LOCUS       NZ_JAFJXZ010000012     20237 bp    DNA     linear   CON 03-JUN-2024
DEFINITION  Paenibacillus polymyxa strain Hob6 Scaffold_12, whole genome shotgun
            sequence.
ACCESSION   NZ_JAFJXZ010000012
VERSION     NZ_JAFJXZ010000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 1543484)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Draft genome sequence of Paenibacillus polymyxa strain Hob6,
            isolated from hemp (Cannabis sative) seeds' oil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1543484)
  AUTHORS   Mahmoud,M. and Jabaji,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2021) Plant Science Departement, McGill
            University, 21111 Lakeshore, te-Anne-de-Bellevue, Quebec H9X 3V9,
            Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-JUL-2020
            Assembly Method                   :: SPAdes v. 3.12.0; Medusa v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly :: GCA_000507205.2; GCA_014706575.1;
            GCA_000164985.2; GCA_000597985.1; GCA_002893885.1
            Genome Coverage                   :: 266.29x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017589695.1-RS_2024_06_03
            Annotation Date                   :: 06/03/2024 02:57:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,275
            CDSs (total)                      :: 5,119
            Genes (coding)                    :: 5,024
            CDSs (with protein)               :: 5,024
            Genes (RNA)                       :: 156
            rRNAs                             :: 21, 9, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 19, 2 (5S, 16S)
            partial rRNAs                     :: 2, 7, 15 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 44 of 95
            Pseudo Genes (incomplete)         :: 63 of 95
            Pseudo Genes (internal stop)      :: 13 of 95
            Pseudo Genes (multiple problems)  :: 21 of 95
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:07:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 333574
            Orig. end                         :: 353811
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAFJXZ010000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20237
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proteusin"
                     /region_number="2"
                     /rules="(PoyD or TIGR03793)"
                     /tool="antismash"
     cand_cluster    1..20237
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20237
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10237](-)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10237)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     misc_feature    complement(31..45)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(856..1113)
                     /locus_tag="JYU28_RS04515"
                     /old_locus_tag="JYU28_04535"
     CDS             complement(856..1113)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821374.1"
                     /locus_tag="JYU28_RS04515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04535"
                     /product="YqkE family protein"
                     /protein_id="WP_029516109.1"
                     /transl_table=11
                     /translation="MAKKRNSSSPAPAPQDKPATLKDLLSQDVLNKLKAQANEAQAEQD
                     KRKEDERQRAVEAKKAEQKKLDNNFEHLLNNSNLDWHKYK"
     misc_feature    1150..1165
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.21"
                     /tool="antismash"
     gene            1245..2477
                     /locus_tag="JYU28_RS04520"
                     /old_locus_tag="JYU28_04540"
     CDS             1245..2477
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686325.1"
                     /locus_tag="JYU28_RS04520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04540"
                     /product="MFS transporter"
                     /protein_id="WP_069010364.1"
                     /transl_table=11
                     /translation="MHLYWKRNLVILWIGVLFCSMAYSVSIPFLPIFLNTEMGVNDHLE
                     LWSGTAFGVTFLASALIAPFWGSLADKYGRKPMLIRSGFSLAVLYLICAFVTDPYVFVG
                     VRLFQGLLSGFIPAAIALVGTGSPEEKTGYALGIMATAGATGSIIGPLIGGVVSHYYGN
                     RNAFFFSAALVLVSALIATFGAREDSFKGTRTRSHVRDDIKEAIANRPLYFLLILAGLS
                     TFSVMILEPLITVYVLEMGVDRSQASLSSGIVFSAVGIAAVLMAPRWGRIGGRTGFAHV
                     LLIGLIGSGIGNILQFYVTNFVGFGALRFGYGLFYASVMPAINAMTVEVTKPEFRGRAF
                     SLNQSATQLATMAGPLIGGMLGSWMPIRWIFVLNGGILLLAALLLWAKGKNVFPVSAKK
                     NVTDQDIHSAG"
     gene            2628..2807
                     /locus_tag="JYU28_RS04525"
                     /old_locus_tag="JYU28_04545"
     CDS             2628..2807
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369715.1"
                     /locus_tag="JYU28_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04545"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_023987319.1"
                     /transl_table=11
                     /translation="MIRDDILRQQLENARQKLYILQAKHGFNHASVLRQSVIMDNLINQ
                     YNHLFYIKEKKPTA"
     misc_feature    2658..2676
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.78"
                     /tool="antismash"
     gene            complement(2923..3825)
                     /locus_tag="JYU28_RS04530"
                     /old_locus_tag="JYU28_04550"
     CDS             complement(2923..3825)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686326.1"
                     /locus_tag="JYU28_RS04530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04550"
                     /product="EamA family transporter"
                     /protein_id="WP_039269437.1"
                     /transl_table=11
                     /translation="MNKVIAHHSESNRIYYGSTILALLIWSTSFIATKAAYTTFPPLTL
                     GLSRFIIASVVLGIVLLIKKEHVKVKPKDLATISFSGVLGITLYFSMENIGVSLTTASN
