LOCUS       NZ_JAFJXZ010000017     33511 bp    DNA     linear   CON 03-JUN-2024
DEFINITION  Paenibacillus polymyxa strain Hob6 Scaffold_17, whole genome shotgun
            sequence.
ACCESSION   NZ_JAFJXZ010000017
VERSION     NZ_JAFJXZ010000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 2906550)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Draft genome sequence of Paenibacillus polymyxa strain Hob6,
            isolated from hemp (Cannabis sative) seeds' oil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2906550)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2021) Plant Science Departement, McGill
            University, 21111 Lakeshore, te-Anne-de-Bellevue, Quebec H9X 3V9,
            Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-JUL-2020
            Assembly Method                   :: SPAdes v. 3.12.0; Medusa v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly :: GCA_000507205.2; GCA_014706575.1;
            GCA_000164985.2; GCA_000597985.1; GCA_002893885.1
            Genome Coverage                   :: 266.29x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017589695.1-RS_2024_06_03
            Annotation Date                   :: 06/03/2024 02:57:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,275
            CDSs (total)                      :: 5,119
            Genes (coding)                    :: 5,024
            CDSs (with protein)               :: 5,024
            Genes (RNA)                       :: 156
            rRNAs                             :: 21, 9, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 19, 2 (5S, 16S)
            partial rRNAs                     :: 2, 7, 15 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 44 of 95
            Pseudo Genes (incomplete)         :: 63 of 95
            Pseudo Genes (internal stop)      :: 13 of 95
            Pseudo Genes (multiple problems)  :: 21 of 95
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2873039
            Orig. end                         :: 2906550
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAFJXZ010000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..33511
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="9"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..33511
                     /SMILES="C([*])C(-O)NC([*])C(=O)NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..33511
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>33511](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>33511
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..33511
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:28640](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      20001..28640
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     gene            1059..5060
                     /locus_tag="JYU28_RS23870"
                     /old_locus_tag="JYU28_23910"
     CDS             1059..5060
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820906.1"
                     /locus_tag="JYU28_RS23870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23910"
                     /product="GH32 C-terminal domain-containing protein"
                     /protein_id="WP_069012405.1"
                     /transl_table=11
                     /translation="MRKVKRGKCWISGMVIWAMVLQLVVPGISVASENRTVAGETLIPK
                     NDVKSSVTDAIYQIKNIPKNDMGLSVTDSVYQIRNPGFETGDLTGWTVIKGDAFGPNSV
                     TDETTWWAEKIPYNQEGAYHLNGWKYDESATGVLRSSTFELGGSGWISFKLGGAKNPDK
                     VFINIVEVDTGQVIARYGNSAFADVGFPDPAQGMRLANMVQYKADLSTQLGKKLYVEVV
                     DNATSDWGVIFADAFSMYHESEPAEGIVATDIKPDFKRYEIDNPSFETGNLDGWTVEED
                     AFEVTDEAHASKEGNFYAKSSLQGKGSITSNTFTLQGTGTINFTVLDILKPENAYVALF
                     DANSNTLLMKTGNVSANEKILWKVQEHYNKKLYVKVVDHSNEASIAVDSFQASGRGTIF
                     YLNLDEGAGKKALEKVHDLKHDVNYVFNNARYMASKDPRWTPRGIKGGALLFDGYSNYI
                     EVNANDTVPISDALTIEAWVAPRSYEWGDGNKLSAIVNQSDQDKAEGFSLGMYRHGTWS
                     MQVGISGQWIQVWVKDHPLEKYKWNYVAATFSKEDGKIKLYLNGEEVASQVTPLNVPIT
                     PSTESLIIGKNNKPVELAGVFSFNMFSGLLDEVKLHNKALTNQEILAGYESVKALHGGA
                     IPKIPNADIDEDPSVFGGDQHRPQYHAMPPQNWMNEAHAPIYYNGKYHLFYQHNPQGPF
                     WHQIHWGHWVSDDMVNWENVRPALAPEAGTLDPDGTWSGSAAYDRNGNPVLFYTAGNDS
                     LSPNQRTGLATPADLSDPYLEKWVKYPKPVTEQNGKGIHNEFRDPFVWYDKEVDKWYQL
                     VTSGLPDFSSGTALVYVSDDMYNWEYKGPLYVSDRSRYPELGTVWELPVLLPLGTDSTG
                     KQKYIFMINPHEKPEHVPPANDVQRDVEVFYWIGTWDRDNFKFIPDQEAPSKMDVGDGY
                     LTAESGLVTPDGRTVVFSMVQNVRTPQAEYQSGWAHNLSLPVSLSLDNHDKLHIEPIKE
                     LQSLRGKKWVDFSDKNLESANQLIQNVKGDMLEIVMEIDPREAQKFGLKVRRSEKGQEE
                     TLIYYDKKNGTFNVDRTKSSIDPDVRVDGIQGGYVDLKGENLKLHIFLDRSVIEAFANY
                     KKKLTTRVYVGRYDSLGLQIWADGDINIKSMQVWDMNALTGKPAAPVYVPDKWDNSVYK
                     DITELPNHDFATGDLTGWMTEGDAFQNVHVTNTQFFWDNIYFNPSHKIPGGYHLWGFNE
                     QAGGDSLTGALRSQNFVLGGNGKINFLISGGRDIDRLYVALVRASDGKELFKETATNYE
                     EYQRKIWDASDYIGEELYIKVVDHSKGGFGHINVDDFNVPVQVKKKTNN"
     gene            5379..7010
                     /locus_tag="JYU28_RS27150"
                     /old_locus_tag="JYU28_23915"
     CDS             5379..7010
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /locus_tag="JYU28_RS27150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23915"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_039274859.1"
                     /transl_table=11
                     /translation="MYKELLSIAQLMGETMRLVGYARYYKSLNIDGLHYIHQVEGTQVI
                     AIVKPNHSTHHEATTFLMNLLLTEKLKMNTVTGHAQNLKKFLDYMMFWRLEEDFEHIHN
                     IEVKAGGPYPIEVILLGFADYLRCIPKGYKPFEDLKVATHGIHWSMLKNIPLNKHAMAE
                     GKLSTVIRSSHNDLKKTNWCEYPSGALAPIIYTACAYLKFLRDRTTRFKYLPLEQVPRK
                     EIRDNHSLIAGTAGSRVRIVFDVENIARDSGTAGPGGGKSRQASPINHDKVFSETEADM
                     FFELIDPYENALDLLLFAILRYFGLRPGEAAEIRIEPSTIPSNLNVYHTAREELTESLS
                     GNLQFVKERGLRGNWVIDTGWKTKASCRDVALITHKTIDPFSRKNIRFPTQEEFTDLLY
                     WALLQRRELLSYYTSEDHGYLFVSESNNSKGKPLSKKGVYSKYNNLADDLFQRTGGSVD
                     LRSYYPHTFRHLFATSLLLRYRRPIEEISKWLGHSSVVITRDTYIHWIPESNNDTEKGK
                     VDHLGRVFMRQAEISEGIHAHEEDSE"
     gene            7007..7642
                     /locus_tag="JYU28_RS23880"
                     /old_locus_tag="JYU28_23920"
     CDS             7007..7642
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JYU28_RS23880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JYU28_23920"
                     /product="hypothetical protein"
                     /protein_id="WP_069012404.1"
                     /transl_table=11
                     /translation="MTLEWTPLSEFRKFLKNTLRLNHVNQVFSSIKNPVLQLFTTFPAP
                     DNWLAVPPEERPTFRHRDSRDLWYVIFWAWHTGFCKGNDVVAQYRRNDLVCYLSTRGRV
                     NLSDFPVKMGLLKNSEAEHIRKKDSNRIGLFNKLSIHLLGVMKPLGDFTEEDIALADVM
                     RPNDKRYNAKCLKDILFELGYSDEPGRRRQRILFDDCCEHPKWGGYRT"
     gene            7563..9056
                     /locus_tag="JYU28_RS23885"
                     /old_locus_tag="JYU28_23925"
     CDS             7563..9056
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JYU28_RS23885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JYU28_23925"
                     /product="site-specific integrase"
                     /protein_id="WP_176715753.1"
                     /transl_table=11
                     /translation="MNQEDVGKEYCLTIAVSIQSGGDIAREFREHLKRSNSLDYYIRKA
                     GSALHKFFKWLDQHGESDASSLEYEDFLDLFDYISKNNDGEEFSAKYTGNNLLHIKLFF
                     DWGKGSHTFFPTYVDWPSDLYSGIHREAQEETYSGDGLAFDDPNFPMLMKEAIENYHPE
                     DDVEVLCRAFWLIIASSPVRKTYLLNLQAEECMLPLPNAPSAVGLYSPYSGIEKAKHRN
                     GQFPIIDSAGLRAVEFLQKRSSDKAFRPIRNERADASYVHLFQLEKYPWILNERQIYRF
                     FDKIAEFIGHGDKKGKAHGYRHYLITHIAIETGNSELARLAAGHENQTMLNRYLRSNLS
                     RQALLFATIKKYQDGEIAGRFIWRIFEALASEQTEPDELIKALGSEELSLDEFFAKFGL
                     PAPTGVGRCLIQGACLFEAKCFSCHHFAIRKSEAAQAFHTLARLTKDMWNMMRGSRDFT
                     TKNAKAAGLATQIALLGDMIRHFGYSDEQIQIEVISRLV"
     gene            9082..11457
                     /locus_tag="JYU28_RS23890"
                     /old_locus_tag="JYU28_23930"
     CDS             9082..11457
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JYU28_RS23890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JYU28_23930"
                     /product="site-specific integrase"
                     /protein_id="WP_069012402.1"
                     /transl_table=11
                     /translation="MSQILAWQSLRFGPITVRRKGQFESREHLTRSEYEQYRSAETWGR
                     VEPILSSSLTDLVQPTIFFKLPGTQRDYVLLLAFLQRISLPLEIVFPTKTEFNKFPFPE
                     LPNFEYFDALYDKYYPVLYPMDSEKQLQKAKKRIPLLRTVVCLWFAGYALKEGLEGNHI
                     ITSSVLAKASKIAKYHRSSLTLLGKMLAKETDSLIENKPVIPCDEAERSVWIAAGIYPT
                     QTPFEESLYTFAFSYLRQRVNDSITDDYYDDEGNLLFRYGKKTISINYWKAIVKYIRYF
                     AIKCRSKGLTDISENSISEVYTEIFGQMKGQEDKTFFRVALRHWLRWLIRTTNASYNIE
                     RIMPRPRRVMSKDHGRVFSMSKAYILVQTLMNDQTPLINENILMDFRHRRACLLMLSTA
                     ARPHEIVNLLQNALFIDSQDNSWIRFHKTKTIRNQPDRNGYEWVHHALVKSDAARWFNE
                     LIHFAPSEPIFFPREWGGDGLTELRLLASKHNDGPIRTSGLYNFLTRIQSKLWPELRKP
                     YFTPHNLRALHLTYRRILGDNDELLERQAGHSHPSSKKPYTETMPAEEVAKFGHLLQKG
                     VWRKKPEGEDADKTEGAGISSTEYVAIDEITEISSKFEVTPQKLDEAYKLTQKIIEESP
                     RFQGKFIDLEDELHEVNVGGYTHNCNAHVLLNCGHTPGHCRACDDYSPDEGTEDAHKAD
                     IFREMLHYYYCLDAEKNFKSTGQRKMVFQKAEDIKERLNKTERSLWVNKFKMPPNEAKK
                     LHSLLFKKAKAYFREQSKEKPNPTNAEVLCYILSGEVK"
     gene            11459..11902
                     /locus_tag="JYU28_RS23895"
                     /old_locus_tag="JYU28_23935"
     CDS             11459..11902
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JYU28_RS23895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JYU28_23935"
                     /product="hypothetical protein"
                     /protein_id="WP_023988780.1"
                     /transl_table=11
                     /translation="MARPVSFSSSDLAWECAQVKRKLLNDVKKGRLSRLSKSDVYDMIA
                     KRPRIRLKSSRMLWTGSYKEYLEKWFTKLNEEIQLILDSASEGEPTITSPEIVAQEHRE
                     LQAKVTHLTQLISTYKDALDELRIENGQYRELISQRFGDIDLF"
     gene            complement(<11902..12235)
                     /locus_tag="JYU28_RS23900"
                     /old_locus_tag="JYU28_23940"
                     /pseudo=""
     CDS             complement(<11902..12235)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003392931.1"
                     /locus_tag="JYU28_RS23900"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="JYU28_23940"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSKQELRQFVKEHNFQSAEDIQWTLKELFADVLQEALEAELDTHP
                     GYEKHDVKTNKRETAATATTVRKP"
     gene            12354..12845
                     /locus_tag="JYU28_RS23905"
                     /old_locus_tag="JYU28_23945"
     CDS             12354..12845
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021498.4"
                     /locus_tag="JYU28_RS23905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23945"
                     /product="Wadjet anti-phage system protein JetD
                     domain-containing protein"
                     /protein_id="WP_141695516.1"
                     /transl_table=11
                     /translation="MYGIELQMGESLPERLFFGVTVHSQLMKAGRVIDLRAERILIIGN
                     KTVFHEYIQSLSRIGNLLEKKIIVVYLGGFPGPDKRFFLRQIQDKFDKNGLQIEVQFWG
                     DIDWGGFQIFRHLQKSVFPQLRPYRMDKTTFHQHLDWAETFTADYQVKLEQLLENTDNS
                     "
     gene            complement(13342..13704)
                     /locus_tag="JYU28_RS23910"
                     /old_locus_tag="JYU28_23950"
     CDS             complement(13342..13704)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /locus_tag="JYU28_RS23910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23950"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_069012401.1"
                     /transl_table=11
                     /translation="MSELKTIIGYKIREIRRARSLSQEQLGEKVDMSQSYIGEIERGEV
                     NVSLETLDKLTRALDVTMLELLRLENIQLDSIRSNKMTVIQLLQELLIQKSLEEISMIY
                     RITNDIFETTGGTKNK"
     gene            13847..14101
                     /locus_tag="JYU28_RS26680"
     CDS             13847..14101
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JYU28_RS26680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_081317608.1"
                     /transl_table=11
                     /translation="MNVLPTQSVIENVLQYKMRGKVAYLGHVTASVAVNLTYVKPYNDP
                     SGKGYQRPVDPKRCHDFSLYLSKGDDALFTPVLLNANSQ"
     gene            <14141..14839
                     /locus_tag="JYU28_RS23915"
                     /old_locus_tag="JYU28_23955"
                     /pseudo=""
     CDS             <14141..14839
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025438.4"
                     /locus_tag="JYU28_RS23915"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23955"
                     /product="DGQHR domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="RLICKGKASLMDGQHRLGGITKYIKETNSELNVPFLAFHCLDEDE
                     EIRLFDVINTKAKGIGSSLSRFLRRDSDELSWVATELMVQNSSPFFSIGSIIGKRNKDR
                     HITLQNLYKTLHYLTKEPRIASLSKEEKLSLSLSYFDSIRQTFENEWSNYKDYRLTHIV
                     CLDALSIAGSGILDRAVHNQNKRFDYALIEKAVKKLKRVDWSMNGPLKYLKGLPGSRSL
                     AEELKEQMLK"
     gene            14858..15193
                     /locus_tag="JYU28_RS23920"
                     /old_locus_tag="JYU28_23960"
     CDS             14858..15193
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JYU28_RS23920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JYU28_23960"
                     /product="hypothetical protein"
                     /protein_id="WP_069012400.1"
                     /transl_table=11
                     /translation="MSGTNRRVESLVIVDPEGNLQPFHFIDHYRENDQFYCILRHYNEI
                     KIFKLVEKDGESVLFMAPLCDDDSTVVPTEYKIAGISFDALTTDSQLSCKFQVSQNGKS
                     INIQEYL"
     gene            complement(15479..16366)
                     /locus_tag="JYU28_RS23925"
                     /old_locus_tag="JYU28_23965"
     CDS             complement(15479..16366)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="JYU28_RS23925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23965"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_208332719.1"
                     /transl_table=11
                     /translation="MSVTREEVLKSATRLFKERGFLLTTIQDIAEDCGIAKGSVYKFFP
                     SKEDLFSEVFDQCHNDYFDQVDELTRLPGLSPEEQFIQQIILRFRYFIEYKHILVEFTE
                     LPIQQDPKFHPLRHKVRGRLIRWHSECLLHVYGEEIHPYLWDLVSIYRAILKEYLFWIV
                     YEEKSLSLEETAKFIFDKLNVLVKHMMASDPKPLLKQASFERYLNWGLGNRQGEKEQIL
                     TELFREMDSALNILSSSAKHRSELSELCHFIQTEVRKAEPNLPLLQASLYYLEREKELK
                     SLVIQLRNIIYSGI"
     misc_feature    complement(16385..16401)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.16"
                     /tool="antismash"
     gene            16493..17065
                     /locus_tag="JYU28_RS23930"
                     /old_locus_tag="JYU28_23970"
     CDS             16493..17065
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017815404.1"
                     /locus_tag="JYU28_RS23930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23970"
                     /product="hydrolase"
                     /protein_id="WP_025723565.1"
                     /transl_table=11
                     /translation="MEKLLDPQKTALVVIDLQKWLGNQYAPYSAEQVVSNAAALADAFR
                     EQGSMVALVRVSSKDLKDIPRPKLDSPAPPLNLPEGWDQIVPEMRVAETDHIITKKQWG
                     AFYGTELDLQLRRRGIDTIVLCGIATGLGVDTTAREAFMNGYQLILAIDAMTGFSQAEH
                     DHVKNFIFPRIGRVRTTQEIISAFAEV"
     gene            17171..18607
                     /locus_tag="JYU28_RS23940"
                     /old_locus_tag="JYU28_23980"
                     /pseudo=""
     CDS             17171..18607
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="JYU28_RS23940"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23980"
                     /product="MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYPWYVLSVTSLGAFLVLVNIGTLNVALPELSQQFHANAAASSWI
                     LLSYMLVNTILILIFGQISDIFGRSRMYLIGMAIFTVSSLLLGYAFNVEVLILLRIVQA
                     AGGALVVTNTTPLITDAFPQSQLGTGLGLNLLSASVAQVLGPVVGGVVTTA"
     gene            <19099..20008
                     /locus_tag="JYU28_RS23945"
                     /old_locus_tag="JYU28_23985"
                     /pseudo=""
     CDS             <19099..20008
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (0-232). E-value: 1.8e-51.
