LOCUS       NZ_CP071839            12847 bp    DNA     linear   CON 20-APR-2024
DEFINITION  Streptomyces cyanogenus strain S136 chromosome, complete genome.
ACCESSION   NZ_CP071839
VERSION     NZ_CP071839.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces cyanogenus
  ORGANISM  Streptomyces cyanogenus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8773899)
  AUTHORS   Hrab,P., Ruckert,C., Busche,T., Ostash,I., Kalinowski,J.,
            Fedorenko,V., Yushchuk,O. and Ostash,B.
  TITLE     Complete genome sequence of Streptomyces cyanogenus S136, producer
            of anticancer angucycline landomycin A
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8773899)
  AUTHORS   Hrab,P., Ruckert,C., Busche,T., Ostash,I., Yushchuk,O.,
            Kalinowski,J. and Ostash,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2021) Genetics and Biotechnology, Ivan Franko
            National University of Lviv, 4 Hrushevskoho St, Lviv, Lviv region
            79005, Ukraine
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method :: Newbler v. 2.8; Canu v. 1.8; Unicycler v. 0.14
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 974878.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017526105.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 09:57:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,747
            CDSs (total)                      :: 7,656
            Genes (coding)                    :: 7,375
            CDSs (with protein)               :: 7,375
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 281
            CDSs (without protein)            :: 281
            Pseudo Genes (ambiguous residues) :: 0 of 281
            Pseudo Genes (frameshifted)       :: 129 of 281
            Pseudo Genes (incomplete)         :: 239 of 281
            Pseudo Genes (internal stop)      :: 25 of 281
            Pseudo Genes (multiple problems)  :: 104 of 281
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:56:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7518744
            Orig. end                         :: 7531591
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071839.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Bohdan Ostash, 4
            Hrushevskoho St., Lviv, 79005, Ukraine.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12847
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="31"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12847
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12847
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7847](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7847)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            complement(139..669)
                     /locus_tag="S1361_RS33735"
                     /old_locus_tag="S1361_33715"
     CDS             complement(139..669)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="S1361_RS33735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33715"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_208036885.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.6e-25, bitscore:
                     87.3, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPPAKVRQLKQAGTPVVAASISLGGGRTPPPARTTRKPAIDNVS
                     NAGVATVVAAGNNGYGDVVSAPACVSSVIAVGATTDDDQLSAFTNRAPVPDVFAPGTGI
                     VSSVPGGGYASRNGTSMAAPHVSGALAVLRQAFQAVGTAPRSRRRSWWPVSPAARRRPC
                     RWRWVSPTSGWVM"
     gene            complement(690..2099)
                     /locus_tag="S1361_RS33740"
                     /old_locus_tag="S1361_33720"
     CDS             complement(690..2099)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018549496.1"
                     /locus_tag="S1361_RS33740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33720"
                     /product="amino acid permease"
                     /protein_id="WP_208035658.1"
                     /transl_table=11
                     /translation="MHSTGTVPAPAPAEIPAESPTVPAGDPHGDTGRHARRFGLPVATA
