LOCUS       NZ_CP070896            44494 bp    DNA     circular CON 17-JUN-2024
DEFINITION  Lacrimispora xylanisolvens strain ASCUSBR21 chromosome, complete
            genome.
ACCESSION   NZ_CP070896
VERSION     NZ_CP070896.1
KEYWORDS    RefSeq.
SOURCE      Lacrimispora xylanisolvens
  ORGANISM  Lacrimispora xylanisolvens
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Lacrimispora.
REFERENCE   1  (bases 1 to 5633035)
  AUTHORS   Gaffney,J.R. and Embree,M.
  TITLE     Hungatella xylanolytica ASCUSBR21
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5633035)
  AUTHORS   Gaffney,J.R. and Embree,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-FEB-2021) R&D, Ascus Biosciences, 6450 Lusk Blvd E209,
            San Diego, CA 92121, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-MAY-2019
            Assembly Method                   :: Canu v. 2.1.1
            Assembly Name :: Hungatella xylanolytica ASCUSBR21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_017084465.1-RS_2024_06_17
            Annotation Date                   :: 06/17/2024 10:45:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,443
            CDSs (total)                      :: 6,353
            Genes (coding)                    :: 5,667
            CDSs (with protein)               :: 5,667
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 686
            CDSs (without protein)            :: 686
            Pseudo Genes (ambiguous residues) :: 0 of 686
            Pseudo Genes (frameshifted)       :: 599 of 686
            Pseudo Genes (incomplete)         :: 95 of 686
            Pseudo Genes (internal stop)      :: 24 of 686
            Pseudo Genes (multiple problems)  :: 30 of 686
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:11:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 896924
            Orig. end                         :: 941418
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070896.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..44494
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="deazapurine"
                     /product="t3nrps-iterative"
                     /region_number="3"
                     /rules="(GTP_cyclohydroI and PTPS and QueE and QueC and not
                     (dpdA1 or bTGT))"
                     /rules="(AMP-binding and PP-binding and (DUF98 or
                     Orn_Arg_deC_N or Orn_DAP_Arg_deC) and not ATP-grasp)"
                     /tool="antismash"
     cand_cluster    1..44494
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /detection_rules="(AMP-binding and PP-binding and (DUF98 or
                     Orn_Arg_deC_N or Orn_DAP_Arg_deC) and not ATP-grasp)"
                     /kind="neighbouring"
                     /product="deazapurine"
                     /product="t3nrps-iterative"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22404
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /kind="single"
                     /product="deazapurine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22404
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:12404](-)"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12404)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
     gene            complement(558..1013)
                     /locus_tag="JWH23_RS05040"
     CDS             complement(558..1013)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024829.4"
                     /locus_tag="JWH23_RS05040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_277408213.1"
                     /transl_table=11
                     /translation="MEIKVADMDIDQVKTGTEVQVNLQTLGENLKGSISDISAVSDSSS
                     GMFLVTVSLGEESTNSAIGLMADIRLSDNKEENSVYIPAKSVQSDDSGTYVYKAADTSA
                     VKVPVTLGKKKNAYIEVTQGLSTGDLVILQSSKPLTDGEKISILTVK"
     gene            complement(1004..1729)
                     /locus_tag="JWH23_RS05045"
     CDS             complement(1004..1729)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024923.4"
                     /locus_tag="JWH23_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="WP_277408214.1"
                     /transl_table=11
                     /translation="MKKITAVLMVTAMLSSALAGCAGAGKQTEVTVAAAKEGKDLSAMV
                     WQGTVEALSSVDIIPVASGKVTQILAKEGDHVEAGAPLFQIDNQDASLQLEQAKASFQS
                     AQASYDSAQKANQLNTVVKPAQITFTTASDNFNRIKVLYESGDVSQADYEAAKAQVDVA
                     QVQLQAAQNSQATTTEVTKAQLESARATLNIAQKRYDDCMVSSPIKGLVTKINVEAGQT
                     VSPQIKAATVIDDSGKKWK"
     cand_cluster    1570..44494
                     /SMILES=""
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and PP-binding and (DUF98 or
                     Orn_Arg_deC_N or Orn_DAP_Arg_deC) and not ATP-grasp)"
                     /kind="single"
                     /product="t3nrps-iterative"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1570..44494
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[21569:24494](+)"
                     /cutoff="20000"
                     /detection_rule="(AMP-binding and PP-binding and (DUF98 or
                     Orn_Arg_deC_N or Orn_DAP_Arg_deC) and not ATP-grasp)"
                     /neighbourhood="20000"
                     /product="t3nrps-iterative"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      21570..24494
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(AMP-binding and PP-binding and (DUF98 or
                     Orn_Arg_deC_N or Orn_DAP_Arg_deC) and not ATP-grasp)"
                     /neighbourhood="20000"
                     /product="t3nrps-iterative"
                     /protocluster_number="2"
     gene            complement(1744..2433)
                     /locus_tag="JWH23_RS05050"
     CDS             complement(1744..2433)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF027890.4"
                     /locus_tag="JWH23_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="WP_277408215.1"
                     /transl_table=11
                     /translation="MQENKHINIEDQEISKGSGKLKKVLIPLLLAVILLGGAAAGYFYY
                     VSTNYFKTDNARVTAKLYSVKAVANGKLLSWEVENGDLVEQDQVLGREETLPYITSPIT
                     GTVVKNEGAANQAVAMGSELAVVADTSDLYIGVNVEETDIMKIKLGQKVDIKLDAYPGK
                     LFKGQVIEIDPATQTYFSGGTSFTTSGDYTKVTQLIPIKVAIENQQNLPLVFWNECFCK
                     NSFKIIV"
     gene            complement(2448..4289)
                     /locus_tag="JWH23_RS05055"
                     /pseudo=""
     CDS             complement(2448..4289)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008716847.1"
                     /locus_tag="JWH23_RS05055"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSEEKSSGGPMGRGGGLGQKTEKAKNFKGTMLHLAGYLKHYKVSV
                     IVVILFACCSSVFSIVGPKVLGKATTKLFEGLMAWAMGTGLLTDFRYIRNRLLLLVVLY
                     LVSALFSYLQSYIMSGGQYEDHL"
     gene            complement(4286..5962)
                     /locus_tag="JWH23_RS05060"
                     /pseudo=""
     CDS             complement(4286..5962)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008716845.1"
                     /locus_tag="JWH23_RS05060"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLLLFGQAACDLSLPDYMSDIVNKGITSGDTMYIVKAGFQMMGIA
                     FLSAFCTVIVGLIGARMAAGICRNLRQDVFTRIESFSSAEMEKYSTSSLITRTTNDITQ
                     IQQLIVMLIRIVFYAPILGVGGVIHALEKDKSMSWIIALSVGLLLVMIFP"
     gene            complement(6041..6538)
                     /locus_tag="JWH23_RS05065"
     CDS             complement(6041..6538)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024854.4"
                     /locus_tag="JWH23_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_277408216.1"
                     /transl_table=11
                     /translation="MLDEKEKYIKKVKTHLAVMMGKGRKVDKILLSHGLTRLELFAIQQ
                     IYEATNADQEQKGIYVSALAKKMDIVLPSASRTLNSLEKRGLISREIDPDNRRNICVML
                     TEKGYIVRKKCLEKVNLLVGRVVEGMGMEDMDQLITLWNRFIDQMERAVNDMTEEIDEM
                     TD"
     gene            complement(6713..7015)
                     /locus_tag="JWH23_RS05070"
     CDS             complement(6713..7015)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006876965.1"
                     /locus_tag="JWH23_RS05070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3892 domain-containing protein"
                     /protein_id="WP_277408217.1"
                     /transl_table=11
                     /translation="MSENQTKGAGAELAMMALDDIPSPKADAKEIVALVKESGRVTGYQ
                     LSDGRTLNKEEGVMLARQGEIKGVGVASRNGNEYLKSLPDGTENNNLSNLPSVKN"
     gene            7176..8423
                     /locus_tag="JWH23_RS05075"
     CDS             7176..8423
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013810.4"
                     /locus_tag="JWH23_RS05075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="triacylglycerol lipase"
                     /protein_id="WP_277408218.1"
                     /transl_table=11
                     /translation="MTYIERTTRYFFLMLLYNLVLLSPMMPDKLIRVLSCTGLMLFYLY
                     CHIKPVNTSCKEQRLKILHGGYELVLASIVTFLIETAIYLFLIFKTTTPARLLIMNGII
                     CAILLYLLFMNGIIRIFTCSGQLGFFKRIALLLFWWIPGFNLFLLHSFMEVSRKEYDFS
                     MEKQQFYEKWKEEELCKTKYPILMVHGIFFRDWKNFNYWGRIPDELIRHGATIFYSNHQ
                     SSASVEQCAEEIKACILKIVKDTGCGKVNIIAHSKGGLDSRYAVSCLGMDGYVASITTI
                     NTPHYGCNYVCRILDRISPEFVKFIGKKYESLFTLLGDDNPDFLSGLRDLTDRECARLN
                     GVMTDAPGVYCQSTGSQMGSAKKCHVSFESGLSDHSDSWGRQERRSGFNQFHGMGKRFR
                     RSETKRKAGNLSWRCH"
     gene            8535..9293
                     /locus_tag="JWH23_RS05080"
     CDS             8535..9293
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017856.4"
                     /locus_tag="JWH23_RS05080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aromatic acid exporter family protein"
                     /protein_id="WP_277408219.1"
                     /transl_table=11
                     /translation="MNKDTIIKSLKIAVAAVLSIAIAGELGLRYSATAGIITVLSIQNT
                     KKETIKSARNRTLAFVCALLIARLLFGILGFTLPAFAGYLFLFALLCFYADWGEAIAMD
                     SVLITHFLTERSMTAALVANEAALFLIGTTVGILVNLHLRRRKDEFKKLSDEVDTRIKD
                     TLSQMSCFLGTEDKDSCRPADLLSLQKALRTAKACALTNYNNALFKKKIPTKLIILKCA
                     GSKVSCFTKSMKISGPFPVFQKKQWKFLSC"
     gene            9194..9499
                     /locus_tag="JWH23_RS05085"
     CDS             9194..9499
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023156.4"
                     /locus_tag="JWH23_RS05085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_277408220.1"
                     /transl_table=11
                     /translation="MRRQQSLLLYEIYENIRSISCLPKEAMEVSELLARIEQGYHRDNS
                     VEGLLKDLNLLLLDLKDHELPISREEFEARAILFYILKQLHRLLLIKREFILNHSS"
     gene            complement(9502..9999)
                     /gene="queF"
                     /locus_tag="JWH23_RS05090"
     CDS             complement(9502..9999)
                     /EC_number="1.7.1.13"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0033739 - preQ1 synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013496963.1"
                     /locus_tag="JWH23_RS05090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="preQ(1) synthase"
                     /protein_id="WP_277408221.1"
                     /transl_table=11
                     /translation="MSGRNSEETKGVTHLGSQGTVYETDYNPGVLETFLNKHPNNDYFV
                     KFNCPEFTSLCPITGQPDFASITISYVPGEQMVESKSLKLYLFSFRNHGDFHEDCMNII
                     MKDLIALMHPKYIEVWGKFTPRGGISIDPYCNYGKPGTRWEEVAWERLKNHDLYPERVD
                     NR"
     gene            complement(10001..10690)
                     /gene="queC"
                     /locus_tag="JWH23_RS05095"
     CDS             complement(10001..10690)
                     /EC_number="6.3.4.20"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013496962.1"
                     /locus_tag="JWH23_RS05095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="WP_277408222.1"
                     /sec_met_domain="QueC (E-value: 5.8e-60, bitscore: 200.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 5.1e-05, bitscore:
                     21.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVLLSGGVDSATCLGMAIEEYGRKNVCGLSISYGQKHAKELE
                     AAKKIADYYEIEFISLDLSRIFAYSDCSLLTQSQQEIPRESYAKQLENSEGKPVSTYVP
                     FRNGLFLSSAASIALSKGCSVIYYGAHSDDAAGNAYPDCSSSFQEAMSRAVYIGSGNQL
                     TIKAPFVLWTKAEVVERGLMLHVPYELTWSCYEGGEEPCGKCGTCIDRADAFAKNGMKD
                     PALKRGE"
     gene            complement(10724..11291)
                     /gene="folE"
                     /locus_tag="JWH23_RS05100"
                     /pseudo=""
     CDS             complement(10724..11291)
                     /GO_function="GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA]"
                     /GO_process="GO:0042559 - pteridine-containing compound
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="folE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: GTP_cyclohydroI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966889.1"
                     /locus_tag="JWH23_RS05100"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="GTP cyclohydrolase I FolE"
                     /pseudo=""
                     /sec_met_domain="GTP_cyclohydroI (E-value: 8e-11, bitscore:
                     40.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIDTDAIQTHVRGILKALGEDPDREGLKDTPSRVAKMYGEVF"
     gene            complement(11312..11980)
                     /gene="queE"
                     /locus_tag="JWH23_RS05105"
     CDS             complement(11312..11980)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="queE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008401370.1"
                     /locus_tag="JWH23_RS05105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative 7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="WP_277408223.1"
                     /sec_met_domain="QueE (E-value: 3.9e-35, bitscore: 120.0,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.5e-09, bitscore: 36.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-13, bitscore: 50.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADYNVAETFVSINGEGVYAGQLAVFIRFYGCNLSCSYCDTAWAK
                     DALVRGKTMSELDIYEYIKETGIKNVTLTGGEPLIQPGIGDLLSLLLLDEELRVEVETN
                     GSADLSTYQRETNALTFTMDYKLPGSKMETAMQLSNFDYLKQKDTVKFVAGSITDLRRA
                     VEVIDRYQLSGRCHLYFSTVFGSISLPDVVEFMKQNQLNDVTLQLQMHKIIWGSDAVGV
                     "
     gene            complement(11967..12404)
                     /gene="queD"
                     /locus_tag="JWH23_RS05110"
     CDS             complement(11967..12404)
                     /EC_number="4.1.2.50"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: PTPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004451706.1"
                     /locus_tag="JWH23_RS05110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="WP_277408224.1"
                     /sec_met_domain="PTPS (E-value: 2.8e-30, bitscore: 103.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYLETEQSFDSAHFLKGYDGKCKNIHGHRWRVVIEIESPTLQKE
