LOCUS       NZ_CP071750            28069 bp    DNA     circular CON 16-APR-2024
DEFINITION  Burkholderia pseudomallei strain VBM21885 chromosome 2, complete
            sequence.
ACCESSION   NZ_CP071750
VERSION     NZ_CP071750.1
KEYWORDS    RefSeq.
SOURCE      Burkholderia pseudomallei
  ORGANISM  Burkholderia pseudomallei
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
REFERENCE   1  (bases 1 to 3203152)
  AUTHORS   Balaji,V., Yamuna,B. and Monisha,P.
  TITLE     Complete genome of Burkholderia pseudomallei_VBM21885
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3203152)
  AUTHORS   Balaji,V., Yamuna,B. and Monisha,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2021) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore, Tamil Nadu 632004, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method :: CANU v. v.1.7; UNICYCLER HYBRID v. v.0.4.6
            Assembly Name                     :: VBM21885
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 39.4x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017378195.1-RS_2024_04_16
            Annotation Date                   :: 04/16/2024 08:15:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,514
            CDSs (total)                      :: 6,439
            Genes (coding)                    :: 6,286
            CDSs (with protein)               :: 6,286
            Genes (RNA)                       :: 75
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 153
            CDSs (without protein)            :: 153
            Pseudo Genes (ambiguous residues) :: 0 of 153
            Pseudo Genes (frameshifted)       :: 85 of 153
            Pseudo Genes (incomplete)         :: 98 of 153
            Pseudo Genes (internal stop)      :: 17 of 153
            Pseudo Genes (multiple problems)  :: 41 of 153
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 225087
            Orig. end                         :: 253156
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071750.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Christian medical college.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28069
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="3"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..28069
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28069
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:18069](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18069)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            1793..2506
                     /locus_tag="J3B47_RS19265"
                     /old_locus_tag="J3B47_19265"
     CDS             1793..2506
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019255914.1"
                     /locus_tag="J3B47_RS19265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19265"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_076852096.1"
                     /transl_table=11
                     /translation="MSTPSAAAKFDPARAAQYAEQSRIALAGYDACHDLAACMLASAIP
                     AEAHAAQVLVAGAGGTAREIAALAGLAPGWRFTAVDPSRPMLDLANANVAAAGLDARVT
                     THLGYVDDLPADARFDGATLIGVLHHVAGDGAKAALLRSIARRLKPGAPLVVAGNYRRY
                     AEHPRLLSAWAQRWRMHGATPEEVARKLATILRGADPPASEDAVHALLDAAGFREPVRF
                     FASLFWGAWIAVRGA"
     gene            2854..3309
                     /locus_tag="J3B47_RS19270"
                     /old_locus_tag="J3B47_19270"
     CDS             2854..3309
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010110174.1"
                     /locus_tag="J3B47_RS19270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19270"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_004190434.1"
                     /transl_table=11
                     /translation="MSVESVRQFLAEKAPDIDVIALSESSSTMTLSAAWDIKPAQIAKT
                     LAMKVGDAHVLLVSCGDSRLDNQKIKAALGGKAKMLSAEETVAVTGHPVGGVCPFGLPA
                     PLPVYCDVMLKSYEFVVPAAGSTHAALRIDPVRLAELVEAEWVDVCK"
     gene            complement(3374..4612)
                     /locus_tag="J3B47_RS19275"
                     /old_locus_tag="J3B47_19275"
     CDS             complement(3374..4612)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011853665.1"
                     /locus_tag="J3B47_RS19275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19275"
                     /product="alpha-hydroxy acid oxidase"
                     /protein_id="WP_004190743.1"
                     /transl_table=11
                     /translation="MANVGKAWNIDDLRKMARKRVPKYFFDYLDGGANSETTMRANEND
                     FARWRLRQKVLTGAQSRVAGLGATYLGAEHRLPILLGPVGFAGMYWSRGEIAAGRAADD
                     AGIGQCLSTFSICSLEDVAAARSGPLYFQLYMFRDRDLTEDILARCRLANVDAVFLTVD
                     TCYIPIRERDARNGFRADTRLSARGVWSMLKRPGWCAGALSHGVPRIGNVLRYPELGAS
                     LLEQSAAVGRMIETRLSWADVKWLRARWPGRIVIKGILDPDDARRAVDEGVDGILISNH
                     GGRQLDPAPSVMDVLPEIAEAVGKRTEILMDGGVRRGADVIKALALGASAVSIGRAYVY
                     GLGAAGEKGVSRCLELLKGEMLPALNMMGFESIAELRAAGKSALRMAVPVHGATAVVEG
                     AEGGARRLTESVL"
     misc_feature    4566..4580
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.52"
                     /tool="antismash"
     misc_feature    complement(4568..4581)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.99"
                     /tool="antismash"
     gene            4865..5275
                     /locus_tag="J3B47_RS19280"
                     /old_locus_tag="J3B47_19280"
     CDS             4865..5275
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195676.1"
                     /locus_tag="J3B47_RS19280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19280"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_165940727.1"
                     /transl_table=11
                     /translation="MDTKHDGGSPIAERRTEGFRLLESGMPQADVARRLVVSRQSVCRW
                     AKRLAERDGRIAKAPGRPRRLNSVQCATLRAMLDDGALAAGFASPQWTLARVRKLIERE
                     FGVAYSKTGGWELLRTLGVSLQRTERHPHIAR"
     gene            complement(5518..6111)
                     /locus_tag="J3B47_RS19285"
                     /old_locus_tag="J3B47_19285"
     CDS             complement(5518..6111)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009907291.1"
                     /locus_tag="J3B47_RS19285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19285"
                     /product="LysE family translocator"
                     /protein_id="WP_004190802.1"
                     /transl_table=11
                     /translation="MRSLVALLFAAAVVMGSPGPSTVSATAMGASYGVRRSLKYAWGLI
                     AGTVAVLLLVSTGVTAFVMSMPSAARILNIVSALYILYLAYRIATAPPLDKRAENLSSP
                     AFKGGFLLAVANPKAYIAIGAVFAGTTLVATDYGLDAAAKIVLLSVMIVIIHLGWLLAG
                     VSLSRFLHDPVASRIINVSLAAILAIVSLIALFE"
     misc_feature    complement(5551..5553)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6163..6172
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     gene            6207..7061
                     /locus_tag="J3B47_RS19290"
                     /old_locus_tag="J3B47_19290"
     CDS             6207..7061
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525118.1"
                     /locus_tag="J3B47_RS19290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19290"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_004533441.1"
                     /transl_table=11
                     /translation="MNDCARDIAPDRDQIRIGSGAPGIERVEAHFLDHAFTPHRHDTYA
                     IGITLSGLQTFGYLGEIHHCLPGQCHILHPDELHDGRAGTDEGFGYRIIYVDPALVQEA
                     LGGRMLPFVRSPIFQAPAVSEALAAGIWNLDEEIDNVSRIDIAVAVANLLTAAAAKGSA
                     PKAGPLAMVELTRIRDIIASCPHEPISMDALEHASGLDRWTIARQFRRLFGTSPSRFRT
                     QRQLNLVRRLLMEGESLSTASTDAGFSDQSHMSRHFKSTYGITPGAWISAVRTRHAQHP
                     SDH"
     misc_feature    6235..6248
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            7294..7620
                     /locus_tag="J3B47_RS19295"
                     /old_locus_tag="J3B47_19295"
     CDS             7294..7620
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195671.1"
                     /locus_tag="J3B47_RS19295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19295"
                     /product="hypothetical protein"
                     /protein_id="WP_004195671.1"
                     /transl_table=11
                     /translation="MPAAFAADRNGKNPHRPAPRACDMNAKAAALHIRRSRRSGHSFGP
                     AFNGCALNIPCRTSARGPHRFSESRYPFPNRAINQEFSDSIPAEFIGHQKFNYPKPITN
                     STIN"
     misc_feature    7629..7644
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            7803..8834
                     /locus_tag="J3B47_RS19300"
                     /old_locus_tag="J3B47_19300"
     CDS             7803..8834
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011853670.1"
                     /locus_tag="J3B47_RS19300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19300"
                     /product="autoinducer binding domain-containing protein"
                     /protein_id="WP_004533219.1"
                     /transl_table=11
                     /translation="MARNRTVLPLERAQVDVVQERSGVVGDRRISLRVCGEATQGYLLE
                     RYHAAPGEPSFVQRVNLFDDATIASFVEHDPYSAELESLYRAVIDVPKKALKFAGHETI
                     QPEFASECVSESGLLTVMRNTILECGATNCFYHYFRIDEKTGNLKNHELLIGGTPVWPH
                     RYVHRHWYLNDPAMAHARNDTRPLRASTLAPLPHDHWLNQQAQFLGLTSNVFFPAHRRD
                     DDTIGLLHVSSSLPAAQGEEIIWRNRRTLRGLATEMLEWKVTAQRNTLAREMSLSHHEL
                     VALRLVGRGANARHVAEELKLQEHAVYQLFTSINKKMNSSHIRTSANKAKQFGFLAEGY
                     ISE"
     misc_feature    8154..8156
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8259..8261
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8901..9503)
                     /locus_tag="J3B47_RS19305"
                     /old_locus_tag="J3B47_19305"
     CDS             complement(8901..9503)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010120151.1"
                     /locus_tag="J3B47_RS19305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19305"
                     /product="LysE family translocator"
                     /protein_id="WP_004525115.1"
                     /transl_table=11
                     /translation="MLIQDALLKMSFYVSLVLIVPGPTNTLLLSSGLKVGLRGTWHLVI
                     AEALGYVVAISLWGFFLLSVAASRPWLFGAIKLLSAAYILWLAVKMWTKSRALHELSAG
                     PISFGDLFVATLMNPKALLFASTMFPLEAFRSLSYFGWAVIVFLIVLAPIGVGWSSLGG
                     LLTSQRSWAAHTSTFMRCASLVLATFSGSLAYSVLGH"
     gene            complement(9541..9954)
                     /locus_tag="J3B47_RS19310"
                     /old_locus_tag="J3B47_19310"
     CDS             complement(9541..9954)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529064.1"
                     /locus_tag="J3B47_RS19310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19310"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_004529064.1"
                     /transl_table=11
                     /translation="MNERGFGAWNRIERETLTERIERQVVSGDALTMARLYLKKGAFVG
                     THSHPNEQLTYILEGRLLFRYGEHLEHEIEVGPGEILHLPANVPHNALCLEDAVDLDVF
                     TPVRTDWLAPGGNRYFAGASAATSPTPVPSASR"
     gene            complement(10001..11044)
                     /gene="dmpG"
                     /locus_tag="J3B47_RS19315"
                     /old_locus_tag="J3B47_19315"
     CDS             complement(10001..11044)
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899155.1"
                     /locus_tag="J3B47_RS19315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19315"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_004525113.1"
                     /sec_met_domain="HMGL-like (E-value: 2.9e-49, bitscore:
                     165.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILISDATLRDGNHAIRHQLSAAQIHAYARAADEAGIDVVEVGHG
                     NGLGGSSCLLGQTPIGDRLMLETARAALRTSRLGVHFIPGLGKAADISLALEIGVDVVR
                     VATHCTEANVSARFIEQTRAAGRTAFGVLMMSHMAPPDALLAQAKLMERYGAQAVVLMD
                     SAGYSTPSLVRAKVERLVDGLDIDVGFHAHNNLGLAVANSLVALEAGARIVDACVKGFG
                     AGAGNTQLETLVAAMEREGHDTRTTFERVMTLARGTETFLNPKTPHIQPANIASGLYGL
                     FSGYVPHIQKAAQEFGVNEFELYKRLAERKLVAGQEDIIIEEASRLARERDVQRATGGV
                     RVRELSA"
     gene            complement(11041..11934)
                     /locus_tag="J3B47_RS19320"
                     /old_locus_tag="J3B47_19320"
     CDS             complement(11041..11934)
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529065.1"
                     /locus_tag="J3B47_RS19320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19320"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_004552044.1"
                     /transl_table=11
                     /translation="MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSD
                     GLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATSAAAHKVNNRFFSDAGKFVIDLTPA
                     KVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIASRSA
                     GIATRENIDEYMTTTEYALAKFSDAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRV
                     RASVADMVEKVREYVPGYRLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAAL
                     AVASHRHATARLGATQ"
     gene            complement(11931..12773)
                     /locus_tag="J3B47_RS19325"
                     /old_locus_tag="J3B47_19325"
     CDS             complement(11931..12773)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Thioesterase (23-241). E-value: 1e-43.
