LOCUS       NZ_JAFJXZ010000012     24126 bp    DNA     linear   CON 03-JUN-2024
DEFINITION  Paenibacillus polymyxa strain Hob6 Scaffold_12, whole genome shotgun
            sequence.
ACCESSION   NZ_JAFJXZ010000012
VERSION     NZ_JAFJXZ010000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 1543484)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Draft genome sequence of Paenibacillus polymyxa strain Hob6,
            isolated from hemp (Cannabis sative) seeds' oil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1543484)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2021) Plant Science Departement, McGill
            University, 21111 Lakeshore, te-Anne-de-Bellevue, Quebec H9X 3V9,
            Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-JUL-2020
            Assembly Method                   :: SPAdes v. 3.12.0; Medusa v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly :: GCA_000507205.2; GCA_014706575.1;
            GCA_000164985.2; GCA_000597985.1; GCA_002893885.1
            Genome Coverage                   :: 266.29x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017589695.1-RS_2024_06_03
            Annotation Date                   :: 06/03/2024 02:57:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,275
            CDSs (total)                      :: 5,119
            Genes (coding)                    :: 5,024
            CDSs (with protein)               :: 5,024
            Genes (RNA)                       :: 156
            rRNAs                             :: 21, 9, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 19, 2 (5S, 16S)
            partial rRNAs                     :: 2, 7, 15 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 44 of 95
            Pseudo Genes (incomplete)         :: 63 of 95
            Pseudo Genes (internal stop)      :: 13 of 95
            Pseudo Genes (multiple problems)  :: 21 of 95
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 471750
            Orig. end                         :: 495876
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAFJXZ010000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24126
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="3"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24126
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24126
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14126](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14126
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(17..30)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    complement(133..149)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            238..1158
                     /locus_tag="JYU28_RS05155"
                     /old_locus_tag="JYU28_05175"
     CDS             238..1158
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821230.1"
                     /locus_tag="JYU28_RS05155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05175"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_029516218.1"
                     /transl_table=11
                     /translation="MQQATGQVPVIRMEGVSKIISSKAIVDDLTLEVPAGQVFGFLGPN
                     GAGKTTTIRMMVGLISISKGDIHICGDSINTDFEKAVSHVGAIVENPEMYKFLTGYQNL
                     QHFARMSPGVTQERVDEAIRLVGLGNRIHDKVKTYSLGMRQRLGVAQAILHRPKLLVLD
                     EPTNGLDPQGIRELRDYLRQLTRTEGITVFVSSHLLSEMELMCDRVAIIQSGRLVDIKQ
                     LKNTGEEVQTAEIAFEVNDAEQAYALAGAGRVEGNQLLLHLEREQIAEMNSLLAANGIK
                     VYAIRPVARTLEDQFLEVTGGGFIG"
     gene            1151..1933
                     /locus_tag="JYU28_RS05160"
                     /old_locus_tag="JYU28_05180"
     CDS             1151..1933
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369846.1"
                     /locus_tag="JYU28_RS05160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05180"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_029516219.1"
                     /transl_table=11
                     /translation="MGDFFKLVHNENLKIYLRVRTWIMLGLLAVITAAIPMLISLVSDQ
                     VSVWDGIALTTLFTFFLNTTFTVIVAADSVAGEFTWGTIKLLLIRPWTRSKILLSKYIS
                     VILFSLLGTIILILMVTLSSWLMLSKDAPAGSVPLFSDPISYVTLNFLYSYIALFVTMA
                     FAFMLSAVFRSSALAIGLSLFMMFTKTIYNSIGLFSTDRFEWTKYVLFTHMDLKKYLDM
                     PPGTVSSSLTFSLTVLAAYYVIFIAIAWVVFVKRDVST"
     misc_feature    2084..2100
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            2173..3258
                     /locus_tag="JYU28_RS05165"
                     /old_locus_tag="JYU28_05185"
     CDS             2173..3258
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426473.1"
                     /locus_tag="JYU28_RS05165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05185"
                     /product="AI-2E family transporter"
                     /protein_id="WP_029516220.1"
                     /transl_table=11
                     /translation="MLQNNRFFRVTTGIVMLLLIIYLGTKVSFIFSPLVSLVSLLVVPL
                     MLSFFLYYLLRPIVDVMERRKIKRSISILLIYLVIGVLLFVFSWGVWPTLRDQVTNLFE
                     NAPKLIKSLVDQLSQWRHNQSLRQVLPPGEDPLSQLSDTLNEAFSTLSDYSVKLVSFVS
                     YFFIVLATFPILLYYMLKEGSKFGPKMLNFFPKKYHKDALEVMEDIDSALSSFIVSRVL
                     INVALGVMMFLGFLIIGLPYALLLAVISIFLNFIPYVGAVAASIPVVIIGFLESPSMAL
                     WSLVVVIAAQQIQDNWLSPIVFGKQLDIHPLTVVILLLVGGDLLGILGIILVIPLYMCG
                     KIVIRKVYQLFLERRVEDIME"
     gene            complement(3298..3759)
                     /locus_tag="JYU28_RS05170"
                     /old_locus_tag="JYU28_05190"
     CDS             complement(3298..3759)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369848.1"
                     /locus_tag="JYU28_RS05170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05190"
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_029516221.1"
                     /transl_table=11
                     /translation="MFKESKKKLSTPAMDTLLANGTSFEGTVEAEANIRIDGHFQGDIR
                     STRTVVIGESAVVRSDIFAQDVILAGKVFGSITTEGRLTITPTGELYGNTATAALVISE
                     GGVLDGTSQMNRTKDVELSASTDEPNDETQSSFSKDREDSQATLQSEAG"
     misc_feature    3779..3793
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.16"
                     /tool="antismash"
     misc_feature    complement(3803..3821)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.46"
                     /tool="antismash"
     gene            complement(3805..4836)
                     /locus_tag="JYU28_RS05175"
                     /old_locus_tag="JYU28_05195"
     CDS             complement(3805..4836)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426474.1"
                     /locus_tag="JYU28_RS05175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05195"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_029516222.1"
                     /transl_table=11
                     /translation="MKKGSLNRRMTLLVIRDAQQPPKQLQCSTAAVILVPTLVIASIST
                     LVIGLQIRSSHIISQMETNLAVQSLQMEVTVADKDAAIGRLRQEVMELTNQATHIRERL
                     QRVTELEQQMQQFIRKHGNSSATSNHKKTMTPLSWDASGHIGGELIAVHENTAFLTRQA
                     MDDFQEIESLLDTVERTVPRSIQQANAVQQNLERKQAAQLLQTRRLALAVQGKPSVWPV
