LOCUS       NZ_JAGFWR010000021     21038 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Micromonospora antibiotica strain MMS20-R2-23 contig21, whole genome
            shotgun sequence.
ACCESSION   NZ_JAGFWR010000021
VERSION     NZ_JAGFWR010000021.1
KEYWORDS    WGS; RefSeq.
SOURCE      Micromonospora antibiotica
  ORGANISM  Micromonospora antibiotica
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 111393)
  AUTHORS   Lee,D.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2021) Microbiology & Molecular Biology, Chungnam
            National University, 99, Daehak-ro, Yuseong-gu, Daejeon 34134, South
            Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 79.63x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017599305.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 02:05:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,561
            CDSs (total)                      :: 6,498
            Genes (coding)                    :: 6,378
            CDSs (with protein)               :: 6,378
            Genes (RNA)                       :: 63
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 20 of 120
            Pseudo Genes (incomplete)         :: 107 of 120
            Pseudo Genes (internal stop)      :: 2 of 120
            Pseudo Genes (multiple problems)  :: 9 of 120
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:14:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 17718
            Orig. end                         :: 38756
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAGFWR010000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21038
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21038
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21038
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11038](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11038
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    116..125
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(399..1385)
                     /locus_tag="JQN83_RS25480"
                     /old_locus_tag="JQN83_25475"
     CDS             complement(399..1385)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014690241.1"
                     /locus_tag="JQN83_RS25480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25475"
                     /product="aldo/keto reductase"
                     /protein_id="WP_208569695.1"
                     /transl_table=11
                     /translation="MIRRQLGADGPEVSAIGLGCMGMSFAYGGPDDAESTRTLHRALDL
                     GVNHLDTADMYGFGANERLLAPVVRARRDEVFLATKFGNRRTPDGSGVRVDSSAAWARE
                     ACDASLGRLGVDTIDLYYLHRRDPGTPIEETVTAMAELVEAGKVRRLGLSEVSPATLRT
                     AHAVHPISAVQMEYSLFTRDVEGEMLDTCRELGVALVAYSPVGRGLLTGAITGRDQLAE
                     GDWRAAAPRFAAESLDANLRLVAAVRAVADEIGCTPAQAALAWLLAQGPDVLPIPGTKR
                     VRYLEENTAAADLRLTAAQQARLREAVPADAVAGERYAAAGMRTVGH"
     gene            complement(1382..1768)
                     /locus_tag="JQN83_RS25485"
                     /old_locus_tag="JQN83_25480"
     CDS             complement(1382..1768)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011208836.1"
                     /locus_tag="JQN83_RS25485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25480"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_208569696.1"
                     /transl_table=11
                     /translation="MDISTRERVLSVGEAAARVGLTTYTLRWYEQEGLVAPVGRDSAGR
                     RRYTEADLNWLMLLTRLRRTGMPVRDMRRYAELARQGDRTRAARRALFEAHRVRVLTRM
                     AELEEDLKVLNYKIEIYRCAEEGR"
     misc_feature    1779..1793
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.04"
                     /tool="antismash"
     gene            1874..2614
                     /locus_tag="JQN83_RS25490"
                     /old_locus_tag="JQN83_25485"
     CDS             1874..2614
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072125.1"
                     /locus_tag="JQN83_RS25490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25485"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_208569697.1"
                     /transl_table=11
                     /translation="MDDAIAVRDLVVDRGRRRVLDGIGCTVPRGAVTGLLGPSGSGKTT
                     LMRAVVGVQTINSGTVTVLGRPAGAAELRRRVGYLTQAPSVYVDLTVRENARYFAALQG
                     RTVADADAAVTDVGLAAAAGQLVGTLSGGQRSRASLACALVGEPELVVLDEPTVGQDPV
                     LRADLWARFHALAAAGTTLLVSSHVMDEAARCDRLLLIRHGRLIADDTPDAVRAATGVD
                     DLEEAFLRLIRAGEAGPADIGEAA"
     gene            2611..3366
                     /locus_tag="JQN83_RS25495"
                     /old_locus_tag="JQN83_25490"
     CDS             2611..3366
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014389.1"
                     /locus_tag="JQN83_RS25495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25490"
                     /product="ABC transporter permease"
                     /protein_id="WP_208569698.1"
                     /transl_table=11
                     /translation="MNPTILAATTGRILRQLRHDRRTVALLVVVPTVLLTLVYYMYADQ
                     PAPPGRPSPFDRVALVMLGFFPFIIMFLVTSIAMLRERTSGTLERLLTTPLGKLDLLFG
                     YGIAFGLAGVVQSTVAAAAAYRLLGLTTAGSAALVVLIAAVNAVLAVALGLLCSAFART
                     EFQAVQFMPVVVAPQLLLCGLFVPRDQMAGWLQTVSDALPLSYAVEALQEVGAHSTPTG
                     LMWRDVSIVAGAAVVALVLAAATLRRRSG"
     gene            3372..3965
                     /locus_tag="JQN83_RS25500"
                     /old_locus_tag="JQN83_25495"
     CDS             3372..3965
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462936.1"
                     /locus_tag="JQN83_RS25500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25495"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_208569699.1"
                     /transl_table=11
                     /translation="MTRRTGRRPGNQDTREAILTAARSAFAERGFDAASIRQVATAAGV
                     DPALVHHYFGSKEELFRATVDIPVDPAALLPAVLAGDPDGIGERLVRTFLGVWDSPAGG
                     AAVALLRSASNNEWTARLMREFLTTQVLRRVLDQLDLDPAERPLRGALVATQMIGLAMM
                     RYVIRLEPVASATPDTLAATLGPTIHRYLTAPLP"
     gene            complement(4123..4860)
                     /locus_tag="JQN83_RS25505"
                     /old_locus_tag="JQN83_25500"
     CDS             complement(4123..4860)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462938.1"
                     /locus_tag="JQN83_RS25505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25500"
                     /product="DUF2470 domain-containing protein"