                     Score: 142.4. Matches aSDomain:
                     nrpspksdomains_J3B47_RS19325_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529066.1"
                     /locus_tag="J3B47_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19325"
                     /product="thioesterase domain-containing protein"
                     /protein_id="WP_004529066.1"
                     /sec_met_domain="Thioesterase (E-value: 2e-43, bitscore:
                     146.5, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.5e-08, bitscore:
                     32.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAREAAAESPWLIVHEARNARVRLFCFHYAGATASIFRTWPGGL
                     PDWIEVVAVQLPGREYRLGEPLIEHAEPIVEALADIVPPLLDLPYAFFGHSMGALIAFD
                     LAHLLRARGFAQPLLFVASGRSAPRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALIADP
                     ALRELWLPRLRADLTISATYRYVGPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAV
                     RYVGFSGGHFFMHGEEAGVLAEVRRELERVLARAAQDEPNGMREPAARMSHLTEESGT"
     aSDomain        complement(12051..12704)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J3B47_RS19325_Thioesterase.1"
                     /evalue="1.00E-43"
                     /label="J3B47_RS19325_Thioesterase.1"
                     /locus_tag="J3B47_RS19325"
                     /protein_end="241"
                     /protein_start="23"
                     /score="142.4"
                     /tool="antismash"
                     /translation="RLFCFHYAGATASIFRTWPGGLPDWIEVVAVQLPGREYRLGEPLI
                     EHAEPIVEALADIVPPLLDLPYAFFGHSMGALIAFDLAHLLRARGFAQPLLFVASGRSA
                     PRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALIADPALRELWLPRLRADLTISATYRYV
                     GPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAVRYVGFSGGHFFMHGEEAGV"
     CDS_motif       complement(12447..12509)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J3B47_RS19325_0001"
                     /evalue="1.00E-07"
                     /label="NRPS-te1"
                     /locus_tag="J3B47_RS19325"
                     /protein_end="109"
                     /protein_start="88"
                     /score="24.4"
                     /tool="antismash"
                     /translation="PYAFFGHSMGALIAFDLAHLL"
     gene            complement(12770..13714)
                     /locus_tag="J3B47_RS19330"
                     /old_locus_tag="J3B47_19330"
     CDS             complement(12770..13714)
                     /EC_number="2.6.1.42"
                     /GO_function="GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (51-286). E-value: 1.5e-38.
                     Score: 124.8. Matches aSDomain:
                     nrpspksdomains_J3B47_RS19330_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529067.1"
                     /locus_tag="J3B47_RS19330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19330"
                     /product="branched-chain amino acid transaminase"
                     /protein_id="WP_004529067.1"
                     /transl_table=11
                     /translation="MKSSYVWKNGELVPWEHAQVHVMSHALHYGTSVFEGVRAYEIGEK
                     AAILCGREHFERLLFSCKVARIASPMSVGQWMEATVETLRANGQRSAYIRPLVYRGAGE
                     SLGLDARQCPAEALLITTPWGAYLGDEALQQGVDVQVSSWRRNGAGAASTLAKIGGQYV
                     NGQAIVMEAHENGMSEGIALDTNGFVSEGSGENVFLVYKNEIFTPSIGSSILSGITRHC
                     VIRIARDLGYTVTETSIPREMLYLADEIFFTGTAVEICPVRSVDRMPVGSGKRGAVTKA
                     IQDQYFGIVRGTHADKWNWLTPVAVPSRDGARA"
     aSDomain        complement(12857..13561)
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J3B47_RS19330_Aminotran_4.1"
                     /evalue="1.50E-38"
                     /label="J3B47_RS19330_Aminotran_4.1"
                     /locus_tag="J3B47_RS19330"
                     /protein_end="286"
                     /protein_start="51"
                     /score="124.8"
                     /tool="antismash"
                     /translation="REHFERLLFSCKVARIASPMSVGQWMEATVETLRANGQRSAYIRP
                     LVYRGAGESLGLDARQCPAEALLITTPWGAYLGDEALQQGVDVQVSSWRRNGAGAASTL
                     AKIGGQYVNGQAIVMEAHENGMSEGIALDTNGFVSEGSGENVFLVYKNEIFTPSIGSSI
                     LSGITRHCVIRIARDLGYTVTETSIPREMLYLADEIFFTGTAVEICPVRSVDRMPVGSG
                     KRGAVTKAIQDQY"
     misc_feature    13682..13697
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(13729..14412)
                     /locus_tag="J3B47_RS19335"
                     /old_locus_tag="J3B47_19335"
     CDS             complement(13729..14412)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006027931.1"
                     /locus_tag="J3B47_RS19335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19335"
                     /product="RraA family protein"
                     /protein_id="WP_004525109.1"
                     /transl_table=11
                     /translation="MAQWNSDDELFALMRAELSTCPVSDVMEVLGFAYPMLPPEIRPLR
                     RDMVMIGRAMPVQDEPPVPHGGLKRYDAKPFGLLFESVEALRPGEVYIASGGPTAVARL
                     GDLLVTRARNLGAAGVVLHAHVRDANAILDLNLPAFAHGTYAYGLQGRHNVVDYRCSIT
                     VGHVRIRPGDLIFGDGDGVCVIPREAEREVITRAIAKNRLERKVRGAIAEGRSVVEAFN
                     QYNVM"
     gene            complement(14420..15217)
                     /locus_tag="J3B47_RS19340"
                     /old_locus_tag="J3B47_19340"
     CDS             complement(14420..15217)
                     /NRPS_PKS="Domain: Thioesterase (27-252). E-value: 5.3e-49.
                     Score: 159.6. Matches aSDomain:
                     nrpspksdomains_J3B47_RS19340_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009978083.1"
                     /locus_tag="J3B47_RS19340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19340"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_004525108.1"
                     /sec_met_domain="Thioesterase (E-value: 9e-46, bitscore:
                     154.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGADMNACEARWFLFGADERKPDARIRLFCFHYAGSGGSIFRHW
                     GEALPDDVELVAVQMPGRENRLNEPLLYSMDEAVPPLVDALAPLLDRPFAFFGHSTGAL
                     IGFEVARVLRARGYPQPRLLIASAQNAPDVKPEVIRHRLSDAEFVEVLRGCNGTPDAIL
                     QDPALLELLLPRIRADGAVFETYRYERQAPLDCRIVVFHGAADALVHDAGLARWAGETQ
                     HSFARYRFAGDHFFIHDEEASVLDHINRELEPLLSDASSTLIG"
     aSDomain        complement(14462..15136)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J3B47_RS19340_Thioesterase.1"
                     /evalue="5.30E-49"
                     /label="J3B47_RS19340_Thioesterase.1"
                     /locus_tag="J3B47_RS19340"
                     /protein_end="252"
                     /protein_start="27"
                     /score="159.6"
                     /tool="antismash"
                     /translation="RLFCFHYAGSGGSIFRHWGEALPDDVELVAVQMPGRENRLNEPLL
                     YSMDEAVPPLVDALAPLLDRPFAFFGHSTGALIGFEVARVLRARGYPQPRLLIASAQNA
                     PDVKPEVIRHRLSDAEFVEVLRGCNGTPDAILQDPALLELLLPRIRADGAVFETYRYER
                     QAPLDCRIVVFHGAADALVHDAGLARWAGETQHSFARYRFAGDHFFIHDEEASVLDHIN
                     REL"
     CDS_motif       complement(14579..14596)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J3B47_RS19340_0004"
                     /evalue="2.30E+01"
                     /label="NRPS-beforete1"
                     /locus_tag="J3B47_RS19340"
                     /protein_end="213"
                     /protein_start="207"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="LVHDAG"
     CDS_motif       complement(14606..14626)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J3B47_RS19340_0003"
                     /evalue="3.80E+01"
                     /label="NRPS-beforete1"
                     /locus_tag="J3B47_RS19340"
                     /protein_end="204"
                     /protein_start="197"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="IVVFHGA"
     CDS_motif       complement(14879..14944)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J3B47_RS19340_0002"
                     /evalue="8.30E-06"
                     /label="NRPS-te1"
                     /locus_tag="J3B47_RS19340"
                     /protein_end="113"
                     /protein_start="91"
                     /score="18.3"
                     /tool="antismash"
                     /translation="RPFAFFGHSTGALIGFEVARVL"
     CDS_motif       complement(15110..15133)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J3B47_RS19340_0001"
                     /evalue="1.30E-02"
                     /label="NRPS-beforete1"
                     /locus_tag="J3B47_RS19340"
                     /protein_end="36"
                     /protein_start="28"
                     /score="8.7"
                     /tool="antismash"
                     /translation="LFCFHYAG"
     gene            complement(15221..16126)
                     /locus_tag="J3B47_RS19345"
                     /old_locus_tag="J3B47_19345"
     CDS             complement(15221..16126)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004533401.1"
                     /locus_tag="J3B47_RS19345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19345"
                     /product="chlorinating enzyme"
                     /protein_id="WP_004525107.1"
                     /sec_met_domain="PhyH (E-value: 1.4e-35, bitscore: 120.8,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKRFHLSEAEKKFFYENGYAGPFTLYEPEEMTRVWEEVRMDLLD
                     TAKAAFPNSKLNYDRHLDMLSLNQIISHPKIVDRISSILGPDVLSWRTEWFPKYPGDEG
                     TDWHQAESFVEFEGTEKLEPTAAEEGRPWELTAWIAMSEATKENGCLKLMPGSHRTWFF
                     DEKRNIPFEPENFNKRVLDDGQKSGFYGYDYEKLKLDPSWKPDEARAVHMEVKPGQFFI
                     FTSRCMHGSNPNTSKDSVRFGWATRFVPTHVKVYAGQDSFHHFGEVLPLDRYSTVLVAG
                     EDRYGHNRVTKPLAAVAALA"
     misc_feature    16111..16122
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.79"
                     /tool="antismash"
     gene            complement(16223..16483)
                     /locus_tag="J3B47_RS19350"
                     /old_locus_tag="J3B47_19350"
     CDS             complement(16223..16483)
                     /NRPS_PKS="Domain: PCP (3-72). E-value: 2.6e-13. Score:
                     42.0. Matches aSDomain: nrpspksdomains_J3B47_RS19350_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525106.1"
                     /locus_tag="J3B47_RS19350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19350"
                     /product="acyl carrier protein"
                     /protein_id="WP_151269965.1"
                     /sec_met_domain="PP-binding (E-value: 8.1e-11, bitscore:
                     39.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTETMLIQILESVIGVKKVTGDTRFLDIGGNSLNLVEVLKQIKA
                     KTGVAPSPRLFFDKTRSTVAALSAEIDTLREMSSAVAPVAG"
     aSDomain        complement(16268..16474)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J3B47_RS19350_PCP.1"
                     /evalue="2.60E-13"
                     /label="J3B47_RS19350_PCP.1"
                     /locus_tag="J3B47_RS19350"
                     /protein_end="72"
                     /protein_start="3"
                     /score="42.0"
                     /tool="antismash"
                     /translation="ETMLIQILESVIGVKKVTGDTRFLDIGGNSLNLVEVLKQIKAKTG
                     VAPSPRLFFDKTRSTVAALSAEID"
     gene            complement(16480..18069)
                     /locus_tag="J3B47_RS19355"
                     /old_locus_tag="J3B47_19355"
     CDS             complement(16480..18069)
                     /NRPS_PKS="Domain: AMP-binding (9-418). E-value: 1.5e-95.
