LOCUS       NZ_VOEC01000022        22904 bp    DNA     linear   CON 11-APR-2024
DEFINITION  Enterococcus hirae strain DMW1-1 DMW1_1_contig_22, whole genome
            shotgun sequence.
ACCESSION   NZ_VOEC01000022
VERSION     NZ_VOEC01000022.1
KEYWORDS    WGS; RefSeq.
SOURCE      Enterococcus hirae
  ORGANISM  Enterococcus hirae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 171312)
  AUTHORS   Prichula,J., Frazzon,A.P.G., Seixas,A. and Gilmore,M.S.
  TITLE     Phylogenetic and comparative genomic of wild marine
            animal-associated enterococci from the southern coast of Brazil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 171312)
  AUTHORS   Prichula,J., Frazzon,A.P.G., Seixas,A. and Gilmore,M.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2019) Basic Health Sciences Department, Federal
            University of Health Sciences of Porto Alegre, 245 Sarmento Leite
            St., Porto Alegre, RS 90050-170, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 8.0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 225.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017356505.1-RS_2024_04_11
            Annotation Date                   :: 04/11/2024 14:47:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,985
            CDSs (total)                      :: 2,915
            Genes (coding)                    :: 2,801
            CDSs (with protein)               :: 2,801
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 39 of 114
            Pseudo Genes (incomplete)         :: 71 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 20 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:59:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 103920
            Orig. end                         :: 126824
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VOEC01000022.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22904
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22904
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22904
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12904](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12904
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            274..1542
                     /locus_tag="FQT05_RS10800"
                     /old_locus_tag="FQT05_10795"
     CDS             274..1542
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /locus_tag="FQT05_RS10800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10795"
                     /product="pitrilysin family protein"
                     /protein_id="WP_010737266.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.3e-29,
                     bitscore: 96.7, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYQLAEGVNLHVLQTKQYKTVRIFVRFTTRLKKEVITKRSLLSS
                     LLETNSLNYPDQTQLSAKLADLYGASFGTSVRKKGNLHWLDASINFVNGKYINDTSILN
                     QAVAFLKEVLFYPNITGEKFDPATFALEKNNLKLYLESLNEDKQTMASLALQELYFDQS
                     EAQKIPSFGTIEDLDELTAEVLADYYHQMITEDQIDIFVVGDVSPAEVQAAFSEWAFPE
                     RERLHPEIFYSQPQENIIKERQIEEPVTQAKLNLAYQTNVYYDQPDRFSLMVFNGLFGG
                     FPHSKLFMNVREKESLAYYASSSIDTFRGFLSVQTGIDGRKRNQVLHLIHEQLESLRNG
                     EVTELELTQTKAMLRNQYLLSLDAPQVAVETAYLENWLPETKLTADEWLKRMEKVTVED
                     IQKIARQIELQAIFFLDGGTTNE"
     gene            1535..2824
                     /locus_tag="FQT05_RS10805"
                     /old_locus_tag="FQT05_10800"
     CDS             1535..2824
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737267.1"
                     /locus_tag="FQT05_RS10805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10800"
                     /product="pitrilysin family protein"
                     /protein_id="WP_034867280.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 8.3e-18, bitscore:
                     58.0, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3e-18, bitscore:
                     59.6, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTEYDQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYGS
                     IDNEFIPYGSDKKIKVPDGIAHFLEHKLFEKEDGDVFQLFGQQGASANAFTSFTKTSYL
                     FSTTDQVEKNLTTLLDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILNNLY
                     PEHPLHIDIAGTVESIEAITADDLYTCYRTFYQPSNMVLFVVGKLEPEKLMELIRTNQN
                     AKDFPPAQKIERYFPDNNGDIIAKSSMRSAITRDKFVLGIKGLDVLPAEGKELLRYKTA
                     LNLLFQLLLGNTSQNYLKMYNDGLIDDSFGFEFSLDREFHFADFSGDTDQPEKAAEKVK
                     EILLHFEEDQELSEENLTLLKKKMLGQYFQTLNSLEYIANQFTQSLFGDQTLFDLPEII
                     ESIQLADVLKVGRSFIKEEAFSEFYMQPNV"
     gene            3055..3945
                     /locus_tag="FQT05_RS10810"
                     /old_locus_tag="FQT05_10805"
     CDS             3055..3945
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /locus_tag="FQT05_RS10810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10805"
                     /product="RodZ domain-containing protein"
                     /protein_id="WP_010720624.1"
                     /transl_table=11
                     /translation="MAFETIGETLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFDQ
                     LPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLSAGEVVARPEPETVSGSRKAMHQE
                     EANPSKFWTSLPVILLGLVALAIITVVGYMTWQDRKSDPIIDTTATSVSVDGAITQTTS
                     STKKERESSSSTSTTTTSTTQEEKKMAITAGEDTGSTIAVNVTDAKKPVTLEFAATNRI
                     WIGVLVDNAYVYQGTLAANETQSTQLPETATNATIRLGAASNATVKINGEEIPVNPGAN
                     NQNPKNVTLTLQYAE"
     misc_feature    3082..3100
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.1"
                     /tool="antismash"
     gene            4114..4692
                     /gene="pgsA"
                     /locus_tag="FQT05_RS10815"
                     /old_locus_tag="FQT05_10810"
     CDS             4114..4692
                     /EC_number="2.7.8.5"
                     /GO_function="GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /locus_tag="FQT05_RS10815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10810"
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="WP_135982052.1"
                     /transl_table=11
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQVTVGTTSLAVTQLVG
                     AIIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVEQGKAPGWVVA
                     IIVCRELAVTGLRLLLVEDGEVMAAAWPGKVKTATQMVAIILLFINNIPFNLINLPMDQ
                     IILYACLIFTIYSGVDYFMKNSGVFKGSM"
     gene            5008..6255
                     /locus_tag="FQT05_RS10820"