                     /protein_id="WP_208569700.1"
                     /transl_table=11
                     /translation="MAPTPAELIRTLVAGRLPGLVHLAHRPGPFHVRHATDVEGRVLLL
                     VPVFSDLAAELDPGVARDVAVVLDVLDLPPAAGAPSAGRAWVSGWAVPLDGESARRAAV
                     DFAAVDPTGDLLDVGSRFRLHRFEVVEARLETAGVVHRVDPGEYAAAEPDPLHADEAAL
                     LADLANHHGPETVAYLRGRLRLTGDEPRVVRLDRYGLVVAYGRPGDRRRTRLPFPHPVT
                     DPADLPHLLHPLLHLPTPAHPHP"
     misc_feature    complement(4872..4887)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.29"
                     /tool="antismash"
     misc_feature    complement(4875..4893)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 30.03"
                     /tool="antismash"
     misc_feature    5065..5079
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            complement(5104..6891)
                     /locus_tag="JQN83_RS25510"
                     /old_locus_tag="JQN83_25505"
     CDS             complement(5104..6891)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462941.1"
                     /locus_tag="JQN83_RS25510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25505"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_307799712.1"
                     /transl_table=11
                     /translation="MSANVGGGDERVEGTWQTLRRGLALSPELRTGLAGTIALALVYMV
                     GRVAVPVAVQRGIDQGIAVPGGPDLGVIVTVVTATTAVLVVTTACGYLMMRRLFTVSET
                     ALANVRTRAFRHVHDLSMLHQQSERRGSLVSRVTSDVDQITHFLQWGGVILLVNLGQLA
                     VTTAVMLAYSWQLTLVVLVAFTPAVLMIRLLQRRLAGAYGVVRQRMGTLLGTIAESVVG
                     APVIRAYGVSGRTARRLDEAIDGQRVAQQRAIRISIMGSSVGELAAGVALAGVVVVGVS
                     LGVDRTLSVGQLTAFLFLVTLFIQPVQIATEVLNEAQNAIAGWRRVLDVLDIAPDVADP
                     GEQGRELPAGPLDIRFAGVTFAYPGGPPVLHGVTLDIAAKSRVAVVGETGSGKTTFAKL
                     LTRLMDPTQGRVLLSGVPLDEVRFDSLRSRVVMVPQDGFLFDATVGENVRFARPELTDA
                     QLTAAFTELGLADWLDGLPAGLATAVGERGEALSVGERQLVALARAYVADPDLLVLDEA
                     TSAVDPATEVRLQRTLDAVTRGRTTLAIAHRLSTAQAADEVVVVDRGRIVQRGPHEELL
                     RDPDSVYGLLYASWLEQTR"
     gene            complement(7066..8940)
                     /locus_tag="JQN83_RS25515"
                     /old_locus_tag="JQN83_25510"
     CDS             complement(7066..8940)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020215714.1"
                     /locus_tag="JQN83_RS25515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25510"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_208569701.1"
                     /transl_table=11
                     /translation="MASGTSRDVIHRGLWVLGRAIREQPRIFAVAVAGSVLFGGLVIVS
                     AYVVGAVVGDVVVPAIESGEVGTSTLALAAVALFGISVLRVVGIFGRRLGAGYMQFRLQ
                     AAYRRRVTRRYLELPLSWHHRNSTGTLLSNANSDVEAAWYPIAPLPFAVGTLVMLVGAV
                     GSLFVTDWALALVGLAVFPALFALNVVYSRRMAPRQARAQRLRAEVSGIAHESFDGALV
                     VKTMGREAQETARFAGRAHELRDSLISVGRLRGVFDPLLETLPSLGTLAVLVVGTIRLR
                     QGAITVTELVSVAFLFTVLAFPVRAIGWVLAELPRSVAGWDRVRRVLDATGEMPYGDGT
                     LADDATPATLAFDGVHFGYEPAEAHLPGTSVLGEVAFTVPAGRTVALVGPTGAGKSTIA
                     SLAVRLVDPDAGTVTLDGVDVRRLTAASLASTVALVAQVPFVFDDTVRANISLDRPGID
                     DEDVWAALRLAEADGFVAALPDGLDTMVGERGTSLSGGQRQRLTLARALAGRPRLLVLD
                     DATSAVDPRVEAAILAGLRAPAPGQPAAASILVVAYRRATIALADEVIYLEQGRVLARG
                     THTELLASVPGYVDLVTAYEQAEQEREQNRTYDEVAPLPSGLEIEVDR"
     gene            9158..9787
                     /locus_tag="JQN83_RS25520"
                     /old_locus_tag="JQN83_25515"
     CDS             9158..9787
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183502.1"
                     /locus_tag="JQN83_RS25520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25515"
                     /product="TIGR03085 family metal-binding protein"
                     /protein_id="WP_208569702.1"
                     /transl_table=11
                     /translation="MPRYARAEREALADLMLEVGPDAPTINEGWTARDLAAHLVVRERR
                     PDAAGGILLPPLHGYAERVRLRTAARPWPELVDQVRRPPVWSPVSNPLTDELANTMEFF
                     IHHEDVRRARSGWHPRDLPAGLAARLWKPVALLTRTRARRFPASLLVQAPGHGEVATGR
                     GGDRVRLVGSPGELVLFLSGRQRVARVQLDGPPALTERLRTAQLGM"
     misc_feature    complement(9931..9944)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    9931..9945
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            10001..11038
                     /locus_tag="JQN83_RS25525"
                     /old_locus_tag="JQN83_25520"
     CDS             10001..11038
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287567.1"
                     /locus_tag="JQN83_RS25525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25520"
                     /product="terpene synthase"
                     /protein_id="WP_208569703.1"
                     /sec_met_domain="T1TS (E-value: 1.2e-68, bitscore: 225.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSFDVSALLEPPFVSRRHPATDAVAAASLEWAHRQGLVGAGRSA
                     GRLHRAGAAELAGRACPQASVAHLRLLTDLFSWLFVMDDVCDDDGLGSTPATLAPTVAA
                     LLDVLDRHGAPTSRGTPTGRYAPTGQGTPTGQGTPTGQDAPTGRGAPGGALGAALADLC
                     RRVRDQRRPALLLRLVGQLRAYLLALLWEAANREHRRVPGVAEYRQMRRHTGAVRPSLA
                     LTDLAYGRPPGARRRVDPALVALDDLAVDLVCWCNDLFSYRKEQGPVADPHNLVTVLAA
                     QTGRGEADAFRLAAGWFNDGLAGYLVREAALVAHGGPALTPYLAARRSWLRATYDWSAR
                     ADRYA"
     misc_feature    complement(11170..11185)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            11214..13040
                     /locus_tag="JQN83_RS25530"
                     /old_locus_tag="JQN83_25525"
     CDS             11214..13040
                     /NRPS_PKS="Domain: AMP-binding (13-471). E-value: 3.3e-92.
                     Score: 301.1. Matches aSDomain:
                     nrpspksdomains_JQN83_RS25530_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475807.1"
                     /locus_tag="JQN83_RS25530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25525"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_208569704.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-91, bitscore:
                     299.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALDIPYRSIPDMFRKRVAATPDQHAFAHPAPDDSGPVWLTWAQV
                     GRRADAVAAGLHGLGVGLEDPVAILANTRLEWIIADFGIMCAGGATTTVYPTTEPQDAA
                     YIIADSGSRVLFAENPAQAAKVAGTQLPALTHVVLFDGTPDPAAAVPQLTLAELEEQGA
                     QALAADPGLVDRLIAPVGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVVQAETGLLR
                     DDDVQYLWLPLSHSFGKTLLCGSTHVGLPTYVDGRVDKLVELLSVIRPTLMCGAPRVYE
                     KVYNKAVTTAQDAGGAKAKIFAWAVAVGKEKIALEQAGRPVPGGLKLRYAVAEKLVFSK
                     LQARLGGRIRVLVSGAAPLSAEIATFFAAANLPISEGYGLTETSAGNFVNPPDGLRIGT
                     VGRAMGDLECRIDTDGEILVRGRPVMRGYHNLPEETAAAFTEDGFFRTGDIGSLDDDGY
                     LRITDRKKDLVKTSGGKYVAPSHIEGMFKAICPYTSQAIVIGQARNYCTMLVSLDPDAI
                     RGWAAGGPLDGRDYAEIVASPEARAMVEEHVAQLNTKLNRWETIKKVTVLPRDLTIEDG
                     EMTPSLKIKRRGVESNFAAEIDRMYAGSLAEI"
     aSDomain        11253..12626
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JQN83_RS25530_AMP-binding.1"
                     /evalue="3.30E-92"
                     /label="JQN83_RS25530_AMP-binding.1"
                     /locus_tag="JQN83_RS25530"
                     /protein_end="471"
                     /protein_start="13"
                     /score="301.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FRKRVAATPDQHAFAHPAPDDSGPVWLTWAQVGRRADAVAAGLHG
                     LGVGLEDPVAILANTRLEWIIADFGIMCAGGATTTVYPTTEPQDAAYIIADSGSRVLFA
                     ENPAQAAKVAGTQLPALTHVVLFDGTPDPAAAVPQLTLAELEEQGAQALAADPGLVDRL
                     IAPVGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVVQAETGLLRDDDVQYLWLPLSH
                     SFGKTLLCGSTHVGLPTYVDGRVDKLVELLSVIRPTLMCGAPRVYEKVYNKAVTTAQDA
                     GGAKAKIFAWAVAVGKEKIALEQAGRPVPGGLKLRYAVAEKLVFSKLQARLGGRIRVLV
                     SGAAPLSAEIATFFAAANLPISEGYGLTETSAGNFVNPPDGLRIGTVGRAMGDLECRID
                     TDGEILVRGRPVMRGYHNLPEETAAAFTEDGFFRTGDIGSLDDDGYLRITDRKKDLVKT
                     "
     CDS_motif       11769..11828
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JQN83_RS25530_0001"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="JQN83_RS25530"
                     /protein_end="205"
                     /protein_start="185"
                     /score="23.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGRPKGVELLH"
     CDS_motif       12456..12530
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JQN83_RS25530_0002"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="JQN83_RS25530"
                     /protein_end="439"
                     /protein_start="414"
                     /score="26.8"
                     /tool="antismash"
                     /translation="GEILVRGRPVMRGYHNLPEETAAAF"
     gene            complement(13099..14403)
                     /locus_tag="JQN83_RS25535"
                     /old_locus_tag="JQN83_25530"
     CDS             complement(13099..14403)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072131.1"
                     /locus_tag="JQN83_RS25535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25530"
                     /product="low temperature requirement protein A"
                     /protein_id="WP_208569705.1"
                     /transl_table=11
                     /translation="MGSPQWSRGVRLGAPGSRTTRLELFYDLVFVFAFFNVTALTSQQP
                     TGTNLLRCLLVLGLLWWCWTGFAGVGNVVRADQGLLPVVGFVTIAATFLLALSMPGAFN
                     DRPGGLNGPLVFVGCYLLVRACQLAVFGLLARGEAARWRQWRRLAVLPVVAAALLVASA
                     LLPNRISGDGAATALQLTLWTAALLLEYAAGVRLGGTYWVVVSAGHWAERHALMVLIAL
                     GESIIALGVGPKFVTGLPLTWPVVIAAVLGIAVASVLWWAYFDTLALALEQALHRSRDP
                     AHRARLARDAYTYLHLPIVAGVIFFALGLKDLLTEVADPDNPDWGVPLGGYWVLVLYGG
                     VSLYLLSLVACGLRALRVLRWPPVLAVLALAALAPVGARVSEVGALALLALVCVALVVV
                     ETRGQGRRRHRVRQLALAEQEAAEAEQSRWRREHL"
     gene            complement(14485..15942)
                     /locus_tag="JQN83_RS25540"
                     /old_locus_tag="JQN83_25535"
     CDS             complement(14485..15942)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (126-462). E-value:
                     2.4e-28. Score: 91.2. Matches aSDomain:
                     nrpspksdomains_JQN83_RS25540_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014395.1"
                     /locus_tag="JQN83_RS25540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25535"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_208569706.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.8e-28, bitscore:
                     91.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQVRGVQLARLLGQWHALPGRRRSPDYAALAAAVRGLLADGRL
                     PLGVRLPAERELAEALRISRTTVTAAYRQLRETGHLASRRGAGSWTMLPGTHRVASTGL
                     WTPLDDRDMIDLGVAALAAPPELVPAARAALEDLPRYLSGAGYHPTGIIELREAVARAY
                     TERGLPTSAEQIMVTSGTQHALDLVLRLALAPGGNVLVESPTYPNALAALAARRARIST
                     HGLAVDAGWDADLLLGSVRQTRPKLAYLIPEFQNPTGHLMPAELRERLVATAHAAGTDL
                     VVDESFVDLPLDGTPLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAPQVQRLA
                     AARVGVDMASPVLDQLVAVHLLAQAPAIVAARRAQLVTQRDALLDVLAERLPDWRVGVP
                     RGGVTLWVELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPAADLVEA
                     VGRLAAIRYDLDRGAGRARWREPAVIA"
     aSDomain        complement(14557..15564)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JQN83_RS25540_Aminotran_1_2.1"
                     /evalue="2.40E-28"
                     /label="JQN83_RS25540_Aminotran_1_2.1"
                     /locus_tag="JQN83_RS25540"
                     /protein_end="462"
                     /protein_start="126"
                     /score="91.2"
                     /tool="antismash"
                     /translation="LVPAARAALEDLPRYLSGAGYHPTGIIELREAVARAYTERGLPTS
                     AEQIMVTSGTQHALDLVLRLALAPGGNVLVESPTYPNALAALAARRARISTHGLAVDAG
                     WDADLLLGSVRQTRPKLAYLIPEFQNPTGHLMPAELRERLVATAHAAGTDLVVDESFVD
                     LPLDGTPLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAPQVQRLAAARVGVDM
                     ASPVLDQLVAVHLLAQAPAIVAARRAQLVTQRDALLDVLAERLPDWRVGVPRGGVTLWV
                     ELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPAADLVEAVGRL"
     gene            16001..>16651
                     /locus_tag="JQN83_RS25545"
                     /old_locus_tag="JQN83_25540"
                     /pseudo=""
     CDS             16001..>16651
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019868867.1"
                     /locus_tag="JQN83_RS25545"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25540"
                     /product="YitT family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MALIGNLRHRPARRLTQLYAGLVLYGVSMAMMIRSGLGLDPWDVF