                     GSRRMTSSFGYRSDPFTGRSAFHSGVDIAGQTGDPVYAAGAGTVLEAASSGARGKCIII
                     QHPDGLQSWYMHLSGMQVAPGDRVHKGQTIGLLGSTGRSTGPHLHFQIVKHNQPVDPLL
                     YVQ"
     gene            4983..6413
                     /gene="cls"
                     /locus_tag="JYU28_RS05180"
                     /old_locus_tag="JYU28_05200"
     CDS             4983..6413
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686424.1"
                     /locus_tag="JYU28_RS05180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05200"
                     /product="cardiolipin synthase"
                     /protein_id="WP_029516223.1"
                     /transl_table=11
                     /translation="MLWLLLVLIVFIFQTGTILLFEFRKPSKAVAWLFILFCFPLIGFV
                     VYYFVAQDYQKRKVVRKGGSQLFREFRERLWAQSKVIEHVEQMHNPHFKHQERLFNQLI
                     RMSENPLTGCNRTRVLTNGEEAFEAMLAAMEHAQHHIHVEFYIFRADEIGRKFQEVMIR
                     KAREGVKVRFVVDGVGSYNLPYSFIRTCSEAGVEFHYFLPPFFATLDRRINYRNHRKIV
                     VVDGMVGFVGGINVGDDYLGKYPKVGFWRDTHLQIEGDSVYFLQNAFLSDWKLASGERL
                     MDVNLFPPHTCTGDEEVQILSSGPDQVWDTIQEMCFGALTVAKKRIWITTPYFIPDPGI
                     YEALKLAAVSGVDVKIIIPYQSDSKLVHLASLSYVQELLEAGVEFYQYRKGFIHAKVVI
                     VDDLLGSVGTANMDMRSFFYNFELTAVVFANSALERLSADFVEDISNSSRIDLNVFRRR
                     PRSQKIAEILTRMLSPLL"
     gene            6606..7550
                     /locus_tag="JYU28_RS05185"
                     /old_locus_tag="JYU28_05205"
     CDS             6606..7550
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280287.1"
                     /locus_tag="JYU28_RS05185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05205"
                     /product="YitT family protein"
                     /protein_id="WP_029516224.1"
                     /transl_table=11
                     /translation="MSVVSKEVQSLSEITDVTGELTKISKIPANPKNKVKRLFQRAAMI
                     VVGAALMAVGLEIFLVPNGVIDGGVTGISIMASKITGYPLGIFLTLLNLPFLLIGYKQI
                     GKTFALSTLFGIVVMSIGTALLHNVSALTPGEPLLGAIFGGVILGVGVGLVIRSGGSLD
                     GTEIVAILVSEKTPFSVGEIVLFVNIFILGSAGFVFGWPNALYSMIAYYIAMKMIDITI
                     EGLDQSKSVWIISDKYRDIGDALTDRLGRGVTYLEGEGGFTGESKKVIFVVITRLEEAK
                     LKSIVEDWDPHAFVAIGNIHDVKGGRFKKKGIH"
     gene            complement(7620..8522)
                     /gene="ligD"
                     /locus_tag="JYU28_RS05190"
                     /old_locus_tag="JYU28_05210"
     CDS             complement(7620..8522)
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369853.1"
                     /locus_tag="JYU28_RS05190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05210"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_029516225.1"
                     /transl_table=11
                     /translation="MGQAVKGTITIEGQEIPITNPDKPLWPEAGVTKALYLRKLAVLAP
                     FLLKYCHHRLLTVIRWPHGIHGDFFYQKNAPRPRPDYIETALHDGIEYIVLGKLPQLLW
                     LGNQAALEFHPSLHEAGNKLPCEWMIDLDPSREVEPRIMEAASIVGEVLASLGLDSVPK
                     TSGATGVQIIVPIRTGITFDELRSIGLLVGQFVTEKHPHLFTLERLKKDRGTAIYFDYL
                     QHYQGKTLAAPYTPRARPGATVSTPLTWEEVRQDVSPLDYHLLNIEERLNQVGDLIDKV
                     PPQPVEDVLKHMRTKAHRT"
     misc_feature    8669..8682
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.44"
                     /tool="antismash"
     misc_feature    8670..8683
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     misc_feature    complement(8672..8685)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.22"
                     /tool="antismash"
     misc_feature    complement(8672..8688)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.89"
                     /tool="antismash"
     gene            8736..10004
                     /locus_tag="JYU28_RS05195"
                     /old_locus_tag="JYU28_05215"
     CDS             8736..10004
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309190.1"
                     /locus_tag="JYU28_RS05195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05215"
                     /product="sulfotransferase"
                     /protein_id="WP_029516226.1"
                     /transl_table=11
                     /translation="MIEKQGGGLVFLLSVPRSGSSLLTAILQNHSRLFATQEMWFLLSL
                     YDLPQSHTRPYGGTGILRQFFKGMVPSDVLEQASRSYALEIYNGLLQGTTADMLIDKSP
                     RYYTVLEFIDRLFPAARRLWLIRNPLAIVASFKKVNQLRNGRFQLLEELGSPHFNMKMT
                     DITVGLFRYTHYFATPHPLAYPLRYEQLVSNPTMEIEKLCSFLGIHYEAGMEKYGDFAD
                     TPKSSLFYSMGAGDPFVGEHEQAHQDSVHSWQHVLSKREIELYCRSIGSRMFKQLGYAE
                     ALEQAEQMTGVRFEDEPDMELLSRRTQQFLQQSGFEWKAAYRMLEEQDTDNRELMTNAI
                     HHTPPQDPTWMHVDQSVNDRRIQSLENRLAHSYEERNRLIAQLQSYQRPHQGLRSRSLL
                     ARKLRYLASVALSSIGKEKGGRT"
     gene            10001..11926
                     /locus_tag="JYU28_RS05200"
                     /old_locus_tag="JYU28_05220"
     CDS             10001..11926
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369855.1"
                     /locus_tag="JYU28_RS05200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05220"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_029516227.1"
                     /sec_met_domain="GATase_7 (E-value: 3.8e-21, bitscore:
                     71.7, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1e-24, bitscore:
                     84.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYSFGHESVCTEEGGKMMQALRKYPADRVCAWCEGSIFL
                     GCHAQYVTPESVHERLPFYDELRDLAITADAIIDNRSELFERLGVEQERRQDITDSELI
                     LLAYDKWGVEAASYLIGDFAFVIWDAKEYRLYGARDMTGHRTLYIYQHDRGFAFSTVVA
                     PLLALSSLRKELHEPWLAEFLSIRTMQESVDIGTTAYKHINQLPPAHWFTMEEGKRTLH
                     KYACLDEVEPLRLKTGGEYIEAFHEVFTQAVTARLRTHRAVGAALSGGLDSGAVASFAA
                     PALHLQQKPLHAYSYVPVQDFTDWTPPTLLANERSYIHSTARYVGNIHENYMDFEGKSP
                     FSEIDIWLDLMEAPYKYFENSFWIRGFYEKAQEHNVGVLLTGARGNFSVSWGPALDYYA
                     RQFRHLHWLQSFQGLRRYSKLTGRRMSHLLPVMLKKATSLEPRLWLRRGHRSPVPSLIH
                     PEFAQRMNVEDIPVLSGTGWMKNADQTRKEKFSNLAIANKNGVVATKLSLRYGLWERDP
                     TGDSRVIRFCLSVPFEQYVQNGRDRALIRTAMRDHLPDDVRLNQRVRGVQPADWLHRML
                     PCWDTFMGELQLMCHDLRAAEYLNIEFIKTAMAKLHHPGPEQASDPNIRLLMHSLIVYR
                     FLCRFN"
     gene            11979..12107
                     /locus_tag="JYU28_RS05205"
                     /old_locus_tag="JYU28_05225"
     CDS             11979..12107
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369856.1"
                     /locus_tag="JYU28_RS05205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05225"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_134902123.1"
                     /transl_table=11
                     /translation="MSKKEWQEPTIEVLDISQTMAGKGWRQIDWVSDHDADIYNPS"
     gene            12307..13350
                     /locus_tag="JYU28_RS05210"
                     /old_locus_tag="JYU28_05230"
     CDS             12307..13350
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349787.1"
