LOCUS       NZ_CP071839            21143 bp    DNA     linear   CON 20-APR-2024
DEFINITION  Streptomyces cyanogenus strain S136 chromosome, complete genome.
ACCESSION   NZ_CP071839
VERSION     NZ_CP071839.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces cyanogenus
  ORGANISM  Streptomyces cyanogenus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8773899)
  AUTHORS   Hrab,P., Ruckert,C., Busche,T., Ostash,I., Kalinowski,J.,
            Fedorenko,V., Yushchuk,O. and Ostash,B.
  TITLE     Complete genome sequence of Streptomyces cyanogenus S136, producer
            of anticancer angucycline landomycin A
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8773899)
  AUTHORS   Hrab,P., Ruckert,C., Busche,T., Ostash,I., Yushchuk,O.,
            Kalinowski,J. and Ostash,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2021) Genetics and Biotechnology, Ivan Franko
            National University of Lviv, 4 Hrushevskoho St, Lviv, Lviv region
            79005, Ukraine
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2020
            Assembly Method :: Newbler v. 2.8; Canu v. 1.8; Unicycler v. 0.14
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 974878.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017526105.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 09:57:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,747
            CDSs (total)                      :: 7,656
            Genes (coding)                    :: 7,375
            CDSs (with protein)               :: 7,375
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 281
            CDSs (without protein)            :: 281
            Pseudo Genes (ambiguous residues) :: 0 of 281
            Pseudo Genes (frameshifted)       :: 129 of 281
            Pseudo Genes (incomplete)         :: 239 of 281
            Pseudo Genes (internal stop)      :: 25 of 281
            Pseudo Genes (multiple problems)  :: 104 of 281
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:56:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5749348
            Orig. end                         :: 5770491
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071839.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Bohdan Ostash, 4
            Hrushevskoho St., Lviv, 79005, Ukraine.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21143
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="18"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21143
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21143
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11143](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11143
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(649..906)
                     /locus_tag="S1361_RS25995"
                     /old_locus_tag="S1361_25955"
     CDS             complement(649..906)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="S1361_RS25995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_25955"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003992873.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVIEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
     misc_feature    950..965
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(951..962)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    1129..1138
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     gene            complement(1228..2196)
                     /locus_tag="S1361_RS26000"
                     /old_locus_tag="S1361_25960"
     CDS             complement(1228..2196)
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134762.1"
                     /locus_tag="S1361_RS26000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_25960"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_208034186.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARRRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAAESDDIDLVVALGGDGTVNEVVNGLLHAGPDPDRLPGLAVVPGGSTNVFARALG
                     LPNDPVEATGALLDALREGSERVVGLGLTSGTPGTEDEAVPARWFTFNAGLGFDAGVVG
                     RVEQQRERGKKSTHALYVRQVIRQFLGEPNRRHGTITLERPGADPVGDLVVAIVSNTSP
                     WTYLGNRPMYTSPKASFDTGIDVLGLSRLSTAAVARYGTQLLTSSPERGPHGKHALSLH
                     DLDQFTLHSKAPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     gene            2332..2784
                     /locus_tag="S1361_RS26005"
                     /old_locus_tag="S1361_25965"
     CDS             2332..2784
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674913.1"
                     /locus_tag="S1361_RS26005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_25965"
                     /product="hypothetical protein"
                     /protein_id="WP_208034194.1"
                     /transl_table=11
                     /translation="MSSQQNPAPDTAEAAAAAEPRPRRLTYAAALAALEGTALLAGGLW
                     VLVLGLTGAPDDRQQAVTLGITLAVLALLPLLAARGLLLRRGWSRGPAVITQVMALPVA
                     YNLLRADSMAIPAGIALAVVAVAALVLLVNGETTRALGIKGPGRAE"
     gene            complement(2846..3976)
                     /locus_tag="S1361_RS26010"
                     /old_locus_tag="S1361_25970"
     CDS             complement(2846..3976)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030133.1"
                     /locus_tag="S1361_RS26010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_25970"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_208034196.1"
                     /transl_table=11
                     /translation="MRNGDGPVRDEERGTRELPTGDGGASWSSSAETSGAGPRDGSRRM
                     ADGIDGIPEQARPHPEDDSARVDGDGAGQGTPPEARDGADPGRAGATARGRATGGTMSE
                     HERDAEQEALGAEAVRAVQHGPQDRSGARAMFVELRKLNAGSAEYAELRNQLVRMHLPL
                     VEHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRD
                     KGWAVRVPRRLQELRLSLTTATAELSQLHGRSPTVHELAEKLAISEEEVLEGLESANAY
                     STLSLDVPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGN
                     MTQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(3973..4389)
                     /locus_tag="S1361_RS26015"
                     /old_locus_tag="S1361_25975"
     CDS             complement(3973..4389)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="S1361_RS26015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_25975"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_009190566.1"
