LOCUS       NZ_CP071839            29420 bp    DNA     linear   CON 20-APR-2024
DEFINITION  Streptomyces cyanogenus strain S136 chromosome, complete genome.
ACCESSION   NZ_CP071839
VERSION     NZ_CP071839.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces cyanogenus
  ORGANISM  Streptomyces cyanogenus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8773899)
  AUTHORS   Hrab,P., Ruckert,C., Busche,T., Ostash,I., Kalinowski,J.,
            Fedorenko,V., Yushchuk,O. and Ostash,B.
  TITLE     Complete genome sequence of Streptomyces cyanogenus S136, producer
            of anticancer angucycline landomycin A
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8773899)
  AUTHORS   Hrab,P., Ruckert,C., Busche,T., Ostash,I., Yushchuk,O.,
            Kalinowski,J. and Ostash,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2021) Genetics and Biotechnology, Ivan Franko
            National University of Lviv, 4 Hrushevskoho St, Lviv, Lviv region
            79005, Ukraine
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method :: Newbler v. 2.8; Canu v. 1.8; Unicycler v. 0.14
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 974878.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017526105.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 09:57:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,747
            CDSs (total)                      :: 7,656
            Genes (coding)                    :: 7,375
            CDSs (with protein)               :: 7,375
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 281
            CDSs (without protein)            :: 281
            Pseudo Genes (ambiguous residues) :: 0 of 281
            Pseudo Genes (frameshifted)       :: 129 of 281
            Pseudo Genes (incomplete)         :: 239 of 281
            Pseudo Genes (internal stop)      :: 25 of 281
            Pseudo Genes (multiple problems)  :: 104 of 281
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:56:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7283729
            Orig. end                         :: 7313149
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071839.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Bohdan Ostash, 4
            Hrushevskoho St., Lviv, 79005, Ukraine.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..29420
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /product="lanthipeptide-class-i"
                     /region_number="28"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..29420
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="lassopeptide"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22625
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22625
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12625](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12625
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(625..639)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     tRNA            1013..1097
                     /anticodon=(pos:7284775..7284777,aa:Leu,seq:gag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="S1361_RS32685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="S1361_32640"
                     /product="tRNA-Leu"
     gene            1013..1097
                     /locus_tag="S1361_RS32685"
                     /old_locus_tag="S1361_32640"
     gene            complement(1344..2153)
                     /locus_tag="S1361_RS32690"
                     /old_locus_tag="S1361_32645"
     CDS             complement(1344..2153)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="S1361_RS32690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="S1361_32645"
                     /product="hypothetical protein"
                     /protein_id="WP_208035473.1"
                     /transl_table=11
                     /translation="MKTQISHAVKHYNDDKVDRQGEFRGMQLVGGEFYCPLMPAPLITA
                     GATYIDSRTDEDRAHALNLIQSRKDYQTKIKEYGPAGDQRRQCPALGSHATVTCYRRPQ
                     PRPSTVVDLDAPTARTPAALSTIPRPKRDTPVYPDICRGKSITVPGTVLAEWRQKYPLF
                     TPLWQEAWSGLRSQNEGGNGNLKKSALDSIDNPQLRLPHGRVAQTLLNAVIIFVANLRA
                     IRRFLRDQGIQPRKAGTQSAATPPGEPFDPPQARPLPTEQVEPPPRE"
     gene            2278..2502
                     /locus_tag="S1361_RS32695"
                     /old_locus_tag="S1361_32650"
     CDS             2278..2502
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="S1361_RS32695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="S1361_32650"
                     /product="hypothetical protein"
                     /protein_id="WP_208035474.1"
                     /transl_table=11
                     /translation="MCEAAVEAQGAYDEGELSGDLMRAVGKPALGSALTAPAEGRCAAV
                     GSELAVAADRVAADEVTEQEEISRNRCQP"
     gene            complement(<2780..3157)
                     /locus_tag="S1361_RS32700"
                     /old_locus_tag="S1361_32655"
                     /pseudo=""
     CDS             complement(<2780..3157)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948683.1"
                     /locus_tag="S1361_RS32700"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32655"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKERRGHSAAGQSPFQRQSRRWRQTSRLYAGVSPSGKHHVIVDRH
                     GTPLAVSLTGGNRHDVTQLVPLLEAIPRIRGRRGRPRHKPKRLYADRGYDFRKYRRLLW
                     VRGIVPKIARRGAPIDRGARLG"
     misc_feature    complement(3221..3235)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.8"
                     /tool="antismash"
     gene            <3270..>3570
                     /locus_tag="S1361_RS32705"
                     /old_locus_tag="S1361_32660"
                     /pseudo=""
     CDS             3270..>3570
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056468.1"
                     /locus_tag="S1361_RS32705"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="S1361_32660"
                     /product="mobilization protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MWIAVRRADDHINVRCHPRPRRRHPCPDRMPRDRNRLRPPDPQRR
                     RPHRRPAPH"
     gene            complement(3933..5135)
                     /locus_tag="S1361_RS32710"
                     /old_locus_tag="S1361_32670"
     CDS             complement(3933..5135)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669443.1"
                     /locus_tag="S1361_RS32710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32670"
                     /product="cytochrome P450"
                     /protein_id="WP_208035475.1"
                     /sec_met_domain="p450 (E-value: 1.8e-22, bitscore: 78.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNTEQTGSVSSLLSEALVADPHGTYARLREAAPVHRTATPDGEP
                     MWLITRYAEARAALADPRLSLNKANAKTSGEYRSSMPPELDTHLLNMDPPDHTRLRRLV
                     AKAFTPRRVEGLRMRIQKLTDELLTTMTGPRVDLVHALAVPLPMSVICELLGIPETARL
                     DFRAWTDTLFSPAPGAATESRTAMRQMHQFLKSVIEEKRNSPTEDLLSALVQARDDRDV
                     LTEPELVSLAFLTLFAGYDNAVHLIGNTALSLLLHPRLLTAVRGGAVPIRSVVEETLRW
                     NPPFALAVRRFALEDVSIGNALIPAGSRVWVSIASANRDGREFPSPEVFDPTRTPTHLA
                     FGYGVHYCIGAPLARMEAEIAVWSLMKRFSELELAVGLNELEWWPTFHKRGLRSLPVMT
                     C"
     cand_cluster    5018..29420
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    5018..29420
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[15017:19420](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      15018..19420
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
     gene            complement(5132..6355)
                     /locus_tag="S1361_RS32715"
                     /old_locus_tag="S1361_32675"
     CDS             complement(5132..6355)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042915.1"
                     /locus_tag="S1361_RS32715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32675"
                     /product="MAB_1171c family putative transporter"
                     /protein_id="WP_208035476.1"
                     /transl_table=11
                     /translation="MLFNVVYGTLSLITWSAFAFKLRDLARDWRNKELQRLCLAIAMFA
                     APFGFAAPPVYVRVDALIGTPNISSLIIYTTVEVCLTSFLALLVSWSSAQSKVRLRHRL
                     ILGYALATVTTNWVLFFLGDATDTSHALDFDVHYAKTAYIWEFLLVHQTLYTVSMIGLI
                     RLCWRYSKIVGQPWLRRGLRIVTVGAVAGLGYCLPKVISLIWDKLGISPLGFVNSVVAP
                     MFASVSAALFAIGFTMPAWGVGLGRVMAWMSDYRTFHRRYPLWQAITRAFPEVVLVTPP
                     TSRRELARDLRFFLGRQVIEILDGEMRLRPHHDPEISRMTREVAANQNIPGDEADAVAE
