LOCUS       NZ_JAFJXZ010000017     20549 bp    DNA     linear   CON 03-JUN-2024
DEFINITION  Paenibacillus polymyxa strain Hob6 Scaffold_17, whole genome shotgun
            sequence.
ACCESSION   NZ_JAFJXZ010000017
VERSION     NZ_JAFJXZ010000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 2906550)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Draft genome sequence of Paenibacillus polymyxa strain Hob6,
            isolated from hemp (Cannabis sative) seeds' oil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2906550)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2021) Plant Science Departement, McGill
            University, 21111 Lakeshore, te-Anne-de-Bellevue, Quebec H9X 3V9,
            Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-JUL-2020
            Assembly Method                   :: SPAdes v. 3.12.0; Medusa v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly :: GCA_000507205.2; GCA_014706575.1;
            GCA_000164985.2; GCA_000597985.1; GCA_002893885.1
            Genome Coverage                   :: 266.29x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017589695.1-RS_2024_06_03
            Annotation Date                   :: 06/03/2024 02:57:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,275
            CDSs (total)                      :: 5,119
            Genes (coding)                    :: 5,024
            CDSs (with protein)               :: 5,024
            Genes (RNA)                       :: 156
            rRNAs                             :: 21, 9, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 19, 2 (5S, 16S)
            partial rRNAs                     :: 2, 7, 15 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 44 of 95
            Pseudo Genes (incomplete)         :: 63 of 95
            Pseudo Genes (internal stop)      :: 13 of 95
            Pseudo Genes (multiple problems)  :: 21 of 95
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2587418
            Orig. end                         :: 2607967
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAFJXZ010000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20549
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="6"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20549
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20549
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10549](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10549
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     misc_feature    459..472
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.49"
                     /tool="antismash"
     gene            533..1996
                     /locus_tag="JYU28_RS22730"
                     /old_locus_tag="JYU28_22765"
     CDS             533..1996
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371436.1"
                     /locus_tag="JYU28_RS22730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22765"
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="WP_069011740.1"
                     /transl_table=11
                     /translation="MKKAYRFTALVLTAVILLLTGLPMLNAYGTEAKPQKKLVVGMSAD
                     FPPYEFYRVINGKKTIVGFDVEIAKEIAKDLNAEMVPEDMSFDSLLPALQSGRVDLVLS
                     GMTPTDERRKSIDFSDVYYHSKQVIMVRPEDKDKYSTMATLKGEKLGAQKGSIQEEIAQ
                     KVPNASVTSLDKISDLVLQLRTKRINAVVIEDTVAKGYTLDGTVTLAKAVPEDEGAETA
                     VGIRKGNTELLASVNKTLARLKAEGAIEKFSTEASALSADRQVSSNSIVDIFMKYRSLY
                     ATGIGYTLLLSALGVLFGFIIGLIISLLRMSGIRIIEWLGTTYVEILRGTPMLVQLMII
                     HYGIALTLGINFTPLQSGVITLSLNSSAYLAEIFRAGIQAVDRGQMEAARSLGMGRSKA
                     MRHVILPQAFKSILPAIGNEFITIIKESSIISTIGMVDIMYQAQVIKNITYEGLSPFVI
                     AAAIYFVMTFSLSKLLGLWERKLRASDHR"
     gene            1983..2705
                     /locus_tag="JYU28_RS22735"
                     /old_locus_tag="JYU28_22770"
     CDS             1983..2705
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371435.1"
                     /locus_tag="JYU28_RS22735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22770"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_029517461.1"
                     /transl_table=11
                     /translation="MITVKQLRKSFGKNEILKGIDIDIAKGEVVVIIGPSGSGKSTFLR
                     CMNLLEQPTDGEILFEGEPITARGHNINVTREKMGMVFQHFNLFPHKTVLQNLTLAPTQ
                     VRKQSGKEAEKIALELLRTVGLEDKKNTYPNQLSGGQKQRIAIARALAMQPHVMLFDEP
                     TSALDPEMVGEVLDVMKKLAEGGMTMVIVTHEMGFAREVGDRIIFMDNGQIVEQGAPDQ
                     VFGTPSHDRTRDFLAKVL"
     misc_feature    complement(2878..2896)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.99"
                     /tool="antismash"
     regulatory      2936..3104
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            3111..3779
                     /locus_tag="JYU28_RS22740"
                     /old_locus_tag="JYU28_22775"
     CDS             3111..3779
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687404.1"
                     /locus_tag="JYU28_RS22740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22775"
                     /product="3D domain-containing protein"
                     /protein_id="WP_029517462.1"
                     /transl_table=11
                     /translation="MKHLKHIGKTMKIAVLAAAIAGLAQTAGIADAASLHTAKEGDTFF
                     LLAQRYGVSVDELTKANPNIASSNIYAGLQIKVPGEKSVKAASESKPQLLTEKAAANEA
                     PTIEAWGKTFNYSKIVDVKASAYSAAADENGKWGAVDYYGNPLKLGTIAVDPNVIPMGT
                     KVLVTGYSHPGLPDHSFVAVARDQGSAITGKRIDIFIPGNKSFVNDFGFQNVKLYVIDK
                     "
     gene            complement(3973..4779)
                     /locus_tag="JYU28_RS22745"
                     /old_locus_tag="JYU28_22780"
     CDS             complement(3973..4779)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820724.1"