                     /transl_table=11
                     /translation="MSQIAGEPAANQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLD
                     EIEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWT
                     VLSALAGKVSSAVDEDKTVSISLYKQRGAGPGPA"
     misc_feature    4518..4531
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    4646..4656
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(4683..4943)
                     /locus_tag="S1361_RS26020"
                     /old_locus_tag="S1361_25980"
     CDS             complement(4683..4943)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="S1361_RS26020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_25980"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_208034198.1"
                     /transl_table=11
                     /translation="MKQCTHADALPHPEPEPLDKTCPECLRDGTHPVQLRLCLTCGHVG
                     CCDSSPGRHATEHHANSGHPVMRTFEPGEDWRWCFVDHVLV"
     gene            5005..6588
                     /locus_tag="S1361_RS26025"
                     /old_locus_tag="S1361_25985"
     CDS             5005..6588
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674917.1"
                     /locus_tag="S1361_RS26025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_25985"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_208034200.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAVAAAARRTPAPAPLLLVAVGLAVSYIPGVP
                     SYTLDPHVVLPLLLPPLLYTSASDSSYLDLRAQLRPVALLSVGYVLFATVVVGWAAYLL
                     VPGLSLPAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLLNDATAITAYKVA
                     LGAAVGEGATWAGGIGEFALAAVGGVGIGLVLMAPLHWLRTHLTEPLLQNTLSLLIPFV
                     AYGVAEQAHASGVLAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPIVLKRLGEYEGSSAVWYAVAVFVVVVVARFVWVYPATFLPRLLSARIREREENPTW
                     RGAMVTSWAGMRGVVSLAIAFAIPSTMADGPRNLILFLTFTTVIGTLVVQGVTLPPLIR
                     LLRFPGRDRQAETLAEANAQAQASRAAEARLDELLSDERNALPPPLADRLRTVLERRRN
                     AVWERLGQVNPVTGESVDDTYRRLSREMIGAEREVFVRLRDLRYIDDEMLRALLRRLDL
                     EEAAAYREAG"
     gene            complement(6585..7505)
                     /locus_tag="S1361_RS26030"
                     /old_locus_tag="S1361_25990"
     CDS             complement(6585..7505)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674918.1"
                     /locus_tag="S1361_RS26030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_25990"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_208034202.1"
                     /sec_met_domain="PALP (E-value: 5.6e-20, bitscore: 70.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPDLLDPRLPSPLHDIRDDRFERRGLRLLLKRDDLVHPHLVGN
                     KWRKLVPNLAAASGRPLVTFGGAYSNHLRATAAAGRLLGLPTTGVVRGQELAGRPLNPS
                     LARCAADGMRLHFVDRSTYRGKTEPETLARILRAAGAEDAYVVPEGGSNAEAVRGCLAL
                     GAELRGHADVVAVACGTGGTLAGLAAGLAAGQRALGIPVLKGGFLEADVRALQERAFGA
                     RSGTWSLDDRFHCGGYARTTPDLEAFAQDFEQRHGLPVERLYVAKLLYGLAALAQEGAF
                     ARGTTIAAVVTGRPFPEPGTAAPER"
     gene            complement(7598..8191)
                     /locus_tag="S1361_RS26035"
                     /old_locus_tag="S1361_25995"
     CDS             complement(7598..8191)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674920.1"
                     /locus_tag="S1361_RS26035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_25995"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_208034204.1"
                     /transl_table=11
                     /translation="MAPPMSANGFLDALRAEGVTVVEVGDWQHHNRNHKGPWGPVHGVV
                     IHHTVTRGSARTVELCRDGTADLPGPLCHGVITKDGRVHLVGYGRANHAGLGDDDVLRA
                     VIAEKRLPPDNEANTDGNRHFYGFECENLGDGEDPWPPEQLEAVERVAAAVCRHHGWTE
                     RSVIGHLEWQPGKVDPRGFSMAWLRERVRERLKD"
     gene            8482..9888
                     /locus_tag="S1361_RS26040"
                     /old_locus_tag="S1361_26000"
     CDS             8482..9888
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="S1361_RS26040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26000"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_208034206.1"
                     /transl_table=11
                     /translation="MSVGEEVRTDQGKPQQSLGTAAARNLATTTKSVPQMQEISSRWLL
                     RTLPWVDLQGGTYRVNRRLTYAVGDGRITFVKTGNQVEVVPNELGELPALRSYEDEEVL
                     TELARRCRQRDFAAGEVIADFGNQADEVYLLAHGRVEKVGTGPYGDDAVLGVLADGAYF
                     GDQALLDPEAIWEYTVRADTSTTVLILSRQDFQQVAERSDSLRAHLERLRSIPEQRTNR
                     YGEKEVALAAGHSGEPDIPHTFVDYEPRPREYELSIAQTVLRIHTRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELVNNPEFGLLSNCEYDQRIQPHDGVPGPDDLDELLSRRRGTK
                     LLLAHPRAIAAIGRELNKRGLVPETIDIAGNRIPTWRGVPIYPCNKIPISEARTTSIIA
                     MRTGEADQGVVGLRQSGIPDEIEPSLSVRFMGINEQAVIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            10001..11143
                     /locus_tag="S1361_RS26045"
                     /old_locus_tag="S1361_26005"
     CDS             10001..11143
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674923.1"
                     /locus_tag="S1361_RS26045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26005"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_208034208.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.6e-59, bitscore:
                     199.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEFMTETEERSSGVLRPGTAEEPREQTGDTGGPLDAQEAAVQLE
                     RTRALVDPELRAAVESLPAAMRRIGLYHFGWQHADGSPAEGNAGKAIRPALVLAAAAAL
                     GGPAARTAAVRAAAAVELVHNFTLVHDDVMDRDSTRRHRPTVWTVFGDTDAILAGNALQ
                     ALALRLLAEDPHPASAPAAARLAACVVELCEGQHADTRLEQRAPEAVTLEEVLAMAEAK
                     TGALLGCACALGALYAGAGEEEVAALDGFGRQAGLAFQLIDDVIGIWGDPRHTGKPAGA
                     DLAARKKSLPVVAALTSGTPAAAELAALYGKPYPGQEAAAGEIARTALAVERAGGRDWA
                     QAEAADRMARAMQELARAVPDPEAAGGLLALAEFVTRRTS"
     gene            11376..11642
                     /locus_tag="S1361_RS26050"
                     /old_locus_tag="S1361_26010"
     CDS             11376..11642