                     LVMGNIIGGGIFLLPASIAPYGTVSLVAFGVLTVGAIALALVFGRLAARDPRTGGPYVY
                     AREAFGDFAGFLAAWSYWITTWVSNAALAVAAVGYLDVLIPVNGHRWTACLAALTLQWL
                     PALANFAGTRYVGAVQLVSTVLKFVPLLLVAVGGLFFFDPDRLGPFNASGQGAIGAVSA
                     SAALLLFSYLGVESAAVSAGEVRNARRNVGRATVIGTAGAALVYLLGTLSVFGTVAHDR
                     LVTSTAPFSDAVNAMFGGSWGGTAVALAALVSMTGCLNGWTLLSAQTPYAAARDGLFPS
                     AFTRRRRGVPTVGVGVTVVLASLLTVYNYFSGSGKVFEVLVLVTTFTATVPYLLAAAAQ
                     IFHLVTGRPETVDRARLVRDSVITAVAAVFTLWLMAGAGYAAVYQGALFLFAGVLVYAV
                     MAARRQRKQAR"
     misc_feature    complement(2117..2131)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.7"
                     /tool="antismash"
     misc_feature    complement(2171..2184)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.3"
                     /tool="antismash"
     gene            complement(2297..2992)
                     /locus_tag="S1361_RS33745"
                     /old_locus_tag="S1361_33725"
     CDS             complement(2297..2992)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676290.1"
                     /locus_tag="S1361_RS33745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33725"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_208035659.1"
                     /transl_table=11
                     /translation="MRDMAQNTRDTELPALPRLGGRRSSYRERVADALRAALIAGELRP
                     GEVYSAPSLAARFGVSATPVREAMLDLVKEGLVDTVPNKGFRVTAVSDRQLDEYTHIRA
                     LIEIPTVVELARTADRVSLEALRPAAREIVTAAVAGDLIAYVEADTRFHLGLLALAGNA
                     HLVEVVADLRKRSRLYGLTALVEAGRLLASAEEHLELLDALLERDEKAVHAIMTRHLGH
                     VRSLWAATD"
     misc_feature    2978..2988
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.05"
                     /tool="antismash"
     gene            complement(3015..4016)
                     /locus_tag="S1361_RS33750"
                     /old_locus_tag="S1361_33730"
     CDS             complement(3015..4016)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358096.1"
                     /locus_tag="S1361_RS33750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33730"
                     /product="proline racemase family protein"
                     /protein_id="WP_208035660.1"
                     /transl_table=11
                     /translation="MRSKLVLHAVDSHTEGMPTRVITGGIGTVPGATMNERRLWFREHR
                     DGVKQLLMNEPRGHAAMSGAILQPPTRPDCDWGVLYIEVSGYLPMCGHGTIGVATVLVE
                     TGMVEVTEPVTTIRLDTPAGLVVAEVAVENGAARNVTLRNVPSFAAGLDRKIALPDGRT
                     VTYDLAYGGNFYAILPLDAFGLPFDRARKDDILAAGLSLMAAINAEAEPVHPEDPSIRG
                     CHHVHLYAPGATARHSRHAMVIHPGWFDRSPCGTGTSARMAQLHARGELPLHTEFVNES
                     FIGTRLTGRLLGTTEVAGVPAVLPSFTGRAWITGTAQYLLDPTDPFPEGFVL"
     gene            complement(4029..4925)
                     /locus_tag="S1361_RS33755"
                     /old_locus_tag="S1361_33735"
     CDS             complement(4029..4925)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069839.1"
                     /locus_tag="S1361_RS33755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33735"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_208035661.1"
                     /transl_table=11
                     /translation="MTDPQHRPWRGILVATAVPLRDDLSVDHDRYAEHCAWLVANGCDG
                     VVPNGSLGEYQVLTPEERARVVETAVAAIGGARVMPGVSAYGSAEARRWAEQAAEAGCA
                     SVMLLPPNAYRADERSVLAHYTEVARAGLPVVAYNNPIDTKVDLVPELLARLHGEGLVH
                     AVKEFSGDVRRAYHIAELAPELDLLIGADDVLLELAVAGAKGWVAGYPNALPRASAELY
                     RAALAGDLTTALPLYRQLHPLLRWDSRTEFVQAIKLSMDVVGRYGGPVRPPRVPLPPEQ
                     EAAVRAATEKAVAAGLA"
     misc_feature    complement(4948..4958)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            complement(5001..6395)
                     /locus_tag="S1361_RS33760"
                     /old_locus_tag="S1361_33740"
     CDS             complement(5001..6395)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676293.1"