                     GQTQGMIVDFSRLKQDLKEETDYFDHSLIMETGSLKPDTLTALKKEEFLLVEVNFRPTA
                     EEFSRYFYERMSQRGYEVKSAKVYETPANCASYGEDSHGRL"
     gene            complement(12665..13945)
                     /locus_tag="JWH23_RS05115"
     CDS             complement(12665..13945)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013714.4"
                     /locus_tag="JWH23_RS05115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_277408225.1"
                     /transl_table=11
                     /translation="MKARQEWNRAVQKFPEVIVYCSQISDIQNAVHYARRHEMGIRIRS
                     GGHHYQGYSTGNGVLVIDVSQMKDIRLSGSGQCIVMESGVQNREVYNFAGEKGYPFPGG
                     TCPTVGAAGYTLGGGWGYSSRFLGLGCDSLKAVEIVNYEGKVLTADETCNPDLFWALRG
                     AGGGNFGVVTSLKYKLPPRITAVTLVDLEYIKPGLEEMAGFLGVWQKWLVGLDPRITMN
                     ISMYNSPQDGLGIFGRGLFYGSAREAATILDPFERDGAVLSYEELSFFQAMEKIQSSYP
                     DSEKFQSTGRFVQRMYGEKERMQIAGLIAERAEGSVYAAVTVYALGGKIREVSPVSTAY
                     FFRDAFYIMGIQSVWENDCYGEINRQWLYPRFQYIKGMTEGSYVNFPYNRLPDYEEEYY
                     GENVCRLRQTESRYDPLHVFSFPQAIR"
     gene            complement(14092..15465)
                     /locus_tag="JWH23_RS05120"
                     /pseudo=""
     CDS             complement(14092..15465)
                     /GO_function="GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009172721.1"
                     /locus_tag="JWH23_RS05120"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="6-phospho-beta-glucosidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKGKIKIVTIGGGSSYTPN"
     gene            complement(15470..16339)
                     /locus_tag="JWH23_RS05125"
     CDS             complement(15470..16339)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013577.4"
                     /locus_tag="JWH23_RS05125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="WP_277408226.1"
                     /transl_table=11
                     /translation="MTLFSRQVMEQFGELDYEVYNYILRNSEKIPYMTIREVAKEAHVS
                     TTTITRFCRKTMCSGFSEFKVRFKLEKEKKGSVKKRFDLSSITDFFERVNSDAFQKQLD
                     TIAEVIAGKRQIIFIGSGNSGIMAEYASRYFCNIGIFSTGINGPMFPINLEFPEESIII
                     VLSVEGETNIIIEEFFYIEGEQQHSGIHYKQQEQHSGKNFRLQHFLLYSKRKKRAGRDE
                     GGYHFSDSGSLYRGSPGKADHGKETGIKHPVFFVEQMPKHPCLLPKKVNPFPFRDFWSM
                     LFLSNTWR"
     gene            complement(16367..16591)
                     /locus_tag="JWH23_RS05130"
     CDS             complement(16367..16591)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014615.4"
                     /locus_tag="JWH23_RS05130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="WP_277408227.1"
                     /transl_table=11
                     /translation="MTYNTDTCLPIVAYPNSGETYDACCKTWHGVKEPGQYGQWAAKWY
                     EAGAGLIGGCCRTTPEDIHEIFTWYQKNR"
     gene            complement(16702..17271)
                     /locus_tag="JWH23_RS05135"
     CDS             complement(16702..17271)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608305.1"
                     /locus_tag="JWH23_RS05135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_277408228.1"
                     /transl_table=11
                     /translation="MAIKIFIDQGHNPSGYFNSGAEANGLQESEINYQVGIYLRDLLNS
                     DPRFEARVSRPQPDTVLGTNNTTSLAARVAMANQWPANYFISIHCNLNPNPEINGTEVY
                     IYQYFTQGQWLAEQIMGGINDMVGTRNNGIRENPSLYVLRNADMPANLVELGYISNPSD
                     AEKLENDQYGFAYGIYLGILRYFGFA"
     gene            complement(17369..18211)
                     /locus_tag="JWH23_RS05140"
     CDS             complement(17369..18211)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012058178.1"
                     /locus_tag="JWH23_RS05140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_277408229.1"
                     /transl_table=11
                     /translation="MKQQYMETAKSGKDLIAEINETVPGEGQAAFWWLGQLGYAVKLGT
                     VTIYIDAFLSERPDRRIAPLFDPSEITNADYIIGTHDHLDHIDRNVWHQLSVSSPNALF
                     LVPEKLIPVLSEDLMIDKSRFLGLNDGKIQILKDGIKITGIASAHEFLDQDPVTGQYPY
                     TGVVIEGMGVKLYHSGDTCIYEGLYGKLRSFGDMDVMFLPINGRDGVRYRSNIIGNMTY
                     QEAVDLAGAMKPGLTVPGHYEMFSSNQEDPDRFEDYITIKYPGLPYWLGRHGEKVIYS"
     gene            18562..19317
                     /locus_tag="JWH23_RS05145"
     CDS             18562..19317
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963877.1"
                     /locus_tag="JWH23_RS05145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AIM24 family protein"
                     /protein_id="WP_277408230.1"
                     /transl_table=11
                     /translation="MITYKNLYDNGNMLKINERGCVKVFEHQKDLSVEAGSAIASYYAS
                     KMNIRKRQVLIELNGNSFTVQAGAMQWTSGSVSMTSGIKGVGDFLGKALASKVTKESSA
                     KPEFKGSGLLMLEPTYKHILLEEVSEWGSMVLEDGLFLACDSDIKQNVVARTTLTSAVA
                     GKEGFFNLCLTGQGIAVLESPVPREELIEFELKDDEIKIDGNMAIAWSNSLKFTVERSS
                     KSLIGSAVSGEGLVNVYRGTGKILMAPVG"
     gene            19533..20246
                     /locus_tag="JWH23_RS05150"
     CDS             19533..20246
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776502.1"
                     /locus_tag="JWH23_RS05150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_277408231.1"
                     /transl_table=11
                     /translation="MSSIQQILVVDDDADIREVIRIQLENKGYLVLEAANGSDAVNTVR
                     ENPDIDLIILDIMMPGMSGIEACAQIRTFHSAPVLFLTAKSKETDKNDAYENGGDDYLV
                     KPFSQAELFMKIQSLLRRYVVYKGKSESSVNLSEVHVQDIVIDTVNHWVYRENQKIELT
                     DTEYLVLMYLVKNKGTAKDAQAIYEGVWNEKFLPSSTNTIMVHILKLRKKLELDFNNPL
                     IIRTVWGKGYQIDEG"
     gene            20236..21573
                     /locus_tag="JWH23_RS05155"
     CDS             20236..21573
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012722.4"
                     /locus_tag="JWH23_RS05155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_277408232.1"
                     /transl_table=11
                     /translation="MKGKTLSSLRYKQILVLLFGAFLSFAVYLIVGSLGDYMVSKKHMD
                     EDSVQYRLNSYQNSFENYVKKNKISVKNVRAISRWVKNHKYVYLTIYNGDEILYESGYW
                     NDSYSSYETATTIVESCNQKERDIVFSDGTYSVSIIDSSQIKWLDVVLYCSWIMFFIVF
                     FIIIILYNRRIIHRIVLLSKEVSLIEQGNLEQPIFHKGNDEISLLAKNADNMRNSIITR
                     YKSEKDAWEANSELITSMSHDIRTPLTSLIGYLEILDSKDYHSEEQLEKYIKNCKEKSI
                     QLKDLSDKLFQYFLVFGKDTILMNMETFDARILLQQLLSEHVFNLNSLGFEVQTEFMNE
                     PCTILIDIQYLKRLFDNLFSNVRKYAGHGTPVVVKGARDGDNLIISITNEIRTDLVFQE
                     STNIGLKTCGKIAEQMDGSFEILTTESLFTACATFPIKPAGKETQS"
     gene            21570..22934
                     /locus_tag="JWH23_RS05160"
     CDS             21570..22934
                     /NRPS_PKS="Domain: AMP-binding (7-412). E-value: 5.5e-84.
                     Score: 274.0. Matches aSDomain:
                     nrpspksdomains_JWH23_RS05160_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     t3nrps-iterative: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="JWH23_RS05160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_349772901.1"
                     /sec_met_domain="AMP-binding (E-value: 5.3e-86, bitscore:
                     287.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNILEYLEHSAKEFPQKKAVIDPETSCTYEELYDRARRIGSFLS
                     EHTKTGKPVVVFMDKCVEAVTSFMGIVYAGCFYTFISPDQPVARIGQILDVLKADCMIT
                     LLKTDEKLKQLSFKGTILEYHKLISSPADPERLKAVREKSLDTQPLYCNFTSGSTGVPK
                     GVLVSHRSVIDFMEYFPDLFGITGDDILGNQAPLDFDVSVKDLYSAFKTGASIVLIPKK
                     YFSIPTMLLDCLCEYQITTLIWAVSALCMVTQLKGFTYKVPEHVNKVLFSGEAMPASHL
                     AIWQKNLPNARFVNLYGPTEITCNCTYYPVLRVFEPEEKIPIGTSFPNEHVFLLGSDDE
                     LITSEGEIGEICVAGTALALGYYNNPEQTKKAFVQNPLNDLYPETIYRTGDLAFYNSHG
                     ELCFSGRKDFQIKHMGHRIELEEIELILNSYPEISRACCAFDSEKTALLHFTAGI"
     aSDomain        21591..22805
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JWH23_RS05160_AMP-binding.1"
                     /evalue="5.50E-84"
                     /label="JWH23_RS05160_AMP-binding.1"
                     /locus_tag="JWH23_RS05160"
                     /protein_end="412"
                     /protein_start="7"
                     /score="274.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LEHSAKEFPQKKAVIDPETSCTYEELYDRARRIGSFLSEHTKTGK
                     PVVVFMDKCVEAVTSFMGIVYAGCFYTFISPDQPVARIGQILDVLKADCMITLLKTDEK
                     LKQLSFKGTILEYHKLISSPADPERLKAVREKSLDTQPLYCNFTSGSTGVPKGVLVSHR
                     SVIDFMEYFPDLFGITGDDILGNQAPLDFDVSVKDLYSAFKTGASIVLIPKKYFSIPTM
                     LLDCLCEYQITTLIWAVSALCMVTQLKGFTYKVPEHVNKVLFSGEAMPASHLAIWQKNL
                     PNARFVNLYGPTEITCNCTYYPVLRVFEPEEKIPIGTSFPNEHVFLLGSDDELITSEGE
                     IGEICVAGTALALGYYNNPEQTKKAFVQNPLNDLYPETIYRTGDLAFYNSHGELCFSGR
                     KDFQIK"
     CDS_motif       22020..22076
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JWH23_RS05160_0001"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="JWH23_RS05160"
                     /protein_end="169"
                     /protein_start="150"
                     /score="26.7"
                     /tool="antismash"
                     /translation="YCNFTSGSTGVPKGVLVSH"
     CDS_motif       22605..22688
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JWH23_RS05160_0002"
                     /evalue="1.40E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="JWH23_RS05160"
                     /protein_end="373"
                     /protein_start="345"
                     /score="36.6"
                     /tool="antismash"
                     /translation="GEIGEICVAGTALALGYYNNPEQTKKAF"
     CDS_motif       22776..22841
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_JWH23_RS05160_0003"
                     /evalue="1.90E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="JWH23_RS05160"
                     /protein_end="424"
                     /protein_start="402"
                     /score="26.6"
                     /tool="antismash"
                     /translation="FSGRKDFQIKHMGHRIELEEIE"
     gene            23071..23748
                     /locus_tag="JWH23_RS05165"
     CDS             23071..23748
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     t3nrps-iterative: Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014803.4"
                     /locus_tag="JWH23_RS05165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alanine racemase"
                     /protein_id="WP_277408233.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.5e-12, bitscore:
                     45.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSEVNESKLKTALANYKTPFYLFDTDILANRIADIRSALPPKTQ
                     ICFAMKANPFLVKDMEMHVDYFEVCSPGEFHICERAGIDEKRIVMSGVYKKQEDMEYAI
                     SRYKDIIFTVESMEHWKILTSCALKEKRNIRVLLRLTSGNQFGMDESSIRRIIMEKPCE
                     YVEILGLQYFSGTQKKSGAKLESELMMLDQLCVDLKNQYQFTVKKLEYGPGLPVCYFEG
                     EKR"
     gene            23729..24262
                     /locus_tag="JWH23_RS05170"
     CDS             23729..24262
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     t3nrps-iterative: Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012500.4"
                     /locus_tag="JWH23_RS05170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_277408234.1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 8.3e-17,
                     bitscore: 59.8, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGKKDEEEAMLLALSQAIEHLSFQGQVTLEMGRFIAASCGVYAT
                     SVVDLKTNNDQSYCIVDGGIHQLNYYGQMLAMKKPFIKHYGSQNGEVREWTVCGSLCTS
                     SDVLVRQYPFKDLNQGDHLVFGKTGAYSATEGMSMFLSRDLPLVLLYSEHEQYRIARAS
                     LATDQFNFFHSERG"
     gene            24267..24494
                     /locus_tag="JWH23_RS05175"
     CDS             24267..24494
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     t3nrps-iterative: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147: putative acyl carrier protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007862086.1"
                     /locus_tag="JWH23_RS05175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_277408235.1"
                     /sec_met_domain="PP-binding (E-value: 2e-05, bitscore:
                     23.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLLEILNEINPGIDYETETRLIDDALLDSFSILSLIPELEDAF
                     EVSITPADMIPVNFNSANAIWTMINRLKED"
     gene            24498..24638
                     /locus_tag="JWH23_RS05180"
     CDS             24498..24638
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JWH23_RS05180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_277408236.1"
                     /transl_table=11
                     /translation="MTYTSILYLFIFLPGVMLLYQLAPGRHRYKVLLAASWLFFFPSAE
                     N"
     gene            24785..25672
                     /locus_tag="JWH23_RS05185"
     CDS             24785..25672
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015049.4"
                     /locus_tag="JWH23_RS05185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBOAT family O-acyltransferase"
                     /protein_id="WP_277408237.1"
                     /transl_table=11
                     /translation="MWLGLGIQLGMLVVLKYSGFFSDNINHLLKAVSYPNLLPAMKFAL
                     PIGISFYTLQAVSYLADVYYEKIPADDHLGRLALYLTFFPILMEGPVCRYSQTANALTE
                     GKPLEYKNVTYGFQRILWGLFKKLIIADRLNLLVETVFGSYNQYGGIVVILGAILYTFQ
                     LYADFSGCIDMTIGTGEIFGITIPENFRQPFFSKSPSEFWRRWHITLGTWLKDYVFYPI
                     SLTAPVKKFGKNSRAKLGKHVGQVVASAPALFWCMALQWFLAWHRLALSVFRYVLLCPD
                     LTGELNGTFCNKSS"
     gene            25776..26081
                     /locus_tag="JWH23_RS05190"
     CDS             25776..26081
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JWH23_RS05190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_277408238.1"
                     /transl_table=11
                     /translation="MTAGLSMFQSIFTGFDTKVLTDGSLLQLGLSLADYTAVFLGFLAV
                     LTVGIIHERGISIRDKISGYKIPVRWTLYYGAILLVIVLGAYGDGYLPAKMIYAGF"
     gene            26093..27064
                     /locus_tag="JWH23_RS05195"
     CDS             26093..27064
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JWH23_RS05195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_277408239.1"
                     /transl_table=11
                     /translation="MHAGNKIRTLAFITGLTLLLYIMSFLFLPANTGAEGLYKKAGGIY
                     KEPKNTIGYLSIGDSESSTSISPLEIWNTYGYTGFNLGVPAQRLQDTYYLLEKVLSKQS
                     PKVVLLETNACFRDFKYINALETIIDDKTKKIFPIYQYHNNWRYFHFYMLKNLSADMAE
                     KPSPAYKGYQYNINSKPYIGGPYTEETDEIEVIQDQPYLYLTKISELCKEKGIRLVLYS
                     SPSPKCWTYAKHNAVKQFADKNDLDYIDFNLSLDQLSIDWNTDTRDGGDHINYYGAKKV
                     SDYMGSYLSGLNLLTDHRQDPRFVSWNNEFKTYETQTMRSSK"
     gene            complement(27110..28326)
                     /locus_tag="JWH23_RS05200"
                     /pseudo=""
     CDS             complement(27110..28326)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (63-205). E-value: 2e-29.