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674924.1"
                     /locus_tag="S1361_RS26050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26010"
                     /product="hypothetical protein"
                     /protein_id="WP_208034211.1"
                     /transl_table=11
                     /translation="MDSDARVCPACGQAVETVVKRHKTLGAWVPVWGPGPCRNPDCARY
                     DATDQPAEPGRPAHDDRSAGAPAGPGGSGPEDPSAAGAGNSAV"
     gene            11694..12026
                     /locus_tag="S1361_RS26055"
                     /old_locus_tag="S1361_26015"
     CDS             11694..12026
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674925.1"
                     /locus_tag="S1361_RS26055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26015"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_208034213.1"
                     /transl_table=11
                     /translation="MPKLPYILHITERSLWEAARERGAYELSTRGRTLQEEGFIHFSTR
                     DQLPRVAGFLYGGYDGPDELVVLVVDPARVGAPVKYESVEPGGEEFPHVYGPVPVEAVV
                     DVETWG"
     gene            complement(12060..12806)
                     /locus_tag="S1361_RS26060"
                     /old_locus_tag="S1361_26020"
     CDS             complement(12060..12806)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998002.1"
                     /locus_tag="S1361_RS26060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26020"
                     /product="VOC family protein"
                     /protein_id="WP_208034215.1"
                     /transl_table=11
                     /translation="MTIRWTHAFADRPAARLGEACAFWTAVTGTRLSAFRGDDGEFVTL
                     LPEGTDPSVKLQGVTGGDGGAHLDLCAEDVREVVALARRLGAGLVADHGDWAVLCSPAG
                     QLFCAVPWQGEAVRPPVVSGSRLDQVCLDIPPSRYDAESAFWAGLTGWEQVAGSRPEFT
                     VLRPPTGFPVRLLLQRLDEERPASAHLDLACADIAAVRVRHEELGAVAVREGAHWTVMR
                     DPAGGTYCLTGRDPETGGLPAGARVG"
     gene            complement(12841..13257)
                     /locus_tag="S1361_RS26065"
                     /old_locus_tag="S1361_26025"
     CDS             complement(12841..13257)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674926.1"
                     /locus_tag="S1361_RS26065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26025"
                     /product="VOC family protein"
                     /protein_id="WP_208034217.1"
                     /transl_table=11
                     /translation="MDVKLAQCFLAVDDHDKAIAFYRDVLGLEIRNDVGFEGMRWVTLG
                     SPLQPDVEIVLEPPDASPDASPTDKQALNELLAKGLLRGVIFTTPDCDALYERVRESGA
                     DVLQEPMDQPYGVRDCAFRDPAGNQLRFIERPAG"
     gene            complement(13292..13693)
                     /locus_tag="S1361_RS26070"
                     /old_locus_tag="S1361_26030"
     CDS             complement(13292..13693)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674927.1"
                     /locus_tag="S1361_RS26070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26030"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_243769299.1"
                     /transl_table=11
                     /translation="MTALEDLRRLRRVRDRMDREYAEPLDMTELARDALMSPGHFQRSF
                     RKAFGETPYGYLMTRRIERAKVLLRRGDLSVTEVCLAVGCTSLGSFSSRFTELVGETPS
                     AYRARDHEESAVIPPCVARRLTRPRRRPY"
     gene            complement(14167..15330)
                     /locus_tag="S1361_RS26075"
                     /old_locus_tag="S1361_26035"
     CDS             complement(14167..15330)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057371.1"
                     /locus_tag="S1361_RS26075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26035"
                     /product="acyltransferase"
                     /protein_id="WP_243769300.1"
                     /transl_table=11
                     /translation="MALTRTVGSAPGSAAPGGEGGAHDRPHVQGLDGLRGLAALYVVLF
                     HCWLYTFPGYPDSAAPGWLDVLMFGRLAVVFFLVLSGFSLAISPARHGWRTDGVVRFLR
                     RRAWRILPPYWAALAMSLVISSFVVPASHFGPPTGASLLVYGLVAQDMVTAPTPNGAFW
                     SIGVEAELYLLFPLLLLIRRKSNAAVMVACVALPVIVGGLTATGANPVEGDNWLAPHLA
                     PVFAAGLAGAGVVVASDRVRRLPWPWFAVLAAVPVLALGAVQGSVWTVNHYFWVDLAIA
                     PAMAMLLAAVATGRPAVLVRLLTTRPLRSLGGFSYSLYLIHLPVVMAVIRRVAPHFVSP
                     GLPTFWFTLVVALPASVLGAWLFSRIFELPFQRNRSWKSMIALWRSR"
     gene            <15510..15629
                     /locus_tag="S1361_RS40075"
                     /pseudo=""
     CDS             <15510..15629
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571386.1"
                     /locus_tag="S1361_RS40075"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LVPGEDDRTRPVMDAVLGGLRTGCGQGDAAIGETAGQKA"
     gene            complement(15635..16030)
                     /gene="sodN"
                     /locus_tag="S1361_RS26080"
                     /old_locus_tag="S1361_26040"
     CDS             complement(15635..16030)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="S1361_RS26080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26040"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_100828187.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAAN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKAPHFEKYPELHQLVNDTLKALSAAKA
                     STDPATGQKALDYIAQIDKIFWETKKA"
     gene            16176..16610
                     /gene="sodX"
                     /locus_tag="S1361_RS26085"
                     /old_locus_tag="S1361_26045"
     CDS             16176..16610
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190575.1"
                     /locus_tag="S1361_RS26085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26045"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_208034220.1"
                     /transl_table=11
                     /translation="MPELSQETERGRAVALFGLAEVTGPSMVPTLHHGDRLLVRYGGVV
                     RPGDVVVLRHPFQQDLLVVKRAVQRREGGWWVLGDNPYAGGDSTDYGVVPEELILGTAW
                     FRYRPVKAGQRSPLALLRWALSAARPLLPDRSASRRLRAR"
     gene            complement(16514..17143)
                     /locus_tag="S1361_RS26090"
                     /old_locus_tag="S1361_26050"