                     /locus_tag="JYU28_RS05210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05230"
                     /product="serine kinase"
                     /protein_id="WP_029516228.1"
                     /transl_table=11
                     /translation="MHDRSANVSWTKYTAFGLRIASELNLPELMLAAPGVVEDVVIRQA
                     DLTAWSGQLEQANFVMLDERFMFRIPGTAIYAVREGKEIEVSIFSGADPDTVRLFVLGT
                     CMGVLLMQRRILPIHGSAVVIGGRAYAFVGESGTGKSTLAAVFRQAGYQMVSDDVIAVK
                     ATGSSAIVYPAYPQQKLGLESLLQLEALRENKHVRKRKHIQSLTDDNSVMPQYTDLRTL
                     AGELNKYAVPAVDDFYNDPLPLGGVFELVADSPTRALMREGELVAVTEQPLNVLECLHT
                     LLQHTYRRVIIPRMGLSEWSFDTAARMARKVEGWRLLRDSSVFTASEVVQRVLELIRKE
                     EKSYGSH"
     gene            13337..13639
                     /locus_tag="JYU28_RS05215"
                     /old_locus_tag="JYU28_05235"
     CDS             13337..13639
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309193.1"
                     /locus_tag="JYU28_RS05215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05235"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_029516229.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.8e-26,
                     bitscore: 86.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2e-17, bitscore: 59.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATNPAKDHYRVIYNEEVYVSDMDGEKVMMSINTGKYYNLGYTG
                     GRIWELAESGPSLGDIVTVLTNEYEVDEEQCRQQVHTFVAELEREGLLKLLREPV"
     aSDomain        13382..13618
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JYU28_RS05215_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.30E-27"
                     /identifier="RREFam002.1"
                     /label="JYU28_RS05215"
                     /locus_tag="JYU28_RS05215"
                     /protein_end="94"
                     /protein_start="15"
                     /score="86.6"
                     /tool="antismash"
                     /translation="NEEVYVSDMDGEKVMMSINTGKYYNLGYTGGRIWELAESGPSLGD
                     IVTVLTNEYEVDEEQCRQQVHTFVAELEREGLLK"
     gene            13641..14126
                     /locus_tag="JYU28_RS05220"
                     /old_locus_tag="JYU28_05240"
     CDS             13641..14126
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821220.1"
                     /locus_tag="JYU28_RS05220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05240"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_029516230.1"
                     /sec_met_domain="PF13471 (E-value: 9.5e-25, bitscore: 83.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQRLLLLSPEVRRLLPEAWLELGWARLRQRRSFWDYSRAWGIR
                     MEETPWQCDVGQEKSIQQISHAVELASSYTPWRSSCLVQAAAAMTLLGRRKLDCTLYLG
                     TAKNAAGRLAAHAWVRSGPIYVTGKREMEAFTVVGIFGRRAVMDTNKNMEDKSSSLL"
     gene            14155..15648
                     /locus_tag="JYU28_RS05225"
                     /old_locus_tag="JYU28_05245"
     CDS             14155..15648
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426482.1"
                     /locus_tag="JYU28_RS05225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05245"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_208332459.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.7e-81, bitscore:
                     269.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTKSVLELANWNEDQELTLLLSLLGKDVIHWQDTTAATQLREMD
                     WVRFLRLTEHHRVVPTVYLQLKTLNHPFIPAELLRNLQAQYHRNTLRMLHLQAEAERLT
                     RLLIAHGIRVLMLKGPALAQQLYGDVSLRTSKDIDLLIAPDDMDEAEHWMQEAGYSSKS
                     GEVRVLGSWKWKDHHASYLHPQKRVEIELHWRLHPDGGGEPSFNELWNCRKKGKAAGAI
                     RQVPLGSADNRTVMTSCMYTLGSEHQFLYLSAHGARHGWFRLRWLVDIDRLAICAVDWE
                     ALLPMMRRYGGLPAGGQAWALAAALLGTPIPEPMRPVSATRQAHRLALSALAFMQASVP
                     ALYPITHGSGTGRLAPSELLHSRALAEQAEAAPPGGGPSVCSTSGEAAMLATRGVTSIT
                     EDASNDNHNPMSTAASCAPMTPAAASSQVMTKNRAVYQPVSRTYLLSLKEPRHRLWYLI
                     SRLFPSTGDSSVFPLPRQLHFLYIPLRPFLWLKRRFSKH"
     misc_feature    15754..15766
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            15791..17650
                     /locus_tag="JYU28_RS05230"
                     /old_locus_tag="JYU28_05250"
     CDS             15791..17650
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821218.1"
                     /locus_tag="JYU28_RS05230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05250"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_029516232.1"
                     /transl_table=11
                     /translation="MVHLRLYMTKLYSVNGGALFLNIGCMIIVSLLEGFGIYMLVPMLA
                     AIGVFVGHSGMPFLSDGLDHFLPFVPKSWLLPGMLMVFVVLLTGQALLQRYQSILNSRI
                     QQRFMRSLRIDVYTSFMKAQWAFYLRQRKSDFSHVMTTELARVSQGTNLLLQLTTAVMF
                     TLIQIALAFWLSPSLTGLVFLSGLGLFVVFRRSIRNAKQLGDRTTELSQVYFAGITDHM
                     NGMKDIKSNLLEAANIHWFRSLTQRMEDNTTQFVRQNATTQFFHRAVAAVFVACVIFIS
                     LQWLHVTPEKLIVLILIFSRLWPRFALIQASLEYIMSMISAFESVTKVQQECEAFTDPS
                     LIALASSETRVPSDPSVVNLSSASERQPLSLRQGIECSHLDYRYEGAAEPALRHINLFI
                     PAREMTAIVGKSGAGKSTMVDVLMGFLRPTGGQITIDGLVLGDELLPQWRQSFGYVSQD
                     PFLFHATVRENLMLADKDASEQQLWEALHFAAADNFVSRLPEGLDTIIGDRGIRLSGGE
                     RQRLVLARAILHHPPILILDEATSALDGEHEAAIQAALERMKGQMTLIVIAHRLSTIRH
                     ADQIVVLDQGEVIQQGNYRQLEQEERGAFSQLLSYQSSVTATP"
     gene            complement(17673..18587)
                     /locus_tag="JYU28_RS05235"
                     /old_locus_tag="JYU28_05255"
     CDS             complement(17673..18587)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309197.1"
                     /locus_tag="JYU28_RS05235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05255"
                     /product="Ku protein"
                     /protein_id="WP_029516233.1"
                     /transl_table=11
                     /translation="MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYV
                     RKCPVCDKEVEWEEIGKGYEYEKGKFVMFDKEELEQVSGQADKNIVILDFVDLQEIDPI
                     YFQKTYYLSPDQAGSNAYKLLMNAMKDTGKIGIAQISIRSKSSLAAIRVLDECLAVETM
                     FYPDEIRPIAQVPNLPGQEEVKEKELTMAKMLIEQLSTPFDAAKYTDQYRERLLDLIQH
                     KVAGEEVRIAPTQPQTNVVDLMAALQASIEAVQPVVTDPGPAAKKRPARKPAAPTAQQA
                     VAGDNLSPTPVKKKRSTAKRKET"
     gene            18798..19037
                     /locus_tag="JYU28_RS05240"
                     /old_locus_tag="JYU28_05260"
     CDS             18798..19037
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369863.1"
                     /locus_tag="JYU28_RS05240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05260"
                     /product="hypothetical protein"
                     /protein_id="WP_029516234.1"
                     /transl_table=11
                     /translation="MSGKSYPRQISHRVGQSHIAFRGPAAGEQDALPPEFALSHGTQPP
                     FPVAVAHVDLEAVVSTSPSHSFPSLDVERLIDED"
     gene            19090..19269
                     /locus_tag="JYU28_RS05245"
                     /old_locus_tag="JYU28_05265"
