LOCUS       NZ_CP071839            26824 bp    DNA     linear   CON 20-APR-2024
DEFINITION  Streptomyces cyanogenus strain S136 chromosome, complete genome.
ACCESSION   NZ_CP071839
VERSION     NZ_CP071839.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces cyanogenus
  ORGANISM  Streptomyces cyanogenus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8773899)
  AUTHORS   Hrab,P., Ruckert,C., Busche,T., Ostash,I., Kalinowski,J.,
            Fedorenko,V., Yushchuk,O. and Ostash,B.
  TITLE     Complete genome sequence of Streptomyces cyanogenus S136, producer
            of anticancer angucycline landomycin A
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8773899)
  AUTHORS   Hrab,P., Ruckert,C., Busche,T., Ostash,I., Yushchuk,O.,
            Kalinowski,J. and Ostash,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2021) Genetics and Biotechnology, Ivan Franko
            National University of Lviv, 4 Hrushevskoho St, Lviv, Lviv region
            79005, Ukraine
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method :: Newbler v. 2.8; Canu v. 1.8; Unicycler v. 0.14
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 974878.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017526105.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 09:57:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,747
            CDSs (total)                      :: 7,656
            Genes (coding)                    :: 7,375
            CDSs (with protein)               :: 7,375
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 281
            CDSs (without protein)            :: 281
            Pseudo Genes (ambiguous residues) :: 0 of 281
            Pseudo Genes (frameshifted)       :: 129 of 281
            Pseudo Genes (incomplete)         :: 239 of 281
            Pseudo Genes (internal stop)      :: 25 of 281
            Pseudo Genes (multiple problems)  :: 104 of 281
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:56:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7417158
            Orig. end                         :: 7443982
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071839.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Bohdan Ostash, 4
            Hrushevskoho St., Lviv, 79005, Ukraine.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26824
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26824
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26824
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16824](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16824
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(283..1224)
                     /locus_tag="S1361_RS33250"
                     /old_locus_tag="S1361_33225"
     CDS             complement(283..1224)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="S1361_RS33250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33225"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_208035573.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHSHVPAPGTATAAYRGRLRVALGITLTVMVVEIAG
                     GLIADSLALIADAAHMATDAVGLGMALVAVHFANRPPSTNRTFGYARAEILAALANCLL
                     LLVVGGYVLYEAVQRFVEPAATRGGLMVVFGLVGLVANSVSLVLLMRGQKESLNVRGAF
                     LEVAADALGSVAVLISAAVILTTGWQPADPVASLVIGLMIVPRTLKLLRETLDVLLEAA
                     PKGVDMAEVRAHILALDGVEDVHDLHAWTITSGMPVLSAHVVVGSEALNAIGHEKMLHE
                     LQGCLGDHFDVEHCTFQLEPGGHAEHEARLCH"
     misc_feature    1296..1310
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1358..2329)
                     /gene="galE"
                     /locus_tag="S1361_RS33255"
                     /old_locus_tag="S1361_33230"
     CDS             complement(1358..2329)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-206). E-value:
                     1.9e-11. Score: 35.5. Matches aSDomain:
                     nrpspksdomains_S1361_RS33255_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431370.1"
                     /locus_tag="S1361_RS33255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33230"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_208035574.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.5e-18, bitscore:
                     63.1, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.9e-10,
                     bitscore: 38.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMAGAGESVVALDDLSAAVPARLPAEV
                     PLVQGSTLDGALLKRVFAEYGVTGVVHLAARKQVAESVAQPTRYYRENVGGLATLLDAI
                     AEAGVGRLLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGIST
                     VCLRYFNVAGAAAPELADTGVFNIVPMVFDRLTRGEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLADAHLAAARRLAGGEATGDLTLNIGRGEGVSVRELISVVGEVTGDRREPVVEGRRP
                     GDAPRAVASAERAAEVLGWRARRGVREMVESAWAGWRLHHGR"
     aSDomain        complement(1712..2131)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_S1361_RS33255_NAD_binding_4.1"
                     /evalue="1.90E-11"
                     /label="S1361_RS33255_NAD_binding_4.1"
                     /locus_tag="S1361_RS33255"
                     /protein_end="206"
                     /protein_start="66"
                     /score="35.5"
                     /tool="antismash"
                     /translation="VTGVVHLAARKQVAESVAQPTRYYRENVGGLATLLDAIAEAGVGR
                     LLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGISTVCLRYFN
                     VAGAAAPELADTGVFNIVPMVFDRLTRGEAPRIFGD"
     CDS_motif       complement(2258..2326)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_S1361_RS33255_0001"
                     /evalue="6.40E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="S1361_RS33255"
                     /protein_end="24"
                     /protein_start="1"
                     /score="18.8"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMAGAG"
     gene            2597..4402
                     /locus_tag="S1361_RS33260"
                     /old_locus_tag="S1361_33235"
     CDS             2597..4402
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="S1361_RS33260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33235"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_208035575.1"
                     /transl_table=11
                     /translation="MSTAIVTGQPVPGSSLEHDLRSLGFEVRVAADAAETESLLAAVPA
                     DRRVALVDSRFVGHPHALRLGLTDPRFPLAAVPGAVTAQPAARPALTRAVARETSADGG
                     TGAGSGPALAVDSLADRVATALDADGGTVHRPELGSLVATVPADPQARNEARQAVAAVD
                     DEAVRLKSAVKSRDGFFTTFFISPYSRYLARWCARRGLTPNQVTTASLLTALIAAGCAA
                     TGTRGGFVAAGVLLIASFVLDCTDGQLARYALKYSTLGAWLDATFDRAKEYAYYAGLAL
                     GAARGGDDVWALALGAMVLQTCRHVVDFSFNEANHDATANTSPTAALSDKLDSVGWTVW
                     LRRMIVLPIGERWALIAVLTAATTPRITFYVLLVGCAFAATYTTAGRVLRSVTRKAQRT
                     DRAARALADLADNGPLASFVARTTRGRLGSPLLVALAGTAVLAVSLFSGVTWAPVAGAL
                     VYATAAGRALYRPLKGALDWLVPPLFRFAEYGTVLVLAAEADVNGALPAAFGLVAAVAY
                     HHYDTVYRIRGNAGAPPAWLVRAIGGQEGRTLLVTALAALLTAAQFKAALTVLAVAVAL
                     VVLVESIRFWVSAGAPAVHDEGETA"
     gene            4399..5151
                     /locus_tag="S1361_RS33265"
                     /old_locus_tag="S1361_33240"
     CDS             4399..5151
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="S1361_RS33265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33240"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_208035576.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.8e-09, bitscore:
                     36.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDSLPKALVPVGPAGIEDSITVLDLTLG
                     NFAEIGLTEVAIIVGYRKEAVYERKAALEAKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVEKTLLAARGEGKKIILALDTVKNLADEEMKVVVDPDKGMTR
                     ITKLMDPAEATGEYIGVTLIEGDAAPELADALKTVWETDPQQFYEHGYQELVNRGFRID
                     VAPIGDVKWVEIDNHDDLARGREIACQY"
     gene            5139..6200
                     /locus_tag="S1361_RS33270"
                     /old_locus_tag="S1361_33245"
     CDS             5139..6200
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="S1361_RS33270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33245"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_208035577.1"
                     /sec_met_domain="Fe-ADH (E-value: 3.4e-22, bitscore: 77.5,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 2.3e-06, bitscore:
                     25.8, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRPGALDDLGSVLADERISQSGRLAIAVSG
                     GSGARLRERIAPSLPGASWYEVGGGTIDDAVRLASDIKAGHYDAVVGLGGGKIIDCAKF
                     AAARVGLPLVAVATNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVIIDLDVIREAPVRF
                     VRSGIGDAISNISAVADWELASRVNGEKIDGLAAAMARQAGEAVLRHPGGVGDDGFLQV
                     LAEALVLTGIAMSVSGDSRPSSGACHEINHAFDLLYPKRAAAHGEQCGLGAAFAMYLRG
                     AHEESAYMAEVLRRHGLPVLPEEIGFTVDEFVRAVEFAPETRPGRYTIIEHLDLKTNQI
                     KDIYADYVKAIGS"
     gene            6178..6957
                     /locus_tag="S1361_RS33275"
                     /old_locus_tag="S1361_33250"
     CDS             6178..6957
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="S1361_RS33275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33250"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_208035578.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREVSLRVDRYLV
                     NTRVTPNQLTYLMTVCGVLAAPALLVPGIAGAVLGVVATQLYLLLDCVDGEIARWKKQY
                     SLGGVYLDRVGAYLTDAAVLVGLGLRAADLWGTGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQTGRPPVQEAASELRSSGMALARRAASALKFHRLILGIEASLLILVLAIVDQ
                     ARGDLFFTRLGTAVLAGIAMLQTLLHLVSILASSRLK"
     gene            6966..7838
                     /locus_tag="S1361_RS33280"
                     /old_locus_tag="S1361_33255"
     CDS             6966..7838
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="S1361_RS33280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33255"
                     /product="glycosyltransferase"
                     /protein_id="WP_208036878.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.8e-13,
                     bitscore: 47.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVIITMGNRPEELRALLDSVAKQDGDPVEVVVVGNGSPVPD
                     VPEGVRTVELPENLGIPGGRNVGIEAFGPGGRNVDILLFLDDDGLLARHDTAELCREAF
                     AADPELGIISFRIADPDTGETQRRHVPRLRASDPMRSSRVTTFLGGANAVRTRVFAEVG
                     GLPDEFFYAHEETDLAWRALDAGWMIDYRSDMVLYHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPALLVPVYLGVWLLLTLLRRPSGPALKAWFGGFREGWTTPCGPRRPMRWRTVWRL
                     TRLGRPPVI"
     gene            7918..8847
                     /locus_tag="S1361_RS33285"
                     /old_locus_tag="S1361_33260"
     CDS             7918..8847
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="S1361_RS33285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33260"
                     /product="ABC transporter permease"
                     /protein_id="WP_208035579.1"
                     /transl_table=11
                     /translation="MSETTHDGTVTVTAAPSPDEGLTAAELAEKYGLSVSGARPSLVEY
                     VRQLWGRRHFVLAFSQAKLTAQYSQAKLGQLWQVATPLLNAAVYFFIFGLILHASRGMS
                     RDVYIPFLVTGVFVFTFTQSSVMSGVRAISGNLGLVRALHFPRAALPVSFSLQQLQQLL
                     FSMIVLFVVAIGFGSYPSPSWLLIVPVLVLQFLFNTGLALIVARMGAKTPDLAQLMPFV