                     /old_locus_tag="FQT05_10815"
     CDS             5008..6255
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002365395.1"
                     /locus_tag="FQT05_RS10820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10815"
                     /product="competence/damage-inducible protein A"
                     /protein_id="WP_010737269.1"
                     /transl_table=11
                     /translation="MKSEIIAVGTELLLGQVVNTNATFLSEQLADLGIDVYYQTVVGDN
                     PDRLESLLQLAETRSDLIILCGGLGPTEDDLTKEVTAKHLGEELIQNTEGYKKLLAFFE
                     TTKRKMTENNLQQSQIIDGGIALPNRTGLALGTFYQTADHVYLLLPGPPSELKPMFIEQ
                     ARPLLEQNFPSEEMLISKVLRFYGIGESQLVTELKDLIETQINPTIAPYAKPNEVTLRL
                     TVKTKDKHAGNQALLVLEEKVLARVGEYFYGYGDDNSLPKVVVELLKERNQTITAAESL
                     TAGAFQSALGEISGVSQVFPGGFITYSLETKAEFLHIDDALLKQHGTVSQECAEQMAIQ
                     ARNLAKTDYAISFTGVAGPDTLEGQPAGTVWIAVATSEGEVISQKYQFTRDRSHIRNSA
                     VMQGFDLIRRQLLRKK"
     misc_feature    complement(6259..6272)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.59"
                     /tool="antismash"
     gene            6361..7401
                     /gene="recA"
                     /locus_tag="FQT05_RS10825"
                     /old_locus_tag="FQT05_10820"
     CDS             6361..7401
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /gene="recA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750141.1"
                     /locus_tag="FQT05_RS10825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10820"
                     /product="recombinase RecA"
                     /protein_id="WP_010720621.1"
                     /transl_table=11
                     /translation="MADDRKAALDAALKKIEKNYGKGSIMKLGEKIDQQVSTIPSGSLA
                     LDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQYAQ
                     KLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGDSHV
                     GLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYATIRL
                     EVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGQGISQEGELLDMAVEKD
                     IVDKSGAWYSYKEDRIGQGRENAKNYMSTHPEMMAEVSALVRAAYGIGEDVEIPEETQA
                     ELPLEE"
     gene            7970..9526
                     /gene="rny"
                     /locus_tag="FQT05_RS10830"
                     /old_locus_tag="FQT05_10825"
     CDS             7970..9526
                     /GO_function="GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /GO_process="GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rny"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /locus_tag="FQT05_RS10830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10825"
                     /product="ribonuclease Y"
                     /protein_id="WP_010720620.1"
                     /transl_table=11
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDSA
                     KKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDSLE
                     KRETSLESKEEALSSKQQLIEEREKDVEKLIEEQQRELEKIAGLSKEDAKDVIMKSTEE
                     ELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDEMKGR
                     IIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPAR
                     IEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIMGRLHFRTSYGQNVLKHSVE
                     VAKLSGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENPVVIN
                     AIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENISNSFAGVES
                     SFAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVIRETRATDYA
                     K"
     gene            10001..12904
                     /locus_tag="FQT05_RS10835"
                     /old_locus_tag="FQT05_10830"
     CDS             10001..12904
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="FQT05_RS10835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10830"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_178244026.1"
                     /sec_met_domain="DUF4135 (E-value: 3.3e-81, bitscore:
                     266.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.7e-48, bitscore:
                     157.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNYELLEYNLAEFMTSDMQEEFLQFFHFQNINEFKEQYVHSKKL
                     LKDQNEEMLNELKEWRQVDSIEKFSQQVTIKLTEQYFMKYPNLIKYKNVSNNINENLCK
                     DIHEILLRTIVYDFNLLKSQLQKLSVKSYIRNYLSNEKYVTGLFQRFPVLFNLIDKKIK
                     ETICYISEVIQHVEYDSKEINELFSIQLDQEIGVEFSSGDPHLSGKFPLVITGKKNKII
                     YKPRSNYNDLLFGECVALFNKNNFNKQLAQIKLLNRKTYSWSEFVVSDPCQSEEEVQDF
                     YYKMGAIIAILFYLNASDIHLENLIASGGSPMLIDLECLFNNLDRMEALSVNNKIHEFL
                     TNSVLNSGIVPMYNEFFKDDISALGSHENLFQRFSVPQLIVSEDDLEIKFTENSDEFKY
                     SYSNVPMYHGQNYRFLDYKQQIYQGFTETFHLFLDKKSELIDIVERYKNDITIRHLIKP
                     TATYSKIATLSYHPRFLTAPFDRLLFVYSQMARFGSTPFLTYEIEDILEGDIPYVFSKL
                     NSNTLNISKKMTFTNNSRIDFLTLWKKKIHSLSEKDLNYQLNILQKSFGDKNITLEDLF
                     IIGEKNDEIKTLESYIHSKRIVHNKQVTWLHTGYEDLTKDKDFKIRLKLQPMNNSLYNG
                     KIGVAITYYYLWKTKNDFDYKNRFLLILNDLLDHFDLSNQKNYDIGVFSGLGGYIYLFN
                     LIAPTLRTSKLIAIEQDILQYLGQKIKKDKILDIMSGTAGLLLLFCNIYKKSPNKELKK
                     LIGLCVENLLNNLIESEGKGSYWESSVEKKLILGFSHGTSGILYALAIYEELFSVTKIK
                     ETIGAVTLFENQHRKNGVWFDTRGEKWIEQNTFYCNGLVGMLTHRYFMEGESPEELLYF
                     ARLKEELNKERVDSCLCHGFLGNMWLYRHFFIHHNIKSYAFLLDDWNAYLDKRTINESC
                     LEDEFLDVGLMTGLSGVILGLLALENPNIPNILLFDL"
     gene            13029..13190
                     /locus_tag="FQT05_RS10840"
     CDS             13029..13190
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720618.1"
                     /locus_tag="FQT05_RS10840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_010720618.1"
                     /transl_table=11
                     /translation="MAVGLLMKAGNVSEELAVLNNEHSLNASLDTICGTMGSLGCGSFG
                     CGSLSSCC"
     CDS_motif       13029..13133
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MAVGLLMKAGNVSEELAVLNNEHSLNASLDTICGT"
                     /locus_tag="FQT05_RS10840_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13134..13190
                     /prepeptide="core"
                     /locus_tag="FQT05_RS10840_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.10"
                     /molecular_weight="1565.8"
                     /monoisotopic_mass="1564.6"
                     /core_sequence="MGSLGCGSFGCGSLSSCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAVGLLMKAGNVSEELAVLNNEHSLNASLDTICGT"