                     /locus_tag="JYU28_RS22745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22780"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_069011741.1"
                     /transl_table=11
                     /translation="MPYRGVLPCLALLLAFSSLPVHADAPPKIGTPHPKEAAVASSVHL
                     STDRATPTLAMLRKKHADIFKMCGPHTRQIALTFDDVPDSRYTPQVLDVLHANGIKATF
                     FIVGHRAEKHPGIIRRIIREGHAIGNHSYTHPDFRKATPERFRNQITKTERILQASAGF
                     RPKLIRPPYGEITEPQIKWARRHGYMIVNWNVDSLDWKGLSKTQIQRNVIPATGPGSII
                     LMHAGGGQSSNLQGTIQALPGLIHSLKAKGYKFVTVPRLLHTSERK"
     gene            5085..6107
                     /locus_tag="JYU28_RS22750"
                     /old_locus_tag="JYU28_22785"
     CDS             5085..6107
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371431.1"
                     /locus_tag="JYU28_RS22750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22785"
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_029517464.1"
                     /transl_table=11
                     /translation="MTDLFTPYQLKGLSLKNRIVMPPMCQFSVEAEDGNPTDWHHVHYV
                     SRAVGGAGLIIVEMTAVHPDGRITDRDLGIWSDEHIPAYRKIVEEVHKYGAKIGIQLGH
                     AGRKAEDAEQPVGPSSIPFSERLKKPHALKTAEVRELVQAYKEGARRAVEAGFDTVEIH
                     GAHGYLIHQFHSPLTNTREDEYGQDLSLFGVEVIHAVKEVLPADMPVLMRISAKEYVED
                     GYNVEYITGVGERYRDAGVDIFHISSGGEGPIGSGGGPSARAGYQVDLAHTVREKLNVP
                     VIAVGLLDDYEDARRVVQQKEADLVAIGRAMLRDPYWALHASRELKVQADIPEPYLRGF
                     "
     misc_feature    complement(5122..5135)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.67"
                     /tool="antismash"
     gene            6196..6864
                     /locus_tag="JYU28_RS22755"
                     /old_locus_tag="JYU28_22790"
     CDS             6196..6864
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432515.1"
                     /locus_tag="JYU28_RS22755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22790"
                     /product="PspA/IM30 family protein"
                     /protein_id="WP_069011742.1"
                     /transl_table=11
                     /translation="MSIFKRLRDLTMSNINAIIDKAEDPVKMTDQYIRDMQEDLEDAEK
                     AVAAQIAIEKRFKQQYEEQAALVKKREEQAHTAAKAQNVDLARRALEEKKSAEQKMNEF
                     KAGYEQNKASADNLRGKLDEMRRQLTEMKNKRETLVARYNAAKAQTEINKAMNGFSSDT
                     ATAGLKRMEEKMLQAEARAEASNEMSSKEKSLDEEFKELDKKSAVDDELAALLKQYENK
                     "
     gene            6996..7403
                     /locus_tag="JYU28_RS22760"
                     /old_locus_tag="JYU28_22795"
     CDS             6996..7403
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820726.1"
                     /locus_tag="JYU28_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22795"
                     /product="DUF350 domain-containing protein"
                     /protein_id="WP_013310484.1"
                     /transl_table=11
                     /translation="MHFLETMKAMLVWTGAGAILIFALMYVDSLFTKYKDFAEVKAGNM
                     AVTVRMIMKLVAQGYILSGSIATANNLLEALVYSVIAFVILLVLEVIVRLLLRYWAQFD
                     LDKGTQEGKIGFGLFSGALHLVGALIITACF"
     gene            7428..7934
                     /locus_tag="JYU28_RS22765"
                     /old_locus_tag="JYU28_22800"
     CDS             7428..7934
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010348250.1"
                     /locus_tag="JYU28_RS22765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22800"
                     /product="DUF4178 domain-containing protein"
                     /protein_id="WP_029517465.1"
                     /transl_table=11
                     /translation="MGVWKRISNLFAKPEPPKAEKSMLHLNPGDICEVSLVTYEVVGRV
                     HNRARNAVVLTLQDGNQISYLHIEERETLQFGLYQAIDGRLDNPEEVPTILELDDTTYH
                     LEEQYSGQVTVMGRAPFRQGGEQHVWQYQSDNYHLLRVEWQDGRFMLYEGEEVITGDVK
                     VIRAS"
     misc_feature    complement(7437..7451)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 24.68"
                     /tool="antismash"
     gene            7948..8703
                     /locus_tag="JYU28_RS22770"
                     /old_locus_tag="JYU28_22805"
     CDS             7948..8703
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310483.1"
                     /locus_tag="JYU28_RS22770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22805"
                     /product="DUF4247 domain-containing protein"
                     /protein_id="WP_029517466.1"
                     /transl_table=11
                     /translation="MSKRTWQYALKVFVALSLFVSVLSGCGAPSVKDTYPLESVSGSGN
                     STSYVYRAAGKTVPEVAEELKEQRTPEQMSPQSNERMFLVYSDEWYHLQQDPAKKEDTL
                     IEIDSKKYVEQNYSSSFLKGYLTATVLDALFDSLRGSGSYRGYSSRDVYRPSQGQYRAP
                     TVQEKKAIPPITVERKGSVTRRGKNSDSSVGSSGSLFDRGSSSSPSRGSISRDRSDSGG
                     SSIFDSPRKSYSKPKTRSGSGKISRRSRR"
     gene            complement(8843..9070)
                     /locus_tag="JYU28_RS22775"
                     /old_locus_tag="JYU28_22810"
     CDS             complement(8843..9070)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371426.1"
                     /locus_tag="JYU28_RS22775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22810"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_029517467.1"
                     /transl_table=11
                     /translation="MALSDNFKKLRIKYHLTQQELAEIAGVTNKAISAWESGLSEPRMG
                     AIEKIARHFHIKKSNIIEDDGIEHISSDQV"
     gene            9337..10050
                     /locus_tag="JYU28_RS22780"
                     /old_locus_tag="JYU28_22815"
     CDS             9337..10050
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820730.1"
                     /locus_tag="JYU28_RS22780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22815"