                     AAQIAAALQARSTGHEASGGHGTDFDDAANGDLSKEGARLTLVADAFSTSPVIPAVLER
                     LQSAKTDA"
     misc_feature    complement(6339..6355)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.0"
                     /tool="antismash"
     misc_feature    complement(6350..6352)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6360..6893)
                     /locus_tag="S1361_RS32720"
                     /old_locus_tag="S1361_32680"
     CDS             complement(6360..6893)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="S1361_RS32720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="S1361_32680"
                     /product="hypothetical protein"
                     /protein_id="WP_208035477.1"
                     /transl_table=11
                     /translation="MNDRELRRYCADLVRQLDIPEPFNINALVDQIEERRGRAISLVPM
                     PLPADRGLCGMWVATSDVDYVIYQEEARKAHQGHIVLHEIGHMLCEHESTPAEEEEVSR
                     LLLPNIDPALVRTVLGRTCYDRSEERAAELVASLIPLQAANAAPRPTPSLSEDVVNLVS
                     HLERSLGRSSTPRT"
     gene            complement(7066..8028)
                     /locus_tag="S1361_RS32725"
                     /old_locus_tag="S1361_32685"
     CDS             complement(7066..8028)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="S1361_RS32725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="S1361_32685"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_208035478.1"
                     /transl_table=11
                     /translation="MTLARLEALLKERGMNRSQVLDIGELAAKAALPQNTVAVLLRGGH
                     TPADTVAARVSARIKILADAYLARTGKPMSDLAGSISRQLGVSSFWARQVCSGDKVPSV
                     ELLHGLVGFFGVEGGEAFFTAPAAEALNRVLLPMLAALQQTSGRPEVDGSATSPAEREA
                     AVPSPREADAENPPRPAQPPSAVPDLSARLNRLFAVMHPRGRETYTSHEVAETITAHGV
                     KITAAQVEELRHGTWTSPSPEQLDALASFFGVPVGYFVNDEVASQVSADLNLVETLKSQ
                     GIGPRQIALRAVADLDEEALAALVPVIQHLQRASKRQRM"
     misc_feature    complement(8726..8745)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.77"
                     /tool="antismash"
     misc_feature    9018..9032
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     misc_feature    complement(9120..9136)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.31"
                     /tool="antismash"
     gene            9152..9661
                     /locus_tag="S1361_RS32735"
                     /old_locus_tag="S1361_32695"
     CDS             9152..9661
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012610.4"
                     /locus_tag="S1361_RS32735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32695"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_208035479.1"
                     /transl_table=11
                     /translation="MTSVPHPPASSVDPAGRNIGAGAAPGAGSALYTRIGRKLKQEIVS
                     GVYAQGAYLPSSGELGKLYGANKNTVLRALRMLRAEGLIDFGRGRGAVVVHSARKVGLA
                     EISEQLRYVVNLADVSGIPRAAVVAAIHRIPPSQGPRPAGALPAAAARRGGAGRTAFRP
                     HGRGAA"
     misc_feature    9338..9340
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9695..9715)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.91"
                     /tool="antismash"
     gene            10001..11896
                     /locus_tag="S1361_RS32740"
                     /old_locus_tag="S1361_32705"
     CDS             10001..11896
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="S1361_RS32740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32705"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_208035480.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.6e-36, bitscore:
                     125.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSDWTPDSCGAVRMSPGSVCRWVGSDLWRTMSSHGESWFVVLPD
                     CEAGLAVASRLEEQRRNKAPKRVLHPSGRPLLIGSWGSAFVTTTRHGLQVAVIGSSSAD
                     EDGIAQRLAHERDIASAARKLAALRGDFHIVVAGGSRLRVRGTASGMRRVFHADTAGVT
                     VASNRADVVAGLVGAPLDEELLAVRLLDSVPHPLGDVPLWRGVHAVPPGFQLDTGPDGV
                     SRTRWWSPPEPRLGLEEGAALLRRELDLAVRVRTGAATTVSSDLSGGLDSTAVCAVAAA
                     AGAAPFALTMASRDPGDDDVHWAKLAAAGLKHAEHLVLPVDQVPLFYSGLLEVTGPVDE
                     PTPTILDQPRQLAGHDEMAVRGSELHLTGMGGDHVLWGHPAHVLQRLATEPFGALRHLR
                     AYRAQNRWSLRDALSVIGDRRSYGQWLVASADRLTAPRAAPHSADVLAWDVPPRMPGWA
                     TPDAVAAVRRRMRLAAQSAIPLGGTRAQHNELNILHHGTRVTRVLHQVSEQGGLPMASP
                     FFDDHVIEASWSVQPEDRSSPWLYKPLLKAAMRGVVPSEVLKRETKGEASVDAANGLRE
                     NRARIAELWHDSRLARLGLVDADRLLATTLQPSSPELRYAGLDSTLACEIWLRTV"
     aSDomain        11919..12167
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_S1361_RS32745_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="6.40E-25"
                     /identifier="RREFam002.1"
                     /label="S1361_RS32745"
                     /locus_tag="S1361_RS32745"
                     /protein_end="83"
                     /protein_start="0"
                     /score="78.0"
                     /tool="antismash"
                     /translation="MRLRADVSLVETDYGKVLLDGRTGRYWELNPTGSLALDELTSGGD
                     IDSVTTRLTDEFEVGAERARSDAEALVAALVEAGLVDR"
     aSDomain        11919..12167
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_S1361_RS32745_Lasso_Fused_RRE.1"
                     /evalue="1.40E-08"
                     /identifier="RREFam003.1"
                     /label="S1361_RS32745"
                     /locus_tag="S1361_RS32745"
                     /protein_end="83"
                     /protein_start="0"
                     /score="25.7"
                     /tool="antismash"
                     /translation="MRLRADVSLVETDYGKVLLDGRTGRYWELNPTGSLALDELTSGGD
                     IDSVTTRLTDEFEVGAERARSDAEALVAALVEAGLVDR"
     gene            11919..12170
                     /locus_tag="S1361_RS32745"
                     /old_locus_tag="S1361_32710"
     CDS             11919..12170
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942881.1"
                     /locus_tag="S1361_RS32745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32710"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_208035481.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.8e-22,
                     bitscore: 78.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 3.9e-06,
                     bitscore: 25.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.3e-13, bitscore: 49.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLRADVSLVETDYGKVLLDGRTGRYWELNPTGSLALDELTSGGD
                     IDSVTTRLTDEFEVGAERARSDAEALVAALVEAGLVDR"
     gene            12167..12625
                     /locus_tag="S1361_RS32750"
                     /old_locus_tag="S1361_32715"
     CDS             12167..12625
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655082.1"
                     /locus_tag="S1361_RS32750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32715"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_208035482.1"
                     /sec_met_domain="PF13471 (E-value: 2.1e-28, bitscore: 97.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFQTVLRPPSAVPWRARLAARLAVGTAKPLTRLSPERIRRLLTA
                     LARGAQPARFEQVQAARDAVTTVSLLCAGREGCLQRSIATALLCRARGVWPTWCVGIRT
                     APPFAAHAWVESDGRMVGEGVPVGYFRVLFSVAPHDAKEGPDGRYGCG"
     gene            12603..14357
                     /locus_tag="S1361_RS32755"
                     /old_locus_tag="S1361_32720"
     CDS             12603..14357
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009303065.1"
                     /locus_tag="S1361_RS32755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32720"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_243769386.1"
                     /transl_table=11
                     /translation="MAGTAAGESVGYRDLFALLLERRTTVAWALALTVVGTVLGLLQPL
                     LTMRLIDRVGSGEPLAGPALLLAGLFAAQACIEGLGQFLLDVAGEGVVLRLRKTLANRL
                     LLARIGDFDRHRTGDLLSRVGTDTTVLRDMVAGSFVQLVTVALTAVGTGGLMLWLDPVM
                     FGIVIATIAAATVVVAGVMTGIRGTTEQSLTDVGTMTADLERALGNIRTVRACRAELRE
                     ARRIGAAAEAAFTSGVRSARLGSLVGPVMEVAVNGSFLLVLLIGAVRVSNGDMTISALV
                     AFLLYATYLVMPLAGLFSAVALIQRGLGSLKRIQEALRLPVESTSDPVEAPTRGPGPLL
                     ELVDVSFSYGDRQVLSGVSLRIPEYGYLAMVGRSGAGKTTVTSLIERFYDPDDGAVLFR
                     GTDLRKLEHRGYRRHVALVEQHTPLLYGSLRHNLTYAAPDASEDAIRDVLDTVGLDALL
                     RRLPDGLDSEVGERGLRLSGGERQRVAIARALLAEPDLLVLDEPTSHLDTVSEAEIAEA
                     LLRVSERCSLLVIAHRLSTVRSARRIVVMDGGRVSSIGTHEELLARDRTYQQLVESHLL
