LOCUS       NZ_JAFJXZ010000017     20924 bp    DNA     linear   CON 03-JUN-2024
DEFINITION  Paenibacillus polymyxa strain Hob6 Scaffold_17, whole genome shotgun
            sequence.
ACCESSION   NZ_JAFJXZ010000017
VERSION     NZ_JAFJXZ010000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 2906550)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Draft genome sequence of Paenibacillus polymyxa strain Hob6,
            isolated from hemp (Cannabis sative) seeds' oil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2906550)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2021) Plant Science Departement, McGill
            University, 21111 Lakeshore, te-Anne-de-Bellevue, Quebec H9X 3V9,
            Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-JUL-2020
            Assembly Method                   :: SPAdes v. 3.12.0; Medusa v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly :: GCA_000507205.2; GCA_014706575.1;
            GCA_000164985.2; GCA_000597985.1; GCA_002893885.1
            Genome Coverage                   :: 266.29x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017589695.1-RS_2024_06_03
            Annotation Date                   :: 06/03/2024 02:57:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,275
            CDSs (total)                      :: 5,119
            Genes (coding)                    :: 5,024
            CDSs (with protein)               :: 5,024
            Genes (RNA)                       :: 156
            rRNAs                             :: 21, 9, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 19, 2 (5S, 16S)
            partial rRNAs                     :: 2, 7, 15 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 44 of 95
            Pseudo Genes (incomplete)         :: 63 of 95
            Pseudo Genes (internal stop)      :: 13 of 95
            Pseudo Genes (multiple problems)  :: 21 of 95
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2229822
            Orig. end                         :: 2250746
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAFJXZ010000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20924
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20924
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20924
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10924](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10924
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            1170..1940
                     /gene="spoIIIAF"
                     /locus_tag="JYU28_RS20950"
                     /old_locus_tag="JYU28_20990"
     CDS             1170..1940
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822294.1"
                     /locus_tag="JYU28_RS20950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_20990"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_029517254.1"
                     /transl_table=11
                     /translation="MTWLAGWLKELVLIVLLASFVDMILPSRSMERYVKLVLSLLILLT
                     LLSPVVRLLSTSPSEVLGRALDLQRQAETGKREPTLEEILAKGSQLKLQQEQSSMQWAG
                     KEVAKEMKGQLEQYTGLAIQSVQVTLAKIQQEESGLEAGTGVQSVVVQLAEQQPEKEKK
                     NTDVSPGADVKPIMVEPVTEKTVNIRVEPTHAKTSDFNEGTRENDRNPDKTVEDGKPTD
                     TKAFGLITGLLREKWGIDSKNVQVLSSQDGTHEW"
     gene            1957..2598
                     /gene="spoIIIAG"
                     /locus_tag="JYU28_RS20955"
                     /old_locus_tag="JYU28_20995"
     CDS             1957..2598
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427500.1"
                     /locus_tag="JYU28_RS20955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_20995"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_029517255.1"
                     /transl_table=11
                     /translation="MSKWLKKLEQWLGGGADGAKRFNSFRWLLILGLIGVAIMLFNSFV
                     NVKKVDPENVGREPPGVMKNEPTLETTTGEESSFAGIEKVFEDNMKQMLEQIVGVGTVD
                     VMVTVDSTEEVIVQRNVKDMQEENNETDANGGQRHTTQYTRDGEIVTYESSGGQHTPIV
                     TKKVKPQVRGVLVVAMGAENPTVKQLIVDAVQKGLNVPSYKISVVPRKQG"
     gene            2661..3485
                     /locus_tag="JYU28_RS20960"
                     /old_locus_tag="JYU28_21000"
     CDS             2661..3485
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427501.1"
                     /locus_tag="JYU28_RS20960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21000"
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_029517256.1"
                     /transl_table=11
                     /translation="MNNKRQTVWLVSMLSLMVVLSAYYLFTEDSSPANPPVADSEQVSK
                     VKQDAAQEATTKAEEQLNELKVNEVVTNGEVTDGASANSTKSDTASTTDPATENSKGDK
                     GTAATPTTEPATSNQNTTATKTDATAQNDDKAASTAKTDQQVLDQVATDQAAQPTAAAV
                     IDNYLLERDVENQKKNDELTTAMNDSTPKKAAEAQKELHVLEDKQAKITGIEEELQQQF
                     ANAVVREEDADKYKVVVLSEKLDAKQAVTIVDKVMKELNVTQDKISVQYVTQ"
     gene            3624..4115
                     /gene="accB"
                     /locus_tag="JYU28_RS20965"
                     /old_locus_tag="JYU28_21005"
     CDS             3624..4115
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310822.1"
                     /locus_tag="JYU28_RS20965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21005"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_029517257.1"
                     /transl_table=11
                     /translation="MFKLSEIKELIKLVDETSVHELEIENEGTRLLIRKPGKSEIVTVQ
                     APVATPAYAVAPQAVIPNPQVQSDVGSTTAGEPREYASNLHKIVSPMVGTFYSSSSPDT
                     APYVSIGSKVGEKTTVCIIEAMKLMNELEAEVKGEIVEILAENGQLVEYGQPLFLVKPE
                     "
     gene            4177..5520
                     /gene="accC"
                     /locus_tag="JYU28_RS20970"
                     /old_locus_tag="JYU28_21010"
     CDS             4177..5520
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371779.1"
                     /locus_tag="JYU28_RS20970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21010"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_029517258.1"