                     AALIVASYPAITSLLELILYKVKLSKYKICGIALAMIGVYFLTSVGESSDSKNQLIGNL
                     ILIGTGFAWAFYTFMTRKVVDKYPPVTLSFYQTVAGSIFFIPLALLEKDRWQVPTTGSF
                     MLLVYLGVFCSVIAFLLYNYGLIKLSPSSSVSLMNLVPIFGVLFSVLLLQETITWRQII
                     GGLVVIIGVLLSAHQTNRT"
     gene            3981..4841
                     /locus_tag="JYU28_RS04535"
                     /old_locus_tag="JYU28_04555"
     CDS             3981..4841
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369717.1"
                     /locus_tag="JYU28_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04555"
                     /product="TrmB family transcriptional regulator"
                     /protein_id="WP_069010365.1"
                     /transl_table=11
                     /translation="MKPKPNILEILRDLNFSEYEAKAYVTLLESSPLSGYAVSLNSGVP
                     RSKIYEVLSGMVNRGDIMISQENTPLYVPLPPHELIAQRKRKAEQIFNVAQESLEQYTA
                     SFQNRENIWNISGYEAIINRINEGVKGAKHRILLEIWKEDAEVFRDSLGQVAQQGIEVI
                     IVAYGELNFDFATVYRHDMSEEITSEIGGRWIVLSVDDREVVAGILSLGDDSRAAWTLH
                     PGLVMPITEVIIHDIYIMEILYEFREQLEEKFGPNLIHLRNKFAMGPNGKGYYIPLTEK
                     SMKRV"
     gene            complement(4928..>5095)
                     /locus_tag="JYU28_RS27095"
                     /pseudo=""
     CDS             complement(4928..>5095)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019910291.1"
                     /locus_tag="JYU28_RS27095"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="EKVNTIDLQGSDTNAVSFTVPADAKSGNTLHIIAEVQDNGKHPLK
                     HYQRVIVTVK"
     gene            complement(5335..6417)
                     /locus_tag="JYU28_RS04540"
                     /old_locus_tag="JYU28_04560"
     CDS             complement(5335..6417)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369718.1"
                     /locus_tag="JYU28_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04560"
                     /product="bifunctional 3-deoxy-7-phosphoheptulonate
                     synthase/chorismate mutase"
                     /protein_id="WP_029516113.1"
                     /transl_table=11
                     /translation="MSTNENSLELLREQLDATNLQLLELLSQRAELAGQLGKLKEAQGV
                     PDFDPVREQQMLDKLIAANRGPFDDATIRQLFKNIFKASLNYQKEEHKKHLIVSRKNQP
                     DSTIIKVKDTLVGGKASIMVAGPCSVESYQQTREVGAALKEAGVPILRGGAFKPRTSPY
                     DFQGLGVEGLQILKRVGDEFGLATISEIVDPRHLEEAIQYIDIIQIGARNMHNFELLKA
                     AGETRTPVLLKRGLAATMEEFLHAAEYIVSRGNTQVMLIERGIRTYEKWTRNTLDISAV
                     PILKKESHLPVLVDVTHSTGRKDILAPCAKAALAAGADGIMVEVHPNPAVALSDAQQQL
                     NIPEFHNFLSEVKESGLFKA"
     misc_feature    6400..6415
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.59"
                     /tool="antismash"
     misc_binding    complement(6506..6776)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            complement(6878..7057)
                     /locus_tag="JYU28_RS04545"
                     /old_locus_tag="JYU28_04565"
     CDS             complement(6878..7057)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821368.1"
                     /locus_tag="JYU28_RS04545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04565"
                     /product="hypothetical protein"
                     /protein_id="WP_029516114.1"
                     /transl_table=11
                     /translation="MYKDPMSQADMEYKRYKALNPVEADDRRTADKTNTDDTSTEDNPR
                     GVASANPEPRDQGK"
     misc_feature    complement(7114..7125)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.53"
                     /tool="antismash"
     gene            complement(7148..7408)
                     /locus_tag="JYU28_RS04550"
                     /old_locus_tag="JYU28_04570"
     CDS             complement(7148..7408)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369720.1"
                     /locus_tag="JYU28_RS04550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04570"
                     /product="hypothetical protein"
                     /protein_id="WP_029516115.1"
                     /transl_table=11
                     /translation="MANRDDRTTELHDNDFEPSLQNAETNWENLTEGPDTPLEDVPDAD
                     ELTPNSPVDPSAPAEFLHGTDLLNGTDGDEEDQLESDDMLD"
     misc_feature    7359..7373
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.27"
                     /tool="antismash"
     gene            7592..7879
                     /locus_tag="JYU28_RS04555"
                     /old_locus_tag="JYU28_04575"
     CDS             7592..7879
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369721.1"
                     /locus_tag="JYU28_RS04555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04575"
                     /product="hypothetical protein"
                     /protein_id="WP_023987328.1"
                     /transl_table=11
                     /translation="MEWYMFGPMISRIRVGQKASTPGFSRTLIRRPEGLYWTDGGQAGK
                     IVEIRDYLFSDIWTIYEDEDCEPWLGLREQKERREQEMIINQYEDFTKNE"
     gene            8012..9901
                     /locus_tag="JYU28_RS04560"
                     /old_locus_tag="JYU28_04580"
     CDS             8012..9901
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686330.1"
                     /locus_tag="JYU28_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04580"
                     /product="sensor histidine kinase"
                     /protein_id="WP_069010366.1"
                     /transl_table=11
                     /translation="MRHVPKAVAALLAVIVMLLSLGHSAYAAKMTPEGDYKIPSWDMRW
                     GEVDEDGSLDEVKNPSKIWMHIEDDTQLLRQPGNIGSAWIRIKLPSLSDETPAILFENI
                     YGRHITLYKDGTNFYESYRGYNYENNRILIPLKPEDSGKTLYIWTESSKKRLGIIGNVM
                     TGDYRDLLGTLVRMDVLDIVLGSTFIFIALVLLICSFFLFRPSMAMWLSLSAIVLSIGL
                     MIVTYSPFLYTFYRGYGKLYLQLFDVALFILLPSLAFFFEQNINSIILIRKFRKLLTAY