                     /locus_tag="S1361_RS33760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33740"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_208035662.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.4e-26, bitscore:
                     92.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 2.4e-11, bitscore:
                     42.7, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAERPRLAVVGAGPAGLAGALAAAARGVEVVLVDAAEQAGGQFYR
                     QPARALGARRPQALHHQWRTWERLRDALDRHREAGRITHLTDHHVWCVRRGSACDEVTV
                     HALRGPAQEEGVTVRADAVLLATGGYEQVLPFPGWTLPGVVTAGGAQAMLKGGLVLPGR
                     TAVVAGTGPLLLPVATGLAAAGARVAALVESAAPAALLRRAPALAAEPGKLAEGAGYAA
                     RLLRHGVRTLARHTVVAAHGTDRLEAVTVAALAPDGRLRPGTYRRIPCDTLAVGHGMLP
                     HTDLAETLGCTLSGTAVQVDGEQRTDVPGVWAAGEATGVGGAALALAEGHIAGRSAAAR
                     LHGTVPDPRRWGAAARARTRLREFATALDAVYAPPAGWADRVPDDTVVCRCEEVTAGQV
                     RASADTLGAGDLRTVKLLTRAGMGWCQGRMCAPAVAGLTGCPLTAGRPFARPVPLGVLA
                     ALPETD"
     gene            complement(6388..6690)
                     /locus_tag="S1361_RS33765"
                     /old_locus_tag="S1361_33745"
     CDS             complement(6388..6690)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994282.1"
                     /locus_tag="S1361_RS33765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33745"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_208035663.1"
                     /sec_met_domain="Fer2_4 (E-value: 2.2e-28, bitscore: 96.9,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPLELTRARPGEACTVTFDGRPLTALPGQTVAAALWSAGVTAWR
                     STRGTGRPRGVFCGIGVCFDCLVTVNDRPNQRACLVPVRPGDVIRTQEGTGRDDG"
     gene            complement(6687..7847)
                     /locus_tag="S1361_RS33770"
                     /old_locus_tag="S1361_33750"
     CDS             complement(6687..7847)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676295.1"
                     /locus_tag="S1361_RS33770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33750"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_208035664.1"
                     /sec_met_domain="DAO (E-value: 1.3e-62, bitscore: 211.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKRLTCDVVVVGAGMVGAACALYAARAGLDVRLVDRGPVSGGTT
                     GAGEGNLLVSDKEPGPELELALLSARLWAELAHQHGTAFEYEPKGGLVVASAPEALAAL
                     REFAAAQRGAGVTAVPVDARRLAELEPHLAPGMAGGVHYPQDAQVMPALAAAHLVRASG
                     AALDTGRTVTGVLRTADGAVYGVRTDRGEIHAPAVVNAAGTWGGEVAALAGVRLPVLPR
                     RGFVLVTEPLPRMVRHKVYAADYVADVASDSAALRSSPVVEGTAAGPVLIGATRERVGF
                     DRSLSLPAVRALAAGAVGLFPFLERVRALRTYAGFRPYLPDHLPAIGADPRAPGLFHAC
                     GHEGAGIGLATGTGQLIAQALTGKAPELDLAPFRPERFDTEGGDVR"
     misc_feature    7849..7865
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.15"
                     /tool="antismash"
     misc_feature    7853..7863
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            7988..8110
                     /locus_tag="S1361_RS39940"
                     /old_locus_tag="S1361_33755"
     CDS             7988..8110
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019060122.1"
                     /locus_tag="S1361_RS39940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33755"
                     /product="putative leader peptide"
                     /protein_id="WP_279577637.1"
                     /transl_table=11
                     /translation="MARLQTGTGSTSRTPLRAPLLTSRRHIDLQRVCSAISRHR"
     gene            8191..9078
                     /locus_tag="S1361_RS33775"
                     /old_locus_tag="S1361_33760"
     CDS             8191..9078
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676296.1"
                     /locus_tag="S1361_RS33775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33760"
                     /product="glutathione S-transferase C-terminal
                     domain-containing protein"
                     /protein_id="WP_208035665.1"