                     Score: 312.1. Matches aSDomain:
                     nrpspksdomains_J3B47_RS19355_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009959911.1"
                     /locus_tag="J3B47_RS19355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19355"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_004553598.1"
                     /sec_met_domain="AMP-binding (E-value: 5.5e-106, bitscore:
                     351.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARHIVQAIQSHAFATPYKCALSDSRGDLGYADLDSFSTRFAMRL
                     QDLGCRPGDRVVMLASRRALLVAAIIGVFKAGCVHVPLDPRMPADRLRYILHDVAPTLV
                     IADEDLIDAIEHALPAAAPIVPVTELERLLDDADSPRLDALVQPLPLPPLDERAIAYCI
                     YTSGSTGRPKGVLINHRSIADFFEGTRAVYDVTAQSRCASFSPLNFDVYLMDMLFPLAQ
                     GASLYVHDDVNAPDLLFDAIRAHDVTHFSAWGMMLGLIAQAEEFESAPLPHLKTILTGT
                     DVPDVKTVQRWLRKSAGVQVINAYGPTEATCAATAHVIREIEPERRTLYPIGKPLEHVR
                     ALLVDEGGNRITAPGVPGELMIGGTQVMQGYWNLPEETAARLVRLDGVPFYRTGDVCAY
                     LADGSLYYMGRKDNEVKIGGYRIHLSEIQRVINSVPHVYGSEVVLLESRYGETLLAAGV
                     LLERGAPLDADCKADEIRQRLAAELPAYMVPRHVKVLEQFPQLSSGKTDRKALLSILQQ
                     RINESNQEEVNS"
     CDS_motif       complement(16786..16851)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J3B47_RS19355_0004"
                     /evalue="2.80E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="J3B47_RS19355"
                     /protein_end="428"
                     /protein_start="406"
                     /score="26.1"
                     /tool="antismash"
                     /translation="YMGRKDNEVKIGGYRIHLSEIQ"
     aSDomain        complement(16816..18042)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J3B47_RS19355_AMP-binding.1"
                     /evalue="1.50E-95"
                     /label="J3B47_RS19355_AMP-binding.1"
                     /locus_tag="J3B47_RS19355"
                     /protein_end="418"
                     /protein_start="9"
                     /score="312.1"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="QSHAFATPYKCALSDSRGDLGYADLDSFSTRFAMRLQDLGCRPGD
                     RVVMLASRRALLVAAIIGVFKAGCVHVPLDPRMPADRLRYILHDVAPTLVIADEDLIDA
                     IEHALPAAAPIVPVTELERLLDDADSPRLDALVQPLPLPPLDERAIAYCIYTSGSTGRP
                     KGVLINHRSIADFFEGTRAVYDVTAQSRCASFSPLNFDVYLMDMLFPLAQGASLYVHDD
                     VNAPDLLFDAIRAHDVTHFSAWGMMLGLIAQAEEFESAPLPHLKTILTGTDVPDVKTVQ
                     RWLRKSAGVQVINAYGPTEATCAATAHVIREIEPERRTLYPIGKPLEHVRALLVDEGGN
                     RITAPGVPGELMIGGTQVMQGYWNLPEETAARLVRLDGVPFYRTGDVCAYLADGSLYYM
                     GRKDNEVKIG"
     CDS_motif       complement(16927..17010)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J3B47_RS19355_0003"
                     /evalue="5.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="J3B47_RS19355"
                     /protein_end="381"
                     /protein_start="353"
                     /score="41.1"
                     /tool="antismash"
                     /translation="PGVPGELMIGGTQVMQGYWNLPEETAAR"
     CDS_motif       complement(17533..17592)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J3B47_RS19355_0002"
                     /evalue="3.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="J3B47_RS19355"
                     /protein_end="179"
                     /protein_start="159"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYCIYTSGSTGRPKGVLINH"
     CDS_motif       complement(17818..17856)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J3B47_RS19355_0001"
                     /evalue="1.10E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="J3B47_RS19355"
                     /protein_end="84"
                     /protein_start="71"
                     /score="12.5"
                     /tool="antismash"
                     /translation="GVFKAGCVHVPLD"
     gene            complement(18117..18401)
                     /locus_tag="J3B47_RS32970"
     CDS             complement(18117..18401)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004529069.1"
                     /locus_tag="J3B47_RS32970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_004544618.1"
                     /transl_table=11
                     /translation="MDAATNDAHSRRRRAVRIEPASCAFASVARRVPRDPAPWAVRRRT
                     GGRYKKATSSLRESSKQSNDEGPVVVGGRTCSANAHAVPSGRLPVRNAA"
     misc_feature    18518..18533
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            complement(18696..18929)
                     /locus_tag="J3B47_RS32975"
     CDS             complement(18696..18929)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009940991.1"
                     /locus_tag="J3B47_RS32975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_076916894.1"
                     /transl_table=11
                     /translation="MTSGRAARDPASRTHRVTICAGMPGRGLVRAFPRKTAEASPRRHA
                     VDRGDTGFRRTLHRRSMKRFGRHREHRVNGGR"
     misc_feature    19221..19235
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.74"
                     /tool="antismash"
     gene            complement(19300..19665)
                     /locus_tag="J3B47_RS19360"
                     /old_locus_tag="J3B47_19360"
     CDS             complement(19300..19665)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004544760.1"
                     /locus_tag="J3B47_RS19360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19360"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_004525103.1"
                     /transl_table=11
                     /translation="MSTRAEGRTSRAPLKRAQLRDCAEVFAALGDETRLRIVAALCAGT
                     ALSIAQITAGTDITRQSVTQHLLVLAQAGLVHDVKVGRERRWSFDPARIDAARAALDAI
                     GRQWDQALLRLRQAVEG"
     gene            complement(19649..20110)
                     /locus_tag="J3B47_RS19365"
                     /old_locus_tag="J3B47_19365"
     CDS             complement(19649..20110)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (6-147). E-value:
                     5.8e-10. Score: 31.7. Matches aSDomain:
                     nrpspksdomains_J3B47_RS19365_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010120211.1"
                     /locus_tag="J3B47_RS19365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19365"
                     /product="SRPBCC family protein"
                     /protein_id="WP_004525102.1"
                     /transl_table=11
                     /translation="MNTSTDRIEKRIVLNAPRSRVWRALTNADEFGAWFRVDLAGQTFE
                     AGRCVEGRITYPGYEHLVLRMRIERIEPEHRFSYHWHPAAIDPAVDYAQETPTLVVFEL
                     ADVAGGTLLTVVESGFDKLPIERRAEAFRMNDGGWGEQMTNIAAHVDAR"
     aSDomain        complement(19670..20092)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J3B47_RS19365_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.80E-10"
                     /label="J3B47_RS19365_Polyketide_cyc2.1"
                     /locus_tag="J3B47_RS19365"
                     /protein_end="147"
                     /protein_start="6"
                     /score="31.7"
                     /tool="antismash"
                     /translation="RIEKRIVLNAPRSRVWRALTNADEFGAWFRVDLAGQTFEAGRCVE
                     GRITYPGYEHLVLRMRIERIEPEHRFSYHWHPAAIDPAVDYAQETPTLVVFELADVAGG
                     TLLTVVESGFDKLPIERRAEAFRMNDGGWGEQMTNIA"
     gene            complement(20257..20910)
                     /locus_tag="J3B47_RS19370"
                     /old_locus_tag="J3B47_19370"
     CDS             complement(20257..20910)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015603248.1"
                     /locus_tag="J3B47_RS19370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19370"
                     /product="DUF1345 domain-containing protein"
                     /protein_id="WP_004529073.1"
                     /transl_table=11
                     /translation="MTFYPQVLRNRPRMVIAVAAGVALGLLFPYPLRPFARVLIGWDCT
                     IWLYLVLMWVRMVRAHHHKVREIAMREDENATMVLTIICFATVASIAAIVLELVSAKSV
                     GFRSGLGHYAVTGATMFGAWFLIPTIFTLHYARLYYLSPKEARAMAFPDRELEPDYWDF
                     LYFSFTIAVASQTADVSLRGRSIRRAALAQSILSFYFNMAVLGLSVNVAAGLLS"
     misc_feature    complement(20839..20841)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21032..21766
                     /locus_tag="J3B47_RS19375"
                     /old_locus_tag="J3B47_19375"
     CDS             21032..21766