                     Score: 167.1. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23945_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430446.1"
                     /locus_tag="JYU28_RS23945"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="JYU28_23985"
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /pseudo=""
                     /sec_met_domain="Aminotran_3 (E-value: 2.9e-49, bitscore:
                     165.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KRTGIFAFMGGFHGMSLGSLAVTSNIQKRSSSGIALSDVTFFPYS
                     ESPIDSFDTIEYMEAVLNDGHSGIEKPAAIIFETIQAEGGVNIASPEWMLRLRELSDRH
                     GILLICDDIQVGCGRTGPFFSFERAGMIPDIVLLSKSISGYGLPMSILLMKPELDVWKP
                     GEHNGTFRGNQLAFIGATAALEYWEMNNLEQSVKYKEAFVREYLTKQILSLHKGLTIRG
                     AGLIWGIDFFQCGG"
     aSDomain        19301..19996
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23945_Aminotran_3.1"
                     /evalue="1.80E-51"
                     /label="JYU28_RS23945_Aminotran_3.1"
                     /locus_tag="JYU28_RS23945"
                     /protein_end="232"
                     /protein_start="0"
                     /score="167.1"
                     /tool="antismash"
                     /translation="KRTGIFAFMGGFHGMSLGSLAVTSNIQKRSSSGIALSDVTFFPYS
                     ESPIDSFDTIEYMEAVLNDGHSGIEKPAAIIFETIQAEGGVNIASPEWMLRLRELSDRH
                     GILLICDDIQVGCGRTGPFFSFERAGMIPDIVLLSKSISGYGLPMSILLMKPELDVWKP
                     GEHNGTFRGNQLAFIGATAALEYWEMNNLEQSVKYKEAFVREYLTKQILSLHKGLTIRG
                     AGLIWGIDFF"
     gene            20001..28640
                     /locus_tag="JYU28_RS23950"
                     /old_locus_tag="JYU28_23990"
     CDS             20001..28640
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (3-426). E-value:
                     4.2e-184. Score: 604.3. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23950_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (536-823). E-value: 1.6e-104.
                     Score: 341.4. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23950_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (919-1136). E-value: 3.6e-33.
                     Score: 106.8. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23950_PKS_DH2.1"
                     /NRPS_PKS="Domain: PKS_KR (1427-1621). E-value: 1.5e-61.
                     Score: 199.5. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23950_PKS_KR.1"
                     /NRPS_PKS="Domain: PP-binding (1731-1794). E-value:
                     1.8e-12. Score: 39.4. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23950_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1828-2113). E-value:
                     3.8e-93. Score: 303.7. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23950_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2281-2686). E-value:
                     4.6e-100. Score: 327.0. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23950_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (2793-2861). E-value: 2e-24. Score:
                     77.6. Matches aSDomain: nrpspksdomains_JYU28_RS23950_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="JYU28_RS23950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23990"
                     /product="hybrid non-ribosomal peptide synthetase/type I
                     polyketide synthase"
                     /protein_id="WP_069012549.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 6.4e-88, bitscore:
                     291.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.8e-182, bitscore:
                     604.3, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7.1e-103, bitscore:
                     341.4, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.6e-50, bitscore:
                     168.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.1e-73, bitscore:
                     244.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5e-110, bitscore:
                     365.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.1e-13, bitscore:
                     47.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKIAIIGIGCRLPGGIRGPEEFWEALTAGKDMTSDLPEGRWDLE
                     KFYDPDKSKPGKHYTCHGGFLDKIDEFDPLFFGISPREAAFLDPQQRLMLETSWEAMED
                     GGLDPAKLAGTNTGVFVAGFTLDYQAIQFKNESVESLDTHSATGMMMTMLSNRISYIYD
                     FRGPSLSVDTACSGSLVATHLACGSLLNNECNLAIAGGVSVIATPEYTIAESKGGFLSP
                     DGRCKTFDSSANGYARGEGAGVVVLKRLSDAIEDGDRIYAVISGSGVNQDGHTDGITVP
                     NGQAQENLMKEVYKKAGISPSDITYIEAHGTGTPVGDPIEANAIARVVSTDRPKDKKCI
                     VGSVKTNIAHLEAAAGVAALIKASLIIKHKQIPPHLHFKNPNPKIPFDDLCIRIPQTLE
                     PLPQPALVGINSFGFGGTNAHILLEEATDLQKQGTPEVNVNTGWPYMIPISARSEKALK
                     NYAQKYVDFINGSGESISLYDIGSMMSKKRTHHDYRLAVSASSKEELAENLEAYIKGQA
                     RQGMSAGNVEAGKYNKAVFVYTGMGPIWWAMGRQLLEKDPVFRNMIEKCDKLTRQYAGW
                     SLLEELLADEENSRLDQPQFAQPANFAVQVGLTEVWKSLGIIPHAVVGHSVGEVASTYV
                     AGIYSLEDAMLVSIHRSRAQQKAVNKGTMLAVGLPEKEVVALLDENIKGVSMAAINSPN
                     SVTLSGDPDALEQIQKQLQDKGVFARLLKVNVAYHSYQMEPYEQELLEALKGIKSQPAG
                     IPIYSTVTGKMLTGTECDGHYWYKNVREPVRFEAAMYEMISLNYNLFIEVGPHPVLAAS
                     ISNCLSAKNVEGKKLFSIKRNENEQVSILENLGNLYALGYPIDWNKIYRYQGEFVSLPL
                     YPWQWDKYWMETQESSEFRQGKNKHKFLGRRLKTSSPIWEIELNTTYMTYLSDHKIQGI
                     EVFPGAGYVELGMACARSYFGEGFYTVEDIKFENALFLNQGVSPVVQVVLDPKTAKFEI
                     SSRIPGQDKTWTCNASGTIRKRQNIKITAKDELIQILGNCTKEYGKEVCYKTFYQMGFH
                     YGPYFQGIDKIWKGDNEALGRIEIPKILEIDSSIYGLHPAVLDACFQVTIAAVAPLNED
                     ENNEGQSFLPVGIDRVQLYGRPEPVMLCHTQLVDRKDNNLNANIRLYSEDGNLIAEILG
                     IRTKELGNSGGSDAGRVKDYLYEINWELLKSEEVDTRTAAANSGAWLIFVDHKAAGKEL
                     ANLLEKRGEECFMVYPGEDFGWQYEEREIYINPRSIEDLRSLFDEFSKIKTKLTGIVYM
                     WSLNILEIQEVSNTAIEKACFENLFVLKHLVQATTNLGLNFKLWVITRGAQMINRATPN
                     SAFLQSLVWGLGTVIGYHELPSNWGGLVDLDIEANAGEMEMLLKEVLGNGENQIAFRNG
                     NRLAARIDKLRIDMQHQVPVHLRPDGSYVITGAFGGIGMITAQWMVAKGARHLVLLGRG
                     EFPKRSEWNNVEPGSSLAERIEFVRKLESQGATVYIGSVDVTDEEKLAGFFKDFDKEER
                     PPIRGVVHSAGITDDQFLEVSKDETFYRVLSPKVNGAWNLHRMTEGRPIDFFILFSSVA
                     SVFGSPGQGAYATGNAFLDSLAHYRLSRGLPALSINWGPWSEVGMAARFMERDPEYYIQ
                     KSIESVTVEKGIRAMEHLVGEAVAQSVVLPILSWQTFGEKWFSPMSSPHVLKTLLQDES
                     GQQENINKSKVDVDILEDIISSPIQSRQNIVEMHIKTIVAKVLRYNPEDLSTKQPLTVF
                     GMDSLMATEIKNRMEVAFKTPVSIVELLKGSSIYDLSEQMISKLYESGKISEQGSLNMG
                     KAELERIPKVSEKEHYETSSAQKMMYIINNLEGNNIGYNIPVGILFEGGIERVALGEAL
                     KTLIQRHEAFRTSFEMIDGELVQRIQDEVDFTIEYFESEEDGVEKIIDEFVRPFDLSKA
                     PLIRVGLIEIHASRQILLLDVHHIVSDGTSIIRTFDEIVSILSGESLPAMEVQYKDFAQ
                     WQNGLFSTEVYKKQEEYWLNRFKGEIPILDMPTDYPRPVLQSFEGNRLLFDLDSHLMDK
                     LNVLSSQTGATVYMILLAALNTLMYKYSGQEDIIIGTPIAARTHFDTERILGMFINTLA
                     LRNFPEGNKAFTEFLEEVKESSLEAYENQEYRFDQFVTKLNVKRDSSRNPLFTVMFNIV
                     PSDEHIMEHRGELKYSKYPVESKTSKFDLTFQLIPDGHNIILWMEYATRLFKKETVERL
                     VQHYFNILEEITSNPEKKLSEINMLSQEEKERIIYGFNDTKVEFEHHLTVHHLFEQQTK
                     VRPDNIAVAYEGRRFTYGQINQRANRIARYMLKAGTGREEAVVVMLERGPLFVESVLGI
                     WKAGGAYIPVNPKYPTQRVLDIFKESKAAYVLTLSDYVTQQLSENYKGRIIYLDQCEKE
                     IEAESGENLDLDIDINSLAYVIYTSGSTGVPKGAMIEHLGMINHIHAEIKELCITNNSI
                     ISQNSPQYFDVSVWQFFAALTIGAQIIIYPDEIVKDVARFTNRIIEDGITVLEVVPSYL
                     ALMLEYVENTGNKPEKLHYLLITGETVKSGIVRKWFDLCPNTKVVNAYGPAEAADDITL
                     YTMEAAHEGENIPVGKPIQNMNLYITDKNMNLCPIGVKGEICVSGTGVGRGYLNDPEKT
                     AHVFLEDPFREEKGIRLYKTGDLGRWLPDGNIEFLGRIDHQVKIRGYRIELGEIEAQLL
                     KHSSIKEVVAATREDPQGNKYICAYIVGESELTIPELREYLSKDLPDYMIPSYFVQLEK
                     LPLSANGKVDRNALPAPDGNINTGVDYAAPFGEIEEKLVLIWSQILGVQKIGVNDNFFE
                     LGGDSLKATNLVSRVHKEFDIEFALKEVFMGPTISAIAKSIKNRLNDTVEIEEILSMIE
                     NL"
     aSDomain        20010..21278
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23950_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="4.20E-184"
                     /label="JYU28_RS23950_PKS_KS.1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="426"
                     /protein_start="3"
                     /score="604.3"
                     /tool="antismash"
                     /translation="IAIIGIGCRLPGGIRGPEEFWEALTAGKDMTSDLPEGRWDLEKFY
                     DPDKSKPGKHYTCHGGFLDKIDEFDPLFFGISPREAAFLDPQQRLMLETSWEAMEDGGL
                     DPAKLAGTNTGVFVAGFTLDYQAIQFKNESVESLDTHSATGMMMTMLSNRISYIYDFRG
                     PSLSVDTACSGSLVATHLACGSLLNNECNLAIAGGVSVIATPEYTIAESKGGFLSPDGR
                     CKTFDSSANGYARGEGAGVVVLKRLSDAIEDGDRIYAVISGSGVNQDGHTDGITVPNGQ
                     AQENLMKEVYKKAGISPSDITYIEAHGTGTPVGDPIEANAIARVVSTDRPKDKKCIVGS
                     VKTNIAHLEAAAGVAALIKASLIIKHKQIPPHLHFKNPNPKIPFDDLCIRIPQTLEPLP
                     QPALVGINSFGFGGTNAHILLEEA"
     aSModule        20010..25382
                     /complete
                     /domains="nrpspksdomains_JYU28_RS23950_PKS_KS.1"
                     /domains="nrpspksdomains_JYU28_RS23950_PKS_AT.1"
                     /domains="nrpspksdomains_JYU28_RS23950_PKS_DH2.1"
                     /domains="nrpspksdomains_JYU28_RS23950_PKS_KR.1"
                     /domains="nrpspksdomains_JYU28_RS23950_PP-binding.1"
                     /locus_tags="JYU28_RS23950"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       20496..20543
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0001"
                     /evalue="8.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="181"
                     /protein_start="165"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GPSLSVDTACSGSLVA"
     CDS_motif       20685..20723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0002"
                     /evalue="7.20E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="241"
                     /protein_start="228"
                     /score="12.7"
                     /tool="antismash"
                     /translation="FDSSANGYARGEG"
     CDS_motif       20916..20963
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0003"
                     /evalue="2.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="321"
                     /protein_start="305"
                     /score="13.2"
                     /tool="antismash"
                     /translation="YIEAHGTGTPVGDPIE"
     CDS_motif       21603..21659
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0004"
                     /evalue="2.30E-02"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="553"
                     /protein_start="534"
                     /score="7.8"
                     /tool="antismash"
                     /translation="VFVYTGMGPIWWAMGRQLL"
     aSDomain        21609..22469
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23950_PKS_AT.1"
                     /evalue="1.60E-104"
                     /label="JYU28_RS23950_PKS_AT.1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="823"
                     /protein_start="536"
                     /score="341.4"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VYTGMGPIWWAMGRQLLEKDPVFRNMIEKCDKLTRQYAGWSLLEE
                     LLADEENSRLDQPQFAQPANFAVQVGLTEVWKSLGIIPHAVVGHSVGEVASTYVAGIYS
                     LEDAMLVSIHRSRAQQKAVNKGTMLAVGLPEKEVVALLDENIKGVSMAAINSPNSVTLS
