LOCUS       NZ_CP071750            20612 bp    DNA     circular CON 16-APR-2024
DEFINITION  Burkholderia pseudomallei strain VBM21885 chromosome 2, complete
            sequence.
ACCESSION   NZ_CP071750
VERSION     NZ_CP071750.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei
  ORGANISM  Burkholderia pseudomallei
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3203152)
  AUTHORS   Balaji,V., Yamuna,B. and Monisha,P.
  TITLE     Complete genome of Burkholderia pseudomallei_VBM21885
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3203152)
  AUTHORS   Balaji,V., Yamuna,B. and Monisha,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2021) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore, Tamil Nadu 632004, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method :: CANU v. v.1.7; UNICYCLER HYBRID v. v.0.4.6
            Assembly Name                     :: VBM21885
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 39.4x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017378195.1-RS_2024_04_16
            Annotation Date                   :: 04/16/2024 08:15:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,514
            CDSs (total)                      :: 6,439
            Genes (coding)                    :: 6,286
            CDSs (with protein)               :: 6,286
            Genes (RNA)                       :: 75
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 153
            CDSs (without protein)            :: 153
            Pseudo Genes (ambiguous residues) :: 0 of 153
            Pseudo Genes (frameshifted)       :: 85 of 153
            Pseudo Genes (incomplete)         :: 98 of 153
            Pseudo Genes (internal stop)      :: 17 of 153
            Pseudo Genes (multiple problems)  :: 41 of 153
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2137931
            Orig. end                         :: 2158543
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071750.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Christian medical college.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="13"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20612
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10612](-)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10612)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     misc_feature    complement(125..140)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.78"
                     /tool="antismash"
     gene            487..765
                     /locus_tag="J3B47_RS27265"
                     /old_locus_tag="J3B47_27265"
     CDS             487..765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004528146.1"
                     /locus_tag="J3B47_RS27265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27265"
                     /product="hypothetical protein"
                     /protein_id="WP_004528146.1"
                     /transl_table=11
                     /translation="MGDEERAATNHDVCFADVDAARAASIGLARNDGDLLIRLVAMCRQ
                     TGGADRRGSSRGARLMVAREFARRELAARPEHRNVYPVHPIGLSAEA"
     gene            complement(874..1485)
                     /locus_tag="J3B47_RS27270"
                     /old_locus_tag="J3B47_27270"
     CDS             complement(874..1485)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204410.1"
                     /locus_tag="J3B47_RS27270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27270"
                     /product="LysE family translocator"
                     /protein_id="WP_004204410.1"
                     /transl_table=11
                     /translation="MSLSSLALFAAALLVAAGSPGPSIAALVARVLTNGVRDVLPFLAA
                     MWLGEVIWLTCAVAGLTALAHTFAFGFLVLKFAGIAYLVFLAWKMWFAPADEPSGQLPR
                     GQSPLRMFLTGIAVTLGNPKIMIFYVALLPTMVDLSRAGAVAWLELTLTLLVVLITVDC
                     AWAWLAARARKLLTSRRAMKAANRASAAAMAGAAVAIAMR"
     gene            1657..2136
                     /locus_tag="J3B47_RS27275"
                     /old_locus_tag="J3B47_27275"
     CDS             1657..2136
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968142.1"
                     /locus_tag="J3B47_RS27275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27275"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_045720239.1"
                     /transl_table=11
                     /translation="MAAIEAAAARRFDDIGMPHIASSPPTDLADLRERIDDDRALVAFD
                     AEGLRIVGFAIYRMLGASRLYLEEVDVAPEQAGRRIGSALIEAVAARARAAGARQVVLS
                     TFRHVPWNAPYYRRLGFVELDGNTLDAALTAIRATHVAHGLDESQRVFMARVVHE"
     gene            complement(2277..3338)
                     /locus_tag="J3B47_RS27280"
                     /old_locus_tag="J3B47_27280"
     CDS             complement(2277..3338)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015602739.1"
                     /locus_tag="J3B47_RS27280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27280"
                     /product="alkene reductase"
                     /protein_id="WP_207866345.1"
                     /transl_table=11
                     /translation="MPSLFDPLTIGDLTLANRIIMAPLTRARAGDTRTPNALMARYYAE
                     RASAGLIISEATSVTPQGVGYASTPGIWSPEQVDGWRLVTDAVHAAGGRIFLQLWHVGR
                     VSDPVFLDGALPVAPSAIAPGGHVSLVRPQRPYVTPRALEFDEIPGVVAAFRRGAENAR
                     AAGFDGVEVHGANGYLLDQFLQDSANRRTDAYGGSIENRARLLLEVVDAAIDVWSAARV
                     GVHLAPRGDAHTMGDSDPAATFGHVARELGRRRIAFLFARESFGGDAIGQQLKAAFGGP
                     FIVNENFTLDSAQAALDAGQADAVAWGKLFIANPDLPRRFKLNAPLNEPNAATFYAQGE
                     VGYTDYPALESAA"
     gene            complement(3388..3693)
                     /locus_tag="J3B47_RS27285"
                     /old_locus_tag="J3B47_27285"
     CDS             complement(3388..3693)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195494.1"
                     /locus_tag="J3B47_RS27285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27285"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_004195494.1"
                     /transl_table=11
                     /translation="MTFDADAIHKALASPVRRTILAWLKAPDKHFPASQAGPFPQGVCA
                     GQIDALCGLSQSTVSAHLATLERAGLVTSTRVGQWAFFKRNDAVIQAFLDSLQRGL"
     misc_feature    complement(3745..3763)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.92"
                     /tool="antismash"
     gene            complement(3776..4546)