                     HQGLARQTGLSFGTVTIAVGAVVLLLWIPLRQRPGLGTISNVLVIGLVVDATVALLPAG
                     WPLPARIGLLLGGIVANGAATGLYLGARLGPGPRDGLMTGYVARRPGRSVRLVRTVIEI
                     TVLALGWLLGGTVGVGTVAYALGIGPLAQFFIPRFAVPAEPVHPEPVHPEPDPG"
     gene            17023..17481
                     /locus_tag="JQN83_RS25550"
                     /old_locus_tag="JQN83_25545"
     CDS             17023..17481
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785229.1"
                     /locus_tag="JQN83_RS25550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25545"
                     /product="hypothetical protein"
                     /protein_id="WP_208569707.1"
                     /transl_table=11
                     /translation="MGENAWRWTDAWIFVSLVIASGAGRHRRAADSRRPEGVRLTDVLS
                     TADHLNQAIPERHDVETAVQRLVGAGLVTVSDGWFRITPDGEQLWRTRPRAGVGGTVDS
                     MQGVLTRRHAPGSAQWHLPEEDHAAAVQEYVVRSIPAPRRSPEGQTGR"
     gene            complement(17683..18450)
                     /gene="hisF"
                     /locus_tag="JQN83_RS25555"
                     /old_locus_tag="JQN83_25550"
     CDS             complement(17683..18450)
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019900882.1"
                     /locus_tag="JQN83_RS25555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25550"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="WP_208569708.1"
                     /transl_table=11
                     /translation="MTVAVRVIPCLDVDAGRVVKGVNFLDLRDAGDPVELAAAYDRAGA
                     DELTFLDVTASSSDRGTMLDVVRRTAESVFIPLTVGGGVRQVADVDTLLRAGADKVGVN
                     TAAIARPELIAEIADRFGRQVLVLSLDVRRAPAGTTPSGFEVTTHGGRRGTGLDAVEWA
                     ARGAELGAGEILLNSMDADGTKAGFDLTLIEAVRAVVDVPVIASGGAGRVAHFPPAIGA
                     GADAVLAASVFHFGELTVGEVKDALRTAGHPVR"
     gene            complement(18644..19642)
                     /locus_tag="JQN83_RS25560"
                     /old_locus_tag="JQN83_25555"
     CDS             complement(18644..19642)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (19-330). E-value: 5.4e-19.
                     Score: 60.4. Matches aSDomain:
                     nrpspksdomains_JQN83_RS25560_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072136.1"
                     /locus_tag="JQN83_RS25560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25555"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_208569709.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.5e-24, bitscore:
                     79.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNREIHLASRPQGWPTADNFRLVETEVPTPGPGQIVVRNQFMS
                     VDPYMRGRMNDVKSYVPPFALDEPLDGGAVGEVVAGGADGISVGDTVLHGLGWREYALL
                     DGRSARRVDPDVGPVSAYLSVLGMTGLTAYAGLLDVAAMRPGETVFVSGAAGAVGSMVG
                     QIAKLRGAGRVVGSAGSPAKVARLTELGFDAAFDYHDGPVRDALKAAAPDGVDVYFDNV
                     GGEHLEAAIGAMNLHGRAAICGMIAQYNSAEPPAAPRNLALVIGKRLTLRGFLVGDHGD
                     LREQFVTEVAGWLREGRLSYDETIVDGLDNAPDAFLGLLRGENLGKMLVRL"
     aSDomain        complement(18653..19585)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JQN83_RS25560_PKS_ER.1"
                     /evalue="5.40E-19"
                     /label="JQN83_RS25560_PKS_ER.1"
                     /locus_tag="JQN83_RS25560"
                     /protein_end="330"
                     /protein_start="19"
                     /score="60.4"
                     /tool="antismash"
                     /translation="DNFRLVETEVPTPGPGQIVVRNQFMSVDPYMRGRMNDVKSYVPPF
                     ALDEPLDGGAVGEVVAGGADGISVGDTVLHGLGWREYALLDGRSARRVDPDVGPVSAYL
                     SVLGMTGLTAYAGLLDVAAMRPGETVFVSGAAGAVGSMVGQIAKLRGAGRVVGSAGSPA
                     KVARLTELGFDAAFDYHDGPVRDALKAAAPDGVDVYFDNVGGEHLEAAIGAMNLHGRAA
                     ICGMIAQYNSAEPPAAPRNLALVIGKRLTLRGFLVGDHGDLREQFVTEVAGWLREGRLS
                     YDETIVDGLDNAPDAFLGLLRGENLGKMLV"
     CDS_motif       complement(19163..19207)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JQN83_RS25560_0001"
                     /evalue="9.00E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="JQN83_RS25560"
                     /protein_end="160"
                     /protein_start="145"
                     /score="8.9"
                     /tool="antismash"
                     /translation="GETVFVSGAAGAVGS"
     gene            complement(19689..20120)
                     /locus_tag="JQN83_RS25565"
                     /old_locus_tag="JQN83_25560"
     CDS             complement(19689..20120)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072137.1"
                     /locus_tag="JQN83_RS25565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25560"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_244253193.1"
                     /transl_table=11
                     /translation="MQVLYTASATATGDGRDGHVRTSDSTLDLDLAIPKEMGGAGGAAN
                     PEQLFAAGYAACFHSALRVVARRAKADVTGSVVEAEVGIGANGSGGFGLAVTLVVDLPA
                     VERAAAQQLVEAAHQVCPYSNATRGNIEVALTVREAAAA"
     gene            complement(20126..20572)
                     /locus_tag="JQN83_RS25570"
                     /old_locus_tag="JQN83_25565"
     CDS             complement(20126..20572)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018789360.1"
                     /locus_tag="JQN83_RS25570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQN83_25565"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_208569711.1"
                     /transl_table=11
                     /translation="MSDHLVLRDQVCFALYAASRALTDVYRPILDEFGLTYPQYLVLLV
                     LWERGDDPPTVSELGTALRLDSGTLSPLLKRLAAAGLVVRTRSALDERRVEVGLTADGV
                     ALRQRMTDVPLRVACSTGLDEAELVALRDTLTRVTETIHRQKEQ"
     misc_feature    complement(20553..20568)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.28"
                     /tool="antismash"
ORIGIN
        1 cgaggtcgac gtcactgtag gcggtggcgg ctgaccgggc atggctgccg cgcagcagaa
       61 tcccgaccac cggacgctcg gcggaggccc gtaaccggtc ggtccagtcg gccaggaagg
      121 cggcctccgg caacggagcg tgatccaccg cgccatcgtg ccgtacgtcc gatcaggtcc
      181 gcaatgcccg aaggcggaca tcctgtccgg tcagaaggct agcgcccggt ccgaaggctg
      241 aagcccgggt cggggctaaa gaccggtaat aaggctagcg cccgatccga tggtagggcc
      301 gcaggtgctg acggtcgcct gagcgcgcgg cccgatccgg acaccggccg aggtgaccgg
      361 atcgggccgt tcgcggcgag agaggcgacc ggcgcaggtc agtggccgac cgtccgcatc
      421 ccggctgccg cataccgctc gccggccacc gcgtcggcgg ggaccgcctc ccgcaaccgg