                     SLFCFTMMIVNLGAQERLNNIYYFFSVVILGILLVALMILLVFASVRMALKGDHEAIIL
                     STGFAFFAVISIGELSWFFILDGHYNMFLWKWGVFGFVLALIAILGRRLAEKHKQVVRY
                     SRELEMFNNELQRSEKMEIISDLAASVAHEVRNPLQVTRGFLQLMSKQEDGKNKDYLHI
                     ALEELDRASAIITDFLTFAKPEFDQTKTLTILDEFKHIEGIISPMANLQGGKISLDIPQ
                     EIKVRGNSSKFKQAFINIIKNSIEALRDQGLIHIWAYVDNGEAVIHIRDNGEGMDAQTL
                     SRLGEPYFSNKTKGTGLGMMVTFRIIETMNGKITFTSAKGVGTEATIRFPVAG"
     gene            complement(10001..10237)
                     /locus_tag="JYU28_RS04565"
                     /old_locus_tag="JYU28_04585"
     CDS             complement(10001..10237)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429107.1"
                     /locus_tag="JYU28_RS04565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04585"
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_013309068.1"
                     /sec_met_domain="TIGR03793 (E-value: 2.4e-19, bitscore:
                     65.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATEVLQTQVIQKAWEDASFREKLMTDPKSAIRDVLGVVIPDHIQ
                     IKTLEETPDQFFLVIPPDPSGVLAASQKPRSMW"
     gene            complement(10313..11248)
                     /locus_tag="JYU28_RS04570"
                     /old_locus_tag="JYU28_04590"
     CDS             complement(10313..11248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429108.1"
                     /locus_tag="JYU28_RS04570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04590"
                     /product="hypothetical protein"
                     /protein_id="WP_029516118.1"
                     /transl_table=11
                     /translation="MEWYFAYKDELEKVFRQAEERTSTFPAPFQQEGLDYLARFNPLRE
                     DSTRNYICYLLPFWLQELTGLPPETCRRLSLGNVFVMAHYLIQDDVMDTAADNRKTQLA
                     LSQLFYTECLSVYRDLFPATSPFWSYARTYVDEWAVSVISEGTEDYFQGEKNKVALKAS
                     PLKMAGTGALLLAGRADLIQNITNMTDLALLVLQMSDDWADWSEDLVEHSYNCLLSHIS
                     AEQKTAYCEGLGPKQIQEAIYVRGALASYVNIADQAVQQLETLEPSIHGLHSFAHSIAA
                     ELGEVAAEIEGGRSHLRRGGLDYWLSKNMK"
     misc_feature    11320..11332
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.58"
                     /tool="antismash"
     misc_feature    complement(11343..11357)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.42"
                     /tool="antismash"
     gene            complement(11426..12499)
                     /locus_tag="JYU28_RS04575"
                     /old_locus_tag="JYU28_04595"
     CDS             complement(11426..12499)
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369725.1"
                     /locus_tag="JYU28_RS04575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04595"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_039269442.1"
                     /transl_table=11
                     /translation="MFIAKAGKWTAIMSITLSLFTGSLVISSNQALAADCSSGYVALTF
                     DDGPNPSNTKALLSALKQNGLRATLFNLGQNAQNNPSLVRDQQAAGMWIGNHSWSHPHM
                     TQLSTSQMSSEITRTQQTIQSITGTAPKLFRPPYGETNATLKSIETQNGLTEVLWNVDS
                     QDWNGASTAQIVAAAGKLKNGDVILMHDQYQTTLQAIPQIAQNLKNRNLCSGMISPSNG
                     RAVAPDGGNGETPPNKGTKVEAENMTKGGQYTSNISSPFNGVALYSNNDSVKFTQNFTS
                     GTHSFSLRGASNNSNMAKVDLKIGGQTKGTFYYGGSSPAVYTLNNVSHGTGNQEIELVV
                     TADNGTWDAYIDYLEII"
     gene            complement(12582..>12824)
                     /locus_tag="JYU28_RS26380"
                     /pseudo=""
     CDS             complement(12582..>12824)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018932277.1"
                     /locus_tag="JYU28_RS26380"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="SKRTSKTISVSEHFKKWEYMDKMYEDSLTVERYQSSRSANVTSNT
                     ITIGGNNGTRNQEIELVVIADDGTWNAYVDYLEIN"
     misc_feature    complement(12941..12952)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.16"
                     /tool="antismash"
     misc_feature    13005..13023
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.12"
                     /tool="antismash"
     gene            13218..13688
                     /locus_tag="JYU28_RS04580"
                     /old_locus_tag="JYU28_04600"
     CDS             13218..13688
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821363.1"
                     /locus_tag="JYU28_RS04580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04600"
                     /product="hypothetical protein"
                     /protein_id="WP_069010367.1"
                     /transl_table=11
                     /translation="MKKQWKLTAAILYGGVMMYGTAGAAGASGTEPGNSLQAITPNASI
                     QGAARQWNAEPQDEHGHVHRHRHGKRPGGLNHHLNEKVAKLLGITPVQLEKELGQGKSL
                     AEVAKSKGIKEDQLIDKLKNEMTVDLKRLVNRKGPITFDRKSGASNEAQLKR"
     gene            complement(13773..14267)
                     /locus_tag="JYU28_RS04585"
                     /old_locus_tag="JYU28_04605"
     CDS             complement(13773..14267)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369727.1"
                     /locus_tag="JYU28_RS04585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04605"
                     /product="hypothetical protein"
                     /protein_id="WP_029516121.1"
                     /transl_table=11
                     /translation="MNDKLKGLLVGLTIGMMITGATAMAASGTSVNAVVKKFDVFLEGT
                     KKNTADGLIYNGNTYISVKDIGIAESRQISLIDNKLYLGKQQKMITENQALHILSDKIK
                     KDAVKYNLNLMVEGLEGTKYCIRVYEDFPDHIATYGFYYVDKYTSKVTKYDIAQDKEVE
                     I"
     gene            complement(14360..14866)
                     /locus_tag="JYU28_RS04590"
                     /old_locus_tag="JYU28_04610"
     CDS             complement(14360..14866)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821362.1"
                     /locus_tag="JYU28_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04610"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_069010368.1"
