LOCUS       NZ_JAFJXZ010000020     21455 bp    DNA     linear   CON 03-JUN-2024
DEFINITION  Paenibacillus polymyxa strain Hob6 Scaffold_20, whole genome shotgun
            sequence.
ACCESSION   NZ_JAFJXZ010000020
VERSION     NZ_JAFJXZ010000020.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 213575)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Draft genome sequence of Paenibacillus polymyxa strain Hob6,
            isolated from hemp (Cannabis sative) seeds' oil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 213575)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2021) Plant Science Departement, McGill
            University, 21111 Lakeshore, te-Anne-de-Bellevue, Quebec H9X 3V9,
            Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-JUL-2020
            Assembly Method                   :: SPAdes v. 3.12.0; Medusa v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly :: GCA_000507205.2; GCA_014706575.1;
            GCA_000164985.2; GCA_000597985.1; GCA_002893885.1
            Genome Coverage                   :: 266.29x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017589695.1-RS_2024_06_03
            Annotation Date                   :: 06/03/2024 02:57:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,275
            CDSs (total)                      :: 5,119
            Genes (coding)                    :: 5,024
            CDSs (with protein)               :: 5,024
            Genes (RNA)                       :: 156
            rRNAs                             :: 21, 9, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 19, 2 (5S, 16S)
            partial rRNAs                     :: 2, 7, 15 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 44 of 95
            Pseudo Genes (incomplete)         :: 63 of 95
            Pseudo Genes (internal stop)      :: 13 of 95
            Pseudo Genes (multiple problems)  :: 21 of 95
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 29755
            Orig. end                         :: 51210
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAFJXZ010000020.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21455
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21455
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21455
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11455](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11455)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(676..1737)
                     /locus_tag="JYU28_RS24220"
                     /old_locus_tag="JYU28_24260"
     CDS             complement(676..1737)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820230.1"
                     /locus_tag="JYU28_RS24220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24260"
                     /product="hypothetical protein"
                     /protein_id="WP_029516835.1"
                     /transl_table=11
                     /translation="MEETIYELMEQAQDMPGGAAKLAILEEAVRLADTSGLKELAYEIR
                     GEIVDCAIFNGYPLKSLIAFSWQLGQFDQNPEEYDADELLWNYKWILGKVCSFSNISKT
                     QIEDLAEDMRRRYAEYGYNERPYYYYKFRIAMDMGNLEEARRYLDTFRLIERDSMSDCE
                     ACEQSQMVRFYYLAGEDEQALAVAKPILSGRMRCAEVPHVTLSQVLLPLYRQGEVDQAK
                     EQHRKGYRLVRDDRDFLKTIAEHIEYLTIADPVQGIEVVERHLHMALDYESGLEQMYFY
                     ATMVSLLQKLDTSGEKRLIRLPASLEWGKEERTLTEIIAYFRPLAESAAADFDRRNGNT
                     FYSEWIGKIVQTA"
     gene            complement(1762..3657)
                     /locus_tag="JYU28_RS24225"
                     /old_locus_tag="JYU28_24265"
     CDS             complement(1762..3657)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820229.1"
                     /locus_tag="JYU28_RS24225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24265"
                     /product="HSP90 family protein"
                     /protein_id="WP_069010094.1"
                     /transl_table=11
                     /translation="MSQTDQYRFQVNLGGMIDILANHLYSSPRVFIREVLQNATDAITA
                     RKELRKVAAESKVLKEDKTLEATASESNNYEGKVIVELSGAGEQQVLMIQDNGIGLSEE
                     DIHRFLSIIGQSSKKGADLLASETSFIGRFGIGLLSCFMVSDEIVVLTRSVKEGVSMEW
                     RGKPDGTYTIRRLETELPVGTQIYLRCKPGSEFYYEPAHVEESLFYYGALLPYPVMLSV
                     DGETKRVNLPSTSWMQDPEQLRSRRSEVLDLGYRLMGERFSDFIPLRTASGRTGGIAFI
                     LPRSVNLNSKRLHRVYLKHMLVSDKAENVLPEWAFFIKSLIWTDELQPTASREYFYENE
                     QLDAVRSELGTCIREELLRMAEYEPDRLQHWIRLHELSMKALAVEDDEFLRIMHRWFSF
                     ESTFGRRELSELIREAGGRPLHYTSTVDEYRQITHVAAAQSMLVINGGYIYDSDILEKL
                     HWIDPNLQTERLSPEEVSLSFTGLTQEERENYYGVLRVMDAALQPMRCRAELKRFEPAS
                     LPVLYTISQDALTLRSMENTVEETTSLFSNVLDSLKAGVQQNSGYSTLYFNLNNPVVAR
                     ILEATDTQMVTAATEMMYVNALMMGHYPMNRSELGLMNRSVLHFINWGLGNGQNT"
     misc_feature    4004..4020
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.46"
                     /tool="antismash"
     gene            complement(4078..5592)
                     /locus_tag="JYU28_RS24230"
                     /old_locus_tag="JYU28_24270"
     CDS             complement(4078..5592)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019685877.1"
                     /locus_tag="JYU28_RS24230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24270"
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="WP_029516837.1"
                     /transl_table=11
                     /translation="MAAAVKAKMIVDKSFRIAEVDKRIYGSFVEHLGRAVYGGIYEPTH
                     STSDESGFRNDVKELVKQLDVPIIRYPGGNFVSGYNWEDGVGPVASRPRQLELAWRTVE
                     PNEVGTNEFFKWAKDVGSEVMMAVNLGTRGIDAARNLVEYCNHTGGSYWSDLRRSHGVE
                     QPHKIKTWCLGNEMDGPWQIGHKTAEEYGRLAVESAKAMKLIDPDIELVSCGSSSSTMP
                     TFPEWEATTLDHTYEVADYISLHQYYGNHDNDTANYLARSMDMDHFIHTVISTCDYIKA
                     KKRSKKKMMLSFDEWNVWYHSNDADKKIDPWSVAPPQLEDIYNFEDALLVGSMLITFLR