                     /leader_location="[13028:13133](+)"
                     /alternative_weights="1583.8"
     gene            complement(13344..14150)
                     /gene="proC"
                     /locus_tag="FQT05_RS10845"
                     /old_locus_tag="FQT05_10835"
     CDS             complement(13344..14150)
                     /EC_number="1.5.1.2"
                     /GO_function="GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /locus_tag="FQT05_RS10845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10835"
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="WP_010720617.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.1e-07, bitscore:
                     25.8, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGFIGTGNMAQAIINGLIEHETVAKEDIFVSSGHFENAQRFAE
                     ATGVTACQTNQEVAKQVDVILLAVKPKIIDQVLKDLRKYSQKCLFISIASGKSLHDLEK
                     ALNDPEAKIIRVMPNVNVSVGAGVSAICKNHHVTYEEFKEATQIFEAIGSVYPLAEGDF
                     STFIGLAGSSPAFIYMLIDAMGRAGVFNGLPKKMATEIAAKAIMGSCQKFLASDENPWE
                     LVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDREMLDKK"
     gene            14328..16901
                     /gene="mprF"
                     /locus_tag="FQT05_RS10850"
                     /old_locus_tag="FQT05_10840"
     CDS             14328..16901
                     /NRPS_PKS="Domain: LPG_synthase_C (539-822). E-value:
                     4e-55. Score: 178.8. Matches aSDomain:
                     nrpspksdomains_FQT05_RS10850_LPG_synthase_C.1"
                     /codon_start=1
                     /gene="mprF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LPG_synthase_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /locus_tag="FQT05_RS10850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10840"
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="WP_010737271.1"
                     /sec_met_domain="LPG_synthase_C (E-value: 9.6e-55,
                     bitscore: 178.8, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNKSHTAFQWLKNHSLILKMIFFGSIIVFVANQVVNIANGMSWQ
                     DIWQTMRQQSYVTLCLMVLVGLIGVLPMLLYDWVTIRVLEKQGKPKMKRHDFFLAAFIT
                     NTINNLAGFGGIVGASLRANFYGKETNRKMVLATVSKVALFMLTGLSLWSFLTFIDVFF
                     LQTTSIFRSYWIWLLGGSVIAPAIFFFAYLKRRTLFAEFYPKGLVGLLLASVGQWTGAL
                     VVFLAIGYLMDVDISLFSIYPMFIIATLIGMLTMVPGGVGTFDVLMILGMSQLAVRQDI
                     AVVWLLYYRLFYYVVPFAVGLFLFLSHTGVKVNRFLDNIPRLLFQKIAHFILVTAVYFA
                     GIMMVLLSTITNLSAISRLFQILLPFSFNFLDQTLNLLIGFLLLGLGRALAMKVKKAFL
                     PTIALLAFGIINTVTRTLSWQLILVYILILLAVWLARKEFYRKKFVYSWGAILFDLCLF
                     GFLFIVYAIAGYHSGRFWVNRLTADRFLLFPSDEVWFSGLIGLGISLLALVALYQYLAS
                     ETNELGSDLQIERFKQMLTVYQGTSASHYLRLPGYKYYYYQQNGEDQVVFGYQIKGNKC
                     FVLGDPIGNPKMIRPAITEFMQKADCLGYQIAFYKISEKYVVMLHELGFHFTKVGEVGM
                     ADLTTEEMPWVNQQLEYQRLTNEGYHFTWYEQLPEELLAAVSEVSDQWLHGAREKHFSV
                     GRFDKSYLLASGVGVVRKEQKVVGFITEQPISESQAGYDLLRVLPDEPAELSDYLLVNL
                     FVVYQEKGYLETNLGLAPLANVGETDFAFFQERIMHIVYNYGSFFYSFQSTYEEKLRYV
                     TRWEGRYFAYMKGSSFTFATLQLFILIGKGKEKSISFAEEVLTEL"
     aSDomain        15945..16793
                     /aSDomain="LPG_synthase_C"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FQT05_RS10850_LPG_synthase_C.1"
                     /evalue="4.00E-55"
                     /label="FQT05_RS10850_LPG_synthase_C.1"
                     /locus_tag="FQT05_RS10850"
                     /protein_end="822"
                     /protein_start="539"
                     /score="178.8"
                     /tool="antismash"
                     /translation="GTSASHYLRLPGYKYYYYQQNGEDQVVFGYQIKGNKCFVLGDPIG
                     NPKMIRPAITEFMQKADCLGYQIAFYKISEKYVVMLHELGFHFTKVGEVGMADLTTEEM
                     PWVNQQLEYQRLTNEGYHFTWYEQLPEELLAAVSEVSDQWLHGAREKHFSVGRFDKSYL
                     LASGVGVVRKEQKVVGFITEQPISESQAGYDLLRVLPDEPAELSDYLLVNLFVVYQEKG
                     YLETNLGLAPLANVGETDFAFFQERIMHIVYNYGSFFYSFQSTYEEKLRYVTRWEGRYF
                     AY"
     gene            17143..17991
                     /gene="ispE"
                     /locus_tag="FQT05_RS10855"
                     /old_locus_tag="FQT05_10845"
     CDS             17143..17991
                     /EC_number="2.7.1.148"
                     /GO_function="GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834412.1"
                     /locus_tag="FQT05_RS10855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10845"
                     /product="4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
                     kinase"
                     /protein_id="WP_014834412.1"
                     /transl_table=11
                     /translation="MELIEKAPAKINLGLDVLYKRPDEYHELEMVMSSVDLADHLFFEE
                     IPEDRIIVETNKAFLPVDQRNNVYQAATLLKNKYHIKKGVKIFVKKNIPVAAGLGGGST
                     DCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGNTAFVGGKGEVVQVLPSMPQ
                     CWVILVKPKMSVSTRTVFKEVDAQKIQHQNIPRLVEAIQQQDYHTMIQYMGNSLEDVTG
                     KRHPIIHQIKERMLKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCDEVYLVRT
                     L"
     misc_feature    18129..18144
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.99"
                     /tool="antismash"
     gene            18316..19266
                     /locus_tag="FQT05_RS10860"
                     /old_locus_tag="FQT05_10850"
     CDS             18316..19266
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1252: cation ABC
                     transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /locus_tag="FQT05_RS10860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10850"
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="WP_010720614.1"
                     /transl_table=11
                     /translation="MKKYMIGLTLAVGMFLLAACGGTNQKDSKKNELTIVTTFYPMYEF
                     TKEVVGNEGNVKLLIPSGTEPHDFEPSAKQQAEIADADVFVYNSPDMEFFVDSLKDSVD
                     TNKTLMIEAAKGIDRLKSAEEDHDHDHEHEEASSESHSHEYDPHIWLDPVLAIKEVKTI
                     ASELGKKYPDKKATFDKNADAYIKKLENLNQKYTDALKDAKNRTFVTQHAAFAYLANQY
                     DLHQQAIAGVTPDQEPTPSRLAELKDFVNKNKIKVIYFEENASSKVAETLSKETGVKLE
                     VLNPLESLTSEQIKAGENYISVMEENLKALKESIN"
     misc_feature    18340..18354
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.59"
                     /tool="antismash"
     gene            19284..19964