                     Score: 94.7. Matches aSDomain:
                     nrpspksdomains_JWH23_RS05200_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002850965.1"
                     /locus_tag="JWH23_RS05200"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /pseudo=""
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.2e-27, bitscore:
                     94.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1e-06, bitscore:
                     26.8, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKFEKSKKLDYVCYDIRGPVMDEANRMIAQGVEILKLNIGNPAP
                     FGFRAPEELLMKMNSNLVHTEGYSDSRGLLSAREAIVKYCRKKGIEEVGTDDVYTGNGV
                     SELITLSMQGLLDSGDEILVPSPDYPLWTASVTLAGGTAVHYICDEAADWYPDINDIKS
                     KITERTKGIVVINPNNPTGTLYSKELLEEIVKLCRENGLIILLMRSMTDWFLTVWSIHP
                     LLHLLLISLRLRLTVCPSPI"
     aSDomain        complement(27712..28137)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JWH23_RS05200_Aminotran_1_2.1"
                     /evalue="2.00E-29"
                     /label="JWH23_RS05200_Aminotran_1_2.1"
                     /locus_tag="JWH23_RS05200"
                     /protein_end="205"
                     /protein_start="63"
                     /score="94.7"
                     /tool="antismash"
                     /translation="HTEGYSDSRGLLSAREAIVKYCRKKGIEEVGTDDVYTGNGVSELI
                     TLSMQGLLDSGDEILVPSPDYPLWTASVTLAGGTAVHYICDEAADWYPDINDIKSKITE
                     RTKGIVVINPNNPTGTLYSKELLEEIVKLCRENGLIIL"
     misc_feature    28380..28395
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.14"
                     /tool="antismash"
     misc_binding    complement(28382..28620)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            complement(28664..29197)
                     /locus_tag="JWH23_RS05205"
     CDS             complement(28664..29197)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007062945.1"
                     /locus_tag="JWH23_RS05205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_277408240.1"
                     /transl_table=11
                     /translation="MRSLKYAILGLLCRHPMTGYEIAKEFNSELAEFWYANHSQIYPEL
                     KKLNDEGLVSYDIEISGEILEAKRYTITEDGYEDFAKWLNKDEKMQKTPKDIFRLRMYF
                     SGNMNVETRLRLLESQRIQHVKRLNTLKKKNEPYTEVPPRESDRFGDFLVLQGAIMRQE
                     NIIAWIDKCISYCK"
     gene            29369..29611
                     /locus_tag="JWH23_RS30970"
     CDS             29369..29611
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JWH23_RS30970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_349772902.1"
                     /transl_table=11
                     /translation="MNYNKKRWLILIASCLINLCIGSLYAWSVLSVPMAEHLSQITGMK
                     LTARDLSIVFVIANAVGPITMITGGTINDTLWARN"
     gene            29632..30186
                     /locus_tag="JWH23_RS30975"
     CDS             29632..30186
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="JWH23_RS30975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_349772903.1"
                     /transl_table=11
                     /translation="MFGGGMFLSGYANSVNFLIGTYSILLGLGLGMVYGATISTSIKFF
                     PDKRGLVGGLTTATFGISSVIIPPIAAMIISTTGVTSAFKIIGAVFTVIICLGAFFMEK
                     CPADFVPEGYTPPSAGKQAAMNKNWKEMLQTPVFYVMIVLLTCGAFAALMFIPNGFPSG
                     SEHRGNVCCFSNSCRFYPGII"
     gene            30137..30604
                     /locus_tag="JWH23_RS30980"
     CDS             30137..30604
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="JWH23_RS30980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_349772904.1"
                     /transl_table=11
                     /translation="MSVVSATAAVSTLALFNVLGRILAGSISDKIGRINTLALACVMSV
                     IGLILLYFCDKGDVVLFYIAISVIGICFGAFMGVFPGFTADQFGPKNNSVNYGIMFIGF
                     ALAGTVGPIILNKIFAATGSYKNAFLTAMVISLAGLGLTFVYRSIHKSKAA"
     gene            complement(30686..31681)
                     /locus_tag="JWH23_RS05215"
     CDS             complement(30686..31681)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009169869.1"
                     /locus_tag="JWH23_RS05215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_277408241.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 8.3e-20, bitscore:
                     70.2, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 6.3e-12,
                     bitscore: 44.1, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGIVGSGIIVKDFLSIAHHLKHTTILSLCSTKRSEEDARALAK
                     EYLIGQVFTDYEDFLKSEADTVYLGLPNHLHFSYAYQALLAGKNVIVEKPFTPTIEQAT
                     VLSRTARERHLFLFEAVTTLYQPDYRRVKELIPSLGSVRLVRCSYSQYSRRYDRFKNGE
                     VLPAFDPACAGGALMDINIYNLHYAAGLFGMPESVHYFANIERGIDTSGVLLLDYGSFL
                     CTLTGAKDCSAPNSCIIQGDKGYLIQDSPANICEGGRVILNDGSEETVADHSYSHRMIS
                     EFLEFEKMILSGDLATCYRYLDHTLCVCEILTQARRMAGIVFPADGQEVQ"
     gene            complement(31678..32232)
                     /locus_tag="JWH23_RS05220"
     CDS             complement(31678..32232)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009003055.1"
                     /locus_tag="JWH23_RS05220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbonic anhydrase"
                     /protein_id="WP_277408242.1"
                     /transl_table=11
                     /translation="MLEEILEYNKEFVKNKNYEKYITNKYPEKKTAIVSCMDTRLTELL
                     PAALGFKNGDAKIIKNAGGVISHPFGSVMRSLLIGIYELDVREILVIGHTDCGARYTDS
                     SKLIELMKGRGIRQKDIDLIKYYGIDFESWLGGFKDLDQSINKSVELIRNHPLVPEEIR
                     VYGLVIDSVTGELSKVEEKGL"
     gene            complement(32257..33630)
                     /locus_tag="JWH23_RS05225"
     CDS             complement(32257..33630)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JWH23_RS05225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_277408243.1"
                     /transl_table=11
                     /translation="MFRENNGSRIHSCNDGDPAPRRYLNPADIYIVKGYGIEVFLENLN
                     SPAGIVFDEEGSLYIADSGLSTGNPQVLKLVNGELELIAEDFVTPISGINYLNGVLYVS
                     HRGFVTRIFRDGQRQNIIMGLPSNGDHYNGPVAFSPDYKIYFGQGTVTNSGVVGNDNDW
                     VPVSPLLCDYTGDYVILTGQNFTTDNILTEAVTDDPAYTGAFSPYGIPNIEFEIRKKYT
                     KASGSILRANLDGSNLEQVAWGFRNPIFLKFNNSGQLYAVNNGFNPVGSRPIENATDDF
                     YYITPDLWYGWPDYSGGEPVNSPRFTPTGGYQPTLLLKNQPNIPPRPYVTFPPNSTLMS
                     FDFNYNQKFGAYGDVYVAEYGSTIRTAVGDGLSYAGAGHRISKIDLRARTISTFAINMS
                     GFPASLSKGGGLERPSHLMFGPNESMYIVDMGLNIEGDPNIFVPGTGVIWRVFRTNDE"
     gene            complement(33680..34158)
                     /gene="msrB"
                     /locus_tag="JWH23_RS30985"
                     /pseudo=""
     CDS             complement(33680..34158)
                     /GO_function="GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008420302.1"
                     /locus_tag="JWH23_RS30985"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDKSKKFPPKSQDELKNELTTIQYQVTQNNATEAPFQNEYFDEFR
                     ERESMWM"
     gene            complement(<34255..34656)
                     /gene="msrA"
                     /locus_tag="JWH23_RS30990"
                     /pseudo=""
     CDS             complement(<34255..34656)
                     /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_function="GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrA"
                     /inference="COORDINATES: protein motif:HMM:NF013766.4"
                     /locus_tag="JWH23_RS30990"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKEIYLAGGCFWGTEKYLENIPGILNTEVGYANGTTKNPTYEEV
                     CYNNTGHAETVKVEYEDTVIGLPYILKLYYDVINPVSVNRQGGDTGTQYRTGIYYTDEG
                     DKPVIEKSVEELQKNYKEKIAIERLPLTNY"
     gene            complement(34683..35294)
                     /locus_tag="JWH23_RS05235"
     CDS             complement(34683..35294)
                     /EC_number="3.6.1.55"
                     /GO_component="GO:0005777 - peroxisome [Evidence IEA]"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003986 - acetyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008413 - 8-oxo-7,8-dihydroguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA]"
                     /GO_function="GO:0010945 - coenzyme A diphosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030145 - manganese ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0035539 - 8-oxo-7,8-dihydrodeoxyguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0015938 - coenzyme A catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.4"
                     /locus_tag="JWH23_RS05235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CoA pyrophosphatase"
                     /protein_id="WP_277408244.1"
                     /transl_table=11
                     /translation="MDRQTFSRRKPGMVEEEKYRKYAVLIPVLTIDGAKYLLFEKRSSN
                     LKHQPGEICFPGGKLEPGETLKKCAVRETMEELNVTSGQIKVLGPGDIYISPFRLIIHS
                     FIGELRDYQDTFSTDEVEEIIKVPLDYLKSITPETYESMLITETPEDFPYEWIPGGNQY
                     SWTKGTRDILFYRYENWVIWGDDGADSPVGSGTDEAISFI"
     gene            35431..36324
                     /locus_tag="JWH23_RS05240"
     CDS             35431..36324
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022604.4"
                     /locus_tag="JWH23_RS05240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2935 domain-containing protein"
                     /protein_id="WP_277408245.1"
                     /transl_table=11
                     /translation="MTSKESYIQCSLQYHLFWIRILKEHAIFIEATMPPPGKEYADQAD
                     TYKQQYDQLLEVAIKLSNGVIPLSVLESGQFYTQYTEEAERLAQLNTGITINSQLTRMA
                     YDIVPCTADYTATNKNEQDVFMLNQNLLNLTTSFVQFQADLLNKRVSCGLFTMMYTGDI
                     LHILMEAKRYLEILKRLQSRDDSLLSDYKSFWSHNMADHAKVMRGQLDPTETSYFNAAN
                     QFANTFDQLSTAEMNPDTFPSDREILSDAIAISDFKSDTTNGLITCKIQAIMLALYTDH
                     LLREANHFIYLMYAGS"
     gene            complement(36374..38101)
                     /locus_tag="JWH23_RS05245"
     CDS             complement(36374..38101)
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012102188.1"
                     /locus_tag="JWH23_RS05245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GMC family oxidoreductase N-terminal
                     domain-containing protein"
                     /protein_id="WP_277408246.1"
                     /transl_table=11
                     /translation="MENGFDADVIVIGSGGGGAVAAKELGEKGLKVLILEAGPWYGNRK
                     WPEPNTSAGAQESSSNEDLDIQLLKTNFTDLEDDMNDAITGKFRWGPADRSTSPWRRIV
                     EKGGFVWQSAGVGGSTLLYFANCPRAYPAAFERDWPISYEEMIPYYEEVEQTLPVREAT
                     ATSKEDLFLYGARKMGFTYTDEINLTKPGFRLQPNGILGINPMLNNPDFDLENNQAVGC
                     TLRGHCVNGCCIGPNVGSVAKRSTLVSYIPYALATGNVDIMPNSFVTAIHTGQNEEEGL
                     FASSVTVRNTWTGEIREFKAKVIVLSAGSIESPRLWLNSGLPENEWVGKGLTTHMIDCV
                     SGIFEEEDLMNILGMSEVKPYVGQNSAARMDYPGLGAFEPFGTSPGINSTMIYGTSQKG
                     YYFQNQTREEEAWDREGIIAGELLKEFMRNYNKTLSIVVFSDDDVSQKNGVTLDPERRD
                     ENGYIPVISYEISDADRERRDQLVGLAAEVLKKAGAKTVSRANWPPDVCAHIMSTMRIG
                     FVTDTICEAFQVKRLFIADNSVLCNGLGGPNPTLTTQALAVRTAQKIAEKYFPSAKKA"
     gene            complement(38128..38820)
                     /locus_tag="JWH23_RS05250"
     CDS             complement(38128..38820)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JWH23_RS05250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_277408247.1"
                     /transl_table=11
                     /translation="MILFSKVFIVFYEHAFWKESGGTLAENSDGLKNGLWDENSVYDYV
                     VNTMKAYADAMVPHSPDLAELYGRIQFYGAVESYTAEYLIMSLDSYPTPFAVAVAEILN
                     MAAKQYLMEKGEDPDVPKDSGGLYFSKLSQEDRLKIVDRISSPGGIIYVPAGLTMKQED
                     IVPVMSALNRLTLMGYYSEWSGYGSTRFMSPDKRMLEYKPIGWEQVGYPGPSKGYRIAG
                     AFNFAQRK"
     gene            complement(38897..39500)
                     /locus_tag="JWH23_RS05255"
                     /pseudo=""
     CDS             complement(38897..39500)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020814891.1"
                     /locus_tag="JWH23_RS05255"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF6273 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQTGDKISFGNYQWRVLELLEDRALIITEYIIERRPYHNIYKETT
                     WADCAVRAYLNGEFHDRFSVEEQSRMIPVLNRNPDNEWYGCEGGADTRDTIFFIKYGGS
                     SVPVFW"
     gene            complement(39580..40440)
                     /locus_tag="JWH23_RS05260"
