LOCUS       NZ_CP070499            23020 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Natronosporangium hydrolyticum strain DSM 106523 chromosome,
            complete genome.
ACCESSION   NZ_CP070499
VERSION     NZ_CP070499.1
KEYWORDS    RefSeq.
SOURCE      Natronosporangium hydrolyticum
  ORGANISM  Natronosporangium hydrolyticum
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Natronosporangium.
REFERENCE   1  (bases 1 to 5699854)
  AUTHORS   Sorokin,D.Y., Khijniak,T.V., Zakharycheva,A.P., Boueva,O.V.,
            Ariskina,E.V., Hahnke,R.L., Bunk,B., Sproer,C., Schumann,P.,
            Evtushenko,L.I. and Kublanov,I.V.
  TITLE     Natrosporangium hydrolyticum gen. nov., sp. nov, a haloalkaliphilic
            actinobacterium from a soda solonchak soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5699854)
  AUTHORS   Sorokin,D.Y., Khijniak,T.V., Zakharycheva,A.P., Boueva,O.V.,
            Ariskina,E.V., Hahnke,R.L., Bunk,B., Sproer,C., Schumann,P.,
            Evtushenko,L.I. and Kublanov,I.V.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-FEB-2021) Bioinformatics, Leibniz Institute DSMZ,
            Inhoffenstr. 7B, Braunschweig 38124, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-MAY-2020
            Assembly Method                   :: HGAP v. 4
            Assembly Name                     :: 999_Micromonospora_sp_DSM106523
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 580.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016925615.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 06:45:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,188
            CDSs (total)                      :: 5,131
            Genes (coding)                    :: 5,046
            CDSs (with protein)               :: 5,046
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 85
            CDSs (without protein)            :: 85
            Pseudo Genes (ambiguous residues) :: 0 of 85
            Pseudo Genes (frameshifted)       :: 18 of 85
            Pseudo Genes (incomplete)         :: 72 of 85
            Pseudo Genes (internal stop)      :: 4 of 85
            Pseudo Genes (multiple problems)  :: 8 of 85
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:11:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4428671
            Orig. end                         :: 4451691
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070499.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23020
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23020
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23020
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13020](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13020
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    190..203
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.89"
                     /tool="antismash"
     misc_feature    complement(191..204)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            482..1786
                     /locus_tag="JQS43_RS19880"
                     /old_locus_tag="JQS43_19805"
     CDS             482..1786
                     /EC_number="3.5.3.13"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013284365.1"
                     /locus_tag="JQS43_RS19880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19805"
                     /product="formimidoylglutamate deiminase"
                     /protein_id="WP_239675890.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.5e-49, bitscore:
                     167.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRFHAELAWLGDRPAPEVLIEVDSGRFTTVAPDTAQPADARRLP
                     GLTLPGFANTHSHAFHRALRGRTQGGAGDFWSWRERMYSVADQLDPASYAALAAAVYGE
                     MALAGITCVGEFHYLHHQRDGRPYADPNEMATALVEAAERAGIRLTLLDTCYLTADVAG
                     APLTGPQRRFGDGDADAWAARVARLRPAGHWQVGAAIHSVRAVPADQLPVVAGWAEQAA
                     APLHVHLSEQPAENEACLARYGVTPTALLADAGALGPRAIAVHATHLTSADRRLLGAAG
                     AGVCFCPTTERDLADGIGPARALVDAGARLSLGTDSHAMIDMFEEGRAVELNARLADQR
                     RGHFRPDELIAAATVAGHQALGWEDAGVIAPGARADLVTVALDSVRTAATDPAAVIFAA
                     TAADVTQVVVDGRQVVADGRHLAMDVPRALEEATP"
     misc_feature    1562..1564
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1783..2946
                     /gene="hutI"
                     /locus_tag="JQS43_RS19885"
                     /old_locus_tag="JQS43_19810"
     CDS             1783..2946
                     /EC_number="3.5.2.7"
                     /GO_function="GO:0050480 - imidazolonepropionase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006548 - histidine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hutI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020514207.1"
                     /locus_tag="JQS43_RS19885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19810"
                     /product="imidazolonepropionase"
                     /protein_id="WP_239675891.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1e-15, bitscore:
                     56.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLVDNIGELVTNDPSYGDDPLGILRDAAVVIEERRVAWLGPGA
                     EAPAADDRVDAAGAAVLPGFVDSHSHVVFAGDRAAEFAARMAGEPYTGGGILTTVAATR
                     AASDAELRATAGRLRAEALRQGTTTLEVKSGYGLTIADETRSLRIAFEVTPESTFLGAH
                     LVPPEYADRPDDYVELVCGPMLTAAEPYARWVDVFCERGAFDADQSEAVLRAGMALGLA
                     PRVHANQLGPGAGVQLAVALGAASADHCTHLSDQDIAALAGSDTVATLLPGVEFSTRSP
                     YPDARRLLDAGATVALASDCNPGSSYTSSMPLCIALAVREMGMTAGEALWSATAGGARA
                     LRRDDVGTVRLGSRADLVLLDAPSYLHLAYRPGVPLVRQVIHNGVLM"
     gene            2943..4481
                     /gene="hutH"
                     /locus_tag="JQS43_RS19890"
                     /old_locus_tag="JQS43_19815"
     CDS             2943..4481
                     /EC_number="4.3.1.3"
                     /GO_function="GO:0004397 - histidine ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006548 - histidine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hutH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014441067.1"
                     /locus_tag="JQS43_RS19890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19815"
                     /product="histidine ammonia-lyase"
                     /protein_id="WP_239675892.1"
                     /transl_table=11
                     /translation="MSVVEILPTGVSPADVVAVARGDATVELSAAASAAMTDSRAIVAE
                     IERQERPVYGVSTGFGALANTFIDPQRRTELQHALLRSHAAGVGARMPTEVVRAMLLLR
                     VRSLAKGLSGVRPVVAERLIDLLNHGITPWVPEHGSLGASGDLAPLAHCGLVLTGEGWV
                     VGKDGARLPAGQVLGEAGLAPVELAAKEGLALINGTDGMLGMLLLAAEDAAHLFTMADV
                     TAALAIEAMLGTDRPFQPELHAIRPHPGQRDSAGNLARLLRSSAIMDSHRDDLEHAVQD
                     AYSMRCAPQVAGAARDTLAFAVGVADRELASVVDNPVVLPDGRVESTGNFHGAPLGFAA
                     DYLAIAAAEVGAISERRVDRLLDVTRSRGLPPFLTPDPGVNSGLMIAQYTAAGLVAENR
                     RLAAPASVDSLPTSGMQEDHVSMGWAATVKLRTVLDNLTSLLAVELLAAVRGLQLRAPL
                     TPSPAGQAAIAAVSEFFGEPGPDAFLAPAMESGRAVIKGRELRAAIEAAGPPLA"
     gene            complement(4426..5103)
                     /locus_tag="JQS43_RS19895"
                     /old_locus_tag="JQS43_19820"
     CDS             complement(4426..5103)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JQS43_RS19895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JQS43_19820"
                     /product="hypothetical protein"
                     /protein_id="WP_239675893.1"
                     /transl_table=11
                     /translation="MRRVLVVAAAVTPAVLAVLLGLGTAVYWWATSEPEDEWARFTEAT
                     EVQELVIAVERDRERVRSGKQTTYTIAVGNRGQAAQPVTVRASVPPWLTPTGATADNGY
                     VEWSLVVPPGGVETTRLVGVYAAPRSAADPAGGAAPVVGTPQRVTFTACALDQAAGEPI
                     VCDTDATHLAAPISGSSLGWLALGAGTLAVATAVAAATVIRAGTLRRVADRLPRWRRAA
                     RGP"
     misc_feature    complement(5175..5188)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            complement(5249..5431)
                     /locus_tag="JQS43_RS19900"
                     /old_locus_tag="JQS43_19825"
     CDS             complement(5249..5431)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JQS43_RS19900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JQS43_19825"
                     /product="hypothetical protein"
                     /protein_id="WP_239675894.1"
                     /transl_table=11
                     /translation="MASQGESTTFWLGGAVAIGLVMGLVLGFATSVYGGVIAGVAAAGV
                     WFIVGALRRRRAARP"
     misc_feature    5412..5426
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.42"
                     /tool="antismash"
     gene            complement(5510..6127)
                     /gene="rdgB"
                     /locus_tag="JQS43_RS19905"
                     /old_locus_tag="JQS43_19830"
     CDS             complement(5510..6127)
                     /EC_number="3.6.1.66"
                     /GO_function="GO:0035870 - dITP diphosphatase activity
                     [Evidence IEA]"
                     /GO_function="GO:0036222 - XTP diphosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="rdgB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018786676.1"
                     /locus_tag="JQS43_RS19905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19830"
                     /product="RdgB/HAM1 family non-canonical purine NTP
                     pyrophosphatase"
                     /protein_id="WP_239675895.1"
                     /transl_table=11
                     /translation="MTATHRLLLATRNRHKLTELRRILTGVGSVELVGLADVPEYPEAP
                     ETGLTFAENALLKAREGLRHTGLPTIADDSGLVVDAFGNAPGVFSARWAGRHGDDEANL
                     QLLLAQLADVPDANRQASFVCAAALALPGGREHLVDGRQPGVLTRGPRGGGGFGYDPIF
                     VADGETRTNAELDPAEKDAISHRGQAFRAMGKLIARVLIDGS"
     gene            complement(6124..6849)
                     /gene="rph"
                     /locus_tag="JQS43_RS19910"
