GCF_017356505.1 - 10 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_VOEC01000011.1 (Enterococcus hirae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 3.1	terpene-precursor	160,137	181,021
Region 3.2	RiPP-like	234,513	247,695

NZ_VOEC01000013.1 (Enterococcus hirae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 5.1	cyclic-lactone-autoinducer	1	16,758

NZ_VOEC01000022.1 (Enterococcus hirae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 15.1	terpene	66,142	87,011
Region 15.2	lanthipeptide-class-ii	103,921	126,824

NZ_VOEC01000024.1 (Enterococcus hirae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 17.1	cyclic-lactone-autoinducer	46,857	67,595

NZ_VOEC01000028.1 (Enterococcus hirae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 21.1	RiPP-like	1	6,799

NZ_VOEC01000004.1 (Enterococcus hirae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 34.1	RiPP-like	10,278	20,493
Region 34.2	T3PKS	42,708	83,859

NZ_VOEC01000063.1 (Enterococcus hirae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 60.1	cyclic-lactone-autoinducer	1	6,659

Region	Type	From	To	Most similar known cluster
Region 3.1	terpene-precursor	160,137	181,021
Region 3.2	RiPP-like	234,513	247,695
Region 5.1	cyclic-lactone-autoinducer	1	16,758
Region 15.1	terpene	66,142	87,011
Region 15.2	lanthipeptide-class-ii	103,921	126,824
Region 17.1	cyclic-lactone-autoinducer	46,857	67,595
Region 21.1	RiPP-like	1	6,799
Region 34.1	RiPP-like	10,278	20,493
Region 34.2	T3PKS	42,708	83,859
Region 60.1	cyclic-lactone-autoinducer	1	6,659

No secondary metabolite regions were found in these records:: NZ_VOEC01000001.1 (Enterococcus hirae); NZ_VOEC01000010.1 (Enterococcus hirae); NZ_VOEC01000012.1 (Enterococcus hirae); NZ_VOEC01000014.1 (Enterococcus hirae); NZ_VOEC01000015.1 (Enterococcus hirae); NZ_VOEC01000016.1 (Enterococcus hirae); NZ_VOEC01000017.1 (Enterococcus hirae); NZ_VOEC01000018.1 (Enterococcus hirae); NZ_VOEC01000019.1 (Enterococcus hirae); NZ_VOEC01000002.1 (Enterococcus hirae); NZ_VOEC01000020.1 (Enterococcus hirae); NZ_VOEC01000021.1 (Enterococcus hirae); NZ_VOEC01000023.1 (Enterococcus hirae); NZ_VOEC01000025.1 (Enterococcus hirae); NZ_VOEC01000026.1 (Enterococcus hirae); NZ_VOEC01000027.1 (Enterococcus hirae); NZ_VOEC01000029.1 (Enterococcus hirae); NZ_VOEC01000003.1 (Enterococcus hirae); NZ_VOEC01000030.1 (Enterococcus hirae); NZ_VOEC01000031.1 (Enterococcus hirae); NZ_VOEC01000032.1 (Enterococcus hirae); NZ_VOEC01000033.1 (Enterococcus hirae); NZ_VOEC01000034.1 (Enterococcus hirae); NZ_VOEC01000035.1 (Enterococcus hirae); NZ_VOEC01000036.1 (Enterococcus hirae); NZ_VOEC01000037.1 (Enterococcus hirae); NZ_VOEC01000038.1 (Enterococcus hirae); NZ_VOEC01000039.1 (Enterococcus hirae); NZ_VOEC01000040.1 (Enterococcus hirae); NZ_VOEC01000041.1 (Enterococcus hirae); NZ_VOEC01000042.1 (Enterococcus hirae); NZ_VOEC01000043.1 (Enterococcus hirae); NZ_VOEC01000044.1 (Enterococcus hirae); NZ_VOEC01000045.1 (Enterococcus hirae); NZ_VOEC01000046.1 (Enterococcus hirae); NZ_VOEC01000047.1 (Enterococcus hirae); NZ_VOEC01000048.1 (Enterococcus hirae); NZ_VOEC01000049.1 (Enterococcus hirae); NZ_VOEC01000005.1 (Enterococcus hirae); NZ_VOEC01000050.1 (Enterococcus hirae); NZ_VOEC01000051.1 (Enterococcus hirae); NZ_VOEC01000052.1 (Enterococcus hirae); NZ_VOEC01000053.1 (Enterococcus hirae); NZ_VOEC01000054.1 (Enterococcus hirae); NZ_VOEC01000055.1 (Enterococcus hirae); NZ_VOEC01000056.1 (Enterococcus hirae); NZ_VOEC01000057.1 (Enterococcus hirae); NZ_VOEC01000058.1 (Enterococcus hirae); NZ_VOEC01000059.1 (Enterococcus hirae); NZ_VOEC01000006.1 (Enterococcus hirae); NZ_VOEC01000060.1 (Enterococcus hirae); NZ_VOEC01000061.1 (Enterococcus hirae); NZ_VOEC01000062.1 (Enterococcus hirae); NZ_VOEC01000007.1 (Enterococcus hirae); NZ_VOEC01000008.1 (Enterococcus hirae); NZ_VOEC01000009.1 (Enterococcus hirae)