                     /sec_met_domain="ATP-grasp (E-value: 1.2e-06, bitscore:
                     25.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 3.6e-07, bitscore: 27.2,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.1e-09,
                     bitscore: 33.9, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFQKVLIANRGEIAVRIIRACREMNISTVAVYSEADKDSLHVRL
                     ADEAYCIGPTLSKDSYLNFTNLMSVATLTECDAIHPGYGFLAENADFAEICESCNITFI
                     GPSPEAINKMGDKAVAKQTMKDAGVPVIPGSDGLVEDLQDAIGIARDIGYPVIIKATAG
                     GGGKGIRIAEDEDNLIQQITTAQQEAQKAFGNAGVYLEKYLTGMKHVEIQIIADKHGNV
                     AHLGERDCSVQRRRQKLLEEAPCPVLSQDVREEMGQAAVRAALAVQYSGAGTLEFLLGP
                     DNNFYFMEMNTRIQVEHPVTEMITGVDLIKEMISVAEGHPLSFTQEEVTINGWAIECRI
                     NAEDPDRNFMPAPGKIGFYLPPGGPGVRVDSAVYPGYSIPPYYDSMIAKLIVWAPTRQD
                     AIAKMKRALTEFAIEGIPTTISFHQRLLEHPTFIKGDFDIKFLEENEV"
     gene            5646..6059
                     /locus_tag="JYU28_RS20975"
                     /old_locus_tag="JYU28_21015"
     CDS             5646..6059
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430927.1"
                     /locus_tag="JYU28_RS20975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21015"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_029517259.1"
                     /transl_table=11
                     /translation="MSTVPTEFERTEIGEIQIAPEVIEVIAGLATVEVPGVAGMSGGFA
                     GGFAELLGRKNLSKGVKVEVGQREAAVDVSVIIEYGNRLPEVAAAIQHNVKRSIENMTG
                     LNVVEVNVQIHDVQFKNADKVEEPEVLGAGRVK"
     gene            6133..6672
                     /gene="amaP"
                     /locus_tag="JYU28_RS20980"
                     /old_locus_tag="JYU28_21020"
     CDS             6133..6672
                     /codon_start=1
                     /gene="amaP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282227.1"
                     /locus_tag="JYU28_RS20980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21020"
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="WP_029517260.1"
                     /transl_table=11
                     /translation="MAKVMDRLLLFLYSLSIGIISILAILLLSGAIPYVLSIEDERVVW
                     FTSLIIAGVLLLLSLRFFYISIRRNQTVQHSIDQRTEYGDIQISVDTIENLCLKAASRF
                     RGMQDLKARVRVLDSGLDITIRAVVDGESSIPVLTSEVQKGVHDHVEEITGIPVSNVSV
                     YIANVSQSPSFKSRVE"
     gene            6688..6921
                     /locus_tag="JYU28_RS20985"
                     /old_locus_tag="JYU28_21025"
     CDS             6688..6921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282226.1"
                     /locus_tag="JYU28_RS20985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21025"
                     /product="DUF2273 domain-containing protein"
                     /protein_id="WP_023989248.1"
                     /transl_table=11
                     /translation="MPWKEIWGSYKGRIMGITAGIFFGFIYLWAGFWNMLFFALMVFIG
                     YTLGRRSDSALGSFLPWKEWGDWLSQRWRPFK"
     gene            7058..7507
                     /gene="nusB"
                     /locus_tag="JYU28_RS20990"
                     /old_locus_tag="JYU28_21030"
     CDS             7058..7507
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310817.1"
                     /locus_tag="JYU28_RS20990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21030"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_013310817.1"
                     /transl_table=11
                     /translation="MKRRLARELAVQSMYHMEMNEVDAAAAVDMLLQEAAEENEAEVVV
                     KNAAVLRAYVLEHVRGTWEHKEAIDGLLVDYLKGWQISRLSRVDRQILRLAAYEMIFRE
                     DVPAKVAVNEAIELSKHFGTEESGKFVNGVLGRVIQELEQLKARF"
     gene            7545..8402
                     /gene="folD"
                     /locus_tag="JYU28_RS20995"
                     /old_locus_tag="JYU28_21035"
     CDS             7545..8402
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345647.1"
                     /locus_tag="JYU28_RS20995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21035"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_029517261.1"
                     /transl_table=11
                     /translation="MSAPIIDGKQISQDIRASIQQEVIRLKEHSFQPGLAVVLVGEDPA
                     SQVYVKNKEKACHDLGYYSEVHRLAADTSQEALLELVNKLNHQSTIHGILVQLPLPKHI
                     HEKAVIDAIAVEKDVDGFHPVNVGNLVIGDDSLLPCTPAGVIELIKRAGVEIAGKHAVV
                     IGRSNIVGKPVSLLLQRENATVTMCHSRTANIADLSRQADILVVAIGKANFIDASFVKP
                     GAVVIDVGMNRLENGKLAGDVDFESVKQVSGPITPVPGGVGPMTITMLMQNTLVAAKRS
                     HGLA"
     gene            8415..9779
                     /gene="xseA"
                     /locus_tag="JYU28_RS21000"
                     /old_locus_tag="JYU28_21040"
     CDS             8415..9779
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345648.1"
                     /locus_tag="JYU28_RS21000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21040"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_081317622.1"
                     /transl_table=11
                     /translation="MAEQRIYSIKDLNRYIRMKLESDQVLSDVWIRGEISNFTHHSSGH
                     MYFTLKDEGSRIRSIMFATHNQRLPFVPKEGTRVIARGNVSVYERDGQYQFYATQMQPD
                     GIGSLYLAYEQLKQKLDAEGLFDTARKRSLPAHPVTIGVITSPTGAAVRDIITTLQRRY
                     PQAGIVLYPVLVQGKGAAPSIVKAIETMNRMQEVQVMIVGRGGGSLEELWAFNEEAVAR
                     AIYASVIPVISAVGHETDFTIADFVADLRAATPTAAAELAVPNQAELRDQLLQREQRLR
                     NALRQRLETSRVRLARLQRSPVLLHPRRYMLQHAERMDMLHQRLIRAARNRSRLNAEKN
                     ARMRQVLERFNPREQIRSARKQTDMAQRQLESAMRAITKTGRQQLHTGIRQLDALSPLK
                     VMARGYSLVYDEQEKRLIKSLKDVQPGDSIKIKVSDGQLDCQVWGMKEDAKHGGE"
     gene            9769..10029
                     /gene="xseB"
                     /locus_tag="JYU28_RS21005"
                     /old_locus_tag="JYU28_21045"
     CDS             9769..10029
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371773.1"
                     /locus_tag="JYU28_RS21005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21045"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_013310814.1"