     CDS             complement(16514..17143)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="S1361_RS26090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26050"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_208034221.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNSEEPGRGRDTLVTVEAVRDLFGENASAARR
                     ATDADVTRFRSVRARLRGVFEAADKGDETLAVDLLNSLLLEFPVSPQISGHDHRDEDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEYGVDRLGLCQAPPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSGSSGLAAESAQRSSASGER"
     misc_feature    17136..17151
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            17244..18002
                     /locus_tag="S1361_RS26095"
                     /old_locus_tag="S1361_26055"
     CDS             17244..18002
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657871.1"
                     /locus_tag="S1361_RS26095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26055"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_208034223.1"
                     /transl_table=11
                     /translation="MTTTAGTDWAAWQESWDRQQEWYMPDREERFRIMLDMVEALVGTA
                     PRVLDLACGTGSITARLLRRFPGATSTGVDLDPALLAIADGTFAGDDRVTLVTADLTDP
                     GWPAKLPYDSYDAVLTATALHWLHSEPLATLYGQVAGLVRDGGVFMNADHMIDDTTPRI
                     NAAERAQRHARMDQAKRDGALDWTEWWQLAAGDPVLAEPTARRFEIYGEHADGDTPPPA
                     WHARVLREKGFAEARPVWCSPSDTLLLALK"
     misc_feature    complement(18219..18235)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.2"
                     /tool="antismash"
     misc_feature    complement(18409..18422)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.85"
                     /tool="antismash"
     misc_feature    18412..18427
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.19"
                     /tool="antismash"
     misc_feature    complement(18413..18426)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.13"
                     /tool="antismash"
     gene            18503..18859
                     /locus_tag="S1361_RS26100"
                     /old_locus_tag="S1361_26060"
     CDS             18503..18859
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075220.1"
                     /locus_tag="S1361_RS26100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26060"
                     /product="hypothetical protein"
                     /protein_id="WP_243769301.1"
                     /transl_table=11
                     /translation="MAGSALATSPAEAYSKTCNADQTAYYSICFDGSNDSFIVDDLRPD
                     GERAVVKWYAYDGSGREGECSDANGSLNGPVVCDYDFKEGVNNYVSFMGFTRDGASGPK
                     HNESWVYNGYITPR"
     gene            complement(18928..19680)
                     /locus_tag="S1361_RS26105"
                     /old_locus_tag="S1361_26065"
     CDS             complement(18928..19680)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190578.1"
                     /locus_tag="S1361_RS26105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26065"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_208036774.1"
                     /transl_table=11
                     /translation="MVKAEGVHKSFGHVEVLKGIDLEVKPGEVFCLIGPSGSGKSTFLR
                     CINHLEKINAGRLYVDGELVGYRQQGEKLYELRDREVAVKRRDIGMVFQRFNLFPHMTA
                     VENVMEAPVQVKGVSRAQARERAMQLLERVGLADRAGHYPSQLSGGQQQRVAIARALAM
                     EPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMVVVTHEMGFAREVGDSLVFMDGG
                     VVVESGHPRDVLTNPQHERTQSFLSKVL"
     gene            complement(19731..20663)
                     /locus_tag="S1361_RS26110"
                     /old_locus_tag="S1361_26070"
     CDS             complement(19731..20663)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491263.1"
                     /locus_tag="S1361_RS26110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S1361_26070"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_208034224.1"
                     /transl_table=11
                     /translation="MTDIQKTAGEQGTPPAGPEAIKAIPVRHYGRYVSAVIALALLAAI
                     VYAFSQGAINWGAIPDYFFDDRVVEGMSKTLLLTILSMAIGIVGGIVLAVMRLSKNPVT
                     SSISWFYIWFFRGTPVLVQLVVWFNLGLVFEYINLGPLYKDEWSDFMTPFLTALLGLGL
                     NEAAYMAEICRAGLLAVDEGQTEAAHALGMSHGKTLFRIVIPQAMRVIVPPTGNEVINM
                     LKTTSLVSVVQYSELFRVAQDIGQTSGAPVEMYFLAATWYLILTSVLSVGQYYIERYYA
                     RGSSRSLPPTPWQKIRAHLTTLSSRKVTA"
     misc_feature    20786..20800
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
ORIGIN
        1 ccgggtcggc tccatcgcca tcgtgcatga gacgctgtct cagaacctgg acgagcgggt
       61 ggagttcgac gacatcgccg accgggtgct cgccatggtc gccgagatct cgccgggcaa
      121 ggtgaccggc cggcgcagcg gacggttcgg catactcgac gctgaggtcg ccaccccgct
      181 gtccatggtc ctcaccgaga tcctgcagaa cgccctggag cacggcttcc gcgagggcga
      241 caccggcacg gtcgaggtct cggcggtccg gggcggcacc accaaggagg cccggctgct
      301 ggtcaccgtc caggacgacg gcgtcggcct gcccgagggc ttcgacccgc accgctcggg
      361 caacctcggc ctgcagatcg tacggacgct ggtggagggc gagttgggcg gcacgttcga
      421 catggtgccg gcgccggagc gggggacccg ggtgatcctc gacatcccgg tgcgcgcaca
      481 gaagtgagcc gacgggctca ccggagagcg ggcacagcaa aaagccccgg accaccgttg
      541 gtccgaggct gatgctcgtt gatgaactgc gcgctgcggc tcgggggcgg gagatgcgta
      601 cgtgctgtgc gcgccgccaa gctcaggctg tcagcagggg tgggtgtgtc aggcggaggc
      661 ctgacgagcc cggttgcgag cggcgcggcg cttcatggcg cggcgctcgt cctcgctgag
      721 accaccccag acgccggagt cctggccgga ctcgagcgcc cactgcagac actgctcgat
      781 caccgggcag cgacggcaga cggccttggc ttcctcgatc tgcagcagcg caggaccggt
      841 gttgccgatg gggaagaaga gctcggggtc ttcctcgcgg caaacggcgt tgtgacgcca
      901 gtccatggct gctacctctc cttggtatta cgtgcaagtt gcttgtgaat gtgaacgctt
      961 tcacgaatcc ctcaacaagt gaagggccga ccgccgagtc ttcacccggc gtggtcctgt
     1021 gtttgtagag gggttccggt gatcagtgga ggccggtgtt gcgggccgtc ccgatcgcca
     1081 cgtagagact cgcaaacctc agcggcggat acaacccctt ccggaaagtt ttttttgatt
     1141 cctcggtgtc gactaggtca cagccgtact tccatggggt ggatcctggc ctaaacgttc
     1201 gagtgaaagg actttcggcc gttccgctca cacaatcaca cgcagtgcac ggcgtacgcc
     1261 tgtgaacgtc acgctcgtac gcagccccag gtggtcaccg tccatctgca gaggcagagg
     1321 cgccttcgaa tgcaaggtga actggtccag atcgtgcagg gacagggcgt gcttcccgtg