                     /locus_tag="J3B47_RS27290"
                     /old_locus_tag="J3B47_27290"
     CDS             complement(3776..4546)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024189.4"
                     /locus_tag="J3B47_RS27290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27290"
                     /product="YXWGXW repeat-containing protein"
                     /protein_id="WP_225315724.1"
                     /transl_table=11
                     /translation="MTAVTGFVTIAGTRRVSVEPGRAIGSRRFQLTALKHHEPTPFSSQ
                     AVVRRRLARRPGLRPRLREAAAARAAVLAAPIVRRTTARRRSPVPRGRRIRAAPSGRLR
                     RFGASAAPHHRARGYVWTNGYWRWPGGRSVWIPGRWIAQRPGHRGSPAIGDNGQTCGSI
                     STDAGIACAASRTPFAAKAAKRIGEREAAAHRRRRTPRARFRRSDLSNAPARPRGPETN
                     QRRGKRAGTPAAARGFLPTAPTDAIASIAGFHRP"
     misc_feature    4532..4547
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(4809..4822)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.3"
                     /tool="antismash"
     misc_feature    4837..4846
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.58"
                     /tool="antismash"
     misc_feature    4840..4854
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.79"
                     /tool="antismash"
     gene            5023..6147
                     /gene="omp38"
                     /locus_tag="J3B47_RS27295"
                     /old_locus_tag="J3B47_27295"
     CDS             5023..6147
                     /codon_start=1
                     /gene="omp38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184655.1"
                     /locus_tag="J3B47_RS27295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27295"
                     /product="porin Omp38"
                     /protein_id="WP_004523988.1"
                     /transl_table=11
                     /translation="MNKTLIVAAVAASFATVAHAQSSVTLYGVLDAGITYQSNVATPSG
                     SGKSLWSVGAGVDQSRFGLRGSEDLGGGLKAIFTLESGFNIGNGRFNNGGGMFNRQAFV
                     GLSSNYGTVTLGRQYDATQDYLSPLSATGTWGGTYFAHPLNNDRLNTNGDVAVNNTVKF
                     TSANYAGLQFGGTYSFSNNSQFANNRAYSAGASYQFQGLKVGAAYSQANNAGANTTGAT
                     DPLTGFNIGGTNAASIQGRSRVYGAGASYAYGPLQGGLLWTQSRLDNLANGAPTIRADN
                     YEANVKYNLTPALGLGVAYTYTNAKANGESTHWNQVGVQADYALSKRTDVYAQAVYQRS
                     SKNANASIYNGDLSTPFSTSINQTAATVGLRHRF"
     gene            complement(6366..6764)
                     /locus_tag="J3B47_RS27300"
                     /old_locus_tag="J3B47_27300"
     CDS             complement(6366..6764)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195489.1"
                     /locus_tag="J3B47_RS27300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27300"
                     /product="GreA/GreB family elongation factor"
                     /protein_id="WP_004195489.1"
                     /transl_table=11
                     /translation="MRNRIYQLTELDVARLEKHAERNPRYQEMLDTLLERADIVEPNKI
                     QANVVTMNSQIKLLDETAGQDRAWTIVYPDAANFEQGRLNVFSPVGMALLGSRCGERVK
                     VTLPGGADATLKIVEIVYQPEASGDYAH"
     misc_feature    complement(7022..7038)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.83"
                     /tool="antismash"
     misc_feature    7029..7047
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.64"
                     /tool="antismash"
     misc_feature    complement(7030..7048)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.4"
                     /tool="antismash"
     misc_feature    complement(7032..7049)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.31"
                     /tool="antismash"
     misc_feature    7038..7051
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.81"
                     /tool="antismash"
     gene            7284..7625
                     /locus_tag="J3B47_RS27305"
                     /old_locus_tag="J3B47_27305"
     CDS             7284..7625
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900400.1"
                     /locus_tag="J3B47_RS27305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27305"
                     /product="DUF4148 domain-containing protein"
                     /protein_id="WP_004195487.1"
                     /transl_table=11
                     /translation="MKSFVYAAVAASILATPLASFAQADQQPPLTREQVRSELVQLEQN
                     GYKPEAGETQYPANVQAASQRMLPAQQTLTHADTSGYGVQPAGAAESGGRASRSPASPA
                     FGHSIYFGN"
     gene            complement(7834..8298)
                     /locus_tag="J3B47_RS27310"
                     /old_locus_tag="J3B47_27310"
     CDS             complement(7834..8298)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195485.1"
                     /locus_tag="J3B47_RS27310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27310"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_004195485.1"
                     /transl_table=11
                     /translation="MSLTVAQILRSKPDSGRTIHMVEKSDSVYNAIKLMAEKSIGALLV
                     MDGANIAGIVTERDYARKVVLLDRSSKATRVEEIMTSKVRYVEPTQTSDECMALMTEHR
                     MRHLPVLDDGKLVGLVSIGDLVKSVIADQQFTIDQLEHYIHGIPAAAHPQ"
     misc_feature    8329..8338
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            8475..9128
                     /gene="ribA"
                     /locus_tag="J3B47_RS27315"
                     /old_locus_tag="J3B47_27315"
     CDS             8475..9128
                     /EC_number="3.5.4.25"
                     /GO_function="GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ribA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195483.1"
                     /locus_tag="J3B47_RS27315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27315"
                     /product="GTP cyclohydrolase II"
                     /protein_id="WP_004195483.1"
                     /transl_table=11
                     /translation="MKSSHPDSPQPDDGAAPECVTLVATATLPTRYGTFTSYAFRVAGG
                     DAEHLALVMGDVAEQPSVLTRLHSECLTGDVFGSYRCDCGEQLDLSLRYIAAEGRGVLL
                     YLRGHEGRGIGLSNKIRAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRILKVTSV
                     RLMSNNPKKFDTLARHGIPVCERVALAVPVREENERYIRTKQLKFGHYYFDENE"
     gene            complement(9091..9912)
                     /locus_tag="J3B47_RS27320"
                     /old_locus_tag="J3B47_27320"