                     /locus_tag="FQT05_RS10865"
                     /old_locus_tag="FQT05_10855"
     CDS             19284..19964
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /locus_tag="FQT05_RS10865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10855"
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="WP_010737272.1"
                     /transl_table=11
                     /translation="MHYIEISDLTFYYDEEPVLEDVSYHVDAGEFVILTGENGAAKSTL
                     IKASLGLLKPSKGTVKIAPKNQEGQKLSIGYIPQQVASFNAGFPSTVLELVRSGRYPRG
                     RWFKRLSEKDHQHVKRALESVGMWEMRHRRIGELSGGQKQRISLARIFATDPDLFILDE
                     PTTGMDEESRNEFYRLLRHSAHEHGKAILMITHDHEDIKQYADRQIRLVRKEDSPWRCF
                     HMNS"
     gene            19937..20761
                     /locus_tag="FQT05_RS10870"
                     /old_locus_tag="FQT05_10860"
     CDS             19937..20761
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1245: ABC transporter
                     protein, integral membrane"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875130.1"
                     /locus_tag="FQT05_RS10870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10860"
                     /product="metal ABC transporter permease"
                     /protein_id="WP_010720612.1"
                     /transl_table=11
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSHV
                     SLAGVALGFFLNINPTLTTMFVVILAAVILEYLRTIYRTYSEISIAILMAGGLALALVL
                     MNLSGGNSATSIQSYLFGSIVTITWDQVIFLGVLFVIIGFLFFLFKRPMYVLTFDEDTA
                     HVDGLPVHRMSMLFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVVIAIS
                     IGVGFIGMLSGLTSSFYLDTPPGATITLVFIVLFLVVNLFKRVLVSIKRKNK"
     gene            20927..21745
                     /gene="purR"
                     /locus_tag="FQT05_RS10875"
                     /old_locus_tag="FQT05_10865"
     CDS             20927..21745
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /GO_process="GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="purR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /locus_tag="FQT05_RS10875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQT05_10865"
                     /product="pur operon repressor"
                     /protein_id="WP_010720611.1"
                     /transl_table=11
                     /translation="MKVRRSERLVDMTQYLLDHPHELISLTSFAERYESAKSSISEDLA
                     IIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGYVY
                     LSDLLGEPELLRQVGKIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVRRDS
                     KITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSLIEEF
                     ESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTKTKNITVVPGNYFKD"
     CDS             complement(21761..21910)
                     /gene="allorf_125681_125830"
                     /locus_tag="allorf_125681_125830"
                     /protein_id="allorf_125681_125830"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLLLVVVVFLSKISQRIPKIGETIFGFSGLFLRAGHFCHNLFQLL
                     LIGK"
     CDS_motif       complement(21830..21910)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLLLVVVVFLSKISQRIPKIGETIFGF"
                     /locus_tag="allorf_125681_125830_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21761..21829)
                     /prepeptide="core"
                     /locus_tag="allorf_125681_125830_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="2466.9"
                     /monoisotopic_mass="2465.4"
                     /core_sequence="SGLFLRAGHFCHNLFQLLLIGK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLLLVVVVFLSKISQRIPKIGETIFGF"
                     /leader_location="[21829:21910](-)"
     misc_feature    complement(22570..22585)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.56"
                     /tool="antismash"
ORIGIN
        1 tcgccacgca taataaactc tttaaattct ttaatcattt ttctcctcct ctcacttatc
       61 cttagtataa cgaagaataa aaaaatataa aaacgacatg catttatggc taaggtctgt
      121 cgttcaagta cttatatgct atactagaag gtgactctta agtgatgcaa gagagaatta
      181 aagcagtaaa aaatagtagc cacatattct tttatcctcc aagataaaat caaccatgtc
      241 ggagaacgaa ctgctaataa aggagcatgt actatgacat atcaactggc agagggtgta
      301 aacctccacg tcttgcaaac aaaacaatat aaaacggttc gtatctttgt tcgctttact
      361 acgcgtttaa aaaaagaagt catcacgaaa cgttcccttt taagtagctt gttagaaacg
      421 aacagtttaa attatcctga ccagactcag ttaagtgcaa aattggcgga tctttatggt
      481 gctagttttg gaacgtctgt gagaaaaaaa ggcaatcttc actggttgga tgctagcatc
      541 aactttgtca atggcaagta tatcaacgat accagcattt taaaccaagc tgttgctttt
      601 ttgaaagaag ttctctttta tccaaacatt acgggggaaa aatttgatcc agccactttt
      661 gctttagaaa aaaacaattt gaaactttat ttagagagct taaatgaaga caagcaaacg
      721 atggcttcac tggcgcttca agagttgtat tttgatcagt cggaggcgca gaaaatacca
      781 agttttggaa caatcgaaga tctagatgaa ctcacagctg aagtgttagc tgactattat
      841 catcagatga tcacagaaga tcagatcgat atcttcgtag tgggagatgt ctctcctgca
      901 gaagtccaag cagcttttag tgaatgggca tttccagagc gagaaagatt acacccggaa
      961 attttttata gccaaccgca agaaaatatc atcaaagagc gacagatcga agaaccagtg
     1021 actcaggcga aattaaattt ggcttatcaa accaatgtct attatgacca accggatcgt
     1081 ttttcattga tggtcttcaa tggattattt ggcggtttcc cacactctaa attatttatg
     1141 aatgttcgtg aaaaagagag cctagcttac tatgcttcca gcagcattga tacttttcgt
     1201 gggttcctaa gtgtacaaac aggaattgat ggacgtaaac gtaaccaagt attgcatctg
     1261 atccatgaac aattagaaag tctacgaaat ggggaagtca cagaacttga attgacacaa
     1321 actaaggcca tgttacgaaa ccaatatcta ttatcattag atgccccaca agtagctgtc
     1381 gagactgcct atttagagaa ttggttgcca gaaacgaaat taacagctga cgaatggtta
     1441 aaacggatgg aaaaagtaac ggtcgaagac atccaaaaaa tagctcgaca aatcgagttg
     1501 caggcaattt tctttttaga cggaggtaca acaaatgaat aaaacagaat atgatcaaat
     1561 caacgaaaca ctgtaccatg aagtattacc aaatggtttg actgtttatt tattacctaa
     1621 aaatgattac cataagacat atggtttatt tagtacaaat tacggttcga tcgataatga
     1681 atttattcca tatggttcag ataaaaagat aaaagttcca gatggtattg cccatttctt
     1741 ggaacataaa ttgtttgaaa aagaggatgg cgatgtcttt caattatttg gacaacaagg
     1801 ggcctcagct aacgcgttta ccagttttac caaaacaagt tatttatttt caacgacaga
     1861 tcaagttgaa aaaaatttga cgactttact tgattttgtc caagcacctt attttacgga
     1921 agaaacagtt aataaagaaa aagggatcat tgggcaagaa atacaaatgt atgaagatga
     1981 tccaaattgg cggatgtttt ttggcatttt gaataattta taccctgaac atcctttgca
     2041 tatcgatata gctggcacag ttgaaagtat tgaagcaatc actgctgatg atttatacac
     2101 gtgctatcgg acattttatc agccaagtaa tatggtcttg ttcgtagtag gaaaattaga