                     GDPDALEQIQKQLQDKGVFARLLKVNVAYHSYQMEPYEQELLEALKGIKSQPAGIPIYS
                     TVTGKMLTGTECDGHYWYKNVREPVRFEAAMYEMISLNYNLFIEVGPHPVLAASISNCL
                     SAKNVE"
     CDS_motif       21783..21842
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0005"
                     /evalue="2.50E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="614"
                     /protein_start="594"
                     /score="11.2"
                     /tool="antismash"
                     /translation="QFAQPANFAVQVGLTEVWKS"
     CDS_motif       21846..21956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0006"
                     /evalue="4.50E-13"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="652"
                     /protein_start="615"
                     /score="41.4"
                     /tool="antismash"
                     /translation="GIIPHAVVGHSVGEVASTYVAGIYSLEDAMLVSIHRS"
     CDS_motif       22311..22355
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0007"
                     /evalue="4.60E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="785"
                     /protein_start="770"
                     /score="12.7"
                     /tool="antismash"
                     /translation="DGHYWYKNVREPVRF"
     aSDomain        22758..23408
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23950_PKS_DH2.1"
                     /evalue="3.60E-33"
                     /label="JYU28_RS23950_PKS_DH2.1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="1136"
                     /protein_start="919"
                     /score="106.8"
                     /tool="antismash"
                     /translation="TYLSDHKIQGIEVFPGAGYVELGMACARSYFGEGFYTVEDIKFEN
                     ALFLNQGVSPVVQVVLDPKTAKFEISSRIPGQDKTWTCNASGTIRKRQNIKITAKDELI
                     QILGNCTKEYGKEVCYKTFYQMGFHYGPYFQGIDKIWKGDNEALGRIEIPKILEIDSSI
                     YGLHPAVLDACFQVTIAAVAPLNEDENNEGQSFLPVGIDRVQLYGRPEPVMLCH"
     CDS_motif       22761..22823
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0008"
                     /evalue="4.80E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="941"
                     /protein_start="920"
                     /score="28.7"
                     /tool="antismash"
                     /translation="YLSDHKIQGIEVFPGAGYVEL"
     CDS_motif       23712..23747
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0009"
                     /evalue="2.00E+01"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="1249"
                     /protein_start="1237"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="MVYPGEDFGWQY"
     aSDomain        24282..24863
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23950_PKS_KR.1"
                     /evalue="1.50E-61"
                     /label="JYU28_RS23950_PKS_KR.1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="1621"
                     /protein_start="1427"
                     /score="199.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GSYVITGAFGGIGMITAQWMVAKGARHLVLLGRGEFPKRSEWNNV
                     EPGSSLAERIEFVRKLESQGATVYIGSVDVTDEEKLAGFFKDFDKEERPPIRGVVHSAG
                     ITDDQFLEVSKDETFYRVLSPKVNGAWNLHRMTEGRPIDFFILFSSVASVFGSPGQGAY
                     ATGNAFLDSLAHYRLSRGLPALSINWGPWSE"
     CDS_motif       24285..24380
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0010"
                     /evalue="2.40E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="1460"
                     /protein_start="1428"
                     /score="49.0"
                     /tool="antismash"
                     /translation="SYVITGAFGGIGMITAQWMVAKGARHLVLLGR"
     CDS_motif       24654..24683
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0011"
                     /evalue="1.80E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="1561"
                     /protein_start="1551"
                     /score="11.7"
                     /tool="antismash"
                     /translation="PKVNGAWNLH"
     CDS_motif       24708..24812
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0012"
                     /evalue="2.00E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="1604"
                     /protein_start="1569"
                     /score="68.6"
                     /tool="antismash"
                     /translation="DFFILFSSVASVFGSPGQGAYATGNAFLDSLAHYR"
     aSDomain        25194..25382
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23950_PP-binding.1"
                     /evalue="1.80E-12"
                     /label="JYU28_RS23950_PP-binding.1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="1794"
                     /protein_start="1731"
                     /score="39.4"
                     /tool="antismash"
                     /translation="IKTIVAKVLRYNPEDLSTKQPLTVFGMDSLMATEIKNRMEVAFKT
                     PVSIVELLKGSSIYDLSE"
     aSDomain        25485..26339
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23950_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.80E-93"
                     /label="JYU28_RS23950_Condensation_LCL.1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2113"
                     /protein_start="1828"
                     /score="303.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVSDG"
                     /tool="antismash"
                     /translation="EHYETSSAQKMMYIINNLEGNNIGYNIPVGILFEGGIERVALGEA
                     LKTLIQRHEAFRTSFEMIDGELVQRIQDEVDFTIEYFESEEDGVEKIIDEFVRPFDLSK
                     APLIRVGLIEIHASRQILLLDVHHIVSDGTSIIRTFDEIVSILSGESLPAMEVQYKDFA
                     QWQNGLFSTEVYKKQEEYWLNRFKGEIPILDMPTDYPRPVLQSFEGNRLLFDLDSHLMD
                     KLNVLSSQTGATVYMILLAALNTLMYKYSGQEDIIIGTPIAARTHFDTERILGMFINTL
                     ALRN"
     aSModule        25485..28583
                     /complete
                     /domains="nrpspksdomains_JYU28_RS23950_Condensation_LCL.1"
                     /domains="nrpspksdomains_JYU28_RS23950_AMP-binding.1"
                     /domains="nrpspksdomains_JYU28_RS23950_PCP.1"
                     /locus_tags="JYU28_RS23950"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       25557..25664
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0013"
                     /evalue="3.40E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="1888"
                     /protein_start="1852"
                     /score="35.5"
                     /tool="antismash"
                     /translation="YNIPVGILFEGGIERVALGEALKTLIQRHEAFRTSF"
     CDS_motif       25956..25988
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0014"
                     /evalue="2.80E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="1996"
                     /protein_start="1985"
                     /score="13.6"
                     /tool="antismash"
                     /translation="QYKDFAQWQNG"
     CDS_motif       26247..26336
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0015"
                     /evalue="1.40E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2112"
                     /protein_start="2082"
                     /score="40.0"
                     /tool="antismash"
                     /translation="DIIIGTPIAARTHFDTERILGMFINTLALR"
     CDS_motif       26385..26501
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0016"
                     /evalue="4.90E-14"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2167"
                     /protein_start="2128"
                     /score="44.6"
                     /tool="antismash"
                     /translation="KESSLEAYENQEYRFDQFVTKLNVKRDSSRNPLFTVMFN"
     aSDomain        26844..28058
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23950_AMP-binding.1"
                     /evalue="4.60E-100"
                     /label="JYU28_RS23950_AMP-binding.1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2686"
                     /protein_start="2281"
                     /score="327.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEQQTKVRPDNIAVAYEGRRFTYGQINQRANRIARYMLKAGTGRE
                     EAVVVMLERGPLFVESVLGIWKAGGAYIPVNPKYPTQRVLDIFKESKAAYVLTLSDYVT
                     QQLSENYKGRIIYLDQCEKEIEAESGENLDLDIDINSLAYVIYTSGSTGVPKGAMIEHL
                     GMINHIHAEIKELCITNNSIISQNSPQYFDVSVWQFFAALTIGAQIIIYPDEIVKDVAR
                     FTNRIIEDGITVLEVVPSYLALMLEYVENTGNKPEKLHYLLITGETVKSGIVRKWFDLC
                     PNTKVVNAYGPAEAADDITLYTMEAAHEGENIPVGKPIQNMNLYITDKNMNLCPIGVKG
                     EICVSGTGVGRGYLNDPEKTAHVFLEDPFREEKGIRLYKTGDLGRWLPDGNIEFLGRID
                     HQVKIR"
     CDS_motif       27030..27068
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0017"
                     /evalue="6.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2356"
                     /protein_start="2343"
                     /score="13.2"
                     /tool="antismash"
                     /translation="LGIWKAGGAYIPV"
     CDS_motif       27270..27329
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0018"
                     /evalue="5.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2443"
                     /protein_start="2423"
                     /score="31.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGVPKGAMIEH"
     CDS_motif       27411..27437
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0019"
                     /evalue="9.90E+00"
                     /label="C4_LCL_164-176"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2479"
                     /protein_start="2470"
                     /score="-0.4"
                     /tool="antismash"
                     /translation="QYFDVSVWQ"
     CDS_motif       27846..27935
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0020"
                     /evalue="2.10E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2645"
                     /protein_start="2615"
                     /score="45.6"
                     /tool="antismash"
                     /translation="PIGVKGEICVSGTGVGRGYLNDPEKTAHVF"
     CDS_motif       28023..28088
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23950_0021"
                     /evalue="2.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2696"
                     /protein_start="2674"
                     /score="38.7"
                     /tool="antismash"
                     /translation="FLGRIDHQVKIRGYRIELGEIE"
     aSDomain        28380..28583
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23950_PCP.1"
                     /evalue="2.00E-24"
                     /label="JYU28_RS23950_PCP.1"
                     /locus_tag="JYU28_RS23950"
                     /protein_end="2861"
                     /protein_start="2793"
                     /score="77.6"
                     /tool="antismash"
                     /translation="EEKLVLIWSQILGVQKIGVNDNFFELGGDSLKATNLVSRVHKEFD
                     IEFALKEVFMGPTISAIAKSIKN"
     gene            28683..>33511
                     /locus_tag="JYU28_RS23955"
                     /old_locus_tag="JYU28_23995"
     CDS             28683..>33511
                     /NRPS_PKS="Domain: Condensation_LCL (48-332). E-value:
                     2.5e-110. Score: 360.1. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23955_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (501-900). E-value:
                     2.8e-124. Score: 406.8. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23955_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1007-1076). E-value: 1.6e-24.