     1381 tgggccccgc tcgggggacg aagtgagcaa ctgggtgcca taccgggcaa cagcggcggt
     1441 cgacaggcgg ctgagaccga gtacgtcgat gccggtgtcg aacgaggcct taggtgacgt
     1501 atacatcggg cgattaccga gatacgtcca cggggacgtg ttcgagacta tggcgacgac
     1561 gagatccccg acggggtccg cgccgggccg ttcgagcgtg atcgtgccgt gccggcggtt
     1621 cggctcgccg aggaactgcc ggatcacctg ccggacgtac agcgcgtgcg tcgacttctt
     1681 cccgcgctcg cgctgctgct cgacccggcc caccacgccc gcgtcgaagc cgagcccggc
     1741 gttgaacgtg aaccagcggg ccggcaccgc ctcgtcctcg gtgcccggcg tgcccgaggt
     1801 cagcccgagg ccgacgaccc gctcgctgcc ctcccggagc gcgtccagca gggcgccggt
     1861 ggcctcgacg gggtcgttgg gcaggcccag ggcgcgggcg aagacgttcg tggaaccgcc
     1921 ggggacgacg gcgagaccgg ggaggcggtc ggggtcggga ccggcgtgca ggaggccgtt
     1981 gacgacctcg ttgaccgtgc cgtcgccgcc gagggccacc accaggtcga tgtcgtcgct
     2041 ctccgccgcc tgtcggccaa gatcgcgggc gtggccgcgg tactcggtgg tgaccgcctc
     2101 cagcttcatc tcgctcgcca gcgcgtggat cagcacatca cgcctgcgtg cgcttgtggt
     2161 ggttgccgcc ggattgacca cgaggagtgc acgcatgcat ggcagcgtac ctactggggg
     2221 gtacagggcc cagcccgagg tagggatccg gtaagagacc gggcgtgagc ctgcacactc
     2281 gggggcgcgg ggcgccgcgg tgcgcccgcg caggagggct accctgctgg ggtgagcagt
     2341 cagcagaacc ccgccccgga caccgccgaa gccgccgcgg ccgcggagcc gcgcccgcgc
     2401 cggctgacgt acgcggcggc gctggccgcg ctggagggca ccgccctgct ggccggcggc
     2461 ctgtgggtgc tcgtcctcgg actgaccggc gccccggacg accggcagca ggccgtcacc
     2521 ctcgggatca ccctggccgt gctcgcgctg ctgccgctgc tcgccgcgcg cggtctgctg
     2581 ctgcggcgcg gctggagccg gggccccgcg gtgatcaccc aggtcatggc ccttccggtg
     2641 gcctacaacc tgctccgggc cgacagcatg gccatcccgg cgggcatcgc cctcgcggtg
     2701 gtcgccgtgg cggcgctggt gctcctcgtc aacggcgaga cgacccgggc cctcgggatc
     2761 aagggaccgg gccgggccga gtagcgcccg cggggagggc cgtcaccgag cgggcttccc
     2821 cgagcggggc ccgccggcgc ggcgctcact cctcgacgag gagcttctcc cgcagctggg
     2881 ccagtgtgcg ggccagcagc cgggagacgt gcatctgcga gatgccgacc tcctgcgcga
     2941 tctgcgactg ggtcatgttc ccgaagaaac gcagcagcag gatccgcttc tcgcgcggcg
     3001 gcaggtcctc cagcagcggc ttgagggact cgcggtactc cacgccctcc agcgcctcgt
     3061 cctcggcgcc cagggtgtcg gcgaccgccg gcgactcgtc gtccgtgtcg gggacgtcca
     3121 gggacagcgt ggagtacgcg ttcgcggact ccaggccctc caggacctcc tcctccgaga
     3181 tggcgagctt ctcggccagc tcgtggaccg tgggggagcg gccgtgcagc tgggacagct
     3241 cggccgtggc ggtggtcagc gacagccgca gctcctgcag ccggcgcggc acccggaccg
     3301 cccagccctt gtcgcggaag tggcgcttga tctcgccgac cacggtcgga gtggcgtacg
     3361 tggagaactc cacgccgcgc tcggggtcga accggtcgac ggacttgatc agaccgatcg
     3421 tggcgacctg ggtgaggtcg tccagcggtt cgccgcggtt gcggaaccgg cgcgccaggt
     3481 gctccacgag cggcaggtgc atacggacca gctggttacg cagctccgcg tactccgcgc
     3541 tgcccgcgtt cagcttgcgc agttccacga acatcgcccg cgccccgctg cggtcctggg
     3601 ggccgtgctg tacggcccgc acggcctccg cacccagcgc ctcctgctcg gcgtctcgct
     3661 catgctcgct catcgtcccg cccgtagccc ttccccgagc cgtggccccc gctcggccgg
     3721 gatcggcgcc gtcgcgtgcc tccggtggcg tgccctgtcc ggcaccgtca ccgtcgaccc
     3781 gcgcggagtc gtcctccggg tgcggcctgg cctgctcggg gatgccgtcg atgccgtccg
     3841 ccatgcgccg ggaaccgtcc cgggggcccg ccccggaggt ctcggcgctg ctcgaccagg
     3901 aggcaccccc gtccccggtc ggcagctcac gcgtgccgcg ctcttcgtcc cgcaccggcc
     3961 cgtccccgtt cctcacgccg gcccggggcc ggcgccgcgc tgtttgtaga ggctgatcga
     4021 caccgtcttg tcctcgtcca cggcggacga gaccttgccc gcgagggccg acagcacggt
     4081 ccaggcgaaa gtgtcccgcg agggggcgtg gccgtccgtg gtcggcgccg acacggtgac
     4141 ctccagcgag tcgtcgacga gccggaagac acagctgagc accgagccgg gcacggcctg
     4201 ctggagcagg atcgcgcagg cctcgtccac ggcgatgcgc aggtcctcga tctcgtccag
     4261 ggtgaagtcc aagcgggccg ccagaccggc cgtggccgtc cgcagcaccg acaggtaggc
     4321 acccgcagcc ggcagccgga cttccacgaa gtcctggttc gccgcgggtt cgcctgcgat
     4381 ctgggacacc ctcacctcca tggtggtaca agctttacgg ggccgaaggt tcgccccccg
     4441 gggtaacgcg tacgtggttc aagcggtgac gctatcgcgc tccgaacgtt tctgtcccgg
     4501 gaccccaacc ccctggcgtc actcacagta aagctgtgga tacgctccgt gtctagaggg
     4561 tttgcgggcc caaaagggaa gagcgcgcgc cgggttgacg tacccagacg tcagacgctc
     4621 gaaccgtcgt gcggcagccg ccgcatgcag tgtcacacga gaacgcggtc ggacgggaac
     4681 gctcagacga gcacgtggtc gacgaagcac caccgccagt cctcgccggg ctcgaaggtc
     4741 cgcatcaccg ggtgaccgga gttcgcgtgg tgctccgtcg cgtgccgccc cggcgaggag
     4801 tcgcagcagc cgacgtggcc acaggtcagg cacagccgca gctgtaccgg gtgcgtgccg
     4861 tcgcgcaggc actcgggaca ggtcttgtcg aggggctccg gttccgggtg cggcagcgcg
     4921 tcggcgtgcg tgcactgttt catgattgcc agattacgac gggtgtgcgg gtggccgcgc
     4981 ggaacacgag ggtgggcgag gaccatggac gtgatgcccc tgctgttgct ggtggcgggc
     5041 agcgccgcgg tggccgccgc ggcccggcgc acccccgcgc cggcgccgct gctgctggtc
     5101 gcggtcggac tggcggtctc gtacatcccc ggagtgccgt cctacaccct cgatccgcac
     5161 gtcgtcctgc cgctgctgct gcccccgctg ctgtacacgt ccgcgagcga cagctcctac
     5221 ctcgacctgc gggcccagct gcggccggtg gcgctgctct cggtcggcta cgtgctgttc
     5281 gcgaccgtcg tcgtcggctg ggccgcgtat ctgctggtcc ccgggctgtc gctgcccgcc
     5341 gcgctggtgc tgggcgcggt ggtggcgccg ccggacgcgg tggccgccac ggcggtcgcg
     5401 cgccgggtcg gcctgccctc ccggatcacc accatcctcc agggcgagtc cctgctgaac
     5461 gacgccacgg cgatcaccgc ctacaaggtg gccctcggcg ccgccgtcgg cgagggggcc
     5521 acctgggccg gcggcatcgg cgagttcgcg ctcgccgcgg tcggcggtgt cggcatcggg
     5581 ctcgtcctca tggcgcccct gcactggctg cgcacccacc tgaccgagcc cctgctgcag
     5641 aacacgctgt cgctgctgat cccgttcgtc gcctacggag tcgccgagca ggcgcacgcc
     5701 tccggggtgc tcgcggtcgt ggtcgtcgcc ctctatctcg gtcaccgcgc gtgggaggtc
     5761 gacttcgcca cccggctcca ggaggaggcg gtgtggaaga tggtcgcctt cgtcctggag
     5821 tccgcggtgt tcgccctgat cggcctccag ctgccgatcg tgctcaagcg gctcggcgag
     5881 tacgagggca gctccgccgt ctggtacgcg gtcgccgtct tcgtggtcgt ggtggtggcc
     5941 cggttcgtct gggtctaccc ggccaccttc ctgcccagac tgctgtccgc gcgcatcagg
     6001 gagcgcgagg agaaccccac ctggcggggc gcgatggtca cctcctgggc cgggatgcgc
     6061 ggtgtcgtct cgctggccat cgccttcgcc atcccgtcga ccatggccga cggcccccgc
     6121 aacctgatcc tcttcctgac cttcaccacc gtcatcggca ccctcgtcgt ccagggcgtg
     6181 acgctgccgc cgctgatccg gctgctgagg ttccccggcc gcgaccggca ggccgagacg
     6241 ctcgccgagg ccaacgccca ggcacaggcc tcgcgggccg ccgaggcccg gctcgacgaa
     6301 ctgctgtccg acgaacgcaa cgccctgccg ccgccgctcg ccgaccggct gcgcacggtc