Compact view

NZ_VOEC01000011.1 - Region 1 - terpene-precursor

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Location: 160,137 - 181,021 nt. (total: 20,885 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: peptidase

FQT05_RS06595: methionine aminopeptidase

smcogs: SMCOG1172: methionine aminopeptidase

Ligases: synthetase

FQT05_RS06565: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.39	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0000639.3	0.34	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.34	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001605.3	0.32	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000633.3	0.31	terpene	carotenoid	Streptomyces avermitilis
BGC0001227.3	0.31	terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0002181.3	0.31	terpene	pleuromutilin	Rhodocybe pseudopiperita
BGC0000648.3	0.31	terpene	carotenoid	Myxococcus xanthus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.39	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0000639.3	0.34	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.34	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001605.3	0.32	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000633.3	0.31	terpene	carotenoid	Streptomyces avermitilis
BGC0001227.3	0.31	terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0002181.3	0.31	terpene	pleuromutilin	Rhodocybe pseudopiperita
BGC0000648.3	0.31	terpene	carotenoid	Myxococcus xanthus

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

FQT05_RS06565: PT_FPPS_like

Domain 1 (30 - 277): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: IPP, DMAPP → FPP

Transcription Factor Binding Sites

Binding sites found:

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 17.31 out of 18.46

Confidence: strong

Additional weak hits (3):

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.36 out of 30.25

Confidence: weak

DmdR1

Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 22.83 out of 36.53

Confidence: weak

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 22.88 out of 30.98

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
RpoN	Regulator of nitrogen assimilation and virulence

NZ_VOEC01000011.1 - Region 2 - RiPP-like

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Location: 234,513 - 247,695 nt. (total: 13,183 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000617.5	0.49	ribosomal	coagulin	Bacillus coagulans
BGC0002579.2	0.48	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000619.3	0.45	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001388.3	0.45	ribosomal	gassericin E	Lactobacillus gasseri
BGC0001602.3	0.45	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0002577.2	0.44	ribosomal	lactococcin G	Lactococcus lactis
BGC0000624.3	0.43	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0002674.2	0.42	ribosomal	enterocin F4-9	Enterococcus faecalis
BGC0001863.4	0.40	ribosomal, terpene	bacillicn CER074	Bacillus mycoides
BGC0001861.4	0.39	ribosomal	bacillicin BAG2O	Bacillus cereus BAG2O-1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000617.5	0.49	ribosomal	coagulin	Bacillus coagulans
BGC0002579.2	0.48	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000619.3	0.45	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001388.3	0.45	ribosomal	gassericin E	Lactobacillus gasseri
BGC0001602.3	0.45	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0002577.2	0.44	ribosomal	lactococcin G	Lactococcus lactis
BGC0000624.3	0.43	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0002674.2	0.42	ribosomal	enterocin F4-9	Enterococcus faecalis
BGC0001863.4	0.40	ribosomal, terpene	bacillicn CER074	Bacillus mycoides
BGC0001861.4	0.39	ribosomal	bacillicin BAG2O	Bacillus cereus BAG2O-1

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 20.54 out of 26.33

Confidence: medium

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.40 out of 19.26

Confidence: medium

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.58 out of 21.84

Confidence: medium

BldD

Description: Development and antibiotic global regulator
Species: Streptomyces coelicolor
Score: 20.74 out of 23.43