                     QSEKSAHA"
     misc_feature    12726..12728
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14350..14637
                     /locus_tag="S1361_RS32760"
     CDS             14350..14637
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="S1361_RS32760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_279577636.1"
                     /transl_table=11
                     /translation="MREVSGHEPHWKAALQRLDRLTPRESEVFSMMAEGLSNESMANRL
                     HLTERTVRAHLSAIAEKLELHSRLSLCLASYVSRNTVANDNVCRCGRRAE"
     misc_feature    14691..14707
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.98"
                     /tool="antismash"
     gene            14706..14900
                     /locus_tag="S1361_RS32765"
                     /old_locus_tag="S1361_32725"
     CDS             14706..14900
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038155.1"
                     /locus_tag="S1361_RS32765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32725"
                     /product="FDLD family class I lanthipeptide"
                     /protein_id="WP_069777648.1"
                     /transl_table=11
                     /translation="MSGNAFDLDVRVTSPSTAGLDRAPASISSLLTRAVCTRVTCKANC
                     TYVCTTVCTSGICPKEHSH"
     CDS_motif       14706..14774
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSGNAFDLDVRVTSPSTAGLDRA"
                     /locus_tag="S1361_RS32765_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       14775..14900
                     /prepeptide="core"
                     /locus_tag="S1361_RS32765_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-0.80"
                     /molecular_weight="4126.8"
                     /monoisotopic_mass="4124.1"
                     /core_sequence="PASISSLLTRAVCTRVTCKANCTYVCTTVCTSGICPKEHSH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSGNAFDLDVRVTSPSTAGLDRA"
                     /leader_location="[14705:14774](+)"
                     /alternative_weights="4144.8"
                     /alternative_weights="4162.8"
                     /alternative_weights="4180.9"
                     /alternative_weights="4198.9"
                     /alternative_weights="4216.9"
                     /alternative_weights="4234.9"
     misc_feature    14916..14934
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.57"
                     /tool="antismash"
     gene            15018..16355
                     /locus_tag="S1361_RS32770"
                     /old_locus_tag="S1361_32730"
     CDS             15018..16355
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980834.1"
                     /locus_tag="S1361_RS32770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32730"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_208035484.1"
                     /sec_met_domain="LANC_like (E-value: 2.6e-41, bitscore:
                     140.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRENRETAGWPARGEEDTLIERAHRAVRLVAERTSTTGQVTELAL
                     TAAEQSAHPVGWYPPSLSHGQAGTALLHLYTARAGLGDRDTAFEHMREAVLGTRVVPLE
                     VPGIFGGTSGLALALADCAHDEPRFLPSLRRVHEQLAAQVLDTDYLAVERAVTDADYDW
                     ISGAAGVLAYLVSIENPSPAVREAVGRLLDYLVWLSEPAQTRNTPHRWLLVPDVYPPVG
                     NDHDRYPHGYLNLGFSHGVPGVAAALAAAAASGHRHPGLDTAVTTFTAWILAHQAADEF
                     GPLWHDGVAVDVDGNEQPRLHGHDQIAWCYGTAGVASALLDISRSTGDNGLLTTAVTAF
                     EAVLRRAAQAGPLSPTLCHGQAGLLMMCRAFAPFSGLARERIPVLLDRLLEHADEARPA
                     VFADHQLPGHLVDDPGLLCGAAGVALAILAALNDDRPAWFRACFAR"
     gene            16361..19420
                     /locus_tag="S1361_RS32775"
                     /old_locus_tag="S1361_32735"
     CDS             16361..19420
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980835.1"
                     /locus_tag="S1361_RS32775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32735"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_208035485.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.2e-152,
                     bitscore: 506.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.1e-11,
                     bitscore: 44.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.5e-37, bitscore:
                     128.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRYVPADFYLLRSPALPAETFRAFMSDPDHTSGALLRLADDPEV
                     RRAIFVASEGLAEGLTQLERMSPKSLARVHSRLWRYVTRMSTRPTPFGAFSGVAAGTFS
                     GRTTARLETPVISSTRVRADMAWILACIKRLEDDQETWRSLRIVRNATAHVSGDRVVLP
                     HADVYGNSDRTSVRVRATPAVHTVLDAAATPVTYPELIDALTGAFPEATGPQKENLLQR
                     LWDLNFLTSDLRPPQTTAQPEQYLLDGLAGIPQAAEVAERLREVVELVRHADAPVSLAR
                     LRVAQEKLVPGYTGQTYQLDSAIGLRSDELNRSVGEAAADTVDVLMRLSAATGTTNAHL
                     RRYREEFLERYGHGVRVPVLELLGPDQGLDAPESYTEPTRKAGRLDSATDSEDTSSYDR
                     AVVEFAHQAWREGMLEAELTDAWLDRLAPEATVGPLLPAVDLYLQIEATDRQAVDRGEW
                     RAVLRADCLAHGGRTFGRFFDLLGDRLADQLRDLARWEQKLQPHVAYAEVAYLPTYGRA
                     GNVAAHPDLGMYEIPVNTSPSVPADRVLPLDDILVGADDRRFHLWSRRLEREIVVTQHH
                     MLSPLAAPNVARFLLEASHDGYVLPGGFHWGPVSNATFLPRVTRGKVVLRPAEWRLDGH
                     GLEDLAAWRERWRVPRYVYLVDLDNRLLLDLDHPRCIGELREEIGRAAGGTVLLHEMLP
                     DFEHHWLTDDLGRRYTEEIVVPVMAARAETIARHPAGAPVEIPSRRYPPGSEWSYVKLY
                     AAFERHDEIIAGPLRELIAELRAEDAVDRWFYIRYADPRPHLRIRVRSERPSVLGRLAA
                     WGRSLVDAGLAQDVTMDSYCPETMRYGGPDTFESIERLFEANSDTTARLIAARPDLAQL
                     VDEHLAVAAVDTLHRHWGVPLAERMDLLPGHRDDNATRDEFRKVRAYLCELLLPWDRST
                     HEEGRAHRMGIVAALAPQEPAVRAASAAVREAAERGRLAVPPAHLLGSLAHMQINRLLP
                     VDLAREERCYGLLRHTLRALRGRLAAEEAR"
     misc_feature    16469..16471
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        16802..17068
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_S1361_RS32775_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="4.20E-14"
                     /identifier="RREFam001.1"
                     /label="S1361_RS32775"
                     /locus_tag="S1361_RS32775"
                     /protein_end="236"
                     /protein_start="147"
                     /score="44.0"
                     /tool="antismash"
                     /translation="VRNATAHVSGDRVVLPHADVYGNSDRTSVRVRATPAVHTVLDAAA
                     TPVTYPELIDALTGAFPEATGPQKENLLQRLWDLNFLTSDLRPP"
     misc_feature    17663..17665
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19417..21201
                     /locus_tag="S1361_RS32780"
                     /old_locus_tag="S1361_32740"
     CDS             19417..21201
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980836.1"
                     /locus_tag="S1361_RS32780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32740"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_208035486.1"
                     /transl_table=11
                     /translation="MIWLRVLRLFWKMSARKVTAFAVASVLSAAIPGVQVGLTASAVQS
                     VAQAANGNEGAGRQALQVGVVLLLIAVAGHLLDVWGQYLDSLLRLELTTKIGEQVMVKG
                     TRLDLEQYENAESYDKLQRAFQESNGGRIYQLFSEMLTVTRELVTVVSVGAVLFTWSPW
                     VALFILVSPVPSVAAHMIYTNKAYAIEYARAADRRRTYYYQYLTTTDHSFKEVRLFQLG
                     PYLVERYRTLVHEFFRVDRQLARRQSGIVGLLGLLSVIASSGALLWAIGSAADGGQVGR
                     LAGYLQSMGAIQVSAHGLLLGIASLYKDTLFLGNLFAFLDLPERRITGGNRPFPAKLRK
                     GIEFRDVSFVYPGTDRLVLDGVDLLLPAGECVALVGQNGAGKTSIVKLLTRLYEPTGGR
                     ILIDDVPIEEYDVDDLQRHIGVIFQDFIRYEMSVRDNIGFGRIEAMDDDERIQAAAVAG
                     GVDTVVSDLPDRYDTMLGRHFEEGRQLSGGQWQKVALSRAFMRRAPVVVLDEPTSAIDA
                     EAESEIFGRLRDIARDATSLIIAHRFATVRIADRIVVLDGGRVVEEGTHEELLSADGTY
                     AHLFNLQAAGYLAEPASQ"
     gene            21239..22189
                     /locus_tag="S1361_RS32785"
                     /old_locus_tag="S1361_32745"
     CDS             21239..22189
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547824.1"
                     /locus_tag="S1361_RS32785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32745"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_243769387.1"
                     /transl_table=11
                     /translation="MPTAPSEAVPFAELVRSEDMPRLWQGQSVTIETHQMFAYLAGMGF
                     RIPFGTAVTLMPLRHPMEAAAHARSLARLTGRRVTLGLGPGSPDFVVSLHGKPYDSPKA
                     ACADYLRQVRGFLTEQRHKVPEAVRQASDLPDLGHPGVDIGLGVLRPTLARLAGETADV
                     AITWMTPPGYLARDVVPALRRGARAASRPVPRLVTVVHVAVDRHGRDPRQLAYAAARTH
