LOCUS       NZ_CP040411            22457 bp    DNA     circular CON 23-APR-2024
DEFINITION  Dolosigranulum pigrum strain KPL3256 chromosome.
ACCESSION   NZ_CP040411
VERSION     NZ_CP040411.1
KEYWORDS    RefSeq.
SOURCE      Dolosigranulum pigrum
  ORGANISM  Dolosigranulum pigrum
            Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
            Dolosigranulum.
REFERENCE   1  (bases 1 to 1941401)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Eslami,S.M., Gao,W., Bomar,L., Fernandez Escapa,I., Roberts,R.J.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     The nasal commensal Dolosigranulum pigrum exhibits stable synteny
            and highly similar strain circulation over a 20-year span
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1941401)
  AUTHORS   Flores Ramos,S.Z., Brugger,S.D., Skeete,C.A., Cotton,S.,
            Johnston,C.D. and Lemon,K.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2019) Microbiology, Forsyth Institute, 245 First
            Street, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-AUG-2018
            Assembly Method                   :: HGAP v. 4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 530x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017655645.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 02:25:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,851
            CDSs (total)                      :: 1,781
            Genes (coding)                    :: 1,758
            CDSs (with protein)               :: 1,758
            Genes (RNA)                       :: 70
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 23
            CDSs (without protein)            :: 23
            Pseudo Genes (ambiguous residues) :: 0 of 23
            Pseudo Genes (frameshifted)       :: 9 of 23
            Pseudo Genes (incomplete)         :: 15 of 23
            Pseudo Genes (internal stop)      :: 3 of 23
            Pseudo Genes (multiple problems)  :: 3 of 23
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:41:13
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1454542
            Orig. end                         :: 1476999
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040411.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
FEATURES             Location/Qualifiers
     region          1..22457
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="3"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22457
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22457
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12457](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12457)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(228..237)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.05"
                     /tool="antismash"
     gene            complement(814..1218)
                     /locus_tag="FE334_RS06755"
                     /old_locus_tag="FE334_06735"
     CDS             complement(814..1218)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014608.4"
                     /locus_tag="FE334_RS06755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06735"
                     /product="OsmC family protein"
                     /protein_id="WP_077863003.1"
                     /transl_table=11
                     /translation="MLYEVVAVNETGIEGESYLVDGETYLTSSPMSEAPGTNPEQLMGL
                     ALATCFNATLHAVLKERGLEPESRVQVTVQLHQDEENKEYYFTLDLEAAVAQVDLQEAK
                     EVVKVAHKRCPVAKVVGNYEGMTVKTVPFN"
     CDS             complement(1349..1456)
                     /gene="allorf_1455891_1455998"
                     /locus_tag="allorf_1455891_1455998"
                     /protein_id="allorf_1455891_1455998"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSFDRVVSASSRRSILCGVSFLFILGKIKTISQKE"
     CDS_motif       complement(1427..1456)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSFDRVVSAS"
                     /locus_tag="allorf_1455891_1455998_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1349..1426)
                     /prepeptide="core"
                     /locus_tag="allorf_1455891_1455998_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="2734.3"
                     /monoisotopic_mass="2732.6"
                     /core_sequence="SRRSILCGVSFLFILGKIKTISQKE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSFDRVVSAS"
                     /leader_location="[1426:1456](-)"
                     /alternative_weights="2752.3"
                     /alternative_weights="2770.3"
                     /alternative_weights="2788.3"
                     /alternative_weights="2806.4"
     gene            complement(1490..2749)
                     /locus_tag="FE334_RS06760"
                     /old_locus_tag="FE334_06740"
     CDS             complement(1490..2749)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE334_RS06760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE334_06740"
                     /product="hypothetical protein"
                     /protein_id="WP_077863004.1"
                     /transl_table=11
                     /translation="MKLKHILKTASVLALLTGPSAITTVESVYAEEAQDKVADSETNLE
                     ALSQQVRSSVQTIEDLNDELAQLDTTIADVESEIEQAEADISQQEAVIEDYFDQAKSRL
                     QNLQLSNVNENAVLSFLEADSLQDLLARVNAVVQLSQANSDQMQSAQDQKDKFDQLVAT
                     LESKQNDLTDKKEAIEEKKQAVNTELIELEALIEENQGAFETLKNEDEIAEVCLRAEEL
                     VKEHQDQETANTETPDQATDQSEELDNQPEQSEENTATKEATEQSEPEPEAEQAPQVEE
                     TPVQTEQPEQPEQAQPESDVQEPVEAQPESSEESVQPQTAGATVAQYSIDDLEFQGIIH
                     ALGKKWTFYSERVLPGGGLNIPGRHTADGFVRDGEGYIVLAASSSVGHGTIVDTPFGSQ
                     GKVYDTCASCHADWFDVYTR"
     gene            complement(2769..3368)
                     /locus_tag="FE334_RS06765"
                     /old_locus_tag="FE334_06745"
     CDS             complement(2769..3368)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="FE334_RS06765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06745"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_208965602.1"
                     /transl_table=11
                     /translation="MDLAIKNNAITGLFGDNGAGKTTLMKALTTQIKIDSGEMSIENHV
                     IHFNQPTNKAIGVLIEEPSLYPYLSGREHLNLFKKLEEQKNNDLSIEWLIDEFKLEKFI
                     DMPTKKYSMGMRQRLGIAMTLVTDPDIIVLDEPFNGLDPKSVKSLRDTFITLRNKGKTL
                     LISSHLIREIAEIVEFSCYNDRCRLKDTTYDVTIII"
     gene            complement(3465..4076)
                     /locus_tag="FE334_RS06770"
                     /old_locus_tag="FE334_06750"
     CDS             complement(3465..4076)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024741.4"