                     /product="hypothetical protein"
                     /protein_id="WP_069011744.1"
                     /transl_table=11
                     /translation="MLSAFLYIILGFFDALAAVTLVLKIYMLPVWENRRKILLYAIGIT
                     LFSFLMREVIGMPKLDFPLQYLLMVLFLRFGLGIKTYLAAFSAGSGLTAYINLQLFVYI
                     FANFFGVAQPGVISDTAGSSIYVIQLSSILTAYFISFVMGKYNFGFSFIIQPPHDFLKG
                     ENYLASLNKMFIIGSLISFVTIFVTLYMLYNSNTIGLLSISLLTFGISYFLSEKGDYED
                     ARNAIEAHRIRNKES"
     gene            10001..10549
                     /locus_tag="JYU28_RS22785"
                     /old_locus_tag="JYU28_22820"
     CDS             10001..10549
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /locus_tag="JYU28_RS22785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22820"
                     /product="accessory gene regulator B family protein"
                     /protein_id="WP_069011745.1"
                     /sec_met_domain="AgrB (E-value: 8.2e-22, bitscore: 74.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLETLSRHIASEIKKADPDGPTSVEVMEYAIGIKITEISAVLMVA
                     VIGWITGHFWGALLALATIMFVRRFSGGVHFSNLTLCVFFTTAICVTIPFVSLSLATIL
                     IINACSLLVIVLYAPNHFIYINKTKHHKYYKTICILVCILNFFIQSHIICLALIIQAFS
                     ILPLWKGGERKWIRNWREL"
     gene            10522..10653
                     /locus_tag="JYU28_RS26955"
     CDS             10522..10653
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427735.1"
                     /locus_tag="JYU28_RS26955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_256026089.1"
                     /transl_table=11
                     /translation="MDKKLARALSISLGKYANESTKKEKTIFGAKPVPAELKKTEKN"
     gene            10659..11393
                     /locus_tag="JYU28_RS22790"
                     /old_locus_tag="JYU28_22825"
     CDS             10659..11393
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820732.1"
                     /locus_tag="JYU28_RS22790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22825"
                     /product="hypothetical protein"
                     /protein_id="WP_069011746.1"
                     /transl_table=11
                     /translation="MEEGKRILATPLLDDNSLGDCSFFCENHLVAIELWKPKSNYHIPL
                     FHTSHGRFTVPTTLHECSVGLPTFCNLDGSNLVNITQVDKIITGDYGGGQVVFKNQDIK
                     ESINSANLSRWRQIYADAMNADREIRYIFGSEIKVVGKAAVSGFFKVMNMHSVDMWEPK
                     KNYYVPRFNSGDRSYTIGLTAQACREAFPYLYPAYKDTLINLDLVCEIESNAFGGLVRF
                     EGSDFTCSMSHNKLKALKKLWK"
     gene            complement(11663..11878)
                     /locus_tag="JYU28_RS22795"
                     /old_locus_tag="JYU28_22830"
     CDS             complement(11663..11878)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024835.4"
                     /locus_tag="JYU28_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22830"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_016820733.1"
                     /transl_table=11
                     /translation="MQKLTRGKCLLKEELKSHGRTQSWLARRTGYSRQQISNWIAGRDK
                     MSFEAAVLISRILECKAEDLYEWELA"
     gene            11967..12206
                     /locus_tag="JYU28_RS22800"
                     /old_locus_tag="JYU28_22835"
     CDS             11967..12206
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820734.1"
                     /locus_tag="JYU28_RS22800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22835"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_029517471.1"
                     /transl_table=11
                     /translation="MVADKNENVTCTSFYTIKMARLASGYSELIACNILGMSMNELKHI
                     EEDSSDLTIARAQQMSSLYEVSIDSIYFGKININ"
     gene            12402..13679
                     /gene="glp"
                     /locus_tag="JYU28_RS22805"
                     /old_locus_tag="JYU28_22840"
     CDS             12402..13679
                     /GO_component="GO:1990586 - divisome complex [Evidence
                     IEA]"
                     /GO_function="GO:0061599 - molybdopterin molybdotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="glp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371421.1"
                     /locus_tag="JYU28_RS22805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22840"
                     /product="gephyrin-like molybdotransferase Glp"
                     /protein_id="WP_029517472.1"
                     /transl_table=11
                     /translation="MNHTSLNAEKFQRKAVQVEEAQSRIASHVKQGEREDVGLEQAHGR
                     YLAMDLTAPHPYPRFRRSGMDGYAILASDTEVCSTGQEIWLHVIDEIPCGTVSDKRVET
                     GMAARIMTGAQLPEGADTVVMLEATQLREENGQTYVGLKKRMEVGKNVTQIGHEIKEGQ
                     LLLSKGTCVGAGHVSVLATFGVHRVPVYRKPRVAVFSTGSELLAVDEPLQPGKIRNSNT
                     YMLASQIREAGGEPFILQAIHDDLSLARTSVREAIAAYDIVVTSGGVSVGDFDIMGDLV
                     RQEDVNMLFNKVTMRPGSVTTAAVIDGKLLFALSGNPGACFVGCELFVRPTIQMMLSSA
                     HPYLQTWTAKLGADYTKVNNYTRFVRSSLEIRGGQVYAIPARADESSVMVTIKDSDCLI
                     VIPPTTEGLRKGEEVRVLVLQGGQVT"
     gene            13676..14224
                     /gene="mobB"
                     /locus_tag="JYU28_RS22810"
                     /old_locus_tag="JYU28_22845"
     CDS             13676..14224
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="mobB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371420.1"
                     /locus_tag="JYU28_RS22810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22845"
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="WP_029517473.1"
                     /transl_table=11
                     /translation="MNTKHPFVCQIVGFKNTGKTTFLGGLIRYVQKSGLRVAVIKHDGH
                     EFEMDHEGTDTYKHRQAGAEGVAIVSAGRTAILEENSQPVTSLIRHFQAYDCVLLEGFK
                     QEDYPKLVMVKEQSDAQLTDKLTNVQGVAVWEHQMDWAQHHYSDEMIQIFPAEANGPAG