Confidence: medium

BldD

Description: Development and antibiotic global regulator
Species: Streptomyces coelicolor
Score: 20.04 out of 23.43

Confidence: medium

Additional weak hits (3):

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 15.78 out of 18.46

Confidence: weak

MatP

Description: Cell cycle regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.27 out of 25.75

Confidence: weak

MatP

Description: Cell cycle regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.11 out of 25.75

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
ANR	Anaerobic transcriptional regulator
BldD	Development and antibiotic global regulator
CRP	Cyclic AMP receptor protein
MexT	Global virulence regulator
ToxT	Regulator of MSHA biosynthesis

NZ_VOEC01000013.1 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 16,758 nt. (total: 16,758 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001291.3	0.41	ribosomal	enterocin NKR-5-3B	Enterococcus faecium
BGC0000494.5	0.40	ribosomal	uberolysin	Streptococcus uberis
BGC0000540.5	0.32	ribosomal	paenibacillin	Paenibacillus polymyxa OSY-DF
BGC0002579.2	0.31	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000624.3	0.31	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0002667.2	0.27	ribosomal	estericin A	Clostridium estertheticum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001291.3	0.41	ribosomal	enterocin NKR-5-3B	Enterococcus faecium
BGC0000494.5	0.40	ribosomal	uberolysin	Streptococcus uberis
BGC0000540.5	0.32	ribosomal	paenibacillin	Paenibacillus polymyxa OSY-DF
BGC0002579.2	0.31	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000624.3	0.31	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0002667.2	0.27	ribosomal	estericin A	Clostridium estertheticum

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.00 out of 27.78

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.90 out of 27.78

Confidence: medium

Additional weak hits (1):

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.58 out of 19.52

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria

NZ_VOEC01000022.1 - Region 1 - terpene

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Location: 66,142 - 87,011 nt. (total: 20,870 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

FQT05_RS10655: dehydrogenase

smcogs: SMCOG1222: dehydrogenase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.3	0.57	terpene	carotenoid	Rhodobacter sphaeroides
BGC0000656.5	0.47	terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000646.5	0.45	terpene	β-carotein	uncultured bacterium
BGC0000645.3	0.45	terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000664.5	0.43	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002306.2	0.42	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0001226.4	0.42	ribosomal	streptocollin	Streptomyces collinus Tu 365
BGC0000563.4	0.42	ribosomal	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0000648.3	0.42	terpene	carotenoid	Myxococcus xanthus
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.3	0.57	terpene	carotenoid	Rhodobacter sphaeroides
BGC0000656.5	0.47	terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000646.5	0.45	terpene	β-carotein	uncultured bacterium
BGC0000645.3	0.45	terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000664.5	0.43	terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002306.2	0.42	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0001226.4	0.42	ribosomal	streptocollin	Streptomyces collinus Tu 365
BGC0000563.4	0.42	ribosomal	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0000648.3	0.42	terpene	carotenoid	Myxococcus xanthus
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
triterpene	C30 carotenoid	diapophytoene	C30	acyclic	none

Genes with terpene domains:

FQT05_RS10660: PT_phytoene_like

Domain 1 (15 - 284): Prenyltransferase; Phytoene synthase like

Subtype: Diapophytoene synthase

Reactions:: FPP → diapophytoene

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.52 out of 27.78

Confidence: medium

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.73 out of 29.25

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.71 out of 26.06

Confidence: medium

Additional weak hits (1):

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 25.11 out of 36.54

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
FPP	Farnesyl diphosphate

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
MogR	Repressor of flagellar motility genes
SypG	Regulator of biofilm formation and host colonization
ToxT	Regulator of MSHA biosynthesis

NZ_VOEC01000022.1 - Region 2 - lanthipeptide-class-ii

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Location: 103,921 - 126,824 nt. (total: 22,904 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Lyases: cyclase

FQT05_RS10835: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002701.2	0.54	ribosomal	paenithipeptin	Paenibacillus thiaminolyticus
BGC0000525.5	0.50	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0001579.4	0.49	ribosomal	duramycin	Streptomyces cinnamoneus
BGC0001210.5	0.45	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000500.5	0.45	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000503.5	0.43	ribosomal	cinnamycin	Streptomyces cinnamoneus
BGC0001407.5	0.43	ribosomal	bicereucin	Bacillus cereus SJ1
BGC0002346.3	0.41	ribosomal	kyamicin	Saccharopolyspora sp.
BGC0000527.5	0.40	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0001391.3	0.40	ribosomal	thusin	Bacillus thuringiensis serovar rongseni