                     LRTWMYASGVMFSIPVMLQDKPQWIATVLQWNPAAIYMDLMRFALIDGYGAENLPAHVW
                     AAAGGWAVLFAVGGFVYFWKAEERYGRG"
     gene            8840..9640
                     /locus_tag="S1361_RS33290"
                     /old_locus_tag="S1361_33265"
     CDS             8840..9640
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330378.1"
                     /locus_tag="S1361_RS33290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33265"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_208035580.1"
                     /transl_table=11
                     /translation="MAEQNAGQDAQERRPTVIADDLHIVYRVNGAKTGKGSATAALSRI
                     LRRGSDDAARGVRKVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAEKGKV
                     YTDGQPSLLGVNAALMNDLTGERNIILGGLAMGMSREQIKERYQDIVDFSGINEKGDFI
                     TLPMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQKRSEERIRELRKEAGTV
                     FLVSHNNKSIRDTCNRVLWLERGELRMDGPTDEVLKEYEKFTGK"
     gene            10001..10897
                     /gene="hpnC"
                     /locus_tag="S1361_RS33295"
                     /old_locus_tag="S1361_33270"
     CDS             10001..10897
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042802.1"
                     /locus_tag="S1361_RS33295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33270"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_208035581.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.2e-41, bitscore:
                     140.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.5e-40,
                     bitscore: 136.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATGTAPDLERATLDKAAGENFPVAPFFLPRAWREDLMAVYGFA
                     RLVDDIGDGDLAPGGADARLLGLSPAAAADRPALLDAFETDLRRVFGGTPRHPLLRRLQ
                     HTVRRRALTPEPFLGLVAANRQDQLVTRYETYDDLLAYCELSANPVGRLVLAVTGTSTP
                     ERIRLSDAICTALQIVEHLQDVAEDLGRDRIYLPAEDMKRFHVQEADLAAKTASASVRA
                     LVAYEAQRARDLLDEGAPLVGSVHGRLKLLLAGFVAGGRAAIRAIAAAEYDVLPGPPRP
                     GKVRLLREAGAILRGEG"
     gene            10894..11856
                     /gene="hpnD"
                     /locus_tag="S1361_RS33300"
                     /old_locus_tag="S1361_33275"
     CDS             10894..11856
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="S1361_RS33300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33275"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_208035582.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.9e-55, bitscore:
                     186.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.3e-68,
                     bitscore: 230.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVESPPHVSAPVLAAYSYCEAVTGQQARNFAYGIRLLPTAKR
                     RAMSALYAFSRRVDDIGDGDLAGEVKLARLEDTRALLARIREGEVEEDDTDPVAVALSH
                     AADAFPIPLGGLDELIDGVQMDVRGETYETWDDLKVYCRCVAGAIGRLSLGVFGTEPGA
                     RGAERAAEYADTLGLALQLTNILRDVREDAAGGRTYLPADDLAKFGCSAGFDGPTPPEG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGHEKAYVAVRGLSGLDTRHVTRHVSRRSVRRRA"
     gene            12122..13549
                     /gene="hpnE"
                     /locus_tag="S1361_RS33305"
                     /old_locus_tag="S1361_33285"
     CDS             12122..13549
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546810.1"
                     /locus_tag="S1361_RS33305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33285"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_208035583.1"
                     /sec_met_domain="DAO (E-value: 1.2e-06, bitscore: 27.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDGSSPAPARAGTPRTAGRSAVVVGGGLAGITAALALADAGVRV
                     TLLEGRPRLGGLAFSFQRGELTVDNGQHVYLRCCTAYRWFLDRIEGAALAPLQDHLDVP
                     VVDVAKPEGRRLGRLRRDPLPVPLHLGRSLAAYPHLSLAERAAVGRAALALKGLDLADP
                     ALDTQDFGSWLAAHGQSARAVEALWDLVGVATLNAVAGDASLGLAAMVFKTGLLSDPGA
                     ADIGWARVPLGELHDRLARKALDSAGVRTEVRTRVTSVSFNENGTWSVQVPGENLDTDA
                     VVLAVPQREAHDLLPPGALDAPERLLEIGTAPILNIHVLYDRKVLARPFFAALGTPVQW
                     VFDRTDASGLGSGQYLALSQSAAQDEIDTPVAELRERYLPELERLIPGTRAAAVLDFFV
                     TRERTATFAPAPGVGRLRPGARTKAPGLYLAGAWTATGWPATMESAVRSGVSAADAALS
                     ALGRPRPRHLFEFEEAA"
     gene            13549..14682
                     /locus_tag="S1361_RS33310"
                     /old_locus_tag="S1361_33290"
     CDS             13549..14682
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058832.1"
                     /locus_tag="S1361_RS33310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33290"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_208035584.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.2e-57, bitscore:
                     192.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQQAARPRTPGTATRGETVPTVPPASTPAPRAAVDVTALLERG
                     RTLATPVLRAAVDRLAPPMDTVAAYHFGWIDAAGNPADGDGGKAVRPALAVLSAEVTGA
                     APEVGVPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAG
                     EVLLELGTVEAGRATRRLTTATRALIDGQAQDISYEHRDRVSVEECLEMEGNKTGALLA
                     CASSIGAVLGGADDATADALERYGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRK
                     KSLPVVAALAAGGPASEQLGEILAADAKSSDFQNFSEEEFAARAALIEEAGGREWTAGE
                     ARRQHTVAIEALDAVDMPDRVRDSFTALADFVVVRKR"
     gene            14800..16824
                     /gene="shc"
                     /locus_tag="S1361_RS33315"
                     /old_locus_tag="S1361_33295"
     CDS             14800..16824
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676206.1"
                     /locus_tag="S1361_RS33315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33295"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_208035585.1"
                     /sec_met_domain="T2TS (E-value: 1.7e-152, bitscore: 507.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGATLPSRAAAASDTTLITPETAGVQEAAARAARRAT
                     DYLLARQDAQGWWKGDLETNVTMDAEDLLLRQFLGILEEDTAQAAAKFIRGEQREDGTW
                     ATFYGGPGELSTTVEAYVALRLAGDAPDDPHMAKASAWIRERGGIAAARVFTRIWLALF
                     GWWKWEDLPELPPELIYFPTWFPLNIYNFGCWARQTIVPLTIVSAKRPVRPAPFALDEL
                     HTDPANPNPPQPLAPVASWDGLFQRLDKVVRGYRRFAVRRLRRAAMNSAARWIIERQEN
                     DGCWGGIQPPAVYSVIALHLLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVW
                     DTCLATIALVDAGLPVDHPQLVKAADWMLGEEIVRPGDWAVRRPHLPPGGWAFEFHNDN
                     YPDIDDTAEVALALRRVRHHDPERVDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPN
                     RLPFCDFGEVIDPPSADVTAHVVEMLAAEGLAQDPRTRRGIDWLLAEQEPDGSWFGRWG
                     VNYVYGTGSVVPALTAAGLPGTHPAIRRAVAWLESVQNDDGGWGEDLRSYKYAKEWSGR
                     GASTASQTAWALMALLAAGERESKAVERGVQWLAGTQREDGTWDEPYFTGTGFPWDFSI
                     NYHLYRQVFPLTALGRYLHGDPFERDLLTRKPLSGAKVS"
     gene            16826..17467
                     /locus_tag="S1361_RS33320"
                     /old_locus_tag="S1361_33300"
     CDS             16826..17467
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431357.1"
                     /locus_tag="S1361_RS33320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33300"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_208035586.1"
                     /transl_table=11
                     /translation="MNNQPAPAPLLIACALGIEHLALRTGDHSGAGGPVTFVRTGMGPR
                     AAERSVTRHLAGQAAADTAVLATGFCAGLAPGMHPGDLVVAEETRDPRGTVPCVGTELL
                     VKELVRLLPGRTVHTGPLTGSDHVVRGPERSDLLATGAIAVDMESAATLLAAVRTGERP
                     VAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSILPAFFEWHRSLLLPRR"
     gene            17473..18495
                     /gene="hpnH"
                     /locus_tag="S1361_RS33325"
                     /old_locus_tag="S1361_33305"
     CDS             17473..18495
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="S1361_RS33325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33305"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_208035587.1"
                     /sec_met_domain="PF04055 (E-value: 3.7e-17, bitscore: 62.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.2e-08, bitscore: 33.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLAEQKLRRRDKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKRKYVF
                     LCTNAMLLRKKMDQFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNFLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFAGGNRRKWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEKTDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNRE
                     "
     gene            18500..19633
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="S1361_RS33330"
                     /old_locus_tag="S1361_33310"
     CDS             18500..19633
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="S1361_RS33330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33310"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_208035588.1"
                     /transl_table=11
                     /translation="MTAVPLGVPEVPGRPVAPRRLSRQVQVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALATIARKSQIPVIADIHFQPKYV
                     FAAIEAGCAAVRVNPGNIKKFDDQVEEIARAARDHGTPVRIGVNAGSLDRRLLQKYGKA
                     TPEALVESALWEASLFEEHDFHDIKISVKHNDPVVMIEAYRQLAEQCDYPLHLGVTEAG
                     PAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPAEEVKVGIQILEALGLRQRRLEIVSC
                     PSCGRAQVDVYKLAEEVTAGLDGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQI
                     FVKGEVVKTVPESKIVETLIEEAMKLAERTSPADQVS"
     gene            19665..21563
                     /gene="dxs"
                     /locus_tag="S1361_RS33335"
                     /old_locus_tag="S1361_33315"
     CDS             19665..21563
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676210.1"
                     /locus_tag="S1361_RS33335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33315"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_208035589.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 3.5e-111,
                     bitscore: 369.6, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.3e-06, bitscore:
                     25.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILENIRGPRDLKALSEAELGELSEEIREFLVHAVSRTGGHLGP
                     NLGVVELSIALHRVFESPVDRILWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDVIENSHASTALGWADGLAKAHQVLGEKGHVVAVIGDGALTGGMAWEALNNIAAAR
                     DRPLIIVVNDNERSYAPTIGGLANHLATLRTTDGYEKVLAWGKEVLQRTPVVGTTLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYLGPIDGHDIQAVESALRRAKRFHGPVLVHCLTEK
                     GRGYEPALAHEEDHFHTVGVMDPLTCEPLAPSNGPSWTSVFGEEMVRIGEEREDVVAIT
                     AAMLHPVGLAGFAERFPDRVWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGTDGPSHNGMWDMSVLQVVPGLRIAAPRDAGQLRAQL
                     REAVAVDDAPTLVRFPKESVGPSVPALDRLGGMDVLHRAGRPEVLLVAVGVMASVCLQA
                     AELLEARGIGCTVVDPRWVKPVDPALPGLAAEHRLVAVVEDNSRSAGVGSAVALALGDA
                     DVDVPVRRFGIPEQFLAHAKRSEVLADIGLTPVEIAGRISGSLAVGDVGGTVKESE"
     gene            21560..22945
                     /locus_tag="S1361_RS33340"
                     /old_locus_tag="S1361_33320"
     CDS             21560..22945
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 1.5e-86.