                     /locus_tag="FE334_RS06770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06750"
                     /product="ABC-2 transporter permease"
                     /protein_id="WP_077863006.1"
                     /transl_table=11
                     /translation="MKALLFKEFQMTFNWKTFVSYIALLFLIGTIFGHIQVALFAFTFA
                     LMHSSILEDDINDADVFINSLPVSRRMVVASKFLATMIEVALMLGTVYGSKIIVPLFSD
                     LNWQTALLTFAGALILIGFYYTCYYVFGLKLLNVILVILFIMATVVFPILLNLNYLTKL
                     IQIIQFLSEGIGLVIATSSSLLLVIVFYVISYKVYQRKEF"
     gene            complement(4085..4969)
                     /locus_tag="FE334_RS06775"
                     /old_locus_tag="FE334_06755"
     CDS             complement(4085..4969)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016648319.1"
                     /locus_tag="FE334_RS06775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06755"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_077863007.1"
                     /transl_table=11
                     /translation="MENVVEFQGVEKTFDHFKLKELNLKIKKGYITGFIGPNGSGKTTT
                     LKLMMQLLRADQGRVTIFGQEMTQQNYQLKDRIGFVYAENVLYKSQTVAQIGKLVSRFY
                     SKWDQAIFDQYIEKFNLPLDSKVDKLSTGMKTKLSLALALSHHAELIILDEPTSGLDPV
                     VRRHILDVLFELIQDEDKTIFFSSHITQDIEKIADYIIFIKDGEIIFDEEKYNILERYK
                     LVKGPVDLLDGDIRDLFISIEEKQVGFTGLTTESATLIELFNDLVTIEKASLDDIMVFF
                     DENQSTALNDGRK"
     gene            complement(5043..5435)
                     /locus_tag="FE334_RS06780"
                     /old_locus_tag="FE334_06760"
     CDS             complement(5043..5435)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006309247.1"
                     /locus_tag="FE334_RS06780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06760"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_208953354.1"
                     /transl_table=11
                     /translation="MIHIVLSKQSSDPIYEQIRLQLKQAILRGELASGEQLPSIRALAR
                     ELEVSVITTKKAYESLEAEQFVESIAGKGTYVAELNPDAIRTKQIIKIKQDIAQIVESA
                     QVIDLTLPELLEMMEETFQQESQKDT"
     gene            complement(6003..7031)
                     /locus_tag="FE334_RS06785"
                     /old_locus_tag="FE334_06765"
     CDS             complement(6003..7031)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019474.4"
                     /locus_tag="FE334_RS06785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06765"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_077863009.1"
                     /transl_table=11
                     /translation="MGIIWIIGYYWADLVIGITRVFSKMRQRLKRRRVKPAKQANVYKN
                     VEYKSDYPNNKLDIFIPSHSSHPTRSPEENRIKEQQNTCDNENDMEIRPALYPVIVYFH
                     GGGFAWGDKIDERRYLLEFVKQGYAVISANYALTPTYKYPVPIIQASNVMDFVASEGQR
                     YGLDLDNVVLAGLSAGGHLAGQLALVESSSAYANRLGLRQHATLTFRGLMLNSALIDPK
                     RSNQVGHWLINWLFSVMGFSYMDMNPSRMKENTLAEANLLNHVNDAYPPVYVSDGNRVS
                     FTQQATDLVAQLRAKDIYVQSNIYSDNYPHRMYHGYEAQLWLKEARDNIHKQLDFLDTI
                     IE"
     gene            complement(7126..7533)
                     /locus_tag="FE334_RS06790"
                     /old_locus_tag="FE334_06770"
     CDS             complement(7126..7533)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014608.4"
                     /locus_tag="FE334_RS06790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06770"
                     /product="OsmC family protein"
                     /protein_id="WP_004635395.1"
                     /transl_table=11
                     /translation="MLYEVVAVNETGIDGQSYLVDGESYQTSSPTSDEPGTNPEQLMGL
                     SLATCFNATLHAVLKEREIEPKSRVQVTVQLHQDEVSEEYYFTLDLTAAVADIPLDEAE
                     TIIQATHKRCPVAKIVGDYKHLTVETVPFEA"
     misc_feature    complement(7812..7826)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.88"
                     /tool="antismash"
     gene            complement(7814..8476)
                     /locus_tag="FE334_RS06795"
                     /old_locus_tag="FE334_06775"
     CDS             complement(7814..8476)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="FE334_RS06795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06775"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_172764092.1"
                     /transl_table=11
                     /translation="MEKNVKELNFTINEGEFISFVGRTGCGKTTIIKLILSLYNNFEGN
                     ILLNNIDKEVYDLKSYRQLFGTVLQDETLLNDTIQKNIDPTHSHTISKIREAAKLACLD
                     EDVMNRMPSKYNTEIGDNGRNLSGGQRQRVAIARALLTNPKVIILDEGTSQLDVSTERE
                     IFNNLKKKNITIIAVTHKLSTTTISDCVYVLKKGKIIAHGKHEKLMQNNRYYSDFFR"
     gene            complement(8460..8891)
                     /locus_tag="FE334_RS06800"
                     /old_locus_tag="FE334_06780"
     CDS             complement(8460..8891)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE334_RS06800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE334_06780"
                     /product="hypothetical protein"
                     /protein_id="WP_208965603.1"
                     /transl_table=11
                     /translation="MMKTSNYGEALYNKWVKNYNEQMHLEFKRQRLLGMYRSLIISYRL
                     LPSVTVLFIGSNFVNQGMLTLGQVMSFLALGNTLLSPLAILIQNIFDFQYSKNNIDRLS
                     EIITAKSEKNFDGREINSFKNIKFQDVNFSYSGINGKKC"
     gene            complement(9213..9929)
                     /locus_tag="FE334_RS06810"
                     /old_locus_tag="FE334_06790"
     CDS             complement(9213..9929)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015377.4"
                     /locus_tag="FE334_RS06810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06790"
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="WP_208965605.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.7e-35, bitscore:
                     116.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIKFVQQLSESDCGIAALTMVLNYYGCKLHISDLVEKCSISRD
                     GVHLRDLMNVANEYGLKSKAVELNKKENIFSEKIVFPCIAVLSMSHYVVIEKAKRGTIY
                     YLDPECGRIIMDGSEFSKKFTGILLLFFPENIKKQKSQNKIIEILTLGEIKKKFIVGVI
                     FFSFIIQLFVLLMPLFTEYMIDNVINGIALVSHVKLIIGILFAILSYGVFSFVRELLTT
                     LLEIKYISTLKKKCSA"
     gene            complement(10001..12457)
                     /locus_tag="FE334_RS06815"
                     /old_locus_tag="FE334_06795"
     CDS             complement(10001..12457)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="FE334_RS06815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06795"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_244325507.1"
                     /sec_met_domain="DUF4135 (E-value: 3.9e-90, bitscore:
                     299.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3e-64, bitscore:
                     213.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNGGQTVIILHFEEGTSVVYKPRDLKMDVTFQSTIKWFNEVTKS
                     HLYSLKIINHTEYGWVEYIPHEECKDYSDFKNYYTELGQLLFLFYLLRGNDIHYENIIA
                     KGKHPVLIDLETLFHNNTSNTSGIDTAADRVNELLENSVRTVGILPNLVWAQNGKNGVD
                     ISAISTSENKEIPIEQASITNVNKDNMKVEYKTSTLASQKNNPYIIGEEISLTSYHKYL
                     KKGFIESYTKIKNINKKEIINQVENYKEIYARQILRPTQYYTTLIQISLHPDFLRSAID
                     REMLFSKLWIYFDENNSFRKVSEIEFTSLLKNDIPWLISNVSKNNITTKDGSEIESIFK
                     HSSIALVKEKINILGDKDLTLQVELIETALNYDSEYNKAESQRENDRKIIEINDDKLNK
                     NHLDQQLLEISTNIGDYLINQSFIGMNGDVSWIDMNVIGEKANDWNMVPTSMDLYSGLS
                     GIMIYFIFLYKETKQNKYLIMVKRCYKSIINYIKNVRKRTNINSEVMFGGFSGETPIIY
                     ALTILEEELGGIFDLDELEKIRSWIFKECKKNISVGNEHDIIIGSSGVIAILLRYYDLT
                     SNDAILEVCQQYAEQIIDNYIEMDNNSIAWIGIASRNALGGFAHGVSGIVWALSKLYSY
                     LPDERYIEVIEKALRYEDYLYSEDDKNWVDRRETEEGIEYNNLSSNMPVAWCHGASGIL
                     LSRASLKKHNLPLSEKRKNKIDEDIEIAVRTTLKNGFGHSHCLCHGDLGNMLILKYASS
                     ELNTKNDIDKRYDIYMSHLISQLKDKWECGIPYKNSPGMMLGLSGIGFGLLSLMNEDLP
                     FILLLE"
     gene            complement(12484..13227)
                     /locus_tag="FE334_RS06820"
                     /old_locus_tag="FE334_06800"
     CDS             complement(12484..13227)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE334_RS06820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE334_06800"
                     /product="hypothetical protein"
                     /protein_id="WP_004635388.1"
                     /transl_table=11
                     /translation="MKLIDKFKNGLYSFERDIQHDETNNYKSENRLQYWKKFLGVNERE
                     IENILSNGLGINTANLNELLSENDNFSCKVTETNVLWNQLIHDLQVLSIESIILPEFYI
                     IGDIGQKELPMFYGFHEPFLKLAILRFENYWKNIPGISDNVFNKLLIYLYDQLAEISYR
                     TLILELNIAREENKLAGETSEERYNYFSTQYLSDNYWLILEEYPVMFRLMCEATQKWIN
                     NTTRFIDRILSDKDDLEKLLKLREN"
     gene            complement(13314..13541)
                     /locus_tag="FE334_RS06825"
                     /old_locus_tag="FE334_06805"
     CDS             complement(13314..13541)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004167060.1"
                     /locus_tag="FE334_RS06825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06805"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_004635387.1"
                     /transl_table=11
                     /translation="MKNKVNNWKTPVYEKEEDYDNPAGDIFRELKSDDIDKVMASGTAN
                     TYCRCYSGRHSCGRACTITAECPVFTVACC"
     CDS_motif       complement(13416..13541)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKNKVNNWKTPVYEKEEDYDNPAGDIFRELKSDDIDKVMASG"
                     /locus_tag="FE334_RS06825_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13314..13415)
                     /prepeptide="core"
                     /locus_tag="FE334_RS06825_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="3422.9"
                     /monoisotopic_mass="3420.5"
                     /core_sequence="TANTYCRCYSGRHSCGRACTITAECPVFTVACC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNKVNNWKTPVYEKEEDYDNPAGDIFRELKSDDIDKVMAS
                     G"
                     /leader_location="[13415:13541](-)"
     gene            complement(13590..14306)
                     /locus_tag="FE334_RS06830"
                     /old_locus_tag="FE334_06810"
     CDS             complement(13590..14306)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="FE334_RS06830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06810"
                     /product="ABC transporter permease"
                     /protein_id="WP_004635386.1"
                     /transl_table=11
                     /translation="MVLEFKKMKRSKLIIVLILIVVLNIGIHYLMGNVKYVGIPYAAEP
                     GWTLQNTLIVGTYYLLLPVFTLIGSASFIIERENSVYINILTIPVRKSHLILNKSKFIW
                     VVSMIFTSSIFVFTLVLEKIHSNILTQEIVLKYLFEYVVHSNGLYVIAMLILSVIIYMD
                     YNMQLAVMVGFVSSFVSVFIEQTAISYLYPVNALFNISGFKESNLYEYSSSVVILCVIA
                     ICAVFIYKKIAQQESW"
     gene            complement(14326..15060)
                     /locus_tag="FE334_RS06835"
                     /old_locus_tag="FE334_06815"
     CDS             complement(14326..15060)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="FE334_RS06835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06815"
                     /product="ABC transporter permease"
                     /protein_id="WP_004635385.1"
                     /transl_table=11
                     /translation="MLDLVSTEITKITRMKQMWVYASVLGIYITMMSVYTAQAVGLFDQ
                     FIHLYKFSLSYTGFLLLPFILLSLSSSTISDDYRNEVMKNLTVIPISKQKIIAAKLIAI
                     YIVLSVAMVMIWISVCVIGYVTRFRFSMTWLLIFRYLWLCILTSLVIFLSMLPVTLISV
                     ATKGNVVITNLIGSMYIIASFFLTNFMNGIIPLATAPHIIWYGSMEGVEVNSNIALMVI
                     SIIFYTIIVLFAMNKILKKQEL"
     gene            complement(15065..15982)
                     /locus_tag="FE334_RS06840"
                     /old_locus_tag="FE334_06820"
     CDS             complement(15065..15982)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010247638.1"
                     /locus_tag="FE334_RS06840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06820"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_004635384.1"
                     /transl_table=11
                     /translation="MYYMKNVIEINNLTKSYDNVAVIKSININIVEGTIHALLGKNGAG
                     KTTILKSILGLIKPTSGSIFILGENQLTEKGRNVLKQVGCMIETPGFYPNLTGTENLSI
                     FAKLRELDKQAVQEALTIVNLPYADSKKFKEYSLGMKQRLAIANAIMHDPDILILDEPT
                     NGLDPSGVIEIRELCKEMKRQGKTLLISSHILSEVEQVADEVSIIDEGELVKYINLKKM
                     NENSQVTIHIFTSNFDKVKSVLLEAGVSQHNMINTAKGVRLLSKDMDISEVNKLLTQND
                     VDIEGIMREKLTLEEQFQRVTETR"
     CDS             complement(16566..16643)
                     /gene="allorf_1471108_1471185"
                     /locus_tag="allorf_1471108_1471185"
                     /protein_id="allorf_1471108_1471185"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRVAMTGSFSYRHICCGVFLINKIM"
     CDS_motif       complement(16620..16643)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRVAMTGS"
                     /locus_tag="allorf_1471108_1471185_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16566..16619)
                     /prepeptide="core"
                     /locus_tag="allorf_1471108_1471185_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="2026.5"