                     /transl_table=11
                     /translation="MKSHVLIYDGYVSFEIMLATYFMKTKGDIVTIGVTKDPVISYEDF
                     KVTPSVALDEVSAEDIQLLIIPGGDNTLLKTNKQLLALISTLNNDHKVIATICSATELL
                     EIAGVSYKNPVNHPTGLEIHKNIITAKPNQYVDFAIEIGKVMNIYTDDEDLKETIDFFK
                     LFKDN"
     gene            complement(15037..15504)
                     /locus_tag="JYU28_RS04595"
                     /old_locus_tag="JYU28_04615"
     CDS             complement(15037..15504)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369729.1"
                     /locus_tag="JYU28_RS04595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04615"
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="WP_069010369.1"
                     /transl_table=11
                     /translation="MEGEDHLKNTGMTRPLDTLGRIVIPKEMRTSMGIQAGESLEFYLD
                     VETGLLSMRKYIGVCCHLCYSVRDLSYFRGSFLCKKCINDLKGNIGVSQIPVPVIKEPA
                     CKEKSVHRLSSQHLVEKLRRLMHEHPNAKQGEYAERLGVSQGRISQLKKLL"
     gene            15703..17100
                     /locus_tag="JYU28_RS04600"
                     /old_locus_tag="JYU28_04620"
     CDS             15703..17100
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821361.1"
                     /locus_tag="JYU28_RS04600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04620"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_069010370.1"
                     /transl_table=11
                     /translation="MEITPTIQAEIQTYLKRKGLTMTKFGHTIDLNVGTVSSIVTGNRS
                     ISVHQLDSITAGMNLPPDYFYERYIEECIEESPLNWKKISPFLYRCIELGRLDCLQRVV
                     ILLLDNPNYPPSLFEVAENVYKDGYNEAAAYLYKKVAESEKQQHSERLAVCQYRLFQIN
                     IGQDRAVNLQAAIEFAPFVDRLDEIEQLDALKDLANVYRSLSMWDKVYEFAHQMGQLGQ
                     IQYNLVHNSKRKGTDSKKKPIRPFFTYIAYSDLMCASACDARGDHEQALEHIHCYADLS
                     WVKEQDSESLYWKKQYLQWAKINTYVNRLMSGDISVLPDYVEHMAAEKEIFAELLNVLE
                     VANRYNVDVDHILRRFESQIAAYQEPSSSDTYTQQVLSEEYVRFWYKMAKYSLNKGRYP
                     YGFNCLINAFEKAVTINHVLLIANCFGLFYHFKLHAAPKTQARFQSIYEEVWEKNDQKD
                     GFLLSGN"
     gene            17339..>17521
                     /locus_tag="JYU28_RS04605"
                     /old_locus_tag="JYU28_04625"
                     /pseudo=""
     CDS             17339..>17521
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280170.1"
                     /locus_tag="JYU28_RS04605"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04625"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNRDKTETLIQQMEHARQHLHDLYAEYGFGHACVLEQSMLLDELI
                     NQYNRMYQTRKQPHHV"
     gene            complement(17790..19016)
                     /locus_tag="JYU28_RS04610"
                     /old_locus_tag="JYU28_04630"
     CDS             complement(17790..19016)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309078.1"
                     /locus_tag="JYU28_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JYU28_04630"
                     /product="acyltransferase"
                     /protein_id="WP_069010371.1"
                     /transl_table=11
                     /translation="MSKPRIAEWTELRGLAYLAVVLQHCIGEYIYRSDIQQPDSVMLAM
                     LYHLTRFGTPTFVFLSAALLFYNGNKPIGYPRYIGRRFRDIYVPFLCWTVIYWVCTQNW
                     STAQWGNIYFYKGMFEEMIIPVSGYHLWFVVMIFQFYILFPLFSKAAGQVQAFLRRYST
                     KRRKQLVLAVMLIAAAAYALLLQWSYYDMSAWSTGLPSFWQTLLDYRTYNFVMYFFYFM
                     LGAVCAYMTDTWRGLAQQTLPWNVFVFIGLFMLMGHTMLIQSGVTINLNISTYLKPSTF
                     VLIVSQLLLLYGLLLHLQKDTRSEPFRRMLNWIGRYSFGGYLAHALVLSFISYYTRPLA
                     LGDHHFTATLITFVVVASVSLGISWLFAHLPGGNWIVGSKGRQRLNWHAFRFQFLSSKR
                     ASKSTQELG"
     misc_feature    complement(19780..19796)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.9"
                     /tool="antismash"
     misc_feature    19991..20005
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.25"
                     /tool="antismash"
ORIGIN
        1 agcagcatat tgaccgtcga ggtagtccgc atcggcaacc atgatgaaaa attgcgatcc
       61 ggccgaatcc agatccgctg agcgggccat ggataatacg ccacgtgtat gtttgagtgt
      121 attgttaaca ccattgctct tgaattcgcc tttgatactg tagccggggc cacctgtacc
      181 gttaccttgc ggatcaccac cctgaatcat aaagcctggg atcacacggt ggaaaatggt
      241 gccgttatag gctccctttt gtaccaaaga aatgaaattg ttaaccgtgt tcggtgctac
      301 ttccggatac agctcaagct taattttctt gccatcattc atgacaatcg tgacaatcgg
      361 atgggaaaca gccttgttct tgtctttagt cgcagcagga gttgaagtgc ttgtccggct
      421 ggcagcttcc acatcggccg cttttgtacc gcatccagca accagcacga gcatgatggc
      481 cagtaggcac agcgtgtacc atgggcgtat cgtttttcgg ttcattgata ttcctcctga
      541 aaggttggat ggtgtaacat cctaatttaa agtttggggg cagcgcagaa cacttttcca
      601 ttttctatca tacctttttt gctggggata aggaaatacg ggtttgaaag ccgtattctt
      661 gacccatact gctgctattc ccaaggaaag gggcaggatc atgatggagg tagacaaaaa
      721 gctggcaaaa ggtctcatat ggggtatggc gttcagtctg ccggtttggg taggggtgct
      781 gtactcagta caacatattc gtgactggct ataacataaa gcgtaaagat aggccaaaac
      841 cgttatggtt ttggcttatt tgtatttgtg ccagtccaaa ttgctgttat tcagcagatg
      901 ctcaaagttg ttatctagct tcttctgttc agcttttttt gcttcgacgg cacgctgccg
      961 ttcgtcttct ttacgcttgt cctgttctgc ttgggcttca ttggcttgag ccttaagctt
     1021 attcagcaca tcctgactca acagatcctt taacgtagca ggtttgtcct gaggcgcagg
     1081 agcaggggaa gacgaatttc ttttcttagc catgtcatca tctccattcc attcgattat
     1141 atcagcttct tcacggttgt tccacgatgg aaggatgagg ggggcggtag acttttctaa
     1201 ttgagggggt aataatggaa tgagcagaag ggacgtgtgg catcatgcat ctatattgga
     1261 agcgaaacct ggtcattttg tggattggcg tgttgttttg cagcatggcc tattccgtgt
     1321 ctattccgtt tttacctatt tttctgaata cggaaatggg cgtaaatgat catttggaac
     1381 tgtggtcggg gactgccttt ggagtcactt ttttagccag tgcgctgatt gccccatttt
     1441 ggggttcgct tgcagataaa tatggacgta agccgatgct gattcgttca ggctttagcc