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004525100.1"
                     /locus_tag="J3B47_RS19375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19375"
                     /product="metallophosphoesterase"
                     /protein_id="WP_004529074.1"
                     /transl_table=11
                     /translation="MDTAPLIRRHTANHAGRDFVVGDLHGCVDPLRALLHTVRFDPARD
                     RLFSVGDLVDRGAQSEAALALLERPWFHCVLGNHEDVLCSVADGKLPMSVWQRIGGEWA
                     ADLPAATLARHARRLRELPLVRVVGEGDARFNVLHAEFFGSDADLDRGDYAPDVITRLL
                     WGRELAYGRTDPAARQAGLSTTYCGHTPMHDVVRIGAQTFVDTGAFDPSGRLTLLDAKS
                     GESWSMSVAAARHQGAADVPLP"
     gene            complement(21860..22567)
                     /locus_tag="J3B47_RS19380"
                     /old_locus_tag="J3B47_19380"
     CDS             complement(21860..22567)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019255919.1"
                     /locus_tag="J3B47_RS19380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19380"
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="WP_004552047.1"
                     /transl_table=11
                     /translation="MGVTSPERQTNWPTASLDWAPAYRVIPTRFPAINLFDRVASAEDF
                     DALYALEALTNDRVRTEVGMLDLVPPQERRFGPGYGPIMAAFTHLNPNGSRFSDGSYGV
                     FYCARARNTAIAETRYHTSLFLAATKEPPMRQQMRLYTVAAQGEVADVRAWRERDPALL
                     DLVDYSAGQALGRAVRDAGGAGIAYPSVRDPGGECLAAFRTTLLHDCRHAAYLEYNWNG
                     AAIDAVFELNQVG"
     gene            complement(22558..22977)
                     /locus_tag="J3B47_RS19385"
                     /old_locus_tag="J3B47_19385"
     CDS             complement(22558..22977)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895626.1"
                     /locus_tag="J3B47_RS19385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19385"
                     /product="MbcA/ParS/Xre antitoxin family protein"
                     /protein_id="WP_004525097.1"
                     /transl_table=11
                     /translation="MSRPALKPFSTPPAATVEQMSAAGLRAFFNIARDWNLSTDEQLVL
                     LGSPGRSTFFKWKASPQTARLTHDTLERLSLVLGIYKALQILLPQPAAADSWVKRPNDA
                     APFNGKRALDRMLAGNVSDLVAVRQYLDAARGGWA"
     misc_feature    22949..22960
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.06"
                     /tool="antismash"
     misc_feature    23028..23041
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.41"
                     /tool="antismash"
     misc_feature    23030..23043
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.96"
                     /tool="antismash"
     gene            complement(23709..24617)
                     /locus_tag="J3B47_RS19390"
                     /old_locus_tag="J3B47_19390"
     CDS             complement(23709..24617)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020415508.1"
                     /locus_tag="J3B47_RS19390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19390"
                     /product="metal-dependent hydrolase"
                     /protein_id="WP_004525095.1"
                     /transl_table=11
                     /translation="MNQPAKSTDPVSVMPVRRDLRFNLPVERATDWHGQGSQVSHFFNA
                     LSLLFPAGERFFMDSVRNYRDRIDDPVLKKQVLGFIGQEAMHTREHVEYNELMHANRLP
                     ARTVDRRVWKVTGWMKKVLPHSVQLAHTVAAEHYTAMLANWLLSEPAALAGSHEGYKQM
                     WLWHALEETEHKAVSFDVWNTVMKPGPKRYLIRIGVYLLTTMTFWPNVFLIHSQLIRWD
                     RKSDKSVRGLWRVVSLLYGPRHGMFPAIAREWLSFFRPDFHPWDYDNHHHLARVDAIVE
                     ATQAREARKLAAVELDGAKPA"
     gene            24635..24847
                     /locus_tag="J3B47_RS19395"
                     /old_locus_tag="J3B47_19395"
     CDS             24635..24847
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004548817.1"
                     /locus_tag="J3B47_RS19395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19395"
                     /product="hypothetical protein"
                     /protein_id="WP_050868550.1"
                     /transl_table=11
                     /translation="MVAGNVREGPRERHAARKPVAAHAGRAFARSDVSAPSRLHGHRAQ
                     KAPPGLAPAARARARSLAADLYINN"
     gene            25127..25468
                     /locus_tag="J3B47_RS19400"
                     /old_locus_tag="J3B47_19400"
     CDS             25127..25468
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004537279.1"
                     /locus_tag="J3B47_RS19400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19400"
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="WP_004525093.1"
                     /transl_table=11
                     /translation="MTVVTTESGLKYEDLTEGSGAEARAGQTVSVHYTGWLTDGQKFDS
                     SKDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGVIPPNATL
                     VFEVELLDV"
     gene            25531..26298
                     /locus_tag="J3B47_RS19405"
                     /old_locus_tag="J3B47_19405"
     CDS             25531..26298
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895622.1"
                     /locus_tag="J3B47_RS19405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19405"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_004544598.1"
                     /transl_table=11
                     /translation="MTRLAAPSLSLRRYGAVQASDVHDFHQIVLGVDGAMTMTVDGVDE
                     RIDRRCAWLIPAGARHDYAGLADNSQLVLDLPPGSLAVPERLFERARTMAIDPGLTTLV
                     GELASRIARGPLADAASARRLHWQAAARLCGALVGELGGAPSQPAVGLDFARIDGWLRA
                     HLAQPLRIADLAAHCGFGMRRFHQLFCEAFGETPHRYLQRLRLDAAVMLLGDPKHSLTD
                     IASEVGFADQSAFTHAFTKRFGLAPGRWRSDRH"
     gene            complement(26587..27753)
                     /locus_tag="J3B47_RS19410"
                     /old_locus_tag="J3B47_19410"
     CDS             complement(26587..27753)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004544567.1"
                     /locus_tag="J3B47_RS19410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J3B47_19410"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_004525091.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 4.1e-34,
                     bitscore: 115.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHTETSIKSLQIGMHWFPERAGGLDRMYYSLVGALPSAGVAVRG
                     VVAGSERVAADTGGAIRGFGPATSSLPRRMIAARHALRDVMRIERPDVVSSHFALYTFP
                     GLDVTRGIPQVSHFQGPWADESHVEGADSLGQKVKHRLEQAVYARSSRLIVLSHAFGQI
                     LTSRYNVDPARVRVVPGCVDTAQFDLPMTPADARRKLQLPQDRPIVLAVRRLVRRMGLE
                     DLIDAVKTVRRRHPDVLLLIAGKGRLEGELRKRIDDAELGENVKLLGFVPDNHLAALYR
                     AATLSVVPTVALEGFGLITVESLASGTPVLVTPVGGLPEAVAGLSEALVLPEVGAAAIA
                     DGLAAALSGSLVLPDADACRRYARAHFDNTVIARRVAAVYEEAIRAAV"
ORIGIN
        1 acgcgatccc gcgcgcgcgc cggcgtttcg aacacgatcg ttccgtccgg cgcgccatga
       61 aacggcaacg cctgcggcga caggttcagc gcgatgctga gcgtctcgcc gtcgccgagc
      121 cgccatgcgg cgacaagcgc atcggcctcg acgccgtcgg ccgcgcgcag catgtcggcg
      181 cggcgcggcc gcacgtcgat caggcgcggc gcgatcagct tcgcgcgcac cgcgagcgcc
      241 gattgcacga aatggcgccg cgacgcgtcg cccgcggctt catcgaagat cagcggaatc
      301 tgcggcgtca gcagcgacag cgcgagcgcc gcgagatccg cctcgcgcgc gtcgcgcacg
      361 acgccgtcgg acagcacgag cgaggtcagc ggcaggccga cgtcggccat cccgccttcg
      421 ccggccggat gcgcgcgctg gaacaccgcg ccgttcgcgg tcaacgcgcg cgcaagcgca
      481 tggatcgact gatgcgtcga cacgccgtcg ccgtgcgcgc gatcgcggcg ccccgtcagc
      541 cggtacagcg cgcgctcgcc gcaaccgttc cattgcgcgt cgaaatgcgt gtcggcgagg
      601 tgcgacggat gccgctcgct gccgagcacg aggtgcacga tccggtcggt cggcatcgcc
      661 gcgtgcacgc gatcggcgat ctcgcgcagc cacgcgctgt cgatgcggtc cgcctcgcgg
      721 atccgcaagc cgtcgcatcg atattcttcg agccagtaca gcgcgttgtc gcagaagaag
      781 tcgcacacct gcgggtggtc gagcgcgagc ggcggcgcct gcagcggatc gtcgcgggtg
      841 tggaagaacg gctgcgcgta gcgccgcatt tcatcggagc cgcagccgaa gcgcgcatag
      901 tcgagatcga gcagcaccgc gaggccgaaa ccgtgcgcct cgtcgatcag gcgcttgagc
      961 gcgtcgacgc cgccgtatgc ggcgatcggc gcgaacggca ggctgtcgtc gcgcgcctgc
     1021 ggcgccgcga gcaactcgag cgcggtgacg cccaactgcg cgagctgcgg caagcgctca
     1081 cggacaccgt cgtaaccgcc cgccgcgccg ggctggatcg cgtagagcgc gatctcctcc
     1141 cacggcctgc cacgccagaa cgtgtggcgc cacgtgaacg cgcgcggatc gatcacctcg
     1201 ctcggcccgt cggcgccttc cggctgcgag cgcgacgccg gatcggggat cgtcagcgcc
     1261 tcgtcgagcc gataccggta gcgcgtatgc gcgccgcaat cggcgaacgt ctcgaaccag