      481 gcctgttggg cggcggtgag ccgcaggtcg gcggcggcgg tgttctcctc caggtagcgg
      541 acccgcttgg tgcccgggat cgggagcacg tccgggccct gggcgagcag ccaggccagg
      601 gcggcctggg ccggcgtgca gccgatctcg tcggccaccg cccggacggc ggccaccagg
      661 cgcaggttgg cgtcgaggct ctccgccgcg aagcggggag ccgccgcccg ccagtcaccc
      721 tcggcgagct ggtcccgccc ggtgatcgcc ccggtgagca gccctcgccc gacgggtgag
      781 tacgccacca gggccacccc caactcccgg caggtgtcca gcatctcccc ctcgacgtcc
      841 cgggtgaaca gggagtactc catctgcacg gccgagatcg ggtgcaccgc gtgggccgtg
      901 cgcagggtcg ccgggctgac ctcggacagg ccgagccggc gcaccttgcc cgcctcgacc
      961 agctcggcca tcgccgtgac ggtctcctcg atcggggtac ccgggtcacg gcggtgcagg
     1021 tagtacaggt cgatggtgtc gaccccgagc cgcccgaggg aggcgtcaca ggcctcccgg
     1081 gcccaggccg cgctgctgtc gacgcggacc ccggagccgt cgggggtgcg tcggttgccg
     1141 aacttggtgg ccaggaagac ctcgtcgcgg cgggcccgca ccaccggggc gagcagccgc
     1201 tcgttggcgc cgaagccgta catgtcggcg gtgtcgaggt ggttcacccc caggtcgagg
     1261 gcgcggtgca gggtgcgcgt cgactccgcg tcgtccggcc cgccgtaggc gaagctcatc
     1321 cccatgcagc ccaggccgat cgcggagacc tccggaccgt cggcccccag ctgtcgacgg
     1381 atcatcgccc ctcctccgcg caacggtaga tttcgatctt gtagttgagc accttgaggt
     1441 cctcctccag ttcggccatc cgggtcagta cccggacccg gtgggcttcg aacagcgccc
     1501 gtcgggcggc ccgcgtccgg tcgccctggc gggccagctc ggcgtaccgg cgcatgtcac
     1561 gcacgggcat cccggtgcgg cgcagccggg tgagcagcat cagccagttc aggtcggcct
     1621 cggtgtagcg gcggcggccg gccgagtcgc ggccgaccgg ggcgaccagc ccttcctgtt
     1681 cgtaccagcg cagtgtgtag gtggtcaggc cgacccgggc cgccgcctcg ccgaccgaca
     1741 ggactctctc ccgcgtgctg atgtccacgt gccccaggtt ctcagttcga gcgtgctcga
     1801 agtcaaccgt tgcgccacac cgggtaattc atctagcgtt gatttcaaca tacgatgagt
     1861 tttgggaggc gcgatggacg acgccatcgc cgtccgcgac ctggtcgtcg accggggtcg
     1921 acgacgggtg ctggacggca tcggctgcac ggtgccgcgc ggcgcggtca ccgggctgct
     1981 cggcccgagc ggcagcggca agaccaccct gatgcgggcc gtggtcgggg tgcagacgat
     2041 caactcgggc acggtcaccg tgctgggtcg accggccggt gcggccgagc tgcgccgccg
     2101 ggtcggctac ctgacccagg cccccagcgt ctacgtcgac ctgacggtcc gggagaacgc
     2161 ccgctacttc gccgccctcc aggggcgtac cgtcgccgac gccgacgcgg cggtcaccga
     2221 cgtcggcctg gccgccgccg ccggccaact ggtcggcacc ctctccggcg ggcaacgcag
     2281 ccgggcctca ctggcctgcg cgctggtcgg cgaaccggaa ctggtcgtcc tcgacgagcc
     2341 caccgtcggg caggacccgg tgctacgggc cgacctgtgg gcccggttcc acgccctggc
     2401 cgccgccggg accaccctgc tggtgtccag ccacgtgatg gacgaggcgg cccgctgcga
     2461 ccggctgctg ctgatccgcc acggccggct gatcgccgac gacacccccg acgccgtccg
     2521 cgccgcgacc ggggtggacg acctggaaga ggcgttcctg cgcctcatcc gggccggcga
     2581 ggccggcccg gcggacatcg gggaggcggc gtgaacccga cgatcctggc cgccaccacc
     2641 gggcgcatcc tgcgtcaact gcggcacgac cggcgtacgg tggcgctgct ggtggtggtg
     2701 ccgacggtgc tgctcaccct ggtctactac atgtacgccg accagcccgc cccgcccggg
     2761 cgaccgtcgc ccttcgaccg ggtggccctg gtgatgctgg gcttcttccc gttcatcatc
     2821 atgttcctgg tgaccagcat cgcgatgctc cgggaacgca ccagcgggac gctggaacgg
     2881 ctgctcacca ccccgctggg caagctcgac ctgctcttcg gctacggcat cgcgttcggg
     2941 ctggccgggg tggtccagtc gaccgtcgcc gccgccgcgg cgtaccggct gctcgggctg
     3001 accaccgccg ggtccgccgc gctggtcgtg ctgatcgccg cggtcaacgc ggtgctggcc
     3061 gtcgcgctgg ggctgctgtg cagcgccttc gcccgcaccg agttccaggc ggtgcagttc
     3121 atgccggtcg tggtcgcccc gcaactgctg ctgtgcgggc tgttcgtgcc gcgcgaccag
     3181 atggccggct ggctccagac ggtcagcgac gcgctgcccc tgtcgtacgc ggtggaggcg
     3241 ctccaggagg tcggcgcgca ctccacaccg accggcctga tgtggcgcga cgtgtcgatc
     3301 gtggccggcg cggcggtggt ggccctggtg ctggcggcgg cgaccctgcg ccggcgcagc
     3361 gggtgagccc ggtgacccga cgcaccggcc gccgccccgg caaccaggac acccgggagg
     3421 cgatcctcac cgccgcccgg tcggcgttcg ccgaacgcgg tttcgacgcg gcctcgatcc
     3481 ggcaggtcgc caccgccgcc ggggtcgatc cggccctggt ccaccactac ttcggcagca
     3541 aggaggagct gttccgggcc accgtcgaca tcccggtcga cccggccgcg ctgctgcccg
     3601 ccgtgctggc cggcgacccg gacgggatcg gggaacggct ggtccgcacg ttcctcgggg
     3661 tgtgggactc gccggccggc ggggcggcgg tggcgctgct ccgctcggcg agcaacaacg
     3721 agtggacggc ccggctgatg cgcgagttcc tgaccaccca ggtgctgcgc cgggtgctcg
     3781 accagctcga cctcgacccg gcggaacggc cgctgcgcgg cgccctggtc gccacccaga
     3841 tgatcggcct ggccatgatg cgctacgtca tccgcctcga accggtcgcc tccgccaccc
     3901 ccgacaccct ggccgcaacc ctcggcccca ccatccaccg ctacctcacc gcccctctcc
     3961 cctaaccccg ccccggcgcc ccgccccggt gatgccccgc cccggtgatg ccccgccccg
     4021 gtgatcaaga ggtttatgtc acgaaagccg cccggcatga cgcaaacctc ttgatcaccg
     4081 gggcagcggg cgggggccgg ggggcggggg cagagggggg ggtcaggggt gggggtgggc
     4141 gggggtgggg aggtggagca gggggtgcag gaggtggggc aggtccgccg ggtcggtgac
     4201 cgggtggggg aacggcaggc gggtgcggcg gcggtcgccg ggtcggccgt acgccacgac
     4261 caggccgtag cggtccaggc gtaccacccg gggttcgtcg ccggtcagcc ggagccgacc
     4321 gcgcaggtac gcgaccgtct ccggcccgtg gtggttggcg agatcggcca gcagcgcggc
     4381 ctcgtcggcg tgcagcgggt ccggctcggc ggcggcgtac tcgccgggat cgacccggtg
     4441 caccacaccg gcggtctcca gccgggcctc gaccacctcg aagcggtgca gccggaagcg
     4501 gctccccacg tcgagcaggt cgccggtcgg gtccacggcg gcgaagtcga cggcggcgcg
     4561 acgggccgac tcgccgtcca gtggcaccgc ccagccggag acccaggccc ggccggccga
     4621 gggtgctccg gcggccggag gcagatcgag cacgtcgagc accacggcga cgtcccgggc
     4681 gacccccggg tccagctcgg cggccaggtc gctgaagacc gggacgagca gcagcacccg
     4741 cccttccacg tcggtggcgt gccggacgtg gaacggcccg gggcggtggg cgagatgcac
     4801 caggccgggc agccgaccgg ccaccagggt acggatcagc tcagcagggg tcggggccac
     4861 cgggcacctc cgataaaggt tagccttacc taacccgcag cgtagagcac ccgggcgacc
     4921 acgtccaccg accgccggtt ccgcagggac acgctgctca gcgacacgga cccggcggcc
     4981 ggtcgcccgt caccggcgcc gcgccggacg tcaacgggcc tggccaacca gccagccagc
     5041 cagccagcca gccagccgaa gcgtccacag caggtgggca gggcggtgtc tggtgccggc
     5101 cggtcagcgg gtctgttcca accaggaggc gtagagcagg ccgtagaccg agtcggggtc
     5161 acggagcagt tcctcgtgcg ggccgcgctg cacgatccga ccccggtcca ccaccaccac
     5221 ctcgtcggcg gcctgcgcgg tggagaggcg atgcgcgatg gccagcgtgg tacgaccccg
     5281 ggtcaccgcg tccagggtgc gttgcaggcg tacctcggtg gccgggtcga cggcgctcgt
     5341 cgcctcgtcc agcaccagca gatccggatc cgccacgtac gcccgggcca gcgccaccag
     5401 ctgccgctcc ccgacgctca acgcctcccc ccgctccccc accgcagtgg ccagacccgc
     5461 cggcagaccg tccaaccagt cggccagccc cagctcggtg aacgcggcgg tgagctgcgc
     5521 gtcggtcagc tcggggcggg cgaagcggac gttctccccg accgtggcgt cgaacaggaa
     5581 cccgtcctgc ggcaccatca ccacccggga ccgcaacgag tcgaaccgca cctcgtccag