                     HADRVKMACLAQLVNVIAPIMTENSGKAWKQTIFYPYLHASRYGRGISLMPVVDSEKYD
                     SKDFTDIPYLDSAVVYDEEGDALTVFAVNRHLSESLELTVDVRSFEGYRIVEHTVLEHD
                     DLKATNSPAGEKVTPHNGGNAKLDDGIVKAHLGKASWNVIRLAKSH"
     misc_feature    5690..5710
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.48"
                     /tool="antismash"
     gene            complement(5901..7487)
                     /locus_tag="JYU28_RS24235"
                     /old_locus_tag="JYU28_24275"
     CDS             complement(5901..7487)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308385.1"
                     /locus_tag="JYU28_RS24235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24275"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_069010096.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.2e-13, bitscore:
                     43.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGKIHVAIIDDGVNAGFLNTQLLYNVEIAHGDVEDGRTLNHGTL
                     CAAIVQTYFPDAIISSVKIMNHRKGNATQLCAALDWCVKHGVQVANISLGSINYRDRSM
                     LREAVNDAAMAGLIIVCAAQNGGLLTYPASFANVIGVRCDHSGILTAGQYTYDAELAFS
                     SGIDFIAFAKHELVGAAGEAVQCPNSNSYATPLITAHICKVLQQSKAVPSIEQLKHMLH
                     KYSYLPIQDTKLPVMRYGHPDWIRRAYVFIEECAISSKAPYYFQTQCEAQPSGDKVAAI
                     IEQAILREREQQDTALEGGQRVCDLTDTIVLLGEMEPVSLQEVEQLASRYGKHVVYISK
                     NQRHTPSLNFSSCYLRWWQQEEGLFMAQEEASSIEDSRIPHICIYYDKGIDIIYFLHEL
                     RGAFARDEYQSWIAVDQSAAVLHDMEYTLPLDASNGLQELLYNAGKMAYNAYTDIAILC
                     VKAANTEDCTKERVLLGVDIELSLLVKVETEGIYISIRTEQGYLKEWVLSDLNAGDIGG
                     IYTYLEQLLVD"
     gene            complement(7636..8418)
                     /locus_tag="JYU28_RS24240"
                     /old_locus_tag="JYU28_24280"
     CDS             complement(7636..8418)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308384.1"
                     /locus_tag="JYU28_RS24240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24280"
                     /product="muscle M-line assembly protein unc-89
                     Uncoordinated protein 89"
                     /protein_id="WP_069010098.1"
                     /transl_table=11
                     /translation="MNVSFTSSHQSPFRTADNNRLELRHPFSAQAEKKGIGKPQNKVIQ
                     QLTEQKQNLMERRSDYLSNALKRGLGPEAVKAEMEEIDKQIQQIDENIQKQSLEEQKKA
                     LGMDEESKKEAQKGRKEEYTPKTAEEQQQRLVTYTMHSVVSANNELKSAKIAKTAQITL
                     GSEAKGWENANPAKSASLREKAEGLNGKIMEIAANINERISEAVNNEPMITDRVEPKEE
                     QEANPEAGRVWTEQELNAYLDSAKDGAKTAGTKVNIAV"
     misc_feature    8481..8493
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    8553..8567
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.52"
                     /tool="antismash"
     gene            complement(8576..8851)
                     /locus_tag="JYU28_RS24245"
                     /old_locus_tag="JYU28_24285"
     CDS             complement(8576..8851)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308383.1"
                     /locus_tag="JYU28_RS24245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24285"
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="WP_069010100.1"
                     /transl_table=11
                     /translation="MNFTQDVTGTGMTLENIFWKLFKIKAGEINKEATLLGPDMGLFPR
                     DLVYLLFEVEKSFAILIPEERIVGGGLLTYNSLYETIKGCLTVEKE"
     gene            complement(8865..9989)
                     /locus_tag="JYU28_RS24250"
                     /old_locus_tag="JYU28_24290"
     CDS             complement(8865..9989)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308382.1"
                     /locus_tag="JYU28_RS24250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24290"
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="WP_069010102.1"
                     /transl_table=11
                     /translation="MTNKLIIFPFDYETIALVRNLNLLGSYEEVVLISFQGSGMIGKDA
                     CVTDKGEVTGFIVKPESCLEQEMERCDAILLVKSNFKLDVAEVYLPVIKKAGQLGKKVM
                     CNFTLPDSCMEFIEPCEEHEDKLILKNTFDVRTKDILPPDPGSVIHDFFTPVLFVLGLN
                     ERTHKLNLQFNLRQKLEAQGYRVSQITSNGCGELIGAHSFPQFMFESGMTETQKIIMFN
                     RYLKKIEQSEKPDLILVGIPGGIVPFNNTFTNYFGVTSFLVSRAVRPDGLICCLHYDEY
                     NIKYLEHVKQYMENRFSSSLLGYAICNNVFDSYSSSTVNMQYASVDHRFVEEKKQEFSN
                     YSVPVLHLSNDEDMNRLTENILHYFSVDHHVVQL"
     gene            complement(10001..11455)
                     /gene="ccpM"
                     /locus_tag="JYU28_RS24255"
                     /old_locus_tag="JYU28_24295"
     CDS             complement(10001..11455)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="ccpM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308381.1"
                     /locus_tag="JYU28_RS24255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24295"
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="WP_245231681.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     5.8e-14, bitscore: 45.8, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 4.3e-55, bitscore:
                     180.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.7e-14, bitscore: 47.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.2e-11, bitscore: 38.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMCQPFIYTFQTRLHHYVYDVNTNLILRIKEEAYHFLNSHSSFN
                     LDQMEATPELQQYIRDLLDNGFLSSQRPQIMNHPKTKHLEHMLQHQLKTLTLQVTQNCN
                     LRCSYCVYSGGYDNRGHTNLMMDFETARKCIDFVIDRSVDSDRLDFGFYGGEPLINFPL
                     VKKCVEYIKEQVAYRDVGFHLTTNGTLLNDDILDFLDEHRFVLTISLDGDQENHDRNRR
                     FAVNGRGSFDTIIANVDKIKRNYPDLFEWINFNVVLDTRNDFGCINDFYTNYETFESLY
                     SVRSSYINDAYVKDEILYRNEFIEQRGYEVVKMMLSKFGRVDESHVSKLIKDYYIQIYF
                     RMFHYRKPSAGMPIEAHHGGPCVPGVQRLFADVHGNLYPCERVSEQSEVVQIGTVDTGF
                     EVDKINRILNVGTITEDACKNCWNFRFCTLCVAVADDLHTLSKEKKLSHCSVVKNDIRH