                     /monoisotopic_mass="2025.0"
                     /core_sequence="FSYRHICCGVFLINKIM"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRVAMTGS"
                     /leader_location="[16619:16643](-)"
     gene            complement(16685..17986)
                     /locus_tag="FE334_RS06845"
                     /old_locus_tag="FE334_06825"
     CDS             complement(16685..17986)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FE334_RS06845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FE334_06825"
                     /product="hypothetical protein"
                     /protein_id="WP_004635383.1"
                     /transl_table=11
                     /translation="MKLKNILKTASILALLTGPSATMTVDHVYAEEAQDKVADSETNLE
                     DLRQQVRSSVQTIEDLNNELVQIDETIDGIEAEIAQTEEDISQQEAIIQDYFDQAKSRL
                     QNMQLSNVNENAVLSLLEAESFQDIIARVNAVVQLTQANSDQIQSLQAQKDELDQLVQS
                     LETKQTDLSNKKETIDAKKQSVHTEIADLERLIEENREDFETLKEESEIVEICRRAEEL
                     VEERQAEQEVQEDASSNEEAKQVASQSAEETQQPQAEETVAIEENEEPAEPTDDSAAEQ
                     SVEEPQVTETEPAEAEQSQPEPETQKQPDQQVQEESQTQTEPEVQEEPIQPQAAVPTTA
                     QYSIDDLEFQGVINALGKKWTFYSERVLPGGGLNIPGRHTADGFVRDGEGYIVLAASSS
                     VGHGTIIDTPFGSQGKVYDTCASCHAGWFDVYTR"
     gene            complement(18261..18905)
                     /locus_tag="FE334_RS06850"
                     /old_locus_tag="FE334_06830"
     CDS             complement(18261..18905)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635382.1"
                     /locus_tag="FE334_RS06850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06830"
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="WP_208965606.1"
                     /transl_table=11
                     /translation="MTPNKENFLKAIYELGGMSKLINNKSLAEYLNVSAAAITDMNTRL
                     VKQSIITYEPYKGVKLTDKGVRIVNQLIRRHRLWEVFLAEKLGYEWDEVHTDADLLEHI
                     SSDKLIERLDAFLGHPTVDPHGDTIPTSDGKVIVNQYHALVECKQGESFKVKQVDDDTE
                     FLTYLTDKGIQLNETYQITEIEPYEGPITLTNNDEENILVSYKAAFRIFGQ"
     misc_feature    18992..19006
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.19"
                     /tool="antismash"
     misc_feature    19043..19056
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: strong, score: 21.97"
                     /tool="antismash"
     gene            19077..19637
                     /locus_tag="FE334_RS06855"
                     /old_locus_tag="FE334_06835"
     CDS             19077..19637
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014669.4"
                     /locus_tag="FE334_RS06855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06835"
                     /product="biotin transporter BioY"
                     /protein_id="WP_111949520.1"
                     /transl_table=11
                     /translation="MRTLTTKDLVYIAVLTAMLCVSSLVAIPVGIGIPITLQVFFWLLI
                     PALLKAYRGFLSLALYVLIGLIGIPVFAGGTGGFQAVLSPSFGFLLGSLIIALYIGKVA
                     QKRPSLLTMILHMIVAILILYTIGILYQYFIFNVIAESGGSTTLISLIIANVSSFLPLD
                     ILKAILAGIVYDRLIRHTRFKNI"
     gene            complement(19684..21339)
                     /gene="treC"
                     /locus_tag="FE334_RS06860"
                     /old_locus_tag="FE334_06840"
     CDS             complement(19684..21339)
                     /EC_number="3.2.1.93"
                     /GO_function="GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635380.1"
                     /locus_tag="FE334_RS06860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FE334_06840"
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="WP_208965607.1"
                     /sec_met_domain="Alpha-amylase (E-value: 5.6e-95, bitscore:
                     315.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKNFHDKVVYQVYPKSWKDTTGTGMGDLQGIIEKLPYLADLGID
                     LLWLNPFYKSPQNDNGYDIADYQSIDPMYGGFDTFDKLVQEASKYNIGLMLDMVLNHVS
                     TEHEWFQRALNGEEQYQDYFILRQAQPDGSLPTNWESKFGGPAWNQLGDSDYYYLCLYD
                     KTQADLNWHNPEVREALYDVVNFWIDKGVKGFRFDVLNVIGKSQDLKDAADGVGKKEYT
                     DTPIVHEWVRELNKRTFGRYDDIITVGEMSSTDVSNSVQYSHSESNKLDMVFSFHHLKV
                     DYKNGDKWTLMDFDFDELKRLLDHWQTGMQAGNGWNALFWNNHDQPRSNSRFADPVNYP
                     YESATVLATTIHLLRGTPYIYQGEEIGMTNPNYESIDQYDDVETHNAYRTLLAQGMNNS
                     EALAIIQAKSRDNSRTPMQWTSEDQAGFTTGQPWLEIASNYKYINTNVTDPSQRIRDYY
                     KQLIRLRKDYAVISEGTYRSIQLDHPDVYSYMREYDNQQVLVFNNFYGKQTAIDVPKDF
                     LKKDARVLIGNYDQHALEQQLVLQPYESIAFLLE"
     misc_feature    complement(21897..21912)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.72"
                     /tool="antismash"
     misc_feature    complement(22274..22292)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.09"
                     /tool="antismash"
ORIGIN
        1 cacactgaat agccagttaa ttaaccaatg gcccacctga ttggaacgat tgggatcaat
       61 taaagcactg ttgagcatga tgccgcgaat agttaagtcc ggatgttgac tgagccctaa
      121 acgatcagca taagcactgg atgattcagc taacgctagc tgcccggcta aatgaccacc
      181 tgctgacaat cccgctaata caatattatc cgggtctaag ctatattgtt ccccttcgtt
      241 cactaaaaaa tccatcactt cgcttgcttg tataatcggt acgggatatt tatacatcgg
      301 tgtgagcgca tagttagccg ctacaaccgc ataaccagcc ttcacaaact ctaacaaata
      361 tcgccgctca tcgatcttat caccccaagc aaacccacca ccatggaaat agacaatgac
      421 cggtttcaac atatccgata cttcagaatg actagcttct aaaatatctg gattagacgg
      481 atctttttct tgcttttgat ctgttaactc tggagtagga tgaacgctac ttgactcacc
      541 aggtacataa atgtctaact tattattcgg atagttactt ttataaggaa tatttttata
      601 cacattcgct tgcttagctg gcttaatgcg acgacgctta aaccgctgat gcaacttgct
      661 gaatatccta gtaaatcgaa tcactacgtc agcccaataa tagcccacaa tccaaatgac
      721 accaacaata gctaagagac tgctgattag ctttcctaat ttctttattg ttctgatcag
      781 acccatccat ccctttctaa atacacgtca cccttaatta aatggtactg ttttgactgt
      841 cattccttca taattgccaa ccacttttgc taccggacat cgtttatgcg ctactttgac
      901 aacctcttta gcttcctgta agtcaacctg ggccaccgct gcttctaggt ccaacgtgaa
      961 ataatattcc ttattctcct catcctgatg caactgtaca gttacttgta cccgactttc
     1021 tggctcaagt ccacgctctt tcaaaaccgc atgcaatgtt gcattaaaac atgtcgccaa
     1081 ggctaatccc attaactgct ctggattcgt tcccggtgcc tcactcattg gactggacgt
     1141 tagatacgtc tcaccatcca ccaaatacga ctcaccctca attcctgtct cattcactgc
     1201 cacaacttca tataacataa tacaacctcc tattatcaat atattaacta atattttttc
     1261 ttatcatata gtctaatcta acctatcgac acttatatta tagcatgatt agcaatacat
     1321 ttcacatata agaactaaac attaactcct attccttttg actgattgtt ttaatttttc