                     /transl_table=11
                     /translation="MANETELNFEAAMAALEEIVGQLEHGDVPLEQAIDLFQRGMKLSQ
                     LCSQKLEQVERKIEMIVEEDGDLRKKPFGGGLDENGGEGLE"
     gene            10001..10924
                     /locus_tag="JYU28_RS21010"
                     /old_locus_tag="JYU28_21050"
     CDS             10001..10924
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430919.1"
                     /locus_tag="JYU28_RS21010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21050"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_069012726.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.9e-57, bitscore:
                     190.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTAVKDLNRPSFKEYLTGTTDAVSSALTEQFPADWDIPDVLRES
                     MNYSLTAGGKRLRPLLVIAAAEAFGGSREAALPVACAVEMVHTYSLIHDDLPAMDDDDY
                     RRGKLTNHKVYGEAVAVLAGDALLTHAFYSIVQAGRRHGVSSDSLLSIVEDLSEMSGAR
                     GMVGGQVADMSGEQGMTGIEELEYIHLHKTADLIIFSLLAGGRIGGADKGQLEALRRFG
                     RDLGLAFQIQDDILDLIGDESKMGKKTQSDVEQEKVTYPYFIGMDASLQQVEELTASAK
                     RVIIESGIPDSSRLLEIADYLMKRDH"
     gene            11032..12930
                     /gene="dxs"
                     /locus_tag="JYU28_RS21015"
                     /old_locus_tag="JYU28_21055"
     CDS             11032..12930
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345650.1"
                     /locus_tag="JYU28_RS21015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21055"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_029517266.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 5.1e-125,
                     bitscore: 413.4, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.2e-07, bitscore:
                     26.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLPHIKQPGDLKSLSVEELASLAEEIRSFLIEKLSVTGGHLASN
                     LGVVELTIALHYCYNSPKDKMIYDVGHQAYVHKILTGRMDRFDTLRQRDGLCGFVKRSE
                     SEHDVWEAGHSSTSLSAAMGMALARDLKGEDNKVIAMIGDGALTGGMAFEALNHIGHER
                     KNLMVILNDNEMSIAPNVGAMHNYLSKIRSDRHYLRAKDELEVLLKKIPAIGGKLAKSA
                     GRVKDSLKYMMVPGVLFEELGLTYLGPVDGHDLPKLIETFQQADNVTGPVLVHVVTTKG
                     KGYKPAEADSHKWHGISPYKIESGQVLKAVGNPMYTEIFGRTLIELAEQDERIVAVTPA
                     MPGGSGLVPFSKEFPSRMIDVGIAEQHAATMCAALAMEGMKPVFAVYSTFMQRAYDQIV
                     HDICRHNANVMFAIDRAGFVGADGETHHGVFDVAFLRHIPNLVLMMPKDENELRHMMKT
                     ALDYEDGPIAYRYPRVNVVGVPLDKELQAIPIGSWELLRKGEGFAVIASGPMLQVATEA
                     AEAMKREGLQVGVVNARFLKPLDEDMLRELARQHTKLIVLEEASEAGSLGSAVLEFYAK
                     AEIQEAQVRLMGIPDLFVEHGSIKEQRAEVGLTIEDVCLKLRKWAAEPAYGMGQSV"
     gene            13007..13858
                     /locus_tag="JYU28_RS21020"
                     /old_locus_tag="JYU28_21060"
     CDS             13007..13858
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310811.1"
                     /locus_tag="JYU28_RS21020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21060"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_029517267.1"
                     /transl_table=11
                     /translation="MSVPKERIDVLLVEQGFFESREKAKAAIMAGLVLADSERIEKAGM
                     KVPRASELKVKGSVHPYVSRGGLKLEKAIRQFELDMKGRTMLDIGSSTGGFTDCALQHG
                     AEYVYAIDVGYNQLDWSLRNDERVCVMEKTNFRYMTPADLNGSVPNFASIDVSFISLRI
                     ILPPLLALLHQPADIVALIKPQFEAGREKVGKSGVVRDPATHKEVLQTILMFAHELGLT
                     LQGLAYSPITGGEGNIEFLAHWRLDGFPAAESQLEKMDFRPLIERTVQEAGQTFNNGPS
                     RK"
     misc_feature    complement(13927..13940)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.89"
                     /tool="antismash"
     gene            14014..14490
                     /locus_tag="JYU28_RS21025"
                     /old_locus_tag="JYU28_21065"
     CDS             14014..14490
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282218.1"
                     /locus_tag="JYU28_RS21025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21065"
                     /product="hypothetical protein"
                     /protein_id="WP_029517268.1"
                     /transl_table=11
                     /translation="MDTRYDTVIIAVIGVILGIWALYSLRAWLKEPEPLVLKTIPINED
                     LDEGPATHLLEEAGYEVVGGKMKIPLAFKVNGHTVYSRLFIDYVAVRNGSTYMVKTSRR
                     KKPMEWSGPDLRDRLMPYLLLYPGCAGVLYVDTDERSIRLITLVEDLEEEEYEG"
     gene            14507..14956
                     /gene="argR"
                     /locus_tag="JYU28_RS21030"
                     /old_locus_tag="JYU28_21070"
     CDS             14507..14956
                     /codon_start=1
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014282217.1"
                     /locus_tag="JYU28_RS21030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21070"
                     /product="transcriptional regulator ArgR"
                     /protein_id="WP_013310809.1"
                     /transl_table=11
                     /translation="MKGQRHIKIREIISQHEIETQDDLVEALRKAGFQVTQATVSRDIK
                     ELLLIKVPMDDGRYKYSMPSDQRYNPAQKLKRTLVDNFLHIDYTTNLIVMKCLPGTANS
                     IAALLDNIEWSEIMGTISGDDTILIICRSEENSEAIVNRLMGYIS"
     gene            15015..16733
                     /gene="recN"
                     /locus_tag="JYU28_RS21035"
                     /old_locus_tag="JYU28_21075"
     CDS             15015..16733
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371767.1"
                     /locus_tag="JYU28_RS21035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21075"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_069012725.1"
                     /transl_table=11
                     /translation="MLVTLSIRNLAVVEAVDVHFYKGFHVLSGETGAGKSIIIDALGLI
                     AGGRGSADLVRYGCDKAEMEALFELPVKHPVWNTLEEQGIKANAEEHLLIRRELTVQGK
                     SSSRINGQMVNLTMLREVGEQLVNIHGQHEHQSLLRADRHLALLDTFGDSVIGPVKTLY
                     RERYNAFVKAEKEVRELQSSSQKAYQLLDMYRFQLEEIAAAELKLGEDELLAEERVKLS
                     HSEKMMDGISGAYELLSGRGGLDTINNVLTRLNDVQNYDSKSLQPIAEQIQSAFYQLED