     1501 tggcggtgtt gtacctgata tgtgcctttg tgacagatcc atatgtgttc gtaggagtac
     1561 gactgtttca aggtcttcta tccgggttta ttcctgctgc gattgcgctg gtcggaacgg
     1621 gttcgccaga agagaaaacg ggctatgcgc tcggtataat ggcgaccgct ggggcgacag
     1681 gcagcattat aggcccgttg atcggtggtg tagtgagcca ttattatggc aatcggaatg
     1741 cctttttctt ctctgcagct cttgtactgg tatctgcatt aattgcgacc tttggcgcta
     1801 gagaggacag cttcaaggga acccgtaccc gctcgcatgt tcgtgatgat atcaaggagg
     1861 ctattgctaa ccggccattg tattttttgc ttattttggc gggattaagc accttttctg
     1921 ttatgatact ggaaccatta attacggtat atgtgcttga gatgggagtt gaccgcagcc
     1981 aagcgtctct aagttccgga attgtattct cagccgtagg tattgcggcc gtgctgatgg
     2041 ccccccggtg gggacggatt ggaggacgga ccggatttgc acacgtgctg ctgattgggc
     2101 tgatcggttc gggaatcggg aatattctac aattttatgt aaccaacttc gttggttttg
     2161 gtgcgcttcg gtttggatat ggattgtttt atgcgtccgt tatgcctgct atcaacgcaa
     2221 tgactgtgga ggtcaccaag ccggagtttc gcggacgagc ctttagcttg aatcaatcag
     2281 ccacccaact cgcgaccatg gcggggccgt tgattggcgg catgcttggc agctggatgc
     2341 caatccgctg gatctttgtg ttaaacggtg gcatattgct gcttgcagcg ttgttgctat
     2401 gggccaaggg aaaaaacgtt tttccggttt cagccaagaa gaacgtcacg gatcaggata
     2461 ttcattctgc cggataggag aatgacagca gattgtctaa tggcataagc ttaaggctcc
     2521 tagagcaggt ctttttttgc gcgattagat aattatccca aacctttact tttagtatac
     2581 ttattcataa ccctctacac tgataatatg acaaggaggg atatattatg ataagagacg
     2641 acattttgcg tcaacagctt gagaatgctc gtcaaaagct gtatattttg caagcaaaac
     2701 atggttttaa tcatgccagt gtgctcagac agtctgtaat tatggataac ctcatcaatc
     2761 aatataacca ccttttttat ataaaagaaa aaaaaccgac ggcataaatg taaccgatgg
     2821 gcgagaaact tttggtaagg tcactcgccc ttgtattgta gcgctgatac ttataacaac
     2881 gatgcttgtc ttaacttttc taacagtgtg caatctatca ttttaggtac ggtttgtttg
     2941 atgggcactt agtaaaacac cgataataac gaccaaaccg ccgatgattt ggcgccatgt
     3001 aatcgtttct tgcaaaagca acacagaaaa taagactcca aatatcggaa ccaaattcat
     3061 cagagaaacg gaactgctcg gtgacagctt gattaatccg taattataaa gcaaaaacgc
     3121 gataacggag cagaatacac ccagatatac taacaacata aacgatcctg ttgttggaac
     3181 ctgccaacga tccttttcta atagagccag aggtataaaa aagatactcc ctgcaacggt
     3241 ttgataaaaa gataacgtca cgggtggata tttgtccaca accttacgcg tcataaaagt
     3301 gtaaaacgcc cacgcaaaac ccgttccaat caatattaaa tttccgatga gttgattctt
     3361 actatccgaa ctttcgccta ctgaagtcaa gaaatatacc ccaatcatgg ccagtgctat
     3421 gccgcaaatt ttatatttgg ataatttcac tttatacaaa ataagttcaa gcagcgatgt
     3481 aattgcggga taggatgcaa caattaatgc tgcgttggaa gcggtagtca ggctaacccc
     3541 tatattctcc attgaaaaat agagagtgat tcctaaaaca ccactaaacg aaatcgtagc
     3601 caaatctttt ggctttactt tgacatgttc ttttttaatc agcaaaacga tacctagcac
     3661 tacggaagct ataataaatc tggatagacc caaggtaaga ggggggaacg tcgtgtaggc
     3721 tgctttggtg gcaataaatg atgtgctcca gatcaatagg gccagaatcg tagaaccgta
     3781 gtaaatccgg ttgctttcgc tgtgatgagc tatgacttta ttcaagttga atcctccctg
     3841 aggtaatcct ctgtgaaatg atgatagtag ctactatagt aactactata aaaacgttac
     3901 taaaaagata gtgtgtatat cagtttttgt caaggggaag tgatatagta aggatgaaca
     3961 cgaattgagg agaagacgtc atgaaaccaa aaccaaatat attagaaatt ctacgggatt
     4021 tgaattttag tgaatatgaa gccaaggctt atgtgacctt attggaaagc tctccacttt
     4081 cgggatacgc cgtttcattg aattctgggg taccgagatc caaaatttat gaggttttgt
     4141 ctggaatggt caaccgtggg gatatcatga tcagtcaaga aaatacgcct ctgtatgtgc
     4201 cgcttccgcc gcatgaattg attgcccaga gaaaacgcaa agcagagcag attttcaatg
     4261 tggcgcaaga gagtttggag cagtacacag catcatttca aaacagagaa aatatttgga
     4321 atatttcggg gtatgaagcc attatcaatc gcataaatga aggggtaaag ggagcaaaac
     4381 accggatttt attggagatt tggaaagagg atgccgaggt gttccgagat tccttagggc
     4441 aagtcgctca acaaggaatt gaagtgatca ttgtagcgta tggggagctt aactttgatt
     4501 tcgctactgt ttaccgccat gatatgagtg aggagattac gtctgaaatt ggtggtcggt
     4561 ggattgtact tagcgtagac gaccgggagg tcgttgctgg catactttca cttggtgatg
     4621 acagccgcgc tgcatggacg ttgcatccgg gtctggtgat gccgattacg gaagtgatta
     4681 ttcatgatat ttatatcatg gaaatcctat atgagttccg tgaacaatta gaagagaaat
     4741 tcggccctaa tctaatccat ctccgcaata aatttgctat gggtccgaat ggcaaaggat
     4801 attatattcc tttgactgaa aaaagcatga aacgtgtata gagattgtct gaggtccgat
     4861 gtgcaaaaat aaacaggccc atggagtgtt attccatgag cctaatttta ttggatgttg
     4921 tgttctatta ttttacggtt acaatcacac gttgataatg ctttaaagga tgttttccat
     4981 tgtcctgtac ttctgcaatg atatgaagcg tattccctga cttagcatct gcgggaactg
     5041 tgaaactaac tgcattcgta tcactacctt gcaagtcaat cgtgtttact ttctctcatt
     5101 tttgttcccc actctgaacg ctcctatgat gttttttagg attatgacca tgtaagtatt
     5161 ctttttattc aagatttagg cataaaaaaa acctaaacat atatatgtct caacaatagt
     5221 tgagcatata tacatttagg ttttgcctgc atgatcagtc acaatcctga tccgatttta
     5281 catcaatgtc cgagaaaatg aaagcggttt acaagtccca gcataaaatt agttttacgc
     5341 tttgaataaa ccggattctt tgacttcaga taggaagttg tggaactcag gaatgttcag
     5401 ctgttgctga gcatcggaca aagcgactgc cgggttcgga tggacctcca ccatgatacc
     5461 gtcggctcca gcagccaggg cagctttggc gcaaggggcc aggatgtcct tacggcctgt
     5521 cgagtgagtc acgtccacca atacaggcag atgactttcc tttttcaaaa tcggaacagc
     5581 ggaaatatcc agcgtgttac gcgtccattt ttcgtacgta cggataccgc gttcaatcag
     5641 catgacttgc gtgttaccac gggaaacgat gtattcagca gcatgaagga actcttccat
     5701 tgttgcagcc agtccgcgtt tgagcagaac cggagttctt gtttcacccg cagctttgag
     5761 caattcaaag ttgtgcatgt tacgtgcacc aatttgaata atgtcgatgt attggatcgc
     5821 ttcctccaaa tgtcttggat cgacgatttc actgattgta gccagtccga actcatcacc
     5881 tacacgtttg agaatttgca gtccttccac gcccagtcct tggaaatcgt acggagacgt
     5941 acgtggttta aacgcgccac cacgaagaat cggcacaccg gcttccttga gagccgcacc
     6001 tacttcacga gtttgctggt agctttccac cgagcatgga cctgcgacca tgatggaggc
     6061 tttgccgcct accagcgtat ctttaacctt aataattgtg ctatctggtt gatttttgcg
     6121 gctgacgatc agatgttttt tgtgttcttc tttttgatag ttcaaagaag ccttgaaaat