                     TLLDYCMMNELGYDFSEDTILDFEKA"
     aSDomain        complement(11084..11455)
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JYU28_RS24255_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="9.10E-15"
                     /identifier="RREFam021.1"
                     /label="JYU28_RS24255"
                     /locus_tag="JYU28_RS24255"
                     /protein_end="124"
                     /protein_start="0"
                     /score="45.8"
                     /tool="antismash"
                     /translation="MNMCQPFIYTFQTRLHHYVYDVNTNLILRIKEEAYHFLNSHSSFN
                     LDQMEATPELQQYIRDLLDNGFLSSQRPQIMNHPKTKHLEHMLQHQLKTLTLQVTQNCN
                     LRCSYCVYSGGYDNRGHTNL"
     gene            complement(11527..11712)
                     /locus_tag="JYU28_RS24260"
                     /old_locus_tag="JYU28_24300"
     CDS             complement(11527..11712)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04065.1"
                     /locus_tag="JYU28_RS24260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24300"
                     /product="CLI_3235 family bacteriocin precursor"
                     /protein_id="WP_080710748.1"
                     /transl_table=11
                     /translation="MRKLVKRSANVGDTIEAFGCGCSCYCPCSCYCAGSLTRSSNTSRE
                     SDGSYRRDNGTGIGNY"
     gene            complement(11817..13559)
                     /locus_tag="JYU28_RS24265"
                     /old_locus_tag="JYU28_24305"
     CDS             complement(11817..13559)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308379.1"
                     /locus_tag="JYU28_RS24265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24305"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_069010104.1"
                     /transl_table=11
                     /translation="MKESIVYKRLVATFRPYLKTVTIILICLILSAGLNILLPLTSKVI
                     VDQGLLKGNMQAVILYTSAAFLIVCLDKLLNVCKETFRAGLSAQVTFSLFEKAYLHLTR
                     VRMSYFNRTNEAELLNQIGTDVGNVSRITDSGVFFVIMQAFSMIGGLCGLLLINWKMTV
                     IVLLFLPIKYVVVKYFVKRRKKLVGDFIEGSSDFAQWFGESVGGMKEQRMFGLIPHKHQ
                     QFSTKQRRIVDSERKLSLLDAWNIASESILIQLLMMLVYVVGANLIFRLQLTVGGIFAF
                     VSYSAYVTTPVFAILNIGYMLAEVVPSAIRYYQFLDWAEEETSNSVTPASILTEPPFED
                     HIAFHHVSFSYTKDEPVLSDVNFRIARGEKVAIIGANGAGKSTLLDLMMRFSQPDQGII
                     TYDGIDIQSYEIDEYRSQIALVSQQVYLFDTTIFGNIRIGTEVTNDAIEAIIAEIGLEE
                     LVQNSADDFLIGSNGSRLSGGQRQKIAMARALIREASLFILDEVTSNLDTEARLNVQRL
                     LKTRLRDKTVIIVTHRSEILAHVDRVILLENGEPAQIGSHSHFMTCHAEYRGWVLEKEE
                     VPIK"
     misc_feature    13743..13752
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            13789..14364
                     /locus_tag="JYU28_RS24270"
                     /old_locus_tag="JYU28_24310"
     CDS             13789..14364
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016430.4"
                     /locus_tag="JYU28_RS24270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24310"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_277884425.1"
                     /transl_table=11
                     /translation="MVIDCCKEDQCRGSSRCFYRKICELYLSEVYRFCMHLVKNQSCFT
                     FMAEECTQDTFVAARQQLVKLKQHPNVKGWLYLTAKNLIYKSFRCYYTQKKHETTLECE
                     KICSYSNSVEEEWENRRLGDVDTVIVNILMQLSNNEYTLYEDYFCRQLAVPFLAVKYNI
                     SVTATTTRIYRLKRKLRTLSHQYCLTHI"
     gene            complement(14459..15313)
                     /locus_tag="JYU28_RS24275"
                     /old_locus_tag="JYU28_24315"
     CDS             complement(14459..15313)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308375.1"
                     /locus_tag="JYU28_RS24275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24315"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_069010182.1"
                     /transl_table=11
                     /translation="MKTAVQQARANTRSGEKTFQWFVATLLTVGGLLMVLPFAWMILSS
                     FKTEGEVTQIPPTIWPQHFTLDNFKLLFDSMAFGTYLTNTLIIVLASFFGLFLNAMAGY
                     GFAKFQFKGKGFLFYLVLATMMIPGQVTMIPVYLILNQMGLTNSMLGIVLPGLVGAFAI
                     FLFRQFMSDIPEELLEATRLDGAGEFRTFLQIVLPISTPIIAVQAILTFIGGWNSFLWP
                     LIIANDEKLYTLSVGLSLLKGQNESQFALQMAGSTFMVVPIMIIFIVFQKYIIENYTIS
                     GIK"
     gene            complement(15332..16216)
                     /locus_tag="JYU28_RS24280"
                     /old_locus_tag="JYU28_24320"
     CDS             complement(15332..16216)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014279338.1"
                     /locus_tag="JYU28_RS24280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24320"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_013308374.1"
                     /transl_table=11
                     /translation="MKGSSQKLAPYLFIGPSIILLTLFSLLPILLALVISFTDMDLSGL
                     VNYDSIRFIGLENYTNVLLDPSFIKSLGNTLFFVIIGVPLVLIFSLSIAILINMGKSRA
                     FKVFRVVFYLPSVTNVVAVAVVWSYLYNPTLGLFNYVLGLMNLGPVPWLTDPTVAKVSL
                     IVLAVWRGIGLNMIIFIAAIKGIPGSYYEAAQLDGANTWQQIRYITLPQLRYAIFFVSI
                     TTMIGWLQFFEEPFVMTKGKPLDGTLTASLFIYNNGFQFSKFGYAAAGSFILFFAIIAV
                     TLIQFRLQNKAES"
     gene            complement(16253..17506)
                     /locus_tag="JYU28_RS24285"
                     /old_locus_tag="JYU28_24325"
     CDS             complement(16253..17506)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017425689.1"
                     /locus_tag="JYU28_RS24285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24325"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_029516846.1"
                     /transl_table=11
                     /translation="MMKRTLGIILASTLLLGGALVGCSSKDDSSGKDASGKTTITLWGM
                     GAEGKLLPEIVKGFEKENPDIHVEVQALPWDNAHDKLLTAVASKSGPDVVQLGTSWVPE