                     /sec_met_domain="GST_C (E-value: 9.2e-05, bitscore: 21.4,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSITPLAAVPSARRAAPVFRGRIGRDPRSGHYAVPHRYRLHLSTA
                     CPDGLRLAVGHSLLGLDTSCPVTLLPPVPDRPGGGHSALRPLYEASAHHYTGPALAPVL
                     SDDWSGRIVSTHTPDILRDLDRFGPGDRARLYPTGLESVIEAVERMCAEGIEEAAQRAG
                     RAGADPAERAAALDTLLDTLGRLERRLSGEEYLADDRLTAADVELWVTLVQLDTVHRCH
                     LDASAVHRIADHRALWAYARRLAARPAFGRHLDLDGIARRHHGRCQGLEAAGAAVQILD
                     WAGHAADTPDASRR"
     regulatory      9156..9266
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00634"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00634"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class IV; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            9299..9448
                     /locus_tag="S1361_RS33780"
     CDS             9299..9448
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="S1361_RS33780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_208035666.1"
                     /transl_table=11
                     /translation="MYAAPRTATSRPQGCVPSYAGLLVADRAVDLLRVNSALCTAPGSA
                     RCQG"
     gene            9621..10601
                     /locus_tag="S1361_RS33785"
                     /old_locus_tag="S1361_33765"
     CDS             9621..10601
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676297.1"
                     /locus_tag="S1361_RS33785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33765"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_208035667.1"
                     /transl_table=11
                     /translation="MSEPPGAAVSLAEAPPAASPPKSLTAQRVQPLRRPGRWIVTAVVL
                     VLVAQILHGLATNPFYQWARFRYWFLRPTILDGLVVTLEVAALSAVLGLLGGILLALGR
                     LSGSPVLRAVSWTYTWLFRSVPLIVVLIFLYNFSALYKTLSLGIPFGPAFVSFDESKLA
                     TDMTVAVIGLGLNEAAYAAEVVRGGILSVDQGQHEAAAALGLPRGYQFTRIVFPQALRS
                     ITPNYVNQLIGLVKSTSLVFYVSLLDLFGSVQTMGSTYPGDIVPLLLVATVWYLILTSV
                     VSVVQFYVERYFARGATRSLPPTPLQKARAGLADFRARLRREAAV"
     gene            10598..11398
                     /locus_tag="S1361_RS33790"
                     /old_locus_tag="S1361_33770"
     CDS             10598..11398
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359792.1"
                     /locus_tag="S1361_RS33790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33770"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_208035668.1"
                     /transl_table=11
                     /translation="MTATATATATPETAPAALEVHDVHKWYGTHRVLDGIDLTVRPGEV
                     TAILGPSGSGKSTLLRVINHLEKPEIGYVSVGGELIGVKRNGGRLKELSERTILTQRSR
                     IGFVFQNFNLFPHLTVLDNVAAAPVATGRLNKPEARELARELLTRVGLGDRTGAYPRQL
                     SGGQQQRVAIARALALRPGIILFDEPTSALDPELVGEVLSVIKDLATSGTTLVIVTHEI
                     GFAREVADRVVFIDGGRIVEQGPPSQVLDKPRHERTRDFLSKVL"
     gene            11486..12505
                     /locus_tag="S1361_RS33795"
                     /old_locus_tag="S1361_33775"
     CDS             11486..12505
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676299.1"
                     /locus_tag="S1361_RS33795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33775"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_208035669.1"
                     /transl_table=11
                     /translation="MRSHFSRRSLIRGITAATTVATLATGLAACGGESDAATTTDAAGT
                     VTVGRVSNGAAKQTELKVSEVKSLNAELPAAIRKSGTLRIGVGALPDGFPPLAYIGGDQ
                     KTLTGAEPDLGRLVAAVLGLKPQFSNATWENMFVGIDSGKYDAAFANITDTEERKKKYD
                     FASYRKDNVGFEVLKKSTWNFDGNYENLAGRTVAVDNGTNQEKILLEWQTKLKKEGKTL
                     TVKHYQSKNATYLALTGGRIDAYFAANPGVAYHITQTAKSPNPTRSAGTFSGAGATLQG
                     LIAATTKKDSGLAKPFADAVNYLIEHGQYAKWLAAYNLSDESVAKSEVNPPGLPLTNS"
ORIGIN
        1 aacgtgtgag ggccggcgcc ggacaggccc gctgcccccc ggcaggcgct gccgggggcc
       61 gcaggcctgg ggggcagaac gtgacgctgg tcgtctgcag gccgtaggtc ctgccgtccg