     CDS             complement(9091..9912)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004554929.1"
                     /locus_tag="J3B47_RS27320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27320"
                     /product="hypothetical protein"
                     /protein_id="WP_004531723.1"
                     /transl_table=11
                     /translation="MLPTFDAGETRIAVAFPSFAERLPLVRLGRQGLVFRARGAMPPVC
                     GLPRSATLYLDDEPLCTLRLVIREVERCDDGAHDLTMQPSAANGDALLWHALRTRCRHA
                     RAPLAPRAPDERPAPATQASARRRDTAPRADAARPESGAPRAAGTGVRMTRSAAFRLAD
                     RGDALFFADWLEYHFDELRALAQGLSPRLHLNELERDLAGDEVDVRFVYDIDGHADRRM
                     LTDCARQACDWIATEVRRRFDLPIAEQRFGARKPRRATRAIRFRRNNSGRT"
     gene            complement(10001..10612)
                     /gene="bspI1"
                     /locus_tag="J3B47_RS27325"
                     /old_locus_tag="J3B47_27325"
     CDS             complement(10001..10612)
                     /codon_start=1
                     /gene="bspI1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004523992.1"
                     /locus_tag="J3B47_RS27325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27325"
                     /product="N-acylhomoserine lactone synthase BspI1"
                     /protein_id="WP_004523992.1"
                     /sec_met_domain="Autoind_synth (E-value: 6.9e-26, bitscore:
                     88.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTFVHGDGRLPSDLAADLGLYRHRVFVEQLGWKLPSASEGFERD
                     QYDRDDTVYVFARDDDGEICGCARLLPTTRPYLLKELFPTLVAQDMPLPQSAAVWELSR
                     FAANAEDPAGGGNPAWAVRPMLAAVVECAARLGAKQLIGVTFLSMERLFRRIGVHAHRA
                     GPAQQIDGRMVVACWIDLDAQTLAALDLDPLLCAPPAEAA"
     misc_feature    10596..10609
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.13"
                     /tool="antismash"
     misc_feature    complement(10804..10817)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            complement(10837..11280)
                     /locus_tag="J3B47_RS27330"
                     /old_locus_tag="J3B47_27330"
     CDS             complement(10837..11280)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015603338.1"
                     /locus_tag="J3B47_RS27330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27330"
                     /product="DUF4902 domain-containing protein"
                     /protein_id="WP_004528152.1"
                     /transl_table=11
                     /translation="MNSPWLHRFRGSSTDGYVRLPMHAFAELRLVHVSSGIDSGLLVEL
                     RASDIDARIAGYTEWERPSSAGAAHLTVGWDWYIDGATGAFVIAWGDVRSNVMGVDGNG
                     LDIGMDPTSAALSRRLAQLNWPSAVTAAMLRRGDFAHAGPTLQ"
     gene            11354..12073
                     /gene="bpsR"
                     /locus_tag="J3B47_RS27335"
                     /old_locus_tag="J3B47_27335"
     CDS             11354..12073
                     /codon_start=1
                     /gene="bpsR"
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184923.1"
                     /locus_tag="J3B47_RS27335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27335"
                     /product="autoinducer-binding transcriptional regulator
                     BpsR"
                     /protein_id="WP_004184923.1"
                     /transl_table=11
                     /translation="MELRWQDAYLQFSAAENEQQLFQQIAAYTKRLGFEYCCYGIRVPL
                     PISKPVVAIFDTYPNGWMERYQEMNYLEVDPTVREGALSSNMIVWPEASASDATTLWSD
                     ARDHGLAVGVAQSSWASRGVFGLLTIARHTDRLTSAEINHLTLQANWLANMSHSLMSRF
                     LVPKLAPESGVALTHREREVLCWTGEGKTACEIGQILSISERTVNFHVNNILDKLGATN
                     KVQAVVKAIAMGLIDAP"
     gene            complement(12109..12825)
                     /locus_tag="J3B47_RS27340"
                     /old_locus_tag="J3B47_27340"
     CDS             complement(12109..12825)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897347.1"
                     /locus_tag="J3B47_RS27340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27340"
                     /product="MgtC/SapB family protein"
                     /protein_id="WP_004184903.1"
                     /transl_table=11
                     /translation="MTFEFALRLFTAFACGVAIGLERQIRQRTAGLRTITLVASGACLF
                     VTLGVLTGNGIPGVTQIAAYVVSGVGFLGGGVIMRDKGSIQGINTAATLWCSAAVGVLS
                     GAGHYLPALAGTGVVLLTNTLLRGVSQAINATPVSNADLVREYQITVICLASDEVHIRT
                     LLSNSMYAKPLSFQSLTSEDVPREADAPERIKVTATLKLHPKDQQKLEQIASRMSMEKS
                     ISSVSWTAKEAEPLME"
     gene            complement(13372..14577)
                     /locus_tag="J3B47_RS27345"
                     /old_locus_tag="J3B47_27345"
     CDS             complement(13372..14577)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900392.1"
                     /locus_tag="J3B47_RS27345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27345"
                     /product="metallophosphoesterase"
                     /protein_id="WP_004195471.1"
                     /transl_table=11
                     /translation="MRRVSSFLLRLTIIGVLLHVYVGFRLLPELASPAARYAGALWLVG
                     SCLLIPLGMLSRVFERQPLGDRVAWAGLLAMGFFSSLLVLTLARDVLLASLVTVDALAP
                     GAVSLAQWRIQTAAGVPLAALAVSVVGFVNARRRARVVDVAVPIDDLPAALDGFTIVQI
                     SDIHVGPTIKRGYVEAIVDAVNRLAPDLVAVTGDVVDGTVAQLAGHAAPLGRLRARHGA
                     FVVTGNHEYYSGADEWIAEFRRLGLDVLLNEHRTLDHGDGRLVIAGVTDYSAGHFDPAH
                     RSDPSAALAGAPADVRIRVLLAHQPRSATAAADAGFTLQLSGHTHGGQFFPWNFFVRLQ
                     QPFTAGLARLNGLWVYTSRGTGYWGPPKRLGAPSEITRVRLVRGEGNRTRAPASVTLNA
                     ER"
     gene            complement(14640..15224)
                     /locus_tag="J3B47_RS27350"
                     /old_locus_tag="J3B47_27350"
     CDS             complement(14640..15224)
                     /EC_number="1.1.1.298"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004532724.1"
                     /locus_tag="J3B47_RS27350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27350"
                     /product="malonic semialdehyde reductase"
                     /protein_id="WP_004195469.1"
                     /sec_met_domain="PF00881 (E-value: 3.8e-15, bitscore: 53.7,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSDSALDQIFRTARTHNAWQPKPVDDALLRELIDLVKWGPTSA