                     Score: 77.9. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23955_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1091-1375). E-value:
                     2e-102. Score: 334.2. Matches aSDomain:
                     nrpspksdomains_JYU28_RS23955_Condensation_LCL.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="JYU28_RS23955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_23995"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_208332721.1"
                     /sec_met_domain="Condensation (E-value: 1.7e-91, bitscore:
                     303.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-127, bitscore:
                     422.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.8e-14, bitscore:
                     49.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNLMKRIESLSPEKRKLFETMLKEKGKDVSKYTPNAFSGIPSAR
                     EQEFYPMSSAQKRLYILNELEGAGTAYNMPGVVLLEGNIDAVRFEQAFKELVKRHEALR
                     TSFHMVEGEPVQKVHDYVDFSITYLELDEEKAAEIVKEFITPFDLSQVPLLRVGLVKTN
                     EDRRVMMFDMHHIVSDGISVNILMSEFLDLYQGKTLLPLRIQYKDFSVWQKEMFAGDSI
                     KKQEEYWLQTFKGDIPVLDMPTDYPRPAVQSFEGDAVSFEINPELSVKLNKLATDNGAT
                     LYMVLMAAYNVLLSRYTGQEDIIVGSPVAGRPHADLQGIIGMFINTLAIRNYPEGEKTF
                     VQFLQEVRENAFLAFENQNYQFEELVEKLNLMRDMSRNPLFDTMFALRTSNKTEFAASG
                     INFKQYNNWLEGRKAKFDLMLEVVEGQEGITFNLEYCTRLFKKETIKRFGTHYISVLEE
                     ITACPEKRLWEIDVLLQEEKQQILYTFNATEAQYPKNKTIHQLFEEQAEKNPDHVAVVF
                     EGKKLTYSELNKKSNGLAHVLRAKGVKPDSIVGILAERSLEMIVAILGVLKAGGAYLPM
                     DPDYPEERISHMLEDSRAVILLTQSHFIDKYTSIGTVINLEDEQEYSDEQYNLSEVNKP
                     SDLAYLIYTSGSTGKPKGAMIEHRNIVRLLFNSKMQFDFNENDVWTMFHSMSFDFSVWE
                     MYGALLYGGRLVVVPKMTARSNVEYLRLLRNEKVTVLNQTPSAFYNIANEEVSYEEKEL
                     KIRYVIFGGEALKPALLNEWRKKYPQTRLINMYGITETTVHVTYKEIEEEEIRSNVSSI
                     GRPIPTLTTYVMDKNMKVVPIGVAGELCVGGDGVCRGYLGRPELTKEKFVQNPYKPEER
                     LYRSGDLVRLLSDGEMEYLGRIDHQVKIRGFRIELGEIEAQLLKHPSIEESLVIAKEDH
                     QGSKYLCAYIAGENELTISELREHLLKELPEYMVPSYFVQLEKMPLTANGKIDRKALPE
                     PEGNINTGIEYEAPIGEFEEKLALIWQDILGIKKIGRNDNFFMLGGHSLKATSLVARIH
                     KEFNIDMPLKEIFKAPIIAEIARYMKEAKESIYQSIQTAKEMEYYPMSSAQRRLYILNQ
                     FEGAGTAYNMPGSLLVEGSIDLELFQKTFQQLINRHETLRTSFHFIEGEPVQKINDPVG
                     FSVVYLESDEEKVGEIVKEFIKPFDLGIAPLLRVGLVKTGKDKHVMMFDMHHIISDGTS
                     MDILVHEFMDMYGGNNPSSLRIQYKDYSVWQKELFAGDKIKKQEEYWLQEFNGEIPVLN
                     MPVDYQRPAVQSFDGGFIRFEAGSELTGKLIKLARDNGATLYMTLLASYNILLSKYTGQ
                     EDIIVGSPIAGRPHTDLQDIIGMFVNTLAMRNYPQGEKTFAEFLKEVRENSIRAYENQD
                     YQFEELVEKLNVKRDMSRNPLFDTMFVLQNTGSSELKIDRLKFIPYTNEFRISKFDLTL
                     NARETQEGIAFDLEYATRLFKKETVERFAAHYLNVLEEITVYPGKRLSEIDMLSQEEKQ
                     KILYDFNDTKVRYPKDKTIHQLFEEQVEKTPNNIAVVFEDKQLTYKEVNEKANQLARKL
                     REKGIKPDSVVGIMVERSPEMIIGIMAVLKA"
     aSDomain        28827..29678
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23955_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.50E-110"
                     /label="JYU28_RS23955_Condensation_LCL.1"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="332"
                     /protein_start="48"
                     /score="360.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVSDG"
                     /tool="antismash"
                     /translation="FYPMSSAQKRLYILNELEGAGTAYNMPGVVLLEGNIDAVRFEQAF
                     KELVKRHEALRTSFHMVEGEPVQKVHDYVDFSITYLELDEEKAAEIVKEFITPFDLSQV
                     PLLRVGLVKTNEDRRVMMFDMHHIVSDGISVNILMSEFLDLYQGKTLLPLRIQYKDFSV
                     WQKEMFAGDSIKKQEEYWLQTFKGDIPVLDMPTDYPRPAVQSFEGDAVSFEINPELSVK
                     LNKLATDNGATLYMVLMAAYNVLLSRYTGQEDIIVGSPVAGRPHADLQGIIGMFINTLA
                     IRN"
     aSModule        28827..31910
                     /complete
                     /domains="nrpspksdomains_JYU28_RS23955_Condensation_LCL.1"
                     /domains="nrpspksdomains_JYU28_RS23955_AMP-binding.1"
                     /domains="nrpspksdomains_JYU28_RS23955_PCP.1"
                     /locus_tags="JYU28_RS23955"
                     /monomer_pairings="Thr -> Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       28890..29006
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0001"
                     /evalue="3.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="108"
                     /protein_start="69"
                     /score="58.1"
                     /tool="antismash"
                     /translation="TAYNMPGVVLLEGNIDAVRFEQAFKELVKRHEALRTSFH"
     CDS_motif       29199..29264
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0002"
                     /evalue="2.80E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="194"
                     /protein_start="172"
                     /score="29.5"
                     /tool="antismash"
                     /translation="MHHIVSDGISVNILMSEFLDLY"
     CDS_motif       29295..29330
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0003"
                     /evalue="1.00E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="216"
                     /protein_start="204"
                     /score="14.9"
                     /tool="antismash"
                     /translation="QYKDFSVWQKEM"
     CDS_motif       29586..29675
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0004"
                     /evalue="4.90E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="331"
                     /protein_start="301"
                     /score="51.0"
                     /tool="antismash"
                     /translation="DIIVGSPVAGRPHADLQGIIGMFINTLAIR"
     CDS_motif       29733..29843
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0005"
                     /evalue="3.80E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="387"
                     /protein_start="350"
                     /score="48.2"
                     /tool="antismash"
                     /translation="AFLAFENQNYQFEELVEKLNLMRDMSRNPLFDTMFAL"
     aSDomain        30186..31382
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23955_AMP-binding.1"
                     /evalue="2.80E-124"
                     /label="JYU28_RS23955_AMP-binding.1"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="900"
                     /protein_start="501"
                     /score="406.8"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEEQAEKNPDHVAVVFEGKKLTYSELNKKSNGLAHVLRAKGVKPD
                     SIVGILAERSLEMIVAILGVLKAGGAYLPMDPDYPEERISHMLEDSRAVILLTQSHFID
                     KYTSIGTVINLEDEQEYSDEQYNLSEVNKPSDLAYLIYTSGSTGKPKGAMIEHRNIVRL
                     LFNSKMQFDFNENDVWTMFHSMSFDFSVWEMYGALLYGGRLVVVPKMTARSNVEYLRLL
                     RNEKVTVLNQTPSAFYNIANEEVSYEEKELKIRYVIFGGEALKPALLNEWRKKYPQTRL
                     INMYGITETTVHVTYKEIEEEEIRSNVSSIGRPIPTLTTYVMDKNMKVVPIGVAGELCV
                     GGDGVCRGYLGRPELTKEKFVQNPYKPEERLYRSGDLVRLLSDGEMEYLGRIDHQVKIR
                     "
     CDS_motif       30372..30413
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0006"
                     /evalue="5.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="577"
                     /protein_start="563"
                     /score="16.5"
                     /tool="antismash"
                     /translation="LGVLKAGGAYLPMD"
     CDS_motif       30597..30656
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0007"
                     /evalue="3.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="658"
                     /protein_start="638"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGKPKGAMIEH"
     CDS_motif       31176..31265
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0008"
                     /evalue="6.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="861"
                     /protein_start="831"
                     /score="53.6"
                     /tool="antismash"
                     /translation="PIGVAGELCVGGDGVCRGYLGRPELTKEKF"
     CDS_motif       31347..31412
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0009"
                     /evalue="9.00E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="910"
                     /protein_start="888"
                     /score="40.0"
                     /tool="antismash"
                     /translation="YLGRIDHQVKIRGFRIELGEIE"
     aSDomain        31704..31910
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23955_PCP.1"
                     /evalue="1.60E-24"
                     /label="JYU28_RS23955_PCP.1"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="1076"
                     /protein_start="1007"
                     /score="77.9"
                     /tool="antismash"
                     /translation="EEKLALIWQDILGIKKIGRNDNFFMLGGHSLKATSLVARIHKEFN
                     IDMPLKEIFKAPIIAEIARYMKEA"
     aSDomain        31956..32807
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JYU28_RS23955_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.00E-102"
                     /label="JYU28_RS23955_Condensation_LCL.2"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="1375"
                     /protein_start="1091"
                     /score="334.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="YYPMSSAQRRLYILNQFEGAGTAYNMPGSLLVEGSIDLELFQKTF
                     QQLINRHETLRTSFHFIEGEPVQKINDPVGFSVVYLESDEEKVGEIVKEFIKPFDLGIA
                     PLLRVGLVKTGKDKHVMMFDMHHIISDGTSMDILVHEFMDMYGGNNPSSLRIQYKDYSV
                     WQKELFAGDKIKKQEEYWLQEFNGEIPVLNMPVDYQRPAVQSFDGGFIRFEAGSELTGK
                     LIKLARDNGATLYMTLLASYNILLSKYTGQEDIIVGSPIAGRPHTDLQDIIGMFVNTLA
                     MRN"
     CDS_motif       32019..32135
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0010"
                     /evalue="1.40E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="1151"
                     /protein_start="1112"
                     /score="52.8"
                     /tool="antismash"
                     /translation="TAYNMPGSLLVEGSIDLELFQKTFQQLINRHETLRTSFH"
     CDS_motif       32328..32393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0011"
                     /evalue="4.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="1237"
                     /protein_start="1215"
                     /score="28.8"
                     /tool="antismash"
                     /translation="MHHIISDGTSMDILVHEFMDMY"
     CDS_motif       32424..32459
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0012"
                     /evalue="8.70E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="1259"
                     /protein_start="1247"
                     /score="15.1"