     CDS             19090..19269
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309199.1"
                     /locus_tag="JYU28_RS05245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05265"
                     /product="H-type small acid-soluble spore protein"
                     /protein_id="WP_069011105.1"
                     /transl_table=11
                     /translation="MNVERAKAIYDSSENIAVQLDGKPIWIEHVDEANGMATVQVGSNP
                     GNTQTVRVDRLEEQ"
     gene            complement(19743..20399)
                     /locus_tag="JYU28_RS05250"
                     /old_locus_tag="JYU28_05270"
     CDS             complement(19743..20399)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369865.1"
                     /locus_tag="JYU28_RS05250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05270"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_029516236.1"
                     /transl_table=11
                     /translation="MNNREFIARRIAQEFKSGEVVNLGVGLPTMVVDYIPEDIHIMLQA
                     ENGILGVGPKAAQGKERLDCIDSGGNYVTTMEGACFFDSALSFSIIRGGHVDITVLGAL
                     EVDEKGNLASWMIPGKKVPGMGGAMDLVVGAKRVIVAMEHVNKNGAPKILEQCKLPLTA
                     VNVVKTIVTEKAVIDVIPGKGLMLKEIAPGLTVEDVQLATEAKLIVSPHLRAIAV"
     gene            complement(20396..21061)
                     /locus_tag="JYU28_RS05255"
                     /old_locus_tag="JYU28_05275"
     CDS             complement(20396..21061)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429861.1"
                     /locus_tag="JYU28_RS05255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05275"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_029516237.1"
                     /transl_table=11
                     /translation="MNNKVISAEEAVKKVKDGDTVMVGGFLAGGFPEELVRALVDTNPA
                     SNLAIVSNDTGTPELSIYKLVKSGRVKRIFASYIGSNPETGRLLMTKEAEVQLFPQGTL
                     AEKIRAGGAGLGGVLTPVGVGTVVEEGKKKIKIDEREYLLELPLKADVALIRAHKADEA
                     GNLVINGSSRNFNMVMATAAEYVVAQVDEYVKTGEIDPNHVNVPGIFVDAIVKVGENA"
     gene            complement(21103..21843)
                     /locus_tag="JYU28_RS05260"
                     /old_locus_tag="JYU28_05280"
     CDS             complement(21103..21843)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686439.1"
                     /locus_tag="JYU28_RS05260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05280"
                     /product="acetoacetate decarboxylase"
                     /protein_id="WP_039269579.1"
                     /transl_table=11
                     /translation="MNQKDVLSLQSMPAASGSYGRPPYRFINREFFIITYETDPAAIRQ
                     AVPEPLQPDGSNTVSYEWIKMPDSSGLGSYEESGIVIPCTFQGEPCNFVAQMYLDNAPA
                     ILGGREVWGFPKKWAKPRLIVEETETLTGTLHYNNVLVATGTMPFKYNILDEKETAKAI
                     AKTQVNLKLIPDVDGTPKIAQLVAYNLENITVKGAWSGPARLSLIPHVNAPVADLPVKS
                     YIGGKHFIADLTLPYGRVLYDYLQ"
     misc_feature    complement(21892..21908)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            complement(21898..23082)
                     /locus_tag="JYU28_RS05265"
                     /old_locus_tag="JYU28_05285"
     CDS             complement(21898..23082)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429859.1"
                     /locus_tag="JYU28_RS05265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_05285"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_029516239.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.6e-06, bitscore:
                     22.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVALVSPLRTAVGSFNKTLAPLSASELGATVMTACLQQSKLEP
                     SLIDQIYLGNVLQAGNGQNPARQAALKAGIPIDVPETTINTVCGSGLHAVALAYNSILA
                     EQGNIVLAGGMESMSNAPYLLRNARNGYKLGNGELVDSLVADGLTCPINHYHMGITAEN
                     VADKYGISRMEQDEFAYQSQIKAVEAKNKKLFEEQIVPVMIKNKKETISFTEDEHIRGN
                     TTKEKLSQLKPAFKENGTVTAGNASGINDGAAAVLVVSEDKCKEHALKPLAYIKGYSLV
                     GVDPAYMGMGPVKAISTLLKQQGVSIDAIDLFEINEAFASQALAVVKELGVSLDKVNVN
                     GGAIAIGHPVGASGARILATLVHEMVRRSSRYGIASLCIGTGMGIAMLVENALI"
     misc_feature    23074..23087
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.09"
                     /tool="antismash"
     misc_feature    complement(23400..23413)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.78"
                     /tool="antismash"
     misc_feature    23400..23414
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.78"
                     /tool="antismash"
     misc_feature    23407..23421
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     misc_feature    23430..23443
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    complement(23431..23444)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.79"
                     /tool="antismash"
     misc_feature    complement(23432..23445)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.29"
                     /tool="antismash"
     misc_feature    24103..24119
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
ORIGIN
        1 gtttaccgta ttacggtcac tcagcattac aagacccgat tcggtaattt tgatatcgta
       61 cagccttgtt atgtgacgca ggaagatgag aaatggcggg tgctttggat atacaaggac
      121 aaggaataga ggttgcgagg tgtttctaaa aggttaaata tggtacaata cttccaaaac
      181 cggaaatgta cagtaaatgg ataacagctt cactccggat ggaaggagtt tcatagcatg
      241 cagcaagcga caggacaggt tcccgtcata cgtatggagg gtgtgagtaa aatcatttcc
      301 tccaaagcga tcgtggatga tctgacgctg gaggttccgg cggggcaggt atttggtttc
      361 cttggaccca atggtgcggg aaaaacgaca accatccgta tgatggttgg cctgatttcg
      421 atcagcaagg gcgatattca tatttgtgga gacagcatta atactgattt tgaaaaggcc
      481 gtttcccatg tcggagcgat tgttgagaac ccggagatgt acaagttttt gacaggctat
      541 caaaatttgc agcattttgc gcgaatgtct cctggggtga cccaagaacg cgtggatgaa
      601 gcgattcgtt tggtgggact cggaaaccgg attcacgata aagtaaaaac ctattcgctc
      661 gggatgcgac agcgacttgg agtagctcag gcgattttgc atcgaccgaa gctgcttgtg
      721 ctggacgagc cgaccaatgg tttggacccg cagggtattc gtgaactgcg ggattatttg
      781 cgtcaattga cccgtacgga gggaattacc gtattcgtat caagtcattt gttgtccgag
      841 atggagctga tgtgcgaccg tgtagccatt attcagagcg gacggctggt tgatatcaag
      901 caactgaaga acacagggga ggaagtgcag acggcggaaa ttgcttttga ggtaaatgat
      961 gccgaacaag cctatgcgct tgctggagca ggacgcgttg aaggtaatca actgctgctt
     1021 cacctggagc gggaacagat tgcagagatg aacagcctgc tggctgcaaa cggaattaaa
     1081 gtatatgcga ttcgcccggt tgcccgtacg ctggaagatc aatttttgga agtgacggga
     1141 ggcgggttta ttgggtgatt tcttcaaact ggtacataac gaaaatctga aaatttacct
     1201 gcgtgtgcgc acatggatta tgctgggatt gctggcggtc atcactgctg cgattccgat
     1261 gctgatctcc ctggtttccg atcaggtcag tgtgtgggat gggattgcgt tgacgacgtt
     1321 gtttacgttt ttcctcaata cgacgtttac ggtcattgta gctgctgatt cggtggctgg
     1381 tgaatttact tggggaacga ttaagctgct gctcatccga ccttggactc gcagcaaaat
     1441 attgttgtcc aagtatatat ccgtgatttt gttcagtttg ctcggaacga tcattttgat
     1501 cttgatggtt acgctgtcct catggctgat gttatccaag gatgcaccag cgggttctgt
     1561 tccgctgttc agtgatccga tatcttacgt aacgttgaac ttcttgtata gctatattgc