     2161 gccggaaaag ttgatggaat tgattcgaac caatcaaaat gctaaggatt ttccaccagc
     2221 tcaaaaaatc gaacgttatt tccctgacaa taatggtgat attattgcga aaagctcaat
     2281 gcgctcagca atcactagag ataagtttgt cttgggaatc aaagggctag atgttttacc
     2341 agcagaaggg aaggaattat tgagatacaa gactgctctc aatcttttat tccaattgtt
     2401 attagggaat acttctcaaa attatttgaa aatgtacaat gatggtttaa ttgatgacag
     2461 cttcggtttt gaatttagtt tagatcgaga atttcatttt gctgacttta gcggagacac
     2521 ggatcagcca gaaaaagcag ctgaaaaagt gaaagaaatt cttctgcatt ttgaagagga
     2581 tcaagaactg tctgaagaaa atctaacatt gttgaagaaa aagatgttag gacaatattt
     2641 ccaaacatta aattcactgg aatacattgc aaaccaattc acgcaaagcc tatttgggga
     2701 tcaaacatta tttgatttac cagaaattat tgaatccatt caattagcag atgtattaaa
     2761 agtaggtcgt tcttttatca aagaagaagc gttcagtgag ttttatatgc agccaaatgt
     2821 ctgatataga agtagagatg acgaatggga aagtagttaa actcttaaat ttcgttatag
     2881 agtgcattca atgttaccct aagataactt cgtttatggt attcttaaga agataaagaa
     2941 taaaaaatgg gcgttggtgt atggcgtgtt acattcttaa cgaaaaggaa caattagacg
     3001 actagcgttt atacaattgc tggttagaat aaaaagactg gagaagatga acgagtggct
     3061 tttgaaacca tcggagaaac attaaggcaa gctcgcctaa ataagaaaat atctttagat
     3121 gaattacagc agattacgaa aattcaaaaa cgttatctag aagcaatcga taatgatgat
     3181 tttgatcaac tacctggaaa attttatgtt cgggcattta ttcgtcaata tgcagaagct
     3241 gtcggtgaag atggcgatca tttagttgat gtatttgatg ggaaaagcaa attatcagct
     3301 ggagaagttg tcgcacgtcc tgaaccagaa acagtgagtg gttcgagaaa agctatgcat
     3361 caggaagaag ccaatccaag taagttttgg acaagtctac cggttatttt acttggttta
     3421 gtcgctttag caattattac tgttgtgggt tatatgactt ggcaggatcg aaaatctgac
     3481 ccgattattg atacaacggc aacttcagtt tcggttgacg gtgcaattac acaaacgaca
     3541 tctagcacta agaaagagcg tgaatcctct tcttcaacaa gtacgacaac cacttcaaca
     3601 acacaagaag agaaaaagat ggcgattacg gctggtgaag acacaggtag tacgatcgca
     3661 gtgaatgtta cggatgcgaa aaaacctgtt acacttgaat ttgcagcgac taaccgaatt
     3721 tggatcggtg tattagtgga taatgcctat gtttatcaag ggacattagc agcaaatgaa
     3781 acacaaagca cgcaattacc ggaaacggca accaatgcaa cgattcgatt aggagctgca
     3841 agtaatgcaa cggttaagat aaacggggaa gaaatccctg ttaatccagg agcgaataat
     3901 caaaatccta aaaatgtcac attgacacta cagtatgcag agtaaatcgc ttataagtag
     3961 aatgatgtga aaaaagaaaa caagataagt acctgggaag gcagattcat cttaggtgct
     4021 tatctttttt cacgactgct gataaaaact gatcattatc ggtggaaagt ttagaacgag
     4081 tcacgtagaa tagggaagaa aggagtcgat agtgtgaatt taccaaataa attaactgta
     4141 cttagaattt gtatgatccc gatttttatt ttagttgtcg gattaccctt agattgggga
     4201 caagtaaccg taggaacaac atcacttgct gtgacgcaat tagtaggagc gattattttt
     4261 gctttagcaa gtattaccga ttggctcgat ggaaaaattg ctcgtgccag aggattagtc
     4321 accaattttg gaaagtttgc tgatccatta gcagataaaa tgttagtgat gaccgctttt
     4381 atcatgttgg tggagcaagg taaggcacca ggatgggtag ttgcgattat cgtttgtcga
     4441 gaactagctg ttaccggtct gcgactattg ttagtcgaag atggggaagt catggcagca
     4501 gcgtggccag gaaaagtaaa aacggctacg caaatggtgg ctattatttt gttattcatc
     4561 aataatattc catttaatct gatcaattta ccgatggatc aaatcatact gtatgcttgt
     4621 ttgatcttca cgatttattc aggtgttgat tattttatga aaaatagtgg tgtgttcaaa
     4681 ggttcgatgt aagattcctt acaaagatgt accatttcga taattcgtct taccccaaaa
     4741 taacatttta tattttgggg taagacgaat ttatttatgc tgattcacgt ttcaatcatt
     4801 tatttgatcg ccatttttct aaactagcta gatgcctagc tatcttatga tgaagatgaa
     4861 aatgatgaaa ctctttatca gaaaatgagc aaatgataaa tgaaacgttt agcaaatggc
     4921 gtatactatt agtagataaa aagagattga gaagagacca aaacaggcca acgagaattc
     4981 gtctgttgta atgaaggaag cgaaaaaatg aaatcagaaa tcatagcagt agggacagaa
     5041 cttttactag gacaagtagt caacacgaat gccacgtttt tatccgaaca gttagcagac
     5101 ctcgggattg atgtgtatta tcaaacggtg gttggtgata atcccgaccg cttagaatca
     5161 ttactccaat tagcagaaac cagaagtgac ttgatcattt tatgtggagg gttgggaccg
     5221 acagaagacg acctgacgaa agaagttact gcgaaacatc taggggaaga attgatccaa
     5281 aacaccgaag gctataaaaa attgttagca ttttttgaaa cgaccaagcg taaaatgact
     5341 gaaaataatt tacaacaatc acaaatcatc gatgggggga ttgctttacc taatcgcaca
     5401 ggcttagcat taggtacgtt ctatcaaaca gcagaccatg tctatctctt gttacctgga
     5461 ccaccgagcg aattaaagcc aatgttcatt gaacaagctc gcccattatt ggagcaaaac
     5521 tttccatctg aagaaatgct gatctcaaaa gttttacgtt tttacggtat cggggaatcc
     5581 caactagtca cagaattaaa agacttgatt gaaacacaga tcaacccaac gattgcccct
     5641 tacgcaaaac ctaacgaagt cactttacga ttaactgtga agaccaaaga caaacatgca
     5701 ggaaaccaag ccttacttgt tttggaagaa aaagtattgg cgagagtagg tgagtacttc
     5761 tatggatatg gtgatgataa ttcattgcct aaagtggtcg tagaattatt aaaggaaaga
     5821 aaccaaacaa taactgcagc agaaagtttg actgctggag cctttcaatc agctttggga
     5881 gagatctctg gtgtttctca agtcttccca ggaggcttca ttacctattc tttagaaact
     5941 aaagcagaat ttttacacat cgatgatgca ctattgaagc agcatggaac cgtcagccaa
     6001 gaatgtgcag aacaaatggc tatccaagca cgtaatttag caaaaacaga ttatgcgatt
     6061 tcgtttactg gagtggctgg accagatacc ttagaaggac agccagctgg aacagtttgg
     6121 atcgcggttg caacaagcga aggggaggtc atttcgcaga aataccaatt taccagagac
     6181 cgttctcata taaggaatag cgcagtaatg caaggatttg atctcattag aagacaacta
     6241 ttaagaaaaa aataaatgcg aatatttgtt cggttttttc ttgctttttg tcattaaaaa
     6301 cgatatgatt agtacaatga aatgtcgcac tgatttgtga atataaggag gattatcgta
     6361 ttggcagatg atcgtaaagc agccttagat gctgcgttga aaaaaattga aaagaactat
     6421 gggaaaggct cgatcatgaa acttggcgaa aaaatcgacc aacaagtttc gactatccca
     6481 agtggttctc ttgcattaga tgttgcttta ggtgttggtg gttacccacg aggacgtatc
     6541 attgaagtat atggtcctga aagttcaggt aagacaaccg ttgccttgca tgcaatcgct
     6601 gaagtacaaa aaaatggcgg aacagccgct tttatcgatg ctgagcatgc cttagaccca
     6661 caatatgctc aaaaattagg ggtaaacatt gacgaattac ttctttcaca accagatact
     6721 ggggaacaag gactagaaat cgctgatgcg cttgtatcaa gtggtgcagt agatatcgta
     6781 gtagtcgatt cggttgcagc tttagttcca cgtgctgaaa tcgatggaga aatgggtgac
     6841 tctcacgtag ggttacaagc tcgattaatg tcacaagcat tgcgtaaact atctgggtcg
     6901 atcaataaaa caaaaacgat cgctattttc attaaccaaa ttcgtgaaaa agttggagtg
     6961 atgttcggta atcctgaaat cacacctggg ggacgtgcat taaaattcta tgcaacgatt
     7021 cgtttagaag tgcgccgtgc ggaacaattg aaacaaggaa cagacattgt tgggaaccgt
     7081 acgaagatca aagtagttaa aaataaagta gcgccaccat tcaaaattgc tgaagtcgat
     7141 gtgatgtatg ggcaaggaat ttctcaagaa ggagaattgc ttgatatggc ggttgaaaaa
     7201 gatatcgttg ataaaagtgg tgcttggtat tcttacaaag aagatcgtat tggacaaggt
     7261 cgtgagaatg caaaaaatta catgtccact catcccgaaa tgatggcaga agtttctgct