                     RWLLEQIQKQIEGMRNKQG"
     gene            complement(14229..15329)
                     /gene="xerS"
                     /locus_tag="JYU28_RS22815"
                     /old_locus_tag="JYU28_22850"
     CDS             complement(14229..15329)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene="xerS"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687399.1"
                     /locus_tag="JYU28_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22850"
                     /product="tyrosine recombinase XerS"
                     /protein_id="WP_029517474.1"
                     /transl_table=11
                     /translation="MNIQKIIDRRKLDEKMPGLPWYVQQFMDYKLPDLSPSTLLEYVRD
                     YEAFFSWLRSEGLSAGETNAQVTLEELETLHMDSITGFRLFLSTKLEGSNSRITISRKL
                     SSLRSLFHYLSQIAEDENFYPLLKRNIMAKVEIKRIHKPKDTAAKLKGKILEEEELLEF
                     IGYIYEGYGQDLADNKQALYSYELNKERDACIASLILNSGLRVSEIVNLNLDDLDINNK
                     LLYVYRKGNNDETFKTPVYFREQSKDDLVLYLSLRHTRYRAPKKEKALFVTRPNGSTEG
                     KRMTKRAIQAMIIKYAKRFGKPYLTVHKLRHSFATDYYLQNDIYKTKEQLGHASTETTE
                     VYAHLTDKTMSQAIERRVETLSDSAD"
     gene            15446..15955
                     /locus_tag="JYU28_RS22820"
                     /old_locus_tag="JYU28_22855"
     CDS             15446..15955
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427739.1"
                     /locus_tag="JYU28_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22855"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_029517475.1"
                     /transl_table=11
                     /translation="MGYNIKSELKLSIKSVPESQKDIIVQLMQFYLYDFTAYLRIDVTE
                     KGTFPAYPDLYQYWTSGEQKLPFLIWRQDVPVGFALVDRMSSNREADYYMAEFFVLRPY
                     RHNGVGTWAAHELFGRFNGRWKVTQMSTNRPAQSFWRKVIGSYTKGEYREQTHPVRGNI
                     SQFFNT"
     gene            16125..17297
                     /locus_tag="JYU28_RS22825"
                     /old_locus_tag="JYU28_22860"
     CDS             16125..17297
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371417.1"
                     /locus_tag="JYU28_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_22860"
                     /product="M20 family metallopeptidase"
                     /protein_id="WP_069011749.1"
                     /transl_table=11
                     /translation="MLEKWVQELKDGEQELIAWRRHLHQHPELSFEETNTSAFIADQLR
                     SFGIEVRTNVGGNGVLGFLEGGQPGRTIAFRADFDALPIQDEKEVPYKSTVPGVMHACG
                     HDGHTAALLGVARVLSHNREALKGKLVFIFQHAEEKPPGGAKFMIEDGCLEGVEAVYGI
                     HLASEIPFGKIGLKSGPAMAAVDAFTIQINGKGGHGARPHQTVDSIVIGSQIVNGLQQV
                     VSRRVDPIESAVLTIGVFQAGTAFNVIADKAKIEGTVRTFNKEVRKEVENEIRSIVKGL
                     TEAYHAGYEMDYLNGYPSLVNAEAETERVRELIGRLYGADAFLDLKPVMGAEDFAYYLE
                     QRPGAFIHVGARNEDERTHFAHHHPHFDFDERALLVSGHIFLALALEYLQ"
     misc_feature    20155..20170
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 25.25"
                     /tool="antismash"
     misc_feature    complement(20476..20486)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    20527..20542
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.55"
                     /tool="antismash"
ORIGIN
        1 ttcggcaggt gtgccgtata cccgtacttc tccaccagtt tcgtcgatga tcgacttgag
       61 gccaacggca gcaccggtac tcatcatgca tatcagatgg tgcccacagg cgtgtcctaa
      121 acctttcaga gcatcatatt ctgccagaaa agcaacaatc ggtccggatt tttcagcttt
      181 gtaagttgca ataaaggctg tttctatgcc caaaacgggt gcctggacct caaaaccgtg
      241 aaaaatgagt tcttctttta aacgggcagc ggccagaaat tcctcgtttc caagttcagg
      301 atttgcccca atatataacg aaatgtcctt aaagcgtggg gcatgctgct caattgtctt
      361 ttgaatggtc tgtttaaaat ccatgctgaa aactccttta tataagctgt aatgtaggta
      421 ctgcgctagg tatgctgaaa ttgtactata acattcattg cataatcatg catattcatt
      481 tataatgaca caatcttatt tattataaag aatttaagga gagaaaaaaa gattgaaaaa
      541 ggcatatcgt tttaccgccc tggttttgac ggcggttatc ttgctgttga cgggtcttcc
      601 catgctcaat gcatacggaa cggaagcaaa accacagaaa aaacttgtag tgggcatgag
      661 tgccgacttt ccgccgtatg agttttatag agtcattaat ggtaagaaaa ccattgttgg
      721 gttcgatgtg gagattgcca aggaaatcgc caaggatctg aacgcagaga tggtcccaga
      781 ggacatgagc tttgattcct tgctgcctgc tctgcaaagt ggtcgtgtag acttggtact
      841 gtccggtatg acaccgacgg atgagcgcag aaagagcatt gatttttcgg atgtgtacta
      901 tcactccaaa caagtcatta tggtacgccc ggaggataag gacaaatatt caacgatggc
      961 tactctgaaa ggagagaagc tcggtgcaca gaaagggagt attcaggaag aaattgcaca
     1021 aaaagtgcct aatgcttcgg ttacctcatt ggataaaata tccgatctgg tactccagct
     1081 tcggaccaag cgtatcaacg cagttgtaat cgaagatacc gtggctaaag gatacacact
     1141 agacggtacc gtgacacttg ccaaggcagt acctgaagat gaaggtgcag aaactgccgt
     1201 aggtatccgt aaaggaaata ctgaattgct tgcctctgta aataaaacgt tggctcgcct
     1261 gaaagcggag ggggcgattg agaagttttc tacagaagcg agtgcactgt ctgccgacag
     1321 acaggtttct tcgaatagca ttgtagatat atttatgaaa taccgtagtc tttacgctac
     1381 gggtattggc tacactctgt tgttgtctgc actcggagta ttgtttggat tcattattgg
     1441 tctgatcata tccttgctgc gaatgagtgg tatacgtatc attgagtggt taggtaccac
     1501 atatgtcgag atcctgcgcg gtacacctat gctggtacag ctcatgatca ttcactacgg
     1561 aattgctttg acgctgggta tcaattttac cccactccag tcgggtgtga tcacattgtc
     1621 tctgaatagc tcggcatatt tggctgaaat tttccgtgcg ggtattcagg ctgtagaccg
     1681 tggacagatg gaagcagccc gttcgctcgg gatggggcga agcaaagcaa tgcgtcacgt
     1741 cattttaccg caagcattta aatctatact acctgctatt ggtaatgagt ttattacaat
     1801 cattaaagaa tcatctatta tttcgaccat tgggatggtg gatattatgt accaagccca
     1861 agtcattaag aatatcacct atgaaggatt aagtccgttc gtaatcgcag ccgctattta
     1921 ttttgtaatg acattcagct tgtctaagct gcttggttta tgggaaagga agttgagagc
     1981 cagtgatcac cgttaaacaa ttgcgtaaat cgttcggcaa gaatgagatt ttaaaaggca