     1381 caagtataaa taaaaaagaa acaccacaaa ggatgcttct tcgagagcta gcggaaacga
     1441 ctctatcgaa agacaagttt gtggtgttta ttgatttaat ttgattaaat tatctcgtgt
     1501 atacgtcaaa ccaatctgca tggcaactgg cacatgtatc atacactttt ccttggctac
     1561 cgaatggcgt gtcaacaatc gtgccgtgac cgacgctact gctagctgct aagacaatgt
     1621 agccctctcc gtcacgaaca aatccatctg ctgtgtgacg tccggggatg ttcaagccac
     1681 cacctggtaa gacacgttct gagtagaacg tccacttctt accgagcgca tgaataatac
     1741 cttggaattc taaatcatca attgagtatt gagctactgt agctccggct gtttgtggtt
     1801 gtacagattc ctcagatgat tccggttggg cttctactgg ctcttgaacg tctgattctg
     1861 gttgggcttg ttctggttgt tctggttgtt cagtttgtac tggtgtttct tcaacttgtg
     1921 gtgcttgctc agcttctggt tcaggttctg attgttccgt tgcctctttt gttgctgtgt
     1981 tttcttcaga ttgctccggt tgattatcta actcttccga ctgatcagtt gcttgatccg
     2041 gagtttcagt attcgccgtt tcttgatctt ggtgctcttt gacgagttcc tctgctcgaa
     2101 gacaaacttc agctatttca tcttcatttt tcaatgtttc gaaagctccc tgattttctt
     2161 caattaatgc ttctagttca atgagttcag tattgactgc ttgttttttc tcttcaatag
     2221 cctctttttt atcggtaaga tcgttctgtt ttgattcaag tgtcgctact aattgatcaa
     2281 acttatcttt ctgatcttgg gctgattgca tttgatctga atttgcttga cttaattgga
     2341 caaccgcatt gacacgggct aacaagtctt gcaaggaatc tgcttcaaga aatgataaaa
     2401 cagcattttc gttaacgttt gataactgta aattttgtaa acgagatttt gcttgatcga
     2461 agtaatcttc aataaccgct tcttgctgag aaatatctgc ttctgcttgt tcaatctctg
     2521 actctacatc cgcaattgtc gtgtcaagtt gagctagttc atcattcaag tcttcaattg
     2581 tttgaacaga tgaacgaact tgctgactta acgcttctaa gttagtttca gaatcggcta
     2641 ctttgtcttg agcttcttct gcgtaaacag actctactgt tgtaatagca cttggacctg
     2701 ttaataaagc taagactgat gctgttttta agatatgctt caatttcata atggatatgc
     2761 tccttattct atataatgat tgtgacatcg tacgtagtgt ctttcaatcg acatctatca
     2821 ttataacagg agaactccac tatttcagca atttctctta ttaaatgact agatatcagc
     2881 aatgtttttc ctttgttcct caatgttatg aatgtgtctc ttaaactttt taccgattta
     2941 ggatctaaac cgttgaatgg ttcatctaac acgataatat cagggtccgt caccagtgtc
     3001 atggcaattc ccaatctttg tctcatcccc attgagtatt tttttgtcgg catatcaata
     3061 aatttttcta acttgaactc atcgattaac cattcaatag atagatcatt attcttttgc
     3121 tcttctagct ttttaaataa atttaaatgc tccctcccac ttaaatacgg atacaaacta
     3181 ggctcttcaa tcaacacccc tatcgcttta tttgtcggtt gattgaaatg gatcacatga
     3241 ttttctatgc tcatttcccc actatctatt tttatttgag tggtcaaagc tttcattagt
     3301 gtcgtttttc ccgcaccatt atccccaaat aatccagtaa tcgcattgtt cttaatagct
     3361 aaatccatat tctcgagagc gttttttttt gccatatgtt ttattaacat ttttgaacgt
     3421 tatttgtttt tccatatttt atctcctttt tcaattgctt ctcattaaaa ttctttgcgc
     3481 tgatagactt tataactaat cacatagaaa acaatgacca acagcagtga gctacttgtt
     3541 gctataacca gaccaatccc ttctgataaa aactgtataa tttgaattag cttcgttaaa
     3601 taatttaaat tgagtaagat cggaaatacg accgttgcca taataaataa aatcactaat
     3661 atcacattta acaacttcaa cccaaagaca taataacagg tgtaatagaa ccctataaga
     3721 atcaaggcac ccgcaaatgt taacagtgct gtttgccaat ttaagtcaga aaataaaggg
     3781 acaattattt tactgccata tacagtcccc aacatcaatg cgacctctat catcgttgct
     3841 aaaaatttgc tagcgaccac catgcgccgg ctgaccggca aactattaat aaacacatcc
     3901 gcatcattta tgtcatcttc taatatactt gagtgcatca acgcaaacgt gaaggcaaat
     3961 aacgctactt gaatatgacc aaatatcgtg cctatcagga acaaaagagc aatataactg
     4021 acaaatgtct tccaattgaa agtcatctga aattctttaa agagtaaagc tttcatctta
     4081 taacctactt tctaccatca tttaatgcag ttgattgatt ctcatcgaag aacaccataa
     4141 tatcatctaa acttgccttc tcaatggtta ctagatcgtt aaataattca atcaatgtcg
     4201 ctgattctgt cgttaatccg gtaaagccaa cttgcttttc ttcaatggaa ataaacaagt
     4261 cacgaatgtc accatccaac agatcaacag gccccttgac caacttatag cgctctaaga
     4321 tattatattt ctcttcatca aaaataatct ccccatcctt aataaagata atataatccg
     4381 caattttctc tatatcttgt gtaatatgac tactgaagaa aattgttttg tcttcatctt
     4441 gtattaactc aaataaaaca tctaaaatat ggcgcctaac cacaggatct aaccccgatg
     4501 tcggctcatc aagaataatt aattctgcat gatgtgacag cgcgagagca agtgacaatt
     4561 ttgtcttcat tcccgtcgat aacttgtcta ccttactatc tagtggcaag ttgaattttt
     4621 ctatatattg gtcaaatata gcctggtccc acttcgaata aaagcgactg actaatttcc
     4681 caatttgtgc aaccgtctga gacttatata acacattttc tgcatagaca aagccgattc
     4741 ggtcttttaa ttgataattt tgttgagtca tctcttgacc aaaaatcgtc acccgtcctt
     4801 gatcagctcg caataattgc atcattaatt ttagtgtagt tgttttccct gagccatttg
     4861 ggccgataaa gcctgtaata tagccttttt tgatcttgag atttaattcc tttaatttaa
     4921 aatgatcaaa tgttttctct actccctgaa attctacaac gttctccatc tctcatcctc
     4981 caattcttat gtgtaacgtt acggtgtcat cactctatat ctaacccaca atcaacgtga
     5041 atttaagtat ctttttgact ctcctgctga aaagtttctt ccatcatctc caacaactcg
     5101 ggcaaggtga gatcaatgac ctgcgccgat tcgacaattt gagcgatgtc ttgctttatt
     5161 ttaatgattt gtttggtgcg aatagcatcc ggatttaatt ccgctacgta agttcccttg
     5221 cctgctatcg attcgacaaa ttgctcagcc tctaagcttt cataggcttt cttcgtagta
     5281 ataacactga cttctaactc cctcgctaac gctcggatgg aaggtaattg ttccccactt
     5341 gctaattctc cccgcagtat cgcctgtttc agttgtaatc taatttgttc atatatcgga
     5401 tcagatgact gcttggataa cacaatatga atcatcgctt gcctcctttt cccaaaaaaa
     5461 taatacccaa ctgtatatgt tgtacatgaa cagtatatac tcattggata aaatagtcaa
     5521 tttttattta tttttttcat taaaaattca aaatgtatta ctataaatat aaaagcatgg
     5581 taaacaagag ttaaccacag gagggtgaaa cgaacttaat gaaaaataga ctagcagaaa
     5641 accgttaggg ttgtcccaac atcgattagg taagaacatt gacgtctcaa gagaaagttg
     5701 ggaaaatatg aatgatcaaa ttgtaaatat aatactgacg ctggtgctag tctatctttt
     5761 tgctgcctat ataatttttc tggtgaaatc tgtcctttat ggaaaagaca aggtgtatgg
     5821 gtgtaagaag ccaacattag tacaaaaaat aaaagtaatt tttctattat aatgtaaatg
     5881 ctgtggctac agttgttttt ttaaatattc ttaaaatgct cccttcgaag tagacaataa
     5941 aaactacttc aaagggagca tatctttaag ttatttcaat ttaagcaatg tcgtccgcca
     6001 catcactcaa taatcgtatc taagaagtcc aattgtttgt gaatattgtc gcgggcttct
     6061 tttagccaga gttgtgcttc atagccgtga tacatacggt gcgggtaatt gtcgctataa
     6121 atattggact ggacataaat gtctttagca cgtaattgag ccacaagatc tgtcgcctgc
     6181 tgagtaaaag agactctatt cccgtccgac acataaaccg gcggataagc atcgttcaca
     6241 tgattaagca aattcgcctc tgctaacgta ttctccttca tgcggcttgg attcatatcc
     6301 atataagaaa agcccataac gctaaacagc caattaatta accaatgccc gacttgatta
     6361 gaacgcttcg ggtcaattaa ggcactattg agcataagtc ctcgaaacgt caatgtcgca
     6421 tgttgtctta agccaagtcg attagcatac gcactggatg attcaactaa ggctagctgc
     6481 cctgctaaat gcccgcccgc tgataaccct gccaacacga cattgtccaa atctaggcca
     6541 taacgctgac cttcactcgc gacaaagtcc attacgttac ttgcttgaat aataggcact
     6601 ggatacttat acgtgggggt taaggcataa ttagcggata tcacggcata tccttgcttg