     7321 ttagtccggg cggcttatgg gatcggtgaa gatgtagaaa tacccgaaga aacgcaagca
     7381 gaacttcctt tagaggaata agatgaagta agaatagaaa taatcgaata actattcaaa
     7441 ggatgtttga gcatcgagag aactcgcgtc gttcagagaa agtgttttcc tttgatatgt
     7501 tgtcgattga atctaataag ccgaaatttt ttaaaatttc ggcttatttt ttgtctttta
     7561 agtagtcatt tgactatact ttctcctaaa acataatggg aaatgggaat gtttatgcag
     7621 tgactgacta catcggcaga aagggactat tctacttaaa tgaaaggata gtttgttact
     7681 taaaagtcat tttttgttct taattttcat taatgcaaaa ttatttgttc ttaatatgtt
     7741 ttggttatta tttaatatta tcttttattc ataaaatgac ctttaaatga aaatagagaa
     7801 agccgtttct tatgtattta aagttgacac tacggggtac aaacattaga ataaacttgt
     7861 gcatgttttt gtacacctat gcataaagca tattaacaag tttagagtac tttatcataa
     7921 aagttatata gatgataaaa atgaaaaaga tagtatggag gtggatttta tggtattcaa
     7981 tattctcctc gctatcatcg gtttaattgt cggtcttggt ttagggttta tggttgcaaa
     8041 gtcacgtcat gaaaaagaaa ttgcaggtgc tcaatcatca gcagctggaa ttattgatag
     8101 tgcaaagaaa gaagcagaaa ctctaaaaaa agaagcattg ttagaagcta aggaggaaaa
     8161 ccagaaatat cgttctgaag tggagagtga gttgagagaa agcaagttag aattaaaatc
     8221 tcaagaaaat cgtttaattc agcgtgaaca aacgttgaat cgtaaagatg actcattgga
     8281 aaaacgtgag acctcacttg aaagcaaaga agaagcactt agttcaaaac agcaattgat
     8341 tgaagagcga gaaaaagacg ttgaaaagtt gattgaagaa caacaaagag aattagaaaa
     8401 aattgctggt ttatctaaag aagatgcaaa agatgtcatc atgaaatcaa ctgaagaaga
     8461 attgaatcat gaattgacgt taatggtcaa agaatcggaa caacgtgcaa aagaagaagc
     8521 agatcgtaaa gccaaaaatc ttttatcgtt agcgattcag cgctgtgcgg cagaccaagt
     8581 atctgaaaca actgtatccg tagtaacttt accaaatgat gaaatgaaag gacgcatcat
     8641 tggtcgagaa ggacgaaata tccgtacact agaaacattg actggaattg acttgatcat
     8701 tgatgataca ccagaagcag tggtcctttc aggttttgat ccaattcgta gagaaatcgc
     8761 tcggatgact ttagaaaaac tgatccaaga tggacggatc catcctgcac gaatcgaaga
     8821 aatggtcgaa aaatcgcgta aagaaatgga tgaacgaatc cgtgagtacg gggaagaagc
     8881 ggcgtttgaa gttggtgcgc atacccttca tccagatttg atcaaaatca tgggtcgtct
     8941 tcattttaga actagctatg gacaaaatgt tttgaaacat tcagtagagg ttgctaaatt
     9001 gtcaggtata ctagccgctg agttaggcga agatatccaa ttagctaaac gagctggttt
     9061 gcttcatgat atcgggaaag cattagatca tgaaatcgaa ggttctcacg tagagatcgg
     9121 tgcagagtta gctgctaaat acaaagaaaa tcctgtagtg atcaatgcga ttgcatctca
     9181 tcatggagat gttgaagcaa cgtcagttat ttctgtcttg gtagctgctg cagatgcctt
     9241 atccgctgca cgaccaggag ctagaagtga atccttggaa aattatatcc gtcgcttaag
     9301 aagcttagaa aacatttcaa atagctttgc cggagtagaa tctagttttg ctgttcaagc
     9361 tggacgagaa gttcgggtta tggtaaaacc agaagagatc tctgatttag atgcagttcg
     9421 tttagtacga gatattcgta aacgaattga agaagaatta gattatccag ggcatatcaa
     9481 agtcatcgtt attcgtgaaa cgcgtgcgac agactacgct aagtaaaaaa taaaagaacg
     9541 ttacgattag ttaggataat cgtagcgtct tttttgtttt aaaccactat ttaatcaagc
     9601 ttgatcgctt taacattatt ttgataagag gttgagcagc tataaacttg gtgtgttaac
     9661 tttgagttct aaattagctt cttaataaga agtaggcata atctaactag agacgattat
     9721 tctatcatta aagtagatca aaattattct taatgactac tagaaaatca aactaggatg
     9781 aagaatagtt aggaaataaa atttgttgca ttagtgtaca tttttttaac gagagataaa
     9841 agttgtataa actagtaata tattgatcta tgagtttgaa atcaatttta tgtacaattt
     9901 tttactagga tttattgggt agaaagatat agtttttgtt cttgaaaaca caagtaattg
     9961 attctatatg atctaaatat agatgaggtg gggtaagcag atggataatt atgagttgtt
    10021 ggaatacaat ttagcagaat ttatgacttc agatatgcaa gaggaatttt tacaattttt
    10081 tcattttcag aatattaatg aatttaagga acagtatgtt cattcaaaaa aactgctaaa
    10141 agatcagaac gaagagatgt tgaatgaact aaaagaatgg agacaagttg attcaattga
    10201 aaaattctcg caacaagtaa caataaagct aactgagcaa tattttatga agtacccaaa
    10261 tctaataaaa tacaaaaatg ttagcaataa cattaatgaa aacctttgca aagatattca
    10321 tgagattctt ttgcgaacga ttgtttatga ctttaatcta ttaaagtcac agttacaaaa
    10381 actctctgtg aaaagttata ttagaaatta tttatctaat gagaaatacg tcacaggttt
    10441 gtttcaaaga tttcctgttt tattcaattt aatagataaa aaaatcaaag aaacaatttg
    10501 ttacatttct gaagttatcc aacatgtaga gtatgattca aaggaaatta acgaattgtt
    10561 tagtattcaa cttgatcaag aaataggagt tgaattttct tcgggtgatc cgcatctgtc
    10621 aggaaaattt ccactcgtga taacaggtaa aaagaataaa attatttata aaccacgaag
    10681 taattacaat gatttattat ttggagaatg cgttgcttta tttaataaaa ataattttaa
    10741 caaacaacta gcacaaataa aattattgaa tcgtaaaacg tattcttggt cagaatttgt
    10801 tgtaagtgat ccttgtcaat cagaagaaga agttcaagat ttctattata aaatgggggc
    10861 aattattgca attcttttct atttaaatgc ttcggatatt catcttgaaa atctaattgc
    10921 aagtggtggt tcacccatgc tcattgattt agaatgcttg tttaacaatt tagatcgtat
    10981 ggaagcatta tctgtaaata ataagataca tgaatttttg actaattctg ttcttaattc
    11041 tggaattgta cctatgtaca acgaattttt taaagatgat atttcggctt taggaagtca
    11101 tgaaaactta ttccaacgtt tttcagtacc acaattgatt gtttcagaag atgatttaga
    11161 aattaaattc actgaaaatt ctgatgaatt taaatattca tattctaatg ttccgatgta
    11221 tcatggacaa aattatcgtt ttttagacta taagcaacag atctatcaag gatttacaga
    11281 aacatttcac ctatttttgg ataaaaaatc agagctgatt gatattgttg agcgctataa
    11341 aaatgatatt actatccgac atttaataaa accaacagca acttacagta aaatagcgac
    11401 tttaagttat catcctaggt tcttgacagc accgtttgat cgcttgttat ttgtctattc
    11461 tcaaatggca agatttggtt ctacaccatt tcttacctat gaaattgagg acatactaga
    11521 gggggatatc ccttatgttt tttcaaaact taactcaaat acacttaaca tttcaaaaaa
    11581 aatgacattt acgaataaca gtcgtataga tttcttaaca ctatggaaaa aaaagatcca
    11641 ttctcttagt gagaaagatt taaactacca attaaatatt ttgcaaaaaa gctttggaga
    11701 taaaaatatt acgttagaag atctttttat aattggagaa aaaaatgatg agatcaagac
    11761 tttagaatct tacatccata gtaaaaggat agtacacaat aagcaggtga cgtggcttca
    11821 taccggttat gaagatttaa caaaagacaa agattttaaa attcgtttaa aactgcagcc
    11881 aatgaataat agtttgtata atgggaaaat tggtgtagca atcacttact attatttatg
    11941 gaaaacaaaa aatgattttg attacaaaaa cagatttcta ttaatattga atgatttact
    12001 tgatcatttt gatttatcta atcaaaaaaa ttatgatata ggggtttttt ctggattagg
    12061 tggttatatc tatttattta atttgattgc tccaaccttg cgaacatcaa aactgatcgc
    12121 aattgagcaa gatatccttc aatatctggg acaaaaaata aaaaaagaca aaattctgga
    12181 tattatgagt ggtacggcgg ggttattact acttttttgt aatatttata aaaagagccc
    12241 taataaagaa ttaaaaaaat taattggact ttgtgtggag aatttattaa ataatttaat
    12301 agaatcagag ggaaaaggaa gttattggga atcctctgta gaaaagaaac ttattttagg
    12361 tttttctcac ggaacatcag gtattcttta tgctttagcg atttatgaag agttattttc
    12421 ggtaaccaaa ataaaagaaa cgattggcgc agttacctta tttgaaaacc aacatcgtaa
    12481 aaacggtgtg tggtttgata caagaggaga aaaatggatt gagcaaaata ctttttattg