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002701.2	0.54	ribosomal	paenithipeptin	Paenibacillus thiaminolyticus
BGC0000525.5	0.50	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0001579.4	0.49	ribosomal	duramycin	Streptomyces cinnamoneus
BGC0001210.5	0.45	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000500.5	0.45	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000503.5	0.43	ribosomal	cinnamycin	Streptomyces cinnamoneus
BGC0001407.5	0.43	ribosomal	bicereucin	Bacillus cereus SJ1
BGC0002346.3	0.41	ribosomal	kyamicin	Saccharopolyspora sp.
BGC0000527.5	0.40	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0001391.3	0.40	ribosomal	thusin	Bacillus thuringiensis serovar rongseni

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for FQT05_RS10835

FQT05_RS10840

Leader:

MAVGLLMKAGNVSEELAVLNNEHSLNASLDTICGT

Core:

MGSLGCGSFGCGSLSSCC

Core with dehydrations:

MGDhaLGCysGDhaFGCysGDhaLDhaDhaCysCys

antiSMASH-DB 4.0 matches for FQT05_RS10840

100.0%

NZ_CP015516.1and 17 others:

NZ_CP042289.1 Lanthipeptides: FQ488_RS12920_lanthipeptideNZ_CP055229.1 Lanthipeptides: HU262_RS11215_lanthipeptideNZ_CP055230.1 Lanthipeptides: HU257_RS11425_lanthipeptideNZ_CP055231.1 Lanthipeptides: HU256_RS12760_lanthipeptideNZ_CP055232.1 Lanthipeptides: HU255_RS11775_lanthipeptideNZ_CP065992.1 Lanthipeptides: I6I14_RS05325_lanthipeptideNZ_CP093926.1 Lanthipeptides: MOW07_RS07760_lanthipeptideNZ_JABXFL010000001.1 Lanthipeptides: HWD67_RS12585_lanthipeptideNZ_JABXFM010000002.1 Lanthipeptides: HWD72_RS00380_lanthipeptideNZ_JABXFU010000006.1 Lanthipeptides: HWD73_RS05965_lanthipeptideNZ_JAHENG010000004.1 Lanthipeptides: J8N11_RS03205_lanthipeptideNZ_JAHXOF010000007.1 Lanthipeptides: KZX57_RS09155_lanthipeptideNZ_KB932612.1 Lanthipeptides: SE1_RS18005_lanthipeptideNZ_KZ846603.1 Lanthipeptides: EA74_RS15100_lanthipeptideNZ_VOEC01000022.1 Lanthipeptides: FQT05_RS10840_lanthipeptideNZ_VOEE01000005.1 Lanthipeptides: FQT07_RS03855_lanthipeptideNZ_VOEG01000010.1 Lanthipeptides: FQT09_RS11845_lanthipeptide

Lanthipeptides: A6P53_RS13835_lanthipeptide

1

MGSLGCGSFGCGSLSSCC

18

MGSLGCGSFGCGSLSSCC

1

MGSLGCGSFGCGSLSSCC

18

61.1%

NZ_LR134297.1:

Lanthipeptides: EL114_RS12955_lanthipeptide

7

GSFGCGSLSSCC

18

GS GCGSLSSCC

2

GSLGCGSLSSCC

13

33.3%

NZ_PDKQ02000037.1:

Lanthipeptides: allorf_31549_31659_lanthipeptide

1

MGSLGCGSFGCGSLS

15

MG +G G CG LS

6

MGPIGIGDAPCGRLS

20

with 2 more sequence matches

30.0%

NZ_CP028826.1:

Lanthipeptides: DBV33_RS28695_lanthipeptide

4

LGCGSFGCGSLSSC

17

+ CG+ GC L+ C

7

IQCGTLGCTVLACC

20

15.4%

NZ_CABVIY010000009.1:

Lanthipeptides: F8N66_RS31570_lanthipeptide

3

SLGCGSFGCGSLSSCC

18

++GC + C L CC

22

TVGCPTVACTVLQPCC

37

allorf_125681_125830

Leader:

MLLLVVVVFLSKISQRIPKIGETIFGF

Core:

SGLFLRAGHFCHNLFQLLLIGK

Core with dehydrations:

DhaGLFLRAGHFCysHNLFQLLLIGK

antiSMASH-DB 4.0 matches for allorf_125681_125830

100.0%

NZ_CP042289.1and 13 others:

NZ_CP055231.1 Lanthipeptides: allorf_2676924_2677073_lanthipeptideNZ_CP055232.1 Lanthipeptides: allorf_2583654_2583803_lanthipeptideNZ_CP065992.1 Lanthipeptides: allorf_1149357_1149506_lanthipeptideNZ_CP093926.1 Lanthipeptides: allorf_1615586_1615735_lanthipeptideNZ_JABXFL010000001.1 Lanthipeptides: allorf_2753501_2753650_lanthipeptideNZ_JABXFU010000006.1 Lanthipeptides: allorf_1215526_1215675_lanthipeptideNZ_JAHENG010000004.1 Lanthipeptides: allorf_126203_126352_lanthipeptideNZ_KB932612.1 Lanthipeptides: allorf_045411_045560_lanthipeptideNZ_KZ846603.1 Lanthipeptides: allorf_046792_046941_lanthipeptideNZ_LR134297.1 Lanthipeptides: allorf_0210505_0210654_lanthipeptideNZ_VOEC01000022.1 Lanthipeptides: allorf_125681_125830_lanthipeptideNZ_VOEE01000005.1 Lanthipeptides: allorf_44991_45140_lanthipeptideNZ_VOEG01000010.1 Lanthipeptides: allorf_045441_045590_lanthipeptide

Lanthipeptides: allorf_2740138_2740287_lanthipeptide

1

SGLFLRAGHFCHNLFQLLLIGK

22

SGLFLRAGHFCHNLFQLLLIGK

1

SGLFLRAGHFCHNLFQLLLIGK

22

95.5%

NZ_CP055229.1:

Lanthipeptides: allorf_2402172_2402321_lanthipeptide

1

SGLFLRAGHFCHNLFQLLLIGK

22

SGLFLRA HFCHNLFQLLLIGK

1

SGLFLRAEHFCHNLFQLLLIGK

22

40.9%

NZ_NGKX01000001.1:

Lanthipeptides: allorf_2204162_2204308_lanthipeptide

1

SGLFLRAGHFCHNLFQLL

18

S L L FC NLF L

5

SPLLLGVKRFCSNLFSFL

22

with 3 more sequence matches

29.6%

NZ_CP046304.1:

Lanthipeptides: FOC54_RS00030_lanthipeptide

1

SGLFLRAGHFCH-NLFQLLLI

20

SG+ H CH N FQ +

4

SGVIPTVSHDCHMNTFQFMFT

24

29.6%

NZ_CP051645.1and 2 others:

NZ_JAKVFF010000018.1 Lanthipeptides: MKR34_RS11425_lanthipeptideNZ_VDOJ01000018.1 Lanthipeptides: FSV48_RS11975_lanthipeptide

Lanthipeptides: HHJ99_RS13350_lanthipeptide

1

SGLFLRAGHFCH-NLFQLLL

19

SG+ H CH N FQ +

4

SGVIPTVSHDCHMNSFQFVF

23

16.0%

NZ_VLKB01000010.1:

Lanthipeptides: allorf_1587925_1588122_lanthipeptide

8

GHFCHNLFQLLLIGK

22

GH LF+LLL K

6

GHVVPELFKLLLDQK

20

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.56 out of 30.25

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.59 out of 24.78

Confidence: medium

Additional weak hits (3):

DmdR1

Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 23.10 out of 36.53

Confidence: weak

DasR

Description: N-acetylglucosamine dependent repressor
Species: Streptomyces coelicolor
Score: 20.99 out of 27.04

Confidence: weak

NrdR

Description: Represses ribonucleotide reductase encoding genes
Species: Streptomyces coelicolor
Score: 21.59 out of 27.18

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

FQT05_RS10840 - Class II

Cleavage pHMM score: -5.10

RODEO score: 0

Monoisotopic mass: 1564.6 Da

Molecular weight: 1565.8 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 1583.8 Da N = 1

allorf_125681_125830 - Class II

Cleavage pHMM score: -6.00

RODEO score: 0

Monoisotopic mass: 2465.4 Da

Molecular weight: 2466.9 Da

Number of bridges: 1

TFBS definitions

Regulator	Description
ColR	Phenol-responsive regulator
LexA variant 2	Repressor of DNA damage response