     6181 atttttgaac agttggcgaa tcgtagcatc gtcaaaaggc ccacggttag ccgcgatcag
     6241 cttgtccagc atttgttgct cacgtaccgg atcaaagtca ggtacccctt gagcttcctt
     6301 caattttcca agttgtccgg ccagttcagc gcgttgggac agcagctcca gcaattgcaa
     6361 atttgtagca tcgagttgtt cacgcagcag ctccaaagaa ttttcatttg tagacataca
     6421 gtactacacc cttcccgaat ttaatttgtt ttttctgtca gtccatggac ttttttgcag
     6481 aaaataacac aaaaaggcac tcgccgcaag ggacgaatgc cgtggtacca ccctaattac
     6541 agaagtatac atacaaatcg tcaacgtcgt tcagtcgaca gcagtaactt ctgagcttga
     6601 tgcccgtaac gggggcttcc ggaaacctct actcggacaa aggaatgaat ccttctgtcg
     6661 gttcaaggct cgactcggga gtgaatttca acgcgggatt gcggtacgct ctcagcaatt
     6721 cgtacctttc tgtgggaatc cattagacgt ttacttgtct ccgtcgatgt ctttgttcat
     6781 ggtattcaaa agatttgacc ttattttaaa caaagtaggt gcagaaggca agccctgatt
     6841 atcaggttca agtttttgcc cttgaattgc tgccctttta ttttccttga tccctgggtt
     6901 cgggattcgc agatgcaact cctcgtgggt tatcttcggt cgaggtatcg tccgtattcg
     6961 tcttgtccgc agtcctacgg tcgtctgctt ccacaggatt cagggcttta taccgtttgt
     7021 attccatatc ggcctgagac atcggatctt tatacatagg agatcagtca actcctttct
     7081 gttatacact acattacccg tatagcagaa taggtaaccg ttttcttcca ttcgttaaaa
     7141 tgagtggtta atccagcata tcgtcgcttt ccagttgatc ttcttcatcc ccatcggtac
     7201 cattcagcaa atcggtacca tgcaggaatt cggcaggagc agaaggatca acgggactgt
     7261 tcggtgtcag ttcatcggca tctggtacgt cctccagagg agtatccggc ccttcggtca
     7321 gattctccca gttggtttct gcattttgca gagaaggctc aaaatcattg tcatgtagct
     7381 cagtagttcg atcgtcacga tttgccatgt tgctcagctc ctttactttt tgttgcttat
     7441 ttcgacctta cccaaacagc ggaacggcta aaccttcagt tagtgtgtct gtaggaagtt
     7501 aaaatcatgc gaatagggag atgcccattc tcaattagcg tttttttggt aactgctgtg
     7561 atatgataaa gaagataggg agggatatga attggaatgg tacatgtttg gtccgatgat
     7621 tagtcgtatc cgcgtaggac aaaaggcatc taccccggga ttttcccgca ccctcattcg
     7681 acgcccggaa ggcttatact ggacagatgg cggacaggcc ggaaaaatag tagaaatacg
     7741 cgattattta ttttccgata tttggacgat ctatgaagat gaagattgtg aaccatggtt
     7801 ggggcttaga gagcagaaag agcggcgcga acaggaaatg atcattaatc aatatgaaga
     7861 ttttacaaaa aatgagtaaa aagaacatga tatccttctt gtgaagaagg tatgcacatc
     7921 atcgtataga ataatataat ttcaggacgt aaaaaatgtt aaaacgtata caaacttgta
     7981 aatcctacta tgtaactttg aggtgcttaa tatgaggcat gtgcccaaag ctgtcgccgc
     8041 cctgctagcg gtcattgtga tgctgttgtc gctgggtcac tccgcctatg cggccaaaat
     8101 gaccccggaa ggggattata aaataccctc ctgggatatg agatggggag aggtagacga
     8161 ggatggctct ttagatgagg taaagaatcc cagcaagatc tggatgcata ttgaagatga
     8221 tacacaactg cttaggcagc ccggcaatat aggctccgcc tggattcgta ttaagttacc
     8281 ttcgctaagt gatgaaacgc cagcgatact ttttgaaaat atttatggca ggcatattac
     8341 gctgtataag gatgggacca atttttacga atcctaccgt gggtacaatt atgagaataa
     8401 tcgtattctg attccgctga agccggaaga cagcggtaaa acattataca tatggacgga
     8461 aagcagtaag aaaagactgg gcatcatcgg taatgtgatg accggtgatt atcgcgattt
     8521 gttggggacc ttggtcagaa tggatgtttt agatattgta ctgggcagta cgtttatctt
     8581 tatcgccctg gtgctgctga tctgctcgtt ttttctgttc cgtccgagta tggccatgtg
     8641 gctgtcccta agtgcgattg tattgtctat tggtctgatg atcgtaacgt attcaccatt
     8701 cttgtataca ttctatcgcg gctatggcaa gctgtactta caactttttg atgtggcact
     8761 atttattctg ctgccctcat tagccttctt ttttgagcaa aacatcaatt cgattatact
     8821 gattcgtaaa ttcagaaagt tgttaaccgc ctactctttg ttctgcttta ccatgatgat
     8881 tgtgaattta ggagcacagg agcggttgaa caacatatat tattttttta gtgtagtcat
     8941 tctgggtata ttactcgtcg ccttaatgat actgctggta tttgcttcgg ttcgcatggc
     9001 acttaagggt gatcacgaag cgatcatctt atcgacaggc tttgcatttt ttgcagtcat
     9061 ctctatcggg gaactgagct ggtttttcat tctggacgga cactacaata tgtttttgtg
     9121 gaaatggggc gtgttcggtt ttgtactggc gttgatcgcg attttgggca gaagactggc
     9181 agaaaagcac aagcaggtgg ttcggtattc cagagaactg gaaatgttca ataatgagct
     9241 tcaacgttcg gagaaaatgg agattattag cgatctggct gcatctgtag ctcatgaggt
     9301 acgtaatccc cttcaagtta cacgtggatt tcttcagttg atgagcaagc aggaggatgg
     9361 taagaacaaa gactatctac atatcgctct ggaggagctg gatcgagctt ccgcgattat
     9421 tactgatttt ctgacctttg ccaagccaga atttgaccaa accaaaacct tgaccatatt
     9481 ggacgaattc aagcatattg aaggaatcat cagtccaatg gctaatttgc aaggtggaaa
     9541 aatttcgctg gatattcccc aggaaatcaa agtacgcggg aattcctcca agttcaagca
     9601 ggcgttcatc aatatcatca aaaacagtat tgaagcgctg cgagaccagg ggcttattca
     9661 tatatgggct tatgtggata acggagaagc tgtcattcat attcgggata atggtgaagg
     9721 gatggatgct cagactttat ccagactagg tgagccttat ttttcgaata agacaaaagg
     9781 cacgggttta ggaatgatgg tgacttttcg gattattgaa acgatgaatg gaaaaataac
     9841 ttttacaagt gcaaaagggg tgggaacaga agcgaccatc cgcttccccg tagccggata
     9901 atatccggct tttttgcgtt cggagaaaac ggagggaagc ttgctgagcc cacccctatg
     9961 aggttaagga atctagatta aataagcatt aacaatcatt ctaccacatt gagcgaggtt
    10021 tctgggatgc agcgagcacg ccggaggggt ctggaggaat taccagaaaa aactgatcag
    10081 gcgtttcttc taatgttttg atttggatat gatcggggat cacgactcct aacacatcac
    10141 gaattgcaga tttgggatca gtcatcagtt tctctctgaa actggcatcc tcccaagctt
    10201 tttgaatgac ttgtgtttga agaacttcag tagccatcaa aaatcaccct ctcattcaat
    10261 tggttatatt tacctagtca gtataccacg aagggctcag aaaaatctag cattatttca
    10321 tatttttgga gagccagtag tcaagtccgc ctcttctcaa atgcgagcgt ccgccttcaa
    10381 tttctgccgc cacttcgccc agctcagctg cgatagaatg tgcaaagcta tgtaggccgt
    10441 ggatagaagg ctccagggtc tctaactgtt ggactgcttg atcggcaatg ttcacatagc
    10501 tggcaagcgc accgcgtaca taaatcgctt cctgaatctg tttgggtccc aatccttcac
    10561 agtaagccgt cttttgctcg gcactgatat gggacaaaag acagttatag ctatgttcga
    10621 ccaaatcttc tgaccaatcc gcccaatcat ccgacatttg aagcacgagt agcgccaagt
    10681 ccgtcatatt tgtaatgttt tgaatcagat cagcacggcc tgcgagcagc aaagcacccg
    10741 ttccggccat ttttaatgga cttgctttca gcgcgacctt atttttttct ccttgaaaat
    10801 agtcctctgt tccttcggat atcacactaa cggcccattc atcaacatac gttcgggcat