                     LASAGALTDITPYISKYPELESKNFFEGAVGTTKFEGKPVGVPWYTETRVLFYRSDLLK
                     QVGYNEAPKTWEELSDAAQKLAARGKGKYGISFSAKEQSMGFMFALQNGSKLVDEQGNP
                     LFNQPPFVDAVKYVNTFFQNGSNAVDIGIDSVQGLQGEGIVPMFISGPFMIKEIKSKAP
                     ELEGKWNIAELPGKVNNLSVLGGANLSIMKFSKHPEESAKFLAYMSKPETQLKWMDLSS
                     NLPATTKSWEDAKLKSDPMLRTIRKQLDHSAALPQLAAWEEVSQQFIKSFERIYRGHAD
                     VQKEMDDFNQQAASIMKK"
     misc_feature    17644..17656
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            18108..20270
                     /locus_tag="JYU28_RS24290"
                     /old_locus_tag="JYU28_24330"
     CDS             18108..20270
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308372.1"
                     /locus_tag="JYU28_RS24290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_24330"
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="WP_081317505.1"
                     /transl_table=11
                     /translation="MEQHLNSYLESMTLEEKVDQLLQLVGAFFEEAGTDSQITGPMASL
                     GITEKNVHNVGSVLGIAGAKEAIRVQQAHLSKNRLGIPLLIMADIVHGFKTIFPIPLAI
                     GCSWDMRLAEESATIAAREAAVSGVHVTFAPMVDLVRDPRWGRVMESTGEDPHLNSQFA
                     RAFVRGFQGKDLTNDTDRVAACVKHFAAYGAGEGGRDYNTVDVSAWQLREYYLPSYKAA
                     LDEGCEMVMTSFNTVEGVAATGNKRLMRDLLRDEWGFDGVLISDWAAIKELIPHGIAED
                     EREAAKKALLAGVDIEMMTSCYNGHLPELVRSGQLDEALIDEAVMRILKLKQKLGLFEN
                     PLRGADPEREREVVFCEAHRTVAKELAIKSCVLLKNDSVLPLNRNQHIALIGPFAESGD
                     ILGSWSWSGSQEEAIRVVDGFQSKISSSLLTVATGCSIDDITEEQYAEALQVASQAEVI
                     VLALGERSDMSGEAGSRSNIRLPQAQLELVKRLKTLNKPMVAVLFNGRPLDLHGVIEEA
                     DAVLEAWFPGGEGGAAIADLLYGDAEPTGRLTMSFPQSVGQVPVYYNHFNTGRPQLDPN
                     TKERYVSQYLDVPNEPLFPFGYGLSYTDVAYDSVQLSGDTLIPGQELTVKVQVTNTGTR
                     PVEETVQFYVRDISGDTVRPMKELKDFCKVLLAPGESREVEFALTEPQLRYHHADLSFS
                     SDSGEFAVFTGPNSRDTSESRFRLVK"
     misc_feature    complement(20729..20744)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.42"
                     /tool="antismash"
     misc_feature    complement(21076..21088)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.49"
                     /tool="antismash"
ORIGIN
        1 tgtaaccact tgtttgtagg catgaagtgc ggtaaccccg aattgggtgg catactcgga
       61 tgggcggacc ataatttcga tatacagcgc ccccgtcttg atttcaggag caagctgcgc
      121 acagagcgcc agcgattcgt gattaaagct ggatatgatt acctgctgtt ctaatccaaa
      181 acgcttcacg gcagcaatga cctcttcctc catacccgga tagagataaa tgctgttttt
      241 caactctaaa ttaataattg tattcgagga ggattgggct agttccagta gctcatccag
      301 catcgggacc cgctcacctc gaaatttctc accaaaccag ccgcccgcat ccaatttatt
      361 taattcttcc agcgtaatat cccttacatc cagtgagcaa cctgtcgtac gctccagcga
      421 ctcatcgtga atcagcacca gatgcccatc ttgggtacgc tgcacatccg tctctatacc
      481 tgttgctccc agttccaagg cgtggcggaa tgccgccatc gtattttcag gacatacacc
      541 tgaagctccg cggtgcgcga aattaatcac cttttcggtt acagtcacaa cataacccct
      601 cctgtcattt cacaggaaca ttatacctgc tcattgtttg ggcagtataa aatattcgtc
      661 acagctacac ttcttctatg ccgtttgaac aattttcccg atccactcgg aataaaacgt
      721 attcccgttc cgtcgatcaa aatcagccgc cgccgactct gccagtggcc taaaatacgc
      781 aatgatttcc gtcaatgtgc gctcctcttt cccccattcc aaggaagccg gcaaccggat
      841 caaccgtttt tctcccgaag tatccaactt ttgcagcaga ctcaccatcg tcgcgtaaaa
      901 atacatctgc tccagcccgc tctcatagtc tagcgccata tgtagatgac gctctaccac
      961 ttcgatccct tgaaccggat cagcaatcgt caaatattcg atatgctctg ctatcgtttt
     1021 cagaaagtca cggtcatccc ggactaggcg atagccttta cgatgctgct cctttgcctg
     1081 atcaacctcg ccttgacgat aaagcggcaa tagcacctgc gagagcgtca catgcggcac
     1141 ttctgcacat ctcatacgac ccgacaaaat cggttttgcc acggcaagcg cctgctcatc
     1201 ctctccggcc aagtagtaga accgcaccat ttggctctgc tcgcaggctt cacaatcact
     1261 catactgtcc cgttcgatca agcggaaggt atccagatat cgccgtgctt cttccagatt
     1321 tcccatgtcc atcgcgatgc ggaacttata atagtaatat ggacgctcat tatacccgta
     1381 ttcggcataa cgtctgcgca tatcctccgc cagatcttct atttgagtct tcgatatatt
     1441 ggaaaagctg cacaccttcc caagtatcca tttgtaattc cacaacagct catctgcgtc
     1501 gtattcctct ggattttgat caaattggcc caactgccac gaaaaagcaa tcagcgactt
     1561 caatggatat ccgttaaaaa tagcgcagtc tacaatctct ccccgaattt cataagcgag
     1621 ttccttcaat ccggaagtgt ctgccaagcg aacagcctct tccagaatcg ccagctttgc
     1681 cgcccctccg ggcatatcct gcgcctgctc catcaattca tatattgtct cttccatttg
     1741 aatcctccct taattacgca attacgtatt ctgtccgttc cctaatcccc aattgataaa
     1801 atgcagtaca ctgcgattca tcagtcccaa ttcactgcgg ttcatcgggt agtgccccat
     1861 cataagcgca ttcacataca tcatttctgt agcagccgta accatctgcg tatcggtagc
     1921 ttcaagaatt cgggccacca ccgggttgtt cagattaaag tataaagtgg agtagcccga
     1981 attttgctgg actcctgctt tcagactatc aagcacattg gaaaaaagtg aggttgtctc
     2041 ctcaaccgtg ttttccatgg agcgcaaggt cagtgcatcc tgagaaatgg tatacaatac
     2101 tggcaaactc gcaggctcaa aacgcttcaa ctcagcgcga caacgcattg gctgcaaagc
     2161 agcatccatg acacgtagta caccgtaata attctcgcgc tcttcctgtg ttagcccggt
     2221 aaatgataga gatacttcct cagggctaag acgctctgtt tgcaggttag ggtcaatcca
     2281 atgcagcttt tccaaaatgt ctgaatcata aatatagccg ccattgatca ccaacatgga
     2341 ttgcgccgcc gccacatgcg taatctgacg atactcatct actgtcgatg tgtaatgcaa
     2401 cggacgtccg cccgcctctc ggatcagttc actcagttca cgccgcccaa atgtactttc
     2461 gaaggaaaac cagcgatgca taatccgcag aaattcatca tcctcgaccg cgagcgcctt
     2521 catggacagc tcgtgcaaac gaatccagtg ttgcaaacgg tctggttcat attccgccat
     2581 gcgtagcagt tcttcccgaa tacaggtccc caattcagaa cgaaccgcat caagctgctc
     2641 attttcataa aaatattcac gtgatgccgt tggttgcaat tcatctgtcc aaatcaggct
     2701 tttaatgaag aatgcccatt ctggcaatac attttccgcc ttatcggaca ccaacatatg
     2761 cttcaagtac acccggtgca gccgcttgct gttcagatta acactacgag gcaaaatgaa