NZ_VOEC01000024.1 - Region 1 - cyclic-lactone-autoinducer

Download region GenBank file

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Location: 46,857 - 67,595 nt. (total: 20,739 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Ligases: synthase

FQT05_RS12260: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs: SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001361.3	0.44	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002283.2	0.44	terpene	sodorifen	Serratia plymuthica
BGC0001291.3	0.41	ribosomal	enterocin NKR-5-3B	Enterococcus faecium
BGC0002579.2	0.39	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000665.5	0.35	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0002667.2	0.34	ribosomal	estericin A	Clostridium estertheticum
BGC0000666.5	0.32	terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0000663.5	0.32	terpene	hopene	Streptomyces coelicolor A3(2)
BGC0001594.3	0.31	other (other)	fischerindole L	Fischerella muscicola UTEX 1829
BGC0000668.5	0.31	other (other), terpene	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001361.3	0.44	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002283.2	0.44	terpene	sodorifen	Serratia plymuthica
BGC0001291.3	0.41	ribosomal	enterocin NKR-5-3B	Enterococcus faecium
BGC0002579.2	0.39	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000665.5	0.35	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0002667.2	0.34	ribosomal	estericin A	Clostridium estertheticum
BGC0000666.5	0.32	terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0000663.5	0.32	terpene	hopene	Streptomyces coelicolor A3(2)
BGC0001594.3	0.31	other (other)	fischerindole L	Fischerella muscicola UTEX 1829
BGC0000668.5	0.31	other (other), terpene	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 17.11 out of 19.52

Confidence: medium

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 24.68 out of 28.14

Confidence: medium

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.45 out of 25.88

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 20.12 out of 24.78

Confidence: medium

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 21.17 out of 25.88

Confidence: medium

Additional weak hits (2):

NtrC

Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 20.84 out of 29.72

Confidence: weak

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 18.65 out of 30.11

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
AfsQ1	Two-component system AfsQ1-Q2, activator of antibiotic production
LexA variant 2	Repressor of DNA damage response
PerR	Peroxide regulator
PsrA	Oleic acid responsive regulator

NZ_VOEC01000028.1 - Region 1 - RiPP-like

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Location: 1 - 6,799 nt. (total: 6,799 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002586.2	0.35	ribosomal	ASM1	Lactiplantibacillus plantarum
BGC0000487.5	0.32	ribosomal	carnocyclin	Carnobacterium maltaromaticum
BGC0000626.3	0.31	ribosomal	thuricin	Bacillus thuringiensis
BGC0001229.4	0.28	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0002110.3	0.27	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000526.5	0.25	ribosomal	macedocin	Streptococcus macedonicus
BGC0000326.5	0.19	NRPS	isocomplestatin	Streptomyces lavendulae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002586.2	0.35	ribosomal	ASM1	Lactiplantibacillus plantarum
BGC0000487.5	0.32	ribosomal	carnocyclin	Carnobacterium maltaromaticum
BGC0000626.3	0.31	ribosomal	thuricin	Bacillus thuringiensis
BGC0001229.4	0.28	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0002110.3	0.27	ribosomal	birimositide	Streptomyces rimosus subsp. rimosus WC-3908
BGC0000526.5	0.25	ribosomal	macedocin	Streptococcus macedonicus
BGC0000326.5	0.19	NRPS	isocomplestatin	Streptomyces lavendulae

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (3):

NtrC

Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 19.42 out of 29.72

Confidence: weak

DosR

Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 19.45 out of 29.51

Confidence: weak

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 22.53 out of 33.73

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description

NZ_VOEC01000004.1 - Region 1 - RiPP-like

Download region GenBank file

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Location: 10,278 - 20,493 nt. (total: 10,216 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	RiPP-like	Similarity score	Type	Compound(s)	Organism
BGC0000509.4		0.22	ribosomal	epilancin 15x	Staphylococcus epidermidis

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0000509.4		0.22	ribosomal	epilancin 15x	Staphylococcus epidermidis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.92 out of 26.06

Confidence: medium

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.98 out of 20.97

Confidence: strong

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.20 out of 23.79

Confidence: medium

Additional weak hits (3):