                     LGAPHYTDMLRRAGLRVHPSQPYLNACALVDSGTFAYGTPREVAGALAEYARVGVDELV
                     LNCAGVGLVHGWNAALEDLAELSAEMRAVRSGVIA"
     gene            22235..23485
                     /locus_tag="S1361_RS32790"
                     /old_locus_tag="S1361_32750"
     CDS             22235..23485
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574920.1"
                     /locus_tag="S1361_RS32790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32750"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_208035488.1"
                     /transl_table=11
                     /translation="MTEEVQRWLKENALPLKGLHPEASNPGYGDLEPLRKVLRDVRVLG
                     MGEATHGTAEFFRLKHLLLRFLVEEMGFTALAMEASASAAQAVDDYVLHGTGDAVDAVA
                     GLGFWTWRTREMLDVVEWMRDHNRTVPQDRAVRFVGIDPQRCGPSLSALAAVLRTLAPE
                     RADITDGPLGTLAEARTGSLVDQRPQLLAEARDLERFLEEEHPRLAAHIGDTAVDQALR
                     HARLIVAAADVASRPPRGEGEETGALAARDRHMAQAVVSLEEGTAGKVAVWAHNGHVCT
                     DSYARDIPAMGRHLRDHYGERYYALGLLFGQGAFRARPGNSATRPPRKHTISAAGPRSV
                     EAQLASVTSEDHLIDLRAGRTEPVVAEWLESPQFMRSFGAGVPRVTYRFSMTQTVLMRE
                     YDGLAYVARSTPSVLLS"
     misc_feature    22421..22423
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            24387..26438
                     /gene="fusA"
                     /locus_tag="S1361_RS32795"
                     /old_locus_tag="S1361_32755"
     CDS             24387..26438
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fusA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521675.1"
                     /locus_tag="S1361_RS32795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32755"
                     /product="elongation factor G"
                     /protein_id="WP_208035489.1"
                     /transl_table=11
                     /translation="MRTHIDTLAAVRNLGILAHVDAGKTTVTERILYATGTTHKRGEVH
                     DGTTVTDFDPQERDRGITIFAAAVSCAWNGHRINLIDTPGHVDFADEVERSLRVLDGAV
                     AVFDAVAGVEPQSESVWRQADRHGVPRIAFVNKLDRAGADLDRAVGSLRDRLHPAPLVV
                     QLPIGAEDGFTGVVDLVRMRSLVWGDDEGTAMEGPVPEELREEAVRRRRALEEAVAERH
                     PAALEEFCDRETLFAATLTAALRDLTRTGDGVVVLCGSAYRNRGIEPLLDAVVAYLPSP
                     LDVPAVRGAGEDAGQRRAADPGAPFAGLVFKVNASATGRLAYVRVYSGTVEKGDAVWDP
                     GSGRTERVARILRVMADRHVQLDRAVAGDIVALAGVKSARVGATLCDPGAPVQLEAPVA
                     AEPVVSVAVEARRSTDTGRLAAALARLAEEDPSLVVRTDTETGQTVLSGMGELHLEVAV
                     EKIRRDGGPEVTVGRPRVAYRETVVGGVSGFVFRHVKQDGGAGQFAHVVLDVEPLGPEL
                     GVTGFEFRSAVVGGRVPQEYVRAVEAGCRDALTGGPLGGHPVTGLRVTLTDGSTHVRDS
                     SDTAFRTAGRLGLREALRACTTALLEPVAEVAVTVPEDAVGGVLGDLAARRGRVGGSRS
                     RGGAAVLTATVPLAELFGYATRLRSRTHGRGTFTTRPAGYAPAPPPVR"
     gene            26639..26869
                     /locus_tag="S1361_RS32800"
                     /old_locus_tag="S1361_32760"
     CDS             26639..26869
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="S1361_RS32800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="S1361_32760"
                     /product="hypothetical protein"
                     /protein_id="WP_208035490.1"
                     /transl_table=11
                     /translation="MVRLLGLGLAGVTMNPATVTRVQRTGNAGPLVNTVHSSFIALGLI
                     TELRDGGAAGTAVRRGTAVRRRERSPRHREW"
     gene            27020..28336
                     /locus_tag="S1361_RS32805"
                     /old_locus_tag="S1361_32765"
     CDS             27020..28336
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676083.1"
                     /locus_tag="S1361_RS32805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32765"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_208035491.1"
                     /transl_table=11
                     /translation="MRSIRAAAVGAVTLSLALAATACGGGSSTGGASGDSPKTLTYWAS
                     NQGASVAVDKKVLQPELDKFEKQTGIKVKLEVVPWSDLLNRILTATTSGQGPDVLNIGN
                     TWSASLQATGALLPWDEQNFAKIGGRDRFVESALGSTGVQGKDPAAVPLYSMAYALYYN
                     KKIFADAGIGKPPATWDELIADGKKIKARGKSVLGAEGANLSENIHHVFVFAKQHGADF
                     FTADGKPDFTAPKVVEAVKSYVDLMAKDKVVPAGDAEYAQNQSVSDFAKGRQAMLLWQS
                     AAANLKSQGMSEDAYGIAPVPVRSGTPGQGTQVNSMVAGINIAVFKNTHNLDGAAKFVK
                     FMTSDAEQKILNTAYSTVPPVRSAQDDPAFGAPDTAVLKNTLATSAAALPQVPSESQFE
                     TTVGTAVKELFADAAAGRAVTTDSVRAKLEKAQQQMPAA"
     gene            28342..29328
                     /locus_tag="S1361_RS32810"
                     /old_locus_tag="S1361_32770"
     CDS             28342..29328
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676084.1"
                     /locus_tag="S1361_RS32810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_32770"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_208036872.1"
                     /transl_table=11
                     /translation="MTTTALKEPVRETSPGAARAPRRRAGRIRRLSLPYLLLLPALLLE
                     LLVHLVPMAIGIVMSFKELTQFYIRDWSTAPWSGLDNYRVSVDFDAPVGKALLQSFGVT
                     VGFTLLSVGLCWLIGTAAAVFMQDAFRGRGLLRALFLVPYALPVYAAVITWVFMFQHDN
                     GLVNHVLHDQLHLTGEPSFWLIGDNSFYALLTVSVWKGWPFAFLIVTAGLQNIPRELYE
                     AAALDGAGTWQQIRRITLPSLRAVNQVLVLVLFLWTFNDFNTPYVLFGKAAPEAADLIS
                     VHIYQSSFVTWNFGTGSAMSVLLLLFLLVVTGGYLLLTSRGRRTADA"
     misc_feature    complement(29389..29398)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
ORIGIN
        1 ggcacatcgc cggccctgac gagcccgtcg acgaactggc cgcgcacgcc gccgccaagg
       61 ccctcgccgc ggccggcctc accccgggcg acatcgacct cgtcctcgtc gccacctcaa
      121 cggcgatcga ccgctccccg aacaccgccg cccgggtcgc ggcccggctc ggcattccgc
      181 agcccgccgc catggacgtc aacgtggtgt gcgccggctt cacccatgcg ctggccaccg
      241 ccgaccacac gctccgggcc ggggcggcca cccgcgccct ggtcgtcggc gccgacaaga
      301 tgtccgacgt caccgactgg accgaccgct cgacctgcgt cctcgtcggc gacggcgccg
      361 gggcagccgt cctcacggcg tgcccgccgg gggaggagcc gggggtcggt ccggtgctgt
      421 gggggtcggt gccggagatg gggcacgccg tgcggatcga ggggacgccg ccgcggttcg
      481 cgcaggaagg gcagagcgtc taccgctggg tcaccaccca gctgccggcc atcgcccgga
      541 aggcctgcga gaaggcgggc gtcgcgcccg aggacctcgc gggggtcgtc ctgcaccagg
      601 ccaacctgcg gatcatcgag ccgctggccg agaagctcgg cgccgtcaac gcggtgatcg
      661 cccgcgatgt caccgaatcc ggcaacacct cggccgccag catcccgctc gcgttctcca
      721 agctggtcga gcgaggagcg ctcagcaccg gcgacccggt gctgctgttc ggcttcggcg
      781 gcaacctgtc gtacgcggga caggtcgtcc gctgcccctg agcccgggcc ggccgtccac
      841 aacccgtctc tcacgcaggg tacgcagggt cttgccgtcc gtatcccgtc gtcatcgccc
      901 cgggtcccca gccgccccgc agacggatac gcaggtgaaa cgcactccga aaccttggta
      961 ttgttgtcca tgtcgccgcg gggaacacac cccgccaggc ggcagacacc tggtccgggt
     1021 ggcggaatgg cagacgcgct agcttgaggt gctagtgccc tttatcgggc gtgggggttc
     1081 aagtcccccc tcggacacag acaagggacg ttcacgagat cgccccgaag cgttcacgaa
     1141 ttaccggtcg agtcatgtta ctcgccggta tttcgtcgtt tctgggcctt cgggcctcgt
     1201 gatcggctcg gtgaggggtt ggtgcggtgg cggtccgagt gctgcgtctc tcatctgcgg
     1261 aaacaggaca tgcctgtgcg acggctggtg gccgtggcgc aggcatgtgg ggttttcagg
     1321 aggcagagcg cggcggaggt gtgtcactcg cgtggcggag gctcgacctg ctcggtcgga
     1381 agcggtcgcg cctggggcgg gtcgaagggc tcaccaggtg gggttgcggc gctctgcgtg
     1441 ccggctttgc ggggctggat gccctggtcg cggaggaacc gtcggatggc tctgaggttc
     1501 gccacgaaga tgatgacggc attgagcagg gtctgtgcga cgcgtccgtg cggcaggcgg
     1561 agctggggat tgtcgatgct gtcgagggcg gacttcttga ggttgccgtt gccgccctcg
     1621 ttctgacttc gcagtccgga ccaggcttcc tgccacaggg gggtgaacag ggggtatttc
     1681 tgccgccact cggccaacac ggtgcccggg acggtgatgc tcttccccct gcagatgtcg
     1741 gggtagacgg gggtatcccg cttgggcctg gggatggtgg acagggctgc tggggtacgg
     1801 gcagtggggg cgtcgaggtc gacgacggtg gacgggcgtg gctggggccg gcggtagcag
     1861 gtgaccgtgg cgtgggaccc gagggcgggg cactgtctac gctggtcccc tgcgggcccg
     1921 tactccttga tcttggtctg gtagtccttc cgggactgga tcaggttgag tgcgtgggcg
     1981 cggtcctcgt ccgtgcggct gtcgatgtat gtggcgcccg cagtgatgag cggggccggc
     2041 atcagcgggc agtagaactc gccgccgacc agctgcatgc cgcggaactc tccctgccgg
     2101 tcgaccttgt cgtcgttgta gtgcttcacc gcgtgggaga tctgcgtctt cacgtcaccg
     2161 agcgtggtcg tcccgctcta ctctgaccag cacatccctc agtacggagg gtgcttgtat
     2221 cgacacggaa ggtttcgtgt gcggggtgtc ggtcgtgacg cgggaaaggg ggcagtcgtg
     2281 tgcgaggcgg cggtggaggc gcagggggcc tacgacgagg gggagttgag cggtgacctg
     2341 atgcgtgcag tgggcaagcc cgcgctcggc agcgccctga cggctcccgc ggagggccgc
     2401 tgtgcggccg tagggagcga gcttgctgta gctgccgatc gcgtagcggc cgatgaggtc