    10861 atgaccaaaa aggagaggtt gccggaaaaa ggtcccgata tacgcttaga cactcggtat
    10921 agaatagttg acttaaagcg agttgcgttt tacggttgtc tgctgctgtg tccatcacat
    10981 cgtcttgaat taaatagtga gccatgacga acacgttgcc aagtgacagc ctgcggcatg
    11041 tttcgggggg cagtcctgtg agttcttgca gccaaaatgg aagcaaatag catatgtaat
    11101 tacgcgtgct gtcttcccgc aacggattaa aacgcgccag atagtccaaa ccctcttgct
    11161 gaaagggagc tggaaacgtg gacgtccgtt cctccgcttg acgaaatact ttttccaatt
    11221 cgtctttgta tgcaaaatac cattccatcg ccatcacctg catctcttat gaatattttt
    11281 atagcgactt ctagttgtta cccgccatta tacaacagat tgcaattttc aagattttgt
    11341 tatttttaca ttgagaatgt tgtaaaaagg atatcgacaa aaatcccggt tgggaagatc
    11401 ccgccgggat tttgtttttt ttaaattaga tgatctctaa atagtcaata taagcatccc
    11461 atgtcccatt atcggctgtt acaacaagct caatctcttg atttccggtt ccatggctga
    11521 cattgtttaa agtatagacc gcaggactgc tcccgccgta gtagaaggta cccttcgttt
    11581 gtccaccaat tttcaagtca actttggcca tgttggaatt atttgaagca ccacggagtg
    11641 aaaaactatg ggtgccgctg gtaaaattct gtgtgaattt cactgaatca ttgttggagt
    11701 ataaagccac tccgttgaac ggcgagctga tatttgaagt atactgaccg cctttggtca
    11761 tattctctgc ttccactttt gtgcctttgt ttggcggcgt ttcgccgttt ccgccatcag
    11821 gcgctaccgc ccggccattg cttggtgaga tcataccaga gcaaaggtta cgatttttga
    11881 ggttctgtgc aatttgtgga atagcttgga gtgtagtctg gtactgatca tgcatcagga
    11941 tcacatcgcc gtttttaagt ttgcccgcag cagctacgat ctgtgcggtg gaggcgccgt
    12001 tccagtcttg ggagtcaacg ttccacaata cttcggtaag accgttttgg gtctcaatgg
    12061 atttgagggt tgcgttggtc tcgccatacg gaggacggaa caactttggt gccgtgccag
    12121 taatggactg tatcgtttgc tgcgtgcgtg taatttccga tgacatctgc gatgtgctca
    12181 gttgtgtcat atgcggatgt gaccatgaat gattaccgat ccacatgcct gctgcttgct
    12241 ggtcacgtac aagcgaagga ttattctgcg cgttttgtcc aagattaaag agcgtcgcgc
    12301 gtaaaccgtt ttgcttcaga gcactaagaa gcgctttggt gttagaggga ttgggaccat
    12361 cgtcgaaggt taacgctaca taaccgctcg agcaatcagc cgcaagcgcc tggttgctcg
    12421 agatcaccag cgagcctgtg aataaagaca aggtgattga cataatcgcc gtccattttc
    12481 ctgctttagc tataaacatg ggtctacctc ctagctattt taatatagta tggatgttcc
    12541 gatactccga accgattcaa ctctttacta gatttgaaat tttagttgat ctccaaataa
    12601 tcaacataag cattccatgt tccgtcatcg gctattacaa cgagctcgat ctcttggttt
    12661 ctggtgccat tattgccgcc aatcgtaatt gtattactag ttacattggc actccgactg
    12721 ctttggtatc tctctacagt aagtgaatct tcatacatct tgtccatgta ttcccacttt
    12781 ttgaagtgct cgctgaccga tatggttttg ctcgtgcgtt tggatgtcca caaaaataac
    12841 cttatttttt tgtttcattg gacttttctc ctgtagcctc actatgatgc agtgcattct
    12901 gtagtagctt gatgcaacat gtctttccaa aaatcgaatt gtaaacgttt gcaattcgat
    12961 tttatcatat tttctttaat atataacttg aaatttttca agttatattg tagaaagtat
    13021 agttattcat tcttgctcac tctacaggat agggttccca aggagcgcgt gtagatcgaa
    13081 ggttgggtgt aattgtgata gcaatgttca taatttcttt tttcccgtct tatggttact
    13141 taacaggcga aaatatgaat aaaaatagcg ggaaaagaaa atattatttt aaaaaggatg
    13201 aaagaagggt ctgcaacatg aaaaaacaat ggaaactgac cgctgctatc ctgtatggag
    13261 gagtgatgat gtatggcact gcgggtgcag ctggagcttc cgggacggaa ccgggtaatt
    13321 cgttgcaagc aatcaccccc aacgcctcta tccaaggggc agcccgccaa tggaatgctg
    13381 aaccacagga cgaacacggg catgttcaca gacataggca cggcaaaagg cctggcggct
    13441 tgaatcacca tctcaacgag aaagtagcca agctgctggg catcactcct gtccagttag
    13501 agaaagagct gggacaaggg aagtcgttgg ccgaggttgc taaaagcaaa ggcatcaaag
    13561 aggaccagct cattgataag ttgaagaatg aaatgaccgt ggacttgaaa cggcttgtga
    13621 accgtaaagg cccgattaca ttcgatcgta agtccggcgc ttcgaatgaa gctcaattga
    13681 agcgttagcc ggggataccg tggtatatct gctcttgaat aagtcgagga gtagatcgtt
    13741 tgacaataaa aaaaggatgg ggaaacctat ccttaaattt ctacttcctt atcttgtgct
    13801 atgtcatatt tagttacttt actggtgtat ttatctacat aatagaatcc ataagttgca
    13861 atgtgatcag ggaaatcttc gtaaactctt atacaatatt tagttccttc caaaccttca
    13921 accattaagt ttaaattata tttaacagca tcctttttta ttttatcaga aagaatatgg
    13981 agtgcttgat tttctgtaat catcttttgc tgtttaccta aatacagttt attatcaatg
    14041 aggctgattt gtctgctttc tgcaatccca atatctttaa cagagatata cgtgtttccg
    14101 ttgtaaatca agccatcggc agtgttcttt tttgtcccct ctaaaaatac atcaaacttt
    14161 ttcacaacag catttacgct tgttccagat gcagccattg cggttgcacc agtaatcatc
    14221 ataccaatgg ttaagcccac taatagcccc tttaatttgt cattcatttt aattacccct
    14281 cttatgtatg ctaattccct cactatagta tcctaaatat caccatacat aaagtgattg
    14341 ttgtgggaga gcagaagagt caattatctt taaagagctt aaaaaaatca atggtttctt
    14401 ttaaatcttc atcatcagta taaatgttca tcaccttgcc tatttcaatt gcaaagtcca
    14461 catactgatt tggtttagcc gtaatgatat tcttgtgtat ctccagaccc gttggatgat
    14521 tcacaggatt tttataggag acacctgcta tctccagtag ttcagtggca gaacaaatgg
    14581 tcgctatcac tttatgatca ttatttagtg tactgattag agctagaagt tgcttgttcg
    14641 tctttaatag agtgttatct ccaccaggta taattaggag ttgaatatcc tcagcagaca
    14701 cttcatcaag ggctaccgaa ggcgtaactt taaaatcctc ataggaaatt acagggtctt
    14761 tggttactcc aatcgtaaca atgtcccctt tggttttcat aaaataggtt gctagcataa
    14821 tctcaaaact cacataacca tcataaatta aaacgtgtga tttcatttat acacctactt
    14881 caacattagt ttttagcttt gagtcaatat accactttga taggtttaat tccataattt
    14941 acagcaaata taggcttaga agtttaaata accagtcgca cgaaatcaac cagcgactgg
    15001 ttatttagct ttgctagaat atgagttgag cgatacctat aatagctttt taagctggga
    15061 aatacggcct tgggatacgc cgagccgttc agcgtattcg ccttgcttgg cgtttggatg
    15121 ctcgtgcatg agtcttctta gcttctcaac caaatgttgt gaagacaacc gatgtacact
    15181 tttttctttg cacgcaggtt ccttaataac aggtacaggt atttgactca cacctatgtt
    15241 tcccttcaga tcgtttatgc attttttaca taaaaatgaa cccctgaaat agcttaaatc
    15301 ccgaaccgaa tagcataaat gacagcagac tcctatatac tttcgcatgc tcaataatcc
    15361 tgtttcaaca tccaaataaa attctaaaga ctcaccagct tgaatcccca tagaggttcg
    15421 catctcctta ggaataacaa tccggcctaa cgtatccaag ggacgtgtca tacctgtatt
    15481 tttcaagtga tcttctcctt ccattgtcca acatccaatg atctcctaaa aaaaatataa