                     AAFQLRSYREDIEFNPGKLHEVEQRLNQITGLQRKYGDSIEQILEYYSRIEQETDLLEN
                     KDERLEQLIAKRDELLSDLLEISEELTEAREICAEELAEQVEQELKDLQMERTSLKVRI
                     DPIEDPRGYEYKGLKVRPTKQGIDNAEFLISPNPGEPLRPLGKIASGGELSRIMLAMKS
                     IFARHDQIPVLIFDEVDTGVSGRAAQSIAEKLYRLSSVCQVFSITHLPQVACMADHQYL
                     IEKNVHDGRTMTQIEGLTEDGRVKELARMLGGVEITEKTLHHAQEMLNLAEGKKA"
     gene            16857..18017
                     /gene="spoIVB"
                     /locus_tag="JYU28_RS21040"
                     /old_locus_tag="JYU28_21080"
     CDS             16857..18017
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014599992.1"
                     /locus_tag="JYU28_RS21040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21080"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_069012724.1"
                     /transl_table=11
                     /translation="MNFYSRIKLLGLLLVFLMCSIGNAQHVQAALPPQASLDLFGSKSV
                     RTTQESVIPDLKVYPGGQTIGVKVKSSGVLVVGHHIIQESNDRKVSPGETAGIRLGDRI
                     THMNGKPLNSLARVAEVVDEAGKNKKALDITLCRGEQTISTKLTPAYDQDDKAWRLGLY
                     IRDSAAGVGTLTFYAPDQGVYGALGHVITDMNTQTPIVVGSGEIVQSNVTSIAKSQSGE
                     PGEKRAHFLKDHRVLGNIERNTNFGIFGKMSDEPQYGLYSTPIPVALANEVKEGPAEIL
                     TVLEGQQIQRFQAEIVHISQQDKPATKGLVIRIVDPKLLDKTGGIVQGMSGSPIIQNGK
                     LIGAVTHVFVNDPKSGYGCFIEWMLRDAGIMQNNVSLKSSSNLKAS"
     misc_feature    18023..18038
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     misc_feature    18108..18123
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.78"
                     /tool="antismash"
     misc_feature    18175..18193
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.4"
                     /tool="antismash"
     misc_feature    complement(18179..18197)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.51"
                     /tool="antismash"
     gene            18234..19037
                     /gene="spo0A"
                     /locus_tag="JYU28_RS21045"
                     /old_locus_tag="JYU28_21085"
     CDS             18234..19037
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /GO_process="GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345656.1"
                     /locus_tag="JYU28_RS21045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21085"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_029517271.1"
                     /transl_table=11
                     /translation="MQKIEVLLADDNREFTNLLAEYISDQEDMEVTGIAYNGEEVLQRI
                     AESRNIPDVLILDIIMPHLDGLGVLERLREMNLTPQPKIIMLTAFGQENITQRAVQLGA
                     SYYILKPFDMEVLANRVRQLVGPQLVNSSPVTISSMRSNVVPMGKTKNLDASITAIIHE
                     IGVPAHIKGYQYLREAITMVYNNIEILGAITKTLYPAIAEKFKTTASRVERAIRHAIEV
                     AWTRGNIDSISHLFGYTINISKSKPTNSEFIAMVADKLRIENKVS"
     misc_feature    19217..19230
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.84"
                     /tool="antismash"
     gene            19418..20167
                     /locus_tag="JYU28_RS21050"
                     /old_locus_tag="JYU28_21090"
     CDS             19418..20167
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371761.1"
                     /locus_tag="JYU28_RS21050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_21090"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_069012723.1"
                     /transl_table=11
                     /translation="MNSIEYKEFYDKIGKINGWDFSKVKCISKGVKWDFYNEVAKTCKK
                     SDILLDIGTGGGEAILSIADSALLLVGIDHSTGMIETATKNSAESDIANVRFLQMGAEN
                     LNFPENFFNVISSRHSCFYAKEIEKVLVKGGMFLTQQVSENDKLNIKEAFGRGQAWGAK
                     KDSLKAKYITELSDAGFNDIQSFEFNATEYYQTPADLIFLLKYTPIIPNFGEKEIDFQI
                     LQQFILENQTEIGIRTNSERFMVIARK"
     misc_feature    20179..20194
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.72"
                     /tool="antismash"
     misc_feature    20179..20195
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 25.73"
                     /tool="antismash"
ORIGIN
        1 gtgcctcggc tgcgttcctc tttgcagata atacaccgac aaacgaatgg atcagacagc
       61 aggcggagca aatgcccaaa gacgaagtag aacattattg ggacgggctc atgcagcaat
      121 acggcggatt tttccctgat cagaaaacgc cttccttcat ggacatgctg cttccaggcg
      181 gtgaagggtt cagcataaag ggtgtattga gcgctatagc tgattttttc atccatgaaa
      241 tccgagtaaa tgccaagttg ctcgtcacca tcgtcatgct cagcattatg agtatggtgc
      301 tggaaacgct gcaaagcgct tttgaaagca aacaggtcag caaagtggcc tacgctatcg
      361 tatacatggt cattatcatt ttggcgatta atagctttag tgtagcgatt ggttatgcca
      421 aagaagcgat tgatagcatg attcacttca tgatggcaat gttgcctttg ctgtttacca
      481 tgctagcctc gatggggaac gtcgtaacag tttcggtgac ccacccgctg attgtattta
      541 tgatcaacac agtcggaaca gtcattcata cgctggtttt cccgctgctg ttcttctcgg
      601 ctgtgctgta tttggtcaac tcgctgacgg gcaaatacaa gctgacccag ctagccgatc
      661 tgttgcggaa cgctggagta gcagtgctgg gagtgctgct gacgattttt cttggagtca
      721 tttcggtaca aggcttgaca tcgtccgtta ctgacggatt aacgatccgt acagccaaat
      781 atattacagg tagctttgtt ccggtggtcg gcaaggcgtt ggcagatgcg acagatacag
      841 ttatttcggc ttcgctgctc gttaaaaatg ccattggtct ggtaggagtc attattattt
      901 tgttcctgtg cgcctttccc gccctcaaga ttctgacgct ggcgctcatt tataaagtga
      961 cagcagcgat catgcagcct ttgggtgata cgcctatcgt ggcatgtctg gatgcgatcg
     1021 gcaagagcat gatttatgtt ttcgcggcgc tggcagcagt gggattgatg tccttccttg
     1081 caattacagt catgctcgca gcaggcaata tgacagtcat gatgaggtga accaatgcac
     1141 gtaaaccaac aaggggggag gagagtgacg tgacctggct ggcaggctgg ctcaaggaac
     1201 tggtgctaat cgtgttgctg gcttcttttg tcgatatgat cttaccgagc cgatctatgg
     1261 agaggtatgt caaactcgtt ctcagcctgc ttattctgct gacgttgctg tctccggtcg
     1321 tgcgcttact gagtaccagt ccttccgagg ttctagggcg agcattggat cttcaacgtc
     1381 aggctgagac aggcaagagg gaaccgacat tggaggagat tctagcaaaa ggcagccagt
     1441 taaagctaca gcaagaacaa agctccatgc aatgggctgg caaagaggta gctaaggaaa
     1501 tgaaaggaca gttggaacag tatactgggt tagcaattca gtcggtccag gttacccttg
     1561 caaagattca acaggaggaa tcagggctgg aggcaggaac gggtgtccag tcggtagtgg