      121 gggagaccag gtcgatcttc acatcaccca gccactcgtg ggtgacaccc accgccacct
      181 gcaaggcctt cggcgcgctg ccggagaaac cggccaccat gatcggcgcc tcgaccgtgg
      241 cgcggtgccg accgcttgga acgcctgccg gaggacggcg agggcgccgc tgacgtgcgg
      301 ggcggccatg gaggtgccgt tcctggaggc gtagccgccg cccggaacgg aggagacgat
      361 gccggtgccg ggtgcgaaca cgtccggcac cggggcccgg ttggtgaagg cggacagctg
      421 gtcgtcgtcg gtggtggcgc cgaccgcgat gacggaggag acacaggccg gggcgctcac
      481 cacgtcgccg tacccgttgt tcccggccgc gaccacggtg gcgacgccgg cgttggacac
      541 gttgtcgatg gccggcttgc gggtcgtcct cgcaggcggt ggcgtccggc cgccgccgag
      601 gctgatgctg gccgcgacga ccggcgtgcc ggcctgcttg agctgccgta cctttgccgg
      661 tggccggatg ccgggatgcg ctcagcccgc taccgtgcct gcttccgctg ccgtcgggcc
      721 gccatcaccg cgtagacgag gactccggcg aacaggaaca gcgcgccctg gtagaccgcc
      781 gcgtagccgg cacccgccat cagccagagg gtgaagaccg cggccaccgc ggtgatcacg
      841 gagtcccgca ccagccgggc ccggtcgacc gtctccggcc ggccggtcac caggtggaag
      901 atctgcgcgg cggcggccag caggtacggc acggtggcgg tgaacgtggt gaccaggacc
      961 aggacctcga agaccttgcc cgagcccgag aagtagttgt agacggtgag cagcgaggcg
     1021 aggacgaccg tcacgccgac cccgaccgtg ggcacgcccc gccgacggcg cgtgaaggcg
     1081 ctcgggaaca gcccgtcgcg ggccgccgcg tacggcgtct gggcactcag cagggtccag
     1141 ccgttgaggc agccggtcat cgacaccagg gcggcgagcg ccacggccgt gccgccccag
     1201 ctgcccccga acatcgcgtt cacagcgtcc gagaacggcg cggtggaggt caccagacgg
     1261 tcgtgcgcga ccgtgccgaa cacggacagc gtgcccagca ggtagaccag cgcggcgccc
     1321 gcggtgccga tgaccgtcgc gcgccccacg ttgcgccggg cgttcctgac ctcgcccgca
     1381 ctgacggccg cggactccac cccgaggtag gagaagagca gcagcgcggc ggaggcggac
     1441 accgcgccga tcgctccctg accgctcgcg ttgaacggtc cgagccggtc ggggtcgaag
     1501 aagaacagcc cgccgacggc gacgagcagc agcggcacga acttcagcac cgtggacacc
     1561 agctggacgg caccgacgta ccgggtgccg gcgaagttgg cgagggcggg cagccactgc
     1621 agggtcagcg cggccagaca ggccgtccag cgatggccgt tgaccgggat cagcacgtcg
     1681 aggtacccga cggcggcgac ggcgagcgcg gcgttcgaca cccaggtggt gatccagtac
     1741 gaccaggccg cgaggaatcc cgcgaagtcg ccgaacgcct ccctggcgta gacgtagggg
     1801 ccgccggtgc gcgggtcgcg tgccgcgagc cggccgaaga ccagggcgag cgcgatggcg
     1861 ccgacggtca gcactccgaa ggcgaccagg ctgaccgtcc cgtacggggc gatggaagcg
     1921 gggagcagga agatgccgcc gccgatgatg ttgcccatga ccagcgcggt cgcgacgggc
     1981 aggccgaacc ggcgggcgtg cctgccggtg tcgccgtgcg gatccccggc gggaaccgtg
     2041 ggggactccg cggggatctc cgcgggagcc ggagccggga cggttccggt gctgtgcatg
     2101 ggtggtgcgc ctctcatgga actgacgttc ccgggatcac cgggacgggg ccatggtcgg
     2161 ggatgcgccg ttctggcgca aaatcgccgt ttgttgtccc gtgcgggccg cctgggcatg
     2221 gaaaatacgt cgtggcgcgg ccccggcgcc gcgagatgtc cggtcccttc cgtgcggctc
     2281 ctccgggcgg gcgcggtcag tccgtcgccg cccacaggct gcgcacatgc ccgaggtgcc
     2341 gggtcatgat cgcgtgcacg gccttctcgt cgcgctccag cagcgcgtcc agcagctcca
     2401 ggtgttcctc ggcggaggcg agcagccggc ccgcctccac cagcgcggtc agcccgtaca
     2461 gacgggagcg tttgcgcagg tcggccacga cctcgaccag gtgggcgttg ccggccaggg
     2521 cgagcagacc gaggtggaag cgggtgtcgg cctcgacgta ggcgatcaga tcgcccgcca
     2581 ccgccgcggt cacgatctcc cgggccgccg gacgcagcgc ctccagcgag acgcggtcgg
     2641 cggtgcgggc cagctccacc acggtgggga tctcgatgag cgcccggatg tgcgtgtact
     2701 cgtccagctg ccggtcggag acggcggtga cccggaagcc cttgttgggc acggtgtcga
     2761 ccagcccctc cttgaccagg tcgagcatgg cctcccgcac cggtgtcgcc gagacgccga
     2821 accgggcggc cagcgagggc gccgagtaga cctcgccggg ccgcagctcg cccgcgatca
     2881 gcgcggcgcg cagggcgtcc gcgacccgct cgcggtagct gctccgccgg ccgcccagcc
     2941 gggggagcgc gggcaattcg gtgtcacggg tgttctgtgc catgtcacgc atcaccgggt
     3001 gagtctagag gacgctagag gacgaacccc tccgggaagg ggtcggtcgg gtccagcagg
     3061 tactgtgcgg tgcccgtgat ccacgcacgg ccggtgaagc tgggcagcac ggccggcacc
     3121 ccggcgacct ccgtggtccc cagcagccgg ccggtgagcc gggtcccgat gaaggactcg
     3181 ttcacgaact cggtgtgcag cgggagttca ccgcgcgcgt gcagttgcgc catgcgcgcg
     3241 ctggtgcccg tgccgcacgg ggaacggtcg aaccagcccg gatggatgac catggcgtgc