     6361 ctggagcgcc gccgcaacgc cgtctgggaa cggctcggcc aggtcaaccc ggtcaccggc
     6421 gagtccgtgg acgacaccta ccgccggctg tcccgcgaga tgatcggcgc cgagcgcgag
     6481 gtcttcgtca ggctgcgcga cctgcgctac atcgacgacg agatgctgcg tgcgctgctg
     6541 cgacgcctgg acctggagga agcggcggcc taccgggagg ccggttagcg ttccggggcc
     6601 gccgtcccgg gctccgggaa cggccgtccc gtgacgacgg cggcgatcgt cgtcccgcgc
     6661 gcgaaggcgc cctcctgcgc cagagcggcg agcccgtaca gcaacttggc gacatagaga
     6721 cgttccacgg gcagcccgtg gcgctgctcg aagtcctgtg cgaacgcctc caggtccggg
     6781 gtcgtacgcg cgtacccccc gcagtggaag cggtcgtcca gggaccaggt gccgctgcgg
     6841 gcgccgaagg cacgttcctg cagggcccgt acgtcggctt ccaggaagcc gcccttcagc
     6901 accggtatac cgagcgcgcg ctgcccggcc gccagcccgg cggcgaggcc cgcgagggtg
     6961 ccgccggtgc cgcaggcgac cgcgacgacg tcggcgtggc cgcgcagttc cgcgccgagg
     7021 gcgagacagc cgcggaccgc ttcggcgttg ctgccgccct cgggtacgac gtacgcgtcc
     7081 tcggctccgg ccgcgcgcag gatccgggcc agggtctccg gctcggtctt gccgcggtat
     7141 gtcgatctgt cgacgaagtg cagccgcatg ccgtcggccg cgcaccgggc cagggacggg
     7201 ttgagcgggc ggccggccag ctcctggccg cggaccacgc ccgtggtcgg caggcccagc
     7261 agacggcccg cggcggcggt ggcccgcagg tggttggagt aggccccgcc gaaggtgacc
     7321 agcggacggc cggacgccgc cgcgaggttc ggcacgagct tgcgccactt gttgccgacg
     7381 aggtgggggt ggacgaggtc gtcgcgcttg agcagcagcc ggagccctcg gcgttcgaac
     7441 cggtcgtcac gtatgtcgtg caggggggag ggcaggcggg ggtcgagcag gtccgggctg
     7501 gtcaccgctt cattgtcgcc cggtgcgggg gcgggcgggg acggggccgc ccgcccgccc
     7561 cggcagcgga cggacgtacg gggcccgccc cacggcgcta atccttcagc cgctccctca
     7621 cccgctcccg cagccacgcc atcgagaagc cgcgcggatc caccttcccc ggctgccact
     7681 ccaggtggcc gatgaccgac cgctccgtcc agccgtggtg ccggcacact gccgcggcga
     7741 cccgttcgac cgcctccagc tgttccggtg gccacgggtc ctccccgtcg ccgaggttct
     7801 cgcactcgaa gccgtagaag tgccggttgc cgtcggtgtt cgcctcgttg tccggcggca
     7861 gccgcttctc ggcgatcacc gcgcgcagca cgtcgtcgtc cccgagcccg gcgtggttgg
     7921 cgcggccgta gccgacgagg tggaccctgc cgtccttggt gatcacaccg tggcacagcg
     7981 gccccggcag gtccgcggtg ccgtcgcggc acagctccac cgtccgggcg ctgccccggg
     8041 tcaccgtgtg gtggatcacc acaccgtgca ccggccccca gggccccttg tgattgcggt
     8101 tgtggtgctg ccagtcgccg acctcgacga ccgtgacgcc ctccgccctg agcgcgtcca
     8161 ggaatccgtt cgccgacatg ggtggggcca tgtccgactc cttcgtgccg tgcgtccggc
     8221 cgccggtcgc ggccggatgt ccggcctggt tctaccgaaa ccggacctcc cggacacatc
     8281 gttcggacgg tgtgcgagcc gatccggaca gcccgcgggc gccgcgcggg cggacgggat
     8341 ccctctttgt gcccggtgat ccgatgatcc attcccgctc tttcgggtaa tggcgcgccc
     8401 acgctgcgtg ctggaacgct cgaatgcgag accggtgccc gtgcgctcgg gcaccgggca
     8461 tacatgggga ggcatttctt tatgtcggta ggcgaagagg tccgcacgga tcagggcaag
     8521 ccgcagcagt ccctcgggac ggcggccgcg cggaacctgg ccaccaccac caagtccgtt
     8581 ccgcagatgc aggagatcag ctcccgctgg ctgctgcgca cgcttccctg ggtggacctc
     8641 cagggcggca cgtaccgggt gaaccggcgc ctcacgtacg ccgtcggcga cggccggatc
     8701 accttcgtga agaccggcaa ccaggtggag gtcgtcccga acgaactggg cgagctgccg
     8761 gccctgcggt cctacgagga cgaggaggtg ctgacggagc tggcccggcg ctgccggcag
     8821 cgcgacttcg cggccggtga ggtgatcgcc gacttcggca accaggcgga cgaggtctac
     8881 ctgctcgccc acggccgggt ggagaaggtc ggcacgggtc cctacggcga cgacgccgtc
     8941 ctcggggtcc tcgccgacgg cgcctacttc ggcgaccagg cgctgctcga cccggaggcg
     9001 atctgggagt acaccgtccg cgcggacacc tcgaccacgg tgctgatcct cagccgccag
     9061 gacttccagc aggtcgccga gcgctccgac tcgctgcgcg ctcacctgga acggctgcgc
     9121 tcgatccccg agcagcggac caacaggtac ggggagaagg aggtcgcgct ggcggccggc
     9181 cactccggcg agcccgacat cccgcacacc ttcgtggact acgagccgcg gccccgcgag
     9241 tacgaactca gcatcgccca gaccgtgttg cgcatccaca cgcgcgtggc cgacctgtac
     9301 aaccagccga tgaaccagac ggagcagcag ctgcggctca cggtcgaggc gctgaaggag
     9361 cgccaggagc acgagctggt caacaatccg gagttcggcc tgctcagcaa ctgcgagtac
     9421 gaccagcgga tccagccgca cgacggcgta cccggcccgg acgacctgga cgagctgctc
     9481 agccgccgcc ggggcaccaa gctgctcctg gcccacccgc gcgcgatcgc cgcgatcggc
     9541 cgggagctga acaagcgcgg gctggtcccg gagaccatcg acatcgccgg caaccgcatc
     9601 cccacctggc gcggggtccc gatctacccg tgcaacaaga tcccgatcag cgaggcccgt
     9661 acgacctcca tcatcgcgat gcgcaccggc gaggccgacc agggtgtcgt cggcctcagg
     9721 cagtccggca tcccggacga gatcgagccg agcctgtcgg tccggttcat ggggatcaac
     9781 gaacaggccg tcatcaagta cctggtgacg gcgtactact cggccgccgt cctggtgccc
     9841 gatgcgctcg gcgtgctgga gaacgtcgag atcggccggt ggaggtgacg tctgcgcacg
     9901 tggtggccgt gtccccggcc gccggcgcgg gtaggccctc ggggtacgcg tccggcgggg
     9961 ccggtggcgc cggcctccgt gggcctggcg agggggaggc atggccgagt tcatgaccga
    10021 gaccgaggag cgttcctccg gtgtgctgcg tcccggcacg gcggaggagc cgcgggagca
    10081 gaccggggac accggcggcc cgctcgacgc gcaggaggcg gcggtacagc tggagcgcac
    10141 ccgggcgctg gtcgacccgg agctgcgcgc ggccgtggag tcgctgcccg ctgccatgcg
    10201 ccggatcggg ctgtaccact tcggctggca gcacgccgac ggcagcccgg cggagggcaa
    10261 cgcgggcaag gcgatcaggc cggcgctggt gctggcggcc gccgccgcgc tcggcgggcc
    10321 ggcggcccgg acggcggccg tgcgggcggc agcggcggtc gaactggtcc acaacttcac
    10381 cctggtgcac gacgatgtga tggaccggga cagcacccgc cggcaccggc cgacggtctg
    10441 gaccgtgttc ggcgacaccg acgcgatcct cgccggcaac gccctccagg cgctggccct
    10501 gcggctgctc gccgaggatc cgcacccggc ctccgccccg gccgcggccc ggctcgcggc
    10561 ctgtgtcgtg gagctgtgcg agggccagca cgccgacacg cggctggagc agcgcgcacc
    10621 ggaggcggtc accctggagg aggtgctcgc catggccgag gcgaagaccg gtgccctgct
    10681 gggctgcgca tgcgccctcg gcgcgctgta cgcgggcgcg ggcgaggagg aggtggcggc
    10741 gctggacggc ttcggccgcc aggccgggct cgccttccag ctgatcgacg acgtcatcgg
    10801 catatggggg gacccgcggc acaccggcaa gccggccggc gcggatctcg ccgcccgcaa
    10861 gaagtccctg ccggtggtgg cggcgctgac ctccggcacc ccggcggcgg ccgaactcgc
    10921 cgcgctgtac gggaagccgt acccggggca ggaggcggcg gccggggaga tcgcgcgcac
    10981 ggcactggcg gtggagcggg ccggcggccg ggactgggcg caggccgagg cggccgaccg
    11041 gatggcccgg gccatgcagg agctggcccg cgcggtcccc gatcccgagg cggcgggcgg
    11101 gctgctcgcc ctggccgagt tcgtcacccg gcgcaccagc tgaggccgcc cgtcccggcg
    11161 gccgagaaga acccggagtc cccggcccgt gcggctcctg accccgcacg gaccccgggg
    11221 gctccggccc ggcggcgccc cgcacatccc cacagtgtgc ggggccccgc cctgtcccgg