     1621 cttgttcgtg acgatggcct ttgcttttat gctgtccgct gttttccgtt ccagtgcctt
     1681 ggcgattggg ctgtcgctgt tcatgatgtt caccaaaaca atctataact ctattggctt
     1741 gttcagcaca gatcgttttg aatggaccaa atatgtacta tttacgcata tggatctgaa
     1801 aaaatatcta gatatgccgc cgggtacggt aagttccagt ctaacctttt cgctcaccgt
     1861 gctggccgct tattatgtaa tttttatcgc cattgcctgg gtggttttcg taaaacggga
     1921 tgtttcaacc taaatcgcag tgtcttagag ttacacaaag gacgttcaaa tgctcagcat
     1981 ttggacgtcc ttttgttatt tcaggatttt tcaaaattct ctttaacact gtttatccag
     2041 tatctatgtc atttttgtta catattctgc gtgcagaggt atattgtaat ctattttcag
     2101 caagaatcaa tcaatagggc cattttgcgt ttaaagaggt agagagaaac agaacagagg
     2161 gggccgcatg gtatgctgca aaataatcgt ttttttcgtg taactacagg tatcgtcatg
     2221 ctattactca tcatttactt gggcaccaaa gtaagcttta tatttagtcc tctcgtatct
     2281 ttggtcagct tgctggtggt accgttaatg ctatcttttt tcctctatta tttattgagg
     2341 ccgattgtag atgtaatgga acggagaaaa atcaaacgat cgatctccat cttgctgatt
     2401 tatttggtca ttggagtgtt attgtttgtt ttctcatggg gtgtgtggcc tacactgcgt
     2461 gatcaagtaa ccaatttatt tgaaaatgcg ccgaagctca ttaaaagtct ggttgatcaa
     2521 ttgagccaat ggcggcataa tcaatccttg agacaagtgc tgcctccggg tgaagacccg
     2581 ctgtcacaac tgtcagatac gttgaacgaa gctttttcga cgctatctga ttattcggta
     2641 aagctggtat cgttcgtgtc ctactttttt atcgtattgg ctacctttcc catattgctc
     2701 tattacatgc tgaaggaagg gagcaagttt ggccctaaaa tgctaaactt ctttcctaaa
     2761 aaatatcaca aggacgcatt ggaggttatg gaagatatcg atagtgcact cagcagcttt
     2821 atcgtaagtc gggtgctgat caatgtcgcg ttgggtgtga tgatgttcct tggattttta
     2881 attattggtt tgccttatgc cttgctgctc gccgttattt cgatttttct taattttatt
     2941 ccctatgtgg gggcagtggc tgcttctata cccgtggtta ttattggatt tctcgaatca
     3001 ccttcgatgg cgctctggtc gctggtcgtg gtgattgctg cacagcaaat tcaggataat
     3061 tggctgtcac ctatagtttt tggcaagcaa ctggatattc atccgttgac tgtcgttatt
     3121 ttactgttag ttggtggtga cctgctcggg attctgggca tcattttggt gattccattg
     3181 tatatgtgcg gaaaaatcgt catacgcaag gtataccaat tatttttgga acgcagagtg
     3241 gaggatatta tggaatgaat ggagaatgca ctggatttaa aggagtatat cctgatttta
     3301 ccctgcttcg gattgcagag tggcttggct gtcctccctg tctttgctga aactagattg
     3361 ggtttcgtcg tttggctcat ccgtagaagc tgacaactct acatcctttg ttcggttcat
     3421 ttgacttgtg ccgtccagta caccgccttc agagatgacc aatgcagcgg tcgcggtatt
     3481 tccgtacagc tcacctgtcg gcgtaatggt tagtcgtcct tctgtagtaa tgctgccgaa
     3541 caccttaccg gcaaggatga cgtcttgtgc gaagatgtcc gaacgtacaa cagcagattc
     3601 tccaatgacg acagtacgag tgctacggat atcgccctga aaatgaccgt caatccgaat
     3661 attggcctct gcttcaactg taccttcaaa gctggtgcca ttagcgagca gtgtatccat
     3721 agctggggtg gagagctttt ttttggattc cttaaacatg atggttttcc cccaatcttt
     3781 tattgtgaaa attttgcaaa atcctcattg tacatacagt aatggatcga caggttggtt
     3841 atgcttgacg atctgaaaat gaagatgagg tcctgtgctt ctcccggtac ttcccagcag
     3901 accgatggtc tgtcctttgt ggacacgatc tcctggagcc acctgcatgc cgctcaggtg
     3961 catataccag ctctggagtc cgtcaggatg ctggatgatg atgcacttgc cgcgggctcc
     4021 actagaagca gcctccaaga cggtgcctgc tcctgctgca tagacaggat caccggtttg
     4081 tccggcaatg tccacgcctg aatgaaaggc agatctaccc gtaaaagggt cgctgcgata
     4141 gccgaagctg gaggtcattc gccgtgaacc tacaggccaa acggagggtt tcccttgcac
     4201 ggcaagagcc agcctacgag tctggagtaa ctgtgcggct tgtttgcgct ccagattttg
     4261 ctggacggca tttgcttgct gaatagagcg gggaaccgta cgctccaccg tgtccaacag
     4321 agattcgatc tcctgaaaat catccattgc ctggcgagtt aggaaggcag tattttcatg
     4381 tactgcgatc agctcacccc caatatggcc ggaagcatcc caggagagcg gagtcatggt
     4441 ctttttatgg ttacttgtgg cagatgagtt tccgtgttta cgaatgaatt gttgcatttg
     4501 ctgttccagc tccgttacgc gctgaaggcg ttcacgaata tgggtggctt gatttgtcag
     4561 ctccatgact tcctgccgta gtcgcccaat ggctgcatcc ttgtccgcta ccgtgacctc
     4621 catctgcaaa ctctggacag caagattcgt ttccatttgg gaaataatat gggaagaacg
     4681 gatttgcagc ccgatcacga gcgtagagat agacgcgatc acaagagtcg ggacgagaat
     4741 gacagcggct gtagagcatt gtagctgctt gggcggttgc tgtgcatccc gaataacaag
     4801 cagggtcatc cggcgattta ggcttccttt tttcataatc gctcctttcc ggacatcgct
     4861 cctatagtgc ttggttacta tctattcagc ttaagaggca aacatgtcaa aaaaattgga
     4921 gcttagtata aaacgtagat gaggattttg caaaatcctg agatatataa ggaggcttag
     4981 acatgctgtg gttgctgttg gttttaattg tttttatttt tcagaccggg acgatcctgc
     5041 tctttgaatt tcgcaagccg tccaaagcgg tagcctggct ttttattttg ttttgcttcc
     5101 cgctcattgg ctttgtcgtg tactactttg ttgcacagga ttatcagaag cgtaaagtgg
     5161 ttcgaaaagg gggatcgcag ctgtttcgtg aattccgcga gcgtctatgg gcgcaatcca
     5221 aggtcattga acatgtggag caaatgcata atcctcattt caaacatcag gagcgcctgt
     5281 ttaaccagtt aattcgtatg tcggaaaacc cgttgactgg atgtaaccgc acacgtgtgc
     5341 tgacgaacgg tgaagaagcc ttcgaggcca tgctggcagc gatggaacat gcgcaacatc
     5401 atatccatgt ggagttttac atatttcggg ccgacgaaat cggaagaaag tttcaagagg
     5461 tcatgatccg caaggcacgt gagggagtaa aagtacgatt cgttgtagac ggtgtgggga
     5521 gctacaattt accctattcc tttattcgca cctgtagtga ggcgggagtg gaatttcatt
     5581 attttctacc tccgtttttc gccacactgg accgccggat taactatcgc aatcacagga
     5641 aaatcgtggt ggtagatggc atggttggat ttgtaggagg gattaatgta ggcgacgatt
     5701 atctcggaaa ataccccaaa gtaggatttt ggagggatac gcatttgcag attgaaggag
     5761 atagcgtcta ttttctacaa aatgcgtttc ttagtgactg gaagctggcc tcaggggaga
     5821 gactgatgga tgtgaattta tttcctccac atacctgtac cggggatgag gaagtacaga
     5881 ttttgagcag cggtcccgat caggtatggg atacgattca ggaaatgtgc tttggggcgc
     5941 tcacagttgc caaaaagcgg atttggatta cgacgccgta ttttattccc gatccgggca
     6001 tttatgaggc gctcaagctg gcggcagtca gtggcgtaga tgtgaaaatt attattccct
     6061 atcagtccga ttcgaagtta gttcatttgg cgtctctgtc ctatgtacaa gaactgctgg
     6121 aggcaggggt ggagttctac caatatcgaa aaggatttat tcatgccaaa gtggtgattg
     6181 tcgatgattt actcggctcg gtcgggaccg ccaatatgga catgcgcagc tttttctata
     6241 attttgagtt gaccgctgta gtttttgcta attcagcgct ggaacggctt tcggcagatt
     6301 ttgtagagga catttccaac tcctcacgca tagatttaaa cgtgttccgc agacggccta
     6361 gatctcagaa aatagctgaa attctaactc gcatgctctc tccactcctt taaaggcgat
     6421 tttcgtcgtt tttatcgcta taatcccgct ttattgtgat ttatgtgctc tttgctaact
     6481 tttttgcgcg aaatcacagt tttgtgatat actatttata taaatagcgc ggtaatgaat
     6541 aggggactgc ggatagcagc cccttttttg tccaatatat catactgtaa cggggggatt
     6601 tatatatgag tgtagtgagc aaggaagtcc aaagtttatc tgagattaca gatgtgaccg
     6661 gagagttgac caagatcagc aaaattccag ctaatccaaa gaacaaagta aaacgcctgt
     6721 ttcagcgtgc agccatgatt gtagttggtg cagctctgat ggcagtggga ttggaaatat
     6781 ttctagttcc taacggcgtt attgacggag gcgttacagg tatttccatc atggcctcca
     6841 agattactgg ctatccgctc ggtattttcc tgaccctgtt gaaccttcca tttttactta
     6901 tcggctacaa acaaattggt aaaaccttcg ctttatccac attattcggt atcgtcgtaa
     6961 tgtccattgg aaccgcgtta cttcacaatg taagtgcgtt gactcctggc gaaccgctgc
     7021 tcggcgctat ttttgggggc gtcattctcg gtgttggggt gggtcttgtg attcggtctg
     7081 gcggttcgct ggatggaaca gagatcgtag ctattctcgt cagtgaaaaa actccttttt
     7141 cggtcggtga gatcgtgctg ttcgttaaca tattcattct gggaagtgca ggttttgtgt
     7201 tcggttggcc aaatgccctg tattccatga ttgcttatta tatcgccatg aaaatgattg