     3301 cgggagtgcc gggccgtggc accgggtgcg tacaggtgga cgtggtggca gccccggatc
     3361 gacgggtcct ccgggtgcac cggctccgcc tccgcgttga tcgccgccat cagggacagt
     3421 ccggccgcga ggatgtcgtc cttgcgggcg cggtcgaagg gcagcccgaa ggcgtccagc
     3481 ggcaggatcg cgtagaagtt gccgccgtag gccaggtcgt aggtgaccgt acggccgtcc
     3541 ggcagcgcga tcttgcggtc cagtccggcc gcgaacgacg gcacgttcct gagcgtcacg
     3601 ttccgggcgg cgccgttctc caccgcgacc tcggcgacga ccagccccgc cggggtgtcg
     3661 agccggatgg tggtcaccgg ctccgtgacc tccaccatgc cggtctccac cagcacggtc
     3721 gccaccccga tcgtgccgtg cccgcacatc ggcaggtaac cggagacctc gatgtagagg
     3781 acgccccagt cgcagtccgg gcgggtcggc ggctgcagga tcgcgccgct catcgcggcg
     3841 tggccgcgcg gctcgttcat cagcaactgc ttgacgccgt cgcggtgttc gcggaaccac
     3901 agccgtcgtt cgttcatggt cgcgcccggg acggtgccga tcccgccggt gatcacccgg
     3961 gtcggcatcc cctcggtgtg cgagtcgacg gcgtgcagga cgagcttgct gcgcatgggg
     4021 gaggctcctt acgcgaggcc cgcggcgacg gccttctcgg tggccgcgcg gaccgcggcc
     4081 tcctgctcgg gcggcagcgg gacccgcggc gggcgcaccg ggccaccgta ccgtccgacg
     4141 acgtccatgg agagcttgat ggcctggacg aactccgtcc gcgagtccca gcgcagcagc
     4201 gggtgcagct gccggtacag cgggagcgcg gtggtgaggt ccccggccag cgcggcgcgg
     4261 tacagctccg cggaggcgcg cggcagggcg ttggggtagc cggccaccca gcccttggcg
     4321 ccggccaccg ccagctccag cagtacgtcg tcggcgccga tcaacaggtc cagttccggc
     4381 gcgagttcgg cgatgtgata ggcgcggcga acatcaccgg agaactcctt gacggcgtgc
     4441 acgagcccct cgccgtgcaa ccgggcgagg agttcgggca ccaggtcgac cttggtgtcg
     4501 atcgggttgt tgtacgccac caccggcagg cccgcccgtg cgacctccgt gtagtgggcg
     4561 agcaccgacc gctcgtcggc gcggtaggcg ttgggcggca gcagcatcac cgaggcgcag
     4621 ccggcctcgg cggcctgctc ggcccagcgg cgggcctcgg ccgagccgta cgcggagacg
     4681 cccggcatca cccgcgcgcc gccgatcgcg gccacggcgg tctccaccac ccgggcccgc
     4741 tcctccgggg tgagcacctg gtactcaccg agcgagccgt tcggtacgac gccgtcgcag
     4801 ccgttggcga cgagccaggc gcagtgctcg gcgtaccggt cgtggtcgac cgagaggtcg
     4861 tcgcggagcg ggacggcggt ggcgacgagg atgccgcgcc aggggcggtg ctgcgggtcg
     4921 gtcatgatct ctccccatca atagggtgtg acattttact gtggtgtggc ggtacgcggc
     4981 cgcgttccgc ttgcggtgcc tcagtccgtc tccggcaggg cggccaggac cccgagcggt
     5041 accggccggg cgaacggccg cccggcggtg agcgggcatc cggtcaggcc ggccaccgcg
     5101 ggcgcgcaca tccggccctg gcaccagccc atcccggccc gggtgagcag cttcaccgtg
     5161 cgcaggtcgc ctgcgcccag cgtgtcggcg gatgcccgca cctgcccggc ggtgacctcc
     5221 tcgcagcggc acaccaccgt gtcgtccggg acccggtccg cccagcccgc cggcggggcg
     5281 tacaccgcgt ccagggccgt ggcgaactcc cgcagccggg tccgggcccg ggcggcggcg
     5341 ccccagcggc gtgggtcggg caccgtgccg tgcagccggg cggcggcgga gcgtccggcg
     5401 atgtggccct cggcgagcgc gagcgccgcg ccgccgacgc cggtggcctc cccggcggcc
     5461 cagacgccgg gcacgtcggt gcgctgttcg ccgtcgacct gtacggcggt gccggacagg
     5521 gtgcagccga gggtctcggc gagatcggtg tgcggcagca tgccgtggcc cacggcgagg
     5581 gtgtcgcagg ggatgcggcg gtaggtgccg gggcggagcc gtccgtccgg ggcgagcgcg
     5641 gccaccgtca ccgcctccag ccggtcggtg ccgtgcgccg ccacgacggt gtgccgggcc
     5701 agggtgcgca ccccgtggcg cagcagccgg gccgcgtagc cggcgccctc ggcgagtttg
     5761 ccgggctccg ctgccagggc gggcgctcgg cgcagcagcg cggcgggagc ggcggactcc
     5821 accagcgcgg cgacccgggc accggccgcg gcgagcccgg tggccaccgg cagcagcagc
     5881 ggcccggtcc cggcgaccac ggccgtccgg ccgggcagca ccaggccgcc cttgagcatg
     5941 gcctgtgcgc cgcccgccgt gacgactccg ggcagcgtcc agcccgggaa gggcagcacc
     6001 tgctcgtacc cgccggtggc gagcaggacg gcgtcggcgc ggacggtgac gccctcctcc
     6061 tgcgcggggc cgcgcagggc gtgcacggtg acctcgtcgc aggcggagcc ccttcgcacg
     6121 caccacacgt gatgatccgt caggtgcgtg atgcggccgg cctcgcggtg ccggtccagc
     6181 gcgtcccgca gtcgttccca ggtgcgccac tggtggtgca gggcctgtgg ccggcgggcg
     6241 ccgagtgcgc gggcgggctg ccggtagaac tggccgccgg cctgttcggc cgcgtcgacc
     6301 aggacgacct cgacgcctcg tgcggccgcc gccagcgccc cggcgaggcc ggccgggccc
     6361 gcgccgacga cggcgagtcg cggtcgttca gccatcgtcc cggcccgtcc cctcctgcgt
     6421 gcggatcacg tctcccgggc gcaccggcac caggcaggcc cgctggttcg ggcggtcgtt