    11281 acagaccggg gaagccgcgc accgtcggca acggcgcacc ggtgcggacg tacggcggga
    11341 aagcgccgag accgccgccg gcctaccctg agggcatgga cagcgacgca cgcgtctgtc
    11401 ccgcctgcgg acaggccgtc gagacggtcg tcaagcggca caagaccctg ggcgcctggg
    11461 tgccggtctg gggccccggc ccgtgccgca acccggactg cgcgaggtac gacgcgaccg
    11521 accagcccgc cgagccgggc aggcccgccc acgacgaccg gtccgccggt gcgccggccg
    11581 ggccgggcgg gagcggcccg gaggacccgt cggcggcggg cgccgggaac agcgccgtct
    11641 gagccgggcc gcccgtcacg gaggcggccg gggggacgcc gtagcgtggg cgcatgccga
    11701 aacttccgta catcctccac atcaccgagc gctccctgtg ggaggcggcg cgcgaacgcg
    11761 gtgcctatga gctctccacc cggggccgca ccctccagga ggagggcttc atccacttct
    11821 ccacccgtga ccagctcccg cgcgtcgccg gctttctcta cggcggctac gacggccccg
    11881 acgagctggt cgtcctcgtg gtggatccgg cccgggtcgg ggcgccggtg aagtacgagt
    11941 ccgtcgagcc gggcggggag gagttcccgc acgtgtacgg acccgtaccc gtcgaggcag
    12001 tggtggacgt ggagacctgg ggctgacgcg gacgcgggtc ccccgacggc tccgcggggc
    12061 tacccgacgc gggcgccggc cggcagcccg cccgtctccg ggtcgcggcc ggtcaggcag
    12121 tacgtgccgc cggccgggtc gcgcatcacc gtccagtggg cgccctcacg cacggccacg
    12181 gcgcccagct cctcgtgccg tacgcggacg gccgcgatgt ccgcacaggc caggtccagg
    12241 tgggcggagg ccgggcgctc ctcgtccagc cgctggagca gcagccgcac cgggaagccc
    12301 gtcggcggtc gcagcaccgt gaactccggc cgcgaccccg ccacttgctc ccacccggtc
    12361 agcccggccc agaacgcgga ctcggcgtcg taccgggacg gcgggatgtc gaggcacacc
    12421 tggtccaggc ggctgccgga caccaccggc ggccgtaccg cctccccctg ccagggcacg
    12481 gcgcagaaca actgcccggc gggagagcac agtacggccc agtcgccgtg gtccgccacg
    12541 aggccggcgc cgagtcgccg ggcgagcgcg accacctccc gtacgtcctc ggcgcacagg
    12601 tcgagatggg cgccgccgtc gcccccggtg accccctgga gcttcacgct cgggtccgtc
    12661 ccctcgggca gcagcgtcac gaactcgccg tcgtcgcccc ggaacgcgga cagccgggta
    12721 ccggtgacgg ccgtccagaa ggcgcaggcc tcgccgaggc gcgcggcggg gcggtcggcg
    12781 aaggcgtggg tccagcggat cgtcatccgg ggagtgtagg cgggccgtgc gaacgggagt
    12841 tcagccggcg gggcgttcga tgaagcggag ctggttgccc gcggggtccc ggaaggcgca
    12901 gtcgcggacc ccgtacggct ggtccatcgg ctcctggagg acgtcggcgc cggactcccg
    12961 cacccgctcg tacagcgcgt cgcagtcggg cgtggtgaag atgaccccgc gcagcaggcc
    13021 cttggcgagg agttcgttga gtgcctgctt gtccgtgggg gaggcgtccg ggctcgcgtc
    13081 cggcggctcc aggacgatct cgacgtccgg ctggagcggg gagcccaggg tcacccagcg
    13141 cattccctcg aagccgacgt cgttgcggat ctccaggccg agcacatcgc ggtagaaggc
    13201 gatggccttg tcgtggtcgt ccaccgcgag gaagcactgc gcgagtttca cgtccatgga
    13261 ctcaccctag ggccggcggg cgcgtcgcgc ctcagtacgg gcggcggcgc ggccgggtca
    13321 gccggcgggc cacacagggc gggatcaccg cgctctcctc gtggtcgcgg gcacggtagg
    13381 cgctcggcgt ctcgccgacc agctcggtga agcgggagct gaaggagccg agggaggtgc
    13441 agccgacggc gaggcacacc tcggtcacgc tcagatcgcc ccggcgcagc agcaccttgg
    13501 cccgctcgat gcgccgggtc atcaggtagc cgtacggcgt ctccccgaac gccttgcgga
    13561 agctgcgctg gaagtggccc ggggacatca gggcgtcacg ggccagctcg gtcatgtcga
    13621 gcggctcggc gtactcgcgg tccatgcggt cgcgcacccg ccgcagccgt ctcagatcct
    13681 ccagggcggt cacccgctca gcttcgcaca gcggcacacg ccggcacctc cgggttcggc
    13741 ggagcgcttc cctccgcatc acgcgggcgg tggcctcgac ggggcgtggg ggcgaaggcg
    13801 cccccacctc gatcccggcc gggccgaaca ggctgtgccc ggacgtgggc ctgaccggcg
    13861 gaccgggccg acgcgggctc cgccggccgg atcctggaac tgctgctcgc acgccccgaa
    13921 gccgacccga acgacggccg ccccggcccg gcgacggccg acctggcact cgactggctc
    13981 ggcacccacc ccaggcaccg caacgccgga ggcgtcctgc cggccacgct cggccgcccc
    14041 ggcctgacgc ctcggcagac gcaggcgttc gtggcgtcag cgcgcctccg gatcaccgcg
    14101 gccgccccgg ccgacgagcg cgtgccccga ctccggtgcc tgctgccacc gggggatggt
    14161 ggcggttcag cgggagcgcc acagcgcgat catggatttc caggacctgt tccgctggaa
    14221 gggcagctcg aagatccggg agaacagcca ggcgccgagc accgaagccg gaagggccac
    14281 gacgagcgtg aaccagaagg tgggcaggcc gggggagacg aagtgcgggg ccacgcggcg
    14341 gatgacggcc atgacgaccg gcaggtggat caggtagagg ctgtaggaga agccgccgag
    14401 actccgcagc ggccgcgtgg tcaggagccg tacgaggacg gcgggtctgc cggtggcgac
    14461 cgcggcgagc agcatcgcca tggcgggagc gatggccaga tccacccaga agtagtggtt
    14521 caccgtccag accgagccct ggacggcgcc cagcgccagc acgggtacgg cggccaggac
    14581 ggcgaaccat ggccagggca ggcgccgaac cctgtcggac gccacgacga ctcccgcgcc
    14641 cgccagcccc gcggcgaata ccggagcgag gtgtggagcg agccagttgt caccctccac
    14701 cgggttggcg ccggtggccg tcaggccccc gacgatcacc ggaagggcca cgcaggcgac
    14761 catgaccgcc gcgttcgact tccgccggat cagcaggaga agggggaaga ggagatacag
    14821 ctcggcctcc accccgatcg accagaacgc gccgttcggt gtcggggcgg tgaccatgtc
    14881 ctgggcgacg aggccgtaca cgagcaggga cgcgccggtg ggtggtccga agtgggaggc
    14941 cggcaccacg aacgaggaga tgaccaggct catggccagc gcggcccagt acggaggcag
    15001 gatgcgccag gcgcgccggc gcaggaaccg gacgaccccg tccgtgcgcc agccgtgacg
    15061 cgccggtgag atcgccaggg agaagccgga cagcaccagg aagaagacga cggcgagccg
    15121 cccgaacatc agcacgtcca gccatcctgg tgccgcactg tccgggtatc cggggaaggt
    15181 gtacagccag cagtggaaca ggacgacgta cagcgccgcc aggccgcgca gaccgtccag
    15241 cccctgcacg tgcggacggt cgtgcgctcc gccctcgccg ccgggggcgg ccgagcccgg
    15301 tgcgctgccg accgtccggg tcaaagccac cgaaatcgtc cccttctccg ggcgccgcgt
    15361 tcccccgcgc atgccgccgg cccgttaccc ccgacggcag accgggcagc acgacgccgc
    15421 ccgcagccac tggtacgcgg ctccctggcg cgcggttcaa cgcgttcggc gcccgcttct
    15481 cgccggagca ggcgcttcgc gcacaaggcc tcgtaccggg cgaagacgac cgcacccggc
    15541 ccgtcatgga cgccgtgctc ggcggactgc ggaccgggtg cggacaagga gacgctgcaa
    15601 tcggagaaac cgcaggtcag aaggcgtagg aaaatcaggc cttcttggtc tcccagaaga
    15661 tcttgtcgat ctgggcgatg tagtccagcg ccttctggcc cgtcgccggg tcggtggacg
    15721 ccttggcggc cgagagggcc ttcagggtgt cgttgaccag ctggtgcagc tccgggtact
    15781 tctcgaagtg cggggccttg aagtagtcgc tccagagcac ggagacgtgg tgcttggcca
    15841 gctccgcgcg ctgctccttg atgacggtgg cgcgcgcctg gaagtggggg tcgtcgttgg
    15901 cggccatctt ctcctggacg gccttcaccg actccgcctc gatgcgggcc tgggccgggt
    15961 cgtacacgcc gcagggcagg tcgcagtggg cgctgacctt gaccttgggg gcaaacaggc
    16021 gggaaagcat ggagcattcc ttcctcgtga tcgtcttctc aggtgcgaca ttactccctg
    16081 gggaaggcga tttctcgggt gccccctagg gcttaggaca aaagtccagg gtgagactga
    16141 gactggcgga ggaacggacc ggggaggtgc cggggatgcc ggagctgtcg caggagaccg