                     NSSPARFVFVKSPEAKAKLKPALSEGNLAKTMAAPVTVIVGMDMAFHDHLPKLFPHADA
                     RSWFAGNDALIEATAFRNASLQGAYLIVAARALGLDAGPMSGFDQAAVDAAFFAGTSIK
                     SNFLVNLGYGDAAGLFPRSPRFSFDEIARIE"
     gene            15357..15983
                     /locus_tag="J3B47_RS27355"
                     /old_locus_tag="J3B47_27355"
     CDS             15357..15983
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004528155.1"
                     /locus_tag="J3B47_RS27355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27355"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_004547422.1"
                     /transl_table=11
                     /translation="MDDLFDDLPRPDVDWHPDWLAPADADRFHARLVDEVAWRQDTMRT
                     PRGLLPLPRLTAWQGEPDALYVYSGIRNEPAPWTPAVLELKRRVEAASRARFNSVLLNR
                     YRNGFDSMGWHADDEPELGAEPVIASLSLGATRVFDLRHNETGVTHAYRLTNGSLLVMR
                     GRTQHAWRHRVPKEPAVRGERINLTFRWVSAPPAVERRARPRSRG"
     misc_feature    15359..15373
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.46"
                     /tool="antismash"
     gene            16070..17020
                     /locus_tag="J3B47_RS27360"
                     /old_locus_tag="J3B47_27360"
     CDS             16070..17020
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004528156.1"
                     /locus_tag="J3B47_RS27360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27360"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_004528156.1"
                     /transl_table=11
                     /translation="MAKTTTTAAGRPAADAASAKSRRAAAGARPELDAADDEAAGGASS
                     YLVPGLERGLRILSEFSAREPVLSAPELSKRIGIPRTTTFRLLQTLEALGFIERANGDR
                     HFRLGIGVLRLGFEYLNSLELTDLGAPVLERLRDAAGLSTHLLIRDRRDVVFVAKAQSN
                     APMFGSVKVHVGTRLPAHATVHGHVLMGDLTRDAMRQLYPEKRLEAFTEHTPATVDELY
                     ERVRHYARLGYALSEGAFESGISAVTAPVRDHSGSIVAAITATVPRSEIGAVDEKERLV
                     ELVCGAAVDLSQRLNYRPLDSDPTVAHARHKVALL"
     gene            complement(17337..18425)
                     /locus_tag="J3B47_RS27365"
                     /old_locus_tag="J3B47_27365"
     CDS             complement(17337..18425)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009939921.1"
                     /locus_tag="J3B47_RS27365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27365"
                     /product="porin"
                     /protein_id="WP_004184835.1"
                     /transl_table=11
                     /translation="MVKHAAATLLGALAVAGAWAQSSVTLYGSLDAGVAYVNNVGGGAK
                     WSMIQGNTQPDRWGLKGVEDLGGGLKAIFQLENGFYTNNGQMAAAGTMWNRQAFVGLNS
                     DRLGALTLGHQTPFNFDWLDPLSSAFLAQSWYAFHPGNLDQLADTSTVPFNNSVKYRSP
                     VFAGFTVGAMLGFGNTTNFSTGRTMSFGVNYANGPFKAAAVYSNEHDQAFPMATVGGIA
                     GPGGTFQGMPVASYVAKKAQNMGAGLSYRFGPLLVHGLYTRVKLQANGHSDTFQSYDAG
                     ANYQSSPFNVIAGGAATSTLAGRRWSQFELGDTYSLSKRTQLYVNVLYEHASGNAKAAF
                     FTAGASSTANQVIVLTGIHHSF"
     misc_feature    complement(18399..18401)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18758..18771)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.91"
                     /tool="antismash"
     misc_feature    complement(18858..18872)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.26"
                     /tool="antismash"
     gene            18860..19177
                     /locus_tag="J3B47_RS27370"
                     /old_locus_tag="J3B47_27370"
     CDS             18860..19177
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006396774.1"
                     /locus_tag="J3B47_RS27370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27370"
                     /product="non-heme iron oxygenase ferredoxin subunit"
                     /protein_id="WP_004184916.1"
                     /transl_table=11
                     /translation="MSEQWVCAGHAGALSEDSPIEFKRTDGVEIGIYRVGDDVYALENV
                     CPHAYALLTQGFVDEGTVECPLHEAVFDIKTGQCLKGPGGRALKTYAVRLAGEEIQIKV
                     E"
     gene            19179..19490
                     /locus_tag="J3B47_RS27375"
                     /old_locus_tag="J3B47_27375"
     CDS             19179..19490
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184841.1"
                     /locus_tag="J3B47_RS27375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27375"
                     /product="recombinase-like helix-turn-helix
                     domain-containing protein"
                     /protein_id="WP_004184841.1"
                     /transl_table=11
                     /translation="MNETTVNFNPLLMPWRAPQPNNVAGKGQIEIPGRMPNLVWQTRKA
                     EPTQYENDLGDALERVFESGATELAEVVAGLNRIGFRAPDGAEWTAERFCAELAALAE"
     gene            19525..20592
                     /locus_tag="J3B47_RS27380"
                     /old_locus_tag="J3B47_27380"
     CDS             19525..20592
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195457.1"
                     /locus_tag="J3B47_RS27380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_27380"
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_004195457.1"
                     /transl_table=11
                     /translation="MTSSDQTNSGADPVRAYLDRGIRNYWYPVAPSWQVSSAPVGITRL
                     SEQIVLWRDREGNVHALEDRCPHRGARLSLGWNLGDRVACWYHGVEVNGGGTVTKVPAV
                     SNCPLEGQACVKSYPVEERAGAIFLWFGDDAHREPAPLVLPDELVAPEYAQFVCVSNWT
                     CNYQYAIDNVMDPMHGAYLHATSHSMAEGDKQADMRVRRTETGLMFEKVNQRDVNFDWV
                     ELGETGCIWLRLAIPYQRKFGPGGSFGIVGFATPIDDEHCQVYFWRTRKVAGWQRDVWR
                     FLYRNRLEGLHWAVLEQDRYVLESMAPNARDHEYLYQHDIGVTRVRRMLRQRAQEHLAA
                     LDAHRAAQADAAERA"
ORIGIN
        1 gaactacagt ttgtcgaaac ggacggcgct gtatgcggtc gcgatcggac agatcgcatc
       61 ggggcgcggg ctcggcagcg acgcgaacgg cgatcccgtg aactacgcgc agattcccgt
      121 attggcgaac agcaattcga accggcagct cgcgatgatg gcgggggtaa aggtggattt
      181 ctgacgggcg gcgtgtttgg cactgcttgg gatgccgcct tggcgcggtg tgtttcgctt
      241 ggcgaagcag tcttgtcgcg tggcggcgtg cgcgtgcgac gccagtggag gccgacgttc
      301 tcgccgcacg gtcgtcgcga gcgatgacgg atcgcgcaat ggtcggcaga gcggccatga
      361 acgaggcgac tttggcgccg ggatgcgcgg gcttgcgcga ggcgcgggcg gttcgcgtcg
      421 cgtgccgata cgggcggcac gcatgggatg cgcgccgatc attggccgcg agcgtcgaaa