                     Score: 282.4. Matches aSDomain:
                     nrpspksdomains_S1361_RS33340_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494124.1"
                     /locus_tag="S1361_RS33340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33320"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_208035590.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.5e-84, bitscore:
                     282.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSEFDLGALLAERGAERYELHAKHLNPQLPRMLHTIGFDKVYER
                     AEGAHFFDAEGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDLDLADLTRFDCQPLPGL
                     LAERLLTHSPHLDRVFFGNSGTEAVETALKFARYATGRPRVLYCDHAFHGLTTGSLSVN
                     GERGFRDGFAPLLPDTAVPLGDLDALARELKKGDVAALIVEPIQGKGVHEAPPGYLRAA
                     QELLHRHKALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVCVAKALSGGYVPVGATLGK
                     EWIFKKVYSSMDRVLVHSASFGSNAQAMACGLAVLSVMENEQIVAGVRRTGELLKSRLT
                     ALIDTYELLADVRGRGLMIGIEFGKPSSLKLRSRWTMLQAARKGLFAQMVVVPLLQKHR
                     ILTQVSGDHLEVIKLIPPLVVDETDVERFVEAFTAVMDDAHSGGGLMWDFGKTLIKQAV
                     ANR"
     aSDomain        21683..22648
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_S1361_RS33340_Aminotran_3.1"
                     /evalue="1.50E-86"
                     /label="S1361_RS33340_Aminotran_3.1"
                     /locus_tag="S1361_RS33340"
                     /protein_end="363"
                     /protein_start="41"
                     /score="282.4"
                     /tool="antismash"
                     /translation="VYERAEGAHFFDAEGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DLDLADLTRFDCQPLPGLLAERLLTHSPHLDRVFFGNSGTEAVETALKFARYATGRPRV
                     LYCDHAFHGLTTGSLSVNGERGFRDGFAPLLPDTAVPLGDLDALARELKKGDVAALIVE
                     PIQGKGVHEAPPGYLRAAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKEWIFKKVYSSMDRVLVHSASFGSNAQAMACGLAVLSVMENE
                     QIVAGVRRTGELLKSRLTALIDTYELLADVRGRGLMIGIEF"
     misc_feature    23022..23033
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     gene            23026..23655
                     /locus_tag="S1361_RS33345"
                     /old_locus_tag="S1361_33325"
     CDS             23026..23655
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676212.1"
                     /locus_tag="S1361_RS33345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33325"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_208035591.1"
                     /transl_table=11
                     /translation="MNASDAAPAPGPAPDDGLSAVAPQLRSLRRRAGLTLEAAARAAGL
                     SPAHLSRLETGHRQPSLPMLLALARIYGTTVSELLGETVADRDAIVRAADMEPTRAGGW
                     TYVQAGAPGRGMQALRVRVPYGSQGDIVRVHPGEEWLYVLTGRLRLRLGDTAHLLGPGD
                     SAHFDSLTPHRLAAEDHDGVELLFVHTLLQSPTATLCLGAPTGELP"
     gene            23652..23774
                     /locus_tag="S1361_RS33350"
                     /old_locus_tag="S1361_33330"
     CDS             23652..23774
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676213.1"
                     /locus_tag="S1361_RS33350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33330"
                     /product="DUF6126 family protein"
                     /protein_id="WP_208035592.1"
                     /transl_table=11
                     /translation="MSDFEEKFPRSLWIRLIIYIALGHVLAAFLYLLFAVGGKG"
     gene            complement(23789..24586)
                     /locus_tag="S1361_RS33355"
                     /old_locus_tag="S1361_33335"
     CDS             complement(23789..24586)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="S1361_RS33355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_33335"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_208035593.1"
                     /transl_table=11
                     /translation="MTQQVPSTEPELAGVRNFRDVGGLPTVDGRRVRHGVLFRSGHLAH
                     ATQEDAAFLASLGLHTVFDFRNAADQKLEGPDVELPGVRYVNLPLSDPADGAAFWKMVR
                     EGDLDQLRAILDDGKGAARMIASYRKIVTERTAEHSRVLHALADDSVPALMHCAAGKDR
                     AGISVAVTLLAVGVERDAILADYLESAAGHRRYKVRRSGSADTAYTPEVMELLDPLFDA
                     RAEYLEAAFTSIEQTWGDVDTYLARGLGFSAESRDRLRERLLH"
     misc_feature    26278..26293
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.01"
                     /tool="antismash"
     misc_feature    26336..26349
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
ORIGIN
        1 tccgccgtac cgatcgtcac gcccttctcg tcgaccagtt ccagcaaaat cgcctctgcg
       61 gtgccgttcg acgagctgtg cgtcgcggtg gcaggtgtga tcggcatacc catccttcgc
      121 ctcggtcttc gcaccccaag tctgccgtac gaatccggca ctcccggcac gtccacgggt
      181 ccgcgcgcgg cgcggcaccg ggagtcggac ccggtggatc atcgtgcccg gcggccggcg
      241 ccgggaaccg tcctggggtg cgccgaacgg gagtgcgtac ggtcagtggc acagccgcgc
      301 ttcgtgctcc gcgtggccgc ccggctccag ctggaaggtg cagtgctcca cgtcgaagtg
      361 gtcgcccagg cagccctgca actcgtgcag catcttctcg tgcccgatgg cgttcagcgc
      421 ctcggagccg accaccacgt gcgccgacag caccggcatg cccgaggtga tcgtccaggc
      481 gtgcaggtcg tggacgtcct ccacaccgtc cagcgccagg atgtgcgcac ggacctccgc
      541 catgtcgacg cccttcgggg ccgcctccag cagtacgtcg agcgtctcgc gcagcagctt
      601 cagcgtccgg ggcacgatca tcagcccgat gaccagcgag gcgaccgggt ccgccggctg
      661 ccagccggtg gtcaggatca cggccgccga gatcagcacc gccaccgagc ccagcgcgtc
      721 cgcggccacc tccaggaagg cgccgcgcac gttcaggctc tccttctggc cgcgcatcag
      781 caggaccagc gagacggagt tcgcgaccag gccgacgagg ccgaacacga ccatcaggcc
      841 gccccgggtc gccgcgggct ccacgaaccg ctggaccgcc tcgtacagga cgtatccgcc
      901 gaccacgagc agcagcaggc agttggccag ggccgcgagg atctccgcgc gggcgtagcc
      961 gaaggtgcgg ttggtgctcg gcgggcggtt cgcgaagtgc acggcgacca gcgccatgcc
     1021 gaggcccacc gcgtcggtcg ccatgtgggc cgcgtccgcg atcagcgcga gcgagtccgc
     1081 gatcaggccg ccggcgatct cgaccaccat gaccgtcagg gtgatgccga gcgcgacccg
     1141 cagccggccc cggtacgcgg ccgtggccgt gcccggggcc ggcacgtggg agtgcgcgtg
     1201 cccgtggtcg tgcccagccc ccatgactac cgccttccgt gtgcctgccc ggaggccagt
     1261 gaactacggg gccgggccat ggggcaacgc ggcactgaac accgttgtca tgtgccgtga
     1321 cctgcggaaa tgttccgcag gtcagcgcgg cccgggctca ccggccgtgg tgcagacgcc
     1381 agcccgccca cgccgactcg accatctccc gcaccccgcg ccgggcccgc cagcccagca
     1441 cctcggcggc ccgttcggcc gaggccaccg cacgcggtgc gtcgccggga cggcggccct
     1501 ccaccacggg ctcccggcgg tccccggtga cctccccgac gaccgagatc agctcgcgca