     2041 ttgatataga tatcgccaaa ggagaagttg tcgttatcat cggtcccagc ggttcgggga
     2101 agagtacgtt tttgcgttgt atgaatctgt tagaacagcc gacggatggg gagattttat
     2161 ttgagggcga gccgattaca gctcgtggtc ataatattaa tgtaacccgg gaaaaaatgg
     2221 ggatggtgtt ccagcatttt aatctgttcc cacacaaaac agtgttgcag aacctgacgc
     2281 ttgcaccgac gcaggttaga aaacagtcag gtaaggaagc ggaaaaaatt gcattagaac
     2341 tcctgcgtac cgtggggctc gaggataaga agaataccta tccgaaccag ctatccggcg
     2401 gtcagaagca acgtattgcg attgcgcgtg ctttggccat gcagccgcac gtaatgctgt
     2461 tcgatgagcc gacttctgca ttggaccctg aaatggttgg agaggttctg gatgtaatga
     2521 agaagctcgc cgaaggcggt atgacaatgg taattgtaac gcatgaaatg ggctttgccc
     2581 gcgaggtagg cgatcgaatt atctttatgg ataacggtca aattgtggag cagggtgcac
     2641 cagaccaggt atttggcact ccaagccatg atcgcactcg tgattttctt gccaaagtat
     2701 tgtaagaaag tactgatcta atcataaaag agctctccgt tgacggaggg cttttctttt
     2761 tttgtcacca tttccccata ctttcgtaac aaatatagat ttcttgatga caaaattgta
     2821 acgagtgtag tatgatgttc agggttccca acattttcat gcggataagg ttacaaaatt
     2881 gtgatattat gcagtaagcc aaaacttacc gggacagcat gcggttagac aagcgctgaa
     2941 atgctggccc aaactatggg aagtgcgggg gacgtaacaa cggcagccat tccgatacgt
     3001 cataagacga tgaggaatat gcctaggggt gaattgcacg agcatagggc ttctcctgag
     3061 tccgaatccg acagctaact tcgcaggcat aaaagaggag gtacatatct ttgaaacatt
     3121 taaaacatat tggtaaaacg atgaaaattg cggtgcttgc cgcagctatt gcagggttgg
     3181 cacagacagc tggaatagcg gatgctgcct cgcttcacac tgccaaagag ggcgatacct
     3241 tctttttgct tgctcagcgt tatggagtat cggtagacga gctaacaaag gctaacccaa
     3301 acattgcctc cagcaatata tatgcaggtc tgcaaattaa ggtgcctggc gaaaaaagtg
     3361 taaaggcagc ttcggaatcg aagccgcagc ttcttacgga gaaagcagca gcgaatgagg
     3421 cgccaacgat tgaagcttgg ggtaaaacat tcaactatag caaaatagtt gacgttaagg
     3481 cttcagcgta ttctgccgca gccgatgaga atggtaaatg gggcgcagtg gactactacg
     3541 gcaatccgct taaactaggt acaattgcgg tagatcctaa cgtcattccg atgggcacga
     3601 aagtactggt tacaggctac tcccatccag gtttgccgga tcattctttt gtagctgtcg
     3661 ctcgcgatca gggcagcgcc attacaggaa agcggattga tatctttatt ccaggcaaca
     3721 aatcatttgt gaacgacttt ggatttcaaa atgtgaagct gtacgttatt gataaatagc
     3781 attgtacgta tatacagttt aattaaacat aatatatatt atgtaaacat aacgcctata
     3841 tccgtatata tctaggtcgg actcttatca ggtcctatcc gtaaaaaggc tgtcttgacg
     3901 agcagaatac ttctgctggt aagacagcct ttttacgttg ctttagcttg gacctcaatt
     3961 ataaacatac tgttattttc gttccgatgt gtggagtagc cgggggactg tcacaaattt
     4021 gtagccctta gcttttagag agtgaattag acccggcaaa gcttggatag tgccttgcaa
     4081 gttggaactt tgacctccac cagcgtgcat taaaataata gagccaggcc ctgtagctgg
     4141 aatcacattt cgctgaattt gtgttttact tagtcccttc cagtcgagag agtctacatt
     4201 ccagttgaca atcatgtagc catgacgacg tgcccacttt atttgaggct ctgtaatttc
     4261 accgtagggt ggacgaatca acttggggcg aaaacctgcg ctggcttgta aaatacgttc
     4321 tgtttttgta atctggttgc gaaagcgttc tggtgtagcc ttcctaaaat ccggatgagt
     4381 ataggaatga tttcctatag catggccttc acggataata cgacgtataa tccccggatg
     4441 cttttccgca cggtgaccga cgatgaaaaa ggtggctttg atgccgttgg cgtgtaatac
     4501 gtccaaaacc tgcggcgtat acctagaatc gggcacatca tcaaaggtta aggcaatttg
     4561 gcgggtgtgt gggccgcaca ttttaaaaat gtccgcatgt tttttacgca acattgctaa
     4621 tgtaggagta gctcgatctg tactcagatg tacagaagaa gcaacagctg cttccttggg
     4681 atggggcgtt ccgatcttgg gaggcgcatc cgcgtgaacg ggtaaacttg aaaatgctag
     4741 taacagtgcc aagcatggca acactcccct gtacggcata tgtatccccc cttttcgtgc
     4801 agtggtacct agtggtgctc tcgactatta tgtacctgtc ctattaaaaa tatgctggtt
     4861 accaagttag gctcataaac gtctggaaag aagttcgcga tgaaatgatt atcaatgaag
     4921 atgatggagc taaacgtaca tattctctta aacatgaccg aaaacaagag cattttcgca
     4981 agttttagcc ttacaacgga ttcggtatcc cgtgacagct ggtgtataat ggggttgcaa
     5041 ttcataatta tacagacatg gaattgaagg aaggaaggat aaaagtgacc gacttgttta
     5101 ctccttatca attaaagggg ctttctttaa aaaatcggat tgttatgccc ccgatgtgcc
     5161 aatttagtgt ggaggccgag gatggaaatc cgacggattg gcatcatgtc cattatgtga
     5221 gccgagcagt aggaggtgct ggtcttatta ttgtggaaat gacagcggtt catcctgatg
     5281 gacgtattac ggatcgtgat ttaggtattt ggagtgacga acatattcct gcatatcgta
     5341 agattgtaga ggaagttcac aagtatggtg ccaaaattgg cattcaacta ggccacgctg
     5401 gacgcaaggc cgaagatgct gagcaacctg tgggtccttc ttcgattcct tttagcgaac
     5461 gccttaaaaa gccgcacgcc ttaaagacag cagaagtcag ggaactggtt caggcataca
     5521 aagaaggcgc gcgccgcgcg gtggaagccg gttttgatac ggttgagata catggcgctc
     5581 acggctatct gatccatcaa tttcattcgc ctttaacaaa tacgagagaa gatgaatatg
     5641 gccaggatct gtcactgttc ggtgttgagg tcatacatgc tgttaaagag gttcttcctg
     5701 ctgatatgcc tgtgcttatg cggatatctg ccaaagaata cgtcgaagat ggatataatg
     5761 tggaatacat aacaggtgta ggggaacgat atcgtgatgc aggtgtggac attttccata
     5821 tctcttctgg tggcgagggt ccaattggtt ctggcggagg gccgtctgcg cgtgctggct
     5881 atcaggtgga tttagctcat accgtccgtg aaaagctgaa tgtacctgta attgctgttg
     5941 gattactgga tgattatgaa gacgcccgtc gggttgttca gcaaaaagaa gctgatctgg
     6001 tagcaatagg ccgcgccatg ctgcgtgatc cctattgggc gttgcatgca tcgcgggagc
     6061 taaaagtaca ggccgacatc ccagagcctt acttgcgcgg cttttagata atttttgaaa
     6121 ccctctttgc aaagcttgcg taaacatgtg tacagagctt aaaatttaag cattcaactc
     6181 taggaggaac ttcacatgtc tattttcaaa cgattaagag atcttacgat gtccaacatt
     6241 aacgccatta ttgacaaggc agaagatcca gttaaaatga cggaccaata cattcgtgat
     6301 atgcaagagg acctggaaga tgcagagaaa gcggtagccg ctcaaattgc tattgaaaag
     6361 agattcaaac agcaatacga agaacaggct gctttggtaa agaaacgcga agaacaggca
     6421 cataccgctg caaaagcaca aaatgtagat ctggcccgtc gcgcgctgga agaaaagaaa
     6481 tctgctgaac aaaaaatgaa cgagttcaaa gctggttacg aacagaacaa agcttcggcc
     6541 gataacctgc gtggcaagct ggatgaaatg cgcagacagc tgacagaaat gaaaaacaag
     6601 cgcgagacac tggttgcccg ttataacgca gctaaagcgc aaactgaaat taacaaagct