                     /tool="antismash"
                     /translation="QYKDYSVWQKEL"
     CDS_motif       32715..32804
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0013"
                     /evalue="7.60E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="1374"
                     /protein_start="1344"
                     /score="50.4"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHTDLQDIIGMFVNTLAMR"
     CDS_motif       32853..32972
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JYU28_RS23955_0014"
                     /evalue="1.30E-18"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="JYU28_RS23955"
                     /protein_end="1430"
                     /protein_start="1390"
                     /score="59.3"
                     /tool="antismash"
                     /translation="RENSIRAYENQDYQFEELVEKLNVKRDMSRNPLFDTMFVL"
ORIGIN
        1 ttccttacct tggacccatc tgggagctcc ctgtgcttct tccccttggc agtgacaagc
       61 agggagtgaa caaacatctg ctgcttgtca gccctgtggg gaagggagcg gatgtcgagg
      121 tgttctattg gatcggacaa cttgacaagc aaaatctttc gttcatcccc gatcaagaag
      181 agcctcaatt gattgatgtc ggggatttcc attttaccgg accgagcgga atggttgatc
      241 cgaagaccgg cagaaatatc gtctttacga tagcccaagg cgaccggacc tccgagatgg
      301 aatataagtc gggttgggct cataacggag gcttgccgtt aagcgtgtat ttgagggatg
      361 acggacgtct gggaatagag ccgattcagg agcttcaatc gctgcgtggc cctaagcggc
      421 tatcgcttcg ggaccagtca ttggctgaaa ctaatgtgca gcttaggaat gttcatggtg
      481 acatgcttga gattcaattg gaattggagc ccggcagcgc caaaaaattc ggagtcaagg
      541 tccgttgtac gccggacgga gaggaagaaa ctctgctgta ttatgattgg aatcaagcgt
      601 tgctcatggt cgaccgctcg aaaacgaccc tgcatcctgg agaaaagtgc ggagggattc
      661 aaggcggtaa gttggagctg cttggggaga atctgaagct tcacatttat ttggaccgct
      721 ccatggtcga agcttatgca agcggattga aaagcctgac aacccgggta tatccgagcc
      781 gtatggatgc tttgggactc gagatttggg gagatggaga accgtttgtt aaatccttgg
      841 atatatggga tatgcagtcc gtttggtaag acggttgttt aggcgctcct tacgaatggg
      901 gtatgcacaa atgatcaaga aactttgcat tcctccgttt ggaaattttt cattcatatt
      961 ctcccttctt catgactatt catctttgta caaggagagc atttcgaaat gaggtatcga
     1021 tgttcgcaag tataacaagt ttcgaaggag gctcgagaat gaggaaagtc aaaagaggaa
     1081 aatgttggat atcgggaatg gttatatggg ctatggtgct ccagcttgtt gttccgggaa
     1141 tctctgtcgc gtccgaaaat agaactgttg ctggagaaac gctcattcct aagaatgatg
     1201 tgaaatcatc ggttacggat gcgatttatc aaatcaagaa tattcctaag aatgacatgg
     1261 gattgtcagt tacagattca gtctatcaaa tccggaatcc tggatttgaa acaggagatt
     1321 tgacgggatg gaccgttatc aaaggcgatg cgttcggtcc gaatagcgta accgacgaaa
     1381 cgacttggtg ggcagaaaaa ataccgtata accaggaagg agcttatcat ttaaacggct
     1441 ggaagtatga cgaatctgcg acaggtgtac ttcgttccag cactttcgag ctgggcggaa
     1501 gcggctggat cagcttcaag cttggcggtg caaagaaccc agacaaggta tttataaata
     1561 ttgtggaagt cgatacggga caagttattg cccgatacgg aaatagcgca ttcgccgacg
     1621 ttggcttccc ggatcctgcg cagggcatgc ggcttgccaa tatggtgcaa tacaaggcgg
     1681 atctttccac acaattgggc aagaaactgt atgtggaggt cgtcgataat gcaacctcgg
     1741 attggggagt catttttgcg gacgcattct ccatgtacca tgagtcggag ccagctgaag
     1801 gaattgttgc gacggatatc aagccggatt tcaagcgcta tgaaatcgat aatccaagct
     1861 ttgaaaccgg aaatctcgat ggctggacgg ttgaggaaga tgcttttgaa gtgactgatg
     1921 aagctcatgc gagcaaagaa gggaactttt atgccaaatc ctccctgcaa ggaaagggct
     1981 ccatcacttc taatactttc acgcttcagg gaaccggaac aattaatttt actgttttgg
     2041 atatcctcaa accggaaaat gcatatgttg cacttttcga tgcgaacagc aacacattgc
     2101 ttatgaaaac cgggaatgtc agcgcgaacg agaaaatctt atggaaagtg caagaacact
     2161 acaacaagaa gctctatgta aaggttgtcg atcattccaa tgaagccagc attgccgttg
     2221 atagtttcca agcaagtggt agggggacta ttttctactt aaaccttgat gaaggcgcag
     2281 gaaagaaagc gttggagaaa gtacacgatc ttaagcacga tgtgaactat gtatttaaca
     2341 acgccaggta tatggcgtcg aaggatccga gatggactcc gcgcggaata aaaggcggcg
     2401 ccttattgtt cgatggatac tcgaattata ttgaggtcaa tgcaaacgat actgtgccta
     2461 taagcgacgc gttaaccatc gaagcttggg ttgcaccgcg tagctatgag tggggagacg
     2521 gaaacaagct gtctgcgatc gtaaaccaat ccgaccagga taaagcggaa ggcttttctc
     2581 ttggtatgta tcggcacggt acatggtcga tgcaagtagg cataagcggt cagtggattc
     2641 aggtatgggt aaaggatcac ccgttggaaa aatacaagtg gaattatgtg gccgctactt
     2701 tcagtaaaga agatggaaaa attaagttat atctaaacgg tgaggaagtg gcttcccaag
     2761 taacccccct caacgttccg atcacaccat ctaccgaaag cctgatcatc gggaaaaata
     2821 ataaacctgt agagttagca ggggtgttct ccttcaatat gttcagcgga ctcctagatg
     2881 aagtgaagct gcataataaa gcccttacga accaggagat acttgctgga tatgagagcg
     2941 tgaaggcgct tcatggaggt gcaattccga aaattccaaa tgcggacatt gatgaggatc
     3001 caagtgtgtt tggcggagat cagcaccgac cccagtacca cgcgatgcct ccgcaaaact
     3061 ggatgaatga agcacatgca ccgatttact ataacggcaa ataccattta ttttatcaac
     3121 ataacccgca aggtccattc tggcatcaaa tccactgggg gcattgggtg agtgacgata
     3181 tggtgaactg ggaaaatgta agacctgctc ttgcgcccga agcgggcacc ctagatccgg
     3241 acggcacgtg gtcaggcagt gcagcgtatg atcgaaacgg caatcctgtt ctgttctata
     3301 ccgctggcaa cgactccttg tcgccgaacc aaagaacagg gttggcaact ccggcggatt
     3361 tgtccgatcc ctatttggaa aaatgggtga aatatcctaa accggtaacg gagcagaacg
     3421 gaaaaggcat ccacaacgag ttccgcgatc cgtttgtatg gtacgacaaa gaggtggaca
     3481 agtggtatca gttagtgaca tctggtcttc cagacttcag cagcggcaca gctttggtgt
     3541 atgtatccga tgatatgtac aattgggaat ataaggggcc gctatacgtt agtgacagaa
     3601 gccgttatcc agagttgggt acggtatggg agctaccagt gttattgccg ttaggcacgg
     3661 atagtacggg caagcaaaaa tatattttca tgattaatcc ccatgaaaag ccggagcatg
     3721 ttcctccagc gaacgatgtg caaagagatg ttgaggtctt ttactggatc gggacttggg
     3781 accgggataa ctttaaattt attcctgatc aggaggcacc ctccaaaatg gatgtaggtg
     3841 acggctattt aaccgcagag agcggtctgg tcacacctga cggaagaacg gtcgtattct
     3901 ccatggtgca aaatgtaaga acaccgcaag ccgaatatca atccggatgg gctcataatt
     3961 tatctttgcc ggtttcccta agcctcgata accatgataa attgcatatc gaaccgatta
     4021 aagaactgca gagccttcga gggaaaaaat gggttgattt ttcggacaaa aatttggaaa
     4081 gcgccaatca attgatccaa aatgtcaaag gcgacatgct agagattgtg atggagattg
     4141 atccgcgtga ggcccagaaa ttcggtctca aggtacgccg ctcggaaaaa ggccaagaag
     4201 agacgctcat ttactacgac aagaagaacg ggacgtttaa tgtggatcga accaagagca
     4261 gcattgatcc agatgtgcgt gtggacggca ttcaaggagg atatgtagat cttaaaggag
     4321 agaacttgaa actccatatc tttctcgatc gctcggtcat tgaagccttt gcaaattaca
     4381 agaagaagct gacaacacgt gtctatgtag gcagatacga ctccttaggc ttacagatct
     4441 gggccgatgg cgatatcaat atcaaatcca tgcaagtatg ggatatgaat gccttaacgg
     4501 gtaaaccggc tgctccggtc tatgtacccg ataagtggga taattctgtg tataaggata
     4561 ttacagagct gcctaaccat gattttgcta cgggagactt aacaggatgg atgacggaag
     4621 gagacgcctt ccagaatgtc catgtgacca atacccagtt cttctgggac aacatttact
     4681 tcaacccgtc gcataaaatt ccgggcggct accatttgtg gggcttcaac gagcaagccg
     4741 gcggcgatag cttaaccgga gcactaagat ctcaaaattt cgtccttggt gggaacggta
     4801 agatcaactt ccttatcagc ggcggccggg atatagatcg tctgtatgtt gcgctggttc
     4861 gggcgtcgga cggcaaagag ttatttaaag agacagcgac caattatgaa gaatatcaac
     4921 gtaagatttg ggatgcgtcg gattatatcg gggaggagct ttatataaag gtggttgacc
     4981 actccaaagg cgggtttgga catattaacg tcgatgattt taatgtacct gttcaggtaa
     5041 agaagaaaac taacaactga ctcttgttaa tacagaatac ccgtgagtcc tgtagtcact
     5101 ccaagcaaat cgaatagtca aatagcttat cattcgaaat ggcatcggta ttgtatctga
     5161 ttctggaatt gagcttttga taaatgggaa gtaaataatg taaatctcga aaccccttat
     5221 cttatctatg gatagggggt gaattattgt tgtcagaatg caacgtattg tgtagaatta
     5281 aagaaaatta tggaaacata attgaggtgg gggtggtccc tctatactca acttatacag
     5341 aggaatgaat aaaaatgctt gggagagggg gggagtgtgt gtataaagag cttctgagta
     5401 tagcacagct aatgggggaa acaatgcgat tggttgggta tgcccgatac tacaaatccc
     5461 ttaacattga tggtttacat tacatacatc aagtagaagg tacccaagtg atcgctattg
     5521 ttaaaccaaa tcatagtact catcatgaag ctacaacatt tttaatgaat ctattattaa
     5581 cggaaaagct aaaaatgaat acggttacag ggcatgccca gaatctgaaa aagttcttgg
     5641 attacatgat gttctggagg ctagaggaag attttgaaca tatccataat atcgaagtaa
     5701 aagcaggtgg accgtatcct attgaagtaa tattactggg atttgcggat taccttcgat
     5761 gtattccaaa aggttacaag ccatttgaag atttaaaggt ggcgactcac gggattcatt
     5821 ggtctatgtt aaagaatatc ccccttaaca aacatgcaat ggcagaaggg aagctatcaa
     5881 ccgtaattcg aagcagtcat aacgatttaa agaaaaccaa ctggtgtgag tacccgtctg
     5941 gtgcacttgc tccgatcatc tatactgcat gtgcatatct gaagttcttg cgtgatagaa
     6001 caacaagatt taaatacctg ccattagagc aggttccgag aaaagaaata agagataatc
     6061 attcattaat agcgggtact gcgggtagta gggtgcggat agtgtttgat gtggaaaata
     6121 ttgctcgaga ttccggtact gcaggacctg gaggagggaa gagcaggcaa gcctctccca
     6181 ttaaccacga caaggtcttt agtgagaccg aagcagacat gttctttgaa ttgatcgatc
     6241 cgtatgaaaa tgctttggat cttcttctct ttgcgatatt gcgttacttt ggattacgcc
     6301 ctggtgaagc agctgagatt cgaattgagc cgtcaacaat tccttccaac ttaaacgtgt
     6361 atcatacagc aagagaggaa ttaaccgagt ctctttccgg gaacttgcag tttgtaaaag
     6421 aacgcgggtt gcgggggaat tgggtcattg atacgggatg gaaaacgaag gcttcctgca
     6481 gggacgtggc gttgataact cacaaaacaa ttgatccatt tagcaggaaa aatatccgat
     6541 ttccaacaca agaggagttc actgatcttc tgtattgggc acttcttcag cggcgggaac
     6601 ttttgtctta ttacacaagt gaagatcatg gctatctatt tgtatcagag tcaaacaatt
     6661 caaaagggaa gccattaagt aagaaaggcg tttacagtaa gtataataat ttggctgatg
     6721 acttatttca acgaactggg ggaagcgtag acctacgttc ctactatcca cacaccttcc
     6781 gacacttatt cgcgacatca cttctcctaa gatatcgcag accaatcgaa gagatcagca
     6841 agtggttggg gcattcttct gtcgtgatta cgcgcgatac atatattcat tggatacctg
     6901 agtcaaataa tgacacagaa aaaggtaaag tagatcattt agggagggta tttatgcgac
     6961 aggcggagat ctcagaggga atccacgcgc atgaggagga ctcggaatga cactagaatg
     7021 gactccatta tcggaatttc gcaaattttt aaaaaacacg ctgcgtttga atcatgtgaa
     7081 tcaagtattt tcttctataa aaaatcccgt ccttcaatta tttactacat ttccggcccc
     7141 ggataactgg ttagctgtac cgcctgaaga gagaccaacc tttcggcatc gcgacagtcg
     7201 agacctatgg tatgtcattt tctgggcttg gcatacaggt ttttgcaagg gaaatgatgt
     7261 agtagcacaa tatcgtcgaa acgacttggt ttgttacctg tcaaccagag gtcgtgttaa
     7321 tctgtcggat ttccccgtca aaatgggcct cctcaaaaat tcagaagcag aacacatccg
     7381 caaaaaagac tcaaaccgta taggtttgtt caacaaacta tctatacacc ttctaggtgt
     7441 tatgaaaccg ctgggcgatt tcacggaaga agatatagcg ttagcggatg taatgcgtcc
     7501 gaacgacaaa cgttataacg ccaagtgttt aaaggacatt ctttttgagc ttggatattc
     7561 ggatgaacca ggaagacgta ggcaaagaat actgtttgac gattgctgtg agcatccaaa
     7621 gtggggggga tatcgcacgt gagtttcgcg agcatttaaa acgaagtaat tcgctagact
     7681 attatattcg taaagcgggc agtgctttgc ataaattttt caaatggctt gaccagcacg
     7741 gggagtcgga tgcttcatct ctcgagtatg aagattttct cgatttgttt gattacattt
     7801 caaagaataa cgatggagag gagttttcag ctaagtatac cgggaacaat cttctacaca