     1561 ccgagacgcc ctcgccccgg ccgatgttca gcgtcagatc gccggtcgcc tccccgccgg
     1621 ccagccgccg ggccgccgcg aggtgggcgt ccgcgaggtc ggcgacgtgg atgtagtccc
     1681 ggacacaggt gccgtccggc gtcgggtagt cgtcaccgaa gatgcgcggg gcctcgcccc
     1741 gggtgaggcg gtcgaagacc atcggcacga tgttgaacac gcccgtgtcc gcgagctccg
     1801 gcgccgccgc gcccgccacg ttgaaataac gcaggcagac cgtggagatc ccgtgcgccc
     1861 ggcccgccgc ccggaccagc cactcgccgg ccagcttggt ctcgccgtac gggttcaccg
     1921 gcgcgcacgg ggtgtcctcg gtgatcaggt ccacgtccgg gttgccgtac acggccgccg
     1981 acgaggagaa cagcagccgg ccgacgcccg cctcggcgat cgcgtccagc agggtggcca
     2041 ggccgcccac gttctcccgg tagtagcggg tgggctgcgc caccgactcc gcgacctgct
     2101 tgcgggccgc gagatggacg acgcccgtca cgccgtactc cgcgaagacc cgcttcagca
     2161 gcgccccgtc cagtgtcgag ccctggacca gcggcacctc ggccgggagc cgcgcgggaa
     2221 cggcggccga caggtcgtcc agcgccacca cgctctcccc ggcgcccgcc atggcccgtg
     2281 ccacatgcgc cccgatgtat ccggctccgc cggtgatcag ccacgtcatg gtcgtccacc
     2341 ctatgccgag ccgcccggtg tcccggttgc ccgggtctgc cccatcggtt tgtgggccgg
     2401 gcccccgatc cccgatgatg atcgcggcaa aggccggggc agcccccccg tgggccgggc
     2461 cgtgaacggc cggtgaacgc ggcctccggc cgatccgata gcctctgccg acatgccgcc
     2521 cgggtgccgc aggcaagggc gccccaccac gcagaccacc ggcgcccgag cgccggcacc
     2581 cagggagtga gttcggttgt cgaccgccat cgtcaccggt cagccggtcc ccggatcgtc
     2641 actggagcac gatctgcggt ccctcggctt cgaggtgcgg gtggcggccg acgccgccga
     2701 gacggagtcc ctgctcgccg ccgtgccggc cgaccggcgc gtggccctgg tcgactcccg
     2761 cttcgtcggc cacccgcacg cgctgcgcct cggcctgacc gacccgcgct tcccgctcgc
     2821 cgccgtgccc ggcgccgtca cggcccagcc cgccgcccgg cccgcgctca cccgggccgt
     2881 ggcccgtgag acctccgccg acggcggcac cggggcaggc agcggtccgg cgctcgccgt
     2941 ggacagcctc gccgaccggg tcgccaccgc gctcgacgcc gacggcggca cggtgcaccg
     3001 gcccgagctg ggcagcctgg tcgccacggt gccggccgac ccgcaggccc gcaacgaggc
     3061 ccggcaggcc gtggccgccg tcgacgacga ggcggtacgc ctgaagtcgg ccgtgaagtc
     3121 ccgcgacggc ttcttcacca ctttcttcat cagcccgtac tcgcgctacc tcgcgcgctg
     3181 gtgcgcccgc cgcggactga ccccgaacca ggtcaccacg gcctcgctgc tcaccgcgct
     3241 gatagccgcg ggctgtgcgg cgaccggcac ccgtggcggt ttcgtcgcgg ccggtgtgct
     3301 gctgatcgcc tccttcgtcc tggactgcac cgacggccag ctggcccgct acgcgctgaa
     3361 gtactccacc ctcggcgcct ggctcgacgc caccttcgac cgggccaagg agtacgccta
     3421 ctacgccggc ctcgccctcg gcgcggcccg cggcggcgac gacgtgtggg ccctcgccct
     3481 cggcgcgatg gtcctgcaga cctgccggca cgtggtggac ttctccttca acgaggccaa
     3541 ccacgacgcc accgccaaca ccagccccac cgccgcactc tccgacaagc tcgacagcgt
     3601 cggctggacg gtctggctgc gccgcatgat cgtgctgccg atcggcgagc gctgggcgct
     3661 gatcgcggtc ctcaccgcgg ccaccacccc gcggatcacc ttctacgtcc tgctcgtcgg
     3721 ctgcgccttc gccgcgacgt acaccacggc gggccgggtg ctgcgctcgg tgacgcggaa
     3781 ggcgcagcgc acggaccggg cggcgcgggc actggcggac ctcgccgaca acggcccgct
     3841 cgcctcgttc gtggcccgga ccacccgggg ccgcctcggt tccccgctgc tggtggccct
     3901 ggccggcacg gccgtcctcg cggtgtccct cttctccggt gtgacctggg cacccgtcgc
     3961 cggtgccctg gtgtacgcga ccgccgccgg ccgggccctg taccgccccc tcaagggcgc
     4021 ccttgactgg ctcgtcccgc cgctgttccg gttcgccgaa tacggcaccg tcctggtact
     4081 ggcggccgaa gcggacgtga acggggccct tcctgcggct ttcggcctgg tggcggccgt
     4141 cgcctaccat cactacgaca cggtgtaccg catccgcggc aacgccggag cgccgccggc
     4201 ctggctggtg cgcgccatcg ggggtcagga ggggcggacg ctgctcgtca ccgccctggc
     4261 cgcattgctc accgctgcgc agttcaaggc cgcgctcacg gtcctcgccg tggccgtcgc
     4321 cctggtggtg ctcgtcgaga gcatccgctt ctgggtgtcc gctggggcgc ccgccgtaca
     4381 cgacgaagga gaaaccgcat gatcggcctc gtgctcgcgg ccggcgccgg acggcgtctg
     4441 cgcccctaca ccgacagcct gccgaaggcg ctggtgccgg tggggcccgc gggcatagag
     4501 gactcgatca cggtgctgga cctgacgctc ggcaacttcg ccgagatcgg gctgaccgag
     4561 gtcgcgatca tcgtcggcta ccgcaaggag gccgtctacg agcgcaaggc ggccctggag
     4621 gccaagtacg gcctcaagct caccctcatc gacaacgaca aggccgagga gtggaacaac
     4681 gcctactccc tgtggtgcgg ccgtgacgcc ctcaaggacg gcgtgatcct cgccaacggc
     4741 gacaccgtgc acccggtctc cgtcgagaag acgctgctcg cggcccgcgg cgagggcaag
     4801 aagatcatcc tcgccctgga cacggtgaag aacctggccg acgaggagat gaaggtcgtc
     4861 gtcgaccccg acaagggcat gacgaggatc accaagctga tggacccggc cgaggccacc
     4921 ggcgagtaca tcggcgtcac cctgatcgag ggcgacgccg cgccggagct ggccgacgcg
     4981 ctgaagacgg tctgggagac cgacccgcag cagttctacg agcacggcta ccaggaactc
     5041 gtcaaccggg gcttccgcat cgacgtggcg ccgatcggcg acgtcaagtg ggtcgagatc
     5101 gacaaccacg acgatctcgc ccgcggacgg gagatcgcgt gccagtactg acccggctca
     5161 ttccctcgcc ggtcgtggtg gacatccgcc cgggtgccct cgacgacctc ggcagtgtcc
     5221 tcgccgacga gcgcatctcg cagtcgggcc ggctggccat cgccgtcagc ggcggttccg
     5281 gtgcccggct gcgcgaacgg atcgccccct ctctgcccgg cgccagctgg tacgaggtcg
     5341 gcggcggcac catcgacgac gcggtgcggc tggcgagcga cataaaggcc ggccactacg
     5401 acgcggtcgt cggcctcggc ggcgggaaga tcatcgactg cgccaagttc gcggcggccc
     5461 gggtcggcct gccgctggtc gcggtcgcca ccaacctcgc ccacgacggc ctgtgctccc
     5521 cggtcgcgac cctggacaac gacgcgggcc gcggctcgta cggggtgccc aacccgatcg
     5581 cggtcatcat cgacctcgac gtgatccgcg aggcgcccgt ccggttcgtc cgctccggca
     5641 tcggcgacgc catctccaac atctccgcgg tcgcggactg ggagctggcg agccgggtca
     5701 acggagagaa gatcgacggt ctggccgccg ccatggcccg ccaggccggc gaggcggtgc
     5761 tccggcaccc cggcggagtc ggcgacgacg gcttcctcca ggtgctcgcc gaggcgctgg
     5821 tcctcaccgg catcgccatg tccgtgtcgg gcgactcccg cccgtcctcc ggcgcctgcc
     5881 acgagatcaa ccacgccttc gacctgctct accccaagcg cgccgccgcc cacggcgagc
     5941 agtgcggcct cggtgccgcc ttcgcgatgt acctgcgcgg cgcccacgag gagtcggcgt
     6001 acatggcaga ggtgctgcgc cggcacgggc ttccggtgct gccggaggag atcggcttca
     6061 cggtggacga gttcgtccgc gcggtggagt tcgcccccga gacccggccc ggccgctaca
     6121 cgatcatcga acacctcgac ctcaagacga accagatcaa ggacatctac gccgactatg
     6181 tcaaggccat cggtagctga actccgtccg gtcgtccacc ccgcgggggt gaaggaccgg
     6241 cgcagcggtg agcactgggc gggacgcctc tacatgcgcg aggtgtccct gcgcgtcgac
     6301 cgctacctgg tgaacaccag ggtcacgccc aaccagctca cgtacctgat gaccgtctgc
     6361 ggggtgctcg cggccccggc cctgctggtg ccggggatcg cgggcgccgt gctcggtgtg
     6421 gtcgccaccc agctgtacct gctgctggac tgcgtcgacg gcgagatcgc ccgctggaag
     6481 aagcagtact cgctcggcgg ggtctacctg gaccgcgtcg gcgcctacct caccgacgcg
     6541 gccgtcctcg tcggcctcgg cctgcgcgcc gccgacctgt ggggcaccgg ccgtatcgac