     1621 tccaattggc agaacagcag ccagaaaaag aaaagaaaaa cacagacgtc tcgcctggtg
     1681 cagatgtcaa gccgattatg gtggagcctg taaccgaaaa gacagtgaat attcgtgtag
     1741 agccaacaca tgcaaaaact tcagatttta atgaaggaac gcgagagaat gatcgtaatc
     1801 ctgacaaaac tgttgaggac ggaaagccaa cagatacgaa agcatttggc ttaattacag
     1861 gacttttacg tgaaaaatgg gggatagata gcaaaaatgt tcaggtgctt tcttcgcagg
     1921 atggaacaca tgaatggtaa caggaggtga gcagaaatga gcaaatggct gaaaaagctg
     1981 gagcaatggc tgggtggagg ggcggatggg gcgaaaaggt tcaattcatt tcgttggttg
     2041 cttattcttg gccttatcgg tgtagcgatt atgctcttta attcattcgt taatgtaaaa
     2101 aaggttgatc cagaaaacgt agggcgtgag ccgcctggcg tgatgaaaaa tgagcctacg
     2161 ttagagacaa caacaggtga agaaagttct tttgccggga ttgagaaggt ttttgaggac
     2221 aatatgaaac agatgctgga gcagattgtt ggcgtaggaa ccgttgatgt catggttacg
     2281 gtagactcca ccgaagaagt tatcgttcaa cgcaatgtaa aggacatgca ggaagagaac
     2341 aatgagacgg acgccaatgg tggacaacgg cacactactc aatatacacg tgatggcgaa
     2401 attgtcacct atgaatcatc tggtggtcag cacaccccga ttgtgacaaa aaaagtaaaa
     2461 ccgcaggtga ggggagtgct tgttgtggct atgggggcag aaaaccctac agtgaagcag
     2521 ctaattgtcg atgctgtaca gaaggggcta aatgtacctt cctacaaaat ttcagtcgta
     2581 ccgcgcaagc agggataatt tggaattcag gaacaaagaa gtttatattt taaaccatta
     2641 atgaatatgg aggacggaac atgaataata aaagacaaac cgtttggctg gtgtccatgc
     2701 tgagtttaat ggtcgtgctg tctgcgtatt atttgtttac ggaggactca agccctgcaa
     2761 atccaccagt agccgatagt gaacaagtga gcaaggttaa gcaggatgcc gcacaggaag
     2821 caacgacgaa ggcagaggaa caattgaacg aactgaaggt aaacgaagta gtgacgaatg
     2881 gagaagtaac tgatggagca tcagcaaatt ccacaaagtc ggatacggct tctacaactg
     2941 acccagcaac agaaaactca aaaggcgaca aaggtacggc agctacccct actactgaac
     3001 cggcgacatc caatcaaaac acaacagcga ctaagacgga cgcgacagca caaaatgacg
     3061 acaaagcagc ctctacagcc aaaaccgacc agcaggtact ggatcaagtg gcaactgatc
     3121 aagctgccca acctacagca gcagctgtga ttgacaacta tttgctggaa cgggacgtgg
     3181 aaaatcagaa gaaaaatgat gaactgacta ccgcaatgaa cgacagcaca ccaaagaaag
     3241 ctgcggaggc tcaaaaggaa ttacatgtac ttgaagataa gcaggctaaa attactggaa
     3301 ttgaagaaga gcttcagcaa cagttcgcca atgcggtcgt ccgtgaggaa gacgctgata
     3361 aatacaaagt agtggttctg agtgaaaaat tggatgctaa gcaagcggta acaattgtcg
     3421 acaaagtcat gaaggaactg aatgtaacgc aggataagat cagtgtccaa tatgttacac
     3481 aataagacaa aaaacgcgaa aaagcccgga tttctgcatt attccgggct ctttctattt
     3541 ttaatgattg tgatataata cataaagctg tttcaacaat gttatcagca accggcaaaa
     3601 tgctgaagga gtgattaata gagatgttta aattaagcga gattaaggaa ttgatcaagc
     3661 tggtggatga aacgtctgtg catgagcttg aaattgaaaa tgaaggaact cgcttgttga
     3721 tccggaaacc gggcaaaagc gaaatcgtta cagtacaggc tcctgtggca acacctgctt
     3781 atgcagtggc accacaagct gttattccaa atccacaagt acagtccgat gttggatcta
     3841 caactgctgg agaaccgagg gaatatgcaa gcaatctaca taaaatcgta tctccgatgg
     3901 taggcacttt ctatagttct tcatcaccgg atacggctcc gtatgtgagt atcggcagca
     3961 aagtgggcga aaaaacaacg gtatgtatca ttgaagcgat gaagctgatg aacgagctgg
     4021 aagctgaagt gaagggcgaa attgtggaaa ttttggccga aaacggacag ttggtcgagt
     4081 atggccagcc attgttcctt gtgaaaccgg agtaaaaagc ttgtttgcac cctcttttga
     4141 gggttcggca agactgctcc cagggaggat aaagtcatga catttcaaaa agtattgatt
     4201 gcgaatcgtg gagaaattgc ggttcgtatc attcgcgctt gccgcgaaat gaatatttcg
     4261 acagttgctg tatattcgga agctgacaag gattcgttac atgtgcgtct cgcagatgag
     4321 gcttactgta tcggaccgac gctatctaag gacagctacc ttaattttac gaatctgatg
     4381 agcgttgcta cattgactga atgtgatgcc attcatccag gttacggatt tttggcggaa
     4441 aacgcagact tcgctgaaat ttgcgaatcg tgtaatatta cgtttattgg tccttctcct
     4501 gaagccatta acaaaatggg agataaggcc gtagctaagc agaccatgaa ggatgccgga
     4561 gttccagtta ttccgggttc agacgggctg gttgaggatt tgcaggatgc gatcggcatc
     4621 gcacgtgata tcggatatcc ggtaattatc aaggccacag caggaggcgg aggtaaaggt
     4681 attcgtatcg ccgaagatga ggataacctc attcagcaaa tcactaccgc tcagcaggag
     4741 gcgcaaaaag catttggcaa tgcgggtgtg tacctagaaa aatatttgac cggtatgaaa
     4801 catgtggaaa tacagatcat agcggacaag catggtaatg ttgcccattt gggcgaacgg
     4861 gactgctctg tgcagcgtcg tcgtcagaag ttgttggagg aagcaccatg tcctgtactt
     4921 tcgcaggatg tccgtgaaga aatgggtcag gcagctgttc gtgcagcttt ggccgttcaa
     4981 tactctggtg caggtactct cgaatttttg ctcggcccgg acaacaattt ctatttcatg
     5041 gaaatgaata cacgtattca ggtagaacat cccgtaacag aaatgattac tggtgtagac
     5101 ctgattaagg aaatgatttc tgtcgctgaa gggcatccgc tttcctttac gcaggaagaa
     5161 gtcaccatca atggttgggc gatagagtgc cgtattaacg ctgaggatcc ggatcgtaat
     5221 tttatgcctg caccgggtaa aatcggattt tatctgcctc caggcggtcc tggggtacgg
     5281 gtagacagtg cagtatatcc aggttatagc attcctcctt attatgactc tatgatcgcc
     5341 aagctgattg tgtgggcacc tacacggcag gatgcaattg ccaaaatgaa gcgggctttg
     5401 actgagtttg ctattgaggg catacccaca acgatttctt ttcatcagcg cttgctagag
     5461 catccgacct ttattaaagg cgattttgat attaaatttt tggaggaaaa cgaagtttaa
     5521 tcggtatatt tcctccgttt gtcataatga acgccaaatg atatagtatg gataataagt
     5581 gagcatgtct gctttgaaat ctaaagctgg aatgaaactt attttgaccg aaaggtgttg
     5641 aaggtatgag cacagtgcca accgaattcg aacgtacaga aattggggag attcaaattg
     5701 ccccagaagt tattgaagtc attgccggac tggctaccgt tgaggtaccg ggcgtggcgg
     5761 gaatgagtgg cggatttgct ggtgggtttg ccgaactgct aggccgcaaa aatttatcta
     5821 aaggtgtaaa agtggaagtc ggacagcgtg aagctgctgt agacgtctcc gtcattattg
     5881 agtacggtaa ccgtctgcct gaggtggctg ctgctattca gcataatgtt aagcgttcga
     5941 ttgagaacat gacaggtctt aacgttgttg aagtgaacgt gcaaattcat gatgttcaat
     6001 tcaaaaatgc cgataaagta gaagagccgg aagtgctggg cgccggacgg gttaaataga
     6061 gcgatacttt gtacaaaccc ccgaccctta tgggtcgagg gtttactcta atttaaggag
     6121 gctgtgcgtt tcgtggctaa agttatggac agacttctgc tgttcttgta cagcttaagt
     6181 atcggaatta tttccattct cgctatcctc ctcctgagcg gggccattcc gtatgtttta
     6241 agtattgagg atgagcgagt agtgtggttt accagcctga ttattgcagg ggttctgttg
     6301 ttattgagtc ttcgtttttt ttatatctct attcgacgga accaaaccgt acagcattct
     6361 attgatcaac gaacggaata cggtgacatt cagatttcag tggataccat tgaaaatctg
