactcc actttacaat ccaattgcaa caattcattc
    17581 actttttcga attgcatcgt gttatccgcc ttggaataaa aaacaaagca ataatcgcgc
    17641 ttcgttaact cctcgcaata actaataaat tttttagaga tattttcgta atcaactagt
    17701 gtaatacttt tgggtttgtg caccatacgt tgaataaaat tcaccacatc attcctttcc
    17761 tattctaatt atctttcgtt tttttatcta tgaataaaat cctcccagtg caaccacatg
    17821 ggaggatcaa ttgacctaat tgtatccttc actataagcc atgttctgtc taaagaaacg
    17881 ctaggctcgt ttcttcgaga taatcatctg tctatagtgt tacctatctt ccgcatcatt
    17941 catttctgct ttggaagtgc ctctaccatt atgtttgagt tgcttgctcg aggggtttac
    18001 ccgttccacc gccaagattt ctctaggcgc ttcgtcactg tggcactttt caagactact
    18061 tagacatagc gaaccttagc ctgtttatct gccgtcacct attcagggcc gtagcttatg
    18121 atttcactac gcacgaacac tacaggcatc gcagcctgtg caagcatgga ctttcctcac
    18181 acttgtctag caagtgcgca attatccgta aagaatacag ttcttattta aaaaatatca
    18241 tcacttaatt ataaacttag ttgtcaccgt tctccatctt cgctccgaag acatgatgtt
    18301 ctaagttcga aatacgcttc aagatatcaa tattggtggc catcatctgg cttgatggtt
    18361 gcttcggttc agctggcgca gccggttgcg gttgtggcgc cggtttctga gctaactgct
    18421 cctccagtga cgcgatttcc ttcttcaagt cttcgatctt atcatcaaac actttataat
    18481 cgcgcataat aatatctaag aattcatcca cttcttccgg attatatccg cgcattgatt
    18541 tcgaaaattc tttttcaaag atttgttttt gatttaattc tgtattgacc attcatagca
    18601 cctctttatc ttcttctgta aaatgtcatc actcatatca taccagaact cgcccaaaaa
    18661 gtgaaggatt tccgcttaat tcctctcttg ataatcagca acaaatgatt gtaaatcatc
    18721 catatagatc tgatcaagca aataatcatg cacctcctga tgggctttca cttgttcata
    18781 caagtaactg gatttccctt catattcatt atcataaatc aacagtaaac catccgtgtt
    18841 atttaaaata aattgcgcat tcccacttaa ttgccccccg tgtttatacg gctcatgaga
    18901 agtatagttc atataatctg cctgctcaat tgctttttgc aacagtaatt gattcttttc
    18961 gttccaacta ttgccatatt cttgatacgg caacaacaac accaattgca gattaggata
    19021 ctcttcccgt agttcctcta caacctctgc tgtccataac tcaataccta actgaccgct
    19081 cgtaatcacc cattctaacc cattttggat atactggcta aggcttgcct tcaaaaattc
    19141 tttcacaaaa aacagcttat catcgtcttc agagaagatt cccaattcgt aagaccgata
    19201 gccactaaca aataatcgtt ttatcataaa atccctcttt tttattttgc ccaagtttgt
    19261 taaactatta aggataacac gattgatggg agtgagtatt tcgtggtaaa ctatcccaat
    19321 ggtgaaccct accacagtaa gcatgacaaa aaaagaagac atttgcaagt caaaccaaaa
    19381 acaatgactt atagtaatcg cggaatgacg cttgagcgta tgattaatgc ttcgattaag
    19441 tactatcgcg agacgggaca agctgttctg cacaagaaac cgacgcctgt tcagatcgtc
    19501 aatgtagatt acccgaggcg aagtgccgct aaaattaccg aagcgtactt caaaagagcc
    19561 tccaccactg attataacgg tgtataccgg ggctattatt tagattttga agccaaggaa
    19621 actaaaaaca aaacatcttt ccccttatct aattttcatg aacaccaaat tagacatatg
    19681 cagcactgct tagagcaagg tggcattgtt tttgttcttg tttatttttc tcatctaaga
    19741 caactttact tactagatgc gcaatatttt attgattact gggaagatca cttagcaggt
    19801 ggacgaaaat ctattcctct caccattttt gaggcggaag gatatcctat ttcactcggt
    19861 tatgccccac aaattccttt cttacaggct gtggacgaat tcatatcaac aatgtaagac
    19921 gctttaattt tcaaaaagga gaacaactat atgagcgaca ataattactc aagacaatca
    19981 agaaaacaaa aaaagaatca ccaaaagaaa tcaaaacgaa aagtaacaca tacatctgct
    20041 gtaaatctct ggctaaaacg tggattgctc gtaatatttg cagccattat gcttgtactt
    20101 atctcaggtg ggggattatt cctctaccat gctcaggggg ctcccgaatt aacggatgac