     2461 accgagcagg aagagatcag ccgcaaccgg tgccagccgt gattgacctg aaacggcgtt
     2521 tgttgttcca gcgaggtttt ggttcgaggt tcaggtgtcg cgccagttcg gggtggactc
     2581 actgatgact cgtcggcgta tgaggtcgat caccgcggcg tggatcacgg cttcggagcg
     2641 gcgggaagtg ggtttcgtag tcgcgtgcga gacggcggtg gtgcataggc cagtcgaagg
     2701 tccgctcgac cacccgtcgt ggggggatca ccttaaaccc ttatccgctg gagccgcgtt
     2761 ggacgatttc tacgtcgatt ccgaggcggg cgccgcggtc gatgggggcg ccgcgccggg
     2821 cgatcttcgg gacgatgccg cggacccaca ggagtcggcg gtacttgcgg aagtcgtagc
     2881 ctcggtcggc gtacagacgc ttcggcttgt ggcgggggcg gccacgccgg ccccggatgc
     2941 gcggaatggc ctccaggagc gggacgagct gggtgacgtc gtgccggttg ccgccggtca
     3001 gtgagacggc aagcggggtc ccgtggcggt cgacgatcac atggtgcttg ccgctgggac
     3061 tgaccccggc gtacagccga ctcgtctgcc gccacctgcg gctttgcctc tgaaagggac
     3121 tctgacctgc agcggagtgc cctctccgct ctttcaggag cttgccgcgt caggcggcgg
     3181 aaagtccctc gttagtccct cggacagcgc tgaaagcccc tggaacgcag attcgggcaa
     3241 ctcttctggc ctgtggcaga tcgtagtccc ggtggatcgc cgtacgtcgt gccgacgacc
     3301 acatcaacgt ccgttgccac cctcgtccgc gaagacggca tccgtgccca gaccgaatgc
     3361 cgagagaccg aaaccgactt cggcccccag atcctcaacg gcggcgacca caccgccgcc
     3421 cagcgcccca ctagcgccga acgttccaag gccgagcgat ccggccgtat cgagacaccc
     3481 cgcgagacgc tgcgggagag cgtccgccac gccctggccg gagccgccag cgaggaagag
     3541 ttcttgtacc gcctcgctgt cgccgacctt gcccgtgaac gagcaccgca tccggcccgc
     3601 gcccgacgcc aggcagcacc agtcaccgaa cgggcggcat cgatcctcga cgggaacgac
     3661 gacgaggact ccgctcggcc ccgactcggc gccgggctct agcagctttc gcccgaggcc
     3721 gcggcgctca cccctacgct cgaggacgag atgcggggcg ccgcgatgca cacgctgggg
     3781 tacgcggacg atgtacttgg cccagcggcg ccgagagttg accggtcggc acggctgcat
     3841 gacctcggcg tggttgcgcg ctcgctgctg acagtcgtcg agatgaccgc tgagtatgaa
     3901 gcgaggcagg cgctctatgg cgcggcggcc cgtcagcaag tcattacagg gaggctgcgc
     3961 agtccccgtt tgtgaaacgt cggccaccac tccaactcgt taagccccac cgccagttca
     4021 agctcggaga accgtttcat aagggaccat acggcgattt ccgcctccat ccgcgcgagc
     4081 ggggcgccaa tgcagtagtg cactccgtag ccgaacgcca agtgagttgg tgtacgggtc
     4141 gggtcgaaca cctcgggaga cgggaactcc cgcccgtccc ggttcgccga agcgatggag
     4201 acccacactc gactgccagc ggggatgaga gcgttaccga tgctgacgtc ttcgagggcg
     4261 aagcggcgta ccgccagtgc gaaagggggg ttccagcgca gcgtctcctc gaccaccgac
     4321 cgtatcggga cggcgccacc tcgcaccgcc gtcagcagtc gggggtgcag cagcagactc
     4381 aatgctgtgt tgccgatgag atgcacggcg ttgtcgtagc cggcgaacag agtgaggaac
     4441 gccagggaga cgagttcagg ctcggtgagt acgtcgcggt cgtcgcgggc ttggacgagg
     4501 gcagacagaa ggtcctcggt cggactgttt cgtttttcct cgataacact tttgagaaat
     4561 tggtgcatct gcctcatcgc agtgcgtgac tccgttgccg cgcctggcgc tggtgagaag
     4621 agtgtgtcgg tccaggcccg aaagtcgagc ctcgctgtct ccgggatgcc gagcagttca
     4681 cagatgacgc tcatcggcag tgggacggcc agggcgtgga cgaggtccac gcgagggccg
     4741 gtcatcgtgg tgaggagttc gtcggtcagc ttctggatgc gcatgcgcag gccctcgacg
     4801 cgacgaggag tgaatgcttt ggcgacgagc cggcgcaggc gagtgtggtc gggcggatcc
     4861 atgttgagca ggtgagtatc gagctcaggg ggcatggagg atctgtactc gccgctggtc
     4921 ttggcgtttg ccttgttcag ggagagccgg gggtctgcca gagccgcgcg ggcctcggcg
     4981 taccgggtga tcagccacat gggttcgccg tcgggagtgg cggtgcggtg gaccggggcg
     5041 gcttcacgga gccgggcata ggtgccatgt gggtcagcga cgagtgcttc actgagcagc
     5101 gacgagacgc tgccggtctg ttcggtgttg ctcatgcgtc cgttttcgcc gactggagcc
     5161 gctcgagaac ggcggggatg acgggggagg tgctgaaggc gtcggcgacc agggtcagac
     5221 gagcaccttc cttgctgagg tcgccgttgg cggcgtcgtc gaagtctgtg ccatgtcccc
     5281 ctgacgcctc gtggccggtg gaccgagcct gaagggctgc tgcgatctgc gcggcttctg
     5341 caacggcatc cgcctcgtca ccggggatgt tctggttcgc cgctacttct cgtgtcatgc
     5401 ggctgatctc cgggtcatgg tggggacgaa gtctcatttc gccgtcgagt atctcgatca
     5461 cctggcgacc gaggaagaac cggaggtcgc gagccagttc cctgcgggag gtcggcgggg
     5521 tgacgaggac gacttcgggg aaggcacggg tgatcgcctg ccaaaggggg tagcggcggt
     5581 ggaaggtgcg gtagtcggac atccatgcca tgacccggcc gaggccgacc ccccaggcgg
     5641 gcatggtgaa ccctatggcg aagagtgccg ccgagacgct ggcgaacatg ggggccacaa
     5701 cggagttgac gaaaccgagt ggtgagatgc cgagcttgtc ccagatgagg gagatgacct
     5761 tgggcaggca gtagcccaag ccggcgactg ctcccacggt gacgatgcgc aggccgcgcc
     5821 gcagccaagg ctggccgacg atcttggagt agcgccagca gagccggatc agcccgatca
     5881 tgctgactgt gtacagggtc tggtggacga ggaggaactc ccagatgtat gcggtcttgg
     5941 catagtgaac gtcgaagtca agggcatgcg acgtatcggt ggcgtccccc aggaagaaca
     6001 gcacccagtt cgtggtgacc gtggcgaggg cgtatccgag gatcagccgg tgacggagcc
     6061 ggaccttcga ctgcgcagac gaccagctga cgaggagggc caggaacgag gtgaggcaga
     6121 cctccacggt cgtgtagatg atcagcgaac tgatgttggg cgtgccgatc agagcatcga
     6181 cacgtacgta caccggggga gcggcgaagc cgaacggtgc ggcgaacatt gcgatcgcca
     6241 gacacagccg ctgcagttcc ttgttgcgcc agtcgcgggc gaggtctctc agcttgaagg
     6301 cgaacgcgct ccaagtgatc aaggagagcg ttccgtagac gacattgaat aacactcggc
     6361 tatgtccttg gtgtggaact gcgccccagg gagcgctcga ggtggctgac gaggttgacc
     6421 acgtcttccg aaagacttgg cgtcggccgg ggagcggcgt tggcggcctg cagggggatc
     6481 agcgaggcaa caagctcggc agccctctcc tcgctccggt cgtagcaggt gcgcccgagg
     6541 acggtgcgca ctagcgccgg gtcgatgttc ggcagaagga gtcgggagac ctcttcctcc
     6601 tctgccgggg tggactcgtg ctcgcagagc atgtggccga tctcgtggag gacgatgtgg
     6661 ccttggtgcg cttttctggc ctcctcctgg tagatgacgt agtccacgtc ggatgttgcg
     6721 acccacatgc cgcacaggcc tcggtcggcg gggagcggca tcggtacgag cgagatggca
     6781 cgtccgcggc gctcctctat ctggtcgacg agggcattga tgttgaacgg ctcggggatg
     6841 tcgagttgcc ggaccagatc ggcgcagtag cgacgcagtt ccctgtcatt catccccgct
     6901 ccccccgggt cggcccactg ccactggaca aagaccactt tcgtgctccc cccctcacca
     6961 ccgcggcgcc tgtctcgctc ggcagcggcg gaagtccgca tggaccgccg gacccaaccc
     7021 agttgcctgc agtggagcat cttcgtatac cgccctacca gcagctcaca tccgttgccg
     7081 cttgcttgcc cgctgcaggt gctggatcac cgggacgagg gcagcaagcg cctcctcgtc
     7141 caggtcggcg actgcccgaa gagcgatctg gcgggggccg atgccctggg acttcagcgt
     7201 ctccacgagg ttgagatctg cggagacctg agacgctact tcgtcgttga cgaagtagcc
     7261 gacgggtacg ccgaagaagc tggcgagcgc atcgagttgc tcaggactcg gcgaagtcca
     7321 ggtgccgtgt cgtagctcct cgacttgtgc tgctgtgatc ttgaccccgt gcgcggtgat
     7381 tgtctcggca acctcgtgcg aggtgtacgt ctcacgccct ctggggtgca tgaccgcgaa
     7441 aaggcggttc agtcgcgccg agagatccgg gacggcggac ggcggctgcg caggcctcgg
     7501 cgggttctcg gcgtccgcct cccggggtga gggcaccgca gcttcgcgct ccgccggcga
     7561 agtggctgaa ccatcgacct ccggcctccc tgacgtctgc tgcagcgcgg ccaacatggg
     7621 cagcagtacg cggttgaggg cctcagcagc tggggcggtg aaaaacgcct cgcctccctc
     7681 gacaccgaag aatcccacca ggccgtgcag cagttcaaca ctcggtactt tgtcgccaga
     7741 gcacacctga cgtgcccaga aagaggaaac acccagctgt cgggaaatgc tgccagccag
     7801 gtctgacata ggctttccgg tgcgtgccaa gtatgcatca gcaaggatct tgatacgtgc
     7861 actgacccgg gctgccacgg tgtcggccgg agtgtggccg cctctgagta ggacggcgac
     7921 ggtgttttgg ggcagcgccg cctttgctgc cagctccccg atgtcgagca cttgcgatcg
     7981 attcatgccc cgttctttga gcagtgcctc gaggcgcgca agcgtcatcg gcaggggtga
     8041 ggcagagccc actgagacac tcccaggcta cggatggtta ggttggtctg tgcatggcac
     8101 cttacagcgc ccctggtggc aggctcaacg atcatttatc gccgaaaatg agattgttgt
     8161 gcatcggtcc gctcgtgccg gcaggacgtc acgaggcagt gcgtggctac tcgacatctg
     8221 tcatggcggg cgttgttggt gtagctctgc agatgcggca cgccgtcatt ccgtgttgcg
     8281 ggcgccgttg gtgcggcccg tgacctgccc cgcgaagtgc cggacagttg cggatggggc
     8341 gtgggtgagt ccgcaacgtc aggcaccacc tgcagcgcca cactgtctgg tctagagccc
     8401 aggtgggcaa gaccagcggg tgtcgcgcac tgcatgcttt caacgatcct ttagctgaaa
     8461 acgatcgttg acattgctta ttggacctag cacgatcctg ggctagtcga gccgtgtccg
     8521 atggacaact tcccgtgacg gacatggccg tgatccgttt gattttcaat cgttgaatcg
     8581 gaggcgcgta tatgcgtgcg ccaactgtgc ggacggcgct tcaactggct gacgacgact
     8641 tcaccaaaac ggatgtggcc gaattccatc gcttgatggc ggagattgtc gtggtgtgca
     8701 aggcgatcgg ggagctgtac acgcctgggg gcgaatggtc cccgatcgcc accggtctcc
     8761 ttgagtagtt tgaggaatcc atgcaggtca ccgcggatat ttcccgccag ctcaacagga
     8821 cgcgcagggg tatccgcaga attaccgaca gggcccgtac gcgcagggac gacggtcgtg
     8881 gcggccgctg cggccatacg tggtggccct aggaaggcgg ttcctcgcac ggctggcctg
     8941 cgagccccat gctggggcct gcctggtagt acttcgtccc tggcccggca tgtcccgtcg
     9001 ccgctgtcac agccagaatc tgtcaagtcg atgcccgaac gccacgccgg cagacctccg
     9061 gcggacgctt ggtgcggcaa cccttcgacg actcttcgag tctgcgccgc accggtgcac
     9121 tgaaggaaaa gcacaagggg gaaacgctct gatgacatcc gtaccacatc cgcccgcatc