     2821 tgcaatcccg cctgttctgc ccgatgccgt ccgcaacggt ataaaatcac tgaagcgctc
     2881 gcccatcagg cgatagccta aatctagcac ctcactacgg cggctccgta attgttctgg
     2941 gtcctgcatc cagctcgtcg atggaagatt gacgcgcttg gtctccccgt ctacagacag
     3001 catgaccgga tacggcagca acgcaccata atagaataaa gactcctcta catgcgccgg
     3061 ctcataataa aactcacttc ccggcttgca gcgcaaataa atttgcgttc ctacaggcag
     3121 ttcggtctcc aatcgacgaa tcgtatacgt cccatccggc ttccctctcc attccatgga
     3181 gacgccttcc ttcaccgagc gggtcagcac cacaatttca tcgctcacca taaagcagga
     3241 tagcaaccca atcccaaatc gtccgataaa cgaagtctca gaagccagca aatcggctcc
     3301 cttcttggaa gactgaccga taatcgataa aaaacggtga atgtcttctt ctgacaaccc
     3361 aatgccgtta tcctgaatca tcaatacctg ttgctccccg gcaccagata actctacgat
     3421 gactttgcct tcatagttgt tactctcaga agctgtagct tcaagggtct tgtcttcttt
     3481 caatacttta ctttcagcag caaccttccg cagctccttg cgagccgtga tcgcatctgt
     3541 tgcattttgc agaacctcac gtataaacac tcgtggactg ctatataaat gattggccaa
     3601 aatatcaatc ataccgccca agttcacttg aaaacgatat tggtctgttt gactcataga
     3661 gatcattcct ttctcgaaat gctactgcca tcatctggtt taaatagact gtcttttaaa
     3721 gtataacgtg gatttaagtc ggattgcaca ccctgcattt caggtatcag tacgttgata
     3781 acgatataac agggcctttt ttcacccggg aagtctggca ctgggtctaa ttaacttcac
     3841 aaaaatgtac ggagtacgat cacttagtga ataaggatca tctttgtcta gttaaattta
     3901 gtaataaaca taatatttat ttaaaatcca cccttctctc agaaccctat atctatggag
     3961 ggacaaatgg ctcattttac gcaaaaagct cgcattgccg ctcttgtagt actcttacaa
     4021 gagagaatgc gagcttattt aggtacagtc gaagctgtac ccttttacag aagagaatta
     4081 atgagactta gcgagacgga taacgttcca cgatgctttg cccaaatgag cttttacaat
     4141 tccgtcatca agcttggcgt taccgccgtt gtgaggcgta actttttcac cggctggact
     4201 gttggtcgct ttaagatcat catgctccaa tacagtatgc tcgacaatgc ggtagccttc
     4261 aaaactgcgt acatctactg tcagctccag cgattcagac aaatgacggt tcactgcaaa
     4321 gacagtcagc gcgtctccct cttcatcata aactacagcg ctgtccagat aagggatgtc
     4381 tgtgaagtcc ttggagtcgt atttttccga atccacgaca ggcatcagcg atatcccacg
     4441 accataacgg gaggcatgca gatacggata gaagatcgtt tgtttccacg cctttccact
     4501 attctcggtc atgattggcg caataacgtt gaccagttgg gcgagacaag ccattttcac
     4561 acgatccgcg tggcgcagga acgtaatcaa catgctgcct accaacaatg catcctcaaa
     4621 gttatagata tcctcaagct gcggtggtgc cacagaccac ggatcaattt ttttgtccgc
     4681 atcattggag tggtaccata cgttccattc gtcaaagctg agcatcattt ttttcttgct
     4741 gcgtttcttt gctttgatat agtcacaagt cgaaatgacc gtatggataa aatgatccat
     4801 atccatagag cgtgccagat aattagccgt atcattgtca tgattgccgt agtattggtg
     4861 caaggaaata tagtcggcta cctcataggt atgatccagt gtggttgctt cccattccgg
     4921 gaacgttggc atcgtggaac tggagcttcc acaggataca agctcaatgt caggatcaat
     4981 cagcttcata gcttttgcag attcaacagc cagacggcca tattcctctg ctgtcttgtg
     5041 accaatctgc catgggccat ccatctcgtt accaagacac caggttttaa tcttatgtgg
     5101 ttgctcaacc ccgtgactac gacgtagatc actccaatag gagccgcctg tgtggttgca
     5161 atattcgacc agattacgcg cagcatcaat tccgcgtgta cccagattaa ccgccatcat
     5221 gacttcggaa cctacatcct tggcccattt gaaaaattca ttcgtgccta cttcatttgg
     5281 ctcgaccgtt ctccacgcca gctccaactg tctaggtctg gacgcgacag ggccgacacc
     5341 gtcctcccaa ttgtaaccgg atacaaagtt accgcccgga tagcgtataa taggaacatc
     5401 aagctgtttt accaactctt taacatcatt acggaaaccg ctttcatcac tagttgaatg
     5461 agtaggctcg taaataccgc catatacggc acgcccgaga tgctctacaa aagagccata
     5521 aatgcgttta tcgacttcag caatacgaaa agatttgtct acaatcatct ttgcttttac
     5581 agctgctgcc acctaaacca tcctctctga atgcgaaaat aaaatccttt ctaccaccaa
     5641 gattaagaag ccgttttatt tacggtttta atataacaca ccctatttat tatagtcaat
     5701 attatcatta aatacttaat atattcatta acatttataa taaacgataa gcaattggtt
     5761 acgtatttct aaatattttg ttttataaac aaacttattg agtgaataac cactttgcca
     5821 aataataata ataacggatt ataggtgcgt tcaaaatagt gctactgccg tatcttgcag
     5881 tctgttttaa atagtgaata tcagtctacc aacagttgtt ctaaatatgt ataaatacca
     5941 cctatatcgc ccgcgtttaa gtctgagagg acccattctt tcaaatatcc ctgctctgtc
     6001 cgtatagata tgtaaatacc ttcagtttcc actttcacca gcaaagaaag ctcaatatct
     6061 acgcctaata aaactcgttc tttggtgcaa tcctcagtat tcgcagcctt tacacacaaa
     6121 atagcaatat ccgtataagc gttatatgcc attttacccg cattatataa cagttcctgt
     6181 aatccattgc ttgcatccaa agggagcgta tactccatat catgcaacac tgccgcggac
     6241 tggtccaccg cgatccagct ttggtattca tcccgggcaa aggcccctct caactcatgc
     6301 aaaaaataaa taatgtcaat gcccttatca taataaatac aaatatgcgg aatgcgtgaa
     6361 tcctctattg agctagcctc ctcctgcgcc ataaagagcc cctcctcttg ctgccaccag
     6421 cgcaaatagc aagatgaaaa attcagtgat ggggtgtgtc gttgattttt agagatatag
     6481 acgacatgtt ttccataccg tgaagccaat tgttccactt cctgcaagct cactggctcc
     6541 atttccccta gcaagacaat cgtatctgtc aggtcgcata cccgttgtcc accttcgagc
     6601 gctgtatcct gttgttctcg ctcccgcagg atggcttgtt cgatgatcgc ggcaactttg
     6661 tcgccagagg gttgagcttc acattgggtc tgaaaataat agggtgcttt cgaactaatt
     6721 gcacactcct ctataaacac ataggcgcgc cgtatccaat ccggatgtcc gtaacgcatt
     6781 acgggtaatt tagtatcctg tatcggaaga tagctatact tatgtaacat atgttttagc
     6841 tgttctatgg aaggaacagc tttggactgc tgcaaaactt tacatatgtg tgctgtaatc
     6901 aatggagtgg catagctatt gctgttggga cattgtacag cctctccagc tgcacctact
     6961 agttcatgct tggcaaaagc gataaaatcg ataccgcttg agaatgctaa ctcagcatca
     7021 tatgtatatt gtcctgctgt gagaataccg ctatgatcgc agcgcacacc aatcacattg
     7081 gcaaaggagg ccggataagt aagaagtcct ccgttttgtg cagcacatac tataattaat
     7141 cccgccatag ctgcatcatt tacagcctcc cgcagcatgc ttcgatctcg ataatttata
     7201 ctccccaggc tgatatttgc tacctgtaca ccatgtttta cacaccaatc cagcgcagca
     7261 caaagctgag ttgcatttcc ttttctatgg ttcattattt ttacactgct aatgatcgca
     7321 tctggaaaat acgtttgtac aatagctgca catagcgtac cgtgatttaa ggtacgtcca
     7381 tcttctacgt ctccatgagc tatttcgacg ttatataata attgggtgtt taaaaagcca
     7441 gcattaaccc cgtcgtcaat aatggctaca tgaatcttgc cattcatgtt ttctccccct