     6481 gacggtgacc aggcagtcga agcacacccc gatcccgcag aacaccccgc ggggccggcc
     6541 ggtgccgcgg gtgctgcgcc aggccgtcac gcccgccgac cacagggccg ccgcgaccgt
     6601 ctggccaggc agtgccgtca gcggccggcc gtcgaaggtg acggtgcagg cctcgcccgg
     6661 ccgggcgcgg gtcaactcca gcggattcac cggacgtcgc ctccctccgt gtcgaaccgc
     6721 tccggccgga acggtgcgag atccagttcc ggcgccttgc cggtgagcgc ctgcgcgatc
     6781 aactgcccgg tgccggtggc cagtccgatg ccggcgccct cgtgcccgca ggcgtggaac
     6841 aggccgggcg cccgcgggtc cgcgccgatc gccggcaggt ggtcgggcag gtacggccgg
     6901 aagcccgcgt acgtccgcag ggcgcggacc cgctccagga acgggaacag cccgaccgcc
     6961 ccggccgcca gcgcccgtac cgcgggcagt gacagcgagc ggtcgaaacc cactcgttcc
     7021 cgggtggcgc cgatcagcac cggaccggcg gccgtgccct ccacgaccgg cgaactgcgc
     7081 agggcggccg agtcgctggc cacgtcggcc acgtagtccg cggcgtacac cttgtgccgg
     7141 accatgcgcg gcagcggctc ggtgaccagt acgaagccgc gccgggggag caccggcagc
     7201 cggacgccgg ccagcgcagc gacctcgccg ccccaggtgc cggccgcgtt caccaccgcc
     7261 ggggcgtgga tctcgccccg gtcggtgcgg acgccgtaca ccgcgccgtc cgcggtgcgc
     7321 agcaccccgg tcacggtccg gccggtgtcc agggcggcgc cggaggcgcg gaccaggtgg
     7381 gcggcggcca gcgcgggcat gacctgggcg tcctgcgggt agtgcactcc gcccgccatg
     7441 ccgggggcca agtgcggctc cagttcggcc agtcggcggg cgtcgaccgg tacggcggtg
     7501 acgccggcgc cgcgctgggc cgccgcgaac tcccgcagcg cggccagggc ttcgggtgcc
     7561 gaggcgacca ccaggccgcc cttgggctcg tactcgaacg cggtgccgtg ctggtgggcc
     7621 agctcggccc acagccgtgc cgagagcagg gcgagttcca gttccgggcc cggttccttg
     7681 tcggagacga gcaggttgcc ctcgccggcg ccggtggtgc cgccggacac cgggccccgg
     7741 tccaccagcc ggacgtcgag tccggcccgc gcggcgtaca gcgcgcaggc cgcgcccacc
     7801 atcccggccc cgacgaccac gacatcgcag gtcagtcgct tcgtcacatc agtactatgt
     7861 cacatgtttc tctctgtggg gagtacccgg cgccgccccc gattcccagg cgtggacgcc
     7921 cccttgacgt cgtacggagc cggatcgaca ctccagggag gaaatcctag tgaacaggta
     7981 gggaatcatg gcgcgcctcc agacgggcac cggctccacg agccggacgc cgttgcgcgc
     8041 tcccctgctc acctcccgcc gtcacatcga cctgcagcgc gtctgcagcg cgatcagccg
     8101 ccaccgctga gccgggcccc acccgccccc accgaccggc cacgcccgcg ccggcgcgcc
     8161 cgtccgcacg cccaccaccc ggggagaccc atgtccatca ctccgctcgc agccgtcccg
     8221 tccgcccgcc gcgccgcccc cgtcttccgc gggcggatcg gccgggaccc ccgcagcggc
     8281 cactacgccg tgccgcaccg ctaccggctc cacctgtcca ccgcctgccc cgacgggctg
     8341 cgcctcgccg tcggccacag cctgctcggc ctggacacga gctgtccggt caccctcctg
     8401 ccccccgtcc cggaccgtcc cggcggcggc cactcggcac tgcgccccct ctacgaggcc
     8461 agcgcccacc actacaccgg cccggcgctc gcacccgtgc tgagcgacga ctggtccgga
     8521 cgcatcgtca gcacccacac ccccgacatc ctgcgcgacc tggaccggtt cggccccggc
     8581 gaccgggccc gcctgtaccc caccggactg gagtccgtga tcgaggccgt cgagcggatg
     8641 tgcgccgagg gcatcgagga ggccgcacag cgcgcaggac gggccggggc cgacccggcc
     8701 gagcgggccg ccgccctcga cacgctgctc gacaccctgg gccggctgga gcggcggctg
     8761 agcggagagg agtacctggc cgacgaccgg ctcaccgccg ccgacgtcga actgtgggtg
     8821 accctggtgc agctcgacac cgtccaccgc tgccacctcg acgcctccgc cgtgcaccgc
     8881 atcgccgacc accgcgccct gtgggcctac gcccgccgcc tggccgcccg tcccgcgttc
     8941 ggccgccacc tcgacctcga cggcatcgcc cgccgccacc acggccgctg ccagggcctg
     9001 gaggcagccg gagctgctgt ccagatcctg gactgggcag gccatgccgc ggacactcct
     9061 gacgcttctc gcaggtgaga gcgactcaac gatgtccatg tggcggacgg ccgttgacat
     9121 tcgaacggcc gactgcctta cttacggctc agaacggtca tgagcgtcag cgccaagccc
     9181 tggctcgctg accggcaacc ctcgcatcgc ggtggggtgc cccaggtgac gaccggaccg
     9241 gacggcgatt tcggtaagcg cgaggcccca cggggccgga acagtgacag gtgacgccat
     9301 gtacgcagct cccaggacgg ccacgagccg cccccagggc tgcgtaccgt cgtacgccgg
     9361 tctcctcgtc gccgaccggg ccgtcgacct gctccgcgtg aacagcgcac tgtgtaccgc
     9421 accgggctcc gcccgctgtc agggctgacg tctcctccca gcccccgcgt tcccgccgca
     9481 caccctccgc ccggtgtgcc gttgtccgcc cagcccccgg cttccgcgcg ctcccgtgtg
     9541 ccgccccgtg ccccagtgcc gtagtggttc gcatccggcc tgccgcggac ccggggtgtc
     9601 cgaatccgcc ggagcccgcc atgagtgaac ccccaggcgc cgccgtgtcc ctcgccgagg