     1321 ccgtcgcccg cgggcgccat cggcaattca tgcaggccgc ccgcggtgtc gagcgcgagc
     1381 gtcacggccg catgcgcggg cgcccagacg cgaaagtgag tgcgtgtcgt cgcgcccgcg
     1441 gcgccgcagg gctgggcgcc gaacggcagg caatgcgagt gatgctgcgc atacggatca
     1501 tgaggacatt cggacatgat gcgctcctcc tgcgctcaga ggcatggcga agcgccgtgt
     1561 gcggcgcgca tgcgtgacgc gcgtggcccg acgaagaagg ggcacccagt atgcgccgat
     1621 tcgcattacg atgcgagatt cggcgggagg ttttaaacgt gaagcgaccc cgaaatggcc
     1681 ggtagccgcc ataccatgat ggccgctcgc cttgttgcgc gccgcgtcgg cgcttaggct
     1741 gcggtttcgc gcgccattgt cggcgacgcg attcgtcagg agtccgatcg ccatgtccac
     1801 gccgtccgcc gcagccaaat tcgatccggc gcgcgcagct caatacgccg agcaaagccg
     1861 catcgcgctc gcgggctacg acgcatgcca cgacctcgcc gcttgcatgc tcgcttcggc
     1921 gatccccgcc gaagcgcatg ccgcgcaggt ccttgttgcg ggcgcgggcg gcaccgcgcg
     1981 cgaaatcgcc gcgctcgccg gcctcgcgcc cggctggcgc ttcacggcgg tcgacccgtc
     2041 gcggccgatg ctcgatctcg cgaacgcgaa cgtcgccgcg gccggtctcg atgcgcgcgt
     2101 gacgacgcac ctcggctatg tcgacgattt gcccgccgac gcccgcttcg acggcgcgac
     2161 gctgatcggc gtgctgcacc acgtggccgg cgacggcgcg aaggccgcgc tgctgcgctc
     2221 gatcgcacgc cggttgaagc cgggcgcgcc gctcgtcgtc gcgggcaact atcgccgcta
     2281 cgccgagcat ccgcggctcc tgagcgcgtg ggcgcagcgc tggcggatgc acggcgcgac
     2341 gccggaagaa gtcgcgcgca agctcgcgac gatcctgcgc ggcgcggacc ctcccgcatc
     2401 cgaggatgcg gtgcatgcgc tgctcgacgc cgccgggttc cgcgagccgg tgcgattttt
     2461 cgcgagtctg ttctgggggg catggatcgc ggtgcgcggc gcatgaacgg gcttgccggc
     2521 aacccggccc gcggcgcccg ggacccccgc cccccgcaac ggcggccgcg acatcgcgcg
     2581 ccggcgcgag cgccgcgcgt acgcgcgccc cgcgcggcgc aaaccatgcg cggcgcgccg
     2641 aaccgcgatc gggccgcgct cacctcgaac gtcatgcatc gatgactgcc ccgggcgagc
     2701 ttgcacaatc gttcaataca acttgcgccg agtgcgttag cttatccgtt ccgagggttc
     2761 accaaagatg cgggagcaag gatcgtcgag cctgcccttg ctcccgccga taatacaaaa
     2821 gcgggcatgc aggctgcacg gagggccacg aacgtgagtg ttgaatcggt tcgccagttc
     2881 ctggcggaaa aggcgccgga tatcgatgtc atcgcgctga gcgaaagcag ttccacgatg
     2941 acgctgtcgg cggcctggga catcaagccg gcgcaaatcg ccaagacgct cgcgatgaaa
     3001 gtcggcgacg cacacgtatt gctcgtatcc tgcggcgatt cccgcctcga caaccagaaa
     3061 atcaaggccg cgctgggcgg caaggcgaaa atgctctccg cggaggaaac ggtcgccgtc
     3121 accggccatc cggtgggcgg cgtttgcccg ttcggccttc cggctccgtt gcccgtttat
     3181 tgcgacgtga tgttgaagtc gtacgagttc gtcgtgccgg ccgcgggctc gacgcatgcc
     3241 gcgttgcgca tcgatccggt ccgcctggcc gagctggtcg aagccgaatg ggtcgacgtc
     3301 tgcaagtagc ctgcgtgatg agcgccgtgc gccgccggtt gcggcgccac ggcacgccat
     3361 cggcacgttg acgctacagc acgctctccg tcagtctacg cgccccgccc tccgcccctt
     3421 cgacaaccgc cgtcgcgcca tgaaccggca ccgccattcg caacgcggac ttgcccgcgg
     3481 ccctgagttc cgcgatcgat tcaaagccca tcatgttgag cgccggcagc atctcgccct
     3541 tcagcaattc gagacatcgc gagacgccct tctcacccgc cgcaccgagc ccatagacgt
     3601 aggcgcgccc gatcgagacc gcgctggccc cgagcgccag cgccttgatc acgtccgcac
     3661 cgcgccgcac accgccgtcc atcaggatct cggtgcgctt gccgaccgcc tcggcgatct
     3721 ccggcaacac gtccatcacc gacggcgccg gatcgagttg ccggccgcca tgattcgaga
     3781 tcaggatgcc gtcgacgccc tcgtcgaccg cgcgccgcgc gtcgtcggga tcgagaatcc
     3841 ccttgatgac gatcctgccg ggccagcgcg cgcgcagcca cttgacgtcg gcccaggaca
     3901 agcgcgtctc gatcatccgg ccgaccgccg cggattgctc gagcaacgat gcgccaagct
     3961 ccggatagcg cagcacgttg ccgatcctcg gcacgccatg ggacaatgca ccggcgcacc
     4021 agcccgggcg cttgagcatc gaccataccc cgcgcgccga caagcgcgta tcggcgcgaa
     4081 acccgttgcg cgcatcgcgt tcgcgaatcg ggatatagca ggtgtccacc gtcagaaaga
     4141 cggcgtcgac gttcgccagc cggcagcgcg cgagaatgtc ctcggtcaga tcgcgatcgc
     4201 ggaacatgta gagctgaaaa tacagcggac cggagcgcgc cgcggcgaca tcctcgagcg
     4261 aacagatcga gaacgtcgac aaacactgac cgatgcccgc gtcgtcggcc gcgcgtcccg
     4321 ccgcgatctc gccgcgcgac caatacatgc cggcaaatcc caccggcccg agcagaatcg
     4381 gaagccgatg ctcggcgccg aggtatgtcg cccccaaacc cgcaacccgg ctctgcgcgc
     4441 cggtcaatac tttctgacgc agccgccagc gcgcgaaatc gttttcgttc gcgcgcatcg
     4501 tggtttcgct gttcgcgccg ccgtccagat aatcgaagaa atatttgggc acgcgctttc
     4561 gcgccatttt tctcaaatca tcgatgttcc aagccttgcc gacattggcc atctgaattc
     4621 ttctccgttc tccgccggcg caccgcgggc gttcgtcttc gggcgtgcgc cggatgcgca
     4681 cgctcattgc gctcacaccg gcgcaccgcg atcaggtctt cgtcgcaatc attccgatcc
     4741 agcaggattt ccacctcgac tgcgtcatgg acattctaat gtgatcttca tcggccttgc
     4801 gtcgctcttt tcaatcattt agcaatccgt cacgtccatg agtttttcaa ccgggagaac
     4861 gcagatggat acgaagcacg atggcggctc gccgatcgcc gaacggcgca ccgaaggctt
     4921 tcgcttgctc gaatcgggca tgccgcaggc cgacgttgcg cgaaggctcg tcgtatcgcg
     4981 gcaatcggtc tgcagatggg cgaaacggct cgcggaacgc gacgggcgca tcgcgaaggc
     5041 gccgggacgg ccacggcggc tgaattccgt gcaatgcgcg acgcttcgcg cgatgctcga
     5101 cgacggcgcg ctcgcggcgg gcttcgcaag cccgcagtgg acgctcgcgc gagtacgcaa
     5161 gctgatcgaa cgcgaattcg gcgtcgcata cagcaagacg ggcggatggg aattgctgcg
     5221 cacgctcggc gtctcgctgc aacgaacgga aaggcatccg cacatcgcgc gctgaccggt
     5281 atccggagat tcgtgtcgac ttggtgaccc gttcgcggcg cgatcgcgcc gcaagtacat
     5341 gcctgcgtca cgcgcctatg atcggctgcc gcacgcatgc acacgccgat cgtcccgaac
     5401 gcgttttgac gacggcaaac cagggttccg tttccgcgcc gtttcggtca ctccgccccc
     5461 cctgcaccac gctgaagata acgtgccgcc ttcgatgagg ccggcacgtc gagtatttca
     5521 ttcgaatagc gcaatcagcg aaacaatggc taatatcgcc gccaacgaaa cattgatgat
     5581 gcgagacgca acggggtcgt gcaaaaaccg ggacagcgat acgcccgcca atagccagcc
     5641 gagatggatg atgacgatca ttacgctgag cagaacgatc ttggccgcgg catcgagacc
     5701 gtaatcagtc gcgacgagcg tcgttcccgc aaataccgcg ccgatcgcga tatacgcctt
     5761 cggattggcg acggccagca ggaatccccc cttgaaagcg ggagacgaga ggttttccgc
     5821 ccgcttgtcg agtggcggcg cggtggcgat cctgtacgcg agatagagga tgtagagggc
     5881 cgaaacgata ttgagaatcc tcgctgcgct cggcatcgac atcacgaatg ccgtcacgcc
     5941 cgtcgacacg agcagcaata ccgccaccgt gcccgcgatg aggccccacg catacttgag
     6001 cgaccggcgc actccgtagg acgcgcccat cgcggtcgca ctgacggtgg agggcccggg
     6061 gctgcccatc accacagccg cagcgaaaag cagggccacc agagagcgca atgtctccga
     6121 aacaaggtcg acttggttta ccatcgaagc tccagcgcgc catctttttt gaatgggtag
     6181 cttatggaag cgtcagggag gctgtcttga acgattgtgc acgcgacatc gcgcccgacc
     6241 gagatcaaat tcggatcgga tccggcgccc caggcatcga acgcgtggag gcgcacttcc
     6301 tcgatcatgc gttcacgccg catcgtcacg acacgtacgc gatcggcatc acgctctcgg
     6361 gcttgcaaac cttcggctat ctcggcgaaa tccaccactg cctgccggga cagtgccata
     6421 tcctgcaccc cgacgagttg cacgacggcc gcgcgggaac cgacgaaggc ttcggttacc
     6481 gaatcatcta cgtcgatccc gcgctcgtcc aggaagcgct cggcggccgc atgctgccgt
     6541 tcgttcgctc accgatcttc caggcacccg ccgtttccga ggcgctcgcg gccggcatct
     6601 ggaacctgga cgaggaaatc gacaacgtat cgcgcatcga catcgccgtc gccgtcgcga
     6661 acctgctgac ggccgccgcc gcgaagggca gcgcgccgaa agccggcccg ctcgcgatgg
     6721 tcgaattgac acgtatccgc gatatcatcg cctcctgtcc gcacgagccg atctcgatgg
     6781 acgcgctcga gcacgcatcg ggactcgacc gctggacgat cgcccgccag ttccgacggc
     6841 tgttcggcac gagcccgagc cgctttcgca cgcagcgaca gctcaatctc gtgcgtcggc
     6901 tattgatgga aggcgaatcg ctgtcgaccg cctccaccga cgcgggcttt tccgatcaga
     6961 gccacatgtc gcggcacttc aagagtactt acggcatcac gccgggtgcg tggatttccg
     7021 ccgtgcgcac ccggcacgcg cagcacccgt cggaccacta aacacgtccg accggacggc
     7081 ggcgaaacac cctcgcgccg ctttctttcg atcgccgtgc ccgcccaaca ggcggatatg
     7141 gcgttccgtc ccagcgctcg cgcgcatacg cggcccatcc ggccgcgccc gacaccccgc
     7201 acgccgccgg ccgcatgcct gcccggcttc gaatgaacca acccgtgagg ccattctttg
     7261 cgaaccgccc gtcattcgat atccgtcgcc cggatgcccg ccgcgttcgc ggcggatcgc
     7321 aacggcaaaa acccacaccg tccggctccg cgcgcttgcg acatgaacgc gaaagcagcg
     7381 gcccttcaca tccggcgctc gcgccgctcg ggacacagct tcggcccggc cttcaatggt
     7441 tgtgcgctca acatcccctg ccggacaagc gcgcgcggcc cgcatcgctt tagcgaatcg
     7501 cgatatccct ttccgaatcg agcgatcaac caggagtttt ccgattcgat ccccgccgaa
     7561 tttattggcc accaaaaatt caattatcca aaacccatca caaacagcac gatcaattaa
     7621 aagtttgtat tgccaatcaa tatatggacg cagtaattta aaggacctat tccaacgcat
     7681 gcatccgccc cgcgcaccgc gaacgatttg ttggcgggcc tttccccatc ggcccggcgc
     7741 tccgtttggt cgcggcgatt cgtcatgaaa tccggcagtc cccgaagcat ggcttggcgc
     7801 gtatggctcg aaatcgtaca gtgttgcctc tcgaacgcgc gcaagtggac gtggtgcagg
     7861 aacgcagcgg cgtcgtcggc gataggcgaa tatcgctcag ggtgtgcgga gaggcgactc
     7921 agggatattt gctagagcga taccatgcgg cgccgggcga gccttcgttc gtccaacgcg
     7981 tgaatctgtt cgacgacgcg accattgcat cgttcgtcga acacgatcct tattccgcgg