    16201 agcgggggag ggccgtggcg ctcttcgggc tggccgaggt gaccggcccg tcgatggtgc
    16261 ccacgctgca ccacggggat cggctgctgg tgcggtacgg gggtgtggtc cggcccgggg
    16321 acgtcgtggt cctgcgtcat ccgttccagc aggacctgct ggtggtcaag cgggccgtgc
    16381 agcggcgcga gggcggctgg tgggtgctcg gggacaaccc gtacgccggc ggggacagca
    16441 cggactacgg ggtcgtgccc gaggaactga tcctcggcac ggcctggttc cggtaccggc
    16501 cggtcaaggc cggtcagcgt tcgccgctcg cgctgctgcg ctgggcgctc tcggccgcga
    16561 ggccgctgct gcccgaccgg tcggcctcca ggcgcttgcg ggcccggtag gcggccacgt
    16621 tggcgcgggt cgcgcagcgg tccgaacagt agcgccggga gcggttggtg gaggtgtcca
    16681 ggtaggcgtt gcggcacggc ggcgcctggc acaggccgag gcggtccacg ccgtactcgg
    16741 tgaggtggaa ggccaggccc atcgccgcga tcgccgcgta gccggcggtg gcgttggacg
    16801 ggtggtcggc caggtgcatg tgccacaggg ggcggccgtc ctcgtcgcgg tggtcgtgcc
    16861 cggagatctg cgggctgacc gggaactcca gcaggagcga gttcagcagg tccacggcga
    16921 gggtctcgtc gcccttgtcg gcggcctcga acaccccgcg cagccgggcc cggaccgagc
    16981 ggaaccgcgt gacgtcggcg tcggtggcgc ggcgggccgc cgacgcgttc tcgccgaaca
    17041 ggtcgcggac ggcctcgacc gtgaccaggg tgtccctgcc ccggcccggt tcctcgctgt
    17101 tgacgaggcg gacggcgtaa tccgagtaat aggccagttc cacttgtagt ccttacggag
    17161 gcgcattatc gtcgtgtctg cggtcgggta acagccggtc gtgcttccag ggtattacgc
    17221 gaaccgaggg gagtcggtgc tcgatgacca caaccgccgg aaccgactgg gcggcctggc
    17281 aggagagctg ggaccggcag caggagtggt acatgccgga ccgcgaggaa cgcttccgga
    17341 tcatgctcga catggtcgag gcgctcgtcg gcaccgcccc gcgcgtgctc gacctcgcct
    17401 gcggcaccgg cagcatcacc gcccggctgc tgcgccggtt ccccggggcc accagcaccg
    17461 gcgtcgacct cgacccggca ctgctcgcca tcgcggacgg caccttcgcg ggcgacgacc
    17521 gcgtcaccct cgtcaccgcc gacctcacgg accccggctg gccggcgaag ctgccgtacg
    17581 actcctacga cgccgtcctg accgccacgg ccctccactg gctgcacagc gaacccctcg
    17641 cgaccctcta cggtcaggtc gcggggctgg tccgcgacgg cggtgtcttc atgaacgcgg
    17701 accacatgat cgacgacacc acgccccgga tcaacgcggc cgagcgcgcc cagcgccatg
    17761 cccgcatgga tcaggccaag cgggacggcg ccctggactg gaccgagtgg tggcagctgg
    17821 cggccgggga cccggtcctc gccgagccga ccgcccgccg cttcgagatc tacggcgaac
    17881 acgcggacgg ggacacgccg ccgcccgcct ggcacgcgcg cgtactgcgc gagaaggggt
    17941 tcgccgaggc caggccggtg tggtgctcac cctccgacac gctgctgctc gccctcaagt
    18001 aggggtgcgg gtgcagtggc ggcggtggtc gcctgggggg ccggcgtgcc gccctgcggg
    18061 gctcacggcc gcggtaccga ccgcgggatg tttcggcggc ggtgcggccg gattcgtcaa
    18121 gctgctcccg ccgtgcatga gcaaggtccg ggcaacttgc tgctgccgcc gaatcaggcc
    18181 acttcacagg cttcccgagc aaggactcgc agggctcgct gcaagtcgtc cccaaaagag
    18241 gcggtacgag gccccgcccc gtcctcgggc acctcagaag ttcctcaagt cgcgtgggtt
    18301 gctctgagat cgctgtcaat gtcttacctg cgtgatcatc ggcgcgcaaa ttcgctcggt
    18361 tgatcactta tgttggcgat caatcgccat ccgcgagcgc acttctgtca atcgaacggt
    18421 tgtccgacgg gcgcgaggag agagggttga agtgacagcc atacggaagc ttgcgcattc
    18481 ggcaggggtg ctggggctgg ttgtggcggg aagcgctctg gcgacgtctc ctgctgaggc
    18541 ctatagcaag acctgcaacg ccgatcagac ggcgtactac agcatctgct tcgacggcag
    18601 caacgacagc ttcatcgtcg acgacctgag gccggacggg gagcgcgcgg tcgtcaagtg
    18661 gtacgcctac gacggttcag gccgcgaagg tgagtgctcg gacgccaacg gttcgctcaa
    18721 cgggcccgtg gtctgcgact acgacttcaa ggagggcgtc aacaactacg tgtccttcat
    18781 gggcttcact cgtgacgggg cgagcgggcc caagcacaat gagtcctggg tgtacaacgg
    18841 atacatcacg ccgaggtagc ccttcgctgc atcgggacac cgtcgggggc ctgcgtctgg
    18901 ggaatggagc gcaggccccg ctcgggttca cagcaccttg gacaggaacg actgcgtccg
    18961 ttcgtgctgc gggttcgtca ggacgtcccg cgggtggccg gattccacca ccacaccgcc
    19021 gtccatgaac accaggctgt cgcccacctc gcgggcgaag cccatctcgt gggtgacgac
    19081 gaccatggtc ataccggact cggcgaggtc tcgcatgacg tccaggacgt caccgaccag
    19141 ctccgggtcc agggccgagg tcggctcgtc gaacagcatc agcttcggct ccatcgccag
    19201 ggcccgggcg atcgccacgc gctgctgctg gccgccggac agctgggagg ggtagtgccc
    19261 ggcccggtcg gccaggccca cgcgctccag cagctgcatg gcccgctccc gggcctgcgc
    19321 ccggctcacg cccttgacct gcaccggcgc ctccatgacg ttctccacgg ccgtcatgtg
    19381 cgggaacagg ttgaagcgct ggaagaccat gccgatgtcc cggcgcttca cggcgacctc
    19441 gcggtcgcgc agctcgtaca gcttctcgcc ctgctggcgg tagccgacca gctcgccgtc
    19501 gacgtacagc cgcccggcgt tgatcttctc caggtggttg atgcaccgca ggaaggtcga
    19561 cttgccggag ccggaggggc cgatgaggca gaacacctcg cccggcttca cctccaggtc
    19621 gatgcccttg agcacctcga cgtggccgaa ggacttgtgg acgccctccg ccttgaccat
    19681 cgggacggtg cccttcgacg gggtgtcctg cgtcttgctc agcttgtcgg tcatgccgtg
    19741 accttcctgc tcgacagggt cgtcaggtgg gccctgatct tctgccacgg ggtcggcggg
    19801 aggctgcggc tggaaccgcg ggcgtagtac cgctcgatgt agtactggcc gacgctcagc
    19861 accgaggtga ggatcaagta ccaggtggcg gcgaggaagt acatctccac cggggcgccg
    19921 gaggtctggc cgatgtcctg ggccacgcgg aacagctcgg agtactggac gaccgacacc
    19981 agcgaggttg tcttcagcat gttgatgacc tcgttgccgg tcggcggcac gatcacccgc
    20041 atggcttgcg ggatcacgat ccggaacagc gtcttgccgt ggctcatgcc cagcgcgtgg
    20101 gcggcctccg tctggccctc gtccacggcg agcaggccgg cacgacagat ctccgccatg
    20161 tatgcggcct cgttgaggcc gaggcccagc agggcggtca ggaacggggt catgaagtcc
    20221 gaccactcgt ccttgtagag cggccccagg ttgatgtact cgaagaccag gcccaggttg
    20281 aaccagacga cgagctgcac caggaccggt gtgccccgga agaaccagat gtagaaccag
    20341 gagatggagg acgtcaccgg gttcttcgac aggcgcatca ccgccaggac gatgcccccg
    20401 acgatgccga tcgccatgga caggatcgtc agcaggagcg tcttgctcat gccctccacg
    20461 acgcggtcgt cgaagaagta gtcggggatc gccccccagt tgatcgcgcc ctgggagaag
    20521 gcgtagacga tcgcggcgag gagcgcgagg gcgatgacgg cggaaacgta tcgtccgtag
    20581 tgccggaccg ggatggcctt gatcgcctcc ggtccggccg ggggagtgcc ctgctccccg
    20641 gccgtcttct ggatgtcagt cacgggtatt gcctctcagt ggccgcttgg tgccgcgggt
    20701 cacttgccgc cgttgatcac ggactccttg acggcgccgt cctgggcgcc ccacttctcg
    20761 aggatcttct ggtattcgcc gttcttgatg atcgcgttca tcgcggcctg gagggcgtcg
    20821 cgcagctgcg tctccttctt ggagaccgcg atgccgtacg gggccgcctc gacctggtcg
    20881 ccgacgacct cgaagtcctt gccgccgccg gaggtcttca ccgcgtacgc ggcgaccggg
    20941 aagtcggcgg acacggcgtc cgcgccgccc gagcgcagcc gggtctgggc ctgctggttg
    21001 tcgtcgaagg cctcgatggc gagcttcttg ccggacggac acttcttggc ctgctgcttg
    21061 gccaggtcct ccgaggtggt gccgcgctgg acggcgagct tcttgccgca gaggtcatcc
    21121 caggtggtga tccccttggt gtc
//