                     /old_locus_tag="JQS43_19835"
     CDS             complement(6124..6849)
                     /EC_number="2.7.7.56"
                     /GO_function="GO:0004549 - tRNA-specific ribonuclease
                     activity [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rph"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012181215.1"
                     /locus_tag="JQS43_RS19910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19835"
                     /product="ribonuclease PH"
                     /protein_id="WP_239675896.1"
                     /transl_table=11
                     /translation="MTRPDGRKPEQLRPVRLTREWSSHPEGSVLVEFGDTRVLCTASVT
                     EGVPRWRRGSGQGWVTAEYAMLPRATTSRNDRESVKGRIGGRTHEISRLIGRSLRACID
                     LGALGENSVVLDCDVLQADGGTRTAAITGAYVALADAVSWLSNRQRLRKAPSVVLHRSV
                     AAVSVGVVEGEPRLDLCYAEDVAADVDMNVVCTSNGDFVEVQGTGEASVFSRSELDAML
                     ELAVAGCAELSEAQRVVLT"
     gene            complement(6836..7831)
                     /locus_tag="JQS43_RS19915"
                     /old_locus_tag="JQS43_19840"
     CDS             complement(6836..7831)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018255064.1"
                     /locus_tag="JQS43_RS19915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19840"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_239675897.1"
                     /transl_table=11
                     /translation="MIETGLTAGEAARRLGVAVTTLRSWHHRYGLGPTQHEAGHHRRYS
                     ADDLARLELMRTLTSQGVPAARAARLARAGAPAPGSGRATAARALPDHPGHGPADEPEA
                     VSSAAVRGLVYAAERLDIGSVRRVVSKAVADLGAAAAWDGLIRPALGRIEAKQAGPHGS
                     AGGLVAVEHLLSRGISEVLGAVPRPATPPQALLTCAAEEQHSLPLEALAAALAQREINA
                     WLLGARLPAPALAAAARRTGPGLVVVWSHARRTADPAPLVALIASRPRPAVVAAAGPGW
                     SQPLPAGVTSLASLPEAVAAAVAVASAAPPAEPGASHAAGLTYGGGHDAT"
     gene            complement(7828..8394)
                     /gene="idi"
                     /locus_tag="JQS43_RS19920"
                     /old_locus_tag="JQS43_19845"
     CDS             complement(7828..8394)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730891.1"
                     /locus_tag="JQS43_RS19920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19845"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_239675898.1"
                     /transl_table=11
                     /translation="MIPDLDRALLPVELVDSGGDPIGSSTVLRAHTAPGQLHRAFSVLL
                     LALDGQRLLLQRRAAVKTRFPLRWANSCCGHPAPGQSVVAAATDRLAEELGVTGVELRE
                     VGVYRYRATDPASGWVEYEYDHVLVGQIPLDQRLAPDPAEVAELWWVAPVELHRLLEQQ
                     PAACAPWLAGVAAPLDTVAGKHWGG"
     gene            complement(8391..9872)
                     /gene="crtI"
                     /locus_tag="JQS43_RS19925"
                     /old_locus_tag="JQS43_19850"
     CDS             complement(8391..9872)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014440266.1"
                     /locus_tag="JQS43_RS19925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19850"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_239679505.1"
                     /sec_met_domain="DAO (E-value: 4.2e-16, bitscore: 57.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQVTGATERVVVVGAGLGGLACALHLAGAGRQVTVVERAAEPGG
                     RAGRLALAGFEFDTGPTVLTMPDLIAEPLAAVGESLTDWLPLTTLDPAYRAWFPDGSSL
                     DVITDPERMAQQLAEVCGPREAAGYRRFVASARQLWQLERDDFIARNLDAPTDLLNGNL
                     LRLLAVGGFGRLQAYIDRFFRDPRTRRIFSFQAMYAGLAPHRALAIYAVIAYLDAVCGV
                     YFPRGGVHALPRALAGAADKHGVELRYDTTVTRVETRAGRAVAVHTTGGERIPADVVVL
                     NPDLPAAHELLPGPGLRRRLRYSPSCVVVHIGSRQHYSKIAHHNIHFGRAWRRTFQEVI
                     DEGRLMSDPSLLVTNPTRTDPQLAPAGQHSYYLLAPAPNLATGAQAWRSGLTDAYVSQL
                     FEVLEARGYHGFRDAATVCHPVTPADWADQGLAAGTPFAAAHTFAQTGPFRPNNLHPAL
                     DNVVFVGSGTQPGVGVPMVLISGKLAAARVTGAAR"
     gene            10001..10915
                     /locus_tag="JQS43_RS19930"
                     /old_locus_tag="JQS43_19855"
     CDS             10001..10915
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785446.1"
                     /locus_tag="JQS43_RS19930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19855"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_239679506.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.8e-106,
                     bitscore: 353.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.1e-66,
                     bitscore: 222.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPALAAAYQRCRQLHRHHGRTYYLATRLLPRHKRPHVHALYGFT
                     RYADEIVDRTEDLPPDKRAERFREWSETFLAGLAGAPVTDPLLPAVLHTIDACQLDPDD
                     FAAFLKSMAMDLTVTEYQTYEELLSYMEGSAAVIGTMMLPILDPTDPAAARGPARELGL
                     AFQLTNFIRDVGEDLDRGRIYLPQQDLARFGVTPAGLRAAAARGSADPAIRSLIRYQVT
                     RAHQHYAAAAPGVTMLTPSSQACIRAAYHLYAEILTEVARVDFDVFRRRAVVPRARRAR