     8041 aactggaaag cttgtaccgt gcggtcatag acgtgccgaa aaaagcattg aaattcgctg
     8101 gacacgaaac gattcaaccc gaattcgcat cggaatgcgt gagcgagagc ggtttattga
     8161 ccgtgatgcg caatacgata ctggaatgtg gcgcaacgaa ctgtttttac cattacttcc
     8221 ggatagacga gaaaaccgga aatctgaaga atcacgaatt attgatcggc ggaacgcctg
     8281 tatggccgca ccgttatgtg catcgccatt ggtatctgaa tgatcccgcg atggcgcacg
     8341 cgcgcaacga tacgcgcccg ctgcgcgcat cgacgctcgc cccgctgccg cacgatcact
     8401 ggctgaacca gcaggcgcaa tttctcggcc tgaccagcaa tgtgtttttc cctgcgcatc
     8461 gccgcgacga cgacacgatc ggtttgttgc acgtgagctc gtcgctgccc gccgcgcaag
     8521 gcgaggaaat catctggcgc aaccggcgca cgctgcgcgg cctcgccacc gagatgctcg
     8581 aatggaaagt cacggcgcag cgcaacacgc ttgcccgcga gatgtcgctc agccatcacg
     8641 agctcgtcgc gctgcgactc gtcggcaggg gggccaacgc gcgccacgtc gccgaggaac
     8701 tgaagctgca ggagcatgcg gtctatcagc tgttcacgtc gatcaacaag aagatgaaca
     8761 gcagccacat caggacgagc gcgaacaagg cgaagcagtt cggctttctg gcggaagggt
     8821 acatctcgga ataacggagc gccatgcgcg gcgccccgcc ggctcggtcc gtctcgcggg
     8881 cgggcggccc gcgaacggct tcagtgcccc aacaccgaat aggcaagcga ccccgaaaac
     8941 gtcgcgagca cgagcgacgc gcaacgcatg aacgtcgacg tatgcgcggc ccacgatcgc
     9001 tgcgacgtca gcagcccgcc gaggctcgac cagccgacgc cgatcggcgc gagcacgatc
     9061 aggaacacga taaccgccca cccgaagtag ctgagcgagc ggaacgcctc gagcgggaac
     9121 atcgtgctcg cgaacagcag tgctttcggg ttcatcagcg tggcgacgaa cagatcgcca
     9181 aagctgatcg gccccgcgga cagctcgtga agcgcgcggc tcttcgtcca catcttgacc
     9241 gcgagccaga ggatgtacgc ggcgctcaac aacttgatcg cgccgaagag ccagggccgg
     9301 ctcgccgcca cggagagcag gaagaagccc catagcgaga tcgcgacgac atagcccagc
     9361 gcctcggcga tcacgaggtg ccaggtgccg cgcaggccga ccttcaggcc cgacgacagc
     9421 agcaacgtgt tcgtcggccc aggtacgatc agcacgagcg acacgtaaaa cgacatcttg
     9481 agcaacgcat cctgaatgag cacggcgcct cctcggttcg tcggcttcgg taaacggtag
     9541 tcatcggctc gccgacggaa ccggcgtggg cgacgtcgcg gccgacgcgc cggcgaaata
     9601 gcggttgccg ccgggcgcga gccagtccgt ccgcaccggc gtgaacacgt cgagatcgac
     9661 cgcgtcttcg aggcacagcg cgttgtgcgg cacgttcgcc gggagatgca ggatctcccc
     9721 cggcccgacc tcgatctcgt gctcgagatg ctcgccgtaa cgaaacagca ggcgcccttc
     9781 gaggatgtag gtgagctgct cgttcggatg cgagtgcgtc ccgacgaacg cgcctttctt
     9841 cagatacagc ctcgccatcg tcagcgcgtc gcccgagacg acctgccgct cgatccgctc
     9901 ggtcagcgtt tcgcgctcga tccgattcca tgcgccgaag cctcgttcat tcaaacctgt
     9961 cacgatttcc tcctcgctcg atcgtgtgaa aagcgcgcgc tcacgcggac agctcgcgaa
    10021 cgcgcacgcc gcccgttgcg cgctgcacat cccgttcgcg cgcgagacgg cttgcctctt
    10081 cgatgatgat gtcctcctgc ccggcgacga gcttgcgctc cgcaagccgc ttgtacaact
    10141 cgaattcgtt gacgccgaat tcctgcgcgg ctttctggat atgcggcacg tagccggaga
    10201 aaaggccgta cagcccgctc gcgatgttcg ccggctggat gtgcggcgtc ttcggattga
    10261 gaaacgtctc cgtgccgcgc gcgagcgtca tcacgcgctc gaacgtcgtg cgcgtgtcgt
    10321 gcccttcgcg ctccatcgcg gcgacgagcg tttcgagctg cgtattgccc gcgccggccc
    10381 cgaagccttt cacgcatgcg tcgacgatgc gcgcccccgc ttcgagcgcg acgaggctgt
    10441 tcgcgaccgc gagcccgagg ttgttgtgcg cgtgaaagcc gacgtcgatg tcgagaccgt
    10501 cgacgaggcg ctcgaccttc gcgcgcacga gcgacggcgt cgaatacccg gcgctgtcca
    10561 tcagcaccac tgcctgcgcg ccgtagcgct ccatcagctt cgcctgcgcg agcagcgcat
    10621 cgggcggcgc catgtgcgac atcatcagca cgccgaacgc cgtgcgtccg gccgcccggg
    10681 tctgctcgat gaagcgcgcc gacacgttcg cctcggtgca atgcgtcgcg acgcgcacga
    10741 catcgacgcc gatctcgagc gcaagcgaga tgtccgccgc cttgccgagc cccggaatga
    10801 aatgcacgcc gagccggctc gtgcgcagcg cggcgcgcgc ggtctcgagc atcaggcgat
    10861 cgccgatcgg cgtctgcccg agcaggcaag acgagcctcc gagaccattg ccgtggccga
    10921 cttcgacgac atcgatgccg gcttcgtcgg ccgcgcgcgc atacgcatgt atctgcgcgg
    10981 cgctcagttg gtgacgaatc gcatggttgc cgtcgcgcaa ggtcgcatcg ctgatcagta
    11041 tcattgtgtg gctcctagtc tggcggttgc gtgccgatgc gaggcgaccg cgagcgccgc
    11101 gcagttgatg atgtccagat tgcccgcgta ctcgggcaga tagtcgccgc gcccgcgcac
    11161 ggtgagaccg atcgtgatcc tcccctggct ttcgagcggc tcgacgacga gccgatagcc
    11221 gggcacgtat tcgcgcacct tctcgaccat gtcggcaacg cttgcgcgca cgcggtcgaa
    11281 atcgcgatag cgcgcgtacg catagagcgt cgtctgcatc cgcacaccgg gctcggccgg
    11341 attgatgttg aggatcgcct tcgtcttctt cgcatcgctg aatttcgcga gcgcgtactc
    11401 ggtcgtcgtc atgtattcgt cgatgttctc gcgcgtcgcg atgccggcgc tgcgcgacgc
    11461 gatcgccgac accacctcca ggtaatcgat ctcgtcgacc gcctgcttca gtgcgtacgc
    11521 gagcggcagg ctcgcctgcc cgccgcaggt gatcaggttc acgttctgct cggcgcccat
    11581 gtcgtccaga ttgatgcacg gcacgcacag gcggccgacc ttcgcgggcg tcagatcaat
    11641 cacgaacttg cccgcgtcgg agaagaagcg gttgttgacc ttgtgcgcgg cggccgatgt
    11701 cgcgtcgaac acgaggtcgt acgcatcctc gtgcgccttc agaaaatcga gaccgtcgct
    11761 cgatgtctcc acgttgcaac tgcgcgcgag ccgcagcccg tcgctgttcg cattgcgtcc
    11821 gacgacgaac ttcagatcga attgctcgga tgccttgact ttgaacatca gatcgagccc
    11881 gatgctgccc gagcccagga tcgccacccg cgtgcgcgat gacttgctct tcatgttccg
    11941 ctctcctccg tcaaatgact catgcgcgcc gccggctcgc gcatgccgtt cggctcgtcc
    12001 tgcgcggcgc gcgcgagcac gcgctcgagc tcgcggcgaa cctcggcgag cacacctgct
    12061 tcctcgccgt gcataaagaa atggccgccg gaaaagccga catagcgcac ggccccgatc
    12121 gtctcggcga gccagccgga caaaccggcg tcgctgacga ggccgtcgtt cgagccgtgc
    12181 aacaccagca tcgggcaatc gagcggcggc ggcccgacgt agcggtatgt cgccgaaatc
    12241 gtcagatccg cgcgcagcct cggcagccac agctcgcgca gcgcgggatc ggcgatcagc
    12301 gcttccggcg tgccgttgta gtcgcgcacc gcggcgatga acgcctcgtc gggcagcgtc
    12361 tgaatgcccg catcccgcca cctgaagcgc ggcgcgctgc gccccgatgc gacgaacagc
    12421 aacggctgcg cgaagccgcg cgcgcgcagc aggtgcgcga gatcgaatgc gatcagcgcg
    12481 cccatgctgt gaccgaagaa tgcgtacggc agatcgagca gcggcggcac gatatccgcg
    12541 agcgcctcga cgatcggctc cgcgtgctcg atcagcggct cgccgagccg atactcgcgg
    12601 cccggcaatt gcaccgcgac gacttcgatc caatccggca ggccgcccgg ccaggttcgg
    12661 aagatcgacg cggtcgcgcc cgcgtagtga aagcagaaga gccgcacgcg cgcgttgcgc
    12721 gcctcatgga cgatcagcca aggcgattcg gctgcggctt cgcgcgcgct catgcccgtg
    12781 ctccgtcgcg cgacggcacc gccacgggcg taagccagtt ccatttgtcc gcgtgcgtgc
    12841 cgcgcacgat gccgaagtac tgatcctgga tcgccttcgt caccgcgccg cgcttgccgc
    12901 tgccgaccgg catccggtcg accgagcgaa cgggacaaat ctcgacggcg gtgcccgtga
    12961 agaagatttc gtcggcgagg tagagcattt cgcgcggaat gctcgtttcg gtcacggtgt
    13021 agccgagatc gcgcgcgatc cggatcacgc agtggcgcgt gatgccgctc aggatgctgc
    13081 tgccgatcga cggcgtgaag atttcgttct tgtagacaag gaacacgttc tcgccgctgc
    13141 cttcgctgac gaaaccgttc gtatcgagcg cgatgccttc gctcatcccg ttctcgtgcg
    13201 cctccatcac gatcgcctga ccgttgacgt actggccgcc gatcttcgcc agcgtgcttg
    13261 ccgctcccgc gccgttgcgc cgccagctgc tcacctgcac gtcgacgcct tgctgcaacg
    13321 cctcgtcgcc gagatacgcg ccccacggtg tggtgatgag cagcgcctcg gccggacact
    13381 gtcgcgcgtc gagcccgagc gattcgcccg cgccgcgata gacgagcggc cggatgtacg
    13441 cgctgcgctg accgttcgcg cgcagcgtct cgaccgtcgc ctccatccat tgcccgacgc
    13501 tcatcggcga cgcaatccgc gcgaccttgc agctgaacag caggcgctcg aagtgctcac
    13561 ggccgcagag gatcgccgcc ttctcgccga tctcgtacgc gcgcacgcct tcgaacacac
    13621 tcgtcccgta atgcagcgca tggctcatca catgcacctg cgcatgctcc cacggcacca
    13681 gttcaccgtt cttccacacg tagctcgatt tcatcgttgt tgcgctcctc acatgacgtt
    13741 gtattgattg aatgcctcga cgacgctgcg cccctctgcg atcgcgccgc gtaccttgcg
    13801 ctcgagccgg ttcttcgcga tcgcgcgcgt gatcacctcc cgctccgcct cgcgcggaat
    13861 cacgcagacc ccgtcgccgt cgccgaaaat cagatcgccc gggcgaattc gcacgtggcc
    13921 gacggtgatc gagcagcgat agtcgacgac gttgtggcgg ccctgcagcc cgtacgcata
    13981 cgtaccgtgc gcgaacgccg gcaggttcag gtcgagaatc gcgttcgcgt cgcggacgtg
    14041 cgcgtggagc acgacgcccg ccgcgcccag attgcgcgcg cgcgtgacga gcaggtcgcc
    14101 gagccgcgca accgccgtcg ggccgccgct cgcgatgtag acttcgcctg ggcgcagcgc
    14161 ctcgaccgat tcgaacagca gtccgaacgg cttcgcgtcg tagcgcttga ggccgccgtg
    14221 cggcacgggc ggctcgtcct gcaccggcat cgcgcggccg atcatcacca tgtcccgccg
    14281 caacggccgg atctccggcg gcagcatcgg gtaggcaaac ccgagcacct ccatcacgtc
    14341 gctgacggga caggtcgaga gctcggcgcg catcagcgcg aacagctcgt catccgaatt
    14401 ccactgcgcc atttgtctgt catccgatta gagtggagct cgcgtcgctc aaaagcggct
    14461 cgagctcgcg gttgatgtgg tcgagcaccg acgcctcttc gtcgtgaatg aagaagtgat
    14521 cgccggcaaa ccggtaccgc gcgaagctgt gctgcgtctc gcccgcccag cgggcgagcc
    14581 ccgcgtcgtg cacgagcgcg tcggcggcgc cgtgaaagac gacgatccgg caatcgagcg
    14641 gcgcttgccg ctcgtaccga tacgtctcga acaccgcgcc gtccgcgcgg attcgcggca