      481 ccgtggatgg gggatgagga gcgcgcggcg acgaatcacg atgtctgttt cgcggatgtc
      541 gacgcggcgc gggccgcgtc gatcggcttg gcgcggaacg acggcgatct gctgatcagg
      601 cttgtcgcga tgtgcaggca aaccggcggc gcggatcggc gcgggtcgag ccggggcgcg
      661 cgtctgatgg tggcgcggga atttgcccgt cgcgaactag cggctcgccc ggagcatcgg
      721 aatgtatatc ctgtacaccc gattgggctc tcggccgagg cgtgaaaaaa cttgcccatg
      781 caggcgctgg gtacgcgtcg ccacgcgcgt tttgacgtgc gtcggccggt gcggctggcc
      841 acgcgtggtc gcgccgtgtt ggcgcgcggc cggtcagcgc atcgcgatcg cgacggcggc
      901 gcccgccatc gcggccgcgc tcgcgcgatt cgccgccttc atcgcgcggc ggctcgtcag
      961 cagcttgcgg gcgcgcgccg cgagccatgc ccatgcgcag tcgaccgtga tcaacacgac
     1021 gagcagcgtc aacgtcaatt cgagccatgc gacggcccct gcgcgagaca gatccaccat
     1081 cgtcggcagc agcgcgacat agaagatcat gattttcggg ttgccgagcg tgaccgcgat
     1141 gcccgtcaga aacatgcgca acggcgactg tccgcgcggg agctggccgg acggctcatc
     1201 ggcgggcgcg aaccacatct tccacgcgag aaacacgagg taggcgatgc ccgcgaactt
     1261 cagcacgaga aagccgaatg cgaacgtgtg cgcgagcgcc gtgagcccgg ctaccgcgca
     1321 ggtcagccag atcacttcgc cgagccacat cgccgcgagg aacggcaaca cgtcgcgcac
     1381 tccgttggtc agcacgcgcg cgaccagcgc ggcgatgctc gggccgggcg agccggcggc
     1441 gaccagcagg gcggcggcga agagggcgag gctggatagt gacatgctca aactcccgag
     1501 gcgatgcgat gacgatcggt tcgtcaacga tcgattatag tgacggctgc tcgcacccga
     1561 tcgaccatgc gccattcacc agtgactgca cgccgctcag ccgctcgacc ctgtccaatc
     1621 ggcatccgcg ccgcgcgcgc cgacgaagcg ccgctgatgg ccgccatcga agccgccgcc
     1681 gcgcgccgtt tcgacgacat cggcatgccg cacatcgcgt cgagcccgcc gaccgatctc
     1741 gccgatctgc gcgagcggat cgacgacgat cgcgcgctcg tcgccttcga tgccgagggg
     1801 ctgcgcatcg tcggttttgc gatctacagg atgctcggcg cgtcgcgcct ctatctcgaa
     1861 gaggtcgatg tcgcgcccga gcaggcggga cggcggatcg gatccgcgct gatcgaggcc
     1921 gtcgcggcgc gcgctcgcgc ggcgggtgcg cggcaggtcg tgctgtcgac gtttcggcat
     1981 gtgccgtgga acgcgccgta ttaccgccga ctcggcttcg tcgaactcga cggcaacacg
     2041 ctcgacgccg cattgacggc gatacgcgcg acacacgtcg cgcacgggct cgacgaatcg
     2101 caacgcgtgt tcatggcgcg cgtggtccac gaatagcgtc acagccggcg ctggcatgcg
     2161 atctcgcatg ttgaacgatg acggccgatc gccgatcgcc aatcgcccga agcgcacggc
     2221 tcaagccgcg gaaaccaaac cgtcccaaac gccggcgccc gggtccggac acctcctcac
     2281 gccgcgcttt ccagcgccgg atagtccgta tagcctactt cgccttgcgc atagaacgta
     2341 gcggcattcg gctcgttgag cggcgcattc agcttgaagc ggcgcggcag gtccggattc
     2401 gcgataaaaa gcttgcccca cgcgaccgcg tccgcctgtc ccgcgtcgag cgccgcctgc
     2461 gcgctgtcga gcgtgaaatt ctcgttcacg atgaatggcc cgccgaacgc cgccttcaat
     2521 tgctggccga tggcgtcgcc gccgaacgat tcgcgtgcga acaggaacgc gatgcggcgg
     2581 cggccgagtt cgcgcgcgac gtggccgaac gtagccgcgg ggtccgaatc gcccatcgtg
     2641 tgcgcatcgc cgcgcggcgc gagatgcacg ccgacgcgcg ccgcgctcca gacgtcgatc
     2701 gccgcgtcga ccacctcgag caacaggcgc gcgcggttct cgatcgagcc gccgtacgcg
     2761 tcggtgcggc ggttcgcgct gtcctgcagg aattgatcga gcagatagcc gttcgcgccg
     2821 tgtacctcga cgccgtcgaa gccggccgcg cgcgcgtttt ccgcgccgcg gcggaacgcg
     2881 gcgacgacgc ccggaatctc gtcgaactcg agcgcgcgcg gcgtcacgta cggccgctgc
     2941 gggcgcacga ggctcacgtg gccgccgggg gcgatcgcgc tcggcgcgac gggcagcgcg
     3001 ccgtcgagga acaccggatc cgacacgcgg ccgacgtgcc agagctgcag gaagatgcgg
     3061 ccgccggccg cgtggaccgc gtctgtcacg agtcgccacc cgtcgacctg ttcgggcgac
     3121 cagatgcccg gcgtgcttgc gtaaccgacg ccttgcggcg tgaccgacgt cgcctcgctg
     3181 atgatgagcc ccgcggatgc gcgctccgcg tagtagcgcg ccatcagcgc gttgggcgtg
     3241 cgcgtgtcgc cggcgcgggc gcgcgtgagc ggcgccatga tgatgcggtt cgcaagtgtg
     3301 aggtcgccga tggtcagcgg atcgaacaga gaaggcatga gggaacctct tcgagtgtgg
     3361 ctaagccctt gcggcgggtg ggcggaatca aaggccgcgc tgcagcgaat cgagaaacgc
     3421 ctggatcacc gcgtcgttgc gcttgaaaaa cgcccattgg ccgacgcggg tcgacgtgac
     3481 gagcccggcg cgctcgagcg tcgcgaggtg cgcggacacg gtcgactgcg acaatccgca
     3541 cagcgcgtcg atctggcccg cgcagacgcc ttgcggaaac ggccccgctt gcgatgcggg
     3601 gaagtgcttg tcgggcgcct tgagccacgc gaggatcgtg cggcgcacgg ggctcgcaag
     3661 cgctttgtga atggcgtcgg catcaaaggt catgggcggc gcggtgaaat cgcgaatcgt
     3721 cgtttgccga agcttaaatc ggccgatgac gatataaaca gcaacactct attgactagg
     3781 ggcgatggaa tccggcgatc gaggcgatag cgtcagtcgg cgccgtcggg aggaatccgc
     3841 gggccgccgc cggcgtgccc gcgcgtttgc cgcgtcgctg gttcgtctcc ggccctcgcg
     3901 ggcgcgcagg ggcgttcgac aaatcgctgc gccgaaaacg ggcgcgcggt gttcgtcggc
     3961 ggcgatgcgc cgccgcctcg cgttccccga tgcgtttcgc ggctttcgcg gcaaacggcg
     4021 tgcggctcgc cgcgcacgca attccagcgt ccgtcgatat cgagccgcac gtctgcccgt
     4081 tgtcgccaat agccggagat ccgcgatgcc cggggcgctg cgcgatccag cggcccggaa
     4141 tccatacgga tcggccgccg ggccagcgcc agtagccgtt cgtccagaca tagccgcggg
     4201 cgcggtggtg cggggcggcg ctcgcgccga agcggcggag gcggccgctc ggggcggccc
     4261 ggatacggcg gccgcgcggg acggggctgc gccggcgcgc ggtggtccgg cgaacgatcg
     4321 gggcggcgag gaccgcggcc cgggcggctg ctgcttcgcg gagccgtggc cgaagcccag
     4381 gccggcgagc gaggcgccga cgaacgacag cctgcgacga aaatggcgtc ggttcatggt
     4441 gcttcaaagc ggtgagctgg aagcggcgcg agccgatcgc gcgcccaggt tcgacgctaa
     4501 cgcgccgcgt gccggctatc gttacgaatc ctgtaacggc cgtcacggcg cgccgcagcc
     4561 gggcgggaca cgggcattgc aggaattcat ggtagctgtt cggcgatagt cttccatttt
     4621 catgacgcag atccgggtcg gatcggtaaa aaatgccgag tccgccgcgt ttgcgcggaa
     4681 ctgcttgttg tttatacgca accgtcaaga cgctgacaca gaagaatgct cgtggcgacc
     4741 gtgccaaaaa gccggtgtca agaggccaaa aatgtctatc aaaacaaata cttataagag
     4801 gatcgcattt ctattatttc tagttctgga aaagcttatt tctttattcg cgaatggcgg
     4861 ccctagggta cacccctaaa ctcacggttc ccataacggg caaccatccg ggcgcggcca
     4921 tgcaggtagt ttcgcaagcc gatatggcgc ttccgggcgg ttgcagaccg tttatcgaaa
     4981 cgaggtcgca aggcctacct tttttaaaag ggagctccac gcatgaacaa gactctgatt
     5041 gttgcagcag ttgctgcatc gttcgcaacc gtcgcgcacg cgcaaagcag cgtcacgctg
     5101 tacggtgtgc tcgacgcggg catcacgtac caaagcaacg tcgcgacgcc gtcgggctcg
     5161 ggcaagtcgc tgtggtcggt cggcgccggc gtcgaccaaa gccgtttcgg tctgcgcggc
     5221 tcggaagacc tgggtggcgg cctgaaggcg atcttcacgt tggaaagcgg cttcaacatc
     5281 ggtaacggcc gcttcaacaa cggtggcggc atgttcaacc gtcaagcgtt cgtcggtctg
     5341 tcgagcaact acggcaccgt cacgctgggc cgtcagtacg acgcaaccca agactacctg
     5401 tcgccgctgt cggcaacggg cacctggggc ggcacgtact tcgcgcaccc gctcaacaac
     5461 gaccgcctga acacgaacgg cgacgtcgcg gtgaacaaca cggtcaagtt cacgagcgcg