     7261 atattacgat tgaaggtctg gatcagtcca aatcggtctg gattattagt gacaaatacc
     7321 gtgatatcgg ggatgccctg acggatcgtc ttggacgggg cgtaacttat ctggaaggtg
     7381 aaggtggctt tacaggcgaa agcaagaaag tgattttcgt cgtcatcacc cgactggagg
     7441 aagcgaagct gaagagcatc gttgaagatt gggacccgca cgctttcgtt gcgatcggta
     7501 acattcacga tgtgaagggc ggacgcttta agaaaaaagg aatacactag cgcaagggga
     7561 caattcctca gcctaatggc tgtggggttc gtcccctttt ttattcttcc aagcatggat
     7621 caggttcggt gtgccttggt gcgcatatgc ttgaggacat cttctacagg ttggggagga
     7681 accttgtcga tcaagtcgcc tacctgattt agtcgttcct caatattcag caaatggtag
     7741 tcaagtggtg atacatcttg ccgtacctct tcccatgtta gcggagtgga gaccgtagcg
     7801 ccggggcgtg cccgcggggt ataaggagcg gccagagttt tcccctgata atgctgcaaa
     7861 taatcaaaat agatggctgt tccacgatcc ttctttaacc tttcgagtgt gaacagatgc
     7921 gggtgctttt ctgtcacaaa ctgtccgact aatagcccga tgctgcgaag ttcgtcgaag
     7981 gttatgcctg tacggatcgg aacgataatt tgtacacctg tggccccgga tgttttgggg
     8041 acggagtcca aaccaagcga agccagtact tcaccgacaa tagaggctgc ctccataata
     8101 cgtggctcca cctctctgga tggatcaagg tcaatcatcc attcacaggg cagcttgttt
     8161 cccgcttcgt gcagagaggg gtggaattcc aacgcagctt gattaccaag ccagaggagt
     8221 tgtggcaatt tgccgagcac gatatattca atgccatcat gcagggcggt ttcaatatag
     8281 tccggccgag gacgtggggc atttttctga taaaaaaaat caccgtgaat cccatgtggc
     8341 cagcggatga cggtcagcag acgatgatga caatatttga gcaggaaggg agccagtacc
     8401 gcgagcttgc gaagatacag cgccttagtc acgcctgctt caggccacag cggtttatcc
     8461 gggttggtga taggaatttc ctgaccttca atggtaatag tacctttaac agcttgtccc
     8521 attgtgctat cctcctttgg ctaatatgca gcaaaatctt tatttacagg ctgattgtta
     8581 agcttttaga tctacatagg gtttaacatg aacgtgaagt gctgaattta tccatcaaaa
     8641 ggattgacaa gatacattat gtatcataaa tttataataa aaatacgata tgtatctatt
     8701 aaagtgtctt gagcagaggt agaggaggag tttgcttgat tgaaaagcaa ggcggagggc
     8761 tggtattcct gttaagtgtc cctcggagtg gaagctcgtt gcttaccgcc attttgcaaa
     8821 accattcccg cctgtttgcc acgcaggaaa tgtggtttct gctcagttta tatgatcttc
     8881 cgcagtcaca tacacgccca tatggaggaa cagggatact ccggcaattt tttaaaggta
     8941 tggtcccctc cgacgtattg gagcaggcct cccgttcgta tgcacttgaa atatataatg
     9001 gtttgcttca aggtacaaca gcagatatgc ttatcgacaa atccccgcgt tactatacgg
     9061 tgctggaatt tatagaccgt ttattccctg ctgcccgcag gttgtggctt atccgaaacc
     9121 ctttggccat tgtggcctca ttcaaaaagg tcaatcagct acggaacgga cgttttcaac
     9181 tactggagga actggggagt ccgcatttta atatgaaaat gacggatatt acggttggtt
     9241 tgttccgtta tactcattat tttgctacac ctcatccact tgcatacccg cttagatatg
     9301 aacagctcgt atccaatcca acgatggaga tcgagaaact gtgcagtttt ttgggaatcc
     9361 attatgaagc ggggatggaa aagtacggag atttcgcgga tacgcccaaa tccagtcttt
     9421 tttatagtat gggagcgggc gatccattcg taggagagca tgaacaggcg catcaggatt
     9481 cggtacatag ctggcaacat gtgttgagta aaagggaaat tgagctgtat tgcagaagca
     9541 ttgggtcccg catgtttaag caacttggtt acgcggaagc gctggagcag gctgaacaga
     9601 tgactggagt tcgctttgaa gatgagccag atatggagct gctgagtcga cgtacacaac
     9661 aattcctcca gcaaagcggc tttgaatgga aggcagctta tcggatgctg gaagaacagg
     9721 atacagataa cagagaactc atgacaaatg caatccatca tactccaccc caagatccga
     9781 catggatgca tgtggaccag agcgtgaacg atcgacggat ccaatcactg gaaaacaggt
     9841 tggcacatag ctatgaggag cggaaccgtc ttatcgctca gcttcaaagc tatcaacgcc
     9901 cacatcaagg tctccgatct cgcagcctct tggcccgtaa actcaggtac ttggcgtctg
     9961 tagcattatc aagtatagga aaagaaaaag ggggaagaac gtgagtgcga ttgccggaat
    10021 ctatagcttt gggcatgagt ctgtatgcac cgaagaaggc gggaaaatga tgcaggccct
    10081 gcggaaatat cccgctgacc gcgtatgcgc ttggtgtgaa ggctctattt ttttgggttg
    10141 tcatgcccag tatgtgaccc cggaatctgt tcatgagcgt cttccctttt atgatgagct
    10201 aagagatttg gcaatcacgg cggatgcgat tattgacaat cgttccgagc tgtttgaacg
    10261 gctgggagtt gagcaggaac ggcggcaaga tatcacggac agcgagctga ttttgctggc
    10321 atatgacaaa tggggagtgg aggcagccag ttatctgata ggtgattttg cctttgtcat
    10381 ttgggatgcc aaggaatatc gattatatgg tgctcgagat atgacaggcc atcgtacgct
    10441 gtacatctac caacatgacc gaggattcgc gtttagcacg gtagtcgctc cgcttttggc
    10501 cctgtcctct ctgcgaaaag aactgcatga accgtggctg gccgaatttt tgtccatccg
    10561 caccatgcag gaatccgtcg atatcgggac gaccgcctac aagcatatca accagcttcc
    10621 tcctgcacat tggttcacta tggaggaggg gaagcgaacc cttcataaat atgcatgcct
    10681 ggatgaggta gagccactgc ggctcaaaac aggaggtgag tacatagaag ctttccacga
    10741 ggtgttcaca caggcggtca ctgcccgatt acggacgcat cgcgctgtag gggctgcctt
    10801 gagcggaggg ctggattccg gagcggttgc cagctttgcc gcgccagcgc tgcacttgca
    10861 acaaaagccg ctacatgcct acagctatgt gcctgttcaa gattttacag actggacacc
    10921 gcctacattg ctggcgaacg aacgaagcta cattcattct acggctcgct atgtgggcaa
    10981 cattcacgag aactatatgg attttgaggg aaaaagtccg ttttcagaaa ttgatatttg
    11041 gctggatttg atggaggctc cctacaaata ttttgaaaac tccttctgga tcagaggttt
    11101 ttatgaaaaa gcgcaggaac acaatgtcgg tgtactgttg accggggcac gaggcaattt
    11161 ttccgtatcg tggggccctg cactggacta ttatgcccgt cagtttcgtc atttgcactg
    11221 gttgcaatcc tttcagggat tgaggcggta cagcaagctt acgggcaggc gtatgtctca
    11281 tctactcccc gtgatgttga agaaagcgac ttcacttgaa cctcgtttat ggctgcggcg
    11341 tggccatcgc agtcccgttc cttcactgat tcacccagag tttgcccaac ggatgaatgt
    11401 agaagatatt cctgtattga gcggaacagg ttggatgaaa aatgccgatc agacgagaaa
    11461 agagaagttc tcaaatttgg cgattgccaa caaaaatggt gtggtcgcga ccaaactttc
    11521 actacgttac ggcctatggg aacgtgatcc gaccggggac agccgggtaa ttcgcttttg
    11581 cttatcggtg ccttttgagc agtatgtaca aaacggtcgg gaccgtgccc tcattcgtac
    11641 ggccatgcgt gatcatctac ctgatgatgt tcggttgaac cagcgggtac gcggcgtgca
    11701 gcctgcagat tggctacatc gtatgcttcc ttgttgggat acgtttatgg gggagcttca
    11761 actgatgtgt catgatttac gagccgccga atatctcaat attgagttta ttaagacggc
    11821 tatggcaaaa cttcaccacc ccggccctga gcaggcgtct gatccgaata taagactact
    11881 catgcatagc ctgattgtgt accgttttct ctgtagattc aactgatcga atctgttcgg
    11941 tcagacagtt cgccattcgt tggaggggag gtgatgaaat gagtaaaaaa gaatggcagg
    12001 aaccgacgat agaggtgctg gatattagcc agaccatggc gggtaaaggc tggagacaga
    12061 ttgattgggt gtccgaccac gatgccgata tctataatcc aagctaatag atggttatac
    12121 atgttataca tgcagccaat gttggactgg aagccagaca actgggccga taacgattga
    12181 atgaacgaaa atagcatgat ccattggact cgtattcaat atacagccgt ctttatttct
    12241 ttcgggttag aggtgttgcc caagaaataa agacgggatt tttaaagaca gaggagtgag
    12301 tcctacgtgc atgacaggag tgcaaatgtc agttggacga aatatacggc ctttggactc
    12361 aggattgcga gtgagctgaa tctgcctgag ctgatgctgg cagcaccagg agtggtagag
    12421 gatgtagtca ttcgacaggc tgatttgact gcatggagtg gtcagctgga gcaggccaat
    12481 tttgtgatgc tggatgagcg atttatgttc cgaataccgg gcacggccat ttatgccgtc
    12541 agggaaggca aggagatcga ggtaagtata ttctctgggg ctgatcctga caccgtgcgg
    12601 ctgtttgtgc tgggtacatg catgggtgtt ctgctgatgc aaagacgaat attacctatt
    12661 cacggaagtg cggtcgtcat cggggggagg gcctacgcat ttgtgggtga atcgggtacg
    12721 gggaaatcga cattggctgc tgtttttagg caggcaggtt atcagatggt tagtgatgac
    12781 gtgattgctg taaaagctac gggttcctct gccattgtgt atccagctta tccgcagcaa
    12841 aagctggggc ttgaaagctt gctccaactg gaggctttac gggagaacaa gcatgtacgc