    14701 gcagcagctc gagcagtgcc gggtcctgca ggatcgcgtc gggcgtaccg ttgcaaccgc
    14761 gcagcacttc gacgaactcc gcatccgaca atcgatgccg aatcacctcc ggcttcacgt
    14821 cgggcgcgtt ctgcgcggac gcgatcagca agcgcggctg cggatagccg cgtgcgcgca
    14881 gcacccgcgc gacctcgaag ccgatcagcg cgcccgtgct gtgcccgaag aacgcgaacg
    14941 ggcggtcgag caacggcgcg agcgcgtcga cgagcggcgg cacggcctcg tccatcgaat
    15001 acagcagcgg ctcgttcagc cggttctccc ggcccggcat ctgcaccgcg acgagctcga
    15061 catcgtccgg cagcgcctcg ccccagtggc ggaagatcga accgccgcta cccgcgtagt
    15121 gaaagcagaa cagccggatt cgcgcatcgg gtttccgttc gtcggcgccg aacaggaacc
    15181 agcgggcctc gcatgcattc atgtcggcgc cgtccatcgc ttacgcgagc gccgcgacgg
    15241 cggcgagcgg cttggtcacg cggttatggc cgtagcggtc ctcgcccgcc accagcaccg
    15301 tcgagtaacg gtcgagcggc agcacttcgc cgaagtggtg gaacgagtcc tgccccgcgt
    15361 agaccttcac gtgcgtcggc acgaagcgcg ttgcccagcc gaagcgcacc gagtccttgc
    15421 tcgtgttcgg gttcgagccg tgcatgcagc gcgacgtgaa gatgaagaac tggccgggct
    15481 tcacctccat gtgcaccgcg cgcgcttcat ccggcttcca gctcggatcg agcttcagct
    15541 tttcgtagtc gtagccgtag aagcccgatt tctggccgtc gtcgagcacg cgcttgttga
    15601 aattctccgg ctcgaacggg atgttgcgct tctcgtcgaa gaaccaggtg cgatggctgc
    15661 ccggcatcag cttcaggcag ccgttctcct tcgtcgcctc gctcatcgcg atccacgcgg
    15721 tcagctccca cggccgccct tcttccgcgg ccgtcggctc gagcttctcg gtgccttcga
    15781 actcgacgaa gctttcggcc tggtgccagt cggtgccttc gtcgcccgga tatttcggga
    15841 accactcggt gcgccagctc agcacgtccg gcccgaggat gctcgagatc cggtcgacga
    15901 tcttcggatg gctgatgatc tggttcagcg aaagcatgtc gagatggcgg tcgtagttga
    15961 gcttgctgtt cggaaacgcc gccttcgccg tgtcgagcag gtccatccgc acttcttccc
    16021 agacgcgggt catctcctcc ggctcgtaca gcgtgaacgg gccggcatag ccgttctcgt
    16081 agaagaattt cttctcggct tccgacagat gaaaacgctt ttgcatatca gttctcctaa
    16141 atatggcgta aagagccatg tcctgaaaag attccgcttg tcgcggccgc cgctcgcgcg
    16201 gctcttgcaa tgccccgcgg gatcagcccg cgaccggagc cacggcgctg ctcatttcgc
    16261 gcagcgtatc gatctcggcg ctcaacgccg cgaccgtcga gcgcgtcttg tcgaaaaaca
    16321 gtctcggcga cggcgcgacg cccgttttcg ccttgatctg cttgagcact tcgacgagat
    16381 tgagcgaatt gccgccgatg tccagaaaac gggtatcgcc ggtcaccttc ttgacgccga
    16441 tcacgctctc cagaatctga atcaacatcg tttcggtttt catgaattca cttcctcctg
    16501 gttactttcg ttgatgcgct gttgcaatat cgacagaagc gctttgcgat ccgtctttcc
    16561 cgatgacaac tgcggaaact gctcgagaac cttgacgtgg cggggcacca tgtaggcggg
    16621 cagctccgcc gcgaggcgct gcctgatttc gtcggccttg caatcggcgt cgagcggcgc
    16681 gccgcgttcg agcagcacgc cggcggcgag cagcgtctcg ccgtagcgcg attcgagcag
    16741 caccacctcc gatccgtaca cgtgcggcac gctgttgatg acccgctgga tttcgctcaa
    16801 atggatccgg tagccgccga tcttcacttc gttatccttg cggcccatgt agtagaggct
    16861 gccgtcggcg agatacgcgc agacgtcgcc cgttcgatag aacggcacgc cgtcgagacg
    16921 cacgagccgc gccgccgttt cttccggcag attccagtag ccctgcatta cctgcgtgcc
    16981 gccgatcatc aactcgcccg gcacgcccgg cgccgtgatt cggttgccgc cctcgtcgac
    17041 gagcagcgcc cgcacgtgct cgagcggctt gccgatcggg tagagcgtgc gccgctccgg
    17101 ctcgatctcg cggatcacgt gcgcggtcgc cgcgcaggtg gcttcggtcg gcccgtaggc
    17161 gttgatcacc tgcacgcccg cgctcttcct gagccagcgc tggaccgtct tcacgtcggg
    17221 cacgtcggtg ccggtgagga tcgtcttcag atgcggcagc ggcgcggatt cgaattcctc
    17281 agcttgcgca atcaggccga gcatcattcc ccacgcggaa aagtgggtga cgtcgtgcgc
    17341 gcgaatcgcg tcgaacagca gatcgggcgc gttcacgtcg tcgtgcacgt atagcgacgc
    17401 gccctgcgcg agcggaaaca gcatgtccat caggtacacg tcgaagttca gcggcgagaa
    17461 gctcgcgcag cgcgattgcg ccgtgacatc gtagacggcg cgcgtgccct cgaagaaatc
    17521 cgcgatgctg cgatgattga tcagcacgcc tttcgggcgg ccggtcgagc ccgacgtgta
    17581 gatgcagtac gcgatcgctc gctcgtcgag cggcggcagc ggtagcggct gcacgagcgc
    17641 gtcgagccgc ggcgaatcgg cgtcgtctag aagccgctcg agttcggtca cgggcacgat
    17701 cggcgcggcg gccggcagcg cgtgttcgat cgcgtcgatc agatcctcgt cggcgatcac
    17761 gagcgtcggc gcgacgtcgt gcaggatgta gcgaagacgg tcggccggca tgcgcggatc
    17821 gagcggcaca tgcacgcagc ctgccttgaa cacgccgatg atcgccgcga caagcagcgc
    17881 gcggcggctc gcgagcatca cgacgcgatc gccggggcga cagcccagat cctgcaggcg
    17941 catcgcaaaa cgcgtgctga agctgtcgag atcggcgtag ccgagatcgc cgcgggaatc
    18001 ggacaacgcg catttgtacg gcgtcgcgaa cgcgtgagac tggattgctt gaacgatgtg
    18061 tctggccatc tgactgaatc ctctttgcga tgtctcttta cgggcacctt cgagattcag
    18121 gcggcattgc gcaccggcag acggccggac ggcacggcat gcgcgttcgc gctgcacgtt
    18181 cgtccgccaa cgactaccgg cccctcgtcg tttgactgct tgctgctttc tctcagactg
    18241 ctggttgctt ttttgtatcg cccgccggta cgccgccgaa ccgcccatgg agcgggatcg
    18301 cgcggcaccc ggcgcgcaac gctcgcgaac gcgcacgagg caggctcgat acgtacggcg
    18361 cggcgtcgtc tggaatgcgc gtcgttcgtc gccgcatcca ttgattgata ggctagatga
    18421 aattctccga ggaaatactt agatcacttc cggaatatat gcccgcgatt tcaccggaaa
    18481 tgaagaataa gcaccgtaat gaaaatttaa gtgtttaatt gatatttatt tggtcgcgca
    18541 attatttttc ggtgacccaa taagtacgtc ggcgccacgt agttgcgcgg gtcatatccg
    18601 tattacgaca ggtgcaaggt cgtatcacgc ggcgtcatat ccgctctgaa cgcagccgaa
    18661 ttggctatcg aggcaaatcg agggcattcg tcgctttaac ggccaccgtt cacgcggtgc
    18721 tcgcgatgcc gcccgaagcg tttcatcgat cgacgatgaa gggtgcggcg aaatcccgtg
    18781 tcgccgcggt caaccgcgtg tctgcgcggc gacgcttcgg ccgtcttgcg cggaaaagcg
    18841 cgtacgagcc ctctccccgg catgcccgcg caaatcgtga cccgatgcgt gcgcgatgcg
    18901 gggtcgcgcg cggcgcggcc gctcgtcacg aaacaggatc ggtttgtatg gattcggcga
    18961 aacccgccgc gaaaggcgat ttcggtgcgc aacgtcgccc gccggcaatg cgtgcgatgt
    19021 tgtcgacggc acggcaggcg cgatgccggc caccaagtgt cggctgcggc tgcgcaccgg
    19081 cgcgccggcg cgccgcgtaa cgcctctagc gcgcttgacg tgcatgcaac acggcgcggg
    19141 ccctatcgcc gaatgcgcag tgctcgccgg cactggcgag cgccgcacgc attcgcccgc
    19201 ggcgccggct cgcgcgcggc ggatcattcg ttcaaccgaa cgtatcggcc agcggagcca
    19261 accgcgcctg ccgccgaaga cgacgcggtc acgccgccgt catccttcga cggcctgccg
    19321 cagccgcagc aatgcctgat cccactgccg gccgatcgca tcgagcgccg cgcgcgccgc
    19381 atcgatccgc gcgggatcga agctccagcg ccgctcgcgc ccgactttca cgtcgtgcac
    19441 gagccccgct tgcgcgagca cgagcagatg ctgcgtgacc gactggcgcg tgatgtcggt
    19501 gcccgcggtg atttgcgcga tcgacagcgc cgtgccggca cacagcgcgg cgacgatccg
    19561 cagccgcgtt tcgtcgccga gcgcggcgaa cacctccgcg caatcgcgca gttgcgcgcg
    19621 cttgagcggc gcgcgcgatg tccggccctc agcgcgcgtc gacatgggcg gcgatgttcg
    19681 tcatctgctc gccccaaccg ccgtcgttca ttcggaacgc ttcggcacgg cgctcgatcg
    19741 gcagcttgtc gaagcccgat tcgacgacgg tgagcagcgt gccgccagcg acgtcggcca
    19801 gctcgaacac gacgagcgtc ggcgtctcct gcgcgtagtc gacggccgga tcaatcgcag
    19861 cggggtgcca gtggtacgag aagcgatgtt ccggctcgat tcgctcgatg cgcatccgca
    19921 acaccagatg ctcatagccg ggatacgtga tgcggccttc gacgcaccgc cccgcttcga
    19981 acgtctgccc tgccagatcg acgcgaaacc acgcgccgaa ttcgtcggcg ttcgtcagcg
    20041 cgcgccacac gcgcgagcgc ggcgcgttca gcacgatccg cttttcgata cgatcggtcg
    20101 atgtgttcat atgcagcctc ctggctgcat attagacagc gcgtccgtga aaggcaagca
    20161 aatgcctgca tgtgcgggcg tcgcgcgcgc cggctcgcgc cgcccgcgcg tcgcgcgaga
    20221 caaatgtcgc gccacgcaag cttcgcgcat tcgcgctcag ctcagcaggc ccgccgccac
    20281 gttgaccgac agccccagca ccgccatgtt gaaatagaag gacaggatcg actgcgcgag
    20341 cgccgcgcgc cggatcgagc gcccgcgcag cgatacgtcc gccgtctgcg acgcgaccgc
    20401 gatcgtgaac gagaagtaca ggaaatccca gtaatcgggc tcgagctcgc gatcgggaaa
    20461 cgccatcgcg cgcgcctcct tcggcgacag atagtagagc cgcgcatagt gcagcgtgaa
    20521 gatcgtcgga atcaggaacc atgcgccgaa catcgtcgcg cccgtcaccg cgtagtggcc
    20581 gaggccggaa cggaacccga cgctcttcgc gctgacgagt tcgagcacga tcgccgcgat
    20641 gctcgcgacc gttgcaaaac agatgatggt cagcaccatc gtcgcgttct cgtcttcgcg
    20701 catcgcgatc tcgcgcacct tgtgatgatg cgcgcgcacc atcctcaccc acatcagcac
    20761 gagatacagc cagatcgtgc aatcccagcc gatcagcacg cgcgcgaacg gccgcagcgg
    20821 atacggaaac agcaggccta acgcgacgcc ggcggcgacc gcgatcacca tgcgcgggcg
    20881 attgcgcagc acttgcggat agaacgtcat ggtcactcgc cgaaacgatc gaaagtcggg
    20941 tgaaagaacg cgccgctgtt gcggcgcgtc gcagcgatta tcgtcacgtt ctcccgctgc
    21001 gccaagcccg gctgtgtcct aagatgggcg aatggacact gctcccctga tccgtcgcca
    21061 taccgcaaac cacgccggcc gcgatttcgt cgtcggcgat ctgcacggct gcgtcgatcc
    21121 gctgcgcgcg ctgctgcaca ccgtgcgctt cgatccggca cgcgaccggc tgttctcggt
    21181 gggcgacctc gtcgaccgcg gcgcgcaatc ggaagcggcg ctcgcgctgc tcgagcgccc
    21241 gtggtttcat tgcgtgctcg gcaaccacga agacgtgctg tgctcggtcg cggacggcaa
    21301 gctgccgatg agcgtgtggc agcgcatcgg cggcgaatgg gcggccgacc tgccggccgc