     CDS             complement(39580..40440)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015392294.1"
                     /locus_tag="JWH23_RS05260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EamA family transporter"
                     /protein_id="WP_277408248.1"
                     /transl_table=11
                     /translation="MKQMKDILLTMLTPMLWGSTYIIASVLIPIQRPVFVAFMRAFPIG
                     LILLLYYRKLPKGIWILKSLILGSLNIGIFFLFLFIAAYRLPGGIASIIGSVQPVFVIF
                     FSWVLLKEKPTMRSYAAIVMMVTGVILLLFKQQMAIDVWGVLAALCGAVVMALGVVLTK
                     YWGKPEGISQMVFTSWQLFFGSLILIPAVFIMEGSIPALTPVNIAGLAILGVVNTGLAY
                     YLWFRGIEILSPVRVSLLSPVNPLTAFVLGYVVLGQSISPIQLVGVAIIIASIFVSQKK
                     TAKAG"
     gene            40621..41115
                     /locus_tag="JWH23_RS05265"
     CDS             40621..41115
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017810687.1"
                     /locus_tag="JWH23_RS05265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_277408249.1"
                     /transl_table=11
                     /translation="MKKDNVDKIIDQWALELPDLDASPMAVWGRLKRTVKYSERRLAEN
                     FSLYQLNSGEFDVLATLRRSGGEFKLKPTDLYQSLMITSGAITNRIDTLEKKDLVKRVH
                     DSEDRRTIYVQLTNAGYELISRAVISHTQAEEFLLKGLTKEELAQLDQLLKKLLSSLEE
                     Q"
     gene            complement(41132..41584)
                     /locus_tag="JWH23_RS05270"
     CDS             complement(41132..41584)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JWH23_RS05270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_277408250.1"
                     /transl_table=11
                     /translation="MIPEIRNLKEKKSKLEEEIKSFQKDAEELKKIGEAADPKRSTQLS
                     EKGKALVIRKKNLAASEKEINAYMEAVQKTAIQIFYVFKEVSRSAAEGVRTAINRLTGE
                     NRKALRKAEDIQGFTEGRKKLSQLYTLLELLDDCMRIYQKYDRLKS"
     gene            complement(41632..42090)
                     /locus_tag="JWH23_RS05275"
     CDS             complement(41632..42090)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JWH23_RS05275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_277408251.1"
                     /transl_table=11
                     /translation="MGFLVRLLEKGSLKKPLHFTLDKIVEEYIPAGEVPPYAQELKSLA
                     SKINLNLKDIAELAVSVRTEIDQLKDEVETFVVVTEKAKRVQANLNLWNEILNELTWDY
                     SYQDEVTDTDTFVHSKAVEEIPRMHHAITQLLGEKEKSCSWNHSLFFS"
     gene            complement(42200..42724)
                     /locus_tag="JWH23_RS05280"
     CDS             complement(42200..42724)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013259.4"
                     /locus_tag="JWH23_RS05280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_277408252.1"
                     /transl_table=11
                     /translation="MSESMYIRNLSREEGEKLLARMEEINKVTRIGMSVSCVGVPTCQI
                     GVLESQTLLKEINRALMEHNINTDYLPSVSISGCFNSCSRHQVSEIGFAGCKKRISDAP
                     AEAFELHVGGAVEKDKTHMGNCMGALRKEDIPDFMVKLSQVLDTKGMYFMDYLKEYQKE
                     FEDLTKPYLIS"
     gene            complement(42747..42983)
                     /locus_tag="JWH23_RS05285"
     CDS             complement(42747..42983)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JWH23_RS05285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_349773275.1"
                     /transl_table=11
                     /translation="MDCYKKHLAQVKESMDLTINVEAAGICKTEVKVQSADIHTDSSNL
                     IPQKQAGFYTAVIHPQCGQLPVKALEKIISFDG"
     gene            complement(<43014..43067)
                     /locus_tag="JWH23_RS30995"
                     /pseudo=""
     CDS             complement(<43014..43067)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013259.4"
                     /locus_tag="JWH23_RS30995"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFAAEGDYENKGKARLRY"
     gene            complement(43042..43764)
                     /locus_tag="JWH23_RS05290"
     CDS             complement(43042..43764)
                     /EC_number="1.8.7.1"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050311 - sulfite reductase (ferredoxin)
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013259.4"
                     /locus_tag="JWH23_RS05290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrite/sulfite reductase"
                     /protein_id="WP_277408254.1"
                     /transl_table=11
                     /translation="MKEYNEKLKEEIAEFREAGHKFVNKEITSAEFKGKSGGMGVYAQR
                     GGKAFMIRLRIPCGILSFSHLKLIHKFAVQYGLERIHLTTRQAIQLHDLDIDSVCDIME
                     TAIDHGLYTRGGGGNYPRNVALSPLSGVDKTEAFDPTPYAQQVNRYVMERIMEYHLPRK
                     LKIAFSNNEADTANCTINDLGFMAVMDQGTPSFKMYLAGGLGNNPAVALPYDELIPPKS
                     GSVSCGSCYKNICGRRRL"
     gene            complement(43841..44275)
                     /locus_tag="JWH23_RS05295"
     CDS             complement(43841..44275)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (2-139). E-value:
                     1.8e-11. Score: 36.6. Matches aSDomain:
                     nrpspksdomains_JWH23_RS05295_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013484929.1"
                     /locus_tag="JWH23_RS05295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_277408255.1"
                     /transl_table=11
                     /translation="MKEIRTEIRINASASAVWYVLTDFRAFPDWNPFMVYLKGKPAVGE
                     RIEVKMVPPGSKGMVFKPTVLKFQKDKEFRWLGHTGFPGLFDGEHILELIENSDGTTTF
                     IQREKFNGILLPMLKKSLDNGTKAGFEAMNKKLKQICETK"
     aSDomain        complement(43859..44269)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JWH23_RS05295_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.80E-11"
                     /label="JWH23_RS05295_Polyketide_cyc2.1"
                     /locus_tag="JWH23_RS05295"
                     /protein_end="139"
                     /protein_start="2"
                     /score="36.6"
                     /tool="antismash"
                     /translation="EIRTEIRINASASAVWYVLTDFRAFPDWNPFMVYLKGKPAVGERI
                     EVKMVPPGSKGMVFKPTVLKFQKDKEFRWLGHTGFPGLFDGEHILELIENSDGTTTFIQ
                     REKFNGILLPMLKKSLDNGTKAGFEAMNKKLKQ"
ORIGIN
        1 cctctttttc atactctgct ttaaatggca cctgggattc gaaagaaatc agcgtattaa
       61 ttgccttttt gtcacaatca agctttatca ttacagcttt ggcaggatag cttgcaaagt
      121 attctctgga atagcttgct ccgtttacct tgtaacttac attgctcact gactgatcca
      181 gattcaggac acgattgtaa tccgaaggct ccccatcatg atcaaagtcc atatacagat
      241 tacccagagg aagataggat tcattatatt ctcccagcat atgactccgg attaattcct
      301 ctgcctgtac gtactcctcc tgttccacca gtcttcggca ctgttccaga taaggaaatg
      361 catgatgatt gtttttgtca tggcggtaac ctgaccagag actttcctca ttgaggccaa
      421 gacactctct ctttatactt ccccaaatca tggcacccag acttccgttg ccgattggta
      481 gggtttcttc ccacttactc gccggttcag cgtagaatag cttcatatta aatatcccct
      541 tttccagttt taccctgtta cttcacagtc aatatactga ttttttctcc atctgtcaat
      601 ggtttactgc tctgtaaaat aacaaggtca ccggtagaaa gtccctgggt cacttcaata
      661 taagcattct ttttctttcc cagtgtaacg ggaactttca ccgcactggt gtctgccgct
      721 ttataaacat aggttcccga atcatcggac tgaacagact tagctggaat atagacggaa
      781 ttttcctcct tattatcaga gagccggata tctgccataa ggccgattgc gctgtttgta
      841 ctctcctcac ccaaagagac cgtcacaaga aacattccgg aactggaatc actgactgct
      901 gagatatcgc tgatactgcc ctttaaattc tccccaagag tctgaagatt tacctgtacc
      961 tctgttcctg ttttaacctg gtcaatatcc atgtcagcaa cttttatttc cacttttttc
     1021 cgctgtcatc gataacagtg gcggccttta tctggggtga aaccgtctgg cctgcttcca
     1081 cgtttatttt tgtcacaagt ccttttattg gtgatgatac catacagtca tcgtatcttt
     1141 tctgggcaat attaagggtt gccctggcac tttcaagctg ggcttttgtc acctcagtgg
     1201 tggttgcctg gctgttctgt gctgcctgta gctgaacctg agccacatcc acctgggcct
     1261 tagctgcctc atagtctgcc tgggatacgt caccgctttc ataaaggact tttatccggt
     1321 taaaattatc acttgctgtg gtgaatgtga tctgggccgg cttaaccaca gtgtttaact
     1381 gatttgcttt ttgtgcgctg tcataagaag cctgggctga ctggaagctg gcttttgcct
     1441 gctctaactg cagactggca tcctgattgt cgatctgaaa caagggagca cccgcttcca
     1501 catggtcgcc ttctttggct aagatctggg tcaccttacc gcttgcaacg ggaatgatat
     1561 caacgctgct taaagcctct actgttccct gccataccat ggcagataaa tcttttcctt
     1621 ctttcgctgc agcgaccgtt acttctgtct gttttccagc tcccgcacag cctgcaagag
     1681 ccgacgaaag cattgctgtt accattaaaa ctgctgttat cttcttcatc cgttttctcc
     1741 ttatcagact attattttaa atgaattttt acaaaagcat tcattccaaa aaacaagagg
     1801 aagattctgc tgattttcaa tcgctacctt aatcggtatc agctgtgtca cctttgtata
     1861 gtcgccactg gtggtaaaac tggttcctcc tgaaaaataa gtctgggttg caggatcgat
     1921 ctcaattacc tgccccttaa acagttttcc gggataggca tccagtttaa tatccacttt
     1981 ctgtcccagc tttatcttca taatatctgt ctcttctaca tttaccccga tataaagatc
     2041 agaggtgtct gccaccacag ccagttcaga gcccatggca actgcctgat tggcagcccc
     2101 ctcatttttc actacagttc cggttatggg tgatgtgata tagggaaggg tttcctcacg
     2161 tccaagcacc tgatcctgtt ccaccagatc tccattttcc acttcccagg ataaaagctt
     2221 accatttgct acggctttta ccgaatacag ctttgctgtc actctggcat tgtcagtttt
     2281 aaaataatta gtgctaacgt aatagaaata tcctgcggct gctcctccca aaagaatgac
     2341 cgccagcaaa aggggaatga gtactttttt cagttttcct gatcccttac tgatctcctg
     2401 atcttcaata ttgatgtgtt tgttttcctg catatcatta tcctccgcta tgattgttct
     2461 gcaaactggc tgtgatacag atcggaatag aatcctttct tttcaagcaa tgtttcgtga
     2521 tttccctgtt caatgatatc gccatccttc ataaccagaa tcatatccgc atcccggatg
     2581 gtggaaagac gatgggcaat gacaaagctg gttctgtttt tcattaattt atccatggct
     2641 ctctggataa agacctcggt ccttgtatca atggaactgg ttgcttcatc aagaatcagg
     2701 attttcgggt ctgccagaat ggttcttgca atggtcagca gctgtttctg cccctgggat
     2761 aagttactgg attcttcatt aatcaccata tgataacctc ccggcagagt tcgtataaat
     2821 tcatcgcaat gagccgcttt tgccgccgct atcacttctt catctgtctt atcaaaattt
     2881 ccgtagcgga tgttatccat taccgtggca ttgtaaagcc aggtatcctg aagcaccatg
     2941 ccgaacatgg cacgtaaatc tcttctggta aatgtaaggc tgtcatggcc gtcaatcaga
     3001 atctgaccgg aattaagctc gtaaaagcgc atgagaagct tgactatggt agtttccagc
     3061 tcctgtggga cctacaatgg caaccgtctg ccctgcctca acattggaag aaaaatgatt
     3121 gataatcatg gtgtccggct gataaccaaa acagacattt ttaaattcca catttccatg
     3181 aacctcagac aatacaatgg ggctttctgt ctcactgact tcatcctctt catctaaaaa
     3241 ctcaaataca cgttctgctg ccgcagctgt tgactgcaga gtattagaaa cgttggcaat
     3301 ctgggagatt ggctgcatga aggatctcat gtactggata aatgcctgaa catcaccgat
     3361 ctcaattacc tttttcactg ttaaatatcc gcctaacaga cagacacaca caaatccaag
     3421 attacccaca aaagacatga tgggcatcat cattcccgat aaaaaactgg gatttccacg
     3481 cagatccata gagtttatcg ttgatcagcc ggaatttctc aatggcttct ttctctccgt
     3541 taaaaatctg gaccacgtta tggcctgcat atatttcttc aatatgacca tttaaatttc
     3601 ccaggctttt ctgctgctgg gaaaaatatt tctgggactt tttcactacg gtaacgatta
     3661 atcccatgga tacaaacaat accaaaactg ccaccagagt cattcgtacg ctgatggaaa
     3721 gcatcatggc tacaataccg attaaggtag tcaccgatgt gatcatctgg gtcagagact
     3781 gatttaatgt ttggcttacc gtatccacat cgttggtaat tcttgaaaga atctctccgt
     3841 gagttctggt atcataataa tttaacggaa ggcggttcat cttttccgat atgttttttc
     3901 tcagctcata ggtgatcttc atactgaccc cctgacataa tgtaactctg cagataggaa
     3961 aagagagccg acacaagata caggacaact aagagcagca gccggtttct gatatagcgg
     4021 aaatctgtaa gcaatccggt tcccatggcc catgccatca gcccttcaaa aagcttggtg
     4081 gttgcctttc ccaatacttt aggtcctaca atggaaaata cagaggaaca gcatgcaaac
     4141 aggattacaa caatgacgga aaccttgtaa tgttttaaat acccggcaag gtggagcatg
     4201 gtacctttaa aattctttgc tttttcagtc ttctggccaa gtccgccgcc ccgacccatg
     4261 ggtccgcctg aggatttttc ttcactcatt tcagttcctc ctcactcagc tgtgacagcg
     4321 cgatttcccg gtatacttca caggttttca tcagctcccg gtgtggccct ttcccggcaa
     4381 ttctgccctg atccagaaca ataatctgat ccgcattcat aatggtactg attcgctgag
     4441 ccactaaaat ggtgacgctg tcttttgttt tatctttcag cgcagctcgc agctttgcat
     4501 ctgtcttaaa atccagagcg gaaaagctgt cgtcaaacac attaaccggt gcccgcttaa
     4561 ccagtgctct tgcaatggaa agacgctgct tctgaccgcc tgatacgttc tggcctccct
     4621 gggcgatttc tgttaaaaaa gccctcgggc ttggaatcga tgaattcctc tgcctgagca
     4681 gttttggccg cttcctccac cacttctttg ctggcctctc tgtcaccata ttttaaattg
     4741 ctctcaattg ttccggaaaa taagattccc ttctggggca caaaaccaat catgtctctc
     4801 agctttttta acggccagtt tctgatatca atgccgtcaa ttaagatttc tccccctgtc
     4861 acatcgtaaa agcggggaag taagttgacc agtgtgcttt ttccgcttcc ggttgctccg
     4921 ataaacgcag ttgtctgacc aggcagtgcc gtaaacgtaa tatcgtgaag aaccgcttca