     6661 atgaacggtt ttagctctga tacggcaact gccggattga agcgtatgga ggaaaaaatg
     6721 ctgcaagcag aagcacgtgc cgaagcgagc aacgaaatgt cttctaagga aaaatcgttg
     6781 gatgaggagt tcaaagagct ggataagaaa agcgccgtgg acgatgagct tgccgctttg
     6841 ttgaagcaat acgaaaataa ataagaacat ttaagcagtg ccgccaagtt tgattgctca
     6901 ggaagcgaag gagaaacgtt ttctccttcg cttttccctg cccgcaggcg taaaacatta
     6961 tatgaaggtc aagaagatgt ggaggatggt atgaaatgca ttttttagaa acgatgaaag
     7021 caatgcttgt atggactggt gcgggagcta ttttgatctt cgcattaatg tatgtcgact
     7081 ctttattcac gaagtataag gattttgccg aagtgaaagc tggaaatatg gccgtaacgg
     7141 tacgaatgat tatgaagctg gttgcacaag gctatatttt gtcaggctct atcgctacag
     7201 ctaataattt gctcgaagcg cttgtgtatt ctgtgatcgc ttttgtcatc ctgcttgttt
     7261 tggaagttat tgtacgtctg ctgttgcggt actgggccca gtttgatctg gataaaggta
     7321 cacaggaagg taaaattggt ttcggcctgt tttcaggagc gctgcatctg gttggcgcct
     7381 tgatcattac agcatgcttc taggctaaga aaggcaggaa tataaccatg ggtgtttgga
     7441 aacgaatttc aaatctattt gctaagccgg agccgccaaa agcagagaaa agcatgcttc
     7501 acttaaatcc aggtgatatc tgtgaagttt cgcttgtcac ctatgaagtg gtaggtcgtg
     7561 tacataatcg tgcccggaat gccgttgttt tgacacttca ggatggtaat caaatcagtt
     7621 atcttcatat agaggaacgg gaaacactgc aattcggact atatcaggcc atcgacggca
     7681 gacttgacaa ccctgaggaa gtgccgacca ttttagagct ggatgataca acgtatcatt
     7741 tggaggagca atattctggg caagttaccg tcatgggccg tgctcctttc cgacagggtg
     7801 gagagcagca tgtttggcag taccagtctg ataattacca tttgttgcgg gtagagtggc
     7861 aggacggtcg ctttatgctt tatgaaggag aagaagtgat taccggagac gtcaaggtta
     7921 ttcgggcaag ctaggagagg gttacacatg agcaaacgca cctggcagta tgcattaaag
     7981 gtctttgtgg cgctgagctt gttcgtatcc gtgttaagcg gttgcggcgc gccaagtgta
     8041 aaggatacgt atccgctgga atcggttagt ggcagcggaa attcaacctc gtatgtatac
     8101 cgggcagctg gcaagacagt cccggaagta gcggaggaat tgaaagaaca gcgtacaccg
     8161 gaacaaatgt caccgcagag caatgagcgg atgtttctgg tatatagcga tgagtggtac
     8221 catttgcagc aagatccagc taagaaggaa gatacactca ttgaaattga cagtaaaaag
     8281 tatgtagaac aaaattacag ttcaagcttt ttaaaaggat acttaaccgc aactgtgctg
     8341 gatgctctgt ttgattcctt acgtggttca ggctcctatc ggggctactc cagcagagat
     8401 gtataccgac cttctcaggg ccaatatcgt gctcctacag tgcaggagaa aaaggcgatt
     8461 ccgccgatta cggtggagcg gaaaggttcg gttacccgta gagggaagaa ctcggattct
     8521 agcgttgggt caagcggaag tttgttcgac agagggtcca gcagttcacc gagcagaggc
     8581 tcgatttcac gtgaccggag tgacagcggc ggttccagca tatttgattc gccgcgtaaa
     8641 tcttatagta agcccaaaac acgtagcggt tcaggtaaaa tcagccgacg aagtcgacga
     8701 taatgggtaa aattttattt tcttctaaag ttgtttgcgg aactgtggag ctgttgcaca
     8761 gttccttttt tgtagtttga tataacctaa agtgaattga acggtgctcc tttgcttcga
     8821 ttttattgcc gtctactttg acctacactt gatcagagct tatgtgttca ataccatcgt
     8881 cttcaataat gttgcttttt ttgatatgga aatgacgagc tatcttttct atagcaccca
     8941 tccgtggttc agaaagtccg ctctcccaag ctgaaattgc tttattggta accccagcga
     9001 tctcagcaag ttcttgttga gtcaaatgat attttatacg taatttttta aaattgtcac
     9061 ttaaagccac tataatccct ccaccccaaa ttaagtagat tataaccttg atatcgaaaa
     9121 aaaaccaaca taatacatta gcaaaagcaa cgtcgctcac ttggggtgac tttttttgtt
     9181 agtataaatg ggtgtcgagt ttgaagaaga aagccagggg aagaaaattc cacctcatat
     9241 ttatacaaaa aaatccaatt tactagatta tttcattgcc acatctatta gtaaaatata
     9301 caattacatc aggcgaaata ggaggatggt gtaactgtgt tatctgcttt tttatatatt
     9361 atacttggtt ttttcgatgc tttagcggca gttactttgg tcttgaagat ttatatgctc
     9421 cccgtgtggg aaaatcgaag aaaaatactt ctctatgcaa ttggcataac tttgttttcc
     9481 tttctcatga gagaagtaat aggcatgcct aaattagatt ttccgcttca gtatttgtta
     9541 atggttctct ttttaagatt tggtttaggg atcaaaacat atcttgcggc tttttctgct
     9601 ggttccggtc ttacagctta cattaaccta cagctatttg tatatatatt tgcaaacttt
     9661 ttcggagtag cacagccagg tgttataagt gatacagctg gctcttctat atacgttata
     9721 cagttgtctt ccatccttac tgcgtacttt atttcttttg tgatgggtaa atataacttt
     9781 ggattctcat ttatcattca acccccacat gattttttga aaggtgaaaa ttacctagca
     9841 tctctaaata aaatgttcat tatagggtcc ctaatatcat ttgtcactat ttttgttact
     9901 ttgtatatgc tctataactc caatacgata ggattacttt ccatctcatt actaactttt
     9961 ggaatatcgt acttcttatc agagaaagga gattacgagg atgctagaaa cgctatcgag
    10021 gcacatcgca tcagaaataa agaaagctga tcctgatgga cccacaagtg ttgaagtgat
    10081 ggagtatgcg attggtataa aaattaccga aatttcagca gtgctcatgg tcgcagttat
    10141 aggatggata acaggacatt tttggggggc attactagct ctggctacga tcatgtttgt
    10201 aaggagattt tcaggagggg tacacttcag caaccttaca ctttgtgtct tctttacaac
    10261 ggccatatgt gtaactatac cttttgtctc tttaagttta gcaacgattt tgataattaa
    10321 cgcttgttca ttattagtga ttgtactata tgctcccaat cattttatct atattaataa
    10381 gaccaaacat cacaaatatt ataaaacgat atgtattttg gtttgcatat taaatttttt
    10441 tatacaatct cacataatat gtttagcttt aattatacaa gcattcagta ttcttccttt
    10501 atggaaagga ggtgagcgaa aatggataag aaattggcga gagctttaag tataagcctt
    10561 ggtaaatacg ctaacgagtc tacgaaaaaa gaaaaaacaa tttttggcgc taaacctgta
    10621 ccagctgagc tgaagaaaac agaaaagaac tgaatttaat ggaagaggga aagcgaatcc
    10681 tagccactcc attgcttgat gacaattcac ttggagattg ctcttttttt tgtgagaatc
    10741 acctagttgc gattgaattg tggaagccta aaagcaatta tcacattccg ctttttcata
    10801 cttctcatgg aagatttaca gttcccacca ccctccatga atgttccgta ggcttaccca
    10861 ctttttgcaa tttggacgga tctaatttgg ttaacatcac acaagtggac aagatcatta
    10921 cgggagatta tggagggggg caggttgttt ttaaaaatca agacattaaa gaaagtataa
    10981 attcagcaaa tttatctcga tggagacaaa tatatgcaga tgcaatgaat gccgatagag
    11041 aaattcgtta tattttcgga tcggaaatta aggtagtggg taaggcagca gtgagcggtt
    11101 tttttaaggt aatgaatatg cacagtgtgg atatgtggga acctaaaaaa aattattatg
    11161 tcccgcgttt caactctgga gatcgttctt atacaatcgg gctaaccgca caggcttgca
    11221 gggaagcttt tccgtatcta tatccagctt ataaagatac cctgataaat ctcgacttgg