     7861 taaagttatt ctttgattgg gggaaaggtt ctcatacatt ttttccaaca tacgttgact
     7921 ggcccagtga tttatattct ggaattcatc gtgaggccca agaagaaaca tattccggtg
     7981 atggcctcgc ttttgatgac ccaaacttcc cgatgctcat gaaggaagca attgaaaatt
     8041 atcatcccga agatgatgtt gaagttttat gtcgcgcttt ttggttaatt attgcctcat
     8101 caccggtgcg taaaacgtat ctgctcaatc ttcaggctga agaatgtatg ctgccattgc
     8161 ctaatgctcc atcagcggta ggattataca gcccatattc aggtattgag aaagctaaac
     8221 atcgtaacgg ccaatttcct ataattgatt ctgcaggtct tagagcggtc gaatttttac
     8281 agaaaagatc gagcgataaa gccttccgac cgatacggaa cgaaagagcg gatgcatcgt
     8341 atgtgcatct ttttcaattg gagaaatatc cctggatttt gaatgaaaga caaatatata
     8401 ggttttttga caagatagca gaatttattg gacatggaga taaaaaaggg aaggctcatg
     8461 gttacagaca ctatctcata actcacattg caatcgaaac cgggaacagt gagttagcac
     8521 gacttgctgc aggtcatgaa aatcaaacca tgctgaatcg atacttacga agtaatctct
     8581 cccgtcaagc attgttattt gctactatta agaaatatca ggatggtgag attgcgggac
     8641 ggtttatttg gcgaatcttc gaagcacttg ccagcgaaca aactgagcct gacgaattga
     8701 taaaagcttt gggatctgaa gagctatctt tagatgaatt ctttgcaaaa ttcgggcttc
     8761 cagctcctac aggtgtagga agatgtttaa tacagggggc ttgccttttt gaggcaaagt
     8821 gtttttcctg tcatcatttc gccatacgaa aaagtgaagc agcacaggca tttcatactt
     8881 tggccagatt aaccaaggac atgtggaaca tgatgcgagg cagtcgggat tttacaacca
     8941 aaaacgccaa ggcggccgga ttagctacgc aaatagcgtt gcttggggac atgattcggc
     9001 atttcggcta tagtgacgaa cagattcaaa tagaggttat cagtcgacta gtctgagctt
     9061 agattggaaa gaggtgaaat cgtgtcgcaa atattagctt ggcaatccct gagatttgga
     9121 cccattactg taaggcgaaa gggacaattc gagagtagag agcatctgac aagatcggag
     9181 tatgaacaat acagatcggc agagacttgg ggacgggttg aacctatttt atcaagctcc
     9241 ttaacggatt tggtacaacc cacaatattt ttcaagttac ccggcaccca aagagattac
     9301 gtattactgc ttgccttttt acaacggatc agtttgcctt tagagatcgt atttccaacc
     9361 aagaccgaat tcaataaatt tccttttccc gagttaccga attttgagta ctttgatgcg
     9421 ctttacgata aatactatcc ggtattgtat ccgatggata gcgaaaaaca actacaaaag
     9481 gcaaagaaaa ggattccttt gcttcgaact gtagtttgct tatggttcgc aggttacgcc
     9541 cttaaggaag ggttagaggg taatcatatt attacttcct ctgtattagc aaaagcaagt
     9601 aagatcgcta aatatcatag aagtagttta accctcctag gtaagatgtt agctaaagaa
     9661 acagattcct tgattgaaaa taaaccggtc ataccttgcg atgaagcgga aagaagtgtc
     9721 tggatagccg cgggaatata tccaacccaa acgccgtttg aggagagtct ctataccttt
     9781 gcattttctt acttgaggca acgtgtgaat gattcaataa ctgatgatta ttacgacgat
     9841 gaaggaaatt tacttttcag atacggtaaa aaaactatca gcataaatta ttggaaagcg
     9901 atagtcaagt acatccggta ttttgcaatc aaatgtcgat caaaaggtct tactgacata
     9961 agcgagaatt caatatcaga agtatacaca gagatttttg gccagatgaa gggacaagaa
    10021 gataagacgt ttttccgagt ggcgcttcga cattggctta ggtggcttat aagaactaca
    10081 aatgcttcat acaacataga acggattatg ccaagaccta gacgtgttat gtcaaaagat
    10141 catggacgag tatttagtat gtccaaagct tatattcttg tgcagacctt aatgaacgat
    10201 caaactcctt taattaacga gaacattctg atggactttc gtcataggcg ggcttgcctg
    10261 ttgatgttat caactgcagc aaggcctcat gaaatagtta atttgcttca gaatgcttta
    10321 tttatagatt cgcaggataa ttcctggatt cgttttcaca aaaccaagac cattcgcaat
    10381 caacccgatc gaaacggcta tgaatgggtt catcacgctc tagtgaagag cgatgctgca
    10441 agatggttta acgaattgat tcattttgcc ccatcagaac ctatattttt tccaagagag
    10501 tggggtgggg atggccttac ggaacttcgt ttactggctt caaaacataa tgatggccct
    10561 atacgaacta gcggactgta taatttttta actcgcattc aatcgaagtt atggcctgaa
    10621 cttaggaagc catatttcac accccataat ctaagagcgc tccatcttac ttatcggcgt
    10681 atcttaggag acaatgatga gctactagag aggcaggccg gacatagtca tccttcctca
    10741 aaaaagcctt atacggaaac aatgcctgca gaagaagttg caaagtttgg tcatctactt
    10801 caaaaaggcg tttggagaaa gaaaccggaa ggggaggatg ctgataagac agaaggggct
    10861 ggaatttcgt ctactgaata tgtagccatt gatgagataa ccgaaatttc atctaagttt
    10921 gaggtcacgc ctcaaaagct agatgaagca tataaattaa cccagaaaat tatagaggaa
    10981 tcaccacgtt tccaaggtaa atttattgat ttggaagatg agttacacga ggttaacgta
    11041 ggtggttata cgcataattg taatgcacat gtcttgctaa actgtggtca tacacccggg
    11101 cattgtagag catgtgatga ttatagtcct gatgagggta cagaagatgc gcacaaggcc
    11161 gacatatttc gtgaaatgtt gcattattac tattgtctcg atgcagagaa aaatttcaag
    11221 tccacaggac aacgaaaaat ggtttttcag aaggctgagg atataaagga acggttgaac
    11281 aaaacagaaa gaagtctctg ggtaaataaa tttaaaatgc cgccaaatga ggcgaaaaaa
    11341 ctgcattcat tgctctttaa gaaagcaaag gcatactttc gtgaacagtc taaagagaag
    11401 cctaatccaa ctaatgcaga agtgctttgt tatattttaa gtggggaggt aaagtaaatt
    11461 ggctcgtccg gtttctttca gtagcagcga cttggcatgg gaatgtgcac aagtaaaaag
    11521 aaagctttta aatgatgtca aaaaggggcg attatcgcgt ctttcaaaat cagatgtgta
    11581 cgatatgatt gcaaaacgcc cgcgaatcag attgaaaagc tcgcgaatgt tgtggacggg
    11641 ttcctataag gaatatttgg aaaaatggtt caccaaattg aatgaggaaa tacaattaat
    11701 cctagactcg gcctctgaag gagaaccaac gattacaagt cctgagattg tagcccagga
    11761 gcaccgggaa ttgcaagcca aggttactca tttaacacag cttataagta cgtataaaga
    11821 tgctttggac gaattacgca tagagaacgg acagtaccga gaattaatca gccagcgttt
    11881 cggagatatt gacttattct aatgatcctg aatgtcccgt gtactgatac ccttcgcata
    11941 catatgtgct cctcaatgcc ggtcacattc gtttgatttt tcttcacgac tacaggttca
    12001 aattctacat caccgtattc ggaggttacg gttttcttac tgttgtagcc gtcgcggctg
    12061 tttctcgttt gtttgttttt acatcatgtt tctcataacc gggatgcgta tccagttcgg
    12121 cttctaatgc ttcttgaagt acatctgcaa ataattcctt taatgtccat tgaatatctt
    12181 ctgccgattg aaaattatgc tcttttacga attgacgtaa ttcttgtttt gacaataatc
    12241 cgcttcaggt caccatgtgc ttattcctcc aactttgatc tagtagtcag tattgacaaa
    12301 tttatctcag ttgaagtaaa gattatgtcc aaactaaatt gttacttcaa gccttgtacg
    12361 gaattgaatt acaaatgggt gaatctctcc cggagcgact attctttggt gtgacggttc
    12421 actcgcaatt aatgaaagca ggccgcgtga tagatttgag ggctgaacgc attcttatca
    12481 ttggaaataa aactgtattt catgaatata tccaatcgtt atcgagaatt ggtaatttgt
    12541 tagagaagaa gatcattgtt gtttatcttg gaggttttcc aggaccggat aaacgatttt
    12601 ttcttcggca aatccaagat aaatttgata aaaatggtct tcagattgaa gttcagtttt
    12661 ggggcgacat cgattgggga gggttccaaa tattccggca tttgcaaaaa tcagtgtttc
    12721 cacaactacg accctatcgt atggataaga ctactttcca tcagcatttg gattgggcag
    12781 aaaccttcac tgcagattat caagtcaaat tggagcagct actggaaaac acggataatt
    12841 cctagtttca cggattaatt cgagagatgt tgtgtacggg caagcgttta gagcaagaag
    12901 ctatattatt ataaactgta tttcagccac tggttgttgc cgaattctat aagattcgtg
    12961 gtaatacttt gtattgacag tgtatttcac aatagccgcg acttttgcgg cttttttcat
    13021 ttattgttat tagttgtttt cttggactgg gacaaaaatc aaaattgagc cttctatttt
    13081 taccataaaa atgcaagtaa atccgtaact ggccgatcaa ggaaacaagg ttgttaccag
    13141 gttggtgtag agcaaggtaa cgtctgggta tcttggcggc ttatttaaat gggggatgaa
    13201 gagccagttg cagactacat tctcagttcc cggctacagc aagcgatcaa agcgtgatcg
    13261 tgtgctgaca ccggcggtaa gcttgtccct agacaccaac aataaacagc acgcgattct
    13321 ccaagaccat gacatcttct tttatttatt ctttgtaccc ccggttgttt caaaaatgtc
    13381 atttgtaatc cgataaatca tgctgatttc ctctaagctt ttttgaatta gcagttcctg
    13441 aagcagttga atgacggtca ttttatttga acgtatgctg tctagttgaa tattctccaa
    13501 tcttagtaac tccagcatcg tcacatccaa agccctcgtt aatttatcca atgtctctaa
    13561 agaaacgttc acttctccac gctcgatttc gccgatatag gattgtgaca tatctacttt
    13621 ttcgccaagt tgctcctgtg acaatgatct cgctcttctg atttcgcgga ttttataacc
    13681 aataattgtc ttcagttcag acatgttact cgcctccaat attaggttag gcaagaacac
    13741 caaaaactaa catactgtta taacatctga aatattgatt ttaataacta aaacatctat
    13801 atttagggta taatttaatt taagtggtaa ggagctaagt taaaatatga atgttttacc
    13861 gacacagtca gtcatcgaaa atgttctgca gtataaaatg cgcggtaagg tagcatacct
    13921 aggtcatgta acggcttcag ttgctgttaa tttaacatat gtcaagccgt ataatgatcc
    13981 atctgggaaa ggatatcaga gaccagtaga tcccaaacgg tgccacgatt tttcgcttta
    14041 tttatcaaaa ggggacgatg ctttatttac tcccgttcta ctcaatgcca attcacaatg
    14101 agaatttgta gcgtatgata aatttagatc ttcgtatgga agattaattt gcaaaggtaa
    14161 agcatcttta atggacggcc aacatcgctt gggtgggata acaaagtaca ttaaagaaac
    14221 caattctgag cttaatgtgc catttctagc atttcattgc ttagacgaag acgaagaaat
    14281 tcgtttgttt gatgtcatca atacgaaagc aaaaggaatt ggttcgtctt taagtcgatt
    14341 tctgcgcaga gattcagatg agctaagttg ggtcgctacc gaattaatgg ttcagaatag
    14401 tagccccttt tttagtattg ggagtataat cgggaaacga aataaagata ggcatatcac
    14461 gctccaaaac ttatataaga cgcttcatta tctgacaaaa gaaccgcgaa ttgcttcttt
    14521 atccaaagaa gaaaaactat ctttatcttt gagttatttt gattctatta gacaaacatt
    14581 tgaaaacgaa tggagcaatt acaaggacta tcgactgaca catatcgttt gtttggatgc
    14641 tttgtcgatc gcaggatctg gaatattgga tagggcagta cacaatcaaa ataagcggtt
    14701 cgactacgcc ttaatagaaa aagccgtaaa aaaattaaag agagtggact ggtcgatgaa
    14761 tggcccgctg aaatatctta aagggctccc aggatcaagg agtttagcag aagaacttaa
    14821 ggaacaaatg ctaaaataat ttgatagagg tgtatacatg tctgggacga ataggagagt
    14881 tgagtcgcta gtcatagtag atccagaggg gaatctccag ccatttcatt ttattgacca
    14941 ttatagagag aatgaccaat tttattgtat tttacgtcac tataacgaaa ttaaaatttt
    15001 caagttggtt gaaaaagatg gagagtctgt tttgtttatg gcaccattgt gcgatgatga
    15061 ttcaaccgtt gtgccaactg aatataaaat tgccggcatc agttttgatg cattaacaac
    15121 agatagtcaa ttgtcctgta aattccaagt atcacaaaat ggaaaatcaa taaatataca
    15181 ggaatattta taaaaataga tgtttttcta ggattgtcag caggttcaat ggttggggga
    15241 ctgatcgtaa accattattc tgtcacgaca aattcctggg ttggcggact gattgttatt
    15301 ttagctatca tatcagcaat cttctcctta ataacaaaaa gcaaaggaat tgaccgttac
    15361 atcttaggaa aataataatt ggaactaacc acacctaatg agccaaacaa tagagcgacg
    15421 gtcggtgtca gtaagtgcat aaccgtcgcc ctgaatctgt gctggacttc gaatcgttct
    15481 aaatacccga ataaataata ttcctcaact ggatgaccag acttttgagc tctttctctc
    15541 tttccaaata atagagcgaa gcttgcagca acgggagatt cggttccgct tttctaacct
    15601 ccgtctggat aaaatggcaa agctcactca gctccgaacg atgcttggcg ctggacgaaa
    15661 gaatgttaag ggccgaatcc atctcccgga acagttcggt aaggatctgc tctttctccc
    15721 cttggcggtt cccgagcccc cagtttaaat acctctcgaa cgaagcttgt ttcagcagag
    15781 gcttcggatc ggaagccatc atatgcttaa cgagcacgtt gagcttgtca aaaataaact
    15841 ttgccgtttc ctcgagcgat aacgactttt cttcataaac aatccaaaat agatactcct
    15901 tcagaatcgc tcgatagatg gaaaccaaat cccacagata cggatggatt tcttcgccgt
    15961 acacatgcag caaacactca ctatgccatc ggatgagccg ccctctaacc ttgtgtctaa
    16021 gggggtggaa cttgggatcc tgttggatag ggagctccgt aaattcgacc agaatatgct
    16081 tgtattctat aaaataacgg aatcgaagaa tgatctgctg tataaactgc tcttccggcg
    16141 agagtccagg aaggcgcgtc agctcatcga cttgatcaaa atagtcgtta tggcattgat
    16201 caaacacctc gctgaatagg tcttccttgg aagggaaaaa tttatagacg gatcctttgg
    16261 caataccgca atcctcggca atatcctgta tcgtcgttaa aagaaaaccc cgttccttaa
    16321 aaagcctcgt cgccgatttt aaaacctctt cccttgtcac actcataaac aatgtctccc
    16381 cacttgacta tttttgaatc atagtacaaa atataagaca tcaagtcaaa tgaccaaatg