     4981 tcggcatcag gatactgaaa ggatactccc cggtattcca cagtcccttt gggtgcttca
     5041 gagataactg cagctatctt gggatctgtg atggttgaat ccgtagtcag tatttcgact
     5101 actctcttta tggatacaat ggctcttgga atcataataa acatcattgc catcattaaa
     5161 aaagccataa taatctgcat ggcatactgc atatatgcca tcatgtctcc taccttcatc
     5221 ttaaagctgg atactgcctt tgatcctacc cagacgatta ataagttggt cagattcata
     5281 ataagcatca tcgccggcat cataccggag gtaactctgt taacaaataa atttgtgtct
     5341 gtcagcctgg catttacctt atcaaaccgc ttttcctcaa atctctgggt attaaatgca
     5401 cgaattacca gagttccgtc aaggctttcc ctgactacca ggttcagccg gtcgattaac
     5461 ttctgcacat actgaaacct gggcatcacc accatcatca tggaaaaatc atcacaagca
     5521 gtaatcccac agataaggcg attatccagg acattgattt atccttttcc agggcatgaa
     5581 tgacaccccc cactccaaga atgggtgcat aaaacacgat acggatcagc ataacaatca
     5641 gctgctggat ctgggtaata tcattggtgg ttctggtgat taacgaagaa gtggaatact
     5701 tctccatctc tgcactggaa aaactctcaa ttctggtaaa tacatcctgc cttaaattcc
     5761 ggcagatgcc tgctgccatt ctcgcaccga tcagtcccac gattacggtg cagaacgcgc
     5821 ttaaaaaggc gattcccatc atttgaaatc cggctttgac tatgtacatc gtgtctcccg
     5881 aagtgatacc tttatttacg atatcagaca tataatccgg aagggataaa tcacaggcag
     5941 cctgcccgaa cagcagcagc ataaccactg ctaaagatat caaatggggt ttgaaatatc
     6001 ggaaaaatac cttcaagtca gttccctctt ttctgtttca tcaatctgtc atttcgtcaa
     6061 tttcttccgt catatcattc actgcacgtt ccatctgatc aataaagcgg ttccacaatg
     6121 tgatcagctg atccatatct tccattccca ttccttccac aactcttccc accagcagat
     6181 tcactttctc caggcacttt tttcttacga tatatccctt ttccgtaagc atgacacaaa
     6241 tattccttct gttgtcagga tcaatctccc tggatatcag accccgtttc tccagggaat
     6301 ttaaagtccg tgatgcggaa ggtaatacaa tatccatttt tttagccagt gccgatacat
     6361 aaatgccctt ttgttcctga tctgcgttag ttgcttcata tatctgctga atcgcaaaca
     6421 gttcaagacg ggtcagtcca tgggacagca ggattttatc cacttttctc cctttcccca
     6481 tcatgactgc caagtgggtt tttacctttt ttatgtattt ttctttttca tccaacaaat
     6541 ttttctatcc ccttttaatt acttaatact attaacattt accaacgttc atcattctac
     6601 tcttctccag ttcctgtgtc aataagtatt ttttttcctt tcaaattttt aacaccgaaa
     6661 ggaaaaaaag gtccatgccc tcagagggct gaaccttttt tcagacattc tgttaatttt
     6721 ttacagatgg cagattactt aaattattat tctctgttcc gtcaggaagt gattttaaat
     6781 actcgttacc gtttctggaa gccacaccga caccctttat ctcaccctgt ctggcgagca
     6841 tgacaccttc ttctttattc agtgttctgc cgtcagataa ctggtatccg gttacccggc
     6901 cgctttcttt taccagagca acaatctcct ttgcatctgc cttgggtgat ggaatatcat
     6961 caagagccat catggcaagt tcggctccag cacctttcgt ctgattttct gacattatta
     7021 ttcgcctcct tctaaacatg actgattcgt ttttagtgtt tcaatattct cccggattat
     7081 tcagtattga ttaggcttaa taacctgtaa catactcctc tatccagatc agggaaaatg
     7141 tggtacaatc taagtcaaaa aaaggaggaa atgctttgac ttacatagaa cgaacaaccc
     7201 gttatttttt cctcatgctc ttatataatc tggtgctgct gtctcccatg atgccagaca
     7261 aactgatacg cgttctctcc tgtaccggtt tgatgctttt ttatctttac tgccatatta
     7321 aacctgtgaa taccagctgc aaggagcaaa gacttaaaat tctccatggc ggttatgagc
     7381 ttgtgcttgc gtcaatcgtg acttttctga ttgaaacagc aatttatcta tttctgattt
     7441 ttaagacaac tacaccggca cgccttctta ttatgaatgg aatcatctgt gccattctac
     7501 tttatttact gtttatgaat ggtatcatac ggatctttac ctgttccgga cagcttgggt
     7561 ttttcaaaag gattgcactc ctgctgttct ggtggattcc gggattcaat ctgtttctgc
     7621 ttcacagttt catggaagtt tcgcgtaaag aatatgattt ctcaatggaa aagcaacagt
     7681 tttacgagaa atggaaagaa gaagaattat gtaagaccaa ataccccata ttaatggttc
     7741 acggtatctt tttcagagac tggaaaaact ttaactattg gggaaggatt cctgacgaat
     7801 taatccggca cggtgccacc attttttaca gcaaccatca gtcttccgct tctgtggaac
     7861 aatgtgcaga agaaatcaaa gcctgcattt taaagattgt taaagatacc ggctgtggga
     7921 aggtaaatat catcgcccat tcaaaaggag ggctggacag ccggtatgca gtcagctgtc
     7981 ttggcatgga tgggtatgtc gcctccatca caaccatcaa tacccctcac tacggctgca
     8041 attatgtatg caggattctt gaccgtatct ctcctgaatt tgttaaattc atcgggaaaa
     8101 aatatgaatc cctgtttact cttcttggtg atgacaatcc agacttttta agcggattaa
     8161 gagatttaac tgacagggaa tgtgcccggc tcaatggggt tatgactgat gctcccggtg
     8221 tatactgtca aagtacagga tcacagatgg gttctgcaaa aaagtgccat gtttcctttg
     8281 aatctgggct atctgatcat tcggattctt gggggaggca agaacgacgg tctggtttca
     8341 accagttcca tggtatgggg aaacgattta ggcgttctga aaccaaaagg aaagcaggga
     8401 atctctcatg gagatgtcat tgacttaaca cgcaagaaca tagaaggctt tgatgtgatg
     8461 ggattctata cggatctgat acataagctg aaagaacggg gatattaacg gaaggaatcc
     8521 agaaaggagg agccatgaat aaggatacca ttataaaaag tttaaaaatt gctgtagccg
     8581 ccgtgctctc cattgcaatt gccggggaac tggggcttcg ttattccgct accgcaggaa
     8641 tcattacagt gctcagcatt cagaatacaa aaaaagaaac cataaaaagt gccagaaacc
     8701 ggacactggc ttttgtgtgt gctctcctga tcgcccgttt actttttgga attttaggct
     8761 tcacccttcc tgcatttgcg ggatacttat ttctcttcgc tcttttgtgc ttctatgcgg
     8821 actggggcga agccatagcc atggattccg tactcatcac ccattttctg actgagcggt
     8881 ctatgactgc tgcgctggtc gccaatgagg cagctctctt tctgatcggt acaacagtcg
     8941 ggattttagt gaatctgcac ctgcgaagaa ggaaagatga atttaaaaag ctttctgacg
     9001 aagtggatac ccgcataaaa gacaccttaa gccagatgtc ctgttttctt ggtacggaag
     9061 acaaagacag ctgcagaccg gcggaccttc tgtctctgca aaaggccctc cgcacagcca
     9121 aagcctgtgc cttaacgaat tataacaatg ctctgtttaa aaaaaagata cctacgaaat
     9181 tgattatatt gaaatgcgca ggcagcaaag tctcctgctt tacgaaatct atgaaaatat
     9241 ccggtccatt tcctgtcttc caaaagaagc aatggaagtt tctgagctgt tagcaagaat
     9301 cgagcagggc taccacagag ataactccgt ggaggggctt ttaaaggatt taaatctgct
     9361 actgctggat ttaaaagatc atgagctccc cataagcaga gaagaatttg aagcaagagc
     9421 catactcttt tacatcttaa agcaattgca cagactcctt ttgatcaaac gggaatttat
     9481 cttaaaccac agcagttaat cctagcggtt gtccacccgc tccggataaa gatcatggtt
     9541 cttaagccgc tcccatgcca cctcttccca tctggttccc ggctttccat agttacagta
     9601 gggatcaatg gaaatgccgc ctctgggagt gaattttccc cacacttcaa tatatttggg
     9661 gtgcattaat gcaatcagat ctttcataat gatattcata cagtcctcat ggaaatctcc
     9721 atggtttctg aaactgaata aataaagttt taaggattta ctctccacca tctgttcccc
     9781 tggaacgtag gagatggtta tggaggcgaa atccggctgt ccggtaatag ggcaaaggct
     9841 ggtaaattcc ggacagttga attttacaaa gtaatcgtta ttgggatgct tgtttaaaaa
     9901 ggtctctaaa actcctggat tataatccgt ttcataaaca gttccctgac ttcccaaatg
     9961 ggtcaccccc ttagtttcct ctgaatttct tcctgacatc ttattctcct ctctttaaag
    10021 caggatcttt cattccattc tttgcaaagg catctgcacg atctatgcag gtaccgcatt
    10081 ttccacatgg ttcctctccg ccttcatagc agctccatgt cagttcataa gggacatgaa
    10141 gcatcaatcc ccgctccaca acttctgctt tggtccataa cacaaatggt gcctttatgg
    10201 taagctgatt tccgcttccg atgtagacgg cgcggctcat tgcttcctga aaagaactgc
    10261 tgcagtccgg ataggcattc cctgccgcat catcgctgtg agctccgtaa tagatcacgc
    10321 tgcagccttt tgacagggcg atactggcgg ctgaggaaag aaacaatccg ttgcggaagg
    10381 gaacgtaggt tgataccggt ttgccttcgc tgttttcaag ctgctttgca tagctttctc
    10441 ttggtatctc ttgttgagac tgggttaata aggaacagtc actgtaagca aatattctgc
    10501 ttaaatccag acttataaat tctatctcat aataatctgc aatcttttta gccgcttcca
    10561 gctcttttgc atgcttttgc ccgtaggaaa tagacagacc acagacattc tttcttccat
    10621 attcttcaat tgccatacca aggcaggtgg cgctgtcaac gcccccgctt aataatacca
    10681 gtgctttcat cgttctctcc gtttcttttc tcttatacaa ttttcatatg cgtaattccg
    10741 gctccgactt aaaacgtcct cttaaggtga ctgttttcgt tctggcggaa aaacttttaa
    10801 ttcctcttgc agtcatacaa ctgtggctgc cttcgatcac aacttctata tcctctgatc
    10861 cggtaacttc tgccatgatt tctgctatat ctgaaccaat tctctcctga agctgaagcc
    10921 tcctggcggc catatcggca attctggcaa ttttacttaa tccaatcact ttcccatttg
    10981 gtatataagc cacagcaact ttcatatcgt acatcagcgc catatggtgt tcacagtagc
    11041 tgaacacttc tatgtccttt accaccacca tgtcatctcc tgcaccgttt gtatccatat
    11101 cctcttcaaa ggttttccca aacatcagtg caatttcatg gttagagtaa ttgatccctt
    11161 caaaaaactt ccccgtacat cttcgcaacc ctggacggcg tatcttttaa gccttccctg
    11221 tccgggtcct cgcccaatgc ctttaatatc cccctcacat gggtctgaat tgcatctgta
    11281 tcaatagcca ctctgcacct ctcccttctg attaaacgcc cactgcatcg gatccccaga
    11341 tgattttatg catctgcagc tgaagagtca catcatttaa ctggttctgt ttcataaatt
    11401 ccactacatc aggcaatgaa atactgccaa aaacggtgct aaaataaaga tggcaccggc
    11461 cggaaagctg atagcggtct attacctcca cagcccttct cagatccgtt atacttcctg
    11521 caacaaattt taccgtatcc ttctgtttca aataatcaaa gttagaaagc tgcatagcag
    11581 tttccatttt gcttcccgga agtttataat ccatggtaaa ggtaagtgca tttgtttctc
    11641 tctgataggt tgaaagatct gcacttccgt ttgtttcaac ttccacacga agttcctcgt
    11701 ctaataaaag aagagaaaga agatctccga tgccaggctg gatcagaggt tcccctcccg
    11761 taagagttac attttttata cctgtttctt ttatgtattc ataaatatca agctcactca
    11821 ttgtttttcc gcgtaccagg gcatctttgg cccaggcggt atcgcagtaa gagcaggaaa
    11881 gattgcatcc gtaaaagcgg ataaatacag ccagctgacc tgcatatacc ccctctccgt
    11941 tgatgcttac aaaggtttcc gccacattat aatctgccat ggctatcctc cccgtaagaa
    12001 gcacagtttg caggagtctc atacactttg gcagatttca cttcataacc tctttggctc
    12061 attctttcat aaaagtatct tgaaaattct tctgctgtgg ggcgaaaatt cacttccacc
    12121 agtaaaaatt cctctttttt aagagccgta agggtatcag gctttaacga gcctgtttcc
    12181 atgatcagag aatggtcgaa ataatcggtt tcttctttta aatcctgctt cagcctggag
    12241 aagtcaacga tcatcccctg tgtctgtcct tctttttgaa gtgtagggct ttcaatttca
    12301 attacaaccc gccatctgtg accgtggata tttttgcatt ttccatcata gccctttaaa
    12361 aaatgagcgg agtcaaaact ttgttctgtt tccagataat acattgtctc tttgtccttt
    12421 cgaatttcgg aggcggaatt ttaactttgc cgtaaaattg caaaaaaagc agacatatga
    12481 ctatgcctgc tttctctatc tgcacgaaaa aaaagctata ataactgcaa taacttttcg
    12541 ttccaacaat attaaaatca gccctagttt tgtttataga caggatggta ctaatgaact
    12601 gtcttctatg cggttaaaag tataacaccg tttttactgt gcgtcaagac aagggttctg
    12661 cctgttaccg gatcgcctga ggaaaactga atacatgaag aggatcatac cgactctctg
    12721 tctgtcttaa tctgcagaca ttctcgccgt aatactcctc ttcataatct ggcagccggt
    12781 tataggggaa attgacatag gatccctctg tcattccctt tatatactga aacctgggat
    12841 aaagccactg cctgttaatc tccccatagc aatcattttc ccacacagac tgaatcccca
    12901 tgatataaaa cgcatccctg aaaaaataag cggtgctgac agggcttacc tcccggatct
    12961 taccgccaag tgcatagacg gtaactgccg cataaaccga gccttccgcc cgttctgcta
    13021 tcaggccggc aatctgcatc cgctcttttt ccccgtacat tctttgaaca aatcgtccag
    13081 tggactgaaa cttttcagaa tccggatagg aagattgtat tttttccata gcctgaaaaa
    13141 acgacagttc ctcataagat aaaaccgctc cgtccctttc aaaagggtcc aatatggtcg
    13201 cggcttccct tgcagatcca taaaacaaac ctcttccgaa aatcccaagt ccgtcttgtg
    13261 gtgaattgta catactgata ttcatggtaa ttcggggatc cagacccacc agccatttct
    13321 gccagactcc taaaaatccc gccatttcct caagaccagg tttgatatac tcaagatcca
    13381 ccagagttac tgctgttatc ctgggcggca gcttatactt taaagaggta acaacaccaa
    13441 aattacctcc gccagctcct cttaaagccc agaacagatc tggattacag gtttcatccg
    13501 cagttaagac cttaccttca taattaacta tttccacagc ttttaagctg tcacagccaa
    13561 gccccaggaa acggcttgaa tatccccagc cacctcccag tgtataacca gctgctccta
    13621 cagtaggaca ggttcctccc ggaaagggat atcccttttc tcctgcaaaa ttgtacactt
    13681 cccggttttg aacaccgctt tccatgacaa tacactgccc ggaaccagaa agacggatgt
    13741 ccttcatctg gctcacatca atcaccaata ccccgtttcc ggtggagtaa ccctgataat
    13801 gatgaccgcc tgaccggatt cgtattccca tctcatgccg tcttgcataa tgtactgcat
    13861 tttgtatatc agaaatctgg ctgcaataaa caattacctc cgggaatttc tgaactgccc
    13921 ggttccactc ctgcctggct ttcatattct ttctggcagg gagtaataat tactcccgtt
    13981 aaaccatctt tatataaact cacttttatc accagcattt ctcatagatt cagattcata
    14041 ctgtatgata tgagtttgtc tatcaacagg gcactctggc tgtccggctg attatttccc
    14101 ctctgcttct aactgggcaa tcttttcctg aaactgagga agatgctttt ttgtgagcca
    14161 ctagaagttc atcaaggata gttcccgcaa tcttaccgct tggaaccagt ggatttaagg
    14221 taaatgcctg ctgtgcagtt ccgtaatcac cggttactgc tgcctttatg gtagtcagtt
    14281 ccatgtcctt catcagctgc agcaatcctc tggtggaaga atcaaagctg ccccatgaga
    14341 tgggcaccgg accgcctgct gtaataatgc tgctgacttc cacaaccacg tcatctggca
    14401 gatcggagat tgcgccgttg tttctggtgc tcacaaccat ggtggtctta tcattataaa
    14461 tggatgcgat cagctcacag gcagcatcgg aatagaacgc accgccccgc ttttccagct
    14521 gaaccggctt tatattcaaa tccggatcct tataaagttc aaaaagttct gcttctgtct
    14581 tctttacaag ctctgctctt gtttcccctt ttgcaaacgc ctccagctct tccttcagca
    14641 tatcatccgt aatgtaataa taccggtgat acatacaagg aatgattcca agatctctga
    14701 tctgatctgc taaaaaagcg atattgggaa tattctgaac tccggaactt ttcagcccct
    14761 gcatggcttt tttaaggcca tccggttttg tatatactga ctcaagaact tctcctgttt
    14821 tttctacacc ctcatgattc catactctgt gccagtggaa gtgatttaag ccgccgaaac