                     LAARSLLTRAGTPVTPPGARRPA"
     misc_feature    10121..10123
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10912..12273
                     /locus_tag="JQS43_RS19935"
                     /old_locus_tag="JQS43_19860"
     CDS             10912..12273
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454368.1"
                     /locus_tag="JQS43_RS19935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19860"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_239675899.1"
                     /transl_table=11
                     /translation="MTREATPAVLLFTRDLRLDDNPALAAAARGPVLPLFVVDPRLPAG
                     ENRRHFLAECLTDLRESLRQRGADLLVRRGDPVHEAISLAKQIGAGAIHLAEDVSGYAT
                     RRQRRLLTAADSARLTVHLHPGITVVPAGDLVPASGDHYRVFTPYFRAWRQIRWRDPAA
                     APAALSLPPGAADLPRQEPAAALGRIRATARTLPTGGESAAEAAFRQFGRYAAEYPERQ
                     DDLAADRTSRFSAYLHFGALSARRVATSPAMPEALVRQFCWRDFHHQVLAAFPALPWEP
                     YRRRADTPDGVDRGGAAPADADTLAQWREGSTGLPIVDAGMRQLQAEGFLPNRARLITA
                     TYLVKRLRGDWRDGAAWYDDQLVDADLANNYGNWQWVAGTGNDTRPHRGFNPLRQASRF
                     DPAGEYVRRWLPELAEVTGPQVHEPWRLPEPVRRGLRYPMLDPATLDPATPRSR"
     gene            12273..12644
                     /locus_tag="JQS43_RS19940"
                     /old_locus_tag="JQS43_19865"
     CDS             12273..12644
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018353503.1"
                     /locus_tag="JQS43_RS19940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19865"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_239675900.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 2e-19,
                     bitscore: 68.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRWHYVLILAACLLITLPLELLPGVRVYRRPKLLLASIAPVLVI
                     FVGWDLLAYHHGHWWFSDQYTLGPRLAGLPLEEWLFFVVVPLCALLTYEAVGSVLARGR
                     GAAARRATAAPTTAGGSDA"
     gene            12637..13020
                     /locus_tag="JQS43_RS19945"
                     /old_locus_tag="JQS43_19870"
     CDS             12637..13020
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03462.1"
                     /locus_tag="JQS43_RS19945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19870"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_239675901.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 3.2e-17,
                     bitscore: 61.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDLPLYTVAAVAAPLLVVALELLVLRTGLFRTLRYWLTMLIVLG
                     FQIPVDGWLTKPQGTVVLYDEAQILGIRAPVSFPIEDFGFGFAMVTLTVLLWRWLRNRE
                     QRRPAPPAAAQQSPARTAEQASA"
     gene            13013..13708
                     /locus_tag="JQS43_RS19950"
                     /old_locus_tag="JQS43_19875"
     CDS             13013..13708
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013702.4"
                     /locus_tag="JQS43_RS19950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19875"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_239675902.1"
                     /transl_table=11
                     /translation="MRERSPTASAMFQGFRWLVRQSLRGVWWRGDPPAGPFVWAANHHS
                     WWDPFIAAALLERWRRVGCLLLSQTNLERYRFIERLGGFGTGEYRRGLSYLRAGRVLII
                     FPEGELRPPGPLGRLAGGAGWFAHTAKVPLYAVATRVVVRGQQAPEAYLSLAQVAPPTG
                     LASRDAARELTGRLTTTLTDELAALDAAVASADPRQPLPGFTRAVAGRRSWDERIDRVH
                     RWLPWRPER"
     gene            13714..14796
                     /locus_tag="JQS43_RS19955"
                     /old_locus_tag="JQS43_19880"
     CDS             13714..14796
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /locus_tag="JQS43_RS19955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19880"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_239675903.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.3e-19,
                     bitscore: 68.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGALPALVAGFHLTKTVGLLDNLASFPVLGRRPSAAPPLPRVSL
                     LVPARDEADRLPRCLPGLLAQPAAEVLVCDDESTDDTAGVVRRAAADDPRLRLVPGTPR
                     PPGWIGKSWACHQLAAAATGDLLVFCDADVLLQPGALAALWAELTRQRSEVFSVFPRQQ
                     TGTLGERLLVPLIDEVLLSFLPHRLLSLPVPAAATANGQLLAFRRSAYQAIGGHRAVAD
                     RIVEDLALGRLARRRGLRLGLALGGDLVSARMYDGYPQTVRGLGKSMREAHGDRDALLL
                     ASLGWHLLAYTVPWLRWRSAPGWRLAATLSVAQRLLVNAKTGRGSPWEALLVPVTAPAA
                     IPVYLLAARRRARWRGRSYP"
     gene            14793..15959
                     /locus_tag="JQS43_RS19960"
                     /old_locus_tag="JQS43_19885"
     CDS             14793..15959
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="JQS43_RS19960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19885"
                     /product="cytochrome P450"
                     /protein_id="WP_239675904.1"
                     /sec_met_domain="p450 (E-value: 1.2e-27, bitscore: 95.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTLRSPARLPQPPGHPVIGHLWPWTFAPVPLLAAGARTGEVF