     9181 cagtgtcgat ccagctggca ggaacattgg agccggcgcc gcaccaggtg ccgggtcggc
     9241 gctctacacc cggatagggc gcaagctcaa gcaggagatc gtgtcgggtg tctatgccca
     9301 gggcgcgtac ctgccttcgt cgggtgaact cggaaagtta tatggcgcga acaagaacac
     9361 cgtcctccgg gcgcttcgga tgctgcgcgc cgaagggctg atcgacttcg gccggggccg
     9421 tggcgcggtc gtggtgcact cggcgcgcaa agtgggcctc gcggagatat cggagcagct
     9481 ccgctacgtc gtgaaccttg ccgacgtctc cgggattccg agggccgccg tcgtggctgc
     9541 aatacaccga attccgccat cgcaaggccc gcgccccgct ggggccttgc ccgccgcggc
     9601 ggcccgacgt gggggagcag gccgcacggc gttcaggccg cacgggcgtg gtgccgcgtg
     9661 acgggcggca ccgccgcgac agtggcaagg aagctaatac ccagggtcac gataaagcca
     9721 gggaaaccat ctctcctggc cgaggatccc ttcgtgcgcg atgactcgga gcatgggcaa
     9781 aaggccaggc agcgccgtag ccccgagggt cggttgatgt actctccgtg gtgaccacgc
     9841 agagtacagg aattggtctt tcattgatcg ccgcattcac ctgcgcctag attcgctggc
     9901 gaccggaaga ccccacgggg caccgcgtct actccatacg gaagggaggt gaacagcatg
     9961 ggacggaaga tctacgaggc gccggcgatg ttcattgccg gtgacttccg actggacacc
    10021 ggattcctgc ggcgcggtcc gcatgagccc agggtccgtc tgccgctggg ttggtagcga
    10081 tctctggaga actatgtcga gccacggcga aagctggttt gtggtactgc ctgattgtga
    10141 ggccggcctc gccgtggcct cgcgtctcga agaacaacga agaaacaagg ccccaaagcg
    10201 ggtgctccat ccttccggcc ggcccctgct gatcggctcc tggggctccg cgttcgtcac
    10261 gacgacccgg cacggtctcc aggtcgcggt catcgggtcg agttccgcgg acgaggacgg
    10321 tatcgcgcag cgcctcgctc acgagcgtga catcgcgtcc gccgcccgca agctggcagc
    10381 cctgcgcggc gacttccaca tcgtcgtcgc ggggggcagc cggctgcggg tccgggggac
    10441 cgcgtccggg atgaggcggg tgttccacgc cgacacggca ggcgtgacag tggcgagcaa
    10501 tcgcgccgac gtcgtcgccg ggctggtcgg cgctcccctc gacgaggaac tgctcgccgt
    10561 ccgtctgctg gactcggtcc cccatccgct cggcgatgtg ccgttgtggc ggggtgttca
    10621 cgctgtgcca ccgggctttc agttggacac cggcccggac ggcgtttccc gcacgcggtg
    10681 gtggagtccc cctgagcccc ggctgggtct ggaggagggg gcggcactgc tacgccggga
    10741 actcgacttg gcggtccgtg tgcgcacggg ggcggcgacg acggtcagtt cggacctgtc
    10801 cggagggctg gactccaccg ctgtctgtgc cgtggccgcc gctgccggtg ccgcaccgtt
    10861 cgccctcacc atggcgagcc gtgatcctgg tgacgacgac gtccactggg cgaagctggc
    10921 tgcggccggc ctcaagcacg cggagcacct cgtgctcccc gtcgaccagg tcccgctgtt
    10981 ctacagtgga ctactggagg tcaccggacc ggtcgacgag ccgacgccga ccatcctcga
    11041 ccagccccgg caactcgctg gtcatgacga gatggcggtc cgcggttcag aactgcatct
    11101 cactgggatg ggcggcgatc acgtcctgtg ggggcacccg gcgcacgtac tccaacggct
    11161 ggccaccgag ccgttcggcg cactgcgtca ccttcgcgca taccgggcgc aaaacaggtg
    11221 gtcactgcgg gacgccctgt cggtgatcgg tgaccgcagg tcctatggcc agtggctggt
    11281 tgccagtgcc gaccggctca ccgctccccg ggcggcgccg cacagtgcgg acgtccttgc
    11341 ctgggacgtc ccaccccgga tgcccggttg ggcgacgccg gacgctgtcg ccgccgtacg
    11401 ccgccgaatg cggctggcgg cacagtcagc tatccccctg ggcgggaccc gggctcagca
    11461 caacgaactg aacatcctgc accacggcac acgcgtgacc cgcgtcctgc accaggtgtc
    11521 cgagcagggc ggtctgccga tggccagccc gttcttcgac gaccacgtga tcgaggccag
    11581 ctggtcggta cagccggagg accgctcctc accctggctg tacaagcccc ttctcaaggc
    11641 tgcgatgcgt ggcgtggtgc cctccgaggt gctcaagcgc gagaccaagg gtgaggcgtc
    11701 cgtcgacgcg gccaacggcc tgagggaaaa ccgggcccgg atcgcggagc tgtggcacga
    11761 ctcccgtctc gcccggctgg ggctggtcga cgcggacagg ctcctcgcga ccacgctgca
    11821 gccgtcctcg cccgaactcc gttacgcagg tctcgattcc acgctggcct gcgagatatg
    11881 gctgcgcacc gtctgagcgc cgtccgaagg gggaaacgat gcggctgaga gccgacgtgt
    11941 cactggtgga gaccgactac gggaaggttc tgctggacgg acgcaccggg aggtactggg
    12001 aactgaaccc gacgggcagt ttggcactgg acgaactgac ctcaggcggc gacatcgact
    12061 ccgtcaccac ccggctcacc gacgagttcg aggtcggtgc ggaacgagca cgctccgacg
    12121 ccgaggcgct cgtcgcggcc ctggtcgagg cggggctggt ggaccggtga gcttccagac
    12181 cgtcctgcgt cccccgtcag ccgtcccctg gcgtgcgcgg ttggccgcgc gcctggccgt
    12241 ggggacggcc aagccgctca cacgcctgtc accggagcgc atccgccgac tgctgaccgc
    12301 cctcgcacga ggggcacaac cagcccgctt cgagcaggta caggccgcgc gggacgcggt
    12361 caccaccgtc agcctgctgt gcgcgggacg cgaagggtgc ctgcagcggt cgatcgcgac
    12421 cgcgctgctg tgccgggccc gcggtgtctg gccgacgtgg tgcgtcggca tccgtacggc
    12481 cccgccgttc gccgcgcacg cctgggtgga gagcgacggc cgcatggtgg gggagggcgt
    12541 ccccgtgggc tacttccggg tgctgttcag cgtggcacca cacgatgcga aggagggtcc
    12601 cgatggccgg tacggctgcg ggtgaaagcg tcggctaccg cgacctgttc gcgctgctct
    12661 tggagcggcg gacgacggtc gcctgggcgc tcgctctgac ggtcgtcggc acggtgctcg
    12721 ggctgttaca gccgctgctc acgatgcggc tgatcgaccg ggtggggtcc ggcgagccgc
    12781 tggccggccc ggcactgctg ctcgccgggc tgttcgccgc tcaggcatgc atcgagggcc
    12841 tgggccagtt cctgctcgac gtggctggcg agggggtggt cctgcggctg cgcaagactc
    12901 tggcgaaccg gctgctgctc gcaagaattg gggacttcga ccgccaccgg accggtgacc
    12961 tgctttcccg cgtgggcacg gacacgaccg tgctgcgcga catggtggcg ggcagcttcg
    13021 tccaactcgt caccgtggcg ctcacggccg tcggtacggg tggactgatg ctgtggctcg
    13081 accccgtcat gttcggcatt gtcatcgcca cgatcgccgc agcaactgtc gtcgtcgccg
    13141 gtgtcatgac cgggatccgc gggaccaccg agcagtccct cacggacgtc ggcaccatga
    13201 cagccgatct cgaacgggcg ttgggcaaca tccgcaccgt gcgcgcctgc cgggcggaac
    13261 tccgcgaagc ccgacgcatc ggcgcggccg ccgaggccgc cttcacgagt ggggtgcgat
    13321 cggcccgttt gggttcactc gtgggaccgg tgatggaggt cgcggtcaac ggatcgttcc
    13381 tgctcgtgct gctcatcggc gcggtacgag tctcgaacgg cgacatgacg atcagcgcac
    13441 tcgtcgcctt cctgctctac gcgacctacc tggtgatgcc gctggccggc ctgttcagtg
    13501 ccgtcgccct catccagcgc ggcctcgggt cactgaaacg cattcaggaa gccctgagac
    13561 tgcccgtgga gtccacgtca gaccccgtcg aggcgcctac ccgagggcca ggcccactgc
    13621 tcgaactggt ggacgtctcc ttctcgtacg gggaccgcca ggtcctgagt ggggtgtcgc
    13681 tccggattcc ggagtacggc tacctcgcga tggtgggcag gtctggcgcg ggcaagacca
    13741 cggtcacctc cctcatcgag cgcttctacg acccggatga cggagcggtg ctcttccggg
    13801 gcaccgacct caggaagttg gaacaccgcg gctaccgacg gcatgtggcg ctggtggaac
    13861 agcacacacc gctgctctac ggttccctgc gccacaacct cacgtacgcc gcaccggacg
    13921 catccgagga cgcgatccgc gacgtgctcg acacggttgg cctcgacgca ctcctgcgac
    13981 gcctgccgga cgggctcgac agcgaggtgg gcgaacgagg gctgcgcctg tcgggcggcg
    14041 agcgccagcg cgtggccatc gcccgcgccc tgctcgccga gcccgacctg ctggtgctgg
    14101 acgagcccac ctcgcacctc gacaccgtca gcgaggcgga aatcgccgag gctctgctga
    14161 gggtctccga gcgctgctcc ctgttggtca tcgcccaccg gctgtcgacg gtccgctcgg
    14221 cgcgacggat cgttgtcatg gacggcgggc gggtcagttc catcggaaca catgaggaac
    14281 tgctcgccag agaccggacc tatcagcagc tggtcgaaag ccacctgctc cagtcggaga
    14341 aatccgcaca tgcgtgaggt cagtggacac gaaccccact ggaaggctgc cctgcagcga
    14401 ctggaccgcc tcactccacg ggagtcggag gttttttcca tgatggcgga aggtctgtcg
    14461 aacgagagta tggcgaaccg tcttcatttg actgaacgaa ccgtgcgcgc gcacctttcg
    14521 gcgatagccg agaagttgga actacactcc cgtttgagcc tctgcctggc gtcgtacgtt
    14581 tctcgcaata ctgtcgcgaa cgacaatgtc tgccggtgtg gccgacgagc agaataggaa
    14641 tcaagcagag gccgactctg cgtcattccg taatccgacg gaattgtcac gcgaaaggaa
    14701 atcacatgtc cggcaacgca ttcgatctgg acgtccgggt tacctcgccg tccaccgccg
    14761 gcctggacag ggcaccggca tccatctcct cgctcctcac ccgcgcggtc tgcacccggg
    14821 tgacctgcaa ggccaactgc acctacgtct gcacgaccgt gtgcacctcg ggcatctgcc
    14881 cgaaggagca ctcgcactga accggatgag cccgctctga tcgggctcac cttcgacaac
    14941 gggtgttgcc gtgggctcag cacggcaaca cccgtttcca ctgcgacagc cgaacggccg
    15001 cgacacgagg gatggacatg cgtgagaacc gggaaacagc cggctggccg gctcgaggcg
    15061 aggaggacac gctcatcgaa cgcgcacacc gcgcggtccg cctggtcgcc gaacggacct
    15121 cgaccaccgg ccaggtgacc gaactggctc tgaccgctgc ggaacagtcg gcgcacccag
    15181 tgggctggta cccgccgagc ctcagccacg gccaggccgg aacagccctg ttgcacctgt
    15241 acaccgcccg cgcgggactc ggcgaccggg acaccgcctt cgagcacatg cgggaagccg
    15301 tgctcggcac ccgcgtcgta ccactggagg ttcccgggat cttcggtggc accagcggac
    15361 tggccctggc actggccgac tgcgcccacg acgagccacg cttcctgccg agcctgcgcc
    15421 gcgtgcacga gcaactcgcc gcccaggtgc tcgacaccga ctacctggcc gtggaacgcg
    15481 cggtcaccga cgccgactat gactggatca gcggagcggc gggggtcctc gcctacctcg
    15541 tctccatcga gaaccccagc cccgccgtcc gggaggccgt gggccggctc ctcgactacc
    15601 tggtgtggct gagcgagcct gcgcagaccc ggaacacccc gcaccgctgg ctgctggtcc
    15661 ccgacgtcta cccacccgtc gggaacgacc acgacaggta tccgcacggg tacctgaacc
    15721 tcggcttctc gcacggcgtg cccggagtcg ccgcggcgct ggctgcggct gctgcgtccg
    15781 gccaccgaca cccgggactc gacacggccg tcaccacctt caccgcctgg atcctcgctc
    15841 atcaggccgc cgacgagttc ggtccgctgt ggcatgacgg cgtggcggtt gacgtggacg
    15901 gcaacgaaca gccccgcctg cacggccacg accagatcgc ctggtgctac ggcacggccg