     6601 tggctgtggg ccttcctggg caccctcgcc gcgctcggcg ccatcctgat caaggccgag
     6661 accgacctgg tcggcgtcgc ccgccaccag accggcaggc cgccggtgca ggaggccgcc
     6721 tccgagctgc gttcctccgg catggcgctg gcccggcggg ccgcctcggc gctcaagttc
     6781 caccggctga tcctcggcat cgaggcctcg ctgctcatcc tggtcctcgc gatcgtggac
     6841 caggcccgcg gcgacctgtt cttcacccgc ctcggcacgg ccgtcctcgc cggcatcgcg
     6901 atgctgcaga ccctgctgca cctggtgtcc atcctcgcct ccagcaggct gaagtgagcg
     6961 cgcccatgaa ggtcggcgcc gtcatcatca ccatgggaaa ccggcccgag gagctgcggg
     7021 ccctgctgga ctccgtcgcc aagcaggacg gcgacccggt ggaggtggtc gtcgtcggca
     7081 acggctcgcc cgtcccggac gtccccgagg gcgtacggac ggtggagctg cccgagaacc
     7141 tcggcatccc cggcggccgc aacgtcggca tagaggcctt cgggcccggc ggccgcaacg
     7201 tcgacatatt gctcttcctc gacgacgacg gcctgctcgc ccggcacgac accgccgagc
     7261 tgtgccggga ggccttcgcg gccgacccgg agctcggcat catcagcttc cgcatcgccg
     7321 accccgacac cggcgagacg cagcgccggc acgtaccgag gctgcgcgcc tccgacccga
     7381 tgcgctcctc ccgggtcacc accttcctcg gcggcgccaa cgccgtccgc acccgcgtct
     7441 tcgccgaggt cggcgggctc ccggacgagt tcttctacgc gcacgaggag accgacctgg
     7501 cctggcgcgc cctcgacgcc ggctggatga tcgactaccg gtccgacatg gtgctgtacc
     7561 acccgacgac cgcgccctcg cggcacgcgg tctaccaccg catggtcgcc cgcaaccgcg
     7621 tctggctcgc ccgccgcaac ctgcccgccc tcctggtccc ggtctacctg ggggtctggc
     7681 tgctgctcac gctgctccgc cgcccctcgg ggccggccct gaaggcatgg ttcggcggct
     7741 tccgggaagg ctggaccacg ccctgcggcc cgcgccgccc gatgcgctgg cgtacggtgt
     7801 ggcgactcac ccgactgggc cgtcccccgg tcatctgaca agctcgtccc tgtgcgccgg
     7861 cgcgcccgtg cgcacggcag gacgaacgcg aacccgaaga cgaaagtttc cacacctgtg
     7921 agtgagacca cgcacgacgg cacggtcacg gtgaccgcgg ccccgtcgcc cgacgaggga
     7981 ctgacggcgg ccgagctcgc cgaaaagtac gggctctccg tgagcggcgc ccggccctcg
     8041 ctcgtggagt acgtccgtca gctctggggc cgccgccact tcgtcctcgc cttctcccag
     8101 gcgaagctga ccgcgcagta cagccaggcc aagctcggcc agctctggca ggtggccacg
     8161 ccgctgctga acgcggccgt gtacttcttc atcttcgggc tgatcctgca cgcgagccgc
     8221 ggcatgtccc gggacgtgta catcccgttc ctggtgaccg gcgtcttcgt gttcaccttc
     8281 acccagagct cggtgatgtc cggcgtccgc gcgatctccg gcaacctcgg cctggtgcgc
     8341 gccctgcact tcccgcgcgc cgcgctgccc gtctccttct cgctccagca gctccagcag
     8401 ctgctgttct cgatgatcgt gctgttcgtc gtggcgatcg gcttcggcag ctaccccagc
     8461 ccgtcctggc tgctgatcgt gccggtgctg gtgctgcagt tcctgttcaa caccggcctc
     8521 gcgctgatcg tggcccgcat gggtgccaag acgccggacc tcgcgcagct gatgccgttc
     8581 gtcctgcgca cctggatgta cgcgtccggc gtgatgttct ccatcccggt catgctgcag
     8641 gacaagccgc agtggatcgc gacggtgctg cagtggaacc cggcggccat ctacatggac
     8701 ctgatgcgct tcgccctgat cgacggctac ggtgccgaga acctgcccgc ccacgtctgg
     8761 gccgcggccg gcggctgggc cgtgctcttc gccgtgggcg ggttcgtgta cttctggaag
     8821 gcggaggaga ggtacggccg tggctgagca gaacgccggg caggacgcgc aggagcgtcg
     8881 ccccaccgtc atcgcggacg acctgcacat cgtctaccgg gtcaacggcg ccaagaccgg
     8941 caagggcagc gcgacggcgg ccctgagccg gatcctcagg cggggctcgg acgacgcggc
     9001 gcgcggggtg cgcaaggtgc acgccgtgcg cggtgtgtcc ttcgtcgcct accgcggcga
     9061 ggccatcggt ctgatcggct ccaacggctc cggcaagtcc acgctgctgc gcgccatcgc
     9121 cggcctgctg cccgcggaga agggcaaggt ctacaccgac ggccagccct ccctgctggg
     9181 tgtcaacgcg gccctgatga acgacctcac gggcgagcgg aacatcatcc tgggcggtct
     9241 cgccatgggc atgtcgcgcg agcagatcaa ggagcgctac caggacatcg tcgacttctc
     9301 ggggatcaac gagaagggcg acttcatcac cctgccgatg cgcacgtact cctccggcat
     9361 ggcggcgcgc ctgcgcttct ccatcgccgc cgccaaggac cacgacgtcc tcatgatcga
     9421 cgaggcgctg gccaccggcg accgcaagtt ccagaagcgc tccgaggagc gcatccggga
     9481 actgcgcaag gaggccggaa cggttttcct ggtcagccac aacaacaagt ccatccgcga
     9541 cacctgcaac cgcgtgctgt ggctggaacg cggtgaactg cgcatggacg gacccaccga
     9601 cgaggtcctg aaggagtacg agaagttcac gggcaagtga cgcgtttcgg ccagggcccc
     9661 gccgggactt ctccggcggg gccctgcgtc tgcaaaggaa gcgtcaactc ggcctggcgt
     9721 aaggaatctt ggagccaatc ggtgtgttgt tgtgatgtgc aggacacccc gacggtccgt
     9781 gccgcgttgt acaacgtaag ctgtaccggt gccggaaacc ggcaagtggg gcgataatgc
     9841 gcgacaccct gcggcgggac gaccccgcgc ggtgcggggc ggcgtgtccg aaatagtgtg
     9901 tattgggtcg gcagtgtaga acgggagatg tgacggcaat ggctacggaa actcccctgc
     9961 tcagcgcagc atgtgccgtc ccagccccgg gcagcgcccg atgacggcca ccggcacggc
    10021 gccagacctg gaacgcgcca ctctggacaa ggccgcgggc gagaacttcc ccgtggctcc
    10081 cttcttcctg cccagggcct ggcgcgagga cctcatggcc gtctacggct tcgcccgcct
    10141 cgtggacgac atcggcgacg gcgacctcgc ccccggcggc gccgacgccc ggctgctcgg
    10201 cctgtcgccc gccgctgccg cggaccggcc ggccctcctc gacgccttcg agaccgacct
    10261 gcgccgcgtc ttcggcggca ccccgcgcca cccgctgctg cgccgcctgc agcacaccgt
    10321 ccgccgccgc gccctcaccc ccgagccgtt cctcgggctg gtcgccgcca accgccagga
    10381 ccagctcgtc acccgctacg agacctacga cgacctcctc gcctactgcg aactgtccgc
    10441 caaccccgtc ggccgcctcg tcctcgccgt caccggcacc tcgacccccg agcggatccg
    10501 gctgtccgac gcgatctgca cggcgctgca gatcgtggag cacctccagg acgtcgccga
    10561 ggacctcggc cgcgaccgga tctacctccc cgccgaggac atgaagcgct tccacgtcca
    10621 ggaagcggac ctcgccgcga aaaccgcgag cgcatcggtg cgcgccctgg ttgcatacga
    10681 ggcgcaacgt gcccgcgatc tgctggatga aggcgccccc ctggtgggta gcgtccacgg
    10741 aaggctgaag ctgctgctcg cggggttcgt ggcgggggga agggcggcga tccgggcgat
    10801 cgccgccgcc gaatacgacg tacttcccgg cccgcccaga cccggcaagg tccggttgct
    10861 gcgcgaggcg ggcgcgatcc tgcgaggaga ggggtgatcc ggaccgtgga gtctccgccg
    10921 cacgtgtccg cgccggtact cgccgcctac agctactgcg aggccgtgac cgggcagcag
    10981 gcccgcaact tcgcgtacgg catccggctg ctgccgacgg ccaagcgccg cgccatgtcg
    11041 gcgctgtacg cgttctcccg gcgcgtggac gacatcggcg acggcgacct ggccggcgag
    11101 gtgaagctgg cgcgcctgga ggacacccgg gcgctgctcg cccggatccg cgagggcgag
    11161 gtggaggagg acgacaccga cccggtggcc gtcgccctca gccacgccgc ggacgccttc
    11221 ccgatcccgc tcggcggcct cgacgagctg atcgacggcg tccagatgga cgtgcgcggg
    11281 gagacctacg agacctggga cgacctgaag gtgtactgcc ggtgtgtcgc cggtgccatc
    11341 ggacgcctct cgctcggcgt cttcggcacc gaaccgggcg cccgcggcgc cgagcgcgcg
    11401 gccgagtacg ccgacaccct gggcctcgcc ctgcagctca ccaacatcct gcgcgacgtc
    11461 cgcgaggacg cggcgggcgg ccgtacctac ctgcccgccg acgacctcgc caagttcggc
    11521 tgctcggccg ggttcgacgg gccgaccccg ccggagggct ccgacttcgc cggcctcgtc
    11581 cacttcgaag tgcgccgcgc ccgcgccctg ttcgccgagg gctaccggct gctgcccatg