                     RLRLWRSTLVGYRPEWNRAVLGDLDTFRSRGSLSGLTPYLADGVVHTDLPAHAPHRRAL
                     NPHFHSQAVRQLTDRLRAAVQSGLPGRYFDALPWAGSVVRRMLSAALFGDRIPQSLLER
                     FLAPLHRPNPAPLLPRPRLFRRMNTAIAAVVADPVPGTLAAAVAGEAAAGGDLDPVAEL
                     RVALAAGYDTTAHTLAWTLWWLAGSPAWRDPESLPMVLDEILRLYPAGWLGSRVAARDT
                     EVCGVAIPAGTMVCYSPYLTHRDPGLWPEPDQFRPDRFTAGRPAWGFIPFAAGRRTCLG
                     AQLARAMLTCASEPFLAGPLRQLNGDPSVVAGITLRPHGPLWLSWRGE"
     misc_feature    14895..14897
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15270..15272
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16012..16941
                     /locus_tag="JQS43_RS19965"
                     /old_locus_tag="JQS43_19890"
     CDS             16012..16941
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020519184.1"
                     /locus_tag="JQS43_RS19965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19890"
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="WP_239675905.1"
                     /transl_table=11
                     /translation="MSWLPLPLIRRCQRLAYRFWCRLQRRHGSVRRLVRAGKRYRQADG
                     RRLAAAVSYYGFFATFAMVLLGFAALGYVVDDPGVQGAVQRFLDENLPRVDTDAVRDAR
                     EATGLIAFASLLVIGLLWVDSLRSSVRAIWRIEEYPGGFFRRWFIDGLALVGLGTLLAV
                     SLTVALGAEALLGWLVELIRAGELAPAEWLLLVVRFGLNFSVNTILAIAALTLLPRLRM
                     PLRRVLPPALLVAAGAEFLTSVGRLVVDRAEYNPAFQVVAGAAGLLVFLLILNQLILFA
                     ASLTATAEQGRVVDLARRNGLRGSYYAS"
     misc_feature    16021..16023
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16929..17372)
                     /locus_tag="JQS43_RS19970"
                     /old_locus_tag="JQS43_19895"
     CDS             complement(16929..17372)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JQS43_RS19970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JQS43_19895"
                     /product="hypothetical protein"
                     /protein_id="WP_239675906.1"
                     /transl_table=11
                     /translation="MTDPRGFVMAHASAPQSQRARGWAIGGLVFGATVMLIIGFWQALM
                     GIAALAAEDFFVVSPEYAYEIDVTTWGWIHLGIGVVVFLVGLAIFTGAMWARVVGIALA
                     IVVAVANFFFLPYYPLWSLVVIALAIFVIWALAAAPRMIDQDA"
     gene            complement(17369..18583)
                     /locus_tag="JQS43_RS19975"
                     /old_locus_tag="JQS43_19900"
     CDS             complement(17369..18583)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692083.1"
                     /locus_tag="JQS43_RS19975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19900"
                     /product="glycosyltransferase"
                     /protein_id="WP_239675907.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 9.7e-23,
                     bitscore: 78.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIALITESFAPDVNGVANSVGRVADHLYRAGHQPLVIAPAPAST
                     RRRVAGPRPYPVVRVPSVPTPGYRGFRIGVPGPALTDALIAHAPDVVHLASPFVLGARG
                     GGLAASLGLPTVAVYQTDMAAYLRLYGPGRWRRAPAEMLAGRRAPAEILAWRWLRRIHN
                     TADLTLAPSKAAAAALSAQGIERVRLWPRGVDLDRFSPARRSERLRRLLAPGGELLVGY
                     VGRLAPEKRVELLGAVCRLPGVRVVVVGDGPSRPALARALPGAVFLGERHGHQLARIYA
                     SLDVFAHTGPHETFGQTVQEALASGVPVVAPAAGGPMDLVTPGLTGALVPPADAGAIAA
                     VVAGLRADPGRRDAYARAARESVAGRSWSAIGDLLLDHYYEAIGIDLPGKPSQKRTTLA
                     YAQGR"
     gene            complement(18700..19449)
                     /locus_tag="JQS43_RS19980"
                     /old_locus_tag="JQS43_19905"
     CDS             complement(18700..19449)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012181213.1"
                     /locus_tag="JQS43_RS19980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19905"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_239675908.1"
                     /transl_table=11
                     /translation="MRLTVLGCAGSFPGPESACSAYLVEAEGFRLLLDFGTGSLSALQR
                     YIGLMSVDAILLTHLHCDHVLDACSYVVVRRYAPGGPYPPIPVYAPAGAPDRLAAAYTP
                     EATPLDDVYTFYGLQPGTFPLGPFTVTVDQVNHPVETYGVRLEHGGGTLTYSADTAKCD
                     SLLRLAQGADLFLCEASYLDDVPHPPDLHLTGGEAGEVASKAGVGRLLLTHLVTAWGSE
                     AATFEAASAAYPGPVEIVRPGARYEIG"
     gene            complement(19446..20267)
                     /gene="murI"
                     /locus_tag="JQS43_RS19985"
                     /old_locus_tag="JQS43_19910"
     CDS             complement(19446..20267)
                     /EC_number="5.1.1.3"
                     /GO_function="GO:0008881 - glutamate racemase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="murI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020525431.1"
                     /locus_tag="JQS43_RS19985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_19910"
                     /product="glutamate racemase"
                     /protein_id="WP_239675909.1"
                     /transl_table=11