     6421 tgcctcaaag cagcttcccg atttcgcggg atgcaggatt tgaaagcacg cgttcgtgtg
     6481 ttggattcgg gacttgatat tacgattcgg gcggttgtag acggggaaag ctccattccg
     6541 gtgttaacct ccgaggtaca aaagggggta cacgatcatg tggaagaaat tacaggaatt
     6601 cctgtgtcca atgtatcggt gtacatcgct aatgtttctc agtcacccag ctttaagagt
     6661 cgtgtggaat agaggtgatt ttccctgatg ccctggaaag aaatatgggg aagttacaag
     6721 ggccggatca tggggatcac ggctggtatt tttttcggtt ttatttattt gtgggcaggc
     6781 ttttggaata tgttgttctt tgcattgatg gtgttcatcg gatatacgct aggaagacgt
     6841 agcgattcag cgctcggttc attcctccct tggaaggaat ggggcgattg gttgtcgcaa
     6901 cgttggcgtc cttttaaatg aaccctgtga tacgtgttct ccaaaaatag agctgtagct
     6961 tctttgcgcc caacgttttg gaggatgcgt tcacaggttt ttttgtggaa attggttaga
     7021 atgaaaaata gatataggca agcgtaggag gcagggcatg aaaagacgtc tggcgaggga
     7081 attagcggta cagagtatgt accatatgga aatgaatgaa gtggatgcgg cagcagccgt
     7141 ggacatgttg cttcaggaag ccgctgagga aaacgaagcg gaagttgtcg ttaaaaatgc
     7201 agcagtgtta agagcgtatg tcttggagca tgtgcggggt acgtgggagc acaaggaagc
     7261 cattgatggg ctgctggtgg attatcttaa aggctggcag atcagcaggc tttcacgtgt
     7321 agatcgtcaa attttaaggc ttgcggcata tgagatgatt ttccgtgagg atgttccagc
     7381 caaggtagct gttaatgaag cgattgagtt gtcgaagcac tttggtaccg aggaatccgg
     7441 taaatttgtt aatggcgtac tggggcgagt gatacaagaa ctggagcaat tgaaagcacg
     7501 tttttaagta gagactactg aatcaggttg gagagtggta aaacatgtca gcaccgatca
     7561 ttgatggtaa acaaatctct caggatattc gcgcaagcat tcagcaagag gtcattcgtt
     7621 tgaaagagca cagctttcaa cccggactgg ctgttgtatt ggtaggcgaa gatcccgctt
     7681 cgcaagtgta tgttaaaaac aaggaaaagg catgccatga tctcggctat tactccgagg
     7741 ttcaccggtt ggcagcagat acttcgcagg aagcattact ggaactggta aacaagctga
     7801 accatcaaag taccatccat ggaattttgg tgcaactgcc gttgccaaag catattcatg
     7861 aaaaagctgt cattgacgcg attgcagtgg agaaggatgt ggatggattc catccggtga
     7921 acgtagggaa tttggtcatc ggtgacgata gtctattgcc ttgtactcct gctggagtca
     7981 ttgagttaat taagcgtgct ggagtggaga tagccggtaa acatgcggta gttattggtc
     8041 gcagtaatat cgtgggcaag ccagtgtctt tattgttgca gcgtgaaaat gctacggtta
     8101 cgatgtgcca ctcccgtaca gcgaatattg cggacctaag tcgacaagca gatatcttag
     8161 tcgttgcgat cggcaaagcc aactttattg atgcttcgtt cgtgaagccc ggagcggtag
     8221 tgatagatgt agggatgaac cgtctggaaa acggaaagct ggcgggggac gttgattttg
     8281 agagcgtgaa gcaagtgtct ggtccgatta cgcctgttcc cggcggagta gggccgatga
     8341 caattacgat gctgatgcaa aatacgctcg tagcggccaa gcggtcgcac ggtttggcat
     8401 aaggacagct gcctgtggct gaacaacgta tttactctat aaaggacctg aatcgttata
     8461 tccggatgaa attggagtcg gatcaggtgc tgtctgatgt atggatacgc ggggaaattt
     8521 ctaattttac gcatcattca agtggtcaca tgtactttac gctcaaggat gaggggagcc
     8581 gcatacgttc gattatgttt gcaacccata atcagcggct ccctttcgta ccgaaagaag
     8641 gtacgcgtgt tattgcccgg ggaaacgtat ccgtgtacga acgagatgga caatatcagt
     8701 tttatgcgac tcaaatgcag cctgatggta taggaagcct ttatttagct tacgagcagc
     8761 tcaagcaaaa gctggatgca gagggactgt ttgatactgc tcgtaagcgt agcctccctg
     8821 cccatccagt aaccattggc gtgattacgt caccgactgg agcggctgtg cgtgatatta
     8881 ttacgacact tcaacggcga tacccgcagg ctggaattgt gttgtatcct gtgcttgtac
     8941 aaggaaaagg tgccgccccc tcgatcgtca aggcaattga aactatgaat cgtatgcaag
     9001 aggttcaggt gatgattgtc ggacggggag gtggctcgtt ggaagaactg tgggcgttta
     9061 atgaggaagc ggttgcgcgc gccatttacg catcggtcat tccagttatt tcggcagttg
     9121 gacacgaaac ggattttacc attgccgatt ttgtggctga cttacgtgcg gcaacgccaa
     9181 ccgcagcagc cgagttggcc gtgcctaatc aggcagagct acgggatcag ctgctccagc
     9241 gggagcaacg gttgcgtaac gccctccggc agcggctgga aaccagccgt gtacgcttgg
     9301 cgaggcttca gcgttcacca gtcctgctgc acccacgccg ctatatgcta cagcatgcag
     9361 agcgaatgga catgctgcat cagcgtctaa tccgcgcagc gcgtaaccgt tctcgtttga
     9421 acgcagaaaa gaacgcacgt atgcgtcagg tactagaacg gtttaatccg cgtgaacaaa
     9481 ttcgttcagc acgcaagcag acggatatgg cgcaacgtca gctggagtct gcgatgcgtg
     9541 ctattacgaa aacgggacgg cagcagttgc acacgggaat tcgtcaactg gatgcgctga
     9601 gcccactcaa agtcatggcc cgaggctata gcttggtata cgatgagcag gaaaaacggc
     9661 tgattaagtc gctcaaagac gtacagccgg gagattccat caagattaaa gtgagtgatg
     9721 ggcagttgga ctgccaagta tggggaatga aggaggacgc gaagcacggt ggcgaatgaa
     9781 acggaattga attttgaagc ggctatggct gctcttgaag aaattgtcgg acaactggag
     9841 catggagacg ttcctctgga gcaagccatt gatttgttcc agcgggggat gaagttgtct
     9901 caactttgca gtcagaagct ggagcaggtt gaacgtaaaa ttgaaatgat cgtggaagag
     9961 gatggagatt tgcgcaagaa gccttttggt gggggactgg atgaaaacgg cggtgaagga
    10021 cttgaataga ccgtcgttca aggaatattt gaccgggacg acggatgcgg tttcgtccgc
    10081 actgaccgag caattcccgg ccgattggga cattcccgat gttcttcgag aatccatgaa
    10141 ttattcactc accgcaggcg gaaaacggct gcggcctctg cttgtgatcg ctgctgctga
    10201 agcattcggt ggaagcaggg aagctgcgct gccagtggca tgtgcggtag aaatggtaca
    10261 tacgtactcc ctcattcatg acgacttgcc agccatggat gatgatgact atcggcgagg
    10321 taagctgacg aatcataagg tatacggcga ggcggttgcc gtccttgcgg gtgatgcttt
    10381 gttgacccat gccttttaca gtattgtgca agcaggacgg cgtcacggtg tttcgtctga
    10441 ttcgctattg tccatagttg aggatttgtc cgaaatgagt ggcgcgcggg gcatggtagg
    10501 cggacaggtc gccgatatgt caggcgagca aggaatgacg gggatcgagg aactggaata
    10561 tatccatctt cataaaacgg ctgatttgat tattttctcg ctcttggcag gtggacggat
    10621 tggtggggcg gacaagggtc aattagaggc gcttcgacgc tttggacgag atttggggct
    10681 ggcttttcag atacaggacg atatactgga cctcataggc gatgagagta aaatgggtaa
    10741 gaaaacgcaa agtgatgttg aacaagagaa ggtcacctat ccgtatttca ttggtatgga
    10801 cgcatctttg cagcaggtag aggaactcac cgcatctgct aaaagagtga taatagagag
    10861 tggtatcccc gattcttctc gtttgctgga gatagccgat tacctgatga agcgtgatca
    10921 ttagttgcgt tagagctgtt ttgacttgtc tgcgtttaag cacagtcaaa aagtgtgata
    10981 taatacttgt taactttact cacaaacttg aaggaaagcg gggagatatg cgtgctgctt
    11041 ccacacataa agcaaccagg cgatctgaaa tcactgtcgg ttgaggagtt ggcttctcta
    11101 gccgaggaaa tcaggagctt tttgattgag aagctgtccg tgactggggg gcatctggca
    11161 tcgaatctgg gagtggttga gctcacgatc gccctgcatt attgctataa cagtccgaag
    11221 gacaagatga tttatgacgt tgggcaccaa gcctacgtac acaaaatatt gacagggcga