     7501 gtctcttcgg attgtggaat gaatctcacg gctctgttcc gttctattag agtaagcgga
     7561 gggtgcctct gcgaacgata gcgttcgtct gaaagcaccc tcctaattta gcaaaccatg
     7621 tacataatag ctggatcaga ctgcaatatt caccttcgtg cctgcagtct tcgccccgtc
     7681 tttggccgag tccagataag cattgagctc ttgttcagtc cacaccctgc ctgcctctgg
     7741 atttgcctcc tgctcttcct taggttcaac ccgatctgta atcatcggtt cgttattcac
     7801 tgcttcactg atacgctcat taatattcgc agcgatttcc atgatctttc cattaagtcc
     7861 ttctgccttt tcacgcaaag acgctgattt tgcagggtta gcgttttccc accccttagc
     7921 ctcgcttccc aatgtgattt gtgccgtttt ggctattttg gcactcttca actcattgtt
     7981 tgcagataca acactatgca ttgtataggt gaccaatctt tgctgctgct cctcagcagt
     8041 cttaggcgta tattcttcct ttctaccttt ttgagcttct tttttactct cctcatccat
     8101 gcctaaagcc tttttttgct cttccagtga ctgcttttga atgttctcgt caatttgctg
     8161 aatctgttta tctatctctt ccatttcagc ttttacagct tctggaccga gaccacgctt
     8221 gagcgcatta cttaaatagt ccgaacgcct ctccatcaaa ttttgctttt gttctgtcaa
     8281 ttgttgaata accttgtttt gtggcttgcc tatacccttc ttttcagcct gagcggaaaa
     8341 gggatgccgt agttcaagtc ggttgttatc tgcggtgcgg aacggcgatt ggtgagatga
     8401 tgtaaatgat acattcatcc taaaacctcc aattctcttc taaatgagga ttttttcaaa
     8461 aatcgagtaa gcgactgaaa tcgaattttg caaaatcctg aaataagtga ttctagaggt
     8521 atatcggata tttttgtatg tttttgtatg ttttatcatc attttcacaa atccttcatt
     8581 ccttttccac tgttaagcag ccctttatcg tctcatacaa gctgttatat gtaagcaacc
     8641 cccctcccac tatacgctct tccggaatta ggatagcaaa acttttttcc acttcaaata
     8701 atagatatac cagatccctg gggaacaacc ccatatcagg ccccagtaat gtagcctctt
     8761 tattgatctc gcccgctttt attttaaaaa gcttccaaaa tatattttcc agtgtcattc
     8821 ctgttcccgt tacatcctga gtaaagttca tgttcttccc tccattacaa ctgaactaca
     8881 tgatgatcaa ccgaaaaata atgtaaaata ttctccgtca gcctattcat atcttcatcg
     8941 ttggacagat ggagtacggg cacggaataa ttggaaaatt cctgtttttt ctcttccacg
     9001 aaacgatgat caacagatgc atattgcata ttgaccgtgg aagaagagta actgtcgaat
     9061 acattgttac atatggcgta tcccaataag gaagaggaaa agcggttttc catgtactgt
     9121 ttcacatgct ccaaatattt tatattgtat tcatcatagt gaagacaaca gatcagtcca
     9181 tccggtctga cagcacggga taccaaaaaa gaggttactc caaaataatt cgtgaacgta
     9241 ttgttaaaag gaacaatccc acctggaatg cccacgagta ttagatcagg cttttcgctc
     9301 tgctctattt ttttcaaata ccgattaaac atgataatct tctgggtttc cgtcataccg
     9361 ctctcaaaca taaactgtgg aaaagaatgt gcaccaatca gctccccgca tccattagat
     9421 gtgatttgtg acacccgata tccttgtgct tcaagcttct gccgaaggtt aaactgtaaa
     9481 ttaagcttat gcgttcgctc gttcaaccct aatacaaata gaaccggtgt aaaaaaatca
     9541 tgaataacag agcccgggtc aggcggtaaa atatctttcg tgcgtacatc aaatgtattt
     9601 tttaaaatca gcttgtcctc atgctcctca cagggttcga tgaattccat acatgagtct
     9661 ggcaaagtga aattacacat gacttttttg ccaagttgtc cagccttctt gatcacggga
     9721 agatacacct cagctacatc cagcttgaaa ttggatttca ccagtaatat agcatcacaa
     9781 cgctccattt cttgctccaa acaagactct ggcttcacga tgaagcctgt cacttccccc
     9841 ttgtccgtta cacaggcatc tttcccgatc atccccgacc cttgaaaaga aataaggaca
     9901 acttcctcat aacttcctaa tagattcaag ttcctaacta gggctatcgt ttcataatca
     9961 aacggaaaaa tgattaattt attggtcatg gagacacccc tcatgctttt tcaaaatcga
    10021 gaatcgtatc ctcggagaaa tcatagccca gctcattcat catgcaataa tcaagtaggg
    10081 tgtgccgaat atcgtttttg actaccgaac aatgactcag cttcttttcc ttggacaagg
    10141 tatgcaaatc atctgctaca gcaacacaca acgtacaaaa gcggaaattc caacagtttt
    10201 tacatgcatc ctccgtgatt gtccctacat tcaaaatccg gttgatttta tccacttcaa
    10261 agcccgtgtc caccgttcca atctgcacca cttccgactg ctcactgacc cgttcacatg
    10321 gatacagatt tccatgcaca tccgcaaaca atcgctgtac accaggcaca cagggtccgc
    10381 catgatgcgc ctctatcggc atccccgcag aaggctttct ataatgaaac attcggaaat
    10441 atatctgaat ataatagtcc ttaatcagct tcgagacatg gctttcatct actctcccaa
    10501 atttggaaag catcatttta actacctcat agcccctctg ctcaataaat tcattcctgt
    10561 acaaaatttc atccttcaca taagcatcgt taatgtagga ggaccttaca ctgtacagac
    10621 tttcgaaggt ttcataattc gtataaaaat cattgataca accaaaatca ttacgggtat
    10681 ccagcactac attaaaatta atccattcaa agaggtccgg gtaatttctc ttaattttat
    10741 ctacattggc aataatggta tcaaaggagc ctcgtccgtt aacagcaaat cgtctatttc
    10801 tatcatgatt ctcttgatct ccatccagac tgatcgtaag tacaaaacga tgctcatcca
    10861 gaaagtccaa aatatcgtca ttaagtagcg taccgttggt cgtcaaatga aaacctacat
    10921 ctctatacgc cacctgctcc ttgatatatt cgacacattt cttgaccaac gggaaattaa
    10981 tgagcggctc tcccccataa aaaccgaaat ccagacggtc actgtctact gatctatcaa
    11041 tgacaaaatc aatacacttg cgcgctgtct caaaatccat catcagattc gtatgacctc
    11101 gattgtcata tcctcctgaa taaacgcagt aagagcatct aagattacaa ttttgagtta
    11161 cctgtaaggt gagggttttc agctgatgct gaagcatatg ctccaggtgc tttgtcttgg
    11221 gatgattcat aatctgcgga cgctgtgaag ataaaaatcc gttatccaac aagtcacgga
    11281 tatactgctg caattccggt gtagcctcca tctgatccag gttgaagctg gaatgcgaat
    11341 tcagaaaatg ataagcctcc tctttaatcc gcaaaattaa attagtattt acatcatata
    11401 cataatggtg gagtctcgtt tgaaatgtgt atataaaggg ttggcacatg ttcatgattc
    11461 acacctactc tgttttgatg tggacagaag cctggaatgt ccaggctcct ccatacaggt
    11521 ataagcttaa taattaccaa ttccagttcc attatctctg cgataagaac cgtcactttc
    11581 tcgcgatgta ttggagcttc gagtcagact gcctgcgcaa taacaggagc aaggacagta
    11641 acaggaacaa ccacagccaa atgcctcaat cgtgtcgcct acattcgcgc ttcttttcac
    11701 aagcttacgc atgttaaact actcctccca ttcatgatat gatttaaaaa ggtgttcacc
    11761 tatactaatt ccgtacatgg tgttaaatca cactatgaat gcgtttgttt ttttcatcat
    11821 tttatgggga cctcttcttt ctctaatacc catcctctgt attccgcatg acaggtcata
    11881 aaatgggagt gtgatcctat ttgggctggt tcgccgttct ccaacaaaat aactctatcg
    11941 acatgcgcta atatctcgct gcgatgtgta acgatgatta cggtcttgtc acgcaatcgg
    12001 gtcttcaaca atcgctgaac atttagccta gcttctgtgt ccagattgga ggtcacctcg
    12061 tcgagaataa acaatgacgc ttccctgatc aatgcccggg ccatagcaat tttctgtctt
    12121 tgcccacccg acaatctgga gccgttcgag cctatgagga agtcatctgc cgagttctga