     5641 cggcaccccg gacagcagca cccgcccctg cgtcgggtcc atcagccggg tgagcagctt
     5701 ggcgaaggtg gtcttgccgc tgccggtctc gccgaccacc gccacccggc tcttcgccgc
     5761 gatgtccagg gtgacgccgt gcagcaccgg cggcccgccc ggataggcga acgtcacccc
     5821 ggcgaagcgg atgtccaacg gcccggccgg cagctcccgg ccctgctcgc ccgggtcggc
     5881 cacgtccggc gcgatgtcga gcacgtcgag cacccgccgc cagccggcaa tggcgttctg
     5941 cgcctcgttg agcacctcgg tggcgatctg caccggctgg atgaagaggg tgaccaggaa
     6001 caggaaggcg gtgagctggc cgacggacag cgtccggtcc actccgagcg acaccccgac
     6061 caccaccacc ccggccagtg ccaccccggc cgccaactcc cccaccgagc tgcccatgat
     6121 gctgatccgg atcgcccgct gctgggccac ccgctgcccg tcgatcgcct cgtccagccg
     6181 gcgggccgtc cgcccggaca ccccgtacgc ccggatcacc ggcgcaccca ccacgctctc
     6241 ggcgatcgtg ccgagcaggg tgcccatccg ctgccggacc accccgtacg ccccggccaa
     6301 ccggcgctgc agcagccgga tcatcagcac cgccggggtg aacgcgacga gcaccaccag
     6361 cgtcaactgc caggagtacg cgagcatcac cgccgtggtg accgcgagct ggcccaggtt
     6421 gaccaggagg atgaccccgc cccactggag gaaatgggtg atctggtcga cgtcgctggt
     6481 cacccgggag accagcgaac cgcgccgctc ggactgctgg tgcagcatcg acaggtcgtg
     6541 cacgtgccgg aacgccctgg tccggacgtt ggccagcgcg gtctcgctga ccgtgaacag
     6601 ccgccgcatc atcaggtacc cgcaggcggt ggtgaccacc agcaccgccg tggtggcggt
     6661 gaccaccgtg acgatcaccc caaggtccgg accaccgggt acggcgatcc cctggtcgat
     6721 gccgcgttgc acggcgaccg ggaccgccac ccggccgacc atgtagacca acgccagggc
     6781 gatcgtgccg gccagtccgg tacgcagctc gggcgagagc gccagccccc ggcgcaacgt
     6841 ctgccaggtc ccctcgaccc gctcgtcccc gccacccaca ttcgcgctca ccggcgtcga
     6901 cccttcgttc gcgactgcgg ggctccgctg cgctgcactc ctcgcgctca ccgaaccaac
     6961 ccttcgttcg cgactgcggg gctccgctgc gctgcactcc tcgcgctcac cgaaccaacc
     7021 cttcgttcgc gactgcgggg ctccgctgcg ctgcactcct cgcgctcacc ggtccacctc
     7081 gatttccagg cccgacggca gcggggcgac ctcgtcgtac gtccggttct gttcgcgttc
     7141 ctgctcggcc tgctcgtagg cggtgaccag gtcgacgtag ccgggcacgc tggccagcag
     7201 ctcggtgtgg gtgccccggg ccagcacccg gccctgctcc aggtagatca cctcgtcggc
     7261 gagcgcgatg gtggcccgcc ggtaggccac caccaggatc gacgcggcgg ccggctggcc
     7321 gggtgccggg gcgcgcagcc cggccaggat ggccgcctcg acccgcgggt cgaccgcgct
     7381 ggtggcgtcg tcgagcacca gcagccgggg ccggccggcc agcgcgcggg ccagggtgag
     7441 gcgttgtcgt tggccgccgg agagcgaggt gccccgctcc ccgaccatgg tgtccagccc
     7501 gtcggggagg gcggcgacga aaccgtcggc ctcggccagc cgcagcgccg cccagacgtc
     7561 ctcgtcgtcg atgcccggcc ggtccaggct gatgttggcc cggacggtgt cgtcgaagac
     7621 gaacggcacc tgggcgacca gggcgacggt cgaggcgagt gacgcggcgg tgagccggcg
     7681 cacgtccacc ccgtcgaggg tgaccgtgcc ggcgtccggg tcgaccagtc ggaccgccag
     7741 cgaggcgatg gtggacttgc cggcgccggt cggcccgacc agcgccaccg tccgcccggc
     7801 gggcacggtg aaggcgacct cgccgagcac agacgtcccg ggcaggtgcg cctcggcggg
     7861 ctcgtagccg aagtggacgc cgtcgaaggc gagggtggcg ggcgtggcgt cgtcggcgag
     7921 ggtgccgtcc ccgtagggca tctcgccggt ggcgtcgagc acccggcgga cccggtccca
     7981 cccggccacg ctgcggggca gctcggccag cacccagccg atggcccgca ccgggaaggc
     8041 cagcacggtg aagaggaagg cgacgctgac cagttcggtg acggtgatcg caccctgccg
     8101 cagccggatc gtgccgacca cgagcacggc cagggtgccg aggctgggca gcgtctccag
     8161 cagcggatcg aagacccccc gcagccggcc gacggagatc agcgagtcgc gtagctcgtg
     8221 ggcccggccg gcgaaccggg cggtctcctg ggcctcccgg cccatggtct tgaccaccag
     8281 cgcgccgtcg aagctctcgt gggcgatccc gctgacctcg gcccgcagcc gttgcgcccg
     8341 ggcctggcgg ggggccatcc ggcgggagta gaccacgttg agcgcgaaca gggcggggaa
     8401 cacggccagc ccgaccaggg cgagcgccca gtcggtgacg aagagtgagc cgaccgcgcc
     8461 gaccagcatc accagcgtgc ccaccgcgaa cggcagcggc gcgatcggat accaggcggc
     8521 ctcgacgtcg gagttggcgt tggacagcaa cgtgccggtg gagttgcggt ggtgccagga
     8581 cagcggcagc tccaggtaac ggcgcgtcac ccggcggcgg taggcggcct ggaggcggaa
     8641 ctgcatgtaa ccggcgccga gccgacggcc gaagatgccc accacccgca gcacgctgat
     8701 cccgaacaac gccacggcgg ccagggccag cgtgctcgtg ccgacctcac cggactcgat
     8761 cgccggcacc accacgtcgc cgacgaccgc gccgaccacg tacgcgctga cgatcaccag
     8821 cccgccgaag agcacgctac cggcgaccgc caccgcgaag atccgcggtt gttcccggat
     8881 cgcccggccg aggacccaca acccccggtg gatcacgtcc cgactcgtcc cgctcgccac
     8941 gctctccccc gccgtaagcc gcaattatct cccttatcct taccgctcgc cgccacctac
     9001 gccgcccggc gcggtatgtc caccatcacg tcgcggaccg cgccaccaca ccgcacccgg
     9061 ggccgccggc ccgccgcacg gcgctgccgg accgcgcggg caggtgggaa gggtcgctcg
     9121 ccgcgccgac tgcggccgac cgtcctacga tcgctgcatg ccgcggtacg cccgagcgga
     9181 gcgcgaggcg ctcgccgacc tgatgctgga agtgggcccg gacgccccga cgatcaacga
     9241 ggggtggacc gcccgggacc tcgccgccca cctggtggtg cgggagcgcc gccccgacgc
     9301 cgccggtggc atcctgctgc cacctctgca cgggtacgcc gagcgggtgc ggctgcgcac
     9361 ggccgcccgg ccctggccgg agctggtcga ccaggtgcgc cggccgccgg tgtggagccc
     9421 ggtcagcaac ccgctcaccg acgagttggc caacacgatg gagttcttca tccaccacga
     9481 ggacgtccgg cgggcacggt cggggtggca cccccgggac ctcccggcgg ggctggccgc
     9541 ccggttgtgg aagccggtcg ctctgctcac ccggacccgg gcccgccggt tcccggccag
     9601 tctgctggtg caggcgcccg ggcacggcga ggtggccacc ggccggggtg gtgaccgggt
     9661 acgcctggtc ggctcccccg gtgagctggt gctgttcctc tcgggccggc aacgggtggc
     9721 ccgggtccag ctcgacggcc cgcccgcgtt gaccgagcgg ctgcgtaccg cccagctggg
     9781 gatgtaggcg ccccggcccg cacccgcgtg ccgtccgggc accggaccgc gcggtcggcg
     9841 agcacccgcg cgccagcagg tcacccgttg tgccgttccc gtcaccgctt gtcggggcgg
     9901 tcgattcgac cgccccgacc gtcaccggca atgatctgtg tcgattcccc aggcgtactc
     9961 tccggcaacg ccaccggtgg ggtggccgac tggggaaacc atgcgaagct tcgacgtctc
    10021 ggcgctgctc gaaccaccct tcgtcagccg acggcacccc gccaccgacg cggtggcggc
    10081 ggcgagcctg gagtgggccc accggcaggg cctggtcggg gcgggtcgtt cggcgggccg
    10141 gctgcaccgg gccggggccg ccgagctggc cggccgcgcc tgcccgcagg cgtcggtggc
    10201 gcacctgcgg ctgctcaccg acctgttctc ctggctgttc gtgatggacg acgtctgcga
    10261 cgacgacggg ctgggcagca cgccggccac cctcgcgccg accgtcgccg cactgctgga
    10321 cgtcctcgac cggcacgggg ccccgaccag ccggggcaca cccaccggcc ggtacgcacc
    10381 caccggccag ggcacaccga ccggccaggg cacaccgacc ggccaggacg caccgaccgg
    10441 ccggggcgct ccgggtgggg cgctcggtgc cgccctggcc gacctgtgcc gccgggttcg
    10501 cgaccagcgc cgccccgcgc tgctgctgcg gctggtcggc cagttgcggg cgtacctgct
    10561 cgcgctgctg tgggaggcgg cgaaccggga gcaccggcgg gtgccggggg tggcggagta
    10621 ccgccagatg cgccggcaca ccggtgccgt acgccccagc ctggccctca ccgatctggc
    10681 gtacggtcga ccgcccggtg cccggagacg ggtcgatccc gcgttggtcg cgttggacga