    15541 aaatcaataa agtaaaagca tttatgtttg ttccaaaaga tggtattatc gtgaaagaaa
    15601 atcaataatt ataccattag tttccaaact acattgttta ttgaaattga aattgaaatt
    15661 gaaattgaaa ttctatgaaa atgctgaaag ggtggtttat ccatggaaat cacacctacg
    15721 atacaggcag aaattcaaac ttatctgaaa cgaaaaggct taacgatgac caagtttggt
    15781 cacacgattg atttgaatgt aggtacagtt agtagcattg tgactggtaa ccgatctatt
    15841 tctgttcatc aactggatag tattactgcg ggaatgaatt taccaccgga ttatttttac
    15901 gaacgttata ttgaagaatg cattgaagaa tctccgctaa actggaaaaa aataagccct
    15961 ttcttatacc gatgcattga actaggacga ctcgactgct tgcagcgagt tgtaattttg
    16021 ctattggata accctaatta tccgccatcg ctctttgaag ttgccgaaaa tgtatacaaa
    16081 gacggttaca acgaagcagc ggcatacctt tacaaaaagg tggctgaaag tgagaagcag
    16141 cagcattcag agcgattggc ggtctgccag tatcgtttgt tccaaatcaa tattggacaa
    16201 gatagagctg taaatcttca agctgccatt gaatttgctc cttttgtgga tcgtttagac
    16261 gagatagagc aattagatgc attaaaagat ttggctaacg tctacaggtc attaagcatg
    16321 tgggacaagg tgtatgaatt tgcccatcag atgggtcaat taggacagat ccaatataat
    16381 ttggttcata actccaagcg aaaaggaaca gattcgaaaa aaaagccaat tagaccgttt
    16441 ttcacctaca tagcctattc tgatctaatg tgtgctagtg cttgcgatgc aagaggggat
    16501 catgaacaag cattagaaca cattcattgt tatgcggatc taagttgggt gaaggaacaa
    16561 gattctgagt ctctctattg gaagaagcaa tatctgcaat gggcgaaaat taatacgtac
    16621 gtcaatagac ttatgtccgg ggacatcagt gttctgccag attacgtaga acatatggct
    16681 gccgaaaagg agatttttgc cgagctactg aacgtccttg aagtagctaa tcgatataat
    16741 gtagatgtag atcatatcct tcgacgcttt gagtcccaaa ttgcagcgta tcaggaacca
    16801 tcatcttctg atacgtatac tcaacaagtt ttatcggaag aatacgtacg cttctggtac
    16861 aaaatggcca agtacagcct aaataaaggc agatatccat atggtttcaa ttgtttaata
    16921 aacgcttttg aaaaagctgt tacaattaac cacgtactac ttattgccaa ctgttttgga
    16981 ttattttatc atttcaaatt acatgcggct cctaaaacac aggctcggtt tcaatccatt
    17041 tatgaggagg tgtgggagaa aaatgatcaa aaggatggct ttctgcttag cggtaactag
    17101 ctttttactg gtattcacag taccatatca aactgcaaac ctaagccatg gcacaatcca
    17161 aacacaagga cacgttggtg gaatgtgatc caagtaatca tcatcttcaa attcattact
    17221 attgaccagc ttatagctgg tctatttttg tattattttg taatttttag gttcaaaaaa
    17281 gatcatgacg tatttgtaca tccctcctta aaataagatt caataggagg tatgcaggat
    17341 gaacagggat aaaacggaaa cgttaattca acaaatggaa cacgccagac aacacttgca
    17401 tgatctttac gcagagtatg gcttcggaca tgcttgtgta cttgaacagt ctatgctttt
    17461 ggatgaactg attaatcagt acaaccgtat gtatcagacc agaaagcagc ctcaccatgt
    17521 tttggatcag atcattaaca acgacgatgt tatgttcagt ccatcctccc ctttctcttt
    17581 atgcaaaact gtgacttctc ccacgtaatg tttattatta ttctatataa tgacttattt
    17641 taaaataaaa tacatattca tgtcataaaa tgttaatcat ttttttgggg acagcatact
    17701 aaggcaacaa aaaaagcaga gctccataag agagccctgc caaagtccat tggatttata
    17761 accccatgct gaaacacaga cgcacaagtt tagccaagct cctgcgtgct tttggaagcg
    17821 cgcttagagg aaaggaactg gaaacgaaac gcatgccagt tcaaccgctg tctgcctttg
    17881 gagccaacaa tccagttgcc gccgggcaga tgggcaaaga gccagctgat gcccagagaa
    17941 acacttgcca cgacgacaaa cgtaatgagc gtagctgtaa aatgatgatc acccagtgca
    18001 agcgggcggg tgtagtagga tatgaaggac agcacgagcg catgggccag atatcctccg
    18061 aaggaatagc gtccaatcca gttcagcata cggcgaaacg gctcggatcg cgtatctttt
    18121 tgcaaatgaa gcagcagtcc gtacaacaaa agcaactgcg agacaatcag cacgaaggtg
    18181 cttggtttca gataagtaga aatattgaga ttgatcgtaa cacccgactg gatcagcatc
    18241 gtgtgaccca tgagcatgaa caaaccaata aagacaaata cattccacgg caacgtctgt
    18301 tgggccaatc cccgccaggt gtccgtcata taggcgcaca ctgcgcccag cataaaatag
    18361 aaaaaataca taacaaagtt ataagtgcgg taatctaaca gagtctgcca aaaggacggc
    18421 aacccagtgc tccatgcaga catgtcatag taggaccatt gtaacaacaa agcgtaagcc
    18481 gcagcggcaa tcagcataac agccaaaaca agctgtttgc gtcttttcgt gctgtaacgg
    18541 cgtagaaacg cttgaacctg cccggctgct tttgaaaata aaggaaacaa aatataaaac
    18601 tgaaagatca tcactacaaa ccatagatga tatccgctga cggggatgat catttcctcg
    18661 aacatacctt tgtaaaaata aatatttccc cactgcgccg ttgaccagtt ttgagtacat
    18721 acccaataaa taaccgtcca gcagaggaaa ggaacataaa tatctcgaaa ccgcctgcca
    18781 atatagcgag ggtagccaat cggtttgtta ccattataaa aaagcagcgc cgcagacagg
    18841 aaaacgaacg tcggtgtgcc aaaacgtgtc aaatgataca gcatcgcgag catcacagaa
    18901 tctggctgtt ggatgtcgct gcgataaata tattcgccaa tgcaatgctg aagcacgaca
    18961 gcgaggtagg cgaggccccg tagttctgtc cactccgcga tacgcggctt gctcatccat
    19021 atcactcctt ttcctcaaga tacgcacatg tttttcctag cgcaattgta ggtattgtaa
    19081 cgtagaaaca ttagtgcagg attaacgcca cctgaaagta agaagagtga agtagttcca
    19141 atttaatatg attgcgttta caatctaagt gaaaccagaa taaattaaag tgaatttata
    19201 acttaaggat acacacagga agagggagga aggatgaaaa aaacgctgct ggtatatatg
    19261 ctgttgattg cggcctttgc tctctatgtg ttcaggtatg aacaaactgg cccgttgaat
    19321 ggtacttggg aagataaggg gctacgaggc agcatcggag aaacctatat gatgattacc
    19381 ttccagtctg gcttggagta ttggaaaagc gggctcaagg gtttcgagga tgcaggagat
    19441 gctttgggag tgactgtgga gtatcgggga gctacccgtt atgatgcaca ggagcagacg
    19501 acagttattg agcaggcgat tgctcgtaag cccgcaggga ttgccatatc agcgattgat
    19561 cctcactctc tgattccggt aattaataag gcgctggatg cgggcattcc tgtggtactg
    19621 tttgatgccg aagcgccggg gagtcgggcg tattcttttt tgggcacgga taattataag
    19681 gcgggcgtga ccgctgcgga taaaatggca gagctgttgg gacgagaagg tcaagtcgct
    19741 gttttgacgc tacccggtca gcaaaatcat gaggaacgct tgcgtggctt tcgcgatacc
    19801 atacagcggc agtatcctgc catgaaggtg gtggaagtag cggatggccg cgcagacgcg
    19861 atggtctccc gggatgagtc gcaaaggctg atgaaagctt atccgaaact ggcgggcatt
    19921 tttgtgaccg aagcaacggg aggaataggt gtaggtgaag cggtactgag tcaaaaaaac
    19981 agccacccgc tgaaaatcat ttcttttgat acgaataaag cgacattgga tatgattcgt
    20041 ggtggcacaa tctcggcaac aattgctcag ggaacatgga atatgggcta ttggtcgctt
    20101 caatatctgt tccatctgca tcatcatttg acgactcctg cgccttcttc caccggagac
    20161 aacactccgc tgcccgtgcg ggtagacact ggaatctctg ttgtcaccca ggcgaatgta
    20221 gatgattatt atgcgaa
//