    12181 accaattctt ccaggccaat ctccgcgata atagcctcta ttgcatcatt agtgacttct
    12241 gtgcctatgc ggatgttgcc aaaaatagta gtatcaaata aatacacctg ctgactgacc
    12301 aaagctattt gacttcgata ctcatctatt tcatagcttt ggatgtcaat gccgtcatag
    12361 gtgattatcc cctgatcagg ctggctgaat ctcatcatca aatccagcag cgtagacttc
    12421 cctgccccat ttgctccaat gatagctacc ttttcccctc gggcaatcct aaagttcacg
    12481 tcggatagga cgggttcatc cttggtataa gaaaaagaaa catgatgaaa tgcaatgtga
    12541 tcttcgaatg gcggctcagt tagtatagac gctggggtga ctgaattaga tgtctcttcc
    12601 tctgcccagt ccaagaactg ataatatcga atggcggagg gaacgacttc agccagcatg
    12661 tagccaatgt ttaaaatagc gaaaacagga gtggtaacat aagcactgta agaaacaaag
    12721 gcaaaaatcc cccctacagt gagctgtaaa cgaaagataa gattagctcc cacaacgtac
    12781 acaagcatca ttagaagctg aattaaaata gattccgaag cgatattcca ggcgtccaga
    12841 agtgacaatt tccgttctga atctacaatt cgacgctgct tggttgagaa ctgctgatgc
    12901 ttatgtggaa taagaccaaa cattcgctgc tccttcatgc ccccgacaga ttccccaaac
    12961 cactgggcaa aatcactact gccttcaata aaatccccta ccagtttttt tctacgcttc
    13021 acaaagtact tcaccacaac atatttgatg ggtaaaaaaa gcagcacgat tacagtcatt
    13081 ttccagttaa tgagcagcaa accacataaa ccaccaatca tgctgaacgc ctgcataatt
    13141 acaaaaaata ctccactatc tgtgatcctt gatacattgc ctacatccgt gccaatttgg
    13201 ttcagcaact ccgcttcatt agttcggtta aaatagctca ttcgtactct tgtcagatgt
    13261 aaatacgctt tttcaaataa agaaaaggta acctgtgcgc ttaaacctgc ccgaaaggtt
    13321 tctttacaca cattcagcag cttgtccaag caaacgatta aaaacgcagc agaagtgtac
    13381 aggattacag cctgcatatt ccctttcaga agaccttgat ccacaataac cttgcttgtt
    13441 aaaggcaata atatattcaa gcccgctgat aggatgagac atatcaaaat gatagtgacc
    13501 gtcttcagat aaggcctaaa tgttgccacc agacgtttat atactatgga ttctttcatc
    13561 cttttccccc tttcatcaga tgtaccttct ccccctatta actaattccg tatcagaatc
    13621 aaaatcacct taaaacatct tttaactgtt ctagtaattc catatttacg agattaaata
    13681 tgatttatgt cattcttgaa aattggaatt aatgtatatg attggcacat acaaaaatca
    13741 cttatttttt tatccgtcca aagggggctt gaacaaatgc cgaccacgat ggttatcgac
    13801 tgttgcaaag aggatcagtg cagaggtagt tccagatgct tttacagaaa aatttgtgaa
    13861 ctttatctga gcgaggtata ccgtttctgt atgcatttag tcaagaatca gtcttgcttt
    13921 acatttatgg cagaagaatg tacacaagat acttttgtag cggcaagaca gcaactggtc
    13981 aagctcaaac aacaccccaa tgtaaaaggt tggctgtacc tcacggctaa aaatcttata
    14041 tataaatcat ttaggtgcta ctatacacaa aaaaagcatg aaactacgct tgaatgtgag
    14101 aagatctgta gttattcaaa ttcggtagag gaggagtggg aaaatcgtag attgggagat
    14161 gtggatacgg ttatcgttaa tatactaatg cagctttcca acaatgaata tacgctctat
    14221 gaagactact tttgtcgaca actggctgtg cccttccttg ctgtcaaata taatatttcg
    14281 gttacggcta caacgactcg aatctataga ctgaaaagaa aacttcgtac attgtcccat
    14341 caatattgcc taactcatat ataaatttat ccatgaaagc aaaaaagcgg agcccctctc
    14401 ccaaagggaa gctccgctgt ccgttcttgt gactatgaat tgtattcaca ctacacgatt
    14461 acttaatccc cgaaatcgta tagttctcaa taatatactt ttggaaaaca atgaagataa
    14521 tcatgatcgg aacgaccatg aaggtcgaac ctgccatttg cagggcaaat tggctttcgt
    14581 tctgtccctt aagcagtgac agtccgacgg acaaggtgta cagcttctca tcgttcgcaa
    14641 taatgagtgg ccacaagaag ctgttccatc cgccgatgaa ggtcaggatg gcctgtactg
    14701 cgataattgg cgtcgaaatg ggcagcacaa tttgtagaaa agtgcggaat tcccctgctc
    14761 catccagacg tgtcgcctcc agcagttctt ccgggatatc ggacatgaac tgccggaaca
    14821 ggaagatcgc gaacgcgcct accaatccag gcaggacaat ccccagcatg gaattggtca
    14881 atcccatctg gttcagaatc aaatagacgg gaatcatcgt cacttgacct ggaatcatca
    14941 tcgttgctag taccagatag aacagaaacc ctttgccttt aaattggaat ttggcaaagc
    15001 cataacccgc catggcattc aggaataatc cgaagaaaga agctaaaaca atgatcagcg
    15061 tattcgtcag ataggttcca aaagccatgc tatcgaatag taatttaaaa ttatccagtg
    15121 taaaatgctg cggccagatg gtcgggggaa tttgggttac ctcgccctca gtcttaaagg
    15181 aggataaaat catccacgca aaaggcagca ccatcaacag acctcccacg gtcaggagag
    15241 tcgccacgaa ccattgaaat gttttttcac cactgcgcgt attggcgcgg gcttgctgaa
    15301 cagctgtttt cacgttcatc acctctctct atcaggactc cgctttattt tgcaaacgga
    15361 actgaatcag cgtcaccgca atgattgcga agaacagaat gaacgatccc gccgcggcat
    15421 acccgaattt actaaattgg aagccgttat tgtaaatgaa cagggatgcc gtcagtgtgc
    15481 catcgagcgg tttccctttg gtcatgacaa acggttcctc gaaaaattgc agccagccga
    15541 tcatcgttgt gatggacacg aagaaaatag cgtaacgaag ctgcggaagc gtaatataac
    15601 gaatttgctg ccatgtattg gcaccgtcaa gctgagccgc ttcataataa gaacccggaa
    15661 tccctttaat agccgcaata aagataatca tgtttaagcc gatgccccgc caaactgcta
    15721 acacaattaa cgaaactttc gcaactgttg gatcggtcaa ccatgggacg ggacctaaat
    15781 tcatcaaacc aagtacatag ttgaataatc caagcgtcgg attatacaag tagctccaaa
    15841 cgaccgcgac cgcaactaca ttcgttacgg acggtagata gaacacgacg cggaatactt
    15901 tgaaagcacg tgatttaccc atgttaatca gaatcgcgat gctaagcgaa aatatcagca
    15961 ccaacggaac acctatgatg acgaagaaca gggtattacc aagggacttt ataaaggaag
    16021 ggtccaatag tacgtttgta taattttcga gacctataaa gcgaatacta tcataattaa
    16081 cgagtccgga cagatccata tccgtgaagc tgatcacgag cgccagtagt atcggcaaca
    16141 gcgaaaacag cgttaacagg atgatggagg gaccgataaa caagtatggc gcaagcttct
    16201 gcgagcttcc tttcatgcct tcactccctt tgacaatggc ggatatggat cattattttt
    16261 tcataatact tgcagcctgc tgattaaagt catccatttc cttttgtaca tcggcatgac
    16321 cgcggtaaat acgctcgaag ctcttgataa attgttgaga aacctcttcc catgcagcca
    16381 gttgcggcaa tgctgcggaa tgatctagct gtttgcgaat cgtccgaagc atcggatcac
    16441 tcttcagttt ggcatcttcc cacgatttag tagtcgcagg caagttactg gacagatcca
    16501 tccatttcag ctgcgtttct ggtttgctca tgtaagccag gaatttggct gactcctctg
    16561 gatgcttgct gaatttcata attgaaaggt tggcaccacc caaaacggac aggttgttta
    16621 cttttccagg aagctccgct atattccact taccttccag ttctggtgcc ttgctcttga
    16681 tttctttaat catgaaaggg ccgctgataa acattggaac gatcccctcg ccttgcaaac
    16741 cttgaacgga gtcaattcca atatccactg cgttagagcc attttggaaa aaggtattta