     6661 acaaactcaa gcaaatatct tcgttcatcg atcttatcgc cccaagcaaa accaccacca
     6721 tgaaaataaa caatcactgg atacaaagct ggtcgtattt ccatatcatt ctcattatca
     6781 caagtgttct gttgctcttt tatccgattt tcttcgggag atcgcgtggg atgactcgaa
     6841 tgacttggaa taaagatatc taacttgtta tttggataat cactcttata ttcgacattt
     6901 ttatacacat tggcttgttt agccggtttt acacggcgac gtttcagacg ctgccgcatc
     6961 ttgctaaaca cacgcgttat gccaataact aagtccgccc aataatagcc aataatccag
     7021 ataataccca tgattgctaa taaactactg agtaacttcc ctaatttttt tactgtcttt
     7081 ttgatgcgta acgctcctca tatctcagtt actgtcttgg acaatttacg cctcgaacgg
     7141 gacagtctcc actgttaaat gcttatagtc cccaacaatt ttggcaaccg ggcaccgctt
     7201 gtgtgttgct tgaataatgg tttccgcttc gtctagtggg atatccgcta cagctgctgt
     7261 tagatctaag gtgaagtaat actcttcgct gacctcatct tgatgcaatt gcaccgtcac
     7321 ttgtacacgg ctcttcggct ctatctcccg ctctttcaat acggcatgca acgtcgcatt
     7381 aaagcacgtc gctaaggata atcccatcaa ttgttccgga ttagtccctg gctcatcact
     7441 cgtgggactg gacgtctgat acgactcacc gtccactaag taagactgcc catcaatacc
     7501 tgtctcattc actgcaacaa cttcatataa cataaatatg tcctcccttt ataaatatat
     7561 gaacaatata ccgttataaa atagttctca tatgtccatt atagcacgca caacagtgta
     7621 tttcatgtat aaaattgttc cttatttaaa taagatagca catatccaga atttaagctt
     7681 ttcactgatt acagtgacta attcagaaac ttatcctaca ttttttctcc cgcaacagaa
     7741 tagaggccca tataaaaaat ggacagaaat tatgacagct atgacggacc aataatatcc
     7801 attaaatcta taattatcta aaaaaatcac tataatatct attattctgc attagttttt
     7861 catgcttccc gtgtgctata atttttcctt tttttaatac ataaacacag tcagatatag
     7921 tagtggtaga aagtttatga gttaccgcta taatagtaat attttttttc tttaaattat
     7981 tgaaaatttc tctctctgta gatacatcta attgactggt cccctcatct aaaattatga
     8041 cctttgggtt agttaataat gctctagcaa tagccacccg ttggcgttga cctccagaaa
     8101 gatttctccc attatctcca atttctgtat tatatttaga tggcattctg ttcatcacat
     8161 cctcatctaa acaagcaagc tttgccgctt ctcttatttt tgagattgta tgactatgtg
     8221 tcggatcaat atttttttga attgtatcgt taagtaacgt ctcatcttgt aaaactgttc
     8281 cgaataactg ccggtatgat ttcaaatcat atacttcttt atctatatta tttaataata
     8341 tattcccttc aaaattatta tataaggata aaatcaattt tataatagtt gttttcccac
     8401 aacctgttct tcctacaaaa gaaataaatt ctccttcatt tatggtgaaa tttaactctt
     8461 taacattttt ttccattgat cccactgtat gagaagttaa catcttggaa tttaatattt
     8521 ttaaaactat ttatttctct tccatcaaaa tttttttcac ttttagctgt gataatctct
     8581 gaaagtctat ctatgttatt tttactatac tgaaaatcaa agatattttg tattaaaata
     8641 gctaatggac tcaataatgt atttcctaaa gctaaaaaag acataacttg accgagagtt
     8701 aacatcccct gattaacaaa gttactccct ataaataata cagtaacgct tggtaacaat
     8761 ctataggaga taattaaact cctgtacatc cctaataatc gctgcctttt aaattctaaa
     8821 tgcatttgtt cattataatt cttaacccat ttattatata gagcttcgcc ataatttgat
     8881 gttttcatca tattaatatt ggacgatagt tcaattaaat aactttgtgt cttttccctt
     8941 ttcattaatg atagtttatt tttacatctg tctttttaaa aaatatattt aacaacacac
     9001 acaacagtat cccgtatact atcataataa tcgataatat tcttgaaata tataacatca
     9061 ttgatataga tattactata gttaacacat ctacaaacac acccgtaatt atatttgata
     9121 acaattgttg aattgaatca atattattaa ttctagaaac aatatctcct gaagacctaa
     9181 catcaaaaaa agaaagtggt agataaaata atttacgcac tacatttttt ttttagagta
     9241 ctaatatatt ttatttctaa taatgttgtt aataattctc ttacaaaaga gaatacgccg
     9301 taagatagaa tagcaaataa tatcccaatt attaatttca catgggaaac taatgcaatt
     9361 ccatttatca cattatctat catatattca gtaaataagg gcattagcaa tacaaatagt
     9421 tgtattataa acgaaaaaaa tataacacca actataaatt tttttttaat ttctccaagt
     9481 gttaatattt caattatttt attttgggat ttttgttttt ttatattctc tggaaaaaac
     9541 aggagtaaaa tacccgtgaa ttttttcgaa aattcagaac catccattat tattctgcca
     9601 cattcaggat ctaaataata aattgttcct cttttagctt tttcaataac aacataatga
     9661 ctcattgata atacagcaat acatggaaat acaatctttt cagaaaaaat attttctttc
     9721 ttatttaatt caacagcctt agattttaat ccatattcat tcgctacatt cattaaatct
     9781 cttaagtgga caccatcacg agaaatagaa catttttcaa ctaaatcaga tatatgtagt
     9841 ttacacccat agtaatttaa taccattgtc agtgcagcaa ttccacagtc agattctgaa
     9901 agttgttgta caaattttat ttttttcaat ataatcccta ctttctaacc ctacctttta
     9961 tagttaccta aagtagaata gagctatata tattaaaatt ttattcaagt aataatataa
    10021 acggtaggtc ttcattcatt aaacttaata atccaaaccc tattcctgag agccccaaca
    10081 tcatacctgg agaattctta taaggaattc cgcactccca cttatctttt aattggctaa
    10141 tcagatgtga catataaata tcgtatcttt tgtctatatc atttttcgta ttcaattctg
    10201 atgatgcata ctttagaatt aacatatttc ccaaatctcc atgacacaaa cagtgactat
    10261 gtccaaatcc attttttaaa gtggttctaa cagcaatttc aatgtcttca tcaattttat
    10321 tttttctttt ttctgataaa ggtagattat gtttttttaa tgacgctcta cttaatagaa
    10381 ttccacttgc tccatgacac catgcaacgg gcatgttgga actcaagtta ttatattcaa
    10441 taccttcttc tgtttcacgt ctatcaaccc agtttttatc atcttcacta tataaataat
    10501 cttcatatct tagtgctttt tcaataactt ctatatatcg ttcatctggt aagtaagaat
    10561 acagtttcga taatgcccaa acaattccag aaacgccatg cgcaaaacct cccaatgcat
    10621 ttctcgaagc aatacctatc caagcaatgc tgttgttatc catctctata tagttatcaa
    10681 tgatttgttc tgcatactgt tgacacactt ctaaaatagc atcattagat gtcaaatcgt
    10741 aatatctcaa taaaatagct attacccctg atgaaccaat tataatatca tgctcatttc
    10801 caactgatat atttttctta cattctttga aaatccatga tcttattttt tctaattcat
    10861 ctaagtcaaa tattcctcct aattcttctt ctagtatcgt aagtgcgtat ataataggtg
    10921 tttcaccaga aaaaccacca aacataacct ctgaattaat atttgttctt tttctaacat
    10981 tttttatata atttataata cttttataac atctttttac catgattaaa tatttgtttt
    11041 gtttagtttc tttatacaga aatataaaat aaatcattat tcctgataat ccactgtata
    11101 aatccatact agtaggcacc atgttccaat cattagcttt ttctccaatt acattcatat
    11161 caatccaact aacatccccg ttcattccaa taaatgactg attaatcaaa taatcaccta
    11221 tattagtaga tatttctaaa agttgctggt ctaaatgatt tttatttaat ttgtcatcat
    11281 ttatctctat aatttttcta tcattttctc gctgggactc cgctttatta tattcagaat
    11341 cataattcaa agctgtttca atcaattcca cctgtaacgt caaatctttg tcccctaaaa
    11401 tatttatctt ttctttaacg agagcaatac tagagtgctt gaatatcgat tcaatttctg
    11461 aaccatcctt agtcgttata ttgtttttgc tgacatttga tattaaccac ggaatatcat
    11521 tctttaacaa agaagtaaac tctatttccg aaacttttct aaatgaatta ttttcatcaa
    11581 agtatatcca tagcttggaa aacaacattt ccctatcaat agcacttctc aaaaaatcag
    11641 gatgcaatga tatctggatt aatgttgtat aatattgtgt aggtcttaaa atttgtcttg
    11701 cataaatctc tttgtaattt tcaacttgat ttattatttc ttttttattt atgtttttaa
    11761 ttttagtgta tgattcaata aacccttttt tcaaatactt atgataactt gtaagactaa
    11821 tttcttctcc tattatatat gggttatttt tttgagatgc taacgtagat gtcttatatt
    11881 ctactttcat attatctttg tttacattag taatactggc ttgttctata ggaatttcct