    14881 ggaaaaacaa atcctcttcc ttttcctgca aagctcctgc cgcaatcttt ctgcacataa
    14941 tgggaacgtt gcacagaccc actaccttat cccatttgcc gtatcgcatc accgcttcgg
    15001 tcaccatgcc agaggggttt gtaaagttta caagccatgc atccgggcag agttccttca
    15061 tatcctctac aatttccaga atgactggaa ctgtacgaaa cgccttaaac atgccgcctg
    15121 caccgttggt ctcctgcccg attacaccgt gtgacagcgg aatccgttca tccttaatcc
    15181 gtgcatccaa aaggcctacc cgaaactggg tggaaacaaa atctgcatcc tttaaagctg
    15241 ctctccgatc cagagttaaa tgaacctccc agtcaagacc tgctgctttc accatacgtt
    15301 ttgcaaggtt tcctacaatc tccagctttt cttttccctc ttcaatatcc accagccaga
    15361 tttctccgat gggaagttcc tctttccgtt taataaaacc ttctatcagt tcggggtata
    15421 actggacccg cctccaatgg ttactatttt aattttccct ttcatctgct tacctccagg
    15481 tatttgataa aaaaagcata ctccaaaaat cccggaaagg gaacggattt accttctttg
    15541 gtaacaagca agggtgtttt ggcatttgtt ccacaaaaaa aacagggtgt tttatccctg
    15601 tttcttttcc atggtcagcc ttgccagggc ttccacgata taaactgccg gaatctgaga
    15661 agtgatatcc accttcatct cttccagctc ttttctttct ttttgaatat aataggaaat
    15721 gttgtaatct gaaattcttg ccagagtgct gttcctgctg tttgtaatgg ataccagagt
    15781 gctgctgctc tccttcaata tagaagaatt cctctataat aatattggtc tccccttcca
    15841 cagacaaaac aataataata ctttcttccg gaaattccag attaatggga aacatgggac
    15901 cgttaatccc ggttgaaaat attccgatat tgcagaaata ccggcttgca tattcagcca
    15961 tgattcctga attaccagat ccaataaata taatctgccg tttgcctgca atcacttcgg
    16021 cgattgtatc cagctgtttt tgaaacgcat ctgaattgac ccgttcaaaa aaatctgtaa
    16081 tggaggatag atcaaaccgt tttttcacag atcctttctt ttccttttcc agcttaaacc
    16141 gcaccttaaa ttccgaaaaa ccgctgcaca tggttttcct gcaaaaccgg gtgatggtgg
    16201 tggtagacac atgagcttcc ttcgccacct cacggattgt catatacggt atcttctcac
    16261 tgtttcttaa tatataattg taaacctcgt agtccagttc cccaaattgt tccatcacct
    16321 gacgggaaaa caatgtcatt gccagtcacc tcttattaat cctgtttcat ctgtttttct
    16381 gataccaggt aaatatttca tgaatgtcct ccggtgtagt ccggcagcat ccaccaatca
    16441 gacctgcgcc tgcctcatac cactttgctg cccactgtcc gtactgcccc ggctccttca
    16501 ctccatgcca ggtcttacag caggcatcat aagtctctcc gctgtttgga tatgcaacaa
    16561 tgggaaggca tgtatcagta ttataagtca catgccccag attcagcaac ctgttttatg
    16621 ttttcataaa aacttccatt taaaaatgct ttctttgaag catttacctc aaagaaagca
    16681 ttacttaaaa gcttttcaga cctatgcaaa tccgaaatac cgtaaaatac ccagatagat
    16741 tccgtaagca aatccatact ggtcattttc aagcttttct gcatccgatg gattgcttat
    16801 atatcccagt tctactaaat tagcgggcat atctgcattc ctaagtacat ataaagaggg
    16861 attttcacgg attccgttgt ttctggttcc aaccatatca ttaatcccgc ccataatttg
    16921 ttccgccagc cactgtccct gggtaaaata ctgatagatg tatacttccg ttccattaat
    16981 ttcgggatta ggatttaaat tacagtggat gctgataaaa taatttgccg gccactggtt
    17041 tgccattgca accctggcag ccaggctggt agtattgttg gtacccagaa cggtatccgg
    17101 ctgtggtcta gagactctcg cttcaaacct gggatcactg tttaagaggt ctcgaaggta
    17161 aattcccacc tggtaattaa tttctgattc ctgtagtcca ttggcctctg caccgctgtt
    17221 aaaatatccg ctgggattat gcccctgatc aataaatatt ttaattgcca tctcgcattt
    17281 cctttcctgc ttcactatat taaatatatt ctgggaaatg gtaaatgcta catattttgg
    17341 atttttttgt atatttttga atgtattttt atgaataaat aaccttttcc ccatgccttc
    17401 caagccagta tggcaaaccg ggatatttaa tggttatata atcttcaaaa cggtcggggt
    17461 cttcctgatt gctggaaaac atctcataat ggccgggaac cgtaagcccc ggtttcattg
    17521 cccctgctaa atccactgct tcctgatacg tcatgtttcc tatgatattg gaacggtagc
    17581 gtactccatc ccttccgttg atgggaagaa acatcacatc catatcccca aaacttctta
    17641 atttgccgta cagtccttca taaatacagg tatcgcctga atgatacagc ttaacgccca
    17701 ttccttctat cacaactcct gtgtaaggat attgaccggt aaccggatcc tgatccagaa
    17761 actcgtgagc agatgcaatc cctgttattt taataccatc ttttaatatc tggatttttc
    17821 catcgttaag ccccagaaag cggcttttat caatcataag atcctcactg agtacaggga
    17881 tcagcttctc cggcacaaga aacaaggcat ttggcgagct gacggaaagc tgatgccaga
    17941 cgttgcggtc aatgtgatcc aaatgatcat gagttccaat tatgtaatct gcattggtta
    18001 tctcactggg atcaaagagc ggtgcaattc ttctgtcagg acgttcagag agaaatgcat
    18061 cgatatagat tgtaaccgta cccagcttta ctgcataccc cagctgccca agccaccaga
    18121 acgctgcctg tccttcccct ggtactgtct catttatttc tgcaattaag tcttttccgc
    18181 ttttcgcggt ttccatgtac tgctgtttca ttttaaatcc gcctccggtt ccatgttttt
    18241 actttcagat tttatcatac cacagatttt tccagttgca acctgcccat atcagaaaat
    18301 gccgggctgc attaacagcc cggcagtact atgtgcatgc ttaagataaa tttctggctt
    18361 ctgcaaaaac cttcgtcagc atatttataa ctttgctata ttaattgttc tgaaatacct
    18421 cttctcatat tttatcctat gtaccatagc ttttccccgt gatgaaaaaa atgttttttc
    18481 cgtatctttt cccttttttt tcttattaca taaggcagtt ttgacgacat tctaatcaga
    18541 aatattaaaa ggagaaaaca tatgataacc tacaaaaatc tttatgacaa tggaaacatg
    18601 cttaagatta atgaacgtgg ctgtgttaag gtatttgagc atcagaaaga tttaagtgtt
    18661 gaagccggct ctgccatcgc ttcctattat gcttccaaga tgaatatccg aaaaaggcag
    18721 gttttaattg aactaaacgg caattccttc accgttcagg ctggtgccat gcagtggact
    18781 tccggctccg tatccatgac ttccggaata aagggcgtag gcgattttct gggtaaggca
    18841 cttgcttcaa aggtaacaaa agaatcttct gcaaagccgg aatttaaagg cagcggtctt
    18901 ttgatgctgg agcccactta caagcatatt cttctggagg aggtttccga atggggaagt
    18961 atggtgctgg aagacggatt attcctggcc tgtgattccg acatcaaaca gaatgtagtt
    19021 gcaagaacca cactgacttc agcagttgcc ggtaaggaag ggttctttaa cctatgcctg
    19081 accggacagg gaattgctgt tttagaaagc ccggtaccca gagaagagct gattgaattt
    19141 gaattaaaag acgatgaaat taaaattgac ggaaacatgg caattgcctg gtctaattcc
    19201 ttaaaattca cggtagaacg ttcctccaaa tccctgattg gttccgcagt atcaggggaa
    19261 ggccttgtca atgtttaccg gggaaccggc aagattctca tggcgccagt gggttaacaa
    19321 cttcattatt tattaacccc aaaccggata tgtcacataa ccaatgacat atccggtttt
    19381 tgattataaa tatctaaata aattttaaaa caattacgga aataatgtct cactatttct
    19441 taataattct taaatcaggc tatatcgcct tgttattgca tctataagtg atataattca
    19501 cttgattaaa tcaatcaagg aggcatctgt ccatgagttc catacagcag atattggtgg
    19561 tagatgacga cgcggatatc cgggaagtga tccgtataca gctggagaac aaaggctatc
    19621 tcgttttaga ggccgctaac ggcagcgacg cggtaaatac agttagagaa aatcctgata
    19681 tcgacctgat tatactggat atcatgatgc caggtatgtc cgggattgag gcatgtgcac
    19741 aaattagaac ctttcattcc gcaccggtat tatttttaac tgcaaaatca aaagagacag
    19801 ataaaaacga tgcttacgaa aacggcggcg atgattatct ggtgaaacca ttttcccagg
    19861 cagaactttt tatgaaaatt cagtctctct taagaagata cgttgtctac aaagggaaat
    19921 cggaatcttc cgtaaatctt tcggaagtcc atgttcagga cattgtgatt gatacggtaa
    19981 accactgggt ataccgggaa aatcagaaaa tagagctgac cgatacggaa tatctggttt
    20041 tgatgtatct ggtcaaaaac aaaggtactg caaaagatgc tcaggccatc tatgaggggg
    20101 tatggaatga aaagtttctt ccttcctcca ccaataccat tatggttcat attttaaagc
    20161 tgagaaagaa actggaactg gattttaata atccgttaat tatccgcacc gtctggggaa
    20221 agggatatca gattgatgaa gggtaaaaca ttatcctcac tgcgttataa gcagatactt
    20281 gtacttctgt tcggagcatt tttaagcttc gccgtatatc tgattgttgg aagcctgggt
    20341 gattacatgg tttcaaagaa acacatggat gaagactcgg tacagtatcg gttaaactcc
    20401 tatcagaatt cttttgaaaa ctatgtgaaa aaaaataaaa tatcggtaaa aaatgtaaga
    20461 gccatctcca gatgggtcaa gaatcataaa tatgtatatc tgaccatata taacggggat
    20521 gaaattcttt atgaatccgg ttactggaat gattcttatt cttcctatga aactgccaca
    20581 acaattgtgg aaagctgcaa tcagaaggaa cgtgatattg tcttttcaga cggcacctac
    20641 tccgtatcca tcatcgattc ttctcagatt aaatggctgg atgtagtgct ttactgttcc
    20701 tggattatgt tttttattgt attttttatt attattatcc tttataaccg acggatcatt
    20761 caccggattg ttcttctgtc aaaagaagta tctttaattg aacagggtaa tttggaacag
    20821 ccgatttttc ataaaggaaa tgatgaaatt tcacttctgg ctaaaaacgc agataatatg
    20881 cgtaattcca ttatcacaag atacaaaagt gaaaaggatg cctgggaagc aaacagcgag
    20941 ctgattacct ccatgtccca cgatatccgc acacctttaa cttctttaat cggatatctt
    21001 gagattttag attccaaaga ttaccattct gaagaacagc tggagaaata cattaaaaac
    21061 tgtaaggaaa aatcaattca gctgaaagat ttatctgata aactgtttca gtacttcctg
    21121 gtatttggta aggataccat ccttatgaat atggaaacct ttgatgcgag aattctgctt
    21181 caacagctgt taagcgagca tgtatttaac ttaaacagcc ttgggtttga agtacagact
    21241 gaatttatga atgaaccctg caccatttta attgacattc agtatttaaa acgtctcttt
    21301 gataacctgt tttccaatgt gagaaaatat gctggtcacg gcactcctgt tgtagtaaaa
    21361 ggtgccagag acggtgataa tttaataatc agcattacca atgaaatccg gactgacctg
    21421 gtttttcagg aaagcactaa tataggattg aaaacatgcg gaaaaatcgc cgagcagatg
    21481 gacgggagtt ttgaaatcct cactacggaa tcacttttta cagcctgcgc cacttttccc
    21541 ataaaaccgg caggaaagga aacacaatca tgaataatat tttagaatat ctggaacatt
    21601 ctgcaaaaga atttcctcaa aaaaaggcag ttattgatcc ggaaaccagc tgtacctatg
    21661 aagaactata cgaccgggca agacgaatcg gcagtttttt atccgagcat actaaaacag
    21721 gaaaacctgt tgtggtcttt atggataagt gcgtggaagc ggtgacctct tttatgggaa
    21781 tcgtctatgc cggctgtttt tatactttca taagtcccga tcagccagtt gcacgtatcg
    21841 gccagattct tgatgtacta aaagcagact gcatgatcac tcttttaaag acagacgaaa
    21901 aactgaaaca gctttcattt aaaggcacta ttttggaata ccataaactt atttcttccc
    21961 ccgctgatcc ggaaagatta aaagctgtca gggagaaatc actggatact cagcctttgt
    22021 attgtaattt tacttccgga tctaccggag ttcctaaggg agttttagta agccaccggt
    22081 ctgtgattga ttttatggaa tattttcctg atctgtttgg gattacagga gatgatatac
    22141 ttggcaatca ggcgccgctg gactttgatg tatcggtaaa agacctctat tctgccttta
    22201 aaaccggcgc ttccattgtt ctgataccaa aaaaatattt ttcgattccc accatgcttt
    22261 tggattgcct gtgcgagtat cagattacaa cactgatctg ggctgtttca gctctttgta
    22321 tggtgactca gttaaaaggc ttcacatata aagtgcctga acatgtaaat aaggttttat
    22381 tcagcggtga ggcaatgccg gcaagccacc tggctatctg gcaaaagaac cttccaaatg
    22441 ccagattcgt aaatctttac ggacctaccg aaattacctg taactgtacg tattatcctg
    22501 ttttaagagt atttgaaccg gaagagaaaa tacccattgg gacgtcattt cccaatgaac
    22561 atgtatttct cctgggatcg gatgatgaac ttattacatc tgaaggggaa attggagaaa
    22621 tctgcgtggc aggaaccgct cttgccctgg gttattataa caatccggag cagacaaaaa
    22681 aagcattcgt tcagaatcct ttgaatgatc tctatcctga gaccatttac cggactggag
    22741 atcttgcttt ttataatagt cacggcgaac tttgtttctc cggacgtaag gattttcaga
    22801 ttaagcacat gggacaccgg attgaactgg aggaaattga actgatttta aacagctatc
    22861 cggaaatcag ccgcgcctgc tgtgcatttg acagcgaaaa aaccgccttg ctgcatttta
    22921 ctgcggggat ttagataaaa aggaattgct aaaacgtatg cgggaaacac tcccttccta
    22981 tatgattccc agcctgtgca ttcccgtact tcacatcccc gttactgcaa acggtaagat
    23041 ggacagaaaa aaattattgg agatgtgttt atgaaatcag aagtaaacga atcaaaactc
    23101 aagactgcac ttgcaaatta taaaacacca ttttatcttt ttgacacaga cattcttgca
    23161 aacagaatag cggacatacg atcagcactt ccgcccaaaa cccagatttg ctttgccatg
    23221 aaggcgaatc cctttttagt gaaggacatg gagatgcatg tggattattt tgaagtttgc
    23281 tctcccggag aatttcatat ttgtgaacgg gccggcattg atgaaaaacg gattgtgatg
    23341 tcaggcgtat ataagaaaca ggaggatatg gagtatgcca tatccagata taaagatatt
    23401 atctttaccg tggagtccat ggaacactgg aagattctta cctcctgtgc gctgaaagaa
    23461 aaacgaaaca tccgggtact tttacgcctc accagcggaa atcagtttgg aatggatgag
    23521 tcatccatcc gccggattat catggaaaaa ccctgtgagt atgtggagat cttaggtctt
    23581 cagtattttt caggaaccca gaaaaaatca ggtgcgaagc ttgaaagtga attgatgatg
    23641 ctggaccagc tttgtgtaga tttaaagaat cagtatcagt ttacagtaaa aaaactggaa
    23701 tacggtcccg gccttccggt ttgctacttt gaaggggaaa aaagatgagg aagaagccat
    23761 gcttcttgca ttgtcacaag ccattgagca tctgtccttt caaggtcagg tcacactgga
    23821 aatggggcgt ttcattgccg catcctgcgg agtttacgca accagcgtag tagacttaaa
    23881 aaccaacaat gaccagtctt actgcatcgt tgacggaggt attcatcaac tgaactatta
    23941 cggacagatg ctggctatga aaaaaccttt tatcaaacat tacggcagcc agaatggcga
    24001 agtcagggaa tggaccgtct gtggttctct ctgcacttcc agtgatgtgc tggtaaggca
    24061 gtacccgttt aaagacttaa atcagggtga ccaccttgtt tttggaaaaa caggtgctta
    24121 ctccgctaca gaaggaatgt ccatgttctt aagccgggat cttcctttgg tacttcttta
    24181 ttcagaacat gagcaatacc ggattgcaag agcttctctt gcaaccgacc agtttaattt
    24241 ttttcattca gaaaggggat aaacatatga acagattatt agagatttta aacgagatta
    24301 acccggggat tgattatgag acagagacaa gactgatcga cgacgctctt ttggattcct
    24361 tttccattct ctcactgatt cctgagcttg aggatgcatt tgaggtttcc attactccgg
    24421 ctgacatgat acctgttaac tttaattcag caaatgcgat ttggaccatg attaaccggc
    24481 tgaaagagga ttaatctatg acctatactt ctatccttta cctgttcatc tttcttcccg
    24541 gtgtcatgct gctttaccag ctggcaccgg gacgccaccg gtataaagtt ctactggcgg
    24601 ccagctggct gtttttcttt ccctcagcgg aaaattaatt atttatctcc tgatctccac
    24661 tgtttccgtt catcatatcg gtctgtggct ttcttcctgt aaaaaggatc tgaatttaac