    11281 atggaccgtt ttgatacact tcgtcagcgt gatggacttt gtggttttgt aaaaagaagt
    11341 gagagcgagc atgatgtttg ggaagccggt catagcagca cttctctgtc ggccgcaatg
    11401 ggaatggctt tggctcgaga tttgaagggc gaggacaata aagtcattgc aatgatcgga
    11461 gacggcgcgc tgactggggg gatggccttc gaagcgttga atcatatcgg acatgagcgc
    11521 aaaaatttaa tggtaattct gaatgacaac gaaatgtcca tagcacctaa tgtaggggcc
    11581 atgcataatt atttgagtaa aatccgctcg gaccgccatt atttgcgggc aaaagatgag
    11641 ctggaagttt tgctgaaaaa aatacccgcg atcggcggta aacttgccaa atcggctggc
    11701 cgtgtcaagg acagtcttaa atatatgatg gtgcctggtg tactgtttga agagctggga
    11761 cttacgtatc tcggtccagt ggacggacat gatttgccga agctaatcga aaccttccag
    11821 caggctgata atgtcactgg ccctgtattg gtgcatgtcg taaccaccaa gggcaagggc
    11881 tataaacctg cggaagcaga ttcacacaaa tggcatggaa tcagtcccta caaaattgaa
    11941 tcgggtcagg tactcaaagc tgtaggtaat ccgatgtata cggaaatttt cggtcgaacg
    12001 ttgattgagc tggctgagca ggatgagcgc atcgttgcgg tcacacccgc tatgcctggc
    12061 ggatcaggtt tggtaccgtt tagtaaagag tttcctagcc gtatgattga cgtcggcatt
    12121 gctgaacagc atgcagctac catgtgtgct gcgttggcaa tggaagggat gaagccggtg
    12181 tttgcggtgt actccacttt tatgcagcgt gcttatgacc agattgtgca tgatatctgt
    12241 cgtcataatg cgaacgtaat gttcgcgatt gaccgtgcag gttttgttgg ggctgacggg
    12301 gaaactcatc atggcgtgtt tgatgtggca ttcttacgtc atatccccaa tcttgtgctt
    12361 atgatgccaa aggatgagaa cgagctacgt catatgatga aaacagcgct cgactatgaa
    12421 gatggtccaa ttgcttatcg ttacccacgt gttaatgtgg ttggcgtgcc gttggataaa
    12481 gaattacagg ctattcccat cggcagttgg gagctcctgc gtaagggtga gggctttgct
    12541 gtaattgcat caggaccgat gctccaggtg gcgacagagg ctgcggaggc gatgaaacgg
    12601 gaaggtttgc aagtgggcgt cgtgaatgct cgtttcctga aacctttgga cgaggatatg
    12661 ttgcgtgagc tggctcgtca gcatacgaag ctgatcgtat tggaagaagc ttctgaagca
    12721 ggaagcttgg gtagcgctgt actggaattt tacgctaaag ccgaaataca agaggcacag
    12781 gtgcgcctaa tggggattcc cgatctgttc gtggagcatg gctccatcaa agagcagcgt
    12841 gctgaagtag gtctcaccat tgaagatgta tgcttaaagt tgcgtaaatg ggctgctgag
    12901 ccagcatatg gcatgggaca atctgtatag ggtaacttga agtgaagacc atgacgttta
    12961 taaaaagtat gacaagagca gcctggctgc ctaaagggag attaacatgt ctgttccgaa
    13021 ggaacgcatt gatgtattac ttgtagaaca aggctttttt gaaagccgtg aaaaagctaa
    13081 agctgcgatt atggctgggc tagtgctggc ggacagcgaa cggatcgaga aggcggggat
    13141 gaaggtacca cgcgccagcg agcttaaagt taagggttcg gtgcatccgt atgtaagccg
    13201 tggaggattg aagctggaga aggccatccg tcaatttgag ctggatatga agggcaggac
    13261 aatgctggat attggctcgt ccactggagg ttttacggat tgtgcgcttc agcatggagc
    13321 tgaatacgta tacgccattg atgtgggtta taaccagctg gattggtcgc ttcgtaatga
    13381 tgaacgagta tgcgtaatgg agaaaacgaa tttcagatat atgacacccg cggatttgaa
    13441 tggttccgtg ccgaattttg ctagtattga cgtttccttt atttcattac gtattatttt
    13501 gcccccgttg cttgccttgt tgcatcaacc tgctgatatt gtagctctaa tcaagccgca
    13561 attcgaagct ggacgcgaaa aggtcggaaa atccggtgtg gtccgtgatc ctgctacgca
    13621 taaagaagtg ttgcagacca ttctgatgtt tgcacatgag cttggactta cgctgcaagg
    13681 tttggcttat tcacctatta caggtggaga aggcaatatt gaatttttag cgcattggcg
    13741 tttggatggg tttcctgctg cagaatcgca gctggagaag atggatttca gaccactgat
    13801 tgaacgtacc gttcaggaag caggtcagac ttttaataat ggtccatcgc gtaagtaaca
    13861 ttcaggggtt ctccatgagt tctgtgaact taagggaacc tctttttggt gtgagggatt
    13921 gattatagaa ctcacgttcg cctataatga gatgtacaaa ggaaaaggga ttttacatct
    13981 tgtcctagaa tatgtccatg aggtgatcgg tccatggaca caagatatga tacggttatc
    14041 atcgctgtga tcggggtgat attaggaata tgggctttgt atagcctacg tgcctggttg
    14101 aaggagccag agccgcttgt gctaaagacg ataccgatta acgaggactt ggacgaagga
    14161 cctgccacac acctactcga agaagcagga tatgaagtag tgggcgggaa gatgaaaata
    14221 ccgcttgctt ttaaagtgaa cggacatacc gtgtatagcc gtttgtttat agactacgtg
    14281 gctgtacgaa acggttcgac atatatggtc aaaacgtcac gccgcaagaa accaatggag
    14341 tggagtggtc ctgatttaag ggacaggctc atgccgtatt tattgctcta tccgggttgc
    14401 gcgggtgtat tgtacgttga tacggacgag cgaagtattc gccttattac attagtggaa
    14461 gacctcgaag aagaggaata tgaaggttaa tccataggag gattatatga agggtcaacg
    14521 acatattaaa attagggaaa ttatttcaca acatgagatt gagacgcagg atgatctggt
    14581 tgaagcattg cgtaaggctg gttttcaggt cacgcaggcg accgtatcgc gtgatatcaa
    14641 ggagctactg ctcatcaagg tcccaatgga cgatggcaga tataaatatt cgatgccttc
    14701 agatcagcgc tacaatccag cccagaaact gaaacgtacg ttggttgata actttttgca
    14761 tattgactac acaaccaatc tgattgtgat gaagtgtctg ccgggaacag ccaactcgat
    14821 tgctgcttta ttggacaata ttgaatggtc cgaaattatg ggtacgatta gcggagatga
    14881 caccattttg attatttgcc gatcggaaga aaacagcgaa gctatcgtga atcgtcttat
    14941 gggctacatt tcctaattat aatggctacg catattaggc gttttaattt gtacatcata
    15001 gaggtgaaag aacgatgctg gtcactttgt ctatacggaa tttggcggtc gtagaggccg
    15061 tcgatgttca tttttataaa gggtttcatg tgttgagcgg ggaaacaggt gctggtaaat
    15121 ccattattat cgatgcgctt gggctaattg caggcggtag gggctctgct gatttagtgc
    15181 gttacggttg tgataaagca gagatggaag ccttgtttga actgccagta aaacaccccg
    15241 tttggaatac acttgaggaa caagggatta aggctaatgc ggaggagcat ttgctaattc
    15301 gtcgtgaact tacggttcag ggaaaaagct cttctcgaat taacggccag atggttaatt
    15361 taacgatgct gcgtgaggta ggtgagcaac tcgtcaatat acacgggcag catgagcatc
    15421 aaagcctgct acgtgcagat cgccatctgg cgctgctgga tacgttcggt gattcggtga
    15481 tcggtccggt caaaacgctt tatcgggagc gttacaatgc ttttgtcaaa gcggaaaaag
    15541 aagtaagaga actgcaaagc tccagtcaaa aggcttatca gcttttggat atgtaccgat
    15601 ttcaactaga agagatcgct gcggcggagt tgaaattggg agaagatgaa ttattggcag
    15661 aagaacgggt caagctatcc catagtgaga aaatgatgga tgggatatca ggagcatacg
    15721 aactcttaag cggcagaggt ggactggata cgatcaataa cgtgttgacc agattgaacg
    15781 atgtccaaaa ctatgacagc aaaagccttc agcccattgc agagcagatt cagtctgctt
    15841 tttaccagtt ggaggacgca gcattccaat tacgttctta tcgtgaggat attgaattta
    15901 atccaggcaa gctgcatgaa gtggaacaac gtttgaatca aattaccgga ttacagcgaa
    15961 aatatggtga tagtatagag cagattttgg aatactatag ccgtattgag caggaaaccg
    16021 atctgctgga aaataaagat gagcggctgg agcagctcat tgcaaaacgg gacgagttgc