    11281 tttgtgaaat tgagtctaac gcatttggag ggctggtacg attcgaagga tctgacttca
    11341 cttgctcgat gtctcataat aaacttaaag cgcttaaaaa actgtggaaa tgacccatga
    11401 aaattcaggg gtcatttttg ttaccagatt taaatgaata agtcaataat cagttagact
    11461 aggataagcc ggacgggttc gatttaattc gacatatttc ccgtttttaa tcattttcca
    11521 tgtgataaaa ttgattatga aaaaaataac aatcttttaa ataaaggtga aaacaatcta
    11581 catataagaa aaggagggtg aaagcgggat atatattgta aatgccggca tgtacaaatg
    11641 ccccgaagga aatgcctgtt tgtcaggcaa gttcccactc atataagtcc tcagctttac
    11701 actccaatat cctagaaatg aggactgccg cctcgaatga cattttgtca cgtcccgcga
    11761 tccagttgga tatttgttgc cgcgaatatc cagttcgtcg ggcgagccat gattgagtgc
    11821 gtccatgaga tttgagttcc tctttcaaaa ggcatttccc ccgagtaagt ttttgcacct
    11881 tacttgctcc taacagggga aaagtgtttc gttcagagta tacaggtaaa ttactttttt
    11941 atcaattata ttgtggagtt gattggatgg ttgcagataa aaatgaaaat gtaacttgca
    12001 ctagctttta tacaataaag atggcacgac tcgcttcagg atatagtgag ttaatagctt
    12061 gcaatatact tggtatgtca atgaatgaat taaaacatat agaggaagat tcatccgatt
    12121 taacaatagc tcgagcacag caaatgtcct cgttatatga ggtttcaata gattcaatct
    12181 atttcggaaa aattaatata aactaataaa atagagaaat gaccggatga tacgcaaaat
    12241 taaaaactga aatctaccaa aaacagccgc gatatgatat ccaggctgtt ttttggcgga
    12301 taaagacttg gagcaattca ataaataccg tttggatttg ccagataacg gttttagcgt
    12361 tataacagaa agagggcatt taagaagaac ggagtgagaa tatgaatcat acatcattaa
    12421 acgcagaaaa attccagcgt aaagcagttc aggtggaaga ggcacaaagc aggatagcta
    12481 gtcatgttaa acagggtgaa agggaggacg tagggcttga gcaagcacat ggtcgctatc
    12541 tggcgatgga tttgactgcg ccacatccgt atccccgctt tcgtcgttct ggtatggacg
    12601 gctatgcgat ccttgcctcg gacactgaag tctgttcgac cggtcaggaa atctggctac
    12661 acgtgattga tgaaattcct tgtggcactg tatcggacaa gcgggtggag acgggaatgg
    12721 cagcccgcat catgacagga gcacaactac ctgaaggagc ggacacggtg gttatgctgg
    12781 aggcgacaca gctgcgtgag gaaaatggac agacatatgt tggcttaaag aagcgtatgg
    12841 aagttggcaa aaatgtgaca caaattggtc atgagattaa ggaaggtcag cttttgctca
    12901 gtaagggaac ttgcgtggga gcggggcatg tctcagtact ggctactttt ggtgtacatc
    12961 gggtgcctgt ttacaggaag ccaagggtgg ctgtcttttc cacagggtca gaattgctcg
    13021 cagtggatga gccgttacaa ccgggaaaaa ttcgaaacag taatacatat atgctggctt
    13081 ctcaaatcag agaggcagga ggagagccgt tcattttaca agccattcat gatgatttga
    13141 gtcttgcccg tacctctgta cgtgaagcca tagctgccta tgatatcgtg gtcacgagtg
    13201 gaggagtatc ggtgggggat tttgatatta tgggtgacct ggtacgacag gaagatgtga
    13261 atatgctgtt caacaaagtt acgatgcgtc caggaagtgt gaccacagcc gcagtgattg
    13321 acggcaagct gttatttgcg ctttcaggca accccggtgc gtgctttgta ggctgtgagc
    13381 tgtttgtacg gccgacgatc caaatgatgt tatcttcggc acatccatat ttacaaacct
    13441 ggacggcgaa gttaggcgca gattatacga aggtaaacaa ctatacacgc tttgtacgca
    13501 gctctttgga gatacgtggt ggacaagtat acgcgattcc tgcgcgagca gatgaatcta
    13561 gtgtcatggt gaccattaag gacagcgact gtctgatcgt gattcctcct acaacagaag
    13621 gattacgcaa aggtgaagag gtgcgagtac tggtattaca aggtggacag gtaacgtgaa
    13681 tacgaaacat ccatttgtat gtcaaatcgt cggattcaaa aatacgggga aaacgacctt
    13741 tctcggaggg ttaattcgtt atgtgcagaa gtcaggtcta cgcgtagcag tgatcaagca
    13801 tgatggacat gaatttgaaa tggatcatga gggtactgat acgtataagc accgacaggc
    13861 gggtgctgaa ggcgtagcta ttgtttcggc tggaagaaca gctattttag aggagaatag
    13921 tcagcctgtc accagtctga tacggcattt tcaggcctat gattgtgtgt tgctggaagg
    13981 cttcaagcag gaggattatc cgaagctggt catggttaag gaacaatcgg atgctcagct
    14041 taccgataag ctgacaaatg tacagggggt agcggtttgg gagcatcaaa tggattgggc
    14101 tcaacatcac tactcagatg aaatgataca aatatttcct gctgaggcca acggacccgc
    14161 aggccgctgg ctactcgaac agattcaaaa gcagatagaa ggaatgagga ataagcaggg
    14221 gtgagacatc aatcggctga gtcgcttaga gtctctaccc gccgttcgat cgcctgggac
    14281 atggttttgt cagtcaggtg ggcatacact tctgttgttt ctgtcgaagc gtgccccagt
    14341 tgttcctttg ttttgtaaat atcattttgt aaataataat cagtagcaaa ggaatgacga
    14401 agcttatgca cggtaaggta aggcttaccg aaacgcttgg cgtactttat gatcattgcc
    14461 tgaatcgctc ttttggtcat ccgtttgcct tctgtactcc cgttaggacg tgtgacaaag
    14521 agagcctttt ctttttttgg agcgcggtaa cgggtatgtc tcagggacaa ataaagtacg
    14581 agatcatctt tggattgctc gcggaaatac accggcgttt taaaggtttc gtcgttattg
    14641 cctttgcgat acacatataa taatttattg tttatgtcta aatcatccag attcagattg
    14701 acgatttcag atacgcgcag gcctgagttc aaaatgaggc tggcgatgca ggcatcccgt
    14761 tccttattta gttcatagga gtatagcgcc tgcttattat cggccaaatc ctgaccatag
    14821 ccttcataaa tataaccgat gaattcaagc aattcttcct cttccagtat tttaccttta
    14881 agcttggccg ccgtatcctt gggtttatgt atacgcttga tttcgacctt ggccataatg
    14941 ttgcgtttga gcaatggata aaaattttca tcctcagcga tctgacttaa ataatgaaaa
    15001 agcgaacgca gagacgacag cttacgtgaa atggttatac gggagttgga gccttcgagc
    15061 ttagtagaca gaaataatcg aaagcctgta atactgtcca tgtgaagtgt ctccaactct
    15121 tcaagtgtaa cttgggcatt cgtttctccg gcagacaagc cttccgagcg aagccatgaa
    15181 aagaaagctt cgtaatcccg cacatattct agtagtgtgg aaggggacag gtcgggcagc
    15241 ttataatcca taaattgctg cacgtaccat ggtaatcccg gcattttttc atctagtttg
    15301 cgccggtcga tgatcttttg tatattcatt gggttccacc tcgtccggtc ataatatata
    15361 tgtattttag catattttga acagcactgg atgggatgta attcgaagtt aaagaacgga
    15421 ttgaaccgcc aagagaggtg aaagtatggg gtataatatc aaatcggaac tgaagctgtc
    15481 tattaagagt gtaccggagt cgcaaaagga cattattgta cagctcatgc aattttattt
    15541 atacgatttt acagcctatc tgcgaattga tgtcactgag aaggggacat tcccggctta
    15601 tccagacttg tatcaatatt ggacgagcgg cgaacagaag ttgccttttc tgatttggag
    15661 acaggatgtt cctgtgggct ttgcactcgt tgaccgaatg tccagcaatc gagaagctga
    15721 ctactacatg gctgagttct ttgtacttcg tccttatcgg cataatgggg ttgggacttg
    15781 ggcggctcat gagctgtttg gacgttttaa cggacgctgg aaggtgaccc agatgagtac
    15841 gaataggccg gcacaatcct tttggcgtaa ggtgattgga agctatacga aaggtgagta