    24721 aggagtttct tcggaagaga aaaaatctct gaaagcagcc tgtgccgtca aacggcggag
    24781 aatcttgtgg ctgggtttgg gaattcagct tggcatgctg gtagtactga aatattccgg
    24841 atttttcagt gataatatca accatctgtt aaaggcagtc tcttatccga acctgctgcc
    24901 tgccatgaaa tttgctctac ctataggaat atccttctat accttacagg ctgtttccta
    24961 tctggcagat gtatattatg aaaaaattcc ggctgacgac catctgggca gactggctct
    25021 ttatctgacc ttctttccca tattaatgga aggtcctgta tgccgctatt cccagacagc
    25081 caatgcgctg actgagggaa aacctctgga atacaaaaat gtaacctacg gctttcagag
    25141 aattctatgg gggctgttta aaaaactgat cattgcagac cggctgaatc tgcttgtgga
    25201 gacggtcttt ggatcttata atcaatacgg gggcattgtg gtaattctcg gtgccatcct
    25261 ctatacattt cagctttacg cagatttttc cggctgcatc gacatgacca tcggaaccgg
    25321 ggaaatcttt ggaattacaa ttcctgagaa tttcaggcag ccattttttt ccaaaagccc
    25381 ttccgaattc tggagacgct ggcatattac acttggtacc tggctgaaag actatgtctt
    25441 ttatcctatc tccttaaccg ccccggtgaa gaaattcgga aaaaattcca gggcaaaatt
    25501 aggaaagcat gtggggcagg tagttgcttc cgctccggca cttttttggt gtatggctct
    25561 ccaatggttt ctggcatggc acaggctggc attatctgtt tttcggtatg tattactttg
    25621 tcctgatctt actggagaac ttaacggaac cttttgtaat aaaagcagct gagcacttaa
    25681 agattaaccg gaacaatgtg ctataccgca tcttccagtc tgttaagctt ttaatcttcg
    25741 ttttcatcgg tgagttgttt ttccgggcgg aaaccatgac agctggttta tccatgttcc
    25801 agtctatatt tacaggcttt gatacaaagg tactgaccga cggctcactg ttgcagcttg
    25861 ggctttcttt agctgattat acagccgtat ttttaggctt tctggcagta ctgacagttg
    25921 gtatcattca cgaacgggga atctccataa gagataaaat atcaggatat aagattccgg
    25981 tacggtggac tctgtattat ggtgcgattc tacttgtaat cgtcctcggt gcatacggcg
    26041 acggatattt accggcaaaa atgatctatg ccggatttta agaggtgacg gaatgcatgc
    26101 aggaaacaaa ataagaactt tagcctttat taccggactt acgcttcttt tatatatcat
    26161 gtcctttctg ttccttccag caaacaccgg agcagaagga ctttataaaa aagccggagg
    26221 aatctataaa gaacccaaaa ataccatcgg atacttatcc atcggagaca gtgaaagttc
    26281 caccagcatc tctcctttgg agatctggaa tacttacggg tatactggct ttaacttagg
    26341 cgtacccgca cagagactac aggataccta ttatcttctg gaaaaggtgt taagtaaaca
    26401 gtctccaaag gttgtgctgt tggaaaccaa tgcctgtttt cgagatttta aatacatcaa
    26461 tgccctggaa acaattattg atgataaaac gaaaaagata tttcccattt accagtatca
    26521 taacaactgg agatatttcc atttctatat gttgaaaaat ttaagcgctg atatggcaga
    26581 aaaaccatct cctgcatata agggctatca atataatatt aacagcaaac cttatatcgg
    26641 aggcccttac acagaagaga cggatgagat tgaggtaata caggatcagc cctatctgta
    26701 tctgacaaaa atcagcgagt tatgtaagga aaaaggaatc cggctggtct tatacagctc
    26761 tccttctcca aaatgctgga cttatgcaaa acataatgca gtaaaacagt ttgccgataa
    26821 aaatgacctt gattacatcg attttaacct gtctttagac cagttatcca ttgactggaa
    26881 cacggatacc agagacggcg gagatcatat caactattac ggagcaaaaa aagtttctga
    26941 ctatatggga agttacttat ccggtttaaa cctcctgacc gatcaccgcc aggatccccg
    27001 gtttgtgtcc tggaataatg aatttaaaac ctatgagaca cagaccatga gaagttctaa
    27061 gtaaaaactg gtcctgcatg caagaatgct gcaggacctt tttctattcc tattcctgtc
    27121 tgtagtaagt aagaaaatcc tttagtctgc tgcatgcaga ttttaactgt tccatctccg
    27181 gcagataaac caccctgaaa tgatctggct tctcccagtg gaaaccaccg ccgtgagtaa
    27241 gaagaatctt tttatctctt aagaaatcca gaacaaactt ttcatcatca taaattccaa
    27301 atcgttttat atcaatctta ggaaatacat aaaaagccgc ctttggtttc gttgctgaaa
    27361 ttccaggaat ctggtttaat gcctcatata tgtattctct ctgctcgtaa atacgaccgc
    27421 ctggaaccag aagcttcttt gtctcctctt ccatctcaag agctgtctct atgacagact
    27481 gggcgggaac attggaacac agtctcatgg aagacaatag attgattccc tccacatatc
    27541 cccttgccga ggatttgtcc ccgcaaaggc tcatccagcc gcagcggtat cctgcaatta
    27601 aatgggactt ggacagaccg ttaaacgtaa tcgtaaggag atcaggagca agtgaagcaa
    27661 tggatgtatg gaccagaccg tcaagaacca gtctgtcata gatctcatca gcaaaattat
    27721 gagaccattt tcccggcaga gcttaacgat ttcttccagc agttctttgg aataaagagt
    27781 tcccgtggga ttattgggat taattacaac gattcccttt gtgcgttctg tgatcttgct
    27841 tttaatatca ttgatatccg gataccagtc tgcagcttca tcgcagatgt aatgaactgc
    27901 agtacctcct gccagcgtta cagatgcggt ccacaggggg taatctggtg aaggaaccag
    27961 gatttcatca cctgagtcca aaagaccctg catggaaagt gtaattaatt cactgacccc
    28021 atttcctgta taaacatcat ctgttcccac ttcctcaatc ccttttttcc ggcaatactt
    28081 tacaattgct tctctggcag agagtaaccc tcttgaatcg gagtagccct ctgtatggac
    28141 cagattactg ttcattttca tcagaagctc ttccggcgca cgaaagccaa atggagcagg
    28201 atttcctata ttcagcttta agatctcgac tccctgggcg atcattcggt ttgcttcgtc
    28261 cataaccggt cccctgatgt cgtaacacac ataatccagt ttttttgatt tttcaaattt
    28321 tctcatgata atttccctct ttcctgattt ttgcataaaa aaaggcccca agcgttcata
    28381 cgcttagggc gaatatacaa tccgtgttac cacctaaatt cagagaatcc tctgcactcc
    28441 atacggtact gacataccgc gtccctgtaa cgtgggaatt ccgttgaagc ctactaggga
    28501 aatcctcccg ttgggttcaa agctccgaga ctgcttccat atacttcaat aaaggttcac
    28561 accagccacc ttctctctga aattctccgt atacgtacta ttcctcttca ttgccttttc
    28621 actatttccg aaactataac acaacaaaat tcagttgtca atactatttg caataactga
    28681 tgcatttatc aatccaggct ataatattct cctgccgcat aattgcgccc tgaagcacaa
    28741 gaaaatcccc gaacctgtct gattcgcgag gcggaacttc ggtatagggt tcatttttct
    28801 tttttaatgt atttaatcgt ttcacatgct ggattcgctg actctccaaa agtcggagtc
    28861 ttgtttccac attcatatta cctgaaaaat acatccggag acgaaatata tctttgggag
    28921 tcttttgcat cttttcatcc ttattcagcc actttgcaaa gtcctcatag ccatcttccg
    28981 ttatggtata acgttttgct tccaggattt ctccgcttat ttcaatgtca tagctgacaa
    29041 gtccctcgtc atttaacttt ttcagttccg gataaatctg gctatgattg gcataccaga
    29101 attctgccag ctcactatta aattcttttg ctatttcata accagtcata gggtggcggc
    29161 ataaaagccc taatatggca tatttcaaac ttctcatttc attttccccg attttcttaa
    29221 tttcttgtta taactatagc aaaaatggaa aatatgtcaa tataacagta ttgtataaaa
    29281 tattagaatt atatacatgt ttatattgac atgtttcatt gatcatgata taaacattgt
    29341 tataataata acaattagga ggagtagcat gaactacaac aagaaaagat ggttgattct
    29401 catcgccagc tgtctcatta acctatgcat cggttcctta tatgcatgga gcgttctttc
    29461 cgtaccaatg gcagagcatt taagtcagat cacaggaatg aaactgactg ccagagattt
    29521 atccattgta ttcgtaattg ccaatgcagt aggtcctatt accatgatta ccggaggtac
    29581 cattaacgac acactctggg cccgaaatta gcagtcttaa tcggaggtat catgtttggc
    29641 ggcggtatgt tcctgtccgg ttatgccaac agcgttaatt ttttaatcgg aacatacagt
    29701 attttactgg ggttaggcct tggaatggtt tacggcgcca ccatcagtac atccattaag
    29761 tttttcccag acaagagagg tcttgtagga ggacttacca cagcgacgtt tggaatcagt
    29821 tctgttatta ttccacccat tgctgccatg atcatatcaa caacaggtgt tacttctgca
    29881 tttaaaatta ttggtgctgt ttttacagtg attatctgtc tgggcgcttt ctttatggaa
    29941 aaatgccctg ctgatttcgt tccggaagga tatacacctc cttctgccgg caaacaggct
    30001 gccatgaata aaaactggaa agagatgtta caaacaccgg ttttctacgt tatgattgta
    30061 ctgcttacct gcggcgcatt tgctgccctg atgtttattc ccaatggctt cccctctggc
    30121 tcagaacatc gtgggaatgt ctgttgtttc agcaacagct gccgtttcta ccctggcatt
    30181 atttaatgtc cttggcagaa tcctggctgg atctatctcc gacaaaatcg gacgaatcaa
    30241 caccctggca cttgcctgtg taatgtctgt catcggtctg atcctgcttt atttctgtga
    30301 caagggtgat gtggttttat tctatattgc catctctgtc attggaatct gtttcggtgc
    30361 tttcatgggt gttttcccag gctttactgc ggatcagttc ggaccgaaaa acaacagtgt
    30421 caattacgga atcatgttta tcggattcgc tctggctggt accgtaggac ctattatttt
    30481 aaacaagatc tttgctgcta ccggaagcta taaaaatgca ttcctgacag ccatggtcat
    30541 ctctttagcc ggacttggac tcacattcgt ctatagaagc attcataaat caaaagcagc
    30601 ataaattggg gaatataaaa taaaaagacg cgtcttcacc aggcaactga acggaacctg
    30661 gcagacgcgt tttttatact cataattact gcacttcttg tccatctgcc ggaaatacaa
    30721 ttccggccat tctccttgcc tgagtcagaa tttcgcatac gcaaagagta tgatccagat
    30781 agcggtaaca ggtggcaaga tcaccggaaa gaatcatttt ttcaaactcc agaaactcac
    30841 tgatcattcg atgactgtag gaatgatccg ctactgtctc ttccgatccg tcatttaaaa
    30901 tcacacggcc cccctcacag atattcgccg gactgtcctg tatcagatac cctttgtccc
    30961 cctgaataat acaggaattt ggtgcactgc agtccttggc tccggtcagg gtgcaaagaa
    31021 agcttccgta atccagtaaa agcactccgg aggtgtcaat tcccctttct atatttgcaa
    31081 aataatgaac cgattcaggc attccaaaaa ggcccgcagc gtaatggagg ttataaatat
    31141 taatatccat caaggcacct ccggcgcatg caggatcaaa ggcaggaagc acttcaccat
    31201 ttttaaaacg gtcataccgc ctggaatact gggaatagct gcaccggacc agtctgacgc
    31261 ttccaagaga aggaatcagc tcctttactc tcctgtaatc cggctggtat aaagtggtaa
    31321 cagcctcaaa caaaaataag tgtctctctc tggctgtccg gcttaaaacc gtggcctgct
    31381 ctatggtagg agtaaatggc ttttccacta ttacattctt tcctgccagc aatgcctgat
    31441 atgcatagga aaaatgaaga tgattgggta atcccaaata taccgtatcc gcttcgctct
    31501 ttaaaaaatc ttcataatcc gtaaaaacct gcccgattaa atattccttt gcaagggctc
    31561 ttgcatcctc ttcgcttctt tttgtactgc agagagataa aattgtggta tgcttcagat
    31621 gatgggcaat ggataaaaaa tcttttacaa taattccaga accgacaatt ccaagcttca
    31681 taggcccttc tcctcaactt tacttaactc acctgtaaca gaatcaatca caagtccata
    31741 gacccggatc tcttccggaa ccaatgggtg atttcggatc agttccactg atttattgat
    31801 ggattggtct aagtctttaa atccacccag ccaggattca aaatcaattc cataatactt
    31861 aattaaatcg atatccttct gtctgattcc ccgtcccttc atcagctcta tcaacttgct
    31921 gctgtctgta tatctggctc cgcagtccgt gtggcctatt accagaattt ccctgacatc
    31981 cagctcatag atcccaatta gaagacttct catcacgctg ccaaaaggat gggaaataac
    32041 ccctcctgcg tttttaatga tctttgcatc tccattttta aaacccagtg cagccggaag
    32101 cagctctgtc agccttgtat ccatacagga cacaattgcg gttttctttt ccggatattt
    32161 attggtgata tatttttcat aatttttatt tttaacaaat tctttgttgt attccagtat
    32221 ctcttctaac atattttgtc cttctcctta catgagtcat tcatcattgg tacgaaatac
    32281 tctccagatc actcctgttc caggaacaaa gatattgggg tccccttcga tatttagacc
    32341 catatctacg atatacatgg attcattggg accaaacatc agatgactcg gacgctcaag
    32401 tcctcctccc ttggaaaggg acgcaggaaa tccactcata ttgatggcaa atgtactgat
    32461 ggttcttgcc ctcaaatcaa ttttggatat ccggtgcccg gcaccagcat aggataatcc
    32521 gtcaccaact gctgttctaa tggtgctgcc atattccgcc acataaacat ctccgtatgc
    32581 tccaaatttt tgattgtaat taaaatcaaa actcatcaaa gtggaattgg gcggaaaggt
    32641 tacatagggt cttggaggaa tgtttggctg atttttcaac agcagagtgg gctgataacc
    32701 acctgtgggc gtgaatcttg gagaatttac cggttctcct cctgaataat caggccagcc
    32761 ataccagaga tccggggtta tgtaatagaa atcatcggtt gcattctcta tgggtctgct
    32821 accaaccgga ttaaacccgt tattcacagc atacaactga ccgctgttat taaactttag
    32881 aaagatggga ttacgaaacc cccaggctac ctgttccaaa ttagaaccgt caaggttggc
    32941 ccgtaagata ctcccagacg ccttggtata tttttttctt atttcaaact caatattagg
    33001 aatcccatag ggagaaaagg caccagtata ggcaggatca tcagtaactg cttccgtaag
    33061 aatattatct gttgtaaaat tctgaccagt cagtatgaca taatctcccg tataatcaca
    33121 tagcaatgga gaaaccggta cccaatcgtt atcatttcca acaacaccgc tgttggtaac
    33181 ggttccctgc ccaaaataga tcttatagtc cggtgaaaag gcaaccggac cattgtaatg
    33241 atcaccgttg cttggcagac ccataataat attctgtctt tgcccatccc ggaatattct
    33301 ggtgacaaaa cctctgtggg atacataaag aaccccattt aaataattaa ttccggaaat
    33361 aggggtaaca aaatcttccg ctatcagttc aagctctcca ttcaccagtt tcaaaacctg
    33421 gggattgcct gtggacaggc cggagtcagc aatataaaga cttccttcct catcaaaaac
    33481 aatgcctgcc ggtgaattga gattttctaa aaacacttct atcccatacc cttttacaat
    33541 ataaatatca gcagggttta aataacgcct gggagcagga tcgccgtcgt tacaagagtg
    33601 aatcctgctg ccgttattct cacgaaacat tcacttcacc tggtattttt tactattata
    33661 ttcactgcac cggaaaatat caatcctgtt tggctgcatc tgcatggagt aatggcagat
    33721 atgcttcgta cccttccgtt ttcatctgct ctttgggaat aaatcttaaa gctgcactgt
    33781 tgatgcaata gcgcagtcca cccatctcct gcggaccatc tgtgaaaaca tgaccaagat
    33841 gggcatcccc taatgtgctt cgcacttctg tgcggtgtct gccaagagtg ttatcatcaa
    33901 gttcctgcag cagatcctgt gtcagcggtc tggaaaagct tggccagcca cagccggatt
    33961 caaatttatc acaggataag aaaagaggct ctccggttgt cacatccaca tagattccct
    34021 ctctctgaat tcatcaaaat attcattctg aaaaggagct tctgttgcat tgttctgagt
    34081 cacctgatac tggattgttg ttagttcatt tttaagttca tcctgggatt ttggcgggaa
    34141 ttttttgctt ttatccactg cctgctttgc cttttcaaat ttatccccgg atatatggca
    34201 gtagccctgg ggattcttat tcagatactt ctggtggtac tcttctgctt tgtaatagtt
    34261 ggtaagaggc agacgctcga ttgcaatctt ctctttgtaa ttcttttgaa gttcttccac
    34321 tgatttttca attaccggct tatccccttc gtcagtgtaa taaatgcctg ttctgtactg
    34381 tgtaccggta tcaccgccct gacggtttac actgactgga ttgataacat cgtaataaag
    34441 tttaagaatg tagggaagcc ctatgacagt atcctcgtat tccactttca cggtttccgc
    34501 atgaccagta ttgttataac atacctcctc gtaagtggga tttttcgttg ttccgttggc
    34561 gtaacccact tctgtattta aaatcccagg aatattttcc aaatattttt ctgttcccca