     9661 caccacccgc cgcatccccg ccgaagtccc tgaccgccca gcgcgttcag ccgctgcgcc
     9721 ggcccggccg gtggatcgtc accgccgtcg ttctcgtgct ggtcgcgcag atcctgcacg
     9781 gactggccac gaacccgttc taccagtggg cccgcttccg ctactggttc ctgcgtccca
     9841 cgatcctcga cgggctcgtc gtcaccctcg aagtcgccgc gctcagcgcc gtgctgggcc
     9901 tgctcggtgg catcctgctg gctctcggcc ggctctccgg cagcccggta ctgcgggcgg
     9961 tgagctggac ctacacctgg ctgttccgct cggtaccgct gatcgtcgta ctgatcttcc
    10021 tctacaactt cagtgccctg tacaagacgt tgagcctcgg tatccccttc ggaccggcct
    10081 tcgtcagctt cgacgagtcg aagctcgcca ccgacatgac ggttgccgtc atcggtctcg
    10141 gcctcaacga ggccgcgtac gcggccgagg tcgtgcgcgg cggcatcctc tccgtcgacc
    10201 agggccagca cgaggcggcg gccgcgctcg gtctgcccag gggctaccag ttcacccgga
    10261 tcgtcttccc gcaggccctg aggtccatca ccccgaacta cgtcaaccag ctcatcggcc
    10321 tggtcaagag cacgtccctg gtgttctacg tctccctgct cgacctgttc ggctcggtgc
    10381 agaccatggg cagcacctac cccggcgaca tcgtgccgct gctgctcgtc gccaccgtct
    10441 ggtacctgat cctgaccagc gtcgtgtccg tcgtccagtt ctacgtcgag cggtacttcg
    10501 cccgcggtgc cacccgcagc ctgccgccga ccccgctgca gaaggcgcgg gcgggcctcg
    10561 ccgacttccg ggcccggctg cgcagggagg ccgccgtatg accgccaccg ccaccgccac
    10621 cgccaccccg gagacggccc cggccgccct ggaggtgcac gacgtccaca agtggtacgg
    10681 cacccaccgc gtcctggacg gcatcgacct gaccgtgcgc cccggggagg tcaccgcgat
    10741 cctcgggccc tccggctccg gcaagtccac cctcctgcgg gtcatcaacc acctggagaa
    10801 acccgagatc ggctacgtga gcgtcggcgg cgagctgatc ggcgtgaagc gcaacggggg
    10861 ccggctcaag gaactcagcg agcgcaccat cctcacccag cgcagccgga tcggcttcgt
    10921 cttccagaac ttcaacctct tcccgcacct gaccgtcctc gacaacgtcg ccgccgcccc
    10981 cgtcgccacg ggcaggctga acaagccgga ggcgcgggag ctggcacgcg aactgctcac
    11041 ccgggtcggt ctcggcgacc gcaccggcgc ctacccgcgg cagttgtccg gcggccagca
    11101 gcagcgcgtc gccatcgccc gcgccctcgc gctgcgtccc gggatcatcc tcttcgacga
    11161 gccgacctcg gcgttggacc ccgaactcgt cggcgaggtc ctctccgtca tcaaggacct
    11221 ggccaccagc ggtaccacgc tcgtcatcgt cacccacgag atcggcttcg cccgcgaggt
    11281 cgccgaccgg gtcgtcttca tcgacggcgg aaggatcgtc gaacagggcc cgccctccca
    11341 ggtgctggac aagccccggc acgagcggac ccgggacttc ctcagcaagg tgctctgagc
    11401 ttcagccact ccggtgaccc ggccggcccg cccagacctc cccccacgcc accctcatca
    11461 cccgtcccga acgacaagga cagccatgcg cagccacttc tcccgacgca gcctgatacg
    11521 cggcatcacc gcggcgacca cggtcgccac cctggccacc gggctcgccg cctgcggtgg
    11581 tgagagcgac gccgccacca cgaccgacgc cgccggcacg gtgaccgtgg gccgggtgtc
    11641 caacggcgcg gccaagcaga ccgagctgaa ggtctccgag gtgaagtccc tcaacgccga
    11701 actgcccgcc gcgatccgca agagcggcac cctgaggatc ggtgtcggcg ccctgcccga
    11761 cggcttcccg ccgctggcct acatcggcgg cgaccagaag accctcaccg gtgccgagcc
    11821 ggacctgggc cgcctggtcg ccgcggtcct cggactgaag ccgcagttct ccaacgccac
    11881 ctgggagaac atgttcgtcg gtatcgacag cggcaagtac gacgccgcct tcgccaacat
    11941 caccgacacc gaggaacgca agaagaagta cgacttcgcg tcctaccgca aggacaacgt
    12001 cggcttcgag gtgctgaaga agagcacctg gaacttcgac gggaactacg agaacctcgc
    12061 cggcaggacc gtcgccgtgg acaacggcac gaaccaggag aagatcctcc tggagtggca
    12121 gacgaagctg aagaaggagg gcaagaccct caccgtcaag cactaccaga gcaagaacgc
    12181 cacctacctg gcgctgaccg gcggcaggat cgacgcctac ttcgccgcca accccggtgt
    12241 cgcgtaccac atcacgcaga ccgcgaagtc accgaacccc acccgcagcg cgggcacctt
    12301 ctccggcgcg ggcgccacgc tgcagggcct gatcgccgcg accacgaaga aggacagcgg
    12361 actcgccaag ccgttcgcgg acgccgtcaa ctacctgatc gagcacggtc agtacgccaa
    12421 gtggctggcc gcctacaacc tctccgacga gtccgtggcg aagtcggagg tcaacccgcc
    12481 cggactgccg ctcaccaact cctgaccacc cgtcaccccg cccagagaca gccacctaga
    12541 gaggactccg ctcccgtgac ccacccgacc ggcgtcggta cgagcccccg ggctcagcct
    12601 gcgccgccgc tgcccgcatc gagcagctgc gcggcccggg aacaaccggc gccggccggg
    12661 cgttggacgt catgacgaga tccaccgagc ggacgccgat ccggcccgcc gcggccgacg
    12721 gagggaggtg acggccgtga cccgagtgcc ctcgcaggcg cgcccgccgc acgccccgca
    12781 cccgtaccgc tccgtccgtc tgcactcccg gccgcacata gacctccagc gcgtgtccgc
    12841 cgcgctc
//