    16441 tttaatattt taaacttcag gtcaaatcca aagggtgagg agaacatata gaatggaaaa
    16501 attattggat ccgcaaaaaa cagcgttagt tgtcattgat ttgcaaaaat ggcttggtaa
    16561 tcaatacgcc ccttattccg ccgagcaggt agtatctaac gctgccgcct tggcagatgc
    16621 tttccgtgag caaggctcaa tggttgccct ggtccgggta tctagcaaag atctgaagga
    16681 tatcccgaga ccgaagttgg attcgcctgc accaccactg aatctgcctg aaggatggga
    16741 tcaaatcgtc ccggaaatgc gggtcgccga aacagaccac atcattacta aaaagcaatg
    16801 gggagctttt tacggaacgg agctcgacct gcagttgcgt cgccggggaa tcgacaccat
    16861 cgtcttatgc ggcatcgcta ccgggcttgg cgtggatacg accgcgcggg aagcgtttat
    16921 gaatgggtat cagctgattt tggcgatcga tgccatgacc gggttttctc aagccgagca
    16981 cgatcacgtg aaaaatttta tttttccacg catcgggcgt gttcggacaa cacaggaaat
    17041 catttctgcc tttgctgaag tttgaaccca aaggagatgt gcccttggat ttatcaggtt
    17101 ccaggggtcg tttttttatt tcaggaggtt ggtctctatg acccaaaaga gaagtcccaa
    17161 gtccgacagg atgtacccct ggtatgtctt atctgtaacc agtctcggag cgttcctggt
    17221 tctggtcaat atcggaacgc ttaatgtcgc attgccggaa ttaagccagc aatttcatgc
    17281 gaatgcggca gcttccagct ggattttact ttcctatatg ctggtaaaca ctatcctgat
    17341 tttaatcttc ggacaaattt cggatatttt cggaagaagc cgaatgtatt taataggaat
    17401 ggccatcttt accgtatcca gtttactact cggttatgct tttaatgtag aggtactaat
    17461 ccttcttcgg atcgtacagg ctgccggagg agcgctcgta gtgacgaaca caacaccgct
    17521 gattaccgat gcgtttcccc aatcgcagct gggcaccggt ctcggtctga atttattgtc
    17581 cgcttccgtc gcgcaggtgc ttggcccggt cgtcggcggc gtggtcacga ccgcctgagg
    17641 ctggaggtgg gtgttctggt ctaatgttcc cttcgggatc attgctctca tctgggggct
    17701 ctggattcta agggtgaagc ccctagcgca gctccataaa aaagtggacg gatatggagg
    17761 catcatgatc tttgtcgctt tagcgggtct aatcattgct ttatccaagg ggggagaact
    17821 gggctgggga gacaagcagg tgatcggagg ttttgcgata ttcgctatat ttactactat
    17881 atttttatgg catgagcatc gttcagcatc acctctacta gatttaagcc tttttgaaag
    17941 ctggacgttc agtatgggga acatcgctac attctttaat tcttttgccc gtacggcggt
    18001 tgctctgctc ttcgctctct attaccaatt tgccttccac caaaacgcgc ttaatgccgg
    18061 tctaaggatc cttccaatta cgatagggat gttggtcatt tctccgattg ctggcatgtt
    18121 gactaagaag gcggccattc gagttctggc ctcacttgga attcttattt ctatagcagg
    18181 actactacta ctcctattcg tggtcggtgg aaatttctct tacggggtca ccgcttgcgg
    18241 catgttgtta atcggggtcg ggaccggttt attccttacc cccaatacga cggagatcat
    18301 gtcaagcgtt ccggagcaaa gccgcggggt ggcgaatgga ctgcggtcca tgctatataa
    18361 cttgggtcaa gtgctgagta cggctctttc tttaaccatc gtcggcgcag cgctgccagc
    18421 ccacctgaag aacgtgctgt attccggaaa gaacaatgtg atttctgccg ttgattttgc
    18481 tttcgtcatt cacggttacc gctgggtcat catcgcacta atagggactt ctctactcgc
    18541 tcttgctgcc tcgtggttcc gtccgcaaca gaaaaaagct tacgaaagct cttcagcggc
    18601 ctcttgactt tgacgcattg atgccgcgtc aatccgtccg atcctcatcg atcggtcctg
    18661 cggctgccgc cataacccca gcgcgtccgg taagcccaaa cttctggagc tagcgatata
    18721 tatccggcgg gtagtggagc gttgacgata atattgctta ccaacctgta actaaagaag
    18781 tttttattag aaggatacct ttttacttct acaaacccga tacacgctca aaaaatgtag
    18841 gtggcttcct tgctataata cgttgctctc attttaagat ttccagcctg ataaaaattt
    18901 caagtaaagt agaacttatg acctattgga attattttca tattactgta ttatcattga
    18961 gtgtaaacat gatcgatcag gactttttaa aagaacacat aaaggataaa tacggatacg
    19021 aaagactcat cacttatttc tcaagacatg aagtaattgg ggaagaaatt tttccgtatc
    19081 ttggtactgc cattcactaa acggactggt atatttgcgt ttatgggagg atttcacgga
    19141 atgtcgctgg ggagtctggc tgttaccagc aacattcaga aaagatcttc ctccggcata
    19201 gcattatccg atgttacctt tttcccatac tccgagagtc caattgactc attcgatact
    19261 attgaataca tggaagccgt tctaaacgac ggtcactcgg gaatcgaaaa accggcggct
    19321 attatatttg aaaccattca ggcggaaggc ggcgtaaata tagcttcacc cgaatggatg
    19381 ctcaggctga gggaacttag cgacagacac ggtattctac tgatttgcga tgacattcag
    19441 gttggctgcg gacgcaccgg accgttcttt tcatttgaac gtgccgggat gatccctgat
    19501 attgtactgc tttccaagtc aatcagcggg tatggccttc ccatgtctat tctgctgatg
    19561 aaaccggaac ttgatgtctg gaagcctggt gagcataacg gtacgttccg gggaaaccag
    19621 cttgctttca ttggagctac agctgcgttg gaatattggg aaatgaataa tttggaacag
    19681 tctgtgaaat ataaggaagc atttgtaaga gaatatttaa ccaagcagat tttgtcatta
    19741 cataagggcc tgaccattcg gggtgcaggt ttgatttggg gtattgattt tttccaatgt
    19801 ggaggatgag cgaatcacgc aaaaagtagt agaggaatgt taccaaaacg gtttaatcat
    19861 cgaaagcgca ggaagaaaag acagtgttat aaaacttatg cctccgttaa ccatcgagct
    19921 tgaacttttg cagcagggtt gttcaattat cagacaagct attcaagaga atataaataa
    19981 agtattggag gtcgaaagtt atggataaaa tcgccattat aggaatagga tgccgtttgc
    20041 caggaggaat aagggggcct gaggagttct gggaagcatt gactgcggga aaagatatga
    20101 cttccgattt acccgaaggc cgctgggatt tagaaaagtt ttatgatcct gacaaatcaa
    20161 agccaggcaa gcattacacc tgtcatggtg gatttttaga taaaatagat gagtttgacc
    20221 ctttgttttt tggtatttct ccaagggaag cggcctttct tgatccacag caaagactga
    20281 tgctggagac atcatgggaa gcaatggaag atggaggctt ggatccggcc aagctagcag
    20341 gaaccaatac cggtgtcttt gtagcgggct tcacccttga ctatcaagca atacaattta
    20401 aaaacgaatc ggttgaaagt ttagatacac attcggcaac gggtatgatg atgacaatgt
    20461 tgtccaacag gatttcatat atatatgatt tcagaggtcc aagtttgtct gtagatacag
    20521 cgtgttcggg ctctttggtt gcaacacacc ttgcatgcgg gagtttattg aataatgaat
    20581 gtaatctcgc aatagcaggc ggagtaagtg ttatagctac acctgagtat accatagcgg
    20641 aaagtaaggg tggtttttta tctcccgatg gacggtgcaa aactttcgat tccagtgcaa
    20701 acggttatgc aagaggagaa ggagccggcg ttgtggtttt aaaacgcctg tcagatgcta
    20761 tcgaagacgg agataggatt tatgccgtaa taagtggatc gggtgtaaac caggacggcc
    20821 acacagacgg gattactgtt ccaaacgggc aggctcagga aaacttaatg aaggaggtat
    20881 acaaaaaggc aggaatatca ccttcagata taacatatat tgaagctcac ggcaccggca
    20941 ctccggttgg agaccctatt gaggctaatg caatagcacg agtggtttca acagacaggc
    21001 caaaagataa aaagtgtatt gtcggatctg ttaagacaaa cattgcccac cttgaggccg
    21061 ctgcaggagt tgccgcactg ataaaagctt cactaatcat aaagcataag caaatacctc
    21121 cacatctgca ctttaagaat ccaaacccta aaattccctt tgacgattta tgtatacgaa
    21181 ttcctcagac cctggagcct ttgccgcaac ccgcattggt tggcataaat tcattcggtt
    21241 ttggaggaac aaatgcccat atcctcttgg aggaagctac agatctccaa aaacagggta
    21301 ctcctgaagt taatgtaaat accggatggc catatatgat tcccatatct gcgcgctcag
    21361 aaaaggcgct aaaaaactat gcgcaaaagt atgttgattt tattaatgga agtggagaaa
    21421 gtatttcttt atatgatatt ggaagcatga tgagcaaaaa gcgcacccat catgactata
    21481 gactagcagt ttcggcatct tcaaaggaag aacttgcaga aaacctggaa gcgtatatta
    21541 aaggacaagc acgccagggg atgtctgcgg gaaatgttga ggcaggaaag tacaataaag
    21601 ctgtttttgt atatacaggt atggggccca tatggtgggc tatgggcaga cagctccttg
    21661 aaaaagaccc tgtgtttaga aatatgatag aaaaatgcga taaacttaca cgtcagtatg
    21721 ctggatggtc tctactggag gaacttctcg ccgatgagga gaattcacgt ctggaccagc
    21781 cccagtttgc tcaacctgcc aattttgctg ttcaggtggg tttgactgaa gtatggaaat
    21841 ccttgggtat tataccccat gcggtggtag gacacagtgt tggagaagtg gcttctacat
    21901 atgttgcagg aatttacagc cttgaagatg ccatgttggt aagtattcac agaagccgtg
    21961 cacagcaaaa agcagtaaac aagggcacaa tgctggcggt aggtttacca gaaaaagaag
    22021 ttgtggccct gctggatgag aacataaaag gtgtttcaat ggcagcaatc aatagcccaa
    22081 attcggtaac tttgtcaggt gatcctgatg cccttgagca gatccaaaaa cagttgcagg
    22141 ataagggggt ttttgcgcgg cttttaaagg tcaatgtagc gtatcacagt taccaaatgg
    22201 aaccatatga gcaggagcta ttggaggcat taaaaggaat aaagtcccag cctgccggga
    22261 taccgatata ttccacggtt acagggaaaa tgctgacggg tacagagtgt gatggacatt
    22321 actggtataa aaatgtaaga gagccggtac gttttgaagc agcaatgtat gaaatgattt
    22381 cgttgaatta taacttattt attgaggtgg gccctcaccc tgttttagca gcttctattt
    22441 ctaattgtct gtcagctaaa aacgttgaag gtaagaagtt gttctctata aaaagaaatg
    22501 aaaacgaaca ggtttcaata ctggagaact tagggaatct atatgcactg ggatacccta
    22561 tagattggaa caagatttac cggtatcaag gtgagtttgt aagtctccct ctttatccat
    22621 ggcaatggga taaatactgg atggaaacgc aggaatcaag tgaatttagg cagggaaaaa
    22681 ataagcacaa gtttttagga cgccgtttga aaacttccag ccctatatgg gagattgaac
    22741 ttaatactac ctatatgacg tatctttctg atcataaaat acaaggtata gaagttttcc
    22801 ccggagcagg gtatgtagag ctgggaatgg cttgtgccag aagctatttt ggagagggtt
    22861 tttatacagt tgaagatata aagtttgaaa atgctttatt tttaaatcaa ggagtatcac
    22921 ctgtggtgca ggtggttttg gatccaaaaa ccgcaaaatt cgagatttca agcaggatac
    22981 cgggacaaga taagacttgg acatgcaatg catccggcac aataagaaaa cggcaaaaca
    23041 taaagatcac tgctaaagat gagttgattc aaatacttgg caattgtacc aaagaatacg
    23101 gaaaagaagt atgttataaa accttctatc aaatgggttt ccattatggt ccttatttcc
    23161 aaggtataga caagatatgg aaaggtgata acgaagctct tggcaggatc gagatcccta
    23221 aaatactgga gattgatagc tctatctacg gtcttcaccc ggcggtattg gacgcctgtt
    23281 tccaggttac cattgcggca gttgcaccac ttaatgaaga tgaaaataac gaaggccaat
    23341 cattcctacc tgtaggaata gacagggtgc agctttatgg aaggccggag cctgtcatgc
    23401 tttgtcatac gcagttggta gataggaaag ataataattt gaacgccaac atccgtctat
    23461 atagtgagga cggaaatcta atcgccgaaa tactgggcat aagaactaag gaacttggaa
    23521 atagtggagg gtctgatgct ggaagagtta aggattatct ttatgagata aactgggagc
    23581 ttctaaaaag tgaagaagtt gatacccgca cagctgctgc taactctgga gcatggctta
    23641 tttttgtgga tcataaagca gcaggaaaag aactggcaaa tctccttgaa aaaaggggag
    23701 aagaatgctt tatggtatat cctggtgagg attttggttg gcagtatgaa gagcgtgaga
    23761 tatatataaa ccctcgaagc attgaggatc ttagatcgtt gtttgatgaa ttctcaaaaa
    23821 ttaaaacgaa gctaacaggt attgtatata tgtggagcct caatatcctt gagatccagg
    23881 aagttagcaa tacagctata gaaaaagctt gttttgaaaa cctgtttgta ttaaaacacc
    23941 tggtacaagc aaccacaaat ctgggattaa attttaagct gtgggttatt acaagaggag
    24001 cccaaatgat caacagggct actccaaatt ctgcattctt acagtcgttg gtatggggcc
    24061 ttggcaccgt cataggttac catgagttgc cttcaaattg gggaggcctt gtagaccttg
    24121 acatagaggc caatgcgggt gaaatggaaa tgctgttaaa agaagtctta ggtaatggag
    24181 agaaccaaat tgctttccgt aatgggaata gacttgcagc aagaatcgat aaactgcgga
    24241 ttgatatgca gcatcaagta cccgtacatc ttcgccccga tggaagttat gttattacag
    24301 gtgcttttgg tggcataggt atgattacag cccagtggat ggttgccaag ggagcaagac
    24361 atctggtact gcttggacgc ggagaatttc caaaacgttc tgaatggaac aatgtagagc
    24421 caggcagcag ccttgcagag aggattgagt ttgttcgtaa gctggagtcc cagggggcaa
    24481 cagtatatat tggatcagtg gatgtaactg atgaggaaaa gcttgctgga ttttttaaag
    24541 attttgataa ggaagaaagg cctcctattc gaggtgttgt acattctgct ggtattacgg
    24601 atgatcaatt tcttgaggtt agtaaagatg agacttttta tagggtcctt tcgcctaagg
    24661 taaatggtgc atggaacctt caccgtatga cagagggacg gcctattgac ttctttattt
    24721 tattttcttc agttgcttct gtatttggtt caccaggcca gggagcatat gcaactggga
    24781 atgccttttt ggactcactt gcacattacc gtttatcgag aggacttcct gcactgagta
    24841 tcaattgggg accatggtca gaggttggaa tggctgcaag gtttatggaa cgtgatccgg
    24901 agtattatat acaaaaatcc atagaatctg taacggtaga aaagggaatt agggctatgg