    34621 aaagcagccg cctgctaaat agatctcttt tttcatggta tcacctttct tctttcatag
    34681 aatcaaataa atgatattgc ttcatcagtt ccagacccga ctggagaatc tgcgccgtca
    34741 tccccccaga tcacccagtt ctcataccgg taaaacaaaa tatcccgggt tcctttcgtc
    34801 catgaatact gattgcctcc tggaatccat tcatagggaa aatcttcagg agtctccgta
    34861 atcagcatgc tttcgtatgt ttccggtgtt atgcttttta aataatcaag aggcaccttt
    34921 atgatttctt ccacttcatc ggtactgaag gtatcctgat aatctcttag ttcaccgata
    34981 aaggagtgaa taatcagccg gaagggagaa atatagatat ctccaggtcc aagcacttta
    35041 atctgcccgg atgtgacgtt taactcttcc atggtttccc tgactgcaca ttttttcagt
    35101 gtctcccccg gctccagctt ccctcctgga aagcaaatct ccccgggctg atgctttaag
    35161 ttactggacc gtttttcaaa cagaagatac tttgctccat caattgtcag aacgggtatt
    35221 aaaaccgcat acttcctgta cttttcttct tcaaccattc cgggttttct gcgggaaaat
    35281 gtctgcctgt ccaaaacgcc acctcctttt tgctatgagc aattatagca tctttttttg
    35341 cgtctcacaa tatgaggaat ggatatggac gaatagttct tatccaatta gcatagaatg
    35401 cagtaattta aaaattatgg agcaaccctt atgacctcga aagaatccta tatacaatgc
    35461 tcactccagt accatctttt ctggatccgc atattaaaag agcacgccat ctttattgag
    35521 gctactatgc ccccgcctgg aaaagaatat gcagatcagg cagatacata caaacagcaa
    35581 tacgaccagc tgttagaagt agccattaag ctgtcaaacg gagtcatccc cttaagtgtt
    35641 cttgaatccg gccagtttta tacccagtat acggaagaag cagagagact tgcacagctt
    35701 aacaccggaa ttacaatcaa ttcccagctg acccgcatgg cttatgacat tgtaccctgc
    35761 accgctgact ataccgcaac caacaaaaat gaacaggatg tattcatgtt gaaccagaat
    35821 cttttaaacc tgaccacttc cttcgtccag tttcaggcag atctcttaaa caaacgtgta
    35881 tcctgcggtc ttttcaccat gatgtataca ggcgatatct tacatattct catggaagcc
    35941 aaacgttacc ttgaaattct gaaacggctt cagagccggg atgattcact cctgtctgat
    36001 tataaatctt tctggtcgca caatatggct gatcatgcaa aggtaatgcg cggacagtta
    36061 gatcccacgg aaacttcata ttttaacgct gccaatcagt ttgccaatac ctttgatcag
    36121 ctcagcacag ccgaaatgaa tccggatacc ttcccttctg accgggaaat tctttccgat
    36181 gccattgcga tcagtgattt taaatcagat accacgaacg gactgattac ctgcaagatt
    36241 caggcaatca tgcttgcact ttataccgat caccttctga gggaggcaaa tcattttatc
    36301 tatcttatgt atgcaggaag ctgagtaaaa tcataaaaat gcgccttggt ctaaggcgca
    36361 tttttatggt tcttcaggct ttctttgccg atggaaaata tttctctgca attttttgtg
    36421 cagtccttac cgcaagagcc tgggtggtaa gggtgggatt tggaccgccc agtccgttgc
    36481 ataaaacact gttatctgct ataaacagcc tctttacctg gaatgcttcg caaatcgtat
    36541 ctgtaacaaa tccaatcctc atggtgctca taatatgagc acacacatcc ggcggccagt
    36601 tagcccggct gacggtcttc gctcctgctt tctttaacac ttccgccgca agtcccacaa
    36661 gctgatctct tctctctctg tcagcatcac tgatctcata gctgatcacc ggtatatagc
    36721 cattttcatc cctgcgctcc ggatccagtg tcaccccgtt tttctgactt acatcgtcgt
    36781 cggaaaacac tacaatactg agagtcttgt tgtaatttct cataaattct tttaatagtt
    36841 ctcctgcaat aatgccttct ctgtcccagg cttcttcttc cctggtctga ttctggaaat
    36901 agtacccctt ctgacttgtt ccatatatca tggttgaatt gataccggga ctggttccaa
    36961 agggttcaaa cgctccaagt ccgggataat ccatcctggc agccgaattc tgacctacat
    37021 aaggctttac ttcagacatt cccagaatat tcatcagatc ctcttcttcg aaaattccgg
    37081 atacacagtc aatcatatga gtggtcaatc cttttcctac ccattcattt tcaggaagtc
    37141 cggaatttag ccatagtcgg ggagattcaa tggagccggc agacaaaaca atcactttgg
    37201 ccttaaactc cctgatttct ccagtccatg tgtttcggac cgttacgctg ctggcaaaca
    37261 aaccctcttc ttcattttgg ccggtatgga tagcagtcac aaaagaattt ggcataatgt
    37321 caacatttcc tgtcgccaaa gcatagggga tatagctgac cagggtggaa cgctttgcca
    37381 cacttcccac attgggtcca atacagcagc cgtttacaca gtgaccgcga agagtacagc
    37441 ccaccgcctg attgttttcc agatcaaaat ccggattatt taacatggga ttaatgccaa
    37501 gaattccgtt aggctgaagg cgaaatccgg gcttggttaa atttatctca tcggtgtatg
    37561 taaatcccat ctttctggcg ccatagagaa aaagatcttc ttttgacgtt gctgtagctt
    37621 cgcggactgg aagagtctgc tccacctctt cataataggg aatcatttcc tcataactga
    37681 ttggccagtc acgttcaaat gcagcagggt aagcacgggg acagttggca aaatacaaaa
    37741 gtgtgcttcc tcccacgcct gcactctgcc agacaaaacc gcccttctca acgattctgc
    37801 gccacggact tgtacttctg tccgctggcc cccatctgaa ttttcctgta atggcgtcat
    37861 tcatgtcatc ctctaaatca gtaaagttgg ttttaagaag ctgaatatcc agatcttcgt
    37921 tgcttgaact ttcctgagcg cctgcactgg tattgggctc cggccacttc cggttgccat
    37981 accagggtcc tgcctcaaga atcagcacct ttaatccctt ttctcccagc tcttttgctg
    38041 cgactgcgcc tccgcctcct gatcctatca caattacatc cgcatcaaat ccgttctcca
    38101 tacgcacctc cagtcaatat cgattcctta ctttctctgt gcaaaattaa aagctcctgc
    38161 tatccggtat cccttagaag gtcccggata ccccacctgt tcccagccga ttggcttata
    38221 ttccagcatg cgcttatccg gggacataaa tcttgtggat ccgtagccgg accactcaga
    38281 ataatatccc atcagagtaa gccggtttaa tgccgacatg actggaacga tgtcttcctg
    38341 tttcatggta agacctgcag gtacataaat gatgccgcct gggctgctga tccggtcaac
    38401 aatcttcagc ctgtcttcct gagataattt tgagaaataa agtcctcctg aatcttttgg
    38461 cacatccggg tcctctccct tttccatcag atattgtttt gctgccatat ttaatatttc
    38521 cgccacagcc actgcaaagg gcgtaggata gctgtcaaga gacatgatta aatactccgc
    38581 cgtataggat tccactgctc cgtaaaactg aatccttcca tatagttccg ccagatccgg
    38641 tgaatggggc accatggcat ctgcataggc tttcattgta ttaacaacgt aatcgtagac
    38701 tgaattctca tcccataatc cattttttaa accatcactg ttttcagcca atgttccacc
    38761 tgattccttc caaaatgcat gttcataaaa tactatgaaa acctttgaaa aaagtatcac
    38821 atttcctatc atcctatttg atacaaaaaa accggcctgt gccggttttt tattagtctg
    38881 cagcttatta ccagtattac agctttagcc ataaagcggg acgaacgccc cctctgcatt
    38941 cgccatcgct tagatttcca attaatatat tgttgccctg aatccctata ttaccatcac
    39001 catggatata tacggccttt acaccaacac ggcctgggga acgcagccac caccagtcgc
    39061 tgcctttttc cccctcgcgt ctggcaattc tcttactgtt gttcttatct tttcgttcaa
    39121 accaatacct ttggttcctt ccaggattat agagctttaa gctgctgtca ccaaaatacc
    39181 ggcacgctgc ttcctccata cttaataaaa aagatggtat cccgggtatc ggccccgcct
    39241 tcacaaccat accactcatt atccggattt ctgtttagga caggaatcat cctggattgt
    39301 tcctctacac tgaatctgtc atggaattca ccgtttaaat acgctctaac tgcacagtcg
    39361 gcccatgttg tctctttata aatattatgg taaggacgcc gttctatgat gtattcggtt
    39421 ataatcaatg ccctgtcttc cagtagttcc agtacccgcc attggtagtt cccaaacgaa
    39481 attttatctc ctgtctgcat gttaccccct gtacaaatat tatttgcatt atttcgcaat
    39541 ctttatctgc attgtaacat ggcttatttt aaaaggcaat catcctgctt tagctgtctt
    39601 tttctgtgag acaaaaatac tggctatgat gattgcaaca ccaacaagct gaatggggct
    39661 gatgctttgc cccagcacca catagcctaa aacaaatgcg gttaagggat tcaccggact
    39721 taaaagtgat acacgtacag gggaaaggat ttcgattccc cggaaccata agtaataggc
    39781 tagtccggta ttaaccactc caagtatggc aagtccagca atattaacag gagtgagggc
    39841 gggtatgctg ccctccatga taaacactgc cggaatcaga atcagactgc caaaaaacag
    39901 ctgccaggaa gtaaacacca tctggctgat tccttccggt tttccccagt acttggtcag
    39961 caccacgccc agggccatta ccactgcacc gcataaagca gctaacacgc cccatacatc
    40021 aattgccatc tgctgcttaa acagaagtaa tatgactccc gtcaccatca taacaattgc
    40081 agcataagac cgcatggttg gtttttcttt taaaagaacc cagctgaaaa atattacaaa
    40141 taccggttgt acgcttccta tgatcgatgc gatccctcca ggcagccggt aagccgcaat
    40201 aaacaaaaac agaaagaata ttccaatatt taagctacca agtatcaatg attttaaaat
    40261 ccagattccc ttgggcagtt tcctgtaata taaaagcaaa atcagtccta tgggaaatgc
    40321 tctcataaat gcaacaaaca ccgggcgctg tatggggatc aataccgagg caatgatata
    40381 ggtggatccc catagcatgg gagtcagcat tgtaagcaat atatctttca tctgcttcat
    40441 ttttttatcc tcttttcctt attatttatc tcacgtttaa gtatcttaac tttaagatat
    40501 attaagtgta tcgcttgtca tcttgattgt caagtatttt aatgttaaga tatttaaaat
    40561 taagaaactt tacattaaaa tttccttgta cttttttatt acaggtgtta cactaaaaat
    40621 atgaaaaaag ataatgttga taaaataatc gatcaatggg ctcttgagct tccggatctt
    40681 gatgcgtcac cgatggcggt ttggggaaga cttaaaagaa ctgtcaagta ttcagaaagg
    40741 agattggcag agaatttttc cctttatcag ttaaacagcg gtgaatttga tgtgttggca
    40801 acactgcgtc gttccggcgg tgaattcaaa ttaaaaccca cggatctgta tcagtcactt
    40861 atgatcacct cgggagccat tacaaaccgc attgatacac ttgagaaaaa agatttggtt
    40921 aaaagagttc acgacagcga agacagaaga acgatctatg ttcagctgac caacgcaggt
    40981 tatgaattaa tatcccgggc ggtcatatcc catacccagg cagaagaatt cctgttaaaa
    41041 gggctgacaa aagaagaact ggcccagttg gaccagttat tgaagaaact tctttcatcc
    41101 ttggaagaac agtaagaccg gcaatgtcag attatgactt tagtcggtca tatttctgat
    41161 aaatcctcat acagtcatcg agcagttcaa ggagtgtata aagctgggac agcttttttc
    41221 tcccttcggt aaagccctgt atatcctccg cttttcttaa tgcttttctg ttttccccag
    41281 tcagcctgtt aattgcagtt cttacccctt ctgcggcaga ccgggatacc tctttaaaga
    41341 cataaaatat ctggatcgct gttttctgca ctgcctccat ataggcattt atctcttttt
    41401 cgctggctgc aagattcttc tttctgataa ccagcgcctt gcctttttcc gataattgag
    41461 tggatcgctt cggatccgca gcttccccta ttttttttaa ctcttccgca tctttttgaa
    41521 agcttttgat ttcttcttcc agtttcgatt tcttttcttt tagattcctg atctcgggga
    41581 tcatggcaag cagtgtctgc tctaagttaa atatgctgct ttgcagaatc tctaactgaa
    41641 gaacaagctg tgattccagc tgcaggactt ctctttttcc ccaagaagct gggttatggc
    41701 atggtgcatc cggggaatct cctctaccgc ttttgaatgg acaaacgtat cggtgtcagt
    41761 cacctcatcc tgataggaat aatcccatgt cagttcattt agaatttcat tccataagtt
    41821 aagatttgcc tgtactcgtt tcgccttttc cgtgacaacc acaaaggttt ccacttcatc
    41881 tttcagttgg tcaatctcag ttcttactga gacagccagt tccgcaatat cctttaaatt
    41941 aagattgatc ttagaggcaa gacttttcag ctcttgcgca tatggaggca cttctccggc
    42001 aggtatgtat tcctccacaa ttttatccag ggtaaaatga agcggttttt ttaagctgcc
    42061 tttttcaagc agtctgacca gaaatcccat tttgacatcc cttcaggaat tatgcacgca
    42121 gtggtatctt accttacttt atgcctcctg agtcttatta ttgcaaagaa cactacctta
    42181 gaataccagc gataacaatt tagctgatca gatatggttt cgtcaaatcc tcaaactctt
    42241 tctggtattc tttcagataa tccataaaat acattccttt tgtatctaat acctgggaga
    42301 gtttcaccat aaaatccgga atatcttcct ttcttaatgc acccatgcag ttccccatat
    42361 gggttttatc tttctccact gctccaccta catgaagttc aaaggcctct gccggagcat
    42421 cggaaatacg ttttttacag ccagcaaatc caatttcact tacctggtgc ctggaacagg
    42481 aattaaaaca ccctgatatg gaaacagaag gcagataatc cgtgttaata ttatgttcca
    42541 tcagtgccct gtttatttct tttaataatg tctggctctc taaaacgcct atctggcagg
    42601 ttggcactcc cacacagctc acactcatac caattcttgt aaccttattg atctcttcca
    42661 ttcttgcaag gagcttttct ccttcttctc tggacaggtt gcggatgtac atgctttccg
    42721 acatactaag gcgaatgtcc tgctgtttat ccatcaaatg aaatgatttt ttccagggct
    42781 tttacaggca gctgtccgca ctggggatga ataacagctg tgtaaaatcc cgcctgtttt
    42841 tgggggatca gattactgct gtctgtatgg atatctgctg actgcacctt aacttctgtt
    42901 ttacatatcc cggctgcttc cacattaata gttaagtcca tggattcctt tacctgggcg
    42961 agatgctttt tgtaacaatc catgaacgct tcttccccca tcctttttgg gatgtatctt
    43021 agtcttgctt ttcccttgtt ctcataatct ccttctgccg caaatattct tgtaacagct
    43081 tccacatgat acagaacctg atttgggggg aatcaattca tcatatggta aagccactgc
    43141 aggattgttg cctaatccgc ctgccagata cattttaaaa gaaggggttc cctgatccat
    43201 gactgccata aagcccaaat cattgatggt acagttagct gtatccgcct cgttgttgga
    43261 aaatgctatt ttcagtttac ggggcaaatg atattccata atccgctcca tgacgtaccg
    43321 gttcacctgc tgcgcatagg gagtgggatc aaacgcttcc gttttatcca caccagacag
    43381 gggagacaat gcgacattac ggggataatt gccccctcct cctcttgtat acaaaccatg
    43441 gtcaatggcg gtttccatga tatcacagac agaatcaata tccagatcat gaagctgaat
    43501 ggcctgcctg gttgtaaggt gaattctctc taaaccatat tgcacggcaa atttatggat
    43561 taatttcaaa tgggaaaatg ataagatccc gcagggtatc ctcaaacgaa tcataaaagc
    43621 tttgccgccc ctttgcgcat aaacacccat gcctccggat ttccccttaa attcagcgga
    43681 cgtaatttct ttattcacga acttatgtcc ggcttctctg aattcagcta tttcctcttt
    43741 tagtttttca ttgtattcct tcaatgtttt tctcctatta acctatatga tttaatagtt
    43801 ttatattatc ataaaacagg aatagaataa aatatttttt ttattttgtt tcacaaattt
    43861 gttttaattt tttgttcatc gcttcaaatc ccgcttttgt tccattatcc agtgactttt
    43921 ttaacatcgg caataagatg ccattaaatt tctctctttg gatgaatgtc gtagtgccat
    43981 ccgaattctc gattaattct aatatatgct caccatcaaa taatcccgga aaaccggtgt
    44041 gcccaagcca tcgaaattct ttatctttct gaaatttcaa aactgtaggt ttaaaaacca
    44101 tcccttttga accgggcgga accatcttaa cttctattct ctctcctact gccggttttc
    44161 cctttaaata taccataaat ggattccagt cgggaaaagc acgaaaatca gttaaaacat
    44221 accatactgc acttgcagat gcattaattc gtatctctgt tcttatttct ttcattcgca
    44281 tttcctcctg agatatgact ataatatttt cactgagcaa acagtgaatt attatttata
    44341 atgagtacct ggaacctata ttgctatagt tcccaggtta aaagtgtgta ttcaacgacc
    44401 tgaatcagat agtgttcccg gtcactgtga taaaaactgt gattaccaaa aaatacatcc
    44461 tgtaaaatgt aggaataaat cgcactccaa aact
//