    21361 gacgctcgcg cgccatgcgc ggcggttgcg cgagttgccc ctcgtgcgcg tcgtcggcga
    21421 aggcgacgcg cgcttcaacg tgctgcacgc ggagttcttc ggcagcgacg ccgacctcga
    21481 ccgcggcgac tacgcgcccg acgtgatcac gcggctgctg tggggccgcg agctggcgta
    21541 cgggcgcacc gacccggccg cgcggcaggc cgggctgtcg accacttact gcggccatac
    21601 gccgatgcat gatgtcgtgc gcatcggcgc gcagacgttc gtcgatacgg gcgcgttcga
    21661 tccgtcgggc cggctcacgt tgctcgacgc gaagagcggc gaaagctggt cgatgtcggt
    21721 tgcggccgcg cgccaccagg gcgccgccga cgtgccgctg ccgtgacgcg cgcgagccgg
    21781 acggagccga cgcccggcgc ccaacgcgct gcgtcgagac ggcgcgcaag cgcgacggcg
    21841 gcgcaaaccg cacgccgcct cagccgacct gattcagttc gaacaccgca tcgatcgccg
    21901 cgccgttcca gttgtattcg agatacgcgg cgtggcggca atcgtgcagc aacgtcgtcc
    21961 tgaacgcggc gaggcactcg ccgcccggat cccgcaccga cgggtacgca atacctgcgc
    22021 cgcccgcatc gcgcaccgcg cggccgagcg cctggccggc cgagtaatcg acgagatcga
    22081 gcagcgccgg gtcgcgctcg cgccacgcgc gcacgtcggc gacctcgcct tgcgcggcta
    22141 ccgtgtagag gcgcatctgc tggcgcatcg gcggctcctt cgtcgcggcg agaaacagcg
    22201 acgtgtgata acgcgtctcc gcgatcgccg tattgcgcgc gcgggcgcaa tagaacacgc
    22261 cgtagctgcc gtccgaaaaa cggctgccgt tcggattcag gtgcgtgaac gcggccatga
    22321 tcggcccgta gccgggcccg aagcgccgct cctgcggcgg cacgagatcg agcatgccga
    22381 cttcggtgcg cacgcggtcg ttggtcagcg cctcgagtgc atagagcgcg tcgaaatcct
    22441 cggccgatgc gacgcggtcg aacaggttga tcgcgggaaa gcgcgtggga atcacgcgat
    22501 aggcgggcgc ccagtcgagc gacgcggtgg gccagttcgt ctgccgttcc ggagaggtca
    22561 cgcccatccg cctcgcgccg cgtcgagata ttgccgcacc gcgacgagat cgctgacgtt
    22621 gccggcgagc atccggtcga gcgcgcgctt gccgttgaac ggcgcggcgt cgttcggccg
    22681 cttgacccac gaatcggccg cggccggctg cggcagcagg atctgcagcg ccttgtagat
    22741 gccgagcacg agcgacaggc gctcgagcgt atcgtgcgtg aggcgcgcgg tttgcggcga
    22801 cgccttccat ttgaagaacg tcgaacggcc gggcgagccc agcaaaacga gctgctcatc
    22861 ggtcgacaga ttccagtcgc gcgcgatatt gaaaaatgcg cgcagaccgg ccgccgacat
    22921 ttgctcgacg gtcgccgccg gtggcgtcga aaacggcttc agggcgggac gggacatggc
    22981 ggttagtctc gaaatgaatc tactaacaag attagtccat ttcgggatct ttgcaagaaa
    23041 aaataatggc ggatccgaat aagctgcgga ttgcaatcgt tttgatgggg tcgaagtgaa
    23101 atgagttggc gagctggttt tcgggctggc gttcgagcgc aactgtccgg gctaacgcca
    23161 gcagccccct gcacggatgg catcccgcct tccctagcgt acgcctgcgg ctactccagc
    23221 cgctcatcgc gcaattgcct ccctaccttc ccgcgcatac gcggcaacgg cgcatcgccc
    23281 gcccgtcact gcgcacgcga gaaaggcaac gcgctcggca gccgggcatc ggcatgtgcc
    23341 cgcgacgcgg agaacggatg gtgcatgcat ggcagattct ttgcagtgtt ccgggtgcgc
    23401 acgaagacgg gccaaagcga tcgggcaaga aacggccgga ggggaaaccg gcgagaatcg
    23461 gatatcgcga gaccgggaag cgagcaccgc gcgcaaggcc gcgcggcagc gaatacgccc
    23521 gcccctgccc gctgcggggg cgcgcggcga atcggccgac cgccgacgcg agccgacgca
    23581 agccgtcacc gcgcggcgcg ccacgcaacc tgcgcgaccg gcctctccgt ccgcgtcgac
    23641 gcaccgtccg gcgcgccgca gtcaggcgac gcggcaccgg cgcgaacgcc gccgcccgcc
    23701 gccgtcgttt acgccggctt cgcgccgtcg agctcgacgg ccgccagctt ccgcgcttcg
    23761 cgcgcctgcg tcgcctcgac aatggcgtcg acgcgggcga gatggtgatg attgtcgtaa
    23821 tcccacggat ggaagtccgg cctgaagaag ctcagccact cgcgcgcgat cgccggaaac
    23881 atgccgtgac gcgggccgta cagcaggctg accacgcgcc agaggccgcg tacgctcttg
    23941 tccgacttgc ggtcccatcg aatcagttgc gaatggatca ggaacacgtt cggccagaac
    24001 gtcatcgtcg tcagcaaata cacgccgatg cgaatcagat agcgcttcgg cccaggcttc
    24061 atcaccgtgt tccagacatc gaacgacacc gccttgtgct cggtttcctc gagcgcgtgc
    24121 cacagccaca tctgcttgta gccttcgtgc gaaccggcga gcgcggcggg ctcgctcagc
    24181 agccagttgg ccagcatcgc cgtgtagtgc tcggccgcga ccgtatgcgc gagctgcacc
    24241 gaatgcggca gcaccttctt catccagccc gtgactttcc acacgcgcct gtcgaccgtg
    24301 cgcgccggca gccggttcgc gtgcatcaat tcgttgtact cgacatgctc gcgcgtgtgc
    24361 atcgcctcct ggccgatgaa gccgagcacc tgtttcttca gcaccggatc gtcgatccgg
    24421 tcgcgatagt tgcgcaccga atccatgaaa aagcgctcgc ccgcgggaaa cagcagcgat
    24481 agcgcgttga agaagtgcga aacttgcgag ccctgcccgt gccaatccgt cgcgcgctcg
    24541 acgggcaagt tgaagcgcag atcgcggcgc acgggcatca cggacaccgg gtccgtcgac
    24601 ttcgcgggtt gattcatcga tgtctcctgt ctgggtggtg gcgggcaacg tccgcgaagg
    24661 tccgcgcgag cggcacgcgg cacgcaaacc ggttgcggcg catgccggcc gggcgttcgc
    24721 gcggtccgac gtttcggcgc cgtcgcgctt gcacgggcac cgcgcgcaga aggcgccgcc
    24781 cggcctcgcg ccggccgctc gcgctcgcgc tcgcagcctg gccgccgacc tttacattaa
    24841 taactgaaac aatatggcga cggaccgggg ttaagcaagg cgcgtgttag tggcggcctt
    24901 ccaaacgcgc ggcgcgcggc aagcgccgcg cggcgaaccc gcaagccccg cgcgacgggc
    24961 gtttcggcgt gatcgcgcca atcggcgtct gtcttgcaaa cgcccatcgc cgagcgtttt
    25021 cccacggcat cggccgacgc cgcgaaaccg gcgcgccggg aaatccggtc gagatcgcgc
    25081 ggctccccta caatagcggg tcatttcgat ccttcaggag catttcatga cagtcgtcac
    25141 caccgaatcg ggcctcaaat acgaagacct gaccgaaggc tcgggcgccg aggcgcgcgc
    25201 gggccagacg gtgagcgtgc actacacggg ctggctcacc gacggccaga agttcgattc
    25261 gagcaaggat cgcaatgatc cgttcgcgtt cgtgctcggc ggcggcatgg tcatcaaggg
    25321 gtgggacgaa ggcgtgcaag ggatgaaggt gggcggcgtg cgccgtctga cgatcccgcc
    25381 gcaactcggc tacggcgcgc gcggcgcggg cggcgtgatt ccgcccaatg cgacgctcgt
    25441 gttcgaagtc gaactgctcg acgtctgagc ccggcgccgc cccgccgccc gtcgccccgt
    25501 cgcgcgcgtt caccggccgc ccgcccgatc atgacccgcc tcgccgcccc gagcctgtcg
    25561 ctgcgccgtt acggcgccgt gcaggcgtcg gacgtgcacg atttccatca gatcgtgctc
    25621 ggcgtcgacg gcgcgatgac gatgacggtc gacggcgtcg acgagcggat cgaccgccgc
    25681 tgcgcgtggc tgattccggc cggcgcgcgg cacgattacg cgggcctcgc cgacaacagc
    25741 caactggtgc tcgacttgcc gcccggctcg ctcgcggtgc ccgagcggct gttcgagcgc
    25801 gccaggacga tggcgatcga cccgggcctc acgacgctcg tcggcgaact cgcgtcgcgc
    25861 atcgcgcgcg ggccgctcgc cgatgccgcc tcggcccggc gcctgcactg gcaagcggcc
    25921 gcacggctat gcggcgcgct cgtcggcgag ctgggcggcg cgccgtcgca gcccgccgtc
    25981 gggctcgact tcgcacgcat cgacggctgg ctgcgcgcgc acctcgcgca gccgctgcgc
    26041 atcgccgatc tcgccgcgca ttgcggcttc ggcatgcgcc gcttccatca gcttttctgc
    26101 gaagcgttcg gcgagacgcc gcatcgctat ctgcagcggt tgcggctcga cgccgccgtc
    26161 atgttgctcg gggatccgaa acattcgctg accgacatcg cgagcgaagt cggattcgcc
    26221 gaccagagcg cgttcacgca cgcgttcacg aaacggttcg ggctcgcgcc cggccgctgg
    26281 cgcagcgatc ggcactgagc tttccgatgc gcgcgagcgg gccgacatcg cacgcgacgt
    26341 gaagcaccga cgccgcgacg atgcaacgac gcgacgactc gaagaaagcg ccccatctcg
    26401 cattcgccac cgcctcgcac gctcgcgtgc gcctcgcacg ttgcgccggg gcggccgcgc
    26461 cgggccgggc gcgtcgcggc aatcccgtcg ggtaacgtga aagcgcgcgg cgccgcccgg
    26521 cgcgccaggc ccggcgcccc gcacgcgatt cgcgggacac cgagcccgcc gtgcccgccg
    26581 catcggtcaa acggcggccc gaatcgcctc ctcgtagacc gccgcgacgc ggcgcgcgat
    26641 caccgtgttg tcgaaatgcg cgcgcgcgta tcgccggcat gcgtccgcat ccggcagcac
    26701 gagcgagccg gacaacgccg cggccaaccc gtccgcgatc gcggccgcgc ccacctccgg
    26761 cagcacgagc gcctccgaca ggcccgcgac cgcctccggc agcccgccga cgggcgtcac
    26821 gagcaccggc gtgccggacg cgagcgactc gacggtgatg agcccgaatc cctcgagcgc
    26881 gacggtcggc acgacgctga gcgtcgccgc acggtacagc gcggccagat gattgtcggg
    26941 cacgaaaccg agcagcttca cgttctcgcc gagctcggcg tcgtcgatcc gtttgcgcag
    27001 ctcgccttcg agccgcccct tgccggcgat cagcagcagc acgtccggat gccggcggcg
    27061 cacggtcttc accgcgtcga tcagatcctc gagccccatg cgccgcacga gccgccgcac
    27121 cgcgagcacg atcggccgat cctgcggcag ttgcagcttg cggcgcgcgt cggcgggcgt
    27181 catcggcaga tcgaattgcg cggtgtcgac gcagccgggc acgacgcgca cgcgcgccgg
    27241 atcgacgttg tagcgcgacg tgagaatctg cccgaacgcg tgcgacagca cgatgagccg
    27301 cgacgagcgg gcatagaccg cctgctcgag ccggtgcttg accttctgcc cgagcgaatc
    27361 cgcgccctcg acgtggctct cgtcggccca cgggccctgg aaatgcgaca cctgcggaat
    27421 gccgcgcgtc acgtcgagcc cagggaacgt gtacagcgcg aagtgcgacg acacgacgtc
    27481 gggccgctcg atgcgcatca cgtcgcgcag cgcatggcgc gcggcgatca tccgccgcgg
    27541 caacgacgac gtcgccggcc cgaagccgcg gatcgcgccg cccgtgtcgg ccgcgacgcg
    27601 ctcggagccc gcgaccacgc cgcgcaccgc gacgcccgcg ctcggcagcg cgccaacgag
    27661 cgagtaatac atgcgatcga gcccgcccgc tcgctcggga aaccagtgca tgccgatctg
    27721 cagcgacttg atcgacgttt cggtatgctt cattacgacc gctcctgcgt cacgacatgc
    27781 tcggtgccgg cgagcggcga cggctgcgac gactggcgca gccgccgata caatgcgatg
    27841 tactgcgcgc ccatgcgcgc ccatccgaat ccctccatca gcctgcgggc cgcctcgccc
    27901 atcgcgcggc acgcgtcgcg cgagcgcgcg aggcgctcga tcgcggccgc gagcgcggcc
    27961 ggatcgtcgg gatcgtcgag cacgatcccg cactccggcg tgatgatctc cgcgccgccc
    28021 gcggtgcgcg cggtcacgac gggcagcccc gccgccatcg cctcgagca
//