    15901 cagggaacag acacatcccg taagaggaaa cattagtcag tttttcaata cctgaaaaat
    15961 tctaaataga taagttagta atgaaaaaga gttggggaga gtatcctatc ggctcttttt
    16021 tgttgtaaat tcaagtcttc tatgataaga gagctacatt ctacaggctg ttcatggtaa
    16081 gataaggata gaagcatata aattcaatag gaaaagaggg tattatgcta gaaaaatggg
    16141 ttcaggaatt aaaagatggt gaacaagagc tgattgcgtg gagaagacat ctacatcagc
    16201 atcccgagct ttcttttgaa gaaacgaata catctgcttt tatcgccgat caattgcgct
    16261 cttttggtat tgaggtaaga acgaatgtgg gtggaaacgg tgtgctcggg tttttagaag
    16321 gcggtcagcc aggtagaacg attgcatttc gtgctgattt tgatgcactt cctattcagg
    16381 atgaaaagga agtgccttat aaatcgaccg ttccgggtgt tatgcatgcc tgcgggcatg
    16441 atggtcacac ggctgcatta cttggagtgg cacgcgtgtt gagccataac cgtgaggcgc
    16501 tgaagggaaa gcttgtgttt atttttcaac atgcagaaga aaaaccgcct ggcggagcca
    16561 agtttatgat tgaggatggc tgtctggaag gggtagaggc ggtatacggt attcacctcg
    16621 cgtctgaaat tccttttggt aaaattggat taaagagtgg gcctgcgatg gcggctgtcg
    16681 acgcgtttac gatccagatc aacggtaaag gcgggcatgg cgcacgaccg caccagacgg
    16741 tagactctat tgttatcggc agtcaaattg tgaacgggtt gcagcaggtg gttagtcgca
    16801 gggtggaccc tattgaatca gcagtgttaa caattggggt atttcaagct ggaactgcct
    16861 ttaatgtgat tgcagataag gccaaaattg aagggactgt acgtacgttt aataaggaag
    16921 tgcgtaagga agtcgagaat gaaattcgca gtatcgtcaa ggggttgact gaggcttatc
    16981 atgccggata cgaaatggac tatttgaatg gctatccttc tttggtgaat gccgaagccg
    17041 aaacggagcg tgtacgcgag ctcatcggca gactgtatgg agcagacgct tttttggatt
    17101 tgaagccggt catgggagca gaggattttg cctattattt ggagcaacga ccgggagcct
    17161 tcattcatgt aggtgcccgt aatgaggatg aacgaacgca ttttgctcat caccatcctc
    17221 actttgattt tgatgagcgg gcattgctcg tctcagggca tattttttta gctctggcgc
    17281 ttgaatactt gcaataatat gcatttgttt atgactaaag ccagtattaa cggaagtaac
    17341 ggaagctgga accgcgcata gcgcggtttt tttgttgtaa atccaagtat tttgacaccc
    17401 ataaagaatg aaaataaagt aattaattca ctatgtgaaa aattcataat agaaataaat
    17461 aaaaggtgtt aactctgaag gaagtctaaa cctcatacta taagctgcgg agcaggagat
    17521 aatatcgcat gatcttgatt tttcgtacaa ggaaatgaaa aaaagatgac gaatctattg
    17581 agcatgacaa cagtgtaagc gctaacaaat tgggtgttgc actatattta ttgggatgaa
    17641 tgggggtgag tctaagagaa catttgtcag aattgtgaga agcaacgata acgataggaa
    17701 cgaattcgta tattcaaatg attatgaaga aggaggttga attcattgac taaggcaaaa
    17761 aacaggttga agattgcttg tttggcgctt gtggtagcgg gtgcttcctg gacaggaatg
    17821 atagcgccga ctcatgctgc ttcaagtgac gattacagtt ggaaaagtgt cgttacgggt
    17881 ggaggtggtg gttttgtacc tggcattatt tttaatgaaa cggaaaaaga cctgatctat
    17941 gcacgtacag atattggagg ggcttaccgg tggaatgctg ccaatgagag ctggattccg
    18001 ctgacggatt ctgtgggctg ggaggattgg aacaaaaatg gtgtcgatgc actagcaact
    18061 gatcctgttg atccaaaccg tgtatatata gctacaggta cgtatactaa ttcatgggat
    18121 aaacaaaacg ggcaaattat gcgttccacc gacaggggca atacgtggca gacgaccaag
    18181 cttcctttta aggtgggggg caatatgccg gggcgctcga tgggggaacg tctgacgatt
    18241 gatccaaata ggaataatat tttgttcttt ggagctcgaa gtggtaatgg actatggaaa
    18301 agctctgatt ttggagcaac ttggagcaag gtgagcagtt tcccaaatcc agggacgtat
    18361 gtacaggacc cttccaatga atataccagc gacattgtcg gtttagcctg gatcaccttt
    18421 gacaaaaaaa caggctcttc gagtaaagca acgcagacga tctatgtagg tgtagcagat
    18481 aaaaagcaaa gtgtctatcg cagtacagat ggcgggacaa cctggtctgc tatagcggga
    18541 cagcctacgg gctatttgcc acatcacggt gtgttatcaa cggacggcaa tctatatatt
    18601 tcttatagcg atggagccgg tccatatgac ggaacaaagg gtgaactgtg gaaattgaat
    18661 acagccagcg ggcagtggac taacattagc cccataggta gcagtagcgc ggacaatcat
    18721 tttggatatg gtggactgac ggtggatgcc cagaagccag gtacacttat ggttgctacg
    18781 ttgaatgcct ggtggccgga tgaaacgatt taccgcagca cggacagtgg ggcaacctgg
    18841 agtcctattt gggaatttga tggttatccg tctcgcaagc tgaaatataa tctggatata
    18901 agcggtgcac cttggctgac tttcaatgcc aacccggctc caccggaagt atcgcccaag
    18961 ctggggtgga tgatcggtga tctggagata gatccattta attcagacca tatgttgtac
    19021 ggcaccggag ctacgattta tggctctaaa aatctaacca attgggataa aggcggaaag
    19081 ctggatattt cagtagccgc taaaggggta gaggaaacgg cgattttgga tctggtgagc
    19141 cctccaaccg gcgcgccttt ggtgagcgca gtaggtgatg tctctggatt cagacatgac
    19201 gatttattca aggctccagc taaaatgctg gataatccga cttttacaag cagcgaaagt
    19261 attgattatg ccgagctgaa tccttctttt atggctcggg taggtaaagc ggattataaa
    19321 aaagatccaa atgccaaatc catcggtatt tccaatgatg gtggagccaa ctggtataag
    19381 gcaaatagcg agccttctgg tacagcagga gggggcagca tcgctgtagc agcagatggt
    19441 aatggcttgc tgtggagtac ctcagacaaa ggtgtgttct actccaaaac tggtggcaac
    19501 tcatggacag caagcacagg gattccagcg aatgcaaaga tcgtctctga ccgagtgaac
    19561 cctaataaat attacgcatt tgcctccggg aaaatatatg tgagcaccaa tggtggcgta
    19621 tcctttacgc cttcagcggt aactggctta ccgacagcag gcaatgctga tattgatgct
    19681 gtacgaggag cagaaggaga tgtgtggttc gccggaggct ccgaggatgg gggggcatat
    19741 ggtttatggc attccaacga ttccggcgct acgttcacca agctctctaa tgtgcaggaa
    19801 gcggattttg taggctttgg taaggcagcg ccgaaccgca cgtatgcagc ggtatttatc
    19861 gttggtaaaa tagatggtac acgtggattt taccgatcgg acgatgctgg tgcaaactgg
    19921 gcgcgcatta atgatgacaa acatcaatat gctcgagtga ccaaaattat tggggacccg
    19981 cgggtttatg gacgtgctta tctgggaacg aatggccgcg gcattctggt ggtagatcgt
    20041 gtgggtggtg atcagccatc taccgggcaa gcaagtatta caccaacgac tgcaacctat
    20101 ggagtgaata acaacaatac agatattact gtcaagctaa cacttaacgg caatacgctg
    20161 gaagcgatca agcaggggag tgtggtgttg aacaaaggtg aagattatac gcttagtgag
    20221 gatacagtcg ttcttaccaa caagtattta tctaaacttc ctaaaggaga gacagcacta
    20281 aacttccatt ttagtacagg caatgatgcg ttgtttacga ttacggtgaa aggggatacg
    20341 ccaagtgagc caggaacagg cgagggcgtt ctgaaggtgc aaaccttcaa tgggaatgta
    20401 tccaccacaa gcaatacaat cagttccaaa tttaaaataa ccaatacggg aacctcatcc
    20461 atttccctag cagatgtgac attgcgttat tattacacca ttaacgggga gaaaacacaa
    20521 aatttcttca cggattggtc gagcgtcgg
//