    10741 cctcgccgtc gacctggtct gctggtgcaa cgacctgttc tcctaccgca aggagcaggg
    10801 tccggtggcc gacccgcaca acctggtgac cgtcctcgcc gcgcagaccg ggcggggtga
    10861 ggcggacgcc ttccgcctgg ccgccgggtg gttcaacgac gggctggccg gctacctggt
    10921 ccgcgaggcg gcgttggtcg cgcacggcgg accggcgttg acgccctacc tggcggcccg
    10981 ccgctcgtgg ctgcgcgcca cctacgactg gtcggcacgg gcggaccggt acgcctgacc
    11041 cggccgccgc acccgcgggg cccgcgggag cggtcaccgg ccacccctgc agggattcag
    11101 ccgcctcaca ggtacggggg ctagccgatg ccccggcgca ggcaataccc ttcggtaacc
    11161 gcagcgcgac gtgacccccg tcacgtcacc cacccctgaa ggcggcttcc acgatggctc
    11221 tcgatatccc gtaccgctcc attcccgaca tgttccgtaa gcgggtggcc gcgacccccg
    11281 accagcacgc cttcgcccat ccggcacccg acgactccgg cccggtctgg ttgacctggg
    11341 cccaggtggg ccggcgggcc gacgcggtcg ctgcgggcct gcacgggctc ggggtcgggc
    11401 tggaggatcc ggtggcgatc ctggcgaaca cccgactgga gtggatcatc gccgatttcg
    11461 gcatcatgtg cgcgggcggg gcgaccacca ccgtctaccc caccaccgag ccgcaggacg
    11521 cggcgtacat catcgccgac tccggttccc gggtgctgtt cgcggagaac ccggcccagg
    11581 cggcgaaggt cgcgggcacg caactgcccg cgctgaccca cgtggtgctc ttcgacggca
    11641 cccccgaccc ggccgccgcc gtgccccagt tgaccctggc cgagctggag gagcagggcg
    11701 cgcaggcgct cgccgccgac ccgggcctgg tcgaccggct gatcgccccg gtcggccccg
    11761 atcacctggc gacgctgatc tacacctcgg gcaccaccgg ccggcccaag ggcgtcgagc
    11821 tgctgcacgg cggctggtgc tgggaggggg tggtgcaggc cgagacgggt ctgctgcgcg
    11881 acgacgacgt gcagtacctc tggctgccgc tgtcgcactc gttcggcaag acgctgctct
    11941 gcggctcgac acacgtcgga ctgccgacct acgtcgacgg gcgggtggac aagctggtcg
    12001 agttgctgtc ggtgatccgg ccgacgctga tgtgcggggc gccccgggtc tacgagaagg
    12061 tctacaacaa ggcggtcacc accgcgcagg acgccggcgg cgcgaaggcg aagatcttcg
    12121 cctgggccgt cgcggtcggc aaggagaaga tcgccctgga gcaggccggc cgaccggtgc
    12181 cgggtggcct gaagctcagg tacgcggtgg ccgagaagct ggtgttcagt aagctccagg
    12241 cccggctcgg cggccggatc cgggtgctcg tctccggggc ggccccgctg agcgcggaga
    12301 tcgccacctt cttcgccgcg gcgaacctgc ccatctccga ggggtacggc ctgaccgaga
    12361 ccagcgccgg caacttcgtc aacccgcccg acgggttgcg gatcggcacg gtcggccggg
    12421 cgatgggcga cctggagtgc cggatcgaca ccgacgggga gatcctggtc cggggccggc
    12481 cggtgatgcg cggctaccac aacctgcccg aggagacggc cgccgcgttc accgaggacg
    12541 gcttcttccg taccggcgac atcggcagcc tcgacgacga cggttacctg cgcatcaccg
    12601 accgcaagaa ggacctggtc aagacctccg gcggcaagta cgtcgcgccg tcgcacattg
    12661 agggcatgtt caaggcgatc tgcccgtaca cctcgcaggc gatcgtgatc ggtcaggccc
    12721 gcaactactg caccatgctg gtcagcctgg acccggatgc gatccggggt tgggcggcgg
    12781 gcggcccgct cgacgggcgc gactacgccg agatcgtcgc ctcgcccgag gcccgggcca
    12841 tggtcgagga gcacgtcgcc cagctcaaca ccaagctcaa ccgctgggag acgatcaaga
    12901 aggtgaccgt cctgccccgc gacctgacca tcgaggacgg tgagatgacc ccgtcgttga
    12961 agatcaaacg acgcggggtg gagagcaact tcgccgccga gatcgaccgg atgtacgcgg
    13021 gcagcctggc cgagatctga gcggtccggg ccggtcgacg tccgtgtccc cccgtcccgg
    13081 gacacggccg tcgaccggtc acaggtgctc gcgacgccac cggctctgct cggcctcggc
    13141 ggcttcctgt tccgccaggg ccaactggcg tacccggtgc cgacgccggc cctgcccccg
    13201 ggtctccacc accaccaggg cgacgcagac cagcgccagc agggccaacg cgcccacctc
    13261 ggacacccgg gcccccaccg gggcgagcgc ggccagcgcc agcaccgcca gcaccggcgg
    13321 ccagcgcagc acccgcagcg cccgcagccc gcaggcgacg aggctgagca ggtagagact
    13381 caccccgccg tagagcacca gcacccagta accacccagc ggcacccccc agtccgggtt
    13441 gtccgggtcg gccacctcgg tcagcaggtc cttgagcccg agggcgaaga agatgacccc
    13501 ggcgacgatc ggcaggtgca ggtaggtgta ggcgtcccgg gccaaccggg cccggtgtgc
    13561 cgggtcccgg ctgcggtgca gggcctgttc cagggcgagc gccagggtgt cgaagtaggc
    13621 ccaccagagc accgacgcca cggcgatgcc gagcaccgcg gcgatcacca ccggccaggt
    13681 cagcggcagg ccggtgacga acttcgggcc gacccccagc gcgatgatcg actcgccgag
    13741 cgcgatcagc accatcaggg cgtgccgttc cgcccagtgc ccggcggaga ccaccaccca
    13801 gtacgtcccg cccagccgca ccccggccgc gtactccagc agcagcgcgg ccgtccacag
    13861 ggtgagttgc agggcggtgg cggccccgtc cccggagatc cggttcggca gcagcgcgga
    13921 ggcgaccagc agggccgcgg cgaccaccgg cagcaccgcg agccgccgcc actgccgcca
    13981 ccgggccgcc tcgccccggg cgagcagccc gaagacggcc aactggcagg cccggaccag
    14041 gaggtagcag ccgacgaaga ccaacgggcc gttcagccca ccgggccggt cgttgaacgc
    14101 ccccggcatg ctcaacgcca gcaggaaggt ggcggcgatg gtgacgaagc cgaccaccgg
    14161 caacagcccc tggtcggcgc ggaccacgtt gccgacgccc gcgaacccgg tccagcacca
    14221 ccagagcagc cccagcacca gcaggcagcg cagcaggttg gtgccggtgg gctgctggga
    14281 ggtcagcgcg gtgacgttga agaaggcgaa gacgaagacc aggtcgtaga agagttccag
    14341 ccgggtggtc cgggagccgg gcgcaccgag ccggaccccg cgcgaccact gcgggctgcc
    14401 caccccggca gtctcccagc cgacgcccgc cgatcaggcc ggttcgtccc gaccgggacc
    14461 accgtcggtc cccggggcgg gccgtcaggc gatcactgcc ggttcccgcc agcgcgcccg
    14521 gccggcaccc cggtcgaggt cgtagcggat cgcggccagc cgcccgaccg cctccaccag
    14581 gtcggcggcg ggcagggtga agggcagtcg caggaagcgc tccagggtgc cgtccaggcc
    14641 gaaccgggga ccgggggcca gccgtacgcc gacctcctcg gctgcccggg ccagggcgct
    14701 ggagatcggg ccgtccagct ccacccagag cgtgacgccc ccccggggca ccccgacccg
    14761 ccagtccggc agccgctcgg ccagcacgtc gagcagggcg tcccgctggg tgacgagctg
    14821 cgcacggcgg gccgcgacga tcgccggtgc ctgggcgagc aggtgcaccg ccaccaactg
    14881 gtcgagcacc gggctggcca tgtccacccc gacccgggcg gcggccagcc gctgcacctg
    14941 cggcgcggag gcgcgtaccc agccgatccg cagaccgccc cagtagggct tgctcatccc
    15001 cccgatggag atcacccggg agtgccggtc gaagacggcg accggcgggg gcagcggtgt
    15061 gccgtccaac ggcaggtcca cgaaggactc gtcgacgacc aggtcggtgc cggcggcgtg
    15121 ggcggtggcg accagccgct cccgcagctc ggcgggcatc aggtggccgg tggggttctg
    15181 gaactcgggg atcaggtagg ccagtttggg ccgggtctgc cggacgctgc ccagcagcag
    15241 gtcggcgtcc cagccggcgt cgacggcgag gccgtgggtg ctgatccggg cccgccgggc
    15301 cgccaacgcg gcgagcgcgt tcgggtaggt gggcgattcg accagcacgt tcccgccggg
    15361 cgcgagggcc agccgcagca ccaggtccag cgcgtgctgg gtgccgctgg tcaccatgat
    15421 ctgctcggcg ctggtcggca acccccgctc ggtgtacgcc cgggcgaccg cctcgcgcag
    15481 ctcgatgatg ccggtcgggt ggtagcccgc gccggacagg taacgcggca ggtcctccag
    15541 ggcggctcgg gcggccggca ccagctcggg tggggcggcc aacgcggcca ccccgagatc
    15601 gatcatgtcg cggtcgtcca gcggggtcca caggccggtg ctggcgaccc ggtgggtgcc
    15661 gggcagcatg gtccagctcc ccgcgccgcg ccggctggcc aggtggccgg tctcccgcaa
    15721 ctgccggtac gcggcggtga ccgtggtacg gctgatccgc agcgcctcgg ccagctcccg
    15781 ctcggccggc aggcgtaccc ccagggggag ccggccgtcg gcgagcaggc cccggacggc
    15841 ggcggcgagc gcggcgtagt cggggctgcg gcgacggccc ggcagcgcgt gccactgtcc