    11641 ctcgaccggc gcagcggcgc ctgcgtggcc gcgatggccg gcatctaccg ccggctgctg
    11701 gaccgcatcg agcgcgaccc cgaggccgtg ctccgcggcc gggtctcgct gcccggccac
    11761 gagaaggcct acgtcgccgt gcgcggcctg tccgggctcg acacccggca cgtgacccgc
    11821 cacgtctccc ggcgttccgt ccggaggcgc gcctgatgca gcgcaccgca ccagagccgg
    11881 ccggaccgga cggcatgcga caggcaaccc tcccctgcgg cgtggcgtcc ctgactgcga
    11941 cggcggagcg tgcacccttc actctctacg ccgagcaggt ccggagcgcc ccgaaggggc
    12001 gcggggcggt atccggcatg cggctcccgc cgcgtgggga cgaccagcca cgacgggccg
    12061 gcagacgacc gacggcccat cacggtgccg cccgcgcagc gctcgcacgg aaggacgcac
    12121 gatgagcgac gggtcatccc ccgcaccggc gcgggccggc accccgcgca cggcaggccg
    12181 cagcgcggtc gtggtcggcg gcggcctcgc cgggatcacc gcggcgctcg ccctcgccga
    12241 cgcaggcgtc cgggtcaccc tgctcgaagg caggcccagg ctgggcggcc tcgccttctc
    12301 cttccagcgc ggcgaactga ccgtcgacaa cggccagcac gtgtacctgc gctgctgcac
    12361 cgcataccgc tggttcctcg accggatcga gggtgcggcg ctggcaccgc tgcaggacca
    12421 cctggacgtg cccgtcgtcg acgtcgccaa gcccgagggg cggcggctcg gcaggctgcg
    12481 gcgcgacccg ctgcccgtgc ccctccacct ggggcgcagc ctggccgcct atccgcacct
    12541 ctcgctcgcc gagcgcgcgg ccgtcgggcg tgccgcgctc gcgctgaagg ggctcgacct
    12601 cgccgatccg gccctggaca cccaggactt cggcagctgg ctggccgcgc acggccagtc
    12661 ggcacgcgcc gtcgaggccc tgtgggacct ggtcggcgtc gccaccctca acgcggtcgc
    12721 gggcgacgcc tcgctggggc tcgccgcgat ggtgttcaag accggtctgc tgtccgaccc
    12781 gggagcggcc gacatcggct gggcccgcgt cccgctgggc gaactgcacg accggctggc
    12841 ccgcaaggcg ctcgactccg cgggcgtgcg taccgaggtc cgtacacgcg tcacctccgt
    12901 ctccttcaac gagaacggga cgtggagcgt tcaggttccc ggcgagaacc tcgacaccga
    12961 cgcggtcgtc ctcgccgtgc cccagcgcga ggcccacgac ctgctgccgc ccggcgccct
    13021 ggacgcgccc gagcggctgc tggagatcgg caccgcgccg atcctgaaca tccatgtgct
    13081 ctacgaccgc aaggtgctcg cacggccctt cttcgccgcc ctcggcaccc ccgtccagtg
    13141 ggtcttcgac cgcacggacg cctccgggct cggctcggga cagtacctgg cgctgtccca
    13201 gtcggccgcg caggacgaga tcgacacacc ggtcgccgag ctgcgcgagc gctacctgcc
    13261 cgagctggaa cggctcatcc cgggtacgcg cgctgccgcc gtactggatt tcttcgtgac
    13321 ccgggagcgc acggccacgt tcgcccccgc ccccggcgtc gggcggctgc ggcccggcgc
    13381 ccgcaccaag gcccccggcc tgtacctggc cggagcgtgg accgccaccg ggtggcccgc
    13441 gaccatggag agtgcggtcc gcagcggagt gagcgcggcc gacgccgccc tcagcgccct
    13501 gggccggccc cgcccccgtc acctcttcga gttcgaggag gcggcctgat gtccgatcag
    13561 caggcggcac gcccccgcac ccccggcacc gcaacaagag gagagactgt gcccactgtg
    13621 cccccggcct cgacgcccgc tccacgggcc gcggtggacg tcaccgcgct gctggagcgc
    13681 ggccggaccc tggccacacc ggtgctgcgc gcggccgtcg accgcctggc gccccccatg
    13741 gacaccgtcg ccgcctacca cttcggctgg atcgacgccg ccggcaaccc cgccgacggc
    13801 gacggcggca aggccgtccg ccccgcgctc gccgtgctct ccgccgaggt caccggcgcc
    13861 gcacccgagg tgggcgtccc cggcgcggtc gccgtcgaac tcgtgcacaa cttctcgctg
    13921 ctgcacgacg acctgatgga cggcgacgag cagcgccggc accgcgacac cgtctggaag
    13981 gtgcacggcc ccgcccaggc catcctggtc ggcgacgccc tgttcgccct cgcgggcgag
    14041 gtcctgctgg agctcggcac cgtcgaggcc ggccgcgcca cccgccgcct gaccaccgcc
    14101 acccgcgccc tgatcgacgg tcaggcccag gacatctcct acgagcaccg cgaccgggtc
    14161 agcgtcgagg agtgcctgga gatggagggc aacaagaccg gcgccctgct cgcctgcgcc
    14221 tcctccatcg gcgcggtcct cggcggcgcg gacgacgcca ccgccgacgc gctggaacgg
    14281 tacggctacc acctcggcct cgccttccag gccgtggacg acctgctcgg catctggggc
    14341 gacccggagg ccaccggcaa gcagacctgg agcgacctgc gccagcgcaa gaagtccctg
    14401 ccggtggtgg cggcgctcgc ggccggcggc cccgcctccg agcagctcgg cgagatcctc
    14461 gccgccgacg ccaagagcag cgacttccag aacttctccg aggaggagtt cgcggcccgc
    14521 gccgcgctca tcgaggaggc cggcggccgc gagtggacgg ccggggaagc gcgccgtcag
    14581 cacaccgtcg ccatcgaagc cctcgacgcc gtcgacatgc ccgaccgggt gcgggactcc
    14641 ttcacggcgc tcgccgactt cgtcgtcgta cgaaagcgat gatcacgatt ggcttgataa
    14701 gcctcgcgta gtcgccggcc ggtgcccgaa gggttcagga caccggccga cggcggaccc
    14761 acagcagcac gactcgcacg actgcacgaa ggggaagcca tgacagcgac gaccgacgga
    14821 agcaccgggg cgaccttgcc gtcccgcgct gccgcggcca gcgacaccac actcatcacc
    14881 cccgagacgg ccggggtaca agaagccgcc gcacgcgccg cccggcgcgc caccgactac
    14941 ctgctcgcca ggcaggacgc ccagggctgg tggaagggcg acctggagac caacgtcacc
    15001 atggacgccg aggacctgct gctccgtcag ttcctgggca tcctggagga ggacaccgcg
    15061 caggccgccg cgaagttcat ccgcggcgag cagcgcgagg acggcacctg ggccaccttc
    15121 tacggcggac ccggcgaact gtccaccacc gtcgaggcgt acgtcgccct gcgcctggcc
    15181 ggcgacgcgc ccgacgaccc gcacatggcg aaggcctccg cctggatccg cgagcgcggg
    15241 ggcatcgcgg ccgcccgggt cttcacccgg atctggctcg ccctgttcgg ctggtggaag
    15301 tgggaggacc tgcccgaact ccccccggag ctgatctact tccccacctg gttcccgctg
    15361 aacatctaca acttcgggtg ctgggcacgg cagaccatcg tcccgctcac catcgtctcc
    15421 gccaagcgcc cggtgcgccc ggcccccttc gccctggacg agctgcacac cgacccggcc
    15481 aacccgaacc cgccgcagcc gctcgccccc gtggccagct gggacggcct cttccagcgg
    15541 ctcgacaagg tggtccgcgg ctaccgcagg ttcgccgtgc gcaggctccg cagggccgcg
    15601 atgaactcgg cggcccgctg gatcatcgaa cggcaggaga acgacggctg ctggggcggc
    15661 atccagcccc cggccgtgta ctcggtcatc gccctgcacc tgctcggcta cgacctcgag
    15721 cacccggtgc tgcgcgaggg cctcgcctcg ctcgaccgtt tcgccgtctg gcgcgaggac
    15781 ggcgcccgga tgatcgaggc ctgccagtcc ccggtctggg acacctgcct ggccaccatc
    15841 gccctcgtcg acgccgggct tcccgtcgac catccgcaac tggtcaaggc ggccgactgg
    15901 atgctcggcg aggagatcgt ccggcccggt gactgggccg tacgccgccc gcacctcccg
    15961 ccgggcggct gggcgttcga gttccacaac gacaactacc cggacatcga cgacaccgcc
    16021 gaggtcgccc tcgcgctgcg ccgggtccgg caccacgacc cggagcgcgt ggacagggcc
    16081 atcgggcggg cggtgcgctg gaacctcggc atgcagtcga agaacggcgc ctggggcgcc
    16141 ttcgacgtgg acaacaccag cccgttcccc aaccggctgc cgttctgcga cttcggcgag
    16201 gtcatcgacc cgccgtcggc cgacgtcacc gcgcacgtcg tggagatgct cgccgccgag
    16261 ggcctggccc aggacccgcg cacccggcgt ggcatcgact ggctgctcgc cgagcaggag
    16321 cccgacggtt cgtggttcgg ccgctggggc gtcaactacg tctacggcac cgggtccgtg
    16381 gtgcccgccc tcacggcagc cggtctgccc ggcacgcatc cggcgatccg gcgggccgtt
    16441 gcctggctgg agagcgtcca gaacgacgac ggcggctggg gcgaggacct gcgctcctac
    16501 aagtacgcca aggagtggag cggccggggc gcctccaccg cctcgcagac cgcgtgggcg
    16561 ctgatggcgc tgctcgcggc gggggagagg gagtccaagg ccgtcgagcg cggcgtccag
    16621 tggctggccg ggacccagcg ggaggacggc acctgggacg agccgtactt caccggcacc
    16681 ggcttcccct gggacttctc catcaactac cacctgtacc gccaggtgtt cccgctcacc