    16081 tgtccgattt gcttgagatt tcggaagagc ttacagaagc acgtgaaatt tgcgctgaag
    16141 agcttgcaga gcaagtggag caggagttaa aagacctaca gatggaaaga acgtcactca
    16201 aggtgcgcat tgatccaatt gaagatccac gcggatatga gtacaaaggt ctgaaggtaa
    16261 gacctaccaa gcagggcatt gataatgctg aatttcttat ttcccctaat ccaggtgagc
    16321 cattacgtcc acttggtaag atcgcttcag gcggtgagct atcacgtatc atgttggcga
    16381 tgaaaagtat ttttgcgcgt catgatcaaa ttccagtact catttttgac gaggtggata
    16441 ccggggtgag tggtcgtgca gctcaatcca ttgccgagaa gctatatcgt ttatcttccg
    16501 tttgtcaggt gttctccatt actcatttgc cacaggtggc atgtatggca gatcatcagt
    16561 accttattga gaaaaatgtt catgacggac ggaccatgac tcaaattgag ggacttacgg
    16621 aggacgggcg tgtcaaagaa ttggcacgga tgctgggcgg tgtggaaatt accgaaaaaa
    16681 cattgcatca cgcacaggaa atgctgaatt tggcggaagg aaagaaagcc tgaaaagagc
    16741 ggccggcgta atgtttaaca gttataaaag cctgggggca aggttacctt ataggtacgc
    16801 aattggcgac cacctttact cgtcaagcga aagaagcaaa gggagcgtga cagccattga
    16861 atttttactc caggatcaaa ttgctcggtc ttttgcttgt ttttcttatg tgttctatcg
    16921 gtaacgctca gcatgtgcaa gcagcgctgc ctccacaagc ttctttggat ttgttcggtt
    16981 ctaaaagcgt gaggacaacc caagaaagtg taattcccga tttaaaagta tacccgggag
    17041 ggcagacgat tggggttaaa gtaaaatctt caggagtgct tgtcgtcggt caccatatca
    17101 ttcaggaaag taatgatcgt aaggtatcac ctggtgaaac agcggggatt cgcctagggg
    17161 atcggattac acacatgaac ggcaaaccac tcaatagcct ggcaagggtt gctgaagtag
    17221 tagacgaagc aggtaagaat aaaaaggcgc tcgacattac gctttgtcga ggtgagcaga
    17281 ccatttccac caagttaaca ccagcatatg atcaggatga taaagcatgg cggcttgggt
    17341 tgtatattag ggactcggct gcaggtgtag gtacattaac gttttacgca ccagaccaag
    17401 gtgtatacgg ggccttgggc cacgtaatta ccgatatgaa tacccaaacc cctattgtcg
    17461 tgggaagcgg agagattgtg cagtccaatg tgacatcaat tgcgaaaagc caaagtgggg
    17521 aaccaggaga aaaacgcgct cattttctca aagatcatcg ggtattagga aatattgaac
    17581 gaaatacgaa tttcggaatc tttgggaaaa tgtcagatga gccgcaatat ggattgtatt
    17641 cgactcctat tccggtggct cttgcgaatg aagtaaagga aggacctgca gaaattttga
    17701 ctgtactgga aggtcaacaa attcagcggt ttcaggcgga aattgtacac atttctcagc
    17761 aggacaaacc ggcaaccaaa ggacttgtga ttcgtattgt agatccaaag ctgttggata
    17821 agaccggggg aatcgtgcaa ggaatgagcg gtagtccgat catccaaaat ggtaagctta
    17881 tcggggctgt aacacatgta tttgtgaatg atcctaaatc aggttacggt tgttttatcg
    17941 aatggatgct gcgcgatgca ggaatcatgc agaataacgt aagcttaaaa tcatcttcta
    18001 atcttaaggc gagctagtgg ccttaagatt tttttgtcga aaagcagggg aatagctcat
    18061 aattgcaaga taaagaatca attataatag aaactataaa aaaaataaat aaaaataatt
    18121 ttcgacagaa ggaattcata attcgatgtc gaaatcatat actccgacaa gaaatattta
    18181 tatactgtaa acagatatca caatggaata tcactcaatg aggaggaagt acattgcaaa
    18241 aaattgaggt attgttggct gatgacaacc gggaatttac gaatttgctt gctgaatata
    18301 tttccgatca ggaggatatg gaagttacag gaatcgccta taacggcgaa gaagtgctcc
    18361 aacgcatcgc agaatcccgc aacatacctg atgtacttat tttggatatt attatgcctc
    18421 atctggatgg tctgggtgta ttggagcgtt tgagagaaat gaacctgact ccacagccga
    18481 aaatcattat gctgactgca ttcggtcaag aaaatattac acagagggcc gtacagctcg
    18541 gggcatctta ttatattttg aagccgtttg acatggaagt gctggctaac cgtgttcgcc
    18601 aattggtggg acctcagtta gttaacagca gtccggtgac catttcatcc atgcggtcca
    18661 acgttgtacc tatgggtaag acgaaaaacc tggatgccag tatcacggcc atcatacatg
    18721 aaattggtgt accagctcac atcaagggct atcaatattt acgtgaagcc attacgatgg
    18781 tgtacaataa tatcgaaatt ttaggagcca tcaccaaaac attatatccg gcaattgccg
    18841 aaaagttcaa aacgacggca tctcgcgtag aacgcgccat tcgtcatgct atcgaggtag
    18901 catggacccg cggaaatatc gacagcattt cacacctgtt cggttacacc attaatatca
    18961 gtaagtccaa accaaccaat tcagagttca tagcgatggt ggcagataag ctgagaattg
    19021 agaacaaggt gtcctgaaag ggccagaatg attgatgaag caaggaattc ttgggttttg
    19081 acgtttatca atgataattg tagggacggc tacgaatctc cacaacagcc gtcccgatac
    19141 cgatatactt ctgaatagtg gacaactaat accgcctttt tattggttct tccagacacc
    19201 agtaaaggag cggtattttt tataattaaa acaatctttc aaatgaggtg aatcggatgt
    19261 ctttccgtac tgttcgaagt atttagtttc cgggttggaa aaaaacgcgt accagccgtc
    19321 aaggggggag tctatccttt tgactaaaca aactaaaatt ttgaatatcg gtctgctagc
    19381 ccgtagcttt tatccttatt tggaaggtga aaagtaaatg aattcaatag agtataaaga
    19441 gttttatgat aagattggaa aaatcaacgg atgggatttc agtaaggtga aatgtatctc
    19501 caaaggcgta aaatgggact tctacaatga agtagcgaag acatgcaaga agtcggacat
    19561 attgcttgac atcggtactg gcggcgggga agccatttta tcaatagcag attctgcatt
    19621 acttctagtt gggattgacc attccaccgg aatgattgaa acagcaacca agaattctgc
    19681 tgaatcagac atagcaaatg ttcgttttct ccagatgggt gctgaaaatc taaattttcc
    19741 tgagaacttc tttaatgtaa tctcttctcg acactcatgt ttttatgcaa aagaaataga
    19801 aaaggtgtta gtaaagggtg gtatgttcct gacacagcaa gtaagcgaaa acgacaaatt
    19861 aaatattaaa gaagcgtttg gaagaggaca ggcatggggt gctaagaaag actcgttaaa
    19921 agctaaatat attacggaat taagtgatgc gggctttaac gacatacagt catttgaatt
    19981 caatgcaacc gaatattatc agactcctgc agacttaata tttctcttga aatacactcc
    20041 aattattcct aacttcggag aaaaagaaat tgattttcaa atactccaac aatttatttt
    20101 ggaaaaccaa accgaaatag gaataaggac aaattcagaa cgatttatgg tgattgctag
    20161 gaagtaaaac ataaagagat acccgttttg ggtatctttt ttttaaactt agaagtttga
    20221 tgcaataagt gaataaagat tttcagcacc tctcttgcta tatatgacgg tacaattgtt
    20281 gggaattata aaacataatg ctctacaaga ggtatataat ataaacctga atcagttgca
    20341 ctaactatca cgaagagaaa tctccctttt gtaaacagtt ctgaaattct ctttaaattt
    20401 gatataaaca atgtgtcgtt tcttgtcgat atagtatcta attataaaga gagctgagga
    20461 gcgaatatat gaaatttaac attcgaacaa aattgatatt aggttttctt gcggtaataa
    20521 tattattgat tgtcattagt acaacatcta tctccagaat gaaaaaatta ggtgacactt
    20581 cgatggcaat cgatagccat tggatgccaa gtgtgactat cctgggaaca ctaaatggtg
    20641 atatatctga cgtagagcgg atctcattaa acattattgt agaacgtgac ccagaagaaa
    20701 tggagaaggt tcaggcagaa tatgataagg ttttaaaaaa ggttgaggac ggtcgaaaaa
    20761 catacgaaaa attaattgct acccctaaag aacgtgaaat gtatgaagaa ttctccaaaa
    20821 attatgcgga gtatttggct aagttgccag aaatgattga agcggggaaa gctaatgatt
    20881 acactcaatc aagcatcctt catcaagagt cctataagtt atgg
//