                     /translation="MSPNQEAPIGVFDSGVGGLTVARAILDQLPMEQLRYLADTAHVPY
                     GPKPIAEVRRHALAGLDTLAASGVKALVIACNAATAASLHDARERYQVPVVEVIRPAVR
                     RAVAATRNGRVGVIGTQATISSGAYQDAFAAAPQVRVTTAACPQFVDFVERGTTTGRTL
                     LGLASAYLEPLQRAQVDTLVLGCTHYPLLAGMIGLVMGESVTLVSSADETARDVYRVLT
                     QTGSLRAADSPPPRHQLRTTGDAAVFRRLAQRFLGAELMELTAPEFAGVAE"
     gene            20492..21220
                     /locus_tag="JQS43_RS19990"
                     /old_locus_tag="JQS43_19915"
     CDS             20492..21220
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JQS43_RS19990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JQS43_19915"
                     /product="hypothetical protein"
                     /protein_id="WP_239675910.1"
                     /transl_table=11
                     /translation="MRTTTVARPRRRRPRPTTRAPRAVAAAPHPAPPATDRGAAAQTDP
                     STDQPTAAAKPAARRRLIRGAGWLQPLLAALRPAAHQLGWHTGRLGHAARYRATAWSNR
                     MARAWHRRTASDRTLGRPPLGRLLASELSRRLPSWLRPRDPTLAGVRDTPPPPGRLAGM
                     CTWAALLGLLGLPLAGRALLTVAAGSRPDWSDPGMLTGVLGIGLAVAAFLVAHRRRAPW
                     LLLGLATLLLAAGPRLFGGE"
     misc_feature    complement(22932..22947)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.23"
                     /tool="antismash"
ORIGIN
        1 gtggcgccga acgccaccaa cgccgtcccc gcccgggtca ccgcctggct ggatgcccgg
       61 gcgcccgacc agcagacgct caccggcctg gtcgaggcgg tgacggtgcg ggcgcaggac
      121 cgcgccgacc gggacggcac cgccgtgacc gtcgccgccg agtcggtcag cccggtcgtc
      181 gacttcgacg tcacgctgcg ggaccggctg gccgcccggc tcggcgacgc gcccgtgctc
      241 ccgaccggcg ccggccacga cgccggggtg ctctccggcc acgtccccac cgcgatgctc
      301 ttcgtccgca acccgaccgg cgtctcccac gcccccggcg agcacgccac cgacgacgac
      361 tgcgccgccg gggtggtcgc gctcgccgac gtgctggcgg agctcgcatg ccagtgaccc
      421 cggcaggccg gccgcggccg gccaccaccg ccggcaccgg gacggggacg gggacggatc
      481 gatgaaccgg ttccacgcgg agctggcctg gctgggcgac cggccagcgc cggaggtgct
      541 gatcgaggtc gacagtggcc ggttcaccac cgtcgccccg gacacggccc agccggccga
      601 cgcccgccgc ctcccggggc tcacgctgcc cggcttcgcc aacacccatt cgcacgcctt
      661 ccaccgagca ctccgcgggc gtacccaggg cggcgccggc gacttctgga gctggcggga
      721 acgcatgtac tcggtcgccg accagctcga tccggctagc tacgcggccc tagcggccgc
      781 ggtctacggc gaaatggcgc tcgccgggat cacctgtgtg ggcgagtttc actacctgca
      841 tcaccagcgc gacggccggc cgtacgcgga ccccaacgag atggcgaccg cgctggtcga
      901 agcggcggag cgggccggga tccggctcac cctgctcgac acctgctacc tgaccgcgga
      961 cgtcgccggg gcgccgttga ccgggccgca gcgccgcttc ggcgacggtg acgccgacgc
     1021 ctgggcggcc cgggtggcgc ggctgcggcc ggcggggcac tggcaggtcg gcgccgcgat
     1081 ccactcggtg cgggcagtgc cggccgatca gctgccggtc gtcgccggct gggctgagca
     1141 ggcggcggcg ccgctgcatg tgcacctctc cgagcagccg gcggagaacg aagcctgcct
     1201 cgcccgctac ggcgtcacgc cgaccgccct gctcgccgac gccggggcgc tcggcccccg
     1261 ggccatcgcg gtacacgcca cccacctcac cagcgcggac cggcgactgc tcggggcagc
     1321 cggcgcggga gtgtgcttct gccccaccac cgaacgggac ctcgccgacg gcatcggccc
     1381 ggcccgcgcg ctggtcgacg cgggggcgcg gctcagcctc ggtaccgaca gccacgcgat
     1441 gatcgacatg ttcgaggagg ggcgggcggt cgaactcaac gcccggctgg ctgatcagcg
     1501 gcgtggccac ttccggccgg atgagctgat cgcggcggcg acggtcgccg gccaccaggc
     1561 gttaggctgg gaggacgccg gcgtgatcgc gccgggcgcc cgcgccgacc tggtgaccgt
     1621 cgcgctcgac agtgtgcgca ccgccgccac cgacccggcc gcggtgatct tcgccgccac
     1681 cgccgccgac gtgacccagg tggtcgtcga cggccggcag gtcgtggccg acggccggca
     1741 tcttgccatg gatgtgcccc gggcgctgga ggaggcgaca ccgtgagcct gctggtggac
     1801 aacatcggtg aactggtcac caacgacccg tcctacggcg acgacccgct gggcatcctg
     1861 cgggacgcgg cggtggtgat cgaggagcga cgagttgcgt ggctggggcc cggcgccgag
     1921 gcgcccgccg ccgacgaccg ggtcgacgcg gccggggccg cggtgctgcc gggcttcgtc
     1981 gacagccact cccatgtggt cttcgccggt gaccgggccg ccgagttcgc cgcccggatg
     2041 gccggcgaac cctacaccgg cggcggcatc ctcaccacgg tcgccgccac ccgggccgcc
     2101 tccgacgccg agctgcgcgc caccgccggc cggctgcggg ccgaggcgct gcgtcaaggg
     2161 accaccacgc tggaggtcaa gagcgggtac gggttgacca tcgccgatga gaccaggtcg
     2221 ctgcggatcg ccttcgaggt gacgccagag tcgaccttcc tcggtgccca tctggtgccg
     2281 cccgagtacg ccgaccggcc tgacgactat gtggagctgg tctgtggccc gatgttgacc
     2341 gccgccgagc cgtacgcccg ttgggtggat gtcttctgcg agcggggcgc cttcgacgcc
     2401 gaccagtccg aagcggtgct gcgggccggg atggcgctcg gcctggcgcc ccgggtccac
     2461 gccaaccagc tcggccccgg cgccggagtg cagctcgcgg tggcgctcgg cgccgccagc
     2521 gcagaccact gcacccatct atccgatcag gacatcgccg cactggccgg ttcggatacc
     2581 gtcgcgacgc tgctgccggg cgtggagttc tccacccgtt cgccgtaccc ggatgcgcgg
     2641 cggctactcg acgcgggcgc cactgtcgcg ttggcctccg actgcaaccc cgggtcgtcg
     2701 tacacctcat cgatgccgct gtgtatcgcg ctggcggtgc gggagatggg catgaccgcc
     2761 ggcgaggcgc tgtggtccgc caccgctggc ggcgcccggg ccctgcggcg cgacgatgtc
     2821 ggcaccgtcc ggttgggctc ccgggccgac ctggtgctgc tcgacgcgcc ctcctacctg