    15961 gtgtcgcctc ggccctgctc gacatctcgc gcagcaccgg tgacaacggc ctactgacta
    16021 cggccgtcac cgcgttcgag gccgtgctgc ggcgagctgc gcaggccgga ccgctgtcgc
    16081 cgaccctgtg tcacggacag gccggcctgc tgatgatgtg ccgcgccttc gcacccttca
    16141 gcggcctcgc ccgcgaacgg atccccgtcc tgctcgaccg gctgctcgag catgccgacg
    16201 aggcacgacc ggcggtgttc gcggaccacc agctgcccgg acacctggtg gacgacccgg
    16261 gcctgctgtg cggagccgcc ggagtcgccc tcgcgatcct cgctgccctg aacgacgacc
    16321 gtccggcctg gttccgggcc tgcttcgcaa ggtgatgcgc atgtcccggt acgtacccgc
    16381 cgacttctac ctcctgcgct ctcccgcact gcccgcggag acgttccgcg cgttcatgag
    16441 cgaccctgat cacacgtccg gcgccctgtt acggctggct gacgaccccg aggtccggcg
    16501 ggcgatcttc gtcgccagcg agggcctggc ggagggcctc acacagctgg aacggatgtc
    16561 cccgaagagc ctggcgcgcg tccactcacg gctgtggcgc tatgtcaccc ggatgtcgac
    16621 ccgacccaca cccttcgggg cattctcggg cgtcgccgcc gggaccttct ccggacgcac
    16681 caccgcccgg ttggagaccc ccgtgatcag cagcacccgg gtgcgcgcgg acatggcatg
    16741 gatcctcgcc tgcatcaaac ggcttgagga cgaccaggag acctggcgga gcctcagaat
    16801 cgtccgcaac gcgacagccc atgtctccgg tgaccgggtg gtcctgccac atgccgacgt
    16861 ctacgggaac agcgaccgca cgtcggtgcg cgtccgggca acccccgccg tgcacaccgt
    16921 cctggacgcc gccgccaccc ccgttaccta ccccgagctc atcgacgcac taacgggcgc
    16981 cttccccgag gcgaccggtc cgcagaagga gaaccttctc cagcggctgt gggatctgaa
    17041 cttcctcacc agcgaccttc gcccgcccca gacgacagcc cagcccgagc agtacctgct
    17101 cgacgggctt gccgggatcc cgcaggcggc agaggtggcc gaacgactgc gcgaggtcgt
    17161 cgagctggtc cggcacgcag acgcccctgt ttcgctcgcc cggttgcgag tggcccagga
    17221 gaaactcgta ccgggttaca cgggtcagac gtaccaactg gactccgcca tcggcctgcg
    17281 gtccgacgag ctcaaccggt ccgtgggcga ggcggcggcc gacacggtgg acgtcctcat
    17341 gcgcctgagc gcggccaccg gcaccaccaa cgcacatctg aggcggtacc gggaggagtt
    17401 cctcgaacga tacggccacg gcgtgcgcgt gccggttctg gaactgctcg gcccggacca
    17461 ggggctggac gcacccgagt cctacacgga gccgacccgc aaggctggcc ggctcgacag
    17521 tgccaccgac tccgaggaca cctcctccta cgacagggcc gtcgtcgaat tcgcgcacca
    17581 ggcctggcgc gaggggatgc tggaagcgga actcaccgac gcctggctgg accgccttgc
    17641 ccccgaggcg accgtgggac cattacttcc cgcggtggac ctctacctgc agatcgaggc
    17701 caccgaccgg caggccgtcg accggggcga gtggcgggcc gtcctccgag ccgactgcct
    17761 cgcccacggc ggacgcacct tcgggcgctt cttcgacctg ctcggcgacc ggctggcgga
    17821 ccagctgcgc gacctcgccc ggtgggagca gaaacttcag ccgcacgtgg cgtacgccga
    17881 ggtggcctac ctccccacgt acggccgggc cgggaacgtc gccgcgcacc cggacctggg
    17941 gatgtacgag atacccgtca acaccagtcc ctccgtgccg gccgaccgcg tactgccgtt
    18001 ggacgacatc ctggtgggcg ccgacgaccg gcggttccac ctgtggtcgc ggcggctgga
    18061 gcgcgagatc gtcgtgacgc aacaccacat gctcagcccc ctcgccgccc cgaacgttgc
    18121 ccgcttcctg ctggaggcct cgcacgacgg gtacgtgctg cccggcggat tccattgggg
    18181 acctgtgtcg aacgcgacct tcctaccccg ggtgacccgc ggcaaggtgg tgctccggcc
    18241 ggctgaatgg cggctggacg gacatggcct ggaggacctc gcggcatggc gcgagcggtg
    18301 gcgcgtgccg cggtacgtgt atctcgtcga cctcgacaac cggctgctgc tcgacctcga
    18361 ccacccccgc tgcatcggag aactgcggga ggagatcggc cgcgcggccg gtggaacggt
    18421 gctgctccac gagatgctgc ccgacttcga gcatcactgg ctgaccgacg acctcgggcg
    18481 gcggtacacc gaagagatcg tcgtccccgt catggccgcc cgggccgaga ccatcgcccg
    18541 gcacccggcc ggggcgccgg tggagatccc ctcacggcgg tacccgccgg gcagcgagtg
    18601 gtcgtacgtc aagctgtacg ccgccttcga acgccacgac gagatcatcg ccggtccgct
    18661 gcgggaactc atcgcggagc tgcgcgcaga ggacgcagtg gaccgctggt tctacatccg
    18721 gtatgccgat ccgcgcccgc accttcgcat cagagtgcgc agcgaacggc cgtcggtcct
    18781 ggggcgactc gccgcctggg gcaggagcct ggtggacgcc ggtctcgccc aggacgtcac
    18841 catggacagc tactgcccgg agaccatgcg ctacggtggc cccgacacct tcgagtcgat
    18901 cgagcgactg ttcgaggcca atagtgacac caccgcccgt ctgatagcgg cccgcccgga
    18961 cctggcgcaa ctggtggacg agcacctggc tgtggccgcg gtggacaccc tccaccgtca
    19021 ctggggcgtc ccgctcgccg agcgcatgga cctgctcccc ggccaccggg acgacaacgc
    19081 cacgcgggac gaattcagga aggttcgtgc ctacctgtgc gaactgctgc tgccctggga
    19141 ccggtccacc catgaggagg gccgtgcaca ccgcatgggg atagtggcgg ccctcgcgcc
    19201 ccaggagcct gcggtccgtg cggcatccgc ggcggtccgc gaggccgccg aacgcggccg
    19261 actcgcggtg ccgcccgccc atctcctcgg cagtcttgcg cacatgcaga tcaaccgcct
    19321 cctgccggtc gatctggccc gtgaggaacg ctgctacggg ctgctgcggc acaccttgcg
    19381 tgccctcagg ggccgcctcg ctgccgagga ggccaggtga tctggctccg cgtgctgcgg
    19441 ctcttctgga agatgagcgc tcggaaggtc accgccttcg ccgttgcctc ggtgctgtcg
    19501 gccgcgatcc ccggcgtgca ggtcgggctc acggcgagtg cggtgcagtc ggtggcgcag
    19561 gctgccaacg gcaacgaggg ggccggacgg caggccctgc aggtgggtgt cgtcctgctg
    19621 ctgatcgcgg tggccgggca cctgctggac gtgtggggcc agtacctcga ttccctgctc
    19681 cgcctggaac tcaccaccaa gatcggtgaa caggtgatgg tcaagggcac ccggctcgac
    19741 ctggagcagt acgagaacgc cgagtcctac gacaagctgc aacgcgcctt ccaggaaagc
    19801 aacgggggac gcatctacca gttgttctcc gaaatgctca ccgtcacccg ggagctggtc
    19861 accgtcgtgt cggtcggcgc ggtgctgttc acctggtcac cgtgggtggc cctgttcatc
    19921 ctggtgtcac cggtcccgtc cgttgccgcg cacatgatct acacgaacaa ggcgtacgcc
    19981 atcgagtacg cgcgcgcagc agaccgccgg cggacgtact actaccagta cctgaccacg
    20041 acggatcact ccttcaagga agtgcgcctg ttccagctcg gaccgtacct cgtcgagcgg
    20101 taccgcacgc ttgtccacga gttcttccgc gtcgaccggc agctggcccg ccgccagtcg
    20161 ggcatcgtgg gcctgctggg tctgctgagc gtcatcgcct cctccggggc tctgctgtgg
    20221 gcgatcgggt cggccgcgga cggaggacag gtgggtcgcc tcgcgggata cctccagtcc
    20281 atgggcgcca tccaggtgtc ggcccacgga ctgctcctgg gaatcgcctc gctctacaag
    20341 gacacgctct tcctcggcaa cctcttcgcg ttcctggacc tgcccgagcg ccggatcacc
    20401 ggcgggaaca ggccgttccc ggcgaagcta cgcaagggaa tcgagttccg ggacgtcagc
    20461 ttcgtgtacc ccggcaccga ccggctcgtc ctcgacggtg tcgacctgct cctgccggcc
    20521 ggggagtgcg tggcgctcgt ggggcagaac ggcgccggga agacgagcat cgtcaaactg
    20581 ctgacccggc tctacgagcc gacgggtggg cggatcctga tcgacgacgt accgatcgag
    20641 gaatacgacg tcgacgacct ccagcggcac atcggcgtca tcttccagga cttcatccgc
    20701 tacgagatgt ccgtccgcga caacatcggc ttcggccgca tcgaggcgat ggacgacgac
    20761 gagcgcatcc aggccgcggc cgtagccgga ggagtcgaca ccgtggtgtc cgaccttccg
    20821 gaccggtacg acaccatgct cggtcggcac ttcgaggagg gccggcaact gtcgggcggt
    20881 caatggcaga aggtggctct gagccgggcc tttatgagga gggctccggt ggtcgtgctc
    20941 gacgaaccca cgtcggccat cgacgccgag gccgagtccg agatcttcgg ccggcttcgt
    21001 gacatcgcga gggacgccac ctccctcatc atcgcgcacc ggttcgccac ggtgcgcatc
    21061 gccgaccgga tcgtggtcct ggacgggggc agggtggtcg aggaaggaac ccacgaggaa
    21121 ctgctgagcg ccgacggaac gtacgcccat ctgttcaacc tgcaggcagc gggatatctc
    21181 gccgaacccg cctctcagtg aaggccgctt catgcaaact tcggtcatct ttccggtcat
    21241 gcccacggcc ccctccgagg cggttccctt cgcggaactc gtcagaagcg aggacatgcc
    21301 gcggctgtgg cagggccagt ccgtcacgat cgaaacccat cagatgttcg cctacctcgc
    21361 gggcatggga ttccgcatcc cgttcggcac tgccgtgacc ctgatgcctt tgcgccaccc
    21421 aatggaagca gcggcacacg cccggtccct ggcccgtctg accggcaggc gggtgacgct
    21481 gggactcggc cctggatccc ccgacttcgt ggtgagtctg cacggaaagc cgtacgacag
    21541 cccgaaagcc gcgtgtgccg actatctccg gcaggtgcgc ggattcctca ccgagcagag
    21601 gcacaaggtg ccagaggccg ttcggcaggc atcggaccta ccggatctcg gtcatcccgg
    21661 tgtggatatc ggccttggag tcctccgccc cacgctcgcc cgtctggcgg gcgagactgc
    21721 cgacgtggcg atcacctgga tgacgccgcc aggatacctg gcacgtgacg tggtgccggc
    21781 gctccggcgc ggtgctcggg cggcgagccg gccggtcccg cgcctggtca ccgtcgtaca
    21841 tgtcgccgtc gaccgccacg ggcgcgatcc ccgccaactc gcctacgcag ccgcccgcac
    21901 acacctgggc gccccgcact acacggacat gctcaggcgc gcggggctgc gggtgcaccc
    21961 gtcacagccc tatctcaacg catgtgcctt ggtcgactcg ggaaccttcg cgtacggcac
    22021 cccgcgggaa gtggccggcg cactggccga atacgcccga gtgggcgtgg acgaattggt
    22081 cctcaactgc gcaggtgtag gtctcgtgca tggctggaat gcggccctgg aggacctggc
    22141 ggaactctcg gccgaaatgc gtgcggtccg ttcgggcgtg atcgcataaa ggctaggctc
    22201 accgtgtcga gaggcgacgc gaaaggaaat ggcgatgacc gaggaagtgc aacgatggct
    22261 gaaagagaac gccttgccat tgaaaggcct gcaccccgag gcatcgaacc cgggctacgg
    22321 tgacctggag ccactgcgca aggttctgcg cgacgtacgt gttctgggga tgggggaagc
    22381 gacgcacggg accgccgagt tcttccggct caaacacctg ttactgcgct tcctcgtcga
    22441 ggagatgggt ttcaccgctc tggccatgga ggccagtgcc tccgctgctc aggcggtcga
    22501 cgactacgtg ctgcacggaa ccggtgatgc cgtcgacgca gtggccggcc tcggcttctg
    22561 gacgtggcgg acacgggaaa tgctcgacgt cgtcgagtgg atgcgcgacc acaaccgaac
    22621 ggttccccag gaccgggccg tacgattcgt gggcatcgat ccgcagcgat gcggcccctc