    15901 gagcaaccgg gccaattgga cccctcgcac ctggctggtc acggccaccc cttcggaatt
    15961 ggctcttctg tgggtgatat tggactctag agtggcatgc atggctctga ttggcaatct
    16021 ccggcaccgc cccgcccggc ggctcaccca gctctatgcc gggctggtcc tctacggggt
    16081 cagcatggcc atgatgatcc gctccgggct cgggctggac ccgtgggacg tcttccacca
    16141 ggggctggcc cggcagaccg gcctgtcgtt cggcaccgtg accatcgccg tcggcgcggt
    16201 ggtgctgctg ctctggatcc cgctgcggca acggccgggc ctcggcacga tcagcaacgt
    16261 actggtgatc ggactggtgg tggacgccac ggtggccctg ctgccggccg ggtggccgct
    16321 gcccgcccgg atcggcctgc tgctcggcgg catcgtcgcc aacggcgccg ccaccggcct
    16381 ctacctcggc gcccggctcg gccccggccc ccgcgacggc ctgatgaccg ggtacgtcgc
    16441 ccgccggccg ggccgctccg tccggctggt ccgcaccgtc atcgagatca ccgtgctggc
    16501 cctgggctgg ctgctcggcg gcaccgtcgg cgtcggcacc gtcgcgtacg cgctgggcat
    16561 cggcccgttg gcccagttct tcatcccccg cttcgccgtc cccgccgaac cggtccaccc
    16621 ggaaccggtc cacccggaac cggaccccgg gccgcagatc cccgggccgc agatccccag
    16681 gccgcagctc tccggacggc aggtctccgg acggcaggtc tccgggccgc cgcctgcggt
    16741 gcccggccgc cgggctcatc cggagccggc cctcgggcca cccgtgtcgg cttccccgcc
    16801 gcccccgagc ctggcccccg ggtcaccggc caccgggtca ccggtgtccg ccgttccggc
    16861 gtccccggga gtccacccgg aggcaccggt ttccggcccc ggacaacggt tcccggcgaa
    16921 accgcctgcc gagggtccgg gggtgaccac gctgagctgc gctgacagaa caggggggaa
    16981 gtaggtgttt cctcagcgga cacctacagg catcattcgt gcatggggga gaatgcgtgg
    17041 cgctggacgg acgcctggat cttcgtgtca ctggtgatcg ccagcggcgc cggacggcac
    17101 cgccgcgcgg cggattcgcg ccgcccggaa ggggtccggc tcactgacgt gctgtccacc
    17161 gccgaccacc tcaaccaggc gatacccgaa cgacacgacg tggagacagc ggtccagcgg
    17221 ctggtcggcg cggggctggt caccgtctcc gacggctggt tccggatcac ccccgacggc
    17281 gagcaactct ggcgtacccg gccccgggcc ggagtgggcg gcaccgtcga cagcatgcag
    17341 ggggtgctca cccggcgaca cgccccgggc agcgcgcagt ggcacctgcc cgaggaggac
    17401 cacgccgccg ccgtgcagga gtacgtggtc cgctcgatcc cggccccccg ccgctccccg
    17461 gagggccaga ccggccgctg agccacccga cccgcaggga gcagccgcgc cgaccggtgc
    17521 gcggggcgac ccggcgacgg tgcgctcagc ggacagggtg cccggcgacg gtgcgctcag
    17581 cgctcggggt cggcggcgac ggtgcgctca gcggacaaag tgccccggcg ctgcgttcag
    17641 cggacggggt acccggcgga cagggtggcc ggcgcgctgc gttcagcgga cggggtgccc
    17701 ggcggtgcgc agggcgtcct tgacctcgcc gacggtcagc tcgccgaagt ggaagacgct
    17761 ggcggcgagc accgcgtcgg cccccgcgcc gatcgcgggc gggaagtgcg ccacccggcc
    17821 ggcgccgccg ctggcgatca ccggcacgtc gaccaccgcg cggaccgcct cgatcagggt
    17881 gaggtcgaag ccggccttgg tgccgtcggc gtccatcgag ttgagcagga tctcccccgc
    17941 gcccagctcg gccccgcgcg ccgcccactc gaccgcgtcg agcccggtgc cgcggcggcc
    18001 accgtgggtg gtcacctcga aaccgctggg ggtggtgccg gctggtgccc gccggacgtc
    18061 caacgagagc accagcacct gccggccgaa gcggtcggcg atctcggcga tcagctcggg
    18121 gcgggcgatg gcggcggtgt tcaccccgac cttgtcggcc ccggcgcgca gcagggtgtc
    18181 cacgtcggcg acctgccgga ccccaccgcc gacggtgagc gggatgaaga ccgactcggc
    18241 ggtccggcgc accacgtcga gcatggtgcc ccggtcgctc gaggacgcgg tgacgtccag
    18301 gaaggtcaac tcgtccgcac cggcccggtc gtacgccgcc gccagctcca ccgggtcacc
    18361 ggcgtcgcgc aggtcgagga agttgacccc cttgaccacc cgaccggcgt ccacgtccag
    18421 acacggaatc acccgtaccg ccaccgtcat gcgccgagcc tatccaacgc ccccgcccca
    18481 cccccctgcc ccgcccaccc aaccccacca accccgccac ctccccggtg atcaagaggt
    18541 ttacgtcagt tcgatctcca aaggtgacgc aaacctcttg atcaccgatg ccggggaggc
    18601 gggggaggcg ggcgggggcg gggaggggaa gggggaggga gggttagagg cggacgagca
    18661 ttttgccgag gttttcgccg cggaggaggc cgaggaacgc gtcgggggcg ttgtcgaggc
    18721 cgtcgacgat cgtctcgtcg taggagaggc ggccctcgcg cagccagccg gcgacctcgg
    18781 tgacgaactg ctcgcgcagg tcgccgtggt cgccgaccag gaagccgcgc agggtgagcc
    18841 gcttgccgat gaccagcgcc aggttgcggg gcgcggccgg cggctcggcc gagttgtact
    18901 gcgcgatcat gccgcagatc gcggcccgac cgtgcaggtt catcgccccg atggcggcct
    18961 ccaggtgctc gccgccgacg ttgtcgaagt agacgtcgac cccgtccgga gcggcggcct
    19021 tcagcgcgtc gcggaccgga ccgtcgtggt agtcgaaggc ggcgtcgaag ccgagctccg
    19081 tcaaccgggc caccttggcc ggcgagccgg cgctgccgac cacccggccg gcgccccgca
    19141 gcttggcgat ctggccgacc atgctgccca ccgcgccggc cgcgccggag acgaacacgg
    19201 tctcccccgg ccgcatcgcc gccacgtcca gcagcccggc gtacgcggtc agcccggtca
    19261 tcccgagcac gctcaggtag gcgctgaccg ggccgacgtc cggatcgacc cggcgggcgg
    19321 accggccgtc tagcagcgcg tactcccgcc agcccagccc gtgcagcacg gtgtcgccga
    19381 cgctgatccc gtcggccccg ccggccacca cctcgccgac cgccccaccg tcgaggggct
    19441 catccagggc gaacggcggc acgtaggact tgacgtcgtt catccggcca cgcatgtacg
    19501 ggtcgaccga catgaactgg ttacggacca cgatctgccc cgggcccggg gtgggcacct
    19561 cggtctcgac gaggcggaag ttgtcggccg tcggccaccc ctgggggcgg gaggccaggt
    19621 ggatctcacg gttgctggtc atccggtgtc gtcctctcgt acgcgatggt ggtggtctgc
    19681 tgcagcgctc aggccgcagc ggcctcgcgc acggtgagcg ccacctcgat gttgccccgg
    19741 gtggcgttcg agtaggggca gacctggtgg gcggcctcga ccagctgctg ggcggcggcg
    19801 cgctcgacgg ccggcaggtc caccaccagg gtgacggcaa gaccgaagcc gccgctgccg
    19861 ttcgctccga tgccgacctc ggcctcgacg accgagccgg tcacgtcggc cttggcccgg
    19921 cgggccacca cgcgcagcgc ggagtggaag caggccgcgt agccggcggc gaagagctgc
    19981 tcggggttgg ccgcgccacc tgcgccgccc atctccttcg gaatcgccag gtcgaggtcg
    20041 agggtggagt cggaggtccg gacgtggccg tcccggccgt cgccggtggc ggtcgcggac
    20101 gcggtgtaga gcacctgcat ggaaatcact gctccttctg tcggtggatc gtctcggtga
    20161 cccgggtgag ggtgtcgcgc aacgcgacca gctcggcctc gtcgagcccg gtggaacagg
    20221 ccacccgcaa cggcacgtcg gtcatccgtt ggcgcagggc cacgccgtcg gcggtcagcc
    20281 ccacctccac ccgtcgctcg tcgagcgcgg agcgggtgcg gaccaccaga cccgccgccg
    20341 ccagccgttt gagcagcggg gagagggtgc cggagtcgag ccgcagcgcg gtccccagct
    20401 cggagaccgt gggtggatcg tcgccgcgct cccacagcac cagcagcacc aggtactgcg
    20461 ggtaggtgag cccgaactcg tcgaggatgg gccggtagac gtcggtgagc gcgcgggagg
    20521 ccgcatagag cgcgaagcag acctgatcac gcaacaccag atggtcactc accgggaaaa
    20581 cgtagctcgc aattcaattg cgcacaactt atctggtcgg aagtgacccg ggtctccccc
    20641 gggcggcggg ccgggacgcc ccgggccagg acgccccgga ccaggacgcc ccggaccagg
    20701 acgcccggcg ggactcccgg atcaggagaa cacccgggtc aggacggcgg aaggtaggcc
    20761 tccagctcga cctccaccag atggtccgga tcgaccagcc cggcgacgac gacaagcgtc
    20821 gcagccggcc ggaccgggcc gaaaacggca ttgtgggccc ggccgacctc gtcgaggaag
    20881 agccggtcgg tcacgtacag ccgggtccgc accacgtcgg cggcccccgc acccacctcg
    20941 gccagggcag ccagggcgat ccgcagcgcc tgggcggtct gcgcggcggc atcgccgacg
    21001 tgcgtcacca ccccgtcgac ggtcgacgtg cagccggc
//