     2881 cacctcgcct accggccggg ggtgccgctc gtccgccaag tcatccacaa cggagtgttg
     2941 atgtgagcgt agttgagatt ctgccgaccg gcgtcagccc ggccgacgtg gtagcggtcg
     3001 cccgcggcga cgccacggtc gaactctccg ccgcggcgag cgccgcgatg accgacagcc
     3061 gcgccatcgt ggccgagatc gagcggcagg agcgcccggt ctacggggtg tcgaccggct
     3121 tcggcgcgct cgccaacacc ttcatcgacc cccaacgccg tactgagctg cagcacgcgc
     3181 tgctgcgctc gcacgccgcc ggcgtcggcg cccggatgcc caccgaggtg gtccgggcga
     3241 tgctgctgct gcgggtccgg tcgctggcga aagggctctc cggggtccga ccggtggtcg
     3301 ccgaacggct gatcgacctg ctcaaccacg gcattacccc gtgggtaccc gagcacgggt
     3361 cgctcggcgc ctccggcgac ctggcgccgc tggcccactg cgggctggtg ttgaccggcg
     3421 aaggctgggt cgtcggcaag gacggcgccc ggctacccgc cggccaggtg ctgggcgagg
     3481 ccgggctggc gccggtcgag ctcgccgcca aagaagggct ggcgctgatc aacggcaccg
     3541 acggcatgct cggcatgctg ttgctggccg ccgaggacgc cgcacatctg ttcaccatgg
     3601 cggatgtgac cgcagcgctg gcgatcgagg cgatgctcgg caccgaccgc ccgttccagc
     3661 cggagctgca cgccatccgg ccgcatccgg ggcagcgcga ctccgccggc aacctggccc
     3721 ggctgctgcg gagctcggcc atcatggact cccaccgcga cgatctggag cacgcggtgc
     3781 aggacgccta ctcgatgcgg tgcgcgccac aggtcgctgg cgccgcccgg gacacgctcg
     3841 cgttcgccgt gggcgtcgcc gaccgggaac tggccagtgt ggtcgacaac ccggtggtgc
     3901 tgccggacgg cagggtggag tccaccggca acttccacgg cgcgccgttg ggcttcgccg
     3961 ccgactatct ggcgatcgcc gccgccgaag tgggggcaat ctcggagcga cgggtcgacc
     4021 ggctgctcga cgtgacccgg tcccgcgggc taccgccgtt tctgactccc gaccccgggg
     4081 tcaactccgg tctgatgatc gcccagtaca ccgccgccgg cctggtggcg gagaaccggc
     4141 ggctggccgc gcccgcctca gtggactcgc tgcccacctc cgggatgcag gaggaccacg
     4201 tctcgatggg gtgggcggcg acggtgaagc tgcgcacggt gctggacaac ctcaccagcc
     4261 tgctcgcggt ggaactgctg gcggcggtcc gcgggttgca gctgcgggcc ccgctgaccc
     4321 cttccccggc cggtcaggcg gcgatcgccg cggtctcgga gtttttcggc gaaccgggcc
     4381 cggacgcttt cctggccccg gcgatggagt ccggccgcgc ggtgatcaag ggccgcgagc
     4441 tgcgcgccgc catcgaggca gccggtccgc cactcgcctg agcgtgcccg cccggatcac
     4501 cgtggccgcc gccaccgcgg tcgccaccgc cagggtgccg gcgccgagcg cgagccaacc
     4561 caagctgctg ccggagatcg gcgcggcgag atgggtggcg tcggtgtcgc agacgatcgg
     4621 ctcacccgcg gcctggtcga gcgcgcaggc ggtgaaggtg acccgttgcg gggtgccaac
     4681 caccggggcg gcgccgccgg ccgggtcggc ggcgctacgg ggggcggcgt agacgccgac
     4741 cagcctggtc gtctccaccc cacccggcgg gacgacgagc gaccactcga cgtacccgtt
     4801 gtctgcggtg gcgccggtcg gggtcagcca gggcgggacg ctcgcccgga cggtgaccgg
     4861 ctgcgcggcc tgcccccggt tcccgacggc gatcgtgtag gtggtctgct tacccgagcg
     4921 gacccgctcg cggtcccgct cgaccgcgat gaccagctcc tggacctcgg tcgcctcggt
     4981 gaagcgggcc cattcgtctt ccggctccga ggtcgcccac cagtagaccg cggtgcccag
     5041 gccgagcagc accgccagaa ccgccggcgt aaccgccgcc gccaccacga gtacgcgccg
     5101 catcgcccac cccccgccca gctgccccgg cactcatccc cgtaccgaat gatatgcccg
     5161 attcagggct tacaagagcg tttgtacgca gcgatggggg cgaagggtgc aagtgcgact
     5221 acggacggtt cagctacggg cggttcagct acgggcgcgc cgctcggcgc cggcggagcg
     5281 cgccgacgat gaaccagaca ccggcggccg cgacccccgc gatcacgcca ccgtaaacgg
     5341 aggtcgcgaa gccgagcacc aggcccatga ccaacccgat cgccactgct ccaccgagcc
     5401 agaacgtcgt gctctcacct tgcgaagcca tcgtggatca gtccctccgg agcgggccgg
     5461 cgcagcggcc agggaccgtg actctaccgc ggctaaccgc ctggccgagt cagctgccgt
     5521 cgatgaggac ccgggcgatg agcttgccca tcgcccggaa cgcctggccc cgatggctga
     5581 tcgcgtcctt ctccgccggg tcgagctcgg cgttggtgcg ggtctcgccg tccgcgacga
     5641 agatcgggtc gtacccgaaa ccgccaccac cccgcgggcc gcgggtcagc accccgggct
     5701 gccggccgtc caccagatgt tcccgaccac cgggcagcgc cagcgcggcc gcgcacacga
     5761 acgacgcctg ccggttcgcg tccggcacgt cggcgagctg cgccagcagc agttgcagat
     5821 tcgcctcgtc gtcgccgtgc cggccggccc agcgggcgct gaacaccccg ggagcgttgc
     5881 cgaacgcgtc caccaccagg ccggagtcgt cggcgatcgt cggcaggccg gtgtgccgga
     5941 gcccttcgcg ggccttcaac agcgcgttct cggcgaaggt caggccggtc tcgggcgcct
     6001 ctggatattc tgggacgtcg gcgaggccga ccagctccac actgcccacc ccggtgagga
     6061 ttcgccgtag ctcggtgagc ttgtgccggt tgcgggtggc gagcagcagc cggtgcgtcg
     6121 cggtcacgtc aggaccaccc gctgcgcctc ggacagctca gcgcagccgg cgaccgccaa
     6181 ctccagcatc gcgtccagct ccgaccggga gaagaccgac gcctccccgg tcccctgcac
     6241 ctcaacgaag tcaccgttgc tcgtacagac cacgttcatg tccacgtcgg ccgccacatc
     6301 ttcggcatag cacagatcta gccgcggctc accctccacc acgccgacgc tgaccgccgc
     6361 cactgaccgg tgcagcacca ccgacggggc cttccggagc cgctgccggt tggacagcca
     6421 cgacaccgcg tcggcgaggg cgacgtacgc cccggtgatc gccgcggtcc gggtgccccc
     6481 gtcggcctgc aacacgtcac agtcgagcac caccgagttt tcgccgagcg cgcccaggtc
     6541 gatgcaggcc cgcaggctgc gcccgatcag ccgggagatc tcgtgggtcc ggccgccgat
     6601 ccggcctttg acgctctccc ggtcgttgcg gctggtggtg gcgcgcggca gcatcgcata
     6661 ctccgcggtc acccacccct ggcccgaccc gcggcgccag cgggggacgc cctcggtcac
     6721 gctcgcggtg cacaacactc gggtgtcgcc gaactccacc agcaccgatc cctctgggtg
     6781 gctgctccat tcccgggtca accgcaccgg ccggagctgc tcgggcttcc gcccgtcagg