    12901 aaaagaaagc acatacagtc cctaactgac gacaattctg taatgccaca atacacagat
    12961 ctgcgtacgc ttgcaggtga gctgaataaa tatgccgtac ccgccgtaga tgatttttat
    13021 aacgatccgc tgcccttagg gggcgtattc gagctggtgg cagattctcc aacccgtgcg
    13081 ttgatgcgcg aaggggagct agtggcggtt acggaacagc ccttgaacgt tctggagtgc
    13141 ttgcatacat tactacaaca tacatatcgc agggtgatta ttccgcgaat gggtttgagt
    13201 gaatggtcgt ttgatacagc ggctaggatg gctcggaaag tggagggctg gcgcttgctg
    13261 agggatagtt ccgtctttac tgcgtccgag gttgtacaac gggtacttga actcattcgt
    13321 aaggaggaaa agagttatgg cagccactaa tccagctaag gatcattatc gcgtcattta
    13381 caatgaagag gtctacgtca gtgatatgga cggagaaaaa gtgatgatga gcattaacac
    13441 tggtaaatat tacaatttag gctacacagg aggacgaatc tgggaactgg cagaatccgg
    13501 tccttcactt ggcgatatcg taactgtcct gacgaacgaa tatgaggtgg acgaggaaca
    13561 gtgcagacag caggtacata cctttgtggc tgagttggag cgggaaggac tgttaaagct
    13621 tctacgggag ccggtataac atgcggatac aacggcttct tctcctgtct ccagaagtca
    13681 gaagattgtt gccggaagcc tggctggagc tgggatgggc gaggctgcgc cagcgtcgtt
    13741 ctttttggga ttactcaagg gcttggggca tacgtatgga agaaacccca tggcagtgtg
    13801 acgttgggca agagaagtcc attcagcaga tttcacacgc tgtagagctg gcaagcagtt
    13861 atactccttg gcgtagtagt tgtcttgtac aagccgctgc ggcgatgacg ttgctggggc
    13921 gcaggaaact ggactgcacg ctgtatctgg gtacagccaa aaatgccgct ggacgcttgg
    13981 ctgcacatgc atgggtacgt agcggaccga tttatgttac ggggaaacgg gagatggaag
    14041 catttacggt ggtggggata ttcggaagac gtgctgtgat ggatacaaat aagaatatgg
    14101 aagataaaag tagttcttta ctttaatgcg atgagacacg aaggagaaga atgcatgccc
    14161 accaagtctg ttttggaact tgcgaattgg aatgaggatc aagaattaac gttgttactc
    14221 tctctattgg ggaaggacgt tattcattgg caggatacga ctgctgctac ccagctgcgt
    14281 gagatggatt gggtccgctt tttacgtctg accgagcacc atcgagtggt acctacggtg
    14341 tatctccagc taaaaacatt gaatcatcca ttcattcccg cagaattgtt gcgaaacctt
    14401 caggcgcaat atcatcgaaa cacgcttcgc atgctccatc ttcaagcaga agccgagcgt
    14461 ctgaccaggc tgctcatagc tcatggaatt cgtgtgctta tgttgaaggg gcctgctctg
    14521 gcgcagcaat tatacgggga tgtttctctg cgtacttcca aggacataga cttactcatt
    14581 gcccctgacg atatggatga ggctgagcat tggatgcagg aagctggata ttcgtccaag
    14641 agcggagaag tgcgtgtcct tggcagttgg aaatggaagg accatcatgc atcctattta
    14701 catccgcaaa aacgggtaga gatagagttg cattggcggc ttcacccgga tgggggtggg
    14761 gaaccctctt ttaacgagct gtggaactgc cggaaaaagg gcaaagctgc aggagccatt
    14821 cggcaggtac cgttgggatc tgccgacaac aggactgtga tgacgtcctg tatgtatacg
    14881 cttggcagcg agcatcaatt tctgtacttg agtgcgcatg gtgcgcgtca cggttggttc
    14941 aggctgcgct ggctggttga catcgacagg cttgcgatat gtgctgtcga ttgggaggcg
    15001 ctactgccga tgatgcgccg ctacgggggc ctgcctgctg gcgggcaggc ttgggcactc
    15061 gccgctgcgc tgttgggtac gccgataccg gagccgatgc gtccggtatc ggctacccgg
    15121 caggcacata ggctcgcgct gagcgcgctg gccttcatgc aggccagcgt acccgcactg
    15181 tacccgatca cccacgggtc gggtacaggt aggcttgctc catcagagct gctgcacagc
    15241 agagccttgg cggagcaagc ggaggccgcc cctccaggtg gcggtccttc agtatgcagt
    15301 acctctggcg aagcagccat gcttgccacc cgtggcgtta ctagcatcac ggaagatgcc
    15361 agtaacgaca atcataatcc gatgagcacc gctgccagtt gtgccccgat gactccagct
    15421 gctgcctcca gccaagtcat gaccaaaaac agggctgtct atcagccggt cagccgcact
    15481 tacttgcttt ccttaaaaga gccaagacac agactatggt atctcatcag ccgtttgttt
    15541 ccttctacgg gcgattcgag cgtttttcca ttgcctcgcc agctgcattt tttgtatatc
    15601 cctttacgtc catttctctg gctgaagcgg cgattttcaa agcactgact cgatagagga
    15661 ttttgtgaaa atccaataag cggctttcaa tgaacaatat atagatcgaa atggtctagt
    15721 tcgtctatat aatgcacttt ggagcgattg ggatcgaatt ttgcaaagtc ctgaataagg
    15781 agtgtgcatt atggttcacc tgcgattata tatgacaaag ctgtatagcg tgaacggcgg
    15841 tgcgttattt ctcaatattg ggtgtatgat cattgtcagt ctactggagg gctttggcat
    15901 ttatatgctt gttcctatgc tggcggccat cggcgtattt gtcggtcatt cagggatgcc
    15961 atttctgtct gatggattgg atcatttttt gccgttcgtt cctaaaagct ggctattgcc
    16021 ggggatgttg atggtttttg tagtgctgct tacagggcag gctttgcttc agcgttacca
    16081 atccatcctg aattcgcgga ttcagcagcg ttttatgcgt tctcttcgaa tagacgtgta
    16141 cacttccttt atgaaggcgc agtgggcctt ttatttgcgt cagcgtaaat ctgattttag
    16201 ccatgtgatg acgaccgagc tggcgcgtgt cagtcagggg acgaatttgc ttcttcaact
    16261 gactacagcc gtcatgttta cgctgatcca gattgcgctg gctttttggt tatccccctc
    16321 tttaaccgga ctggtatttc tgagtggatt ggggctgttt gtcgtgttcc gccgctccat
    16381 tcgaaatgcc aaacaattag gtgatcgtac gactgaactg tcacaggttt attttgctgg
    16441 aattacggat cacatgaacg gtatgaaaga tataaaaagc aatctgttgg aagcggcgaa
    16501 tatccattgg tttcgctccc tgacgcaacg catggaggat aatacgactc aatttgtccg
    16561 gcaaaatgcg accacacagt tttttcatcg tgcagtggca gctgtttttg tcgcttgtgt
    16621 catatttata tcgctgcagt ggctgcatgt tacacctgaa aaactgattg tgctgattct
    16681 tatattttcc cgcttatggc ctcgatttgc tcttattcaa gcgagtctgg aatacatcat
    16741 gtctatgatc tccgcttttg aaagtgtcac caaggtgcaa caggagtgcg aagctttcac
    16801 agatccgtca ttgattgcac ttgcatcctc tgagactcgc gttccatccg atccatcggt
    16861 agttaatcta tcatctgcat ctgaacggca acccctgtcc cttcgtcagg ggattgaatg
    16921 cagccatctg gattatcgct acgagggtgc agcagagcct gcactgcgtc atattaattt
    16981 gttcataccc gcccgggaaa tgacagccat tgtagggaaa tcaggagcag gcaaaagtac
    17041 aatggtcgat gtcctgatgg gttttttacg tccaacaggg gggcagatta caatagacgg
    17101 gcttgttctg ggcgacgaat tattgcccca gtggcggcag tcgtttggct acgtgtcaca
    17161 agacccattt ttatttcatg cgactgtccg cgaaaatttg atgctggcgg ataaggatgc
    17221 tagtgagcag cagctatggg aggcgttaca ttttgcagca gcagacaact ttgtatccag
    17281 actgcccgaa gggctggaca cgatcattgg agatcgcggg attcgtctgt ctggaggaga
    17341 acgtcaacgg ctagtattag cacgggctat cttgcatcat cctccgatac ttatattaga
    17401 tgaagcgaca agtgcgctgg atggtgaaca tgaagccgca attcaggcag cactggaacg
    17461 gatgaaaggt caaatgacgc tgatcgtcat cgctcaccgc ctgtcaacca tcagacatgc
    17521 ggatcaaatt gtcgtactgg atcaaggcga ggtcatacag caggggaact accgccaact
    17581 ggaacaagag gagcgggggg cgtttagtca gctactatcg tatcaaagca gtgtcaccgc
    17641 caccccttaa ccagactttt ctgtaactca gcttaagttt ctttacgttt ggcagtgctt
    17701 cttttctttt tgactggagt cggagagagg ttgtcgcctg ccaccgcctg ctgtgctgtt
    17761 ggggctgctg gtttacgcgc agggcgtttt ttcgcagcag gaccgggatc ggtaacgaca
    17821 ggttgcactg cctcgatgct ggcctgaagg gcggccatta aatctactac attggtctga
    17881 ggctgggttg gggcgattcg cacctcttca ccagccactt tatgctgaat gaggtccagc
    17941 agacgctcgc ggtactgatc cgtatacttg gctgcatcaa aaggtgtaga tagctgctca
    18001 atcagcattt tggccatggt cagctccttc tctttaacct cttcctgccc cggtaagtta
    18061 ggaacttgag caatgggacg aatttcatcg gggtaaaaca tcgtctccac cgccaaacat
    18121 tcatccaaca cccgaatcgc cgccaagctg cttttagagc ggatggagat ttgggcaatc
    18181 ccgattttcc cggtatcctt cattgcattc atgagcagct tatacgcatt ggagccggcc
    18241 tgatccgggg ataaataata cgttttctga aagtaaatcg gatcaatttc ctgcaaatca
    18301 acaaaatcca aaatcacgat atttttatcc gcttgtccgc taacttgctc cagttcctcc
    18361 ttgtcgaaca tgacaaattt tcctttttca tattcgtagc cttttccaat ttcctcccat
    18421 tcgacctcct tgtcacaaac gggacacttt cgtacatagc taagtgggct tccacactcc