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 24.81 out of 31.73

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.82 out of 29.65

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.67 out of 29.65

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CcpA	Catabolite control protein A
IolR	Regulator of the inositol catabolism
MogR	Repressor of flagellar motility genes

NZ_VOEC01000004.1 - Region 2 - T3PKS

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Location: 42,708 - 83,859 nt. (total: 41,152 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidoreductase

FQT05_RS02950: aldo/keto reductase family oxidoreductase

smcogs: SMCOG1039: aldo/keto reductase family oxidoreductase

Transferases: acetyltransferase

FQT05_RS15285: acetyl-CoA acetyltransferase

smcogs: SMCOG1124: acetyl-CoA acetyltransferase

Hydrolases: back translocase hydrolase

FQT05_RS02970: GTP-binding protein LepA

smcogs: SMCOG1190: GTP-binding protein LepA

FQT05_RS02980: alpha/beta hydrolase fold protein

smcogs: SMCOG1036: alpha/beta hydrolase fold protein

Ligases: synthase

FQT05_RS02915: hydroxymethylglutaryl-CoA synthase

smcogs: SMCOG1043: hydroxymethylglutaryl-CoA synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000866.5	0.51	other (other)	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000867.3	0.49	other (other)	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000255.5	0.41	PKS	pederin	Uncultured bacterium
BGC0002561.3	0.40	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0001080.5	0.37	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000286.3	0.36	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0002707.2	0.35	terpene	(+)-δ-cadinol	Coniophora puteana RWD-64-598 SS2
BGC0002363.3	0.35	ribosomal	berninamycin K, berninamycin J, berninamycin A, berninamycin B	Streptomyces sp.
BGC0000615.4	0.33	ribosomal	TP-1161	Nocardiopsis sp. TFS65-07
BGC0002220.2	0.33	terpene	Ent-kauren-16alpha-ol	Punctularia strigosozonata HHB-11173 SS5

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000866.5	0.51	other (other)	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000867.3	0.49	other (other)	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000255.5	0.41	PKS	pederin	Uncultured bacterium
BGC0002561.3	0.40	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0001080.5	0.37	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000286.3	0.36	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0002707.2	0.35	terpene	(+)-δ-cadinol	Coniophora puteana RWD-64-598 SS2
BGC0002363.3	0.35	ribosomal	berninamycin K, berninamycin J, berninamycin A, berninamycin B	Streptomyces sp.
BGC0000615.4	0.33	ribosomal	TP-1161	Nocardiopsis sp. TFS65-07
BGC0002220.2	0.33	terpene	Ent-kauren-16alpha-ol	Punctularia strigosozonata HHB-11173 SS5

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.71 out of 26.06

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.71 out of 26.06

Confidence: medium

ArgR

Description: Regulator of arginine biosynthesis genes
Species: Streptomyces coelicolor
Score: 18.12 out of 20.01

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.70 out of 26.06

Confidence: medium

GnfM

Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 22.80 out of 27.55

Confidence: medium

Additional weak hits (1):

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.06 out of 29.38

Confidence: weak

Detailed domain annotation

Selected features only

Show module domains

TFBS Finder

TFBS definitions

Regulator	Description
ArgR	Regulator of arginine biosynthesis genes
GnfM	Regulator of nitrogen-fixation genes
MogR	Repressor of flagellar motility genes

NZ_VOEC01000063.1 - Region 1 - cyclic-lactone-autoinducer

Download region GenBank file

Download region SVG

Location: 1 - 6,659 nt. (total: 6,659 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001291.3	0.41	ribosomal	enterocin NKR-5-3B	Enterococcus faecium
BGC0002579.2	0.39	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0002667.2	0.31	ribosomal	estericin A	Clostridium estertheticum
BGC0000624.3	0.31	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0000453.5	0.24	NRPS	valinomycin	Streptomyces tsusimaensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001291.3	0.41	ribosomal	enterocin NKR-5-3B	Enterococcus faecium
BGC0002579.2	0.39	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0002667.2	0.31	ribosomal	estericin A	Clostridium estertheticum
BGC0000624.3	0.31	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0000453.5	0.24	NRPS	valinomycin	Streptomyces tsusimaensis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.45 out of 25.88

Confidence: medium

Additional weak hits (1):

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 18.65 out of 30.11

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
PsrA	Oleic acid responsive regulator