     6841 tcgcgtcatg cccgccacca tatgtcaggc cggcagcgtg gctcgctcct ggttcggcag
     6901 gcggggcggc gctggcgacc gccaccgccg ccgccaccgc ctcgggcagg ctggccaggc
     6961 tggtcacccc cgccggcaag ggctgtgacc agccgggccc ggcagccgcc accaccgctg
     7021 gccggggccg gctggcgatc agcgccacca gcggcgccgg gtcggcggta cgacgggcgt
     7081 gcgaccacac cacgaccagc cccggcccgg tacgccgggc ggcggccgcc agcgccggcg
     7141 ccggcaggcg ggcaccgagc agccaggcgt tgatctcccg ctgggccagc gccgcggcga
     7201 gcgcctccag cggcagcgag tgctgctcct cggcggcgca ggtgagcagc gcctgcggcg
     7261 gggtggccgg ccggggcacc gctccgagca cctcggagat gccccgggag agcaggtgct
     7321 ccaccgccac caggccgccg gccgacccgt gggggcccgc ctgtttcgcc tcgatccggc
     7381 ccagcgctgg gcggatcagc ccgtcccagg cggccgccgc gcccaggtcg gccacggcct
     7441 tcgacaccac ccggcggacc gagccgatgt ccagccgctc ggccgcgtag acgagcccgc
     7501 ggaccgccgc cgacgagacg gcctccggct cgtcggcggg gccgtggccc gggtgatccg
     7561 gcaacgcccg ggcggcggtg gcccgccccg agcctggtgc gggggcgccg gcgcgggcca
     7621 gccgggcggc ccgcgcggcc ggaaccccct gcgaggtcag cgtgcgcatc agctccaacc
     7681 tggccagatc gtcggcgctg tagcggcggt ggtggccggc ttcgtgctgg gtcggcccca
     7741 ggccgtatcg gtggtgccag ctacgcagcg tggtcaccgc cactcccagt cgccgcgcgg
     7801 cctcacccgc ggtgagtcca gtctcgatca tccaccccag tgtttaccgg ccacagtgtc
     7861 caacggtgcg gcgaccccgg ctagccacgg ggcgcacgcc gccggctgct gttcgagcag
     7921 ccggtgcagc tccaccgggg cgacccacca gagttcggcg acctcggccg ggtccggcgc
     7981 cagccgctgg tccaacggga tctgtccgac cagcacgtga tcgtactcgt actccaccca
     8041 gccgctcgcc gggtcggtgg cccgataccg gtagaccccg acctcgcgca gctcgacccc
     8101 ggtgacgccg agctcctcgg ccagccggtc ggtggccgcc gccaccaccg actgccccgg
     8161 ggcggggtgg ccgcagcagg agttggccca gcgcagcggg aaccgggtct tcaccgcggc
     8221 ccggcgttgc agcagcagcc gctggccgtc caacgccagc agcagcaccg agaacgcccg
     8281 atgcagctgc cccggggcgg tgtgggcccg cagcaccgta ctgctgccga tcgggtcgcc
     8341 gcccgagtcg accagctcga ccggcaacag cgcccggtcc aggtcaggga tcatcgggcc
     8401 gctccggtca cccgggcagc ggccagtttg ccggagatca gcaccatcgg cacgccgacg
     8461 cccggctgcg tcccggagcc cacgaagacc acgttgtcga gcgccgggtg gaggttgttc
     8521 ggccggaacg ggccggtctg ggcgaaggtg tgggccgccg cgaacggggt gccggcggcc
     8581 agcccctggt cggcccagtc ggccggggtg accgggtggc agaccgtggc ggcatcgcgg
     8641 aatccgtggt agccgcgggc ttcgagcacc tcgaagagct gcgacacgta cgcgtcggtg
     8701 agcccggagc gccacgcctg ggcgccggtg gccaggttcg gcgccggcgc gagcaggtag
     8761 tagctgtgct ggccggcggg ggccaactgg ggatcggtcc gggtcgggtt ggtgaccagc
     8821 agcgacgggt cgctcatcaa ccgcccttcg tcgatgacct cctggaaggt ccggcgccag
     8881 gcacgaccga agtggatgtt gtggtgggcg atcttcgagt agtgctgccg agagccgata
     8941 tggaccacca cgcaggaggg cgagtagcgc aggcggcggc gcagacccgg gcccggtagc
     9001 aactcatggg cggcgggcag gtcggggttg agcaccacca cgtcggcggg gatccgctcc
     9061 ccgccggtgg tgtggacggc gaccgcccgg ccggcgcggg tctccacccg ggtgaccgtg
     9121 gtgtcgtagc gcagctcgac gccgtgcttg tcggcggcgc cggcgagcgc ccggggcagg
     9181 gcgtgcaccc cgccgcgtgg aaagtagacc ccgcacaccg cgtccaggta ggcgatgacc
     9241 gcgtagatcg ccagcgcccg gtgcggcgcc aggccggcat acatcgcctg gaacgagaag
     9301 atccgccggg tgcgcgggtc ccggaagaac cggtcgatgt acgcctgcag ccggccgaac
     9361 ccgccgacgg cgagcagtcg cagcaggttg ccgttgagca ggtcggtcgg ggcgtcgagg
     9421 ttgcgggcga tgaagtcgtc ccgctccagc tgccacagct gccgggcact ggccacgaac
     9481 cgccggtagc cggcggcttc ccgcgggccg cagacctcgg cgagctgctg cgccatccgc
     9541 tccggatcgg tgatcacgtc tagcgaggag ccgtccggga accaggcccg gtacgccggg
     9601 tcgagggtgg tcagcggtag ccagtcggtg agcgactcgc cgaccgccgc gagcggctcg
     9661 gcgatcaggt cgggcatggt gagcacggtc ggcccggtgt cgaattcgaa cccggccagg
     9721 gccagccgac cggcccggcc gcccggctcg gccgcccgct ccaccacagt cacctgccgg
     9781 ccggcgccgg ccaggtgcag tgcgcaggcc aggccaccga gcccggcgcc caccacgacc
     9841 acccgctcgg tggctcccgt gacctggcgc atcagctccc ccactcccca cggtgcgcgg
     9901 cggtccacgt cgaatccccg ccccgcggta cccggttagg atagcctggt gcggtaagtt
     9961 gcgtcgattg ttgcatcgtt ttgcgagggg gttggtgatc gtggagccag cgctcgccgc
    10021 cgcttaccag cggtgccggc agctgcatcg acaccacggg cggacgtact acctggccac
    10081 tcgcctgctg cccaggcaca agcgaccaca tgtccacgct ttatatggtt ttacccgata
    10141 tgccgatgag atcgtggaca gaaccgaaga tctccccccg gataagcggg ccgaacggtt
    10201 ccgggagtgg tcggagacct tcctcgccgg cctcgccggt gcaccggtca ccgatccgct
    10261 gctgcccgcg gtgctgcaca cgatcgacgc ctgccagctc gaccccgacg acttcgccgc
    10321 cttcctcaag agcatggcga tggacctcac ggtcaccgag taccagacct acgaggagct
    10381 gctctcctac atggagggtt ccgcggcggt gatcggcacg atgatgctgc ccatcctcga
    10441 cccgaccgac ccggcagccg cccgcggacc cgcccgcgag ctggggttgg cgttccagct
    10501 caccaacttc atccgggatg tcggcgagga cctcgaccgg ggccgcatct acctgccgca
    10561 gcaggacctg gcccggttcg gggtcacccc cgccgggctg cgggccgctg ccgcgcgcgg
    10621 cagcgccgat cccgcgatcc ggtcgctgat ccgctatcag gtgacccggg cacaccagca
    10681 ctacgccgcc gccgcacccg gcgtcaccat gctcacgccc agctcacagg cgtgcatccg
    10741 ggccgcctat cacctgtacg