    16741 gcgctcggcc ggtacctgca cggcgatccc ttcgagcgcg acctgctcac caggaagccg
    16801 ctgtccgggg ccaaggtgag ctgaggtgaa caaccagccc gccccggcac cgctgctgat
    16861 cgcctgcgcg ctcggcatcg agcacctcgc cctgcgcacc ggcgaccaca gcggtgccgg
    16921 cgggccggtg accttcgtcc gcacgggcat gggcccccgt gcggcggaac gctccgtcac
    16981 ccggcacctg gccggccagg cggcggccga cacggccgtg ctggccaccg gcttctgtgc
    17041 cggactcgcc cccggtatgc accccggcga cctggtcgtc gccgaggaga cccgggaccc
    17101 gcgcgggacc gtcccgtgcg tgggcaccga actgctggtc aaggaactcg tgcgcctgct
    17161 gcccggacgc acggtccaca ccggcccgct caccggctcc gaccacgtcg tccggggacc
    17221 cgagcggtcc gatctgctcg ccaccggcgc gatcgcggtc gacatggagt cggcggccac
    17281 gctgctggcc gccgtccgca cgggcgaacg cccggtcgcg gccgtccggg tggtcgtgga
    17341 cgctcccgaa cacgaactcg tccggatcgg cacggtacgc ggtggaatat ccgccttccg
    17401 cgttcttcgt tccatccttc ctgctttttt cgaatggcac cgttctttgc tgctcccccg
    17461 gaggtgagcc agatggccat gccgttgcgt cagtccatca aggtcgctac gtacctggct
    17521 gaacagaagc tccgcaggcg ggacaagttt ccgctcattg tcgagctgga accgctgttc
    17581 gcctgcaatc tgaagtgcga gggctgcggc aagatccagc acccggccgg tgtgctcaag
    17641 cagcgcatgc cggtcgccca ggcggtgggt gcggtgctgg agtccggtgc gccgatggtc
    17701 tccatcgccg gcggcgagcc gctgatgcac cctcagatcg acgagatcgt gcggcagttg
    17761 gtggcgaagc ggaagtacgt cttcctgtgc accaacgcga tgctgctgcg caagaagatg
    17821 gaccagttca ccccctcgcc ctacttcgcc ttcgccgtgc acatcgacgg cctgcgtgaa
    17881 cggcacgacg agtccgttgc gaaggaaggc gtgttcgacg aggcggtgga ggccatcaag
    17941 gaggccaagc ggcgcggctt ccgggtgacc accaactcca ccttcttcaa caccgacacc
    18001 ccgcagacca tcatcgaggt gctcaacttc ctcaacgacg acctcaaggt cgacgagatg
    18061 atgatctcgc ccgcctacgc ctacgagaag gcccccgacc aggagcactt cctcggcgtc
    18121 gagcagaccc gcgaactgtt caagaaggcc ttcgcgggcg gcaaccgcag gaagtggcgg
    18181 ctcaaccact ccccgctctt cctggacttc ctggagggca aggtcgactt cccgtgcacc
    18241 gcgtgggcga tcccgaacta ctcgctcttc ggctggcagc gcccctgcta cctgatgagc
    18301 gacgggtacg tgccgacgta ccgcgaactc atcgagaaga ccgactggga caagtacggc
    18361 cgcggcaagg acccgcgctg cgccaactgc atggcgcact gcggctacga gcccaccgcc
    18421 gtcctggcca ccatgggctc cctgaaggag tcgctgcggg cgatgcgcga gaccgtctcc
    18481 ggaaaccggg agtgaggcga tgaccgccgt ccccttgggc gttcccgagg taccgggccg
    18541 tccggtcgcg ccgcggcgcc tgtcgcggca ggtccaggtc gggccggtgg cggtcggggg
    18601 cggagccccg gtgtcggtgc agtcgatgac gacgacccgt acgtccgaca tcggcgccac
    18661 cctccagcag atcgcggaac tcaccgcgtc cggctgccag atcgtccgcg tcgcctgccc
    18721 cacgcaggac gacgcggacg ccctcgcgac catcgcccgc aagtcgcaga tcccggtgat
    18781 cgcggacatc cacttccagc ccaagtacgt gttcgcggcc atcgaggccg gctgcgccgc
    18841 ggtccgtgtg aaccccggca acatcaagaa gttcgacgac caggtggagg agatcgcgcg
    18901 ggccgccagg gaccacggca cgccggtccg gatcggcgtc aacgccggct ccctggaccg
    18961 gcgcctgctc cagaagtacg gcaaggcgac ccccgaggcc ctcgtcgaat cggccctctg
    19021 ggaggcgtcc ctcttcgagg agcacgactt ccacgacatc aagatctcgg tcaagcacaa
    19081 cgaccccgtc gtcatgatcg aggcctaccg ccagctcgcc gagcagtgcg actaccccct
    19141 gcacctgggg gtcaccgagg ccggcccggc gttccagggc acgatcaagt cggccgtcgc
    19201 cttcggggcg ttgctctcgc gcggcatcgg ggacaccatc cgggtctccc tgagcgcacc
    19261 gcccgccgag gaggtcaaag tcggcatcca gatcctggag gcgctggggc tcaggcagcg
    19321 gcggctggag atcgtctcct gcccgtcctg cggccgggcc caggtggacg tgtacaagct
    19381 cgccgaggag gtcaccgctg gtctggacgg catggaagtg ccgctcaggg tcgcggtgat
    19441 ggggtgcgtg gtcaacggtc cgggggaggc ccgggaggcc gacctcgggg ttgcctcggg
    19501 caacggcaag gggcagatct tcgtcaaggg cgaggtcgtc aagaccgtcc ccgagtcgaa
    19561 gatcgtggag accctcatcg aggaggccat gaagctcgcc gagcggacga gccccgcaga
    19621 ccaagtgagt tgaggcaagg cacggaccga gagggggccc gagcgtgacc attctggaga
    19681 acatccgggg accacgcgac ctgaaggcgc tgtccgaggc ggaactcggt gaactgtccg
    19741 aggagatacg tgagttcctg gtgcacgcgg tgtcgaggac cggcggtcac ctcgggccca
    19801 acctgggcgt ggtggaactg tccatcgcgc tccaccgggt cttcgagtca ccggtcgacc
    19861 gcatcctgtg ggacaccggc caccagagct atgtccacaa gctgctgacc ggacgtcagg
    19921 acttctcgaa gctgcgcggc aagggcgggc tgtccggcta cccctcgcgc gaggagtccg
    19981 agcacgacgt catcgagaac agccacgcct ccaccgcgct gggctgggcc gacggcctcg
    20041 ccaaggccca ccaggtgctg ggggagaagg gccacgtggt cgcggtcatc ggcgacggcg
    20101 cgctgaccgg cggcatggcc tgggaggcgc tcaacaacat cgccgcggcc agggaccggc
    20161 cgctgatcat cgtcgtcaac gacaacgaac gctcctacgc ccccaccatc ggcggactcg
    20221 ccaaccacct ggcgaccctg cgcaccaccg acggctacga gaaggtcctc gcctggggca
    20281 aggaggtgct ccagcgcacc ccggtcgtcg gcaccaccct gtacgagtcc ctgcacggcg
    20341 cgaagaaggg cttcaaggac gccttcgccc cgcagggcat gttcgaggac ctgggcctga
    20401 agtacctcgg tccgatcgac ggccacgaca tccaggccgt cgagtccgcg ctgcgccgcg
    20461 cgaaacgttt ccacggcccc gtcctggtgc actgcctcac cgagaagggc cgcggctacg
    20521 agcccgccct cgcgcacgag gaggaccact tccacaccgt cggcgtgatg gacccgctga
    20581 cctgcgagcc gctcgccccg tccaacggac cctcctggac ctcggtgttc ggcgaggaga
    20641 tggtacggat cggggaggag cgcgaggacg tcgtggcgat cacggcggcc atgctgcatc
    20701 cggtgggtct cgccggattc gccgaacgct tcccggaccg ggtgtgggac gtcgggatcg
    20761 ccgagcagca cgcggccgtc tccgcggccg gtctcgccac cggcgggctg cacccggtcg
    20821 tcgccgtcta cgccaccttc ctcaaccggg ccttcgacca gctgctcatg gacgtcgccc
    20881 tgcaccgctg cggggtcacc ttcgtcctgg accgggccgg cgtgaccggc accgacggac
    20941 cctcgcacaa cggcatgtgg gacatgtccg tcctccaggt cgtcccgggc ctgcggatcg
    21001 ccgcgccgcg cgacgccggc cagctgcgcg cccagctgcg cgaggcggtc gccgtggacg
    21061 acgcccccac cctggtgcgc ttcccgaagg agtccgtcgg cccgagcgtc ccggctctcg
    21121 accggctcgg cggcatggac gtgctgcacc gcgccggccg ccccgaggtg ctgctggtgg
    21181 cggtcggcgt gatggcctcc gtgtgcctcc aggccgccga gctgcttgag gcccgcggca
    21241 tcggctgcac cgtggtggac ccgcgctggg tgaagccggt cgaccccgcg ctgccgggac
    21301 tcgcggccga gcaccgcctg gtggccgtgg tcgaggacaa cagccggtcc gcgggcgtcg
    21361 gttcggcggt ggcgctggct ctgggagacg ccgacgtgga cgtgccggta cggcggttcg
    21421 ggatcccgga gcagttcctc gcgcacgcca aacgcagcga ggtgctggcc gacatcggcc
    21481 tcacgccggt ggagatcgcc gggcggatca gtggcagtct ggccgtcggg gacgtgggcg
    21541 gcaccgtcaa ggagagtgaa tgaccagcga gttcgacctc ggcgccctgc tcgccgagcg
    21601 cggagccgaa cgctacgagc tgcacgcgaa gcacctcaac ccgcagctgc cgcggatgct
    21661 gcacaccatc ggcttcgaca aggtctacga gcgcgccgag ggcgcccact tcttcgacgc
    21721 ggagggcaac gactacctgg acatgctcgc cgggttcggg gtgatgggcc tgggccgcca