    22681 cctgtcggcg ctggccgccg tgctgcgcac gctggcaccg gaacgtgcgg acatcaccga
    22741 tggcccgctc ggcacactgg cggaggccag gaccgggtca ctcgtggacc agcgccccca
    22801 gctcctcgcc gaggcgcgtg atctggagcg attcctcgag gaggagcacc cccggcttgc
    22861 cgcgcacatc ggggacacgg ccgtcgatca ggcactcagg catgcgcgcc tgatcgtggc
    22921 cgcggccgac gtggcctccc ggccgccgcg gggcgaaggc gaggagacgg gcgcgctggc
    22981 cgcccgggac cgtcacatgg cccaggcagt ggtctccttg gaggagggga ctgccggcaa
    23041 ggtggccgtc tgggctcaca acggccatgt ttgcaccgac agttacgcgc gagacatacc
    23101 cgccatgggg cggcacctca gggatcacta cggtgagcgg tactacgctc tgggcctgct
    23161 gttcggccag ggcgccttcc gcgcccgtcc cggaaactcc gcgacacgac cgcccaggaa
    23221 acacaccatc agtgcggcgg gtccgcgctc cgtcgaggcc cagctggcct cggtcacctc
    23281 cgaggaccac ctgatcgatc tccgcgccgg ccggaccgag cccgtcgttg ccgagtggct
    23341 ggagagcccg cagttcatgc ggtccttcgg cgccggcgtg ccacgcgtga cgtaccgctt
    23401 ctcgatgact cagacggtgc tcatgcgtga gtacgacgga ttggcgtacg tggcccgctc
    23461 gacgccctcg gtgctactga gctgagaccc aacactgtcc ggaccgcagc ccacaattga
    23521 tagtcgtgac cgggcacagc aactcctacg tgacggtctt gccacgaggc aggggacagc
    23581 cgttgatgct gggccgaagt gtgctggtac gtcggtgtcg cagtgggtcg acggtggatc
    23641 gcgttgttcg gctggacctc gcgcttgaag tccggtaccg cggtaggagt accagacgta
    23701 ctcgtggacg gtcatcggcg tggccgcggc gggccaccgc cctcatgggc ctatctacgc
    23761 agagggagag tttgcacccg gcatgtaacc aacctgtctg acgtggcaac tcgcttggcg
    23821 ctgaagcagt cacatgaata gcatcctgtt caccatcggg aactaatatt gcgtgtgcat
    23881 attctcgggg gatgatcttg cgactcgcgg gaacctcaac gtcaattggc cctgttgcgg
    23941 ctggtcaaag gatctcgtga acgacccaca gacaagaccc catggctgcg gccgtggggt
    24001 tctttcgttg ccgccgttgt tgcccgcagc cgagccccgg gaaaaattcg gtactgcacc
    24061 ggctgatcgt ttccctagac tcgccacgca gcgcgcgccg cccgtaccac ggtggcgtgc
    24121 ttcgtgagtt gtgacgatcg aggggagccg ggccgtgcgt gaccgtaccg ccgttgtcgt
    24181 tccccctgcg cggaccgagg tgatcctggt gtcctcgtcc gtccggtgcc cgctgcgcgg
    24241 ccggtaccgg atgcccgtga cgccccgctg acaccccggc cgcccgcccg gcacatgtcc
    24301 ggccgccgcc gtaccgtccg ctccctgtgg cacacgggga atcgcgccgc ccttttccag
    24361 gaccacctcc cgaaaggcac cgggccgtgc gcacccacat cgacaccctc gccgccgtac
    24421 gcaacctcgg catcctcgcc cacgtcgacg ccggcaagac caccgtcacc gagcggatcc
    24481 tctatgcgac gggcaccacc cacaagcggg gcgaggtgca cgacggcacc accgtcaccg
    24541 acttcgaccc gcaggaacgc gaccgtggca tcaccatctt cgccgccgcc gtcagctgcg
    24601 cctggaacgg ccatcgcatc aacctcatcg acacccccgg ccacgtcgac ttcgccgacg
    24661 aggtcgagcg gtcgctgcgt gtcctcgacg gggcggtcgc cgtgttcgac gccgtcgccg
    24721 gcgtcgaacc gcagagtgag tcggtgtggc ggcaggccga ccggcacggc gtcccgagga
    24781 tcgcgttcgt caacaagctg gaccgtgcgg gcgccgacct cgaccgggcc gtcggctccc
    24841 tccgggaccg gctgcacccc gctccgctcg tcgtccagct gccgatcggc gccgaggacg
    24901 gcttcacggg tgtcgtggac ctggtgcgga tgcggtccct ggtgtggggc gacgacgagg
    24961 gtacggccat ggaagggccg gtgcccgagg agctgcggga ggaggcggta cggcggcggc
    25021 gcgcgctgga ggaggcggtc gcggaaaggc atccggccgc cctggaggag ttctgcgacc
    25081 gagagacgct cttcgcggcg accctcaccg ctgccctgcg cgacctcacc cgcaccggtg
    25141 acggcgtggt ggtgctgtgc ggctccgcct accgcaaccg cgggatcgaa ccgctgctgg
    25201 acgcggtggt ggcctacctc ccgtccccgc tggacgtacc cgccgtacgg ggcgccggcg
    25261 aggacgccgg gcagcggcgc gccgccgatc ccggagcgcc gttcgcgggg ctggtgttca
    25321 aggtgaacgc gagtgccacg ggccggctgg cctacgtgcg cgtctattcc ggaaccgtcg
    25381 agaaggggga tgccgtgtgg gacccgggca gtgggcgcac cgagcgggtg gcgcgcatcc
    25441 tgcgggtcat ggccgaccgg cacgtccagc tggaccgggc ggtcgccggt gacatcgtcg
    25501 cgctcgcggg cgtgaagtcg gcccgggtcg gtgccacgct gtgcgacccc ggtgccccgg
    25561 tgcagctgga ggcgcccgtg gccgccgaac ccgtggtgtc cgtggcggtc gaggcgcggc
    25621 ggagcacgga caccgggcgg ctggcggcgg cgctcgcccg gctcgccgag gaggatccct
    25681 cgctggtggt gcgtaccgac accgagaccg ggcagacggt cctgtccggg atgggcgaac
    25741 tccatctgga ggtcgcggtg gagaagatcc gccgcgacgg cgggcccgag gtcaccgtgg
    25801 gccgcccccg ggtggcgtac cgggagaccg tcgtcggcgg cgtcagcggg ttcgtgttcc
    25861 ggcacgtcaa acaggacggc ggtgcggggc agttcgctca tgtcgtcctg gacgtggagc
    25921 cgctcggccc cgaactgggc gtcacgggct tcgagttccg gtccgccgtg gtcggcgggc
    25981 gggtgccgca ggagtacgtg cgcgcggtgg aggccggctg ccgggacgcg ctcaccgggg
    26041 gaccgctcgg cgggcacccg gtgaccgggc tgcgcgtcac gctcaccgac ggctccaccc
    26101 atgtcaggga ctcctccgac acggccttcc gcaccgccgg ccggctcggc ctgcgcgagg
    26161 ctctgcgggc ttgcacgacc gcgctgctcg aacccgtcgc cgaggtcgcg gtgaccgtgc
    26221 cggaggacgc ggtcggcggg gtgctcggag atctggccgc ccgtcgcggc cgggtcggtg
    26281 gctcgcggag ccggggcggc gcggccgtgc tgaccgcgac cgtgccgctg gccgaactct
    26341 tcggctacgc gacccggttg cgcagccgca cccacggccg gggcaccttc accacccggc
    26401 ccgccggcta cgccccggcc ccgcccccgg tccggtaagc ggtacgtccc tggtgccggc
    26461 ccgcaccacg agtcgtcgtg gctcgtggtg cgggccggcg ccggggcgtg ggccgtactg
    26521 caacggtcgg gcggctcgcc gaccggtaca ccctgccgct gctcgccgtg gggtctgctg
    26581 atcgacctgc tgtgcctcgc cggtttcgac ggtcctcgcc gaagcgcccc cgcacgcggt
    26641 ggtccgcctg ctgggcctcg ggctggccgg ggtcaccatg aacccggcga cggtcacccg
    26701 ggtccagcgg acgggcaacg ccgggccgct cgtgaacacc gtccactcct ccttcatcgc
    26761 gctcggcctc atcacggaac tgcgcgacgg cggtgcggcg gggaccgcgg tacggcgcgg
    26821 gaccgcggtg cggcgcaggg agcggagccc gcggcaccgg gagtggtgag ccggggctgt
    26881 acggccggcc cgggtgggtt ccgagaggga ccgcgccttc gatctccctg tcgaatccct
    26941 tgacgatcgt ccccgctgcg gattaactca cgtcctaaat taagtcatga gtgcaatccc
    27001 tgaagggaca ccgggagcca tgcgcagcat ccgagccgcg gccgtaggcg ccgtcaccct
    27061 gtctctcgcc cttgcggcca cggcctgcgg aggcggatcg tccaccggcg gggcgtccgg
    27121 cgactcgccg aagacgctga cgtactgggc ctcgaaccag ggcgccagcg tcgccgtgga
    27181 caagaaggtc ctccagcccg aactcgacaa gttcgagaag cagaccggca tcaaggtgaa
    27241 actggaggtt gtgccctggt cggatctgct caaccggatc ctgaccgcga ccacctcggg
    27301 ccagggcccg gacgtgctga acatcggcaa cacctggagc gcctcgctgc aggcgaccgg
    27361 cgcgctgctg ccctgggacg agcagaactt cgcgaagata ggcggcaggg accgcttcgt
    27421 ggagtccgcg ctcggctcga cgggcgtgca gggcaaggac ccggcggcgg tgccgctgta
    27481 ctcgatggcg tacgccctct actacaacaa gaagatcttc gccgacgccg ggatcggcaa
    27541 gccgcccgcc acctgggacg agctgatcgc cgacggaaag aagatcaagg cccggggcaa
    27601 gtcggtgctc ggcgccgagg gcgcgaacct ctcggagaac atccaccacg tcttcgtgtt
    27661 cgccaagcag cacggcgccg acttcttcac cgccgacggc aagccggact tcaccgctcc
    27721 caaggtcgtg gaggcggtga agagttacgt cgacctgatg gccaaggaca aggtcgtccc
    27781 ggccggcgac gccgagtacg cgcagaacca gtccgtcagc gacttcgcca agggcaggca
    27841 ggcgatgctg ctgtggcagt ccgccgccgc caacctcaag tcccagggca tgagcgagga
    27901 cgcctacggc atcgcccccg tcccggtccg ctccggcacc cccggacagg gcacccaggt
    27961 gaactcgatg gtcgccggca tcaacatcgc cgtcttcaag aacacccaca acctggacgg
    28021 cgccgcgaag ttcgtgaagt tcatgacctc cgacgccgag cagaagatcc tcaacacggc
    28081 ctacagcacc gtcccgccgg tcaggtccgc ccaggacgac cccgcgttcg gtgcccccga
    28141 caccgcggtg ctgaagaaca ccctcgccac gagcgcggcg gcgctgccgc aggtgccgtc
    28201 cgagtcgcag ttcgagacga cggtcggtac ggcggtcaag gagctgttcg ccgacgccgc
    28261 cgccggacgc gccgtgacca ccgactcggt cagggcgaag ctggagaagg cccagcagca
    28321 gatgccggcg gcgtgaccac gatgacgacc accgcactga aggaaccggt gcgcgagacg
    28381 tcccccggcg cggcgcgcgc accacgccgc cgcgccgggc ggatccgccg cctctccctg
    28441 ccgtacctgc tgctcctgcc cgcgctgctg ctcgaactcc tcgtgcatct ggtgccgatg
    28501 gcgatcggca tcgtgatgag tttcaaggaa ctcacccagt tctacatccg cgactggagc
    28561 accgctccgt ggagcggcct ggacaactac cgggtgtcgg tggacttcga cgccccggtc
    28621 ggcaaggcgc tgctgcagtc gttcggcgtc accgtcggct tcaccctgct gtcggtcggc
    28681 ctgtgctggc tgatcggcac ggccgccgcg gtcttcatgc aggacgcctt ccgcggccgc
    28741 ggcctgctgc gcgcgctgtt cctggtgccg tacgcgctgc ccgtctacgc ggccgtgatc
    28801 acctgggtgt tcatgttcca gcacgacaac ggcctggtta accacgtgct gcacgaccag
    28861 ctgcacctca ccggcgagcc gtcgttctgg ctcatcggcg acaacagctt ctacgccctg
    28921 ctgaccgtgt cggtgtggaa gggctggccg ttcgcgttcc tcatcgtgac ggccgggctg
    28981 cagaacatcc cccgcgagct gtacgaggcc gccgcgctgg acggcgccgg gacctggcag
    29041 cagatccgcc gcatcaccct gccgtcgctg cgcgccgtca accaggtact ggtcctggtg
    29101 ctgttcctgt ggacgttcaa cgacttcaac acgccgtacg tgctgttcgg caaggccgct
    29161 cccgaggccg ccgacctcat ctccgtacac atctaccaat cgtcgttcgt gacctggaac
    29221 ttcggcaccg gctcggccat gtccgtcctg ctgctgctct tcctgctggt cgtgacgggc
    29281 ggatacctgc tgctgacctc acgcggacgg aggactgccg atgcctgact cgccgatggc
    29341 gccgccgcgt tcgttcctgt ggtcgcggcg ggtgttcctg accctgctcg ccgccttcgt
    29401 gctcaccccg gtgtacgtga
//