    12541 taatggtctt gtaggaatgc ttactcatcg atattttatg gaaggagaaa gcccagagga
    12601 gctattatat tttgctcgat taaaagaaga attaaacaaa gaacgtgtag atagttgctt
    12661 atgtcatggc tttttaggaa atatgtggct ttaccgtcat ttcttcattc atcataatat
    12721 aaagtcatat gcgttcttac tcgatgattg gaatgcatac ttagacaaac gaacaattaa
    12781 tgaaagttgt ttagaagacg agtttctaga tgttggtttg atgaccggtc tttccggggt
    12841 gattttggga ttgttagcgt tggagaaccc taacatacca aacatacttt tattcgattt
    12901 atagataaat ccttcaaccg aaaatacgaa tgaagagata ggatctgatt gaataataga
    12961 ttgataagtg taacaaacag ttgatgacaa taaaaaatga ttgatcaact tgaaaggagg
    13021 tgaagaaaat ggcagtagga ctattaatga aagcaggcaa tgtttctgaa gaattagcag
    13081 tattaaacaa cgaacatagt ttgaatgctt cgctagatac catctgcgga acaatgggta
    13141 gccttggttg tggtagtttt ggttgtggct ctttatctag ctgttgctaa aatatatacg
    13201 gatgaaaggt ttcagaggtt ttattgtgaa tattgaaaaa taataattca gaatgaagag
    13261 tctgaatctg ggacattaat cagaaaaaat ctgattaatg tcctactttt tttagtaaaa
    13321 agattccttc agactcattc gttttatttc ttatccagca tttctcgatc tttttcgatc
    13381 gttgtattga tccctttgat aatagcagga atgaagccag cttcttctaa agccacaaca
    13441 cctgcaacgg ttgttccgcc aggggaagaa acctggtcaa ctagctccca agggttttca
    13501 tcacttgcta ggaatttttg acaagatccc ataatagctt tggcagcgat ctcggttgcc
    13561 atttttttag gtaagccatt aaagacaccc gcacgaccca tggcatcgat caacatataa
    13621 ataaatgctg gtgaactacc ggctaaccca ataaacgtac tgaaatcacc ttctgccagt
    13681 ggatagacac tgccgattgc ttcaaagatt tgcgttgctt ctttgaattc ctcatatgtg
    13741 acatgatgat ttttacagat agcagagaca cctgcaccca cactaacgtt tacgtttggc
    13801 atgacacgaa tgattttcgc ttcggggtca tttagggctt tttccagatc atgtaatgat
    13861 tttcctgaag caattgaaat aaagagacat ttctgactat attttcttaa atccttcagt
    13921 acttggtcaa tgattttagg tttgactgcc agtaaaatga catctacttg ttttgcgact
    13981 tcttgatttg tttgacaggc ggttacacca gttgcttctg caaaacgttg tgcattttcg
    14041 aaatgaccac ttgagacaaa aatatcttct ttagccactg tttcgtgttc aatcaagccg
    14101 ttaatgattg cttgcgccat attacctgtt ccaatgaatc caattttcat gttatcctct
    14161 ccttttgttt tagcatagct ttcttttcaa tgaagggcaa gcaaagaata aagcgtgtgg
    14221 ataatagata cataaacagg tgaaactagt gcataagtgg taaaaataag gtaaataagc
    14281 taacattgat ttataaattg aaagttttca agtaaggatg gtaaagtgtg aaaaataaaa
    14341 gtcatacggc atttcagtgg ttgaaaaatc atagcttgat tttaaaaatg attttttttg
    14401 gatctattat agttttcgtt gccaatcaag tcgtaaatat tgcaaatgga atgagttggc
    14461 aagatatttg gcaaactatg cgacaacaaa gttatgttac gctgtgttta atggttttag
    14521 tggggttgat cggtgttttg ccaatgttgt tgtatgactg ggtgacgatt cgcgtgttgg
    14581 aaaaacaagg gaaacctaaa atgaagcgtc acgatttttt cttagctgct tttattacga
    14641 atacaattaa taacttagcg ggctttggag gaattgttgg agctagtctt agagcaaatt
    14701 tttatggaaa agaaacaaat cggaaaatgg tacttgctac cgtttctaaa gttgcattat
    14761 ttatgttgac tggtttatca ttatggtcat ttctaacgtt cattgatgtt ttttttctac
    14821 aaactactag tatttttaga agttattgga tttggttact tggcggtagt gtgatagcac
    14881 cggctatttt tttctttgct tatttaaaaa gaagaacatt atttgcggaa ttctatccta
    14941 agggtctagt cgggttactg ttagcttctg tggggcaatg gactggagca ttggtcgttt
    15001 ttttagcgat tggttatttg atggatgtag atatttcctt attttcgatt tatccaatgt
    15061 ttattatcgc tacgttaatc ggtatgttga caatggttcc tgggggtgtc gggacatttg
    15121 atgtgttgat gatcttaggt atgagtcagt tagctgttcg acaagatatt gcagtggttt
    15181 ggttacttta ttaccgtttg ttttattatg tggttccttt tgcggttggc ttatttttat
    15241 ttctgtcaca tactggagta aaagtgaatc gttttttaga caatatacca cgactgctct
    15301 ttcaaaaaat cgcgcatttt attttggtca cagccgttta ttttgcaggg atcatgatgg
    15361 tgttactatc tacgattacg aatctttctg cgatcagtcg attgtttcag attttattac
    15421 ctttctcgtt taatttttta gaccaaacgt tgaatctatt gattggattc ttattgcttg
    15481 ggttgggaag agcgttagca atgaaagtga agaaggcttt tttaccaact attgctttat
    15541 tagcttttgg aatcattaac acagttactc gaacattatc ttggcaattg attttagtgt
    15601 atatcttgat tcttctggct gtctggctag ctcggaaaga attttaccgt aaaaaatttg
    15661 tttattcatg gggtgccatt ctttttgatc tatgtttgtt tgggtttcta tttatcgtct
    15721 atgcaattgc agggtatcat agtggacgtt tttgggtaaa tcgattgaca gctgatcgct
    15781 ttctcctgtt cccatccgat gaagtttggt tttcaggctt gattggtcta gggatctcgc
    15841 tgttggcatt agtagcattg tatcagtacc ttgcttctga aacgaatgag ttagggtcag
    15901 atttacaaat cgaaagattc aaacagatgt tgaccgtcta tcaggggaca tctgctagtc
    15961 attatcttcg tttaccagga tataaatatt attactatca acaaaatgga gaggatcaag
    16021 tcgtctttgg ttaccagatc aaaggaaata aatgctttgt tttgggagac ccgattggca
    16081 atcctaaaat gattcgtcct gctattacag aatttatgca aaaagctgat tgcttagggt
    16141 atcaaattgc tttttacaag atctcagaaa aatatgtggt aatgttgcat gaattaggtt
    16201 ttcattttac aaaagtcggc gaagtaggaa tggcagattt gactacagaa gaaatgcctt
    16261 gggtcaatca acagctagag taccagcgtc taactaatga aggctatcat ttcacttggt
    16321 acgaacaatt acctgaggaa ttattagctg cggtgagcga ggtttcggat cagtggttac
    16381 atggtgcgag agaaaagcat ttttctgttg ggcgttttga caaatcttat ctgttagcca
    16441 gcggtgttgg agtggtacgc aaagaacaaa aagtggtcgg atttattaca gagcaaccaa
    16501 tatctgaaag ccaagcaggc tatgatctat tacgtgtatt gccagatgaa cctgctgaac
    16561 tatccgatta tttattagtc aatctatttg ttgtctacca agaaaagggc tatcttgaga
    16621 caaatcttgg tttagctccg ttagcaaatg taggggaaac agactttgca ttctttcaag
    16681 agcgcatcat gcatattgtt tataattatg gtagtttttt ttactccttt caatcgacct
    16741 atgaagaaaa actgcgctat gtcactcgtt gggaaggtcg ctattttgct tacatgaagg
    16801 gaagcagttt tacatttgcc acattacagt tgtttatact aattgggaag ggaaaagaaa
    16861 aaagtatcag ttttgcagaa gaagtattaa cggaattgta aattgcgtaa atagaggaat
    16921 aactggtgac gtattttagc tacccatagt ttaaaacgtg aaaaagcgat tgacggtagc
    16981 tagagacaat gaatgtggtc gaaggatggt ttgttttatc tgtagacaga aaaggtctga
    17041 gaaaactgct aagatcgtaa acacgtcact cgtatgagct atacttttat ttttctctgt
    17101 gatagaatac ttgcgactta gactttttga atgggtgaga ggatggaact gatagaaaaa
    17161 gcaccagcta agatcaattt gggattagat gtcttgtaca agcgtcccga tgagtatcac
    17221 gagctggaaa tggtaatgtc gagtgtagat ttagcagatc acttattctt tgaagagata
    17281 cctgaggatc gaatcatcgt agaaacgaat aaggcatttt tgccagtaga tcaacgaaat
    17341 aacgtttatc aagcagcaac attgcttaag aataagtatc atatcaaaaa aggcgtaaaa
    17401 atatttgtga aaaaaaatat tccagttgca gctggactgg gtgggggcag cacagattgt
    17461 gcagctgcac tgagagggat caatcaacta tggaatctcg gttgttctct ggaagaatta
    17521 gctgagattg gtttggaagt tggtacggat gtgccttatt gtgtttatgg taatactgcg
    17581 tttgttggcg gcaaaggaga agtggtccaa gttctccctt caatgcctca gtgttgggta
    17641 atcttggtga aacctaaaat gagtgtttcg actaggaccg tcttcaaaga agtagatgcg