    11941 tattctcact agttgatatg gcactaatat ctacaccgtt tttaccattt tgtgcccaaa
    12001 ctaaattagg taaaattcct actgtcctga cagaattctc taatagttca tttactctat
    12061 cagcagctgt atctatacca ctcgtatttg aagtattgtt atgaaataat gtctccaagt
    12121 ctatcaatac aggatgtttt ccttttgcaa taatattttc ataatgtata tcattcccac
    12181 gaagtagata aaacaaaaat aataattgtc ccaattcagt ataatagttt ttgaaatcac
    12241 tataatcctt acactcttcg tgtggaatat actctaccca accgtattca gtatgattta
    12301 tgatttttaa actatataaa tgacttttgg tcacttcatt gaaccattta attgtacttt
    12361 gaaaagttac atccattttt aaatctcttg gtttatagac aacagaagta ccttcctcaa
    12421 aatgaagtat aattacagtt tgtcctccat tgtgcacatc agaagtattc aattcaatac
    12481 tgtttaattc tccctcaatt ttaaaagttt ttctaaatca tctttatctg acaaaattct
    12541 atctataaat cgtgttgtat tatttatcca tttttgagtt gcctcacaca tcaacctgaa
    12601 cattacaggg tattcctcta aaatcaacca ataattatca cttaagtatt gagtcgaaaa
    12661 ataattatat ctttcctcag atgtttctcc tgctagtttg ttttcttctc tagctatatt
    12721 taattctaaa ataagagttc tatatgaaat ttcggctaat tggtcatata aatagattaa
    12781 taatttatta aatacattat ctgatatacc gggaatattt ttccaatagt tttcaaatct
    12841 taatatcgct aattttaaaa atggttcatg aaaaccataa aacattggta gttctttttg
    12901 cccaatatct cctattatat aaaattcagg taaaataata gattcaatgg aaaggacttg
    12961 taagtcgtga atcaattggt tccacaatac attcgtttca gtaactttgc atgagaaatt
    13021 atcattttcc gataataatt cgtttaaatt agctgtattt atccctaatc cattggataa
    13081 aatattctca atttctcttt cgttaacacc tagaaatttt ttccaatact gtaacctgtt
    13141 ttctgattta taattattag tctcatcatg ctgaatatct ctttcaaaag aatataaacc
    13201 atttttaaac ttatctatca atttcattca ttttacctcc cgaaaacagt attttcttct
    13261 ctatatgtac gcgaggagga aatacctgta gtacacctcc tcacacaatc ttattaacag
    13321 cacgctacag taaatactgg acattcagca gtaatcgtac aagcacgacc acatgaatgt
    13381 cttcctgaat aacaacgaca gtaagtatta gctgtacctg atgccattac tttatcaata
    13441 tcgtcactct tcaattctct gaaaatatct cctgctggat tatcgtagtc ctcttctttc
    13501 tcatatacag gtgtcttcca gttgttcact ttgttcttca taatatttcc tcctctcatt
    13561 taatttataa ataagcattt atgctatatt taccatgatt cttgttgtgc tattttttta
    13621 taaatgaaca ctgcacaaat tgctatcacg cacaaaataa caaccgatga actatactca
    13681 tatagatttg actccttaaa tcctgaaata ttaaataatg catttacagg gtataaatag
    13741 gatattgccg tttgttctat aaaaacactg acaaaagaac ttacaaaccc taccataaca
    13801 gctagttgca tattataatc catgtaaatt atgaccgaca aaattaacat tgcaatcaca
    13861 tacagaccat tagagtgcac gacatattca aataaatact ttaatacaat ttcctgagtt
    13921 aatatattac tgtgtatttt ttctaatact aatgtaaaca caaatatact tgatgtaaat
    13981 atcatactta caacccaaat aaatttagat ttattcaaaa ttaaatgact ttttcgaaca
    14041 ggaattgtta aaatatttat gtaaacacta ttctctcgct caattataaa agacgctgat
    14101 ccaattaatg tgaatactgg cagtagaaga taatacgtcc ccacaatcaa tgtattctgt
    14161 aaagtccatc cgggttcagc agcataaggg atgcccacat attttacatt acccattaga
    14221 tagtgaattc ctatattgag cactacaatc aaaattaaaa caataatcaa cttactccgc
    14281 ttcatttttt taaattctaa taccatctac aatacctccg aaagatcata actcttgctt
    14341 cttcaaaatt ttattcatgg caaaaagaac gatgattgta tagaaaatta tactaataac
    14401 cattagtgca atattgctat taacttcgac accttccata ctaccatacc aaattatatg
    14461 cggagctgta gccaaaggga taatcccgtt catgaaattt gttaaaaaga atgatgcaat
    14521 aatatacatg cttccaatta aattagttat aacaacattt ccctttgtgg ctacggatat
    14581 cagtgtaaca ggtagcattg ataaaaaaat cacaagtgaa gttaaaatac ataaccacag
    14641 ataccggaaa atcaatagcc atgtcatact aaatcgaaac cttgttacat acccaattac
    14701 acaaacactt atccaaatca ttaccatagc aacactcaaa acaatataaa tggcaattaa
    14761 tttagcggca attatttttt gtttggaaat tggaataacc gttaaatttt tcataacttc
    14821 attacgataa tcatctgaaa ttgtgctact actcaaagac aataaaataa atggtaataa
    14881 tagaaatcct gtataactta atgaaaattt gtataaatga ataaattgat caaataatcc
    14941 aactgcttgg gcagtgtaca ccgacatcat cgtaatataa atccctaata cgcttgcata
    15001 tacccacatt tgtttcattc gagttatttt tgttatctcc gtcgatacta aatctaacat
    15061 taaattacct cgtttctgtt acacgttgaa attgttcttc taatgtcaat ttctccctca
    15121 taattccctc gatatcgaca tcattttggg ttagtaattt atttacttca gatatatcca
    15181 tatctttaga aagcaatcgt actccttttg ctgtatttat catattatgt tggctaactc
    15241 ctgcttctaa taatactgat tttactttat caaaattaga tgtaaaaata tgaatagtaa
    15301 cttggctatt ttcattcatt ttttttagat ttatatattt aacaagctct ccctcatcaa
    15361 taatactcac ttcatctgct acttgttcca cttcagaaag aatatgacta gaaataagta
    15421 atgtttttcc ttgtcttttc atctctttac ataattctct aatttcaata acgcctgatg
    15481 ggtccaaacc atttgttggt tcgtccaaaa ttaagatatc cggatcatgc ataatcgcat
    15541 ttgcaatagc taatcgttgt ttcattccta aagaatattc tttgaatttt tttgaatctg
    15601 cgtatggaag atttactata gttaatgctt cttgtactgc ttgtttatct aactctctaa
    15661 gttttgcaaa aattgacaga ttttctgttc cagttaagtt agggtaaaaa cccggtgttt
    15721 ctatcataca accaacttgt ttcagaacat ttcttccttt ttccgtcaat tgattttctc
    15781 ctagaataaa tatacttcca ctagttggtt taattaagcc taatatactt ttcagtattg
    15841 ttgtttttcc agcgccattc ttcccaagta aagcatgaat agtcccttca actatattta
    15901 tattaattga tttaataaca gctacattgt cgtacgattt cgtcaaatta ttaatttcta
    15961 ttacgttttt catatagtac ataacacaaa agtgttactc actcctctca aatttaaatt
    16021 aagttaaaaa tttatatctt attcatggat tattagcaca aattgttata catatatacc
    16081 tgtcattaaa aatatttcct tttgacctta tcattaatct caacacttca ccaaattgat
    16141 atattacctt atgctctatc ctcacttatc ttaactactg tatataaatc aaaaaataat
    16201 atttttcact tgtgagtttc tcagttctaa aatacatatg aaagcgaata cttattaatg
    16261 attaaattgt accatattat ttaattgtat acaattttaa aactaaaatt tcacaaaaaa
    16321 atcacaaagt gcaaaaaata ccccaagtga cgtgctgttg tacgtcattc aaggagttgt
    16381 tagacattat caatagtcaa ttgcctcaga atatgcctct ataatcgtat ttaaaagtcc
    16441 aattgcttat tgatgttatc gagttcttct tcaagacgaa cgaagcatct agtacatggg
    16501 aaatgagtag cttggaatat tctcattttt tcatttaaat tggtcttacc acattatttg
    16561 agaaatcaca taattttatt tattagaaaa acaccacaac agatgtgtcg ataggagaag
    16621 ctgcctgtca tagcaactct cacgacaaca atcgatgtgg tatctataca tgtattatat
    16681 tattttatcg cgtgtagacg tcgaaccaac cagcgtgaca gcttgcgcac gtatcgtata
    16741 cttttccttg actgccgaat ggtgtatcaa taatcgttcc gtgaccgaca ctactgctgg
    16801 cagctaagac gatatagcct tcaccatcgc gaacgaatcc atctgctgtg tgacgaccag
    16861 gaatgttcaa tccgccaccg ggtaggacac gttctgaata gaacgtccat ttcttcccaa
    16921 gtgcattaat gaccccttga aattctaaat catcaattga atattgagca gttgttggga
    16981 cagctgcttg tggttgtatt ggttcttctt gtacttctgg ttctgtctgt gtttgtgatt
    17041 cttcttgcac ttgttggtca ggctgttttt gtgtctctgg ctctggttgt gattgttcag
    17101 cctctgccgg ttcagtttct gtcacttgag gttcttccac tgactgttca gctgccgaat
    17161 catcagttgg ttcagccggt tcttcgttct cttctattgc aacagtctct tcagcttgtg