     5521 aactacgccg gcctgcaatt cggcggcacg tactcgttct cgaacaactc gcaattcgcg
     5581 aacaaccgtg catacagcgc gggcgcttcg taccagttcc aaggcctgaa ggtcggtgcg
     5641 gcgtactcgc aagctaacaa cgctggcgcg aacaccacgg gcgcaacgga tccgctgacc
     5701 ggcttcaaca tcggcggcac gaacgcagca agcatccaag gccgctcgcg cgtgtacggc
     5761 gccggtgcaa gctacgctta cggcccgctg caaggcggcc tgctctggac gcaatcgcgt
     5821 ctcgacaacc tggcaaacgg cgcgccgacc atccgtgccg acaactacga agcaaacgtg
     5881 aagtacaacc tgacgccggc tctgggtctg ggtgttgctt acacgtacac gaacgcgaag
     5941 gcgaacggcg aaagcactca ctggaaccaa gttggcgtcc aggccgacta cgcgctgtcg
     6001 aagcgcaccg acgtgtacgc acaagccgtg taccagcgtt cgtcgaagaa cgcgaatgcg
     6061 tcgatctaca acggcgacct cagcacgccg ttcagcacgt cgatcaacca aaccgcagcg
     6121 acggttggtc tgcgtcaccg cttctaagct tgacggctgg ctcgtccagt ctcgaaaagg
     6181 cgccttcggg cgcctttttt tatgcgcgat gcgaacgcga tgcgcgccgc gcggaaacaa
     6241 aaaagcgagg cctgcgcatg catcctcgct ttggcgtggc ggccgttgcc gattcgtcgc
     6301 cgctcacgcg ggccggcgat cgttcggcgg ccgcgccgca ttcgccgatc cgtcgtcgtg
     6361 cggccttagt gcgcgtagtc gccgctcgct tccggttgat agacgatctc gacgatcttc
     6421 agcgtcgcgt ccgcgccgcc cggcagcgtc actttgaccc gctcgccgca gcgcgagccg
     6481 agaagcgcca tgccgaccgg cgaaaacacg ttcaatcggc cttgctcgaa attggccgcg
     6541 tccggataga cgatggtcca ggccctgtcc tggccggctg tctcgtcgag cagcttgatc
     6601 tgcgagttca tcgtgacgac gtttgcctga atcttgttcg gctcgacgat atcggcgcgc
     6661 tcgagcagcg tgtcgagcat ttcctgatag cgcgggttgc gttccgcatg cttttcgagg
     6721 cgtgcgacat cgagttcggt gagttggtaa atcctgtttc tcatgacagt ctccaaatga
     6781 tcggcttggg tggcgtggcc aacccgggat cgcccggagc ctgactgacg cggctccggg
     6841 atggaggctg ccgtcagatc aagcgccggg ccgcggcgag cggcgctgca agcgtgcttc
     6901 gaaggagggg acgcatcgcc gccgcggccc cggccgcgcg cgtaccgcgc gtgcggtgcg
     6961 caagaaaggc gtgggaggtc ggcgtgcgca tgagcgaggc gatcaaacga aaggcgaatg
     7021 acggttcaaa ctttacaaat atacaacaaa acgaccgttc agacagccga cagacggctg
     7081 cgcgaagcgt tcctccattg ttgccgagat ggtgctttta accggctttc tgtccgacta
     7141 cagtcggcta tttttgtcat tggtgcaacg ctgtatgttc aaagtagggg tttccccttg
     7201 ttgttccggt gactagactg aaatcaatcg cttccggcaa gggtgccggg agcgacgcaa
     7261 atacaacatt ccggaggtca atcatgaaat cgttcgtcta tgcagccgtt gccgcttcga
     7321 tcctcgccac gccgcttgca tcgttcgcgc aggccgacca gcagccgccg ttgacccgcg
     7381 agcaggtgag gtccgagctg gtccagctcg aacagaacgg ctacaagccc gaagcgggcg
     7441 agacccagta cccggcgaac gtgcaggctg cgtcgcaacg gatgctgcct gcgcagcaga
     7501 cgctcacgca tgccgatacg agcggctatg gcgttcagcc ggccggtgcg gcggaatccg
     7561 gcggccgcgc gagccgatcg ccggcttcgc cggcattcgg tcattcgatc tacttcggta
     7621 actgattgat cgaatcgagc ggtcagctcc agtgtgagcc cggcatcgcc aggcgcccgt
     7681 cagcccacgc caagaggtcg attctcaaac cgcgagcccg tgcgatgcgt cgggctcgcg
     7741 ggccaggagc cgaacctccg tcgccgcatt tcggcggctt tgcccagacg cgatgcgttt
     7801 gggcattttt tgatgggcgt tgcggcgcgc ggctcattgc ggatgcgcgg cggccggtat
     7861 tccgtggatg taatgctcca attgatcgat cgtgaactgt tgatcggcga tcacgctctt
     7921 cacgagatcg ccgatcgaca cgaggccgac gagcttgccg tcgtcgagca cgggcaagtg
     7981 gcgcatccgg tgttccgtca tcagggccat gcattcgtcg ctcgtttgcg tcggttcgac
     8041 gtagcggact ttcgacgtca tgatttcctc gacgcgtgtc gctttcgacg aacggtcgag
     8101 gagtaccacc ttgcgcgcgt aatcgcgttc cgtcacgatg ccggcaatgt tcgcgccgtc
     8161 catcacgagc agcgcgccga tgcttttctc ggccatcagc ttgatcgcgt tgtagacgga
     8221 atcggacttt tcgaccatgt gaatcgtgcg ccccgaatcg ggcttcgacc tgagaatctg
     8281 tgcgacggtg aggctcatac gctgtctccc ttggctgggc gattcacgga aggcggcgcg
     8341 cagccgccgc gtcgggtgaa gaatccagta tagatcggcg tccgcgggcg ggtgcgtcca
     8401 gtgcgcagat tagcggtaaa ctccgtgcac tcgccatcca gaacatacct taatcctttc
     8461 gtttgatgca ttccatgaag tcttcgcatc ctgactcgcc gcagccggac gacggcgccg
     8521 cgcccgagtg cgtgacgctc gtcgccaccg cgacgcttcc tacccgctac ggcacgttca
     8581 cgtcgtatgc gtttcgcgtg gcgggcggcg atgccgagca cctcgcgctc gtgatgggcg
     8641 acgtcgccga gcagccgtcg gtgctgacgc ggcttcattc cgagtgcctg acgggcgacg
     8701 tgttcggctc gtatcgatgc gattgcggcg agcagctcga tctctcgctg cgctacatcg
     8761 cggccgaagg gcgcggcgta ttgctgtatc tgcgcggcca cgaaggccgc gggatcggcc
     8821 tgagcaacaa gatccgcgcg tatgcgctgc aggagcaggg gcgcgacacc gtcgaggcga
     8881 acctcgacct cgggctaccc gacgacgcgc gcgaatacga ttccgccgcc gcgatcctgc
     8941 gcatcctgaa agtcacgtcc gtgcgactga tgagcaataa tccgaagaag ttcgacacgc
     9001 tcgcgcggca cggtatcccg gtctgcgagc gcgtcgcgct cgccgtgccg gtgcgcgagg
     9061 agaacgagcg ctatatccgc acgaagcagc tcaagttcgg ccactattat ttcgacgaaa
     9121 acgaatagcg cgcgtcgcgc ggcgcggctt gcgcgcgccg aagcgctgct cggcgatcgg
     9181 cagatcgaag cggcggcgca cttcggtcgc gatccagtcg caggcctgcc gtgcgcaatc
     9241 ggtgagcatc cggcggtccg catggccgtc gatgtcataa acgaagcgca catcgacctc
     9301 gtctcccgcc aggtcccgtt cgagttcatt caggtgcagc cgcggcgaca ggccttgcgc
     9361 gagcgcgcgc aattcgtcga agtgatattc gagccaatcg gcgaaaaaga gcgcgtcgcc
     9421 gcgatccgcg agacggaacg ccgcgctgcg cgtcatgcgc acgccggtgc ccgccgcgcg
     9481 cggtgcgccc gattcggggc gcgccgcgtc ggcgcgcggt gcggtatcgc gccggcgggc
     9541 cgacgcctgc gttgccggtg ccgggcgctc gtccggcgcg cgtggtgcga gcggcgcgcg
     9601 cgcgtgtcgg catcgcgtgc gcagcgcgtg ccagagcagc gcgtcgccgt tcgcggccga
     9661 cggctgcatc gtcagatcgt gcgcgccgtc gtcgcaacgc tcgacttcgc gtatcacgag
     9721 ccgcagcgtg cagagcggct cgtcgtcgag atacagggtc gcggagcgcg gcaatccgca
     9781 gacgggcggc atcgcgccgc gcgcgcgaaa cacgagtccc tgtctgccga gccgcacgag
     9841 cggcaggcgt tcggcgaacg acgggaacgc gacggcgatg cgggtttcgc cggcatcgaa
     9901 cgtagggagc atcgcgcgaa ataccgttga atggtccacg gtgtagaggt ctccttgaat
     9961 gacgaacggc gcggccccga agcggggcga ccgggcgcgc tcaggcggct tcggcgggcg
    10021 gcgcgcacag cagcgggtcg agatcgagcg cggcgagcgt ttgcgcgtcg aggtcgatcc
    10081 agcacgcgac gaccatgcgc ccgtcgatct gctgcgcggg ccccgcccgg tgcgcgtgca
    10141 cgccgatccg gcggaacagg cgctccatgc tcagaaacgt cacgccgatc agttgcttcg
    10201 cgccaagccg cgcggcgcac tcgacgacgg cggcgagcat cggccgcacc gcccaggccg
    10261 ggttgccgcc cccggccgga tcctcggcgt tcgcggcgaa gcgcgacaat tcccagacgg
    10321 cggcggattg cggcaacggc atgtcttgcg cgaccagcgt cgggaacagt tccttcagca
    10381 gatacgggcg ggtcgtcggc agcagccggg cgcagccgca gatttccccg tcgtcgtcgc
    10441 gggcgaacac atagacggta tcgtcgcgat cgtactgatc ccgctcgaac ccttcgcttg
    10501 ccgacggcag tttccagccg agctgctcga cgaaaactcg gtgccgataa aggcccagat