    17701 caaaaaatcc agcatcagaa cattcctaga ctagtggagg caatccagca acaagattac
    17761 catacgatga ttcaatacat gggaaatagt ttagaagatg ttaccggcaa acgtcatcca
    17821 attatccatc aaatcaaaga acgcatgtta aagtatgggg cagatgccgc tttgatgagc
    17881 ggaagcggac cgacagtctt tgccttatgt caacattatt caagagcaca aagagtctat
    17941 aacgggctga aaggtttctg tgatgaagta tatttagtac gcacgttgta aaataggcca
    18001 gaactagttg ttgctaagag atgaagaata aaaaatctca aaacagaaga agctgttttg
    18061 agattttttt gagttggttg cagcttagtt actctaaacg ttatttattc tatttagaaa
    18121 ttggaaaaaa tggtctagat aacttgttgg gctctcagta acatgaataa actatcattc
    18181 attttacggt ttacattgaa tttattcgta taaatcagaa attgaaggat ttctattgac
    18241 tctatttttt tattctgata cattaagttc cgttgataaa tcgtaatttt acgatttgtt
    18301 cgaaaggaga gtcttatgaa aaaatatatg attggtttaa cactagctgt agggatgttt
    18361 ttattagcgg cttgtggtgg tacgaaccaa aaggattcaa agaaaaatga gttaacgatt
    18421 gttacgacct tttatccgat gtatgaattt acgaaagaag tagttggaaa tgaaggaaac
    18481 gtcaagttgt tgatcccatc tgggactgaa ccgcatgatt ttgaacctag tgcaaaacaa
    18541 caagcagaaa tcgctgatgc ggatgtgttt gtttataata gtccagatat ggaatttttt
    18601 gttgattcat tgaaagattc tgtcgatacg aataaaacat tgatgattga agcagctaaa
    18661 ggaattgatc gtctgaaatc agcagaagaa gaccatgacc atgatcatga acatgaagaa
    18721 gcttcttctg aaagtcattc gcatgagtat gatccacata tttggttaga tcctgtgtta
    18781 gcaatcaaag aggtcaaaac aattgcttca gagcttggga aaaagtatcc tgataaaaag
    18841 gcaacttttg ataaaaatgc ggatgcttat atcaaaaaat tagaaaatct gaaccaaaaa
    18901 tatacggatg cactcaaaga tgccaaaaac cgcacgtttg tgacgcaaca tgccgcattt
    18961 gcgtatttag cgaatcagta tgatttacac caacaagcga ttgcaggggt aacgcctgat
    19021 caagaaccca caccaagccg cttagctgaa ctaaaagatt ttgtgaacaa aaataagatt
    19081 aaagtgattt attttgaaga aaatgcgtca tccaaagtgg cagaaacatt gtcgaaagaa
    19141 acgggtgtta aattagaagt attgaatcca ttagagagtt tgacaagtga acaaatcaaa
    19201 gcgggtgaaa attatatttc ggtaatggaa gagaacttaa aagcgttaaa agaaagtatt
    19261 aattaagaac ggaggcattt cgcgtgcatt atatcgaaat atccgatttg actttttatt
    19321 atgatgaaga acctgtatta gaagatgtgt cttatcacgt tgatgcagga gagttcgtta
    19381 ttctaacagg agaaaacggt gcagcaaaat caacattgat caaagcttcc ttaggcttgt
    19441 taaaaccttc taagggaaca gtgaaaatcg ccccaaaaaa tcaagaagga caaaaattaa
    19501 gtattggtta cattccccaa caagtggcat cttttaatgc tggctttcca agtacagtct
    19561 tagaattggt tcgttccggt cgctatccga gaggacgttg gttcaaacga ctttctgaaa
    19621 aagatcatca gcacgtcaaa cgagctttag aatctgttgg aatgtgggag atgcgtcatc
    19681 gacggatcgg agaattatcc ggtggacaga aacaacggat tagcttagcc cgtatttttg
    19741 cgactgaccc agatttattt atattggatg aaccgacaac ggggatggat gaagaatctc
    19801 gtaatgaatt ttatcgacta ttgcgtcata gtgcccatga acatggtaag gcaattttga
    19861 tgattactca tgatcatgag gatatcaagc aatatgcaga tcgacaaatt cgtttggtaa
    19921 gaaaggagga ttctccatgg cgttgctttc atatgaattc atgagacgag cttttttagc
    19981 agccattttt attgcgggga ttgctccaat gttaggtgtc tttttagtga tccgaagaca
    20041 atcattgatg gcagatacac tgtcacacgt ttcactggca ggggtggcat tgggtttctt
    20101 tttgaatatc aatccaacgt tgactacgat gttcgtagta atattagctg cggtgatttt
    20161 agaatattta cgtacgattt atcgtactta ctcagaaatt tcaattgcga tcttaatggc
    20221 tggcggactg gcgctggcat tagttttgat gaatcttagt ggtggaaact cagccacaag
    20281 tatccaatcg tacctctttg gctcgattgt gacgattact tgggatcaag ttatcttttt
    20341 gggtgtatta tttgttatta ttggtttctt attctttttg ttcaagcgac caatgtacgt
    20401 gctgactttt gatgaagata ccgcccatgt tgatggtctg cctgttcacc gtatgtcaat
    20461 gctgttcaac gtgatcacgg gtgttgcgat tgctgtcatg atcccaattg ccggggcatt
    20521 attgatttca gcaattatgg tcctgcctgc agcgatcggt atgcgcttag gcaaaagttt
    20581 caatgtggtg attgccatta gtatcggggt tggctttatc ggcatgttat caggactaac
    20641 aagttccttt tatctagata cgccaccggg tgcgacgatc acgctagtct ttatcgtgtt
    20701 gtttcttgtg gtcaatttgt tcaagcgggt gcttgtttcc attaagcgaa aaaataaata
    20761 aaaaatcaaa aagaaaagcg atgaaaacga aaaattttca ttgctttttc ttatatttag
    20821 ataaataccg aactatttaa cttattttct tacaaaatgc tcgaattttt aaatgaaaac
    20881 ttatataatg taaaacgata taatttctta aaaggagctg aaatatgtga aagtacgtcg
    20941 cagtgaacgt cttgttgata tgactcagta tttattagat catcctcacg aattaatttc
    21001 attgacaagt tttgccgaac gttatgaatc tgctaaatct tcgatcagtg aagacttggc
    21061 aattatcaaa aaaacattta aggaacgagg gtatggtact ctagaaacaa ttccaggtgc
    21121 cgctggtggg gttttattta taccagagat ttcttacgaa gaagccaaaa aatacattga
    21181 gtctttagct gaacgattgt ctgaacaaga tcgtttgttg cctggaggtt atgtttatct
    21241 atccgattta ctaggtgagc ccgaattatt gcgccaagtt ggaaaaatca ttgcttctaa
    21301 gtatttaggt gaaaaaatcg atgcagtgat gacagttgct acgaaaggtg taccgatcgc
    21361 gcaagctgtg tcctattatt taaatgcacc gtttgttatc gtacgccgtg attcaaagat
    21421 cactgaagga tcgacagtta gtgtgaatta tgtttctggt tcttctgaac gaatcgaaaa
    21481 gatggaattg tcaaaaagaa gtcttaaacg tggttctcgt gtcctagtcg ttgatgattt
    21541 tatgaaaggc ggcggcacag tcaatggaat gaagagcttg atcgaagagt ttgaatctga
    21601 acttgtagga atcaccgttt ttgcagaatc caaatttaat ggtcatcgtg caattgacga
    21661 ttatacttca ttactatacg tgaaagatgt cgacacgaag accaaaaaca ttacagttgt
    21721 accaggaaat tatttcaaag attagagatt gaaaatttat ctatttgccg atcaataata
    21781 gctggaagag attgtgacag aagtgtccag ctctgagaaa taagccggag aatccgaaaa
    21841 tagtttcacc tattttggga attctttggc ttattttcga tagaaacact acaacaacaa
    21901 gcaacaacaa atcagatatc cagctgttat ctgtcagatg agagaaattc gttctccttt
    21961 ttcatataac cctatttttc tctcactatt gttgattgac taattgattt tttaaccccc
    22021 aagaaaaaaa tggtctagtt acaaatatag tctgcttggt tgaaaaattg agtagagtgg
    22081 gctaaactta aaaccatcaa atacaattag gagtgacgca gttggacgca cgttatgcaa
    22141 tcattttggc agcgggaaaa ggaactcgca tgaagtcaaa attatataaa gttttacatc
    22201 cagtttcagg acagccgatg gtggaacata ttatcaatcg agtaagtgaa accaacccag
    22261 atcaaatcat cacgatcgtc gggcatggcg ctgagcaagt aaaggcacag ttgggtgaac
    22321 gtagtgaata cgctctgcaa gcagaacaac ttggtacagg tcatgcagta ttacaagccg
    22381 catctttttt acaagggaaa gaaggaacga cactggtgat cagtggcgac acaccgcttt
    22441 taaccactga aacattgaac aatttatttg agtatcacca aggaaaaaat gcgagtgcca
    22501 cgattctaac cgcacaagcc gaagatccaa ctggatatgg ccgtatcatt cgtgaccata
    22561 ttgggatcgt tgaaaaaatc gttgagcaaa aagatactac accagaagaa gcattggtcc
    22621 aagaaatcaa tacaggaact tattgttttg acaatcaagc tctgtttgaa gcattgaaca
    22681 aagtaggaac agacaatgca caaggggagt actacttgac cgatatcatt gaaatcctca
    22741 aagatgctgg aaaaacagta gcagcttatc agacagaaga ctttgacgaa tcaatgggag
    22801 tcaatgatcg tattgcatta gctaaagcta atgaattgat gcgccaaaga atcaacaaaa
    22861 tgcatatggt caatggtgta agttttgttg atccagcaac gact
//