    17221 gctgttgcgt ctcttctgct gattgacttg caacttgctt agcttcttca ttactagatg
    17281 cgtcttcctg aacttcttgc tcagcttgac gttcttcaac tagttcttca gcccgacgac
    17341 aaatctcaac tatctctgac tcttctttca acgtctcgaa atcttcgcga ttctcttcaa
    17401 ttaatctttc caagtcagct atttcagtat gaactgattg tttttttgcg tcaattgtct
    17461 cttttttgtt agaaagatct gtttgtttcg tttcaagtga ctgcactagt tggtcgagct
    17521 catctttttg tgcttgcagt gattgtattt gatctgaatt agcttgggtt aattgaacga
    17581 ccgcattaac gcgagcaatg atgtcttgga atgattcagc ttcaagaagt gataagacag
    17641 cattctcatt cacattagat aattgcatat tttgtaagcg tgatttagct tgatcgaagt
    17701 agtcctgaat gattgcttct tgctgggaaa tatcctcttc tgtttgtgcg atttctgctt
    17761 cgatgccatc aatcgtctca tcaatctgga caagttcatt attcaaatct tcaatcgtct
    17821 gaacagatga ccgaacttgt tgtcttaaat cttctaagtt agtttcagaa tctgctactt
    17881 tgtcttgagc ttcttctgca taaacatgat ctactgtcat agtagcactc ggtcctgtca
    17941 ataaagccaa aatggaggct gtttttaaaa tgtttttcaa tttcatagtt aagatgctcc
    18001 tcatctatat aattctatat aatgattaca tgattgaaca taatgtcttc caatcgacac
    18061 ctaccattat aacaggagaa ccgatctatt ctatgacagc tcgataacaa tttattacat
    18121 cccaactaca atatcggcca ccctttgtca tcggattgta aattttaggc aggaaacaat
    18181 cgataaccca ctccctacca acataaaaaa ccacaatcgc atcagaataa gtgctctctg
    18241 aatcaattgt gatgatttat ttattgacca aaaatacgaa atgccgcttt ataactgact
    18301 aaaatatttt cttcatcgtt attcgttaac gtgatggggc cttcgtacgg ttcaatttcc
    18361 gtaatttgat acgtttcgtt caactggatt cctttatccg tcaaataagt taaaaattca
    18421 gtatcatcat cgacttgttt caccttgaaa gattcacctt gtttgcactc tactaaagca
    18481 tgatattgat taacgatgac ttttccatct gaggttggaa tagtgtcccc gtgcggatca
    18541 actgtcgggt gtcctaagaa agcatctaag cgctcaatta acttatccga agaaatatgt
    18601 tccaataaat cagcatctgt atgcacttca tcccactcat aacctaattt ttctgccaag
    18661 aacacttccc atagacggtg gcgccgtatt aattgattaa caatacgaac ccctttatcc
    18721 gtcagtttta cccctttata aggttcatat gtaataattg attgcttcac caagcgcgta
    18781 ttcatatccg taatcgctgc agccgataca ttcaagtatt ccgccaaact cttattatta
    18841 atcagtttag acatgccacc tagttcgtaa atagccttta aaaaattctc cttatttggt
    18901 gtcatttctg tccccttccc ccattacttt ttttcattat acatgaaata gctcttaatg
    18961 cgtagtagag acatgagatc tttttaatta aatttttcag aaattagttt gaatgtcaaa
    19021 ttaaaatata gtatactatt cctagaaata atctaataaa gcaaaaggag ataataatga
    19081 gaactctaac aacaaaggat ttagtctata ttgccgtgct aacagctatg ctttgcgtat
    19141 catctttggt cgctattccc gttggtatcg gtattcccat tacattacaa gtctttttct
    19201 ggctacttat tcctgcatta cttaaagctt atcgtggatt tttaagccta gctctttatg
    19261 tattaattgg attgattggt attcctgtat ttgcaggagg aactggtggc tttcaagctg
    19321 ttctttctcc ttcatttggg ttccttcttg gttcgcttat catcgcttta tacattggga
    19381 aggtcgcaca gaaacgtccc tctctattaa caatgatttt acacatgatt gtggctattc
    19441 ttattttata tacgattgga attctttatc aatatttcat ttttaatgtc attgctgaat
    19501 caggcggttc tacgacactt atcagtctga ttattgccaa cgtttcatct ttcttaccac
    19561 tcgatattct aaaagctatc cttgccggta ttgtttatga ccgacttatc cgtcatactc
    19621 gcttcaaaaa catataaatt agtaaaagaa cgctactaag tacatagcgt tctttttttt
    19681 gctctattct aacaaaaaag caattgattc ataaggttgg agtacaagtt gttgctctag
    19741 cgcatgttgg tcataattac cgatcagtac tcgcgcatct tttttcaaaa aatctttcgg
    19801 tacatcaata gctgtctgct ttccataaaa attattaaat actagtactt gctgattgtc
    19861 atattcgcgc atataactat aaacatcagg atgatctaac tgaatactac gatatgttcc
    19921 ctctgatatc accgcataat ctttccgtaa tcgaatcaac tgcttataat aatccctgat
    19981 acgctgactc ggatcagtca catttgtatt gatatattta taattagaag caatttctaa
    20041 ccaaggttga cctgtcgtga agccagcttg gtcctcacta gtccactgca ttggtgtacg
    20101 actattatca cgcgattttg cttgaataat ggccaacgct tctgaattat tcatcccttg
    20161 tgccaaaagc gttctatatg cattatgtgt ttctacatca tcatattgat caatcgactc
    20221 ataatttgga ttggtcatac caatctcttc tccttgataa atataaggtg ttccacgtaa
    20281 taaatgaatc gttgttgcta gcaccgttgc tgattcgtac ggataattaa ctggatcagc
    20341 gaagcgacta ttagatcgtg gttgatcatg attgttccaa aataaagcat tccatccatt
    20401 gcccgcctgc attcctgttt gccaatgatc caataaacgc ttcaattcat caaaatcaaa
    20461 gtccatcaag gtccatttat ctccattttt atagtccacc tttagatgat gaaagctgaa
    20521 aaccatgtcc aatttatttg actcagaatg ggaatattgg acactattgg atacatccgt
    20581 cgaactcatc tcaccaactg ttatgatatc atcatatcgg ccaaaagtac gtttattcag
    20641 ctctcgcacc cactcatgaa caatcggcgt atctgtatat tcttttttcc ccacaccatc
    20701 agcagcatct tttagatctt gacttttacc aataacattg agtacatcga agcgaaaacc
    20761 tttaactcct ttgtcaatcc aaaaattaac cacatcatat aatgcttctc ttacctctgg
    20821 attatgccag ttcaaatcag cttgagtctt gtcatacaaa caaagataat aatagtcgct
    20881 atctcccaat tgattccaag cgggtccacc aaattttgac tcccaatttg tcggtaagct
    20941 tccatctggt tgtgcttgac gcaaaatgaa gtaatcttga tactgttctt cgccgttaag
    21001 tgctcgttgg aaccactcat gctctgttga aacatgattc aacaccatat cgagcattaa
    21061 gccaatatta tatttagacg cttcttggac aagtttgtca aaggtgtcaa aacctccata
    21121 cattggatca attgattgat aatctgctat atcataacca ttatcattct gaggtgattt
    21181 ataaaaggga tttaaccaca acaaatcaat gcctaaatca gctaaatacg gtaacttttc
    21241 aataatccct tgtagatcac ccattcctgt tccagttgta tccttccaag acttaggata
    21301 gacttgatag acaactttat catgaaaatt tttccccatg gtatcatcct ttctcctaaa
    21361 aagttccatg ataacctttt gatgcttatc atggaacttt ttattatcta tttctgctta
    21421 acttcctaat tttggaatcg gtagtccttc tagtttctga tcggttaaga cattatactt
    21481 ctcgaagata aagactagca cgaatggtac aaagaaggca attgccattg caataccgaa
    21541 attcaagtaa gaactattgg ttgcagatag aatcccaggc aatccgccga caccaatcgt
    21601 atacgctgcg gtgcttgtcg ctaccgagta cattcctgca aacgctgatc caatcatacc
    21661 cgccacaagt gggtagacgt atttaatatt aattccaaac aaagccggtt cagtcacacc
    21721 taaataagct gaaattgcag ctggtaatga cactgcactt tctttttcat tatgacggtt
    21781 cttccaccaa atagctaata ctgctgatcc ttgtgcaata ttggagaaag caatcattgg
    21841 ccacagaatt gtctgatcat actcagcaac tagttgtaag tcgatagcat tcgtcatgtg
    21901 gtgtagacct gtaacgacga acggtgcata caatccacca aagatgaagc caaataacca
    21961 attcaaggaa ccgctaagac cccactgtac cccgtccgct aaccacttac caagctgcca
    22021 accaatggga ccaatcaccg catgggcaat aaaaattgtg ggcactaaag caaagaatgg
    22081 cacaacaatc atcgaaatcg cttctggtgt aattttacgg aaaaatcgct ctagatatgc
    22141 aagcgtaaat ccggctaaca tcgcaggaat aacttgagct tgatacccaa tcatatcaag
    22201 ttgaaagaag ccaaagtccc attgttgtac atcaccagct aaaatttcct ccacaccgta
    22261 tgcatttaaa agttgcggtg atactaacgt aattcccaag acaattccta aaatttgagt
    22321 agtccccatc ttacgcgtaa ctgcccatgt aattccgacc ggtaagaagt ggaaaatagc
    22381 ttcacccggt aaccatagga aatgatttac cccattccaa aacgttgaca catcaacaat
    22441 tgtattatag atcggct
//