    16801 catacttcac agcatctaca aacggtggtt ggttgaacag cggattgccc tgctcgtcaa
    16861 ccagtttgga accgttctgg agagcaaaca taaagcccat agactgctcc tttgcactaa
    16921 aggagatacc atatttgcct ttgccccgag ccgccagctt ttgggcagca tcggaaagct
    16981 cttcccacgt tttaggtgct tcattatatc cgacttgttt cagcaggtca gaacggtaga
    17041 acaaaactct cgtttcagtg taccaaggca caccgaccgg ttttccttca aattttgtcg
    17101 tacctacagc accctcgaag aaattcttcg attccagctc aggatacttg ctgatataag
    17161 gggtaatatc cgtcaatgca cccgcagacg caagttctgg aacccatgat gtacctaact
    17221 gaaccacgtc cggaccggat tttgaagcaa ctgctgtcag cagcttatcg tgagcgttat
    17281 cccaaggcaa cgcctgtacc tcaacatgaa tatccggatt ttccttttca aaacctttca
    17341 caatttcagg cagcagcttt ccttccgctc ccatacccca taaggtgatg gtcgtcttgc
    17401 cactcgcatc tttgccagac gaatcatcct tggacgagca gcccaccagc gcgcccccca
    17461 gtaataaggt acttgccaaa atgatcccta acgttctttt catcatacga attcctcccg
    17521 agatgaccgg tttaccgatc atgcaatatg ataacggatt caaatacgag gactttgcaa
    17581 aaattcaata agcaacttcc aatgaacatt atatagaacg aaatggttta attcgtccat
    17641 atattgcact ttgaaacgac aagaatcgaa ttttgtaaaa tcctgatgca tgtaaatacc
    17701 tagcgattaa agcataccgc tataacactt atgttcaaag cacaaggacc atacccttca
    17761 atagaaacgt ttcgatagtc attatagaac aaattgaaac cgtattcaat aggaatatta
    17821 ttttttattt gttcagaata ccaacttttt ttcatatata tcatctttat tacgttattt
    17881 aacctatgaa aagaccctga attggatttg actctgtatt tgaaagcgta tataatccaa
    17941 ctgagttcaa taatagaaac gtttcgatta ataatacgac agaacattat gcttctatac
    18001 tagctattag cctttttagc acttttttga atcatcttta tccaaaaaat ctcatgaatc
    18061 tgaaaaagag agctgtccac caacaataca gcttatggag gattatgatg gaacaacacc
    18121 tgaattccta tttagaaagc atgacgcttg aagaaaaagt tgatcaactg ctacagcttg
    18181 taggtgcctt ctttgaagaa gcgggaacag atagtcaaat taccggccct atggcttctc
    18241 ttggcatcac agagaaaaat gtccataacg tcggttccgt gcttggcatc gcaggggcca
    18301 aggaagcaat tcgtgttcag caggctcatt tgagtaaaaa ccgtctgggt attccgcttt
    18361 taattatggc agatattgta catggcttca aaacgatttt ccctataccg ctggctattg
    18421 gttgctcatg ggatatgcgg ctggcagaag agagcgctac cattgctgcc cgcgaggcgg
    18481 ctgtatccgg tgttcacgtc acattcgccc ctatggtcga tctggtgcgt gacccgcgct
    18541 ggggccgtgt gatggaatct actggggaag accctcatct caacagtcaa tttgcccgtg
    18601 cgtttgtgcg cggatttcag ggtaaagatc tgacgaacga taccgaccgg gtggccgcat
    18661 gcgtgaagca ttttgccgca tatggagctg gtgaaggcgg acgggattac aacactgtag
    18721 atgtatccgc atggcagctg cgagagtatt atctcccctc ctacaaagct gccttagatg
    18781 aaggctgcga aatggtgatg acgtccttca ataccgtaga aggcgtagcc gcaacgggca
    18841 ataagcgcct gatgcgtgat ttgcttcgtg atgaatgggg ctttgatggt gtactcatct
    18901 cggattgggc cgccatcaag gagcttatcc ctcacggcat cgccgaggat gagcgcgagg
    18961 cagcgaagaa agcactgctg gctggcgtag atattgaaat gatgacctcc tgctataacg
    19021 ggcatctgcc tgaactggtt cgcagcggac agctggatga agcgctcatt gatgaagcag
    19081 taatgcgtat attgaagctc aagcaaaagc tgggcttgtt cgaaaatccg ctacgcggcg
    19141 cagaccctga gcgtgaacgt gaagttgtgt tctgtgaagc tcaccgtacg gttgccaaag
    19201 aattagctat taaatcttgc gtgttgctca aaaatgattc cgttcttcca ttgaatcgca
    19261 atcaacatat tgcgttgatc gggccttttg cagagagtgg tgatatcttg ggctcttggt
    19321 cgtggagcgg ttcgcaagag gaagctattc gcgttgttga cgggttccaa tcgaaaatat
    19381 cctcctcgct gctcacggtt gcgacaggtt gctctatcga cgatataact gaggagcaat
    19441 atgcagaagc tctgcaagtt gccagccaag cagaggttat cgtgttggcg cttggagagc
    19501 gctcggatat gagtggtgaa gcaggcagcc gttccaatat tcgcctgcca caagcccagt
    19561 tggaactggt gaagcgcctg aagacgctga acaagcctat ggtagccgta ttatttaatg
    19621 gtcgtccgtt ggatctgcac ggtgttattg aagaagcaga cgctgtactg gaagcctggt
    19681 tccctggtgg cgaaggcggc gcggcgattg ccgacttgtt gtacggtgat gccgaaccta
    19741 cgggtcgcct gaccatgtca ttcccgcaat cggtcggaca ggtgcccgtg tactacaatc
    19801 attttaatac aggacgcccg cagttagatc cgaatacaaa agaacgttat gtgtctcaat
    19861 atctagacgt accgaacgaa cctttattcc cgtttggcta tggactgagt tataccgatg
    19921 tcgcttatga tagcgtacag ctttccggcg atacccttat acctggtcag gaactgaccg
    19981 tgaaagtgca ggtaacgaac acaggaacac gtccagtcga agaaaccgtc cagttctatg
    20041 ttcgtgatat cagcggtgat acggttcgcc caatgaaaga actgaaagat ttctgcaaag
    20101 tccttcttgc cccaggcgaa agccgggaag tggaatttgc attgaccgag cctcagctgc
    20161 gctatcatca tgcagatttg agcttcagca gtgacagcgg tgaatttgcc gtctttacag
    20221 gacctaacag ccgagatacc agcgaaagcc gttttcggtt agtgaaataa acaagaaagt
    20281 gaggcgttcc ctttgatgaa tacaagtctg gatcaaaata ttttgctgcg ggccggcgac
    20341 ctgtctttta ccttcttgag cagcggtgat gtgtataaga tcgcccatgg ctcaacgatg
    20401 atcaaccagc tgttgaccaa ttcagtcgat ggttccctga acaatctgta cttgagattg
    20461 taccgtccat ccggtgtaag tatcactccc ctgcttggag ttcgctcacc gggagtcatc
    20521 cgacaaacag atcagcagat tatttgggaa ggtttcaccg ctggtgtagg ctatcaggtg
    20581 accttcacgc taagccgcct gggagtatgg ttctgggatg taaccctaca gggcgatgac
    20641 gtggaagcag atgtcgtgta cggtcaggat atcggcattg ccgataccgc tgctgtacgc
    20701 agtaatgaag cttatttgtc tcaatatatt gaccacaccg tctaccataa tgaacaaaga
    20761 ggctatactg tttgctcacg tcaaaaccag cctcaaagtc agacattccc atacattcaa
    20821 caaggctcgt taacccgcac tgttggttac tcgactgacg gttttcagtt ctttggacta
    20881 tcgtacaagg aaacgaatga gccggaagca ctccgtcgcg actcgctcgc caatgaagta
    20941 tgccaatacg aattcgccta taccgcattg cagtccgagc gagtggaact tgccggggaa
    21001 gctcgcttta ctttttacgg tcttttccag cccaatcatc cagccgcagt gacaaagctg
    21061 gagtatcagg aactggtgac aaaggcacgc gacgaagtaa ctgccgttct agcagacgcc
    21121 tctgagacca gcataccgac acacgcggca agcgatcttc aggcagggcg tgtggctcca
    21181 gctcaaacca tcggtgagcc gctgcgtacg ctggacttca ccgatgccga agtgaatcaa
    21241 cttttcccca aacggcagga agaagaatgg gatggcaata aactcctttc ctttttcacg
    21301 gacagctatg agcatgttgt actcaaatcc aaagagcttc gtgtagagcg tccccacggg
    21361 cacattttaa tgggcgggca ttactcagga ggtaaggaag aaaccattac aaccacctcc
    21421 tatatgtacg gagtgttcaa ttcccagctc gtaat
//