    10561 cagccgccaa gtcgctcggc aggcgcccgt cgccatgaac gaaagttcgc atgtcgtcct
    10621 cgtgcgtgtg ctttggaatg ggcgcattac atcgcgcgct ccgaggacag gtaactgtta
    10681 acccttacag ggtcgggaaa gcggggctgg tggcgggggc ggggcgggtt ccgccggttt
    10741 tcgtcggtgt cggactgcaa agattcgata atttgcttgt caatccgcaa cgttcgagga
    10801 aaattagaca atatgcactg attgcgccga cgcgcgtcac tgcagggtgg gacccgcatg
    10861 cgcaaaatcg ccgcgacgaa gcatcgcggc ggtgacggcg gacggccagt tcagttgggc
    10921 gagccggcgc gacagtgcgg ccgaggtcgg atccatgccg atgtcgagcc cgttgccgtc
    10981 gacgcccatc acgttgctgc gcacgtcgcc ccatgcaatg acgaaggcgc ccgttgcgcc
    11041 gtcgatgtac cagtcccagc ccactgtgag atgcgccgcg ccggcgctcg acggccgctc
    11101 ccactcggtg tagccggcga tgcgggcgtc gatgtcgctc gcacgtagtt cgacgagcag
    11161 tccggaatcg attccggacg atacgtgaac gagccgcagc tcggcgaacg cgtgcatcgg
    11221 aaggcgcacg tagccgtcgg tggaagagcc gcgaaagcgg tggagccatg gtgaattcat
    11281 gccgcggaat gtatcagccc gcgcgcgtgc tgaaacctag caagtatgac agcgtgaagc
    11341 tgctggagaa cgaatggaac tgcgctggca agacgcctat cttcaattta gcgccgcgga
    11401 gaacgagcag cagctcttcc aacagatcgc cgcgtatacg aagcggctcg gcttcgaata
    11461 ttgctgctat ggcatacgcg tgccgttgcc gatctcgaag ccggtcgtcg cgattttcga
    11521 cacctatccg aacggctgga tggagcgcta ccaggaaatg aactacctgg aggtcgatcc
    11581 gaccgtacgc gagggcgcgc tcagctcgaa catgatcgtc tggccggagg cgagcgcgag
    11641 cgacgcgacg acgctctgga gcgacgcgcg cgatcacggg ctggcggtcg gcgtcgcgca
    11701 gtcgagctgg gcctcgcgcg gggtgttcgg tctcctgacg atcgcgcggc acacggaccg
    11761 cctgacgtcc gccgagatca accatctgac gttgcaggcg aactggctcg cgaacatgtc
    11821 gcactccctg atgagccgtt ttctcgtgcc gaagctcgcg cccgaatcgg gcgtggcgct
    11881 cacgcaccgc gagcgggagg tgctgtgctg gacgggggag ggcaagaccg cgtgcgagat
    11941 cgggcagatc ctcagcatct ccgagcgcac ggtgaacttt cacgtcaaca acatcctcga
    12001 caagctcggc gcgacgaaca aggtgcaggc cgtcgtgaag gcgatcgcga tggggctcat
    12061 cgatgcgccg taagcattgc cgcgagcgcc gtcgcggccg cgcggcgctc actccatcaa
    12121 cggttccgct tccttcgcgg tccagctcac gctggagatg cttttctcca tgctcatccg
    12181 gctcgcgatc tgctcgagct tctgctgatc cttcgggtgc agcttcagcg tcgccgtcac
    12241 cttgatgcgc tcgggcgcat cggcttcgcg cggcacgtcc tcgctcgtca ggctctggaa
    12301 cgacagcggc ttcgcgtaca tcgagttcga cagcagcgtg cggatgtgca cttcgtccga
    12361 tgcgaggcag atcaccgtga tttgatattc gcgcacgaga tcggcgttcg acacgggcgt
    12421 cgcgttgatc gcctggctca cgccgcgcag cagcgtgttg gtgagcagca cgacgcccgt
    12481 gcccgcgagc gcgggcaggt agtggccggc gcccgagagc acgccgaccg cggccgagca
    12541 ccagagggtg gccgcggtgt tgatgccctg gatcgagcct ttgtcgcgca tgatgacgcc
    12601 gccgccgaga aagccgacgc cggagacgac atacgcggcg atctgcgtga cgccggggat
    12661 tccgttgccc gtgagcacgc cgagcgtgac gaacagacac gcgccgctcg cgacgagcgt
    12721 gatcgtgcgc aagccggccg tgcgctggcg gatctgccgt tcgaggccga tggcgacccc
    12781 gcaggcgaac gcggtgaaga ggcgaagtgc gaattcgaaa gtcatgggtg ttctgccgtg
    12841 ccgaatgcgc cgcgcgatgg gcgcggcggc gcacgcttgc cgggcgcgcg tgcattacgt
    12901 acgcgcgcgc cactttagcg cgcgaatcga tgcgattgtg tgaaacggga aatcgcacgc
    12961 gttcttcgat gaacgcgcgc ggcggcgaag cggccggcag gcgttcaggc gaagcggcgt
    13021 gcggacgttg tgctgctact gtccacgacg gttcctgaaa gaatggatgg cgggcattct
    13081 aggcgggacc cgccgtgtga gtcaacccgc gcggcggcgg tgaatgcgcg ggcgcggggc
    13141 gggatgcgtt tcgcgcaggg cacggcggct gcgcgaacgc gcggcggcgg tggcgtggga
    13201 gcggggcgtg cgccgtcgaa atgtcagcgc ggctcgacgg cgcatgtgaa ggcgggcgct
    13261 gctgttgctg tcgcgcatgc gttcccgatg gcgttcggcg ctcggtgttc ggtgttcagc
    13321 gttcagcgtt cagcgttcag cgttcagcgt tcagcgttca gcgttcagcg ttcagcgttc
    13381 agcgttcagc gtgacggacg ccggcgcgcg cgttcggttc ccttcgccgc gcacgagccg
    13441 cacgcgcgtg atttccgacg gcgcgccgag ccgtttcggc ggcccccagt aaccggtgcc
    13501 gcggctcgta tagacccaca ggccgttgag gcgcgcgagc ccggcggtga acggctgctg
    13561 caatcgcacg aagaaattcc acgggaaaaa ctggccgccg tgcgtgtgcc cggacagttg
    13621 cagcgtgaag cccgcatcgg ccgcggcggt tgcgctgcgc ggctggtgcg cgagcagcac
    13681 gcggatgcgc acgtcggcgg gcgcgccggc gagcgccgcg ctcgggtcgc tccgatgcgc
    13741 gggatcgaag tggcccgccg agtaatcggt gacgcccgcg atcacgagcc ggccgtcgcc
    13801 gtggtcgagc gtccgatgct cgttgagcag cacgtcgagg ccgaggcggc ggaactcggc
    13861 gatccactcg tcggcgcccg aatagtattc gtggttgccc gtcacgacga atgcgccgtg
    13921 gcgcgcgcgc agccgcccga gcggcgccgc atggccggcc agttgcgcga ccgtgccgtc
    13981 gacgacgtca cccgtcaccg cgacgagatc cggcgcgagc cggttgaccg cgtcgacgat
    14041 cgcctcgacg tagccgcgct tgatcgtcgg gccgacatgg atgtcgctga tctgcacgat
    14101 cgtgaagccg tcgagcgcgg cgggcagatc gtcgatcggc accgcgacgt cgacgacgcg
    14161 tgcgcggcgt cgcgcattga cgaagccgac gacgctcacc gcgagcgccg cgagcggcac
    14221 gccggccgcc gtctgtatcc gccactgcgc gagcgacacc gcgccgggcg cgagcgcgtc
    14281 gacggtgacg agcgaggcga gcagcacgtc gcgcgcgagc gtgagcacga gcagcgacga
    14341 gaagaagccc atcgcgagga ggccggccca ggcgacgcga tcgccgagcg gctgccgctc
    14401 gaacacgcgc gacagcatgc cgagcggaat cagcaggcac gacccgacga gccacagcgc
    14461 gcccgcgtag cgcgcggcgg gcgaggcgag ctcgggcagc agacggaagc cgacgtacac
    14521 gtgcagcagc acgccgatga tcgtcaggcg cagcagaaac gatgaaacgc gtcgcatggg
    14581 cggaaacggg ggaagtcggg agaggtggcg cggcgcgcga acgcgccgcc gtcgcgcgct
    14641 tattcgatgc gcgcgatttc gtcgaacgag aagcgggggc tgcgcgggaa caggccggcg
    14701 gcgtcgccgt agccgaggtt cacgaggaag ttcgacttga tcgacgtgcc ggcgaagaac
    14761 gccgcgtcga cggcagcctg atcgaagccc gacatcggcc cggcatcgag gccgagcgcg
    14821 cgcgcggcga cgatcagata cgcgccttgc agcgacgcat tgcgaaacgc ggtcgcctcg
    14881 atcagcgcgt cgttgccggc gaaccagctg cgcgcgtccg cgtgcgggaa gagcttcggc
    14941 aggtgatcgt ggaacgccat gtccatgccg acgatcacgg tgacgggcgc ggccatcgtc
    15001 ttcgcgagat tgccttcgga cagcgcgggc ttgagtttgg ccttcgcctc gggcgacttc
    15061 acgaacacga agcgcgcggg gctcgagttc gccgacgtcg ggccccactt gacgagatcg
    15121 atcagttcgc ggagcagcgc gtcgtcgacg ggcttcggct gccatgcgtt atgggtgcgc
    15181 gcggtgcgaa aaatttgatc gagagcggaa tcggaaagag tcatgtcggg aatccgggtg
    15241 agcgcgcaaa cgccgtggcg ttcgcgcggc tagaatttga acaggacggc gcggatcgcc
    15301 ggttgcggtt cgcgccattc cgcgatgata gccggatgcg gagattttga ccgacgatgg
    15361 acgatttgtt cgacgatctg ccgagacccg atgtcgactg gcatccggac tggctcgcgc
    15421 ccgccgacgc cgaccgcttc catgcgcgcc tcgtcgacga ggtcgcgtgg cgccaggaca
    15481 cgatgcgcac gccgcgcggc ctgttgccgc tgccgcgcct gaccgcgtgg cagggcgagc
    15541 cggacgcgct ctacgtgtat tcgggcatcc gcaacgagcc ggcgccctgg acgcccgccg