    21781 ccacccggtc gtccgcaagg cgctgcacga cgtcctggac ctggacctcg ccgacctcac
    21841 ccgcttcgac tgccagccgc tgcccggcct gctcgccgag cggctgctga cccacagccc
    21901 gcacctggac cgggtgttct tcggcaacag cggcaccgag gcggtcgaga cggccctgaa
    21961 gttcgcccgg tacgccaccg gcaggccacg cgtcctctac tgcgaccacg ccttccacgg
    22021 tctgaccacc ggctccctgt cggtcaacgg cgagcgcggc ttccgcgacg ggttcgcccc
    22081 gctgctgccc gacaccgccg tgccgctcgg cgatctcgac gccctggccc gggagttgaa
    22141 gaagggcgac gtcgccgcgc tgatcgtgga gccgatccag ggcaagggcg tgcacgaggc
    22201 gccgcccggc tatctgcggg ccgcgcagga gctgctgcac cggcacaagg cgctgctcat
    22261 cgccgacgag gtgcagaccg gcctcggccg caccggcgac ttctacgcct accagcacga
    22321 ggacggtgtc gaacccgacc tggtgtgcgt ggccaaggcc ctgtccggcg gctatgtgcc
    22381 cgtcggcgcc accctgggca aagagtggat cttcaagaag gtctactcgt ccatggaccg
    22441 ggtgctggtg cactcggcga gcttcggctc caacgcccag gcgatggcgt gcgggctcgc
    22501 cgtgctgtcg gtcatggaga acgagcagat cgtggccggc gtgcgccgga cgggcgagct
    22561 gctgaagtcc cggctcaccg cgctgatcga cacgtacgag ctgctcgccg acgtccgcgg
    22621 ccggggcctg atgatcggca tcgagttcgg caagccgtcc tcgctgaagc tgcgcagccg
    22681 ctggaccatg ctgcaggcgg cccgcaaggg cctgttcgcg cagatggtcg tcgtaccgct
    22741 gctgcagaag caccggatcc tcacccaggt ctccggcgac cacctggagg tgatcaagct
    22801 catcccgccg ctggtcgtcg acgagacgga cgtggagcgc ttcgtggagg ccttcaccgc
    22861 cgtgatggac gacgcgcaca gcggcggcgg cctgatgtgg gacttcggca agaccctgat
    22921 caagcaggcg gtggccaacc gctgaccgcg gcggcgggac tggggaatct ttgcctgtga
    22981 ggcaagaaaa ttgccccacg ggcaaggctg cggctcaatg gagacatgaa cgcctcagac
    23041 gccgcgccgg cgccgggccc agccccggac gacggcctgt ccgccgtcgc gccgcagctg
    23101 cgctccctgc gccggcgcgc cggtctcaca ctggaggccg cggcccgcgc cgccgggctc
    23161 tcgccggccc atctgtcccg cctggagacc ggacaccgcc agccgtcgct gccgatgctc
    23221 ctcgcgctcg cccgtatcta cggtacgacc gtctccgagc tgctcggcga gacggtcgcc
    23281 gaccgggacg cgatcgtgcg ggccgccgac atggagccga cccgggcggg cggctggacg
    23341 tacgtccagg ccggcgcgcc cggccgcggc atgcaggccc tgcgggtgcg ggtgccgtac
    23401 ggctcgcagg gcgacatcgt gcgcgtccac cccggcgagg agtggctcta cgtcctcacc
    23461 gggcggctgc ggctgcggct cggcgacacc gcgcacctgc tcggacccgg tgacagcgcg
    23521 cacttcgact cgctcacccc gcaccgcctc gccgccgagg accacgacgg cgtggagctg
    23581 ctgttcgtcc acaccctgct gcagagcccc acggccacgc tgtgtctggg cgcgccgacc
    23641 ggagagctgc catgagcgac ttcgaggaga agttcccccg ttccctgtgg atccggctga
    23701 tcatctacat cgccctcggg cacgtcctgg ccgccttcct ctacctgctg ttcgcggtgg
    23761 gcggcaaggg ctgatcccgg tacccgggtc agtgcagcag gcgctcgcgc agccggtcgc
    23821 gggactcggc cgagaagccc aggccccgcg ccaggtacgt gtccacgtcg ccccaggtct
    23881 gctcgatgct cgtgaaggcc gcctccaggt actcggcgcg ggcgtcgaat agcgggtcga
    23941 gcagctccat cacctccggg gtgtacgcgg tgtcggcgct gccgctgcgg cggaccttgt
    24001 agcgccggtg cccggcggcc gactccaggt agtcggcgag gatcgcgtcc cgctccaccc
    24061 ccacggcgag cagcgtcacc gccacggaga tgcccgcgcg gtccttgccg gccgcacagt
    24121 gcatcagcgc gggcacgctg tcgtcggcga gcgcgtgcag cacacgggag tgctcggccg
    24181 tgcgctcggt gacgatcttc cggtaggagg cgatcatccg cgccgcgccc ttgccgtcgt
    24241 ccaggatcgc gcgcagctgg tcgaggtcgc cctcgcggac catcttccag aacgcggcgc
    24301 cgtccgccgg gtcgctcagc ggcaggttca cgtaccgcac gccgggcagc tcgacgtcgg
    24361 ggccctccag cttctggtcg gccgcgttgc ggaagtcgaa gaccgtgtgc aggcccaggg
    24421 aggcgaggaa ggccgcgtcc tcctgcgtcg cgtgcgcgag atggccgctg cggaagagga
    24481 ccccgtgacg cacccgccgt ccgtccacgg tcggcagccc gcccacatcg cggaaattgc
    24541 gcactccggc cagctccggc tcggtcgacg ggacctgctg cgtcacgggg gctcctcccg
    24601 gtcggtcgcc gccgtcgcgg ctcgtcggcg ggcgctcagt cgaccatacg gcatcgattt
    24661 cctcaggcaa tgagttgtcc acaggcattg ccagtggggt gcgcgcacct gatgatgttt
    24721 gcacttgcgc ggatctgttg gcacttgtga ggtctcgatg gtggacatcg ccgaaaacgg
    24781 tcgtacctgg ctcctgtcgg gccccaacag cagttatgcg ctgcatctca ccgacgcgga
    24841 cgagctgctg cacctccact gggggccgcg gatcgcgctc gtcgacgccg aggcgctcgc
    24901 ggtgcgctcg ctgcccggct actggccctt cgagtccccg ctcgacggcc gcgaggaata
    24961 ccccgtcgag ggcggacccc gcttcgtccg ccccgccctg tccgtccgga ccgaggagcg
    25021 gcgcggcacc gagtggcggt tcgtgtcgta cggcacggag ggcgacgaac tgcggctgcg
    25081 cttcgacgac gacggcgtgg ggatcacgct gcactaccgg atgcgcggcg acgtggtcga
    25141 gcgctgggtg accgtcgtga acggcggcca cacgcgcgtg gagctgctgc gggccgacgc
    25201 ggccacctgg acgctgcccg accgcgaggg ctggcggctg tcccagctgc acggccgctg
    25261 ggccgccgag tcccggctca ccgccgcccc cctcacctac ggcgagaagg tcatcggcag
    25321 tcgccgcggt cacaccggcc accagcacct gccctgggtc gccctcgaca ccgacgccac
    25381 cgaggagcgc ggcgaggtct acggctgcgc gctcggctgg tccggctcct ggcgcatcgc
    25441 ggtcgcccaa ctccctgacg cgcgcgtgca gatcaccggc ggtgccggcc acgacgactc
    25501 gggcctgctg ctcctcgcgc ccggggagtc gtacaccagc ccggtcttcg cgggcctgtg
    25561 gagcgacggc ggcttcggcg gcgcgagccg cgcctggcac gcctaccagc gcgcctacgt
    25621 catcccggac gccgaccggg accggcccgt gctgttcaac tcctgggagg ccaccttctt
    25681 cgacatctcc gaggagcagc agctcgcgct cgcccgccgg gccgccgaga tcggcatcga
    25741 gctgttcgtc gtcgacgacg gctggttcgg cgcccgcacc agcgaccgcg cgggcctcgg
    25801 cgactggacg cccaatcccg accgcttccc gcacggcctc aagcccctcg ccgaccaggt
    25861 gcacggcctg ggcatgcggt tcggcatctg ggtcgagccc gagatggtca accccgacag
    25921 cgacctgtac cgcgcccacc ccgactgggt gcagtaccaa ccgggacgta agcggacgga
    25981 actgcgcaac cagctcgttc tcaacctcgc acgcgaggac gtgcaggagt acctgtggga
    26041 gcggctgcac accctgctgt ccagcgcccc gatcgactat gtgaagtggg acttcaaccg
    26101 ctgcttcacc gacgccggct ggcccgggga gccgtacccg cagcgcctgt gggtggacca
    26161 cgtccgcgcc ctgtacgccc tgctggaccg gctgcgggcg gcccatccgg gggtcgcctt
    26221 cgaatcctgc tcgggcggcg gcggccggat cgacctcggc gtgctcggcc gcaccgacca
    26281 ggtgtggacc tccgacaaca ccgacccgct ggaccggctc gccatccagc acgggttcac
    26341 ccagatccat cccgcgcgcg tgatggcggc ctgggtcacc gacagcccca acacccagct
    26401 caacgggcgg gtcagctcac tgcggttccg gttcgtcagt gccatggcgg gcgtgctcgg
    26461 ggtgggcgga gacctgacgg agtggagcgc gcaggagctg gccgaggccc ggcggtgggc
    26521 ggagctgtac aaggagatcc gcccggtcgt acagcacggc gagctgtacc ggctgcgtcc
    26581 cccggcgggc ggcctgggtg ccgtgcagta cctccggggc gaggagaccg tcgtcctcgc
    26641 ctggctccag gcgcagcacc acggcgagcc ggtcccggcg gtgcggctgc gcgggctcga
    26701 cccgacagct tcgtacgaat gccgtgaaac gggcgaagtg catcgaggtg ccgtgctgct
    26761 gcaccacggg ctgcacaccg cactgaaggg cgacttggac gcgacggtca tccgactgcg
    26821 ccgc
//