    24961 agcaccttgt tggagaagct gttgcacagt ctgtggttct acctatactc tcgtggcaaa
    25021 cgtttgggga aaaatggttc tcacccatga gttctccaca tgtgcttaaa actcttttgc
    25081 aagatgagtc aggacaacaa gagaatataa ataaatcaaa ggtggatgtt gatatcctgg
    25141 aggatattat ttcatctcca atacagagca ggcagaatat cgttgaaatg catattaaaa
    25201 caatagtagc gaaggttttg cgttataatc ctgaggatct aagtaccaaa caaccactaa
    25261 ctgtttttgg gatggattca ttaatggcca ccgaaataaa aaacaggatg gaggttgcct
    25321 ttaaaacacc tgtttccata gtagaacttc ttaagggttc cagcatatac gatctttccg
    25381 agcaaatgat atcaaagcta tacgaatcgg gaaagatttc agaacagggt tccctaaata
    25441 tgggtaaggc tgagcttgaa agaataccta aagtttctga aaaagagcac tatgaaacct
    25501 catctgcaca aaagatgatg tatatcatta ataatcttga gggtaacaac attgggtata
    25561 acatacctgt gggaatttta tttgaaggtg ggattgaaag ggttgccctt ggggaagcat
    25621 taaaaacatt gatacaaagg catgaagcat ttaggacatc ctttgagatg attgatgggg
    25681 agcttgtgca aaggatacaa gatgaagttg attttactat agaatatttt gagtctgagg
    25741 aagacggagt agagaaaata atcgatgaat ttgtaagacc gttcgattta agcaaagcac
    25801 ccttaataag agtaggtctt atagaaatcc atgctagcag gcaaatactt ttgcttgatg
    25861 tacatcatat agtctcggat ggaacttcaa taatcaggac ttttgatgaa atagtttcta
    25921 tattaagtgg tgaaagcctt ccggcaatgg aggtgcaata taaggatttt gcccagtggc
    25981 agaatggctt gtttagcact gaggtttaca aaaagcagga agaatactgg cttaataggt
    26041 tcaagggtga aattcctatc cttgatatgc ctacagatta tcctaggcct gtccttcaaa
    26101 gctttgaagg aaataggttg ctatttgatt tagacagtca tttgatggat aaattaaatg
    26161 tactttcctc ccaaacagga gccaccgtgt atatgatact tcttgcggca ttaaatacac
    26221 taatgtataa atactcagga caggaagaca taattattgg tactcctata gcggcaagaa
    26281 ctcattttga tactgaaaga atactgggga tgtttataaa taccctggca ttaaggaatt
    26341 tcccagaggg aaataaggcc tttactgagt tcttggaaga agtaaaagaa agctccttag
    26401 aagcatatga aaatcaggaa tacaggtttg atcagtttgt gacaaaactt aacgtaaaga
    26461 gagattcaag cagaaatcct ttatttactg ttatgtttaa tattgttcct tctgatgagc
    26521 atattatgga acatcgtggt gaattaaagt attccaaata tccggttgaa agtaaaacat
    26581 caaaatttga cctaacattc cagttgatac cagatggtca taatataata ttatggatgg
    26641 aatatgctac acgtctgttt aagaaggaga cggtagaaag gcttgttcag cattacttta
    26701 atatccttga agagataacc tcaaaccctg aaaaaaaact atcagaaatc aatatgttat
    26761 cccaagaaga aaaggagcga ataatatacg gctttaacga tacgaaggtt gaatttgaac
    26821 atcacctgac ggtacaccac ctgtttgagc agcagacgaa agtacgtcca gacaatatag
    26881 cagtagcgta tgaaggccgt agatttacat atggccagat caaccaaagg gcaaacagga
    26941 tagcaaggta catgctaaag gctggcactg gtagagaaga agccgtagtt gtcatgctgg
    27001 agaggggacc cttatttgta gaatcggtac ttggtatatg gaaagcaggg ggggcttaca
    27061 tacctgtaaa tccaaaatac cctacacaaa gggtgcttga tatatttaag gaatctaaag
    27121 ctgcctatgt gttgacctta tcagattatg tgacccagca gcttagtgag aactataaag
    27181 gccgaattat ataccttgac cagtgtgaaa aagagattga ggctgaaagt ggcgaaaacc
    27241 tagatctaga tatagacata aatagtttgg cctatgttat atatacatct ggttcaactg
    27301 gtgtaccaaa gggagctatg atagagcatc ttggcatgat aaaccacatc catgcggaaa
    27361 taaaggaact ttgtataact aacaacagca taatatccca gaactcgcct caatactttg
    27421 atgtatctgt atggcagttc tttgcagccc taaccatagg agctcaaatt atcatctatc
    27481 cagatgaaat agtaaaggat gttgcaaggt ttacgaatcg gatcatagaa gatggcataa
    27541 cggtccttga ggtggtacct tcataccttg ctttaatgct tgagtatgtg gaaaatacag
    27601 ggaataaacc ggaaaaactt cattacttgc tgataacggg agaaaccgta aaatccggca
    27661 tagtaaggaa atggtttgac ctatgtccaa atactaaagt agttaatgcc tacggacctg
    27721 cagaggcagc ggacgatatt actctatata ctatggaagc tgctcatgaa ggagagaaca
    27781 ttcctgtagg caagcctata caaaatatga atctatatat aacagataaa aacatgaacc
    27841 tgtgccctat cggagtaaaa ggagagatct gcgtctctgg aacaggtgta ggaaggggtt
    27901 atttaaatga ccctgaaaaa acagcccatg tattccttga agatcctttc agagaagaaa
    27961 aggggataag gctgtacaaa acaggagacc tgggaagatg gctgcctgac gggaatatcg
    28021 aattcctggg cagaatagac catcaggtta agatccgcgg ataccgaata gagcttggag
    28081 aaatagaagc tcagcttcta aaacattctt caataaaaga agttgtggca gcaacaaggg
    28141 aagaccccca agggaacaag tacatctgtg catatatagt tggagaaagt gaattgacaa
    28201 taccggaatt aagggagtat ctctccaaag atctgccaga ctacatgatc ccttcatatt
    28261 ttgtacagtt ggaaaaactg cctttatcag cgaatggcaa ggtagataga aatgccctgc
    28321 ctgcccctga tggaaatatt aatacagggg tagactatgc tgcaccattc ggtgaaattg
    28381 aggagaagct tgtactgata tggagccaaa tccttggagt ccagaagatt ggagtaaatg
    28441 ataacttctt tgaattagga ggagactcat taaaggcaac caatcttgta tcaagggttc
    28501 ataaagaatt tgacatagaa tttgcattaa aagaagtgtt tatgggtcct acaatttcgg
    28561 caatagcaaa aagtattaaa aatagactta acgatacagt ggaaatcgaa gaaattttaa
    28621 gcatgattga aaatctataa ataggaatta aaagagatga aatagagaag agggacgaag
    28681 ttatggataa tttgatgaaa agaatagaat ctctttctcc agaaaaaaga aagctatttg
    28741 agacgatgct aaaagaaaaa ggaaaagatg tttcaaaata tacgccaaat gccttttctg
    28801 gaataccttc tgccagagag caggaatttt accctatgtc atctgcccag aaaaggctgt
    28861 atatactaaa cgagcttgaa ggagcaggta ctgcatataa catgccaggc gtcgtactgc
    28921 tggaaggaaa cattgatgca gtacgcttcg aacaggcatt caaggagcta gtaaaaagac
    28981 atgaggctct gcgcacatca tttcatatgg ttgagggtga accagtacaa aaggttcatg
    29041 attacgtgga tttcagtatt acgtacctgg aactggatga agaaaaagca gcagaaatag
    29101 tcaaagaatt cataacgccc tttgatctta gccaagttcc attactgaga gtaggacttg
    29161 taaaaacgaa cgaagacagg cgtgttatga tgtttgacat gcaccacata gtatcagatg
    29221 gtatatcagt caatatactt atgagtgagt ttttggattt gtaccaaggg aagacccttt
    29281 tgccactacg gatacagtac aaggattttt ctgtatggca gaaggagatg tttgccggag
    29341 actcaataaa gaagcaggaa gaatactggc tccagacatt taagggtgat ataccggtac
    29401 tggatatgcc tactgactat ccaagaccgg cggtacaaag ttttgaagga gatgctgtaa
    29461 gctttgaaat aaaccctgaa ctttcagtca aactaaataa gcttgcaaca gataatggag
    29521 ctaccttata catggtactg atggctgcat ataacgtact cctgtccaga tacactggac
    29581 aggaagacat catagttgga agtcctgtag ccggaaggcc ccatgctgac ctgcagggta
    29641 tcattggtat gtttataaat accttggcca taaggaacta tcctgaggga gaaaagacct
    29701 tcgtccaatt cttgcaggaa gtaagggaaa atgcgttttt ggcttttgaa aatcagaact
    29761 accagtttga agaacttgta gaaaaactta atctcatgag ggacatgagc aggaatcctc
    29821 tttttgacac tatgtttgca ctgcgcactt caaacaagac agaatttgca gcatcgggta
    29881 taaacttcaa acaatacaac aactggctgg aaggcagaaa ggcaaaattt gaccttatgc
    29941 ttgaagtggt agagggtcaa gaaggtataa catttaacct tgaatattgt accaggctgt
    30001 ttaagaagga gacaataaaa aggtttggaa cccattacat ttccgttctt gaagagataa
    30061 cggcatgccc tgaaaaaagg ttgtgggaaa ttgatgtact gttacaggaa gaaaaacagc
    30121 aaatcctata tacctttaac gctacagagg cacagtatcc taaaaacaag actatccatc
    30181 agctttttga agagcaggca gagaagaacc ctgatcatgt agctgtggta tttgagggta
    30241 aaaagcttac atatagtgaa ctcaataaaa aatcaaatgg gttggcccat gtattaaggg
    30301 ctaaaggagt caaaccggac agtatcgtag gtattctggc agaacgctca cttgagatga
    30361 tagtagcaat cctaggggta ttaaaagcag gaggggcata tcttcccatg gatccagatt
    30421 atcctgagga aagaataagt catatgctgg aagacagccg ggcagtgatc ctgttgaccc
    30481 aatcacattt tatagacaaa tatacatcaa taggtacagt aataaattta gaagatgagc
    30541 aggaatattc agatgaacaa tataacttat cggaggtaaa taaaccttcc gatctagctt
    30601 acttaatata tacctcaggc tctacaggta aacccaaagg ggcaatgata gagcatagaa
    30661 acatagtaag gctgttattt aacagtaaaa tgcagtttga ttttaacgaa aatgatgtat
    30721 ggactatgtt tcattctatg agtttcgatt tttccgtatg ggagatgtac ggggcgttgt
    30781 tatatggggg cagattggtg gtagttccta aaatgacagc acgcagcaat gtagagtatc
    30841 tgagacttct aaggaatgag aaggtgaccg tattaaatca gacaccttca gccttctata
    30901 atatagccaa tgaagaagta tcatatgaag aaaaagaact taagataaga tatgtcatat
    30961 tcggagggga agcattaaag cctgcattgt tgaatgaatg gagaaagaag tacccgcaga
    31021 ctagactcat caatatgtat ggaataaccg agacaacagt gcatgtcaca tataaagaga
    31081 tagaagagga agaaattaga tctaatgtga gcagcatagg aaggcctata ccaaccctta
    31141 caacatatgt aatggataag aacatgaaag ttgttcccat tggagtagcc ggagagcttt
    31201 gtgtaggagg agacggagtt tgcagaggat atcttggaag accggagctt acaaaggaaa
    31261 agttcgttca aaatccgtac aagccggaag agaggttata tagatctgga gacctggtcc
    31321 ggttattatc tgatggagaa atggaatacc tgggtagaat agaccaccag gtaaagataa
    31381 gaggctttag gatagagctt ggtgaaatag aagcacaact gctaaagcat ccttcaattg
    31441 aggaatcttt ggtgattgca aaggaagacc atcagggcag taaatacctg tgtgcatata
    31501 tagcgggaga aaatgagctg acaatatcag aactaaggga gcatctctta aaagaactgc
    31561 ccgaatacat ggtaccatca tactttgtgc agcttgaaaa aatgccattg acagctaatg
    31621 gcaagataga caggaaggca ttgcctgaac ccgaaggtaa tataaatacg ggaatagagt
    31681 atgaagcgcc tataggcgaa tttgaagaga agcttgcact gatttggcaa gacatccttg
    31741 gaattaagaa gataggaaga aatgacaact tctttatgtt aggtggacac tctttaaagg
    31801 ctacaagcct tgtagcgaga attcacaaag agttcaatat agacatgcct cttaaggaaa
    31861 tatttaaggc tccaattata gcggaaatag caaggtatat gaaggaagca aaggagagta
    31921 tatatcaatc catccaaact gctaaagaga tggaatacta ccctatgtca tcagcccaaa
    31981 gaaggctgta tatattaaat cagtttgaag gagcagggac agcatacaat atgccaggca
    32041 gcttgctggt tgaaggcagt attgatctgg agctttttca gaagaccttc caacagctta
    32101 taaataggca tgagaccctt cgaacatctt tccatttcat agagggtgaa cccgtccaga
    32161 agatcaatga tcctgtgggt tttagtgtag tgtatctaga atctgacgaa gaaaaagtgg
    32221 gggaaatcgt aaaagaattt ataaagccgt ttgatcttgg aattgctccg ctgctaagag
    32281 taggccttgt gaaaacggga aaagacaagc atgtcatgat gtttgacatg caccatatca
    32341 tatctgacgg tacgtccatg gatatactgg tacatgagtt catggatatg tatggaggaa
    32401 ataacccttc ttccctccgt atacagtaca aggactattc tgtttggcag aaggaactat
    32461 ttgctgggga caaaataaag aagcaggagg aatactggct ccaggaattt aatggagaaa
    32521 ttcctgtgct gaatatgcca gtagattacc aaaggcctgc ggttcaaagc tttgacggag
    32581 gttttatccg ttttgaagca ggcagtgagc ttacgggaaa acttattaag cttgcaaggg
    32641 ataatggggc tactctttac atgacattgc ttgcttcata caacatactg ctgtctaagt
    32701 atacggggca ggaagatatt atagtgggaa gccctatagc tggaagacct catacagatt
    32761 tacaagacat aataggtatg tttgtaaata ctttagccat gaggaactat ccccagggag
    32821 aaaagacctt tgctgagttt ctaaaggaag taagggaaaa ctctataagg gcttatgaaa
    32881 atcaggacta ccagtttgaa gaactggtgg aaaagcttaa tgtaaagagg gatatgagca
    32941 ggaatcctct ttttgatact atgtttgtat tgcaaaatac cggctcatca gaattgaaga
    33001 tagataggct taagtttata ccctatacaa atgaatttag aatatccaaa tttgacttga
    33061 cattaaatgc tcgggaaacc caggaaggta ttgcatttga tttggaatat gccacaaggc
    33121 tgttcaagaa agagactgta gaaaggtttg cagcccatta ccttaatgtt ctggaagaga
    33181 taacggttta tcctggaaaa aggttgtcag aaattgatat gctttcacag gaagaaaagc
    33241 agaaaatact atatgacttt aacgatacaa aggtccggta tcctaaggat aagactatac
    33301 atcaactgtt tgaagagcag gtagaaaaga cacccaataa tattgctgta gtgtttgaag
    33361 ataaacagct gacttataag gaagtaaacg aaaaggcaaa ccaactggcc agaaaattaa
    33421 gagaaaaggg aataaaacct gatagtgtag tgggaattat ggtagaacgt tccccggaaa
    33481 tgatcatagg gatcatggct gtcctaaaag c
//