    15601 tgctcgagct gaagcgaagg gtcgaggcgg caagccgcgc gcgcttcaac agcgtgctgc
    15661 tgaaccgcta tcgcaacggc ttcgacagca tgggctggca tgcggacgac gagccggagc
    15721 tcggcgccga gccggtgatc gcgtcgctga gcctcggcgc gacgcgggtg ttcgatctgc
    15781 ggcacaacga gacgggcgtg acgcacgcgt atcgtttgac gaacggcagc ctgctcgtga
    15841 tgcgcgggcg tacccagcac gcatggcggc accgcgtgcc gaaggagccc gcggtacggg
    15901 gcgagcggat caacctgacg tttcgctggg tgagcgcgcc gcccgccgtc gagcgccgcg
    15961 cgaggccgcg ttcgcgcgga tgacgcgggc ccgcccgcgc gccgaaaccg cgcggccttc
    16021 ggatgatgtc gcgttatgat tcggtttctc tccgtccctt gcagccgaca tggccaaaac
    16081 cactacgacc gccgcgggta gacctgccgc cgacgccgca tcggccaagt cgcgccgtgc
    16141 cgcggccggc gcgcgccccg aacttgacgc ggccgacgac gaagccgcgg gcggcgcatc
    16201 gtcgtacctc gttcccgggc tcgagcgcgg gctgcgaatc ctgtccgaat tttccgcgcg
    16261 cgagccggtg ctgagcgcgc cggagctgtc caagcgcatc ggcattccgc gcacgacgac
    16321 gttccgcctg ctgcagacgc tcgaggcgct cggcttcatc gagcgcgcga acggcgaccg
    16381 ccatttccgg ctcggcatcg gcgtgctgcg gctcggtttc gaatatctga attcgctcga
    16441 attgaccgat ctcggcgcgc cggtgctcga gcgcctgcgc gacgcggccg ggctgtcgac
    16501 gcatctgctg atccgcgacc gccgcgacgt cgtgttcgtc gccaaggcgc agagcaacgc
    16561 accgatgttc ggctcggtga aggtgcacgt gggcacgcgg ctgcccgcgc acgcgaccgt
    16621 gcacggccac gtgttgatgg gcgacctcac gcgcgacgcg atgcgccagc tttatcccga
    16681 gaagcgcctc gaggcgttca ccgaacacac gcccgcgacc gtcgacgaac tgtacgagcg
    16741 cgtgcgccat tacgcgcgtc tcggttacgc gctcagcgaa ggggcgttcg agagcgggat
    16801 ttcggcggtg acggcgccgg tgcgcgacca ttcgggctcg atcgtcgcgg cgatcaccgc
    16861 gacggtgccg cgctcggaaa ttggcgccgt cgacgaaaag gagcggctcg tcgaactcgt
    16921 gtgcggcgcg gccgtcgatt tgtcgcagcg gctgaactac cggccgctcg acagcgatcc
    16981 gaccgtcgcg catgcgcggc acaaggttgc gttgctctga cgacgtccgg ccgcatcgat
    17041 cggggcgagc ggggcgcaca tgcggcgtat tgcggcgcgc gccgcggcgg ccgatgatgc
    17101 cggcgccggg ggcggcatgg cgtaggcagc ggcgcgcgtc ggcggcccgg cgggccgatc
    17161 cccctttcat tgcatttgcc gccgcggaaa ggaaaaagcc tccgttttgc gcggaggctt
    17221 tttcgcattc gtgagcatcg ccgcgatgcg cgccgaagaa acgccacgtc gcttgcgagc
    17281 gccgctcggc acgcgccgtc gccaccgccg cgcgtgtgcg aaacgatgcg ccgcgctcag
    17341 aacgagtggt gaatccccgt caggacaatc acctgattcg ccgtgctcga cgcgcccgcc
    17401 gtgaagaacg cggccttcgc gttgccgctc gcgtgctcgt acagcacgtt cacgtagagc
    17461 tgcgtgcgct tggacagcga atacgtgtcg ccgagctcga actggctcca gcggcggccg
    17521 gcgagcgtcg aagtcgccgc gccgcccgcg atcacgttga acggcgagct ctggtagttc
    17581 gcgccggcgt cgtagctctg gaacgtatcc gagtggccgt tcgcctgcag tttcacgcgc
    17641 gtgtaaaggc cgtgcacgag cagcgggccg aagcggtacg acaggcccgc gcccatgttc
    17701 tgcgccttct tcgcgacata gctcgcgacg ggcatgccct ggaacgtgcc gcccggcccg
    17761 gcgatgccgc cgacggtcgc catcgggaac gcctggtcgt gctcgttcga atagacggcg
    17821 gccgccttga acgggccgtt cgcgtagttc acgccgaagc tcatcgtgcg gccggtcgag
    17881 aagttcgtcg tgttgccgaa gccgagcatc gcgcccaccg tgaagcccgc aaagacgggt
    17941 gaccggtact tgaccgagtt gttgaacggc acggtgctgg tgtccgcgag ctggtcgagg
    18001 ttgccgggat ggaacgcata ccagctctgc gcgaggaatg cgctcgacag cgggtcgagc
    18061 cagtcgaagt tgaacggcgt ctggtggccg agcgtcagcg cgccgagccg gtcggaattc
    18121 aggccgacga acgcctgacg gttccacatc gtgcccgccg ccgccatctg gccgttgttc
    18181 gtatagaagc cgttttcgag ctggaagatc gccttcagac cgccgcccag atcctcgacg
    18241 cccttcagcc cccatcgatc gggctgcgtg ttgccctgaa tcatcgacca cttcgcgccg
    18301 ccgccgacgt tgttcacgta cgcgacgccg gcatcgaggc tgccgtacag cgtgacgctg
    18361 ctctgcgccc acgcgccggc gacggcgagc gcgccgagta atgttgctgc cgcatgcttg
    18421 accatctgat ctcctgacct ttgctccaaa tgacgcgggc ggtggccgcg cgcgaaacga
    18481 tcggccacgc gcgttcccac ggctgagttt ttggctttct tttgttccat atatggaact
    18541 gtgtgccttt ggtggaatgg agtatagggg cagaaatcag cggaaacaaa ataaattttc
    18601 gaatcgaagc ggcggccgcg attcgtccga ggacatgtcg ccaacgcttt gaaagttcga
    18661 gggaaaaccc gaaatttccg cttcttgccg gttccgcctg cattgccggg catcgagcgg
    18721 aaacgcggtc tcggtatttt ccctaggagc ctcggctttt tattttgatc ttcggatgac
    18781 gctcctataa tcaccatcca taaactgacg ttccgtattt ggaacaatca agcgagtcga
    18841 cttgaaggaa gggtgtgaga tgtctgaaca atgggtttgc gccggacacg ccggcgcgct
    18901 gtccgaggat tcgccgatcg agttcaagcg caccgacggc gtcgagatcg ggatctaccg
    18961 cgtcggcgac gacgtgtacg cgctcgagaa cgtctgcccg cacgcgtatg cgctgctcac
    19021 gcaaggcttc gtcgacgagg gcacggtcga gtgcccgctg cacgaggccg tgttcgacat
    19081 caagacgggc cagtgcctga aggggccggg cggccgcgcg ctgaagacgt acgcggtgcg
    19141 gctcgccggc gaggaaatcc agatcaaggt ggaatgacat gaacgagacg accgtgaact
    19201 tcaatccgtt gctcatgccg tggcgcgcgc cgcagccgaa caacgtcgcg ggcaaggggc
    19261 agatcgagat tcccgggcgg atgccgaatc tcgtgtggca gacgcgcaag gccgagccga
    19321 cgcagtacga gaacgatctc ggcgacgcgc tcgagcgcgt gttcgaaagc ggcgcgaccg
    19381 aactcgcgga ggtcgtcgcg ggcctgaacc gcatcggctt tcgcgcgccc gacggcgccg
    19441 agtggaccgc cgagcgcttc tgcgcggagc tcgccgcgct cgccgaatga cgcagccgcc
    19501 ctcaaacgct tccggagcaa acagatgacg tcttccgacc aaacgaattc cggcgccgat
    19561 ccggtgcgtg cgtatctcga ccgcggcatc cgcaactact ggtatcccgt cgcgccgagc
    19621 tggcaggtgt cgagcgcgcc cgtcggcatc actcggttgt ccgaacagat cgtgttgtgg
    19681 cgcgatcggg agggcaacgt gcacgcgctc gaggatcgct gcccgcatcg cggcgcgcgc
    19741 ctgtcgctcg gctggaatct cggcgatcgc gtcgcgtgct ggtatcacgg cgtcgaagta
    19801 aacggcggcg gtaccgtgac gaaggtgccg gccgtgtcga actgtccgct cgaagggcag
    19861 gcctgcgtga agtcgtaccc ggtcgaggag cgtgcgggcg cgatcttcct gtggttcggc
    19921 gacgacgcgc atcgcgagcc cgcgccgctc gttttgcccg acgaactcgt cgcgccggag
    19981 tacgcgcaat tcgtttgcgt gtcgaactgg acctgcaatt accagtacgc gatcgacaac
    20041 gtgatggacc cgatgcacgg cgcgtatctg cacgcgacat cgcattcgat ggccgaaggc
    20101 gacaagcagg ccgacatgcg cgtgcgcagg accgagacgg gcctgatgtt cgagaaggtc
    20161 aatcagcgcg acgtgaactt cgactgggtc gaactcggcg agacgggctg catctggctg
    20221 cgcctcgcga ttccgtatca gcgcaagttc ggccccggcg gcagcttcgg catcgtcggc
    20281 ttcgcgacgc cgatcgacga cgagcactgc caggtctatt tctggcgcac ccgcaaggtt
    20341 gccggctggc agcgcgacgt gtggcgcttc ctgtatcgga accgcctcga ggggctgcac
    20401 tgggcggtgc tcgagcaaga ccgctacgtg ctcgaaagca tggcgccgaa cgcgcgcgat
    20461 cacgaatacc tgtatcagca cgacatcggc gtcacgcgcg tgcggcggat gctgcgccag
    20521 cgcgcgcagg agcatctcgc cgcgctcgac gcgcatcgcg cggcgcaggc cgacgcggcg
    20581 gagcgcgcat gagcgcgccc gtgcaggcga tc
//