    18481 ttgtgaatgt aacgcatgga aatgtcctta tcctccgtag ctgaaaacat tttaacgggc
    18541 acatgaacca gcccgaagct gatcgcgcct ttccagaccg tatgcatacc gccagtcctc
    18601 cttctcttta atccgcattt tgcatccttc gattccgggc accccgggat atgagcatat
    18661 gattttcact tagtatgctt cgtataagtg attgtatgag atgtagatga agactgcgaa
    18721 ttgctgccgc ttgcgcatgg ttacagcaat tttggtacat agtaaggcat atccgattca
    18781 aagggggtac acaatttatg tccggaaaat cctatcctcg gcagatcagt catcgtgtgg
    18841 gtcaaagcca tatcgccttt cggggtcccg ccgcaggcga acaagatgca ttgccgcccg
    18901 agtttgccct ttcacatgga actcagccgc cttttcccgt tgctgtggct catgtggatt
    18961 tggaggctgt agtttcaacc tcgccttccc atagctttcc ttcattggac gttgaacgac
    19021 ttatagatga agactaggtg acctacattt gtaaattaat gcacaaacaa tcagcaggag
    19081 gagaacagca tgaacgtgga acgagcaaaa gccatttatg attcatccga aaatattgcc
    19141 gtacaattgg atggcaaacc gatttggatt gagcatgtag acgaagcaaa cggtatggct
    19201 accgtacagg tgggcagcaa ccccggcaat actcaaactg tccgtgtgga tcgtctggaa
    19261 gagcagtagg agatgggaac caaacatctg gtcattatcc atggccgtga caaaaagccc
    19321 agatgcgacg aaatgcttcg tcttattaaa aaagcactga tcgcaggatt gcgttgagtg
    19381 aacgaggaag cggcacaaaa actggagcaa gagcagattt tactgacatt taacggttga
    19441 aaatgatttc catctgatgc tgaatcgaaa tttaatagaa actattgatg atcagccgct
    19501 tattcagaca ttctggaaag atagtcacac tgggcgtgct aatccccaca acttctttgc
    19561 ttatcttaac catacgaagg tggctgagca tgtagcggat tggattttac gctcaaaaag
    19621 gctcgcaatt gctcgatgag caattagcga accttttttt gtaataacaa gtgcagtcgt
    19681 agggacgaat taaatgccag acaagttaat ttgaagatgc agctggttcc tttctatgac
    19741 cttcacactg caatggccct caaatgtggt gaaactatca gtttagcctc tgttgctaat
    19801 tgaacgtctt ccaccgtcaa acccggagca atttctttta gcatcagccc tttacccgga
    19861 ataacatcaa tgacagcctt ttcggttact atggtcttta caacatttac agcagtcaag
    19921 ggcagcttgc attgttccag tattttcggc gcgccatttt tgttcacatg ctccatggct
    19981 acaatcactc tcttggctcc aactaccaaa tccatggctc cccccatacc cggcaccttt
    20041 ttcccaggga tcatccagct tgcaaggttg cctttctcgt cgacctccag ggcgcccagc
    20101 acggtgatat ccacatgccc tccgcggatg atggaaaatg aaagtgcact gtcaaaaaag
    20161 catgctcctt ccatggttgt aacgtagttt ccgcctgaat cgatacaatc gagcctttct
    20221 tttccctgag ccgctttggg gcctacaccg aggattccgt tctcagcctg cagcataata
    20281 tgaatgtcct cggggatata gtccactacc attgtaggca atccgacacc aaggttgaca
    20341 acttcaccac ttttgaattc ctgggctatt cttcgagcaa tgaattctct gttattcatg
    20401 cgttttcacc cacctttaca attgcgtcga caaatattcc gggaacgttg acatgattgg
    20461 ggtcaatttc acccgtcttt acgtattcgt ctacctgagc aactacatac tctgccgctg
    20521 tagccataac catattgaag ttacgtgaag agccgttgat gacaagattc cccgcttcat
    20581 cagccttatg ggctctgatt aacgctacat ccgctttgag cgggagttcg agcaaatatt
    20641 ccctttcatc aattttgatt ttcttttttc cttcctctac aacggtgcct acacctacag
    20701 gtgttaaaac cccgcccaaa ccggctcctc ccgcgcgtat tttttcagcg agcgtgcctt
    20761 gcgggaagag ttggacctca gcttctttcg tcatcaggag ccttcccgtt tccggattgg
    20821 agccgatata ggatgcaaaa attcgcttta ctctgccgct ttttacaagc ttatagatag
    20881 ataattctgg tgtgcctgtg tcgttggaaa caatcgcaag attgctggcg ggattggtgt
    20941 cgacaagcgc acgaaccagc tcctccggaa agcctcctgc cagaaaacct ccgaccatca
    21001 ccgtgtctcc gtctttgacc ttcttaactg cttcttcagc ggagattact ttgttattca
    21061 tggttccttc tccttatata tatattttta ggaaagcaaa ctttattgaa gataatcgta
    21121 gaggactctt ccatatggaa gcgttaaatc agcaataaaa tgtttcccgc caatataaga
    21181 tttaaccggc aaatctgcca caggagcgtt gacatggggg atcaggctta atctggcagg
    21241 ccctgaccag gctcctttta cagtaatgtt ctcaagatta tacgctacta actgagcgat
    21301 tttgggggta ccgtcaacat caggaattaa ctttaaatta acttgtgttt ttgcgatggc
    21361 ttttgccgtt tccttttcat caagaatgtt atatttgaaa ggcatagttc ccgtggccac
    21421 caggacgttg ttataatgca atgtacccgt cagcgtctcc gtctcctcaa cgatcaagcg
    21481 aggctttgcc cattttttcg gaaatcccca gacttcgcgt ccccccagaa tagcaggtgc
    21541 gttatccaaa tacatttggg cgacaaaatt gcagggttct ccttgaaaag tacacggaat
    21601 gacaataccg ctttcctcat aacttcctaa cccggatgaa tcgggcatct tgatccattc
    21661 ataggaaacc gtattgcttc catccggctg aagaggttcc gggaccgcct gtctaatcgc
    21721 agcgggatcg gtctcatagg taatgataaa aaattcccgg ttgatgaatc ggtatggcgg
    21781 gcgcccgtag ctgccgctag ccgcaggcat ggattggagt gaaagtacat ctttttgatt
    21841 cataacggtc tcccttcctt ttaagagata ttctaaaatt catcttgaat acgcacttta
    21901 aatgagcgca ttttcaacca gcatcgctat gcccattcct gttccgatgc ataacgaggc
    21961 gatgccgtaa cgtgaagatc ttcgcaccat ttcatgaacc aacgtagcca atatcctagc
    22021 accgctggcc ccgacaggat gcccgatcgc gatcgcgccg ccattgacat tcactttgtc
    22081 cagactgacc cctagctctt tcactaccgc taatgcttgt gaggcaaacg cttcattaat
    22141 ttcaaaaaga tcaatggcat cgatggatac accttgctgc ttcagaagtg tcgaaatggc
    22201 tttcactggc cccattccca tatatgcagg gtcaacgcca acaagggaat aacccttgat
    22261 atatgccaat ggctttaatg catgttcttt gcatttgtct tccgacacca caagtacggc
    22321 cgccgcgcca tcattgattc ccgaagcatt cccggcggta accgttccgt tctccttaaa
    22381 cgcaggtttt aattgagaaa gtttttcttt cgttgtattt cctcttatgt gttcatcctc
    22441 tgtgaaagaa atagtttctt ttttgttttt gatcatgact ggaacaatct gctcttcaaa
    22501 aagcttcttg ttttttgctt ctacggcctt tatctggctt tgataggcaa attcgtcctg
    22561 ctccattctt gaaattccat atttatcggc aacattttct gcggtaattc ccatatggta
    22621 atggttgatc gggcatgtaa ggccgtcggc caccagggag tctaccaact caccgttacc
    22681 aagtttgtag ccgtttcttg catttcttag caggtaaggg gcattcgaca tgctctccat
    22741 gcctccggcc aagacgatgt tgccttgttc agccaatatt gaattgtaag ctaaagcaac
    22801 ggcatgaagt ccagaaccgc aaaccgtgtt tatcgttgtt tcgggtacat caatagggat
    22861 accggctttt aatgccgcct gtctggcagg attttgtcca ttgcccgcct gaagaacatt
    22921 tcccaaataa atctgatcaa tcaaagaagg ctctaattta ctttgctgaa ggcatgctgt
    22981 catcacggtt gctcccagtt cggaagcgct tagaggcgca agggttttgt taaaagagcc
    23041 gaccgctgtt cttaacgggc ttactaaagc tacttttttc attaaaaact cacattcctt
    23101 tcgctgtgtt aaaacacaat acatccatga ttgcacttca attggtaatt tccgctctta
    23161 acctacgaga cgcagcgatt gcaagatata tttgcatgcg ggcatatcat ggtgcctaag
    23221 acagtaaatg tgacggttcg atcgccttct cccattggaa attaaaacca gttttatcat
    23281 agttctaatg cagattttgc tcaatgtcca aatatttaca tatatctatg tacagatgtt
    23341 tatagggtca tataggccac aataattagg ccattctaac gttttctgtt attttcttgt
    23401 tttttctgaa aatcatgatc ataaattgaa ttttatgtta aaaatgaaag ttgcaatcca
    23461 tacgtaaaaa agttttcctc gcaaatatca tctaactcag ctggaaaata aaaaaagcct
    23521 ccagaatttt ctgaaggcgg ctttgtttct gaccaatctg gtcttgaaaa agctaggcag
    23581 gttgccaatc caattgaata catttggaat tccaataaaa atgatgacgt ctttgcgaga
    23641 tagtgaaaac ttgtgaattg gatcaatagc tcacgaaaaa tgtacatctg ctgtcgcgag
    23701 taaacgcaca aaacgattgc caagcagctc attatgatga gctacaattt gttcactgct
    23761 cagcaccttg ctatcaaatg tactatgcgc atccaatacg agcacgttgt tctggtatcc
    23821 cagactatag gcgcttcggc aagtcgtgtc gaggcaaaac tcggtctgca tccccgcgat
    23881 tacgagctga tcggccccca gttccttcag cacatggccc aattcggttt ggtagaagct
    23941 gtcccaggat gatttacgga caattcgttc atgaggaaga gggcgcacca catcggcgat
    24001 ggcccagcct acactgtttt cccggaaatc ctcatccgct tcatcggtat gctgtacaaa
    24061 aatcaccggt gtacctgtag ctctggcttt gtccaaaagc tgctgcaaat gcgatacaac
    24121 ttcctg
//