    20161 gatttatacg gtgcctatta ttccagctta gtggataaag atggtcatga attttaccgt
    20221 cttggcacgg atagccggga gttcgcttca gcagaagaat acccggaact cttgacagat
    20281 gcggtgaagt ctattgaaga tcaacgtttt gattcacata atggcttcga ttttatcgga
    20341 attggtcgag cagctgtcga ttacttacgt gcaggtgaga ttgttagtgg agggagcacg
    20401 attacccaac aactcgtgaa gctctctgtc ttctcaactc tacgtgaaga ccaaaccatc
    20461 gaacgaaaat cccaagaaat ttggctatcc atgcaattgg aacgccgctt atccaaagaa
    20521 caaattatga ccctttactt aaataaagta cacatggctg gaaatgttta cgggatggga
    20581 acagctgcca aagaatacta tggcaaacat gtcagtgaac tcgagctcca tgaagcagcc
    20641 ctctttgctg gtatgccaca atcaccaaat agctataatc cctacaccga accggaacgc
    20701 gctaaacagc gccgcgatga agtgttagtt gcgatgtaca acaatgacaa aatcactaaa
    20761 gaacaaatgg aacaagcaca agctattccg atcgaacaag gcttacaaga aaaagtcgaa
    20821 caaactgatg aagatacact attattcgat agttatctct cagcagtatt ggatgaagtc
    20881 tatgagaaga ctgactttga tccatataaa gctgggctag aaattcacac caactacgat
    20941 agttctgtcc aacaaattct tcacgatgta gcacatagtg aagattacat cagcattgat
    21001 agtgatatcc aaacagccat cagtgttgtt aatccaaata acggtgaaat cttaggtatt
    21061 ttaggtggtc gtaacttaca agggcaactg tcttacaacc gagcaacaaa aaatagacga
    21121 aatgttggtt caaccattaa acccattacc agttacggcc cggcaattga atacaaccaa
    21181 tactcaaccc atgaacaaat tgtagatgaa ccctactccc cagctggctc aaactggaac
    21241 ttcaacaact atgataatca atacctcggc caaatgagta tgcgcgaagc attggtccaa
    21301 tcacggaaca ttcctgcagc caaaataatg aatgattata tgaatatcga aaatgtcgaa
    21361 gcatttgttt ctaagcttgg tctcgatcca aaagaaatat cgggtgcaaa tggactagtt
    21421 ccttctaact caattgacgg tagtatgacg ccgcttcaac ttgccggtgc atacagtgcc
    21481 ttcgccaacg aaggaatcta tactgaacca cacaccgtta acaaagtggt cacacagcgc
    21541 ggtcaagaaa tcgatatgac acccgaaagt actcgggcaa tggaagatta tacagcttac
    21601 atgatgaccg atatgctaaa aggtgttcca gaagctcgtc ctgaaataaa tgttccagga
    21661 atctatcatg ctggtaaaac gggaacgaca aactttacag atgaacaatt tgaagaatac
    21721 aatcttcctc gaggaatggg actcattcct gattcatggt atgttggtta cacccaagat
    21781 tttgtcattt ctacatgggt tggttatgat gagccattca aggaagggaa ccagttaata
    21841 ttcggtgata caacccataa cttacccctc tattactata gtgccattat gaaccaactg
    21901 gctcaaacaa ccgaaaatac cgactggatc aaacccgact cagtatctga agtcaatgta
    21961 gtgagtggat caagtcccgc tcaactaccg aaccgctcaa ccccattctc tagtatcaca
    22021 acagagctat tcgtcgcagg tacagaacca caatctgtcg ctccagcacc cgttcagcca
    22081 cagccgactg aaccgcaagt aaccgatgaa gacgaaaaag ataaagagga ttctgaagaa
    22141 gataataaag ataataatga acaaaatcca actgatccta tcgatgaaga aggtagtggc
    22201 caacaacctg gcactcaacc aaacgatcca aatgaccaaa atagccaagg cgcacaagaa
    22261 ccacaaacct ctggatcagg tggtgctggt ggtaacaact aaccaaacag gacaaaattt
    22321 cacccttaaa tcataaaaca aagacccctt ttgaaggtca gcattgtgta ctgaccccca
    22381 aaaggggttt tctcttaaca attcatttat ttacgaccag tatttttctg cttttcctct
    22441 tctctgagtt tctctaattc cttatcatgg cgcttcttcg cccatcgatt aactggggaa
    22501 tcttcccctt ttctaacatt gaaactgtta atcactgtaa acagaccgac tccagctgct
    22561 aatacgccca ttatcgtatc atattgcgtc aaataaacac ctagtgccac aatgaccagt
    22621 cccattacaa ataaaattgt cccgttattc cgtttcattt catcatctcc ttgacttctt
    22681 ttatccggat tgctataatt gtatgtggtt agttcatgga ggattgtccg agtggcttaa
    22741 ggggc
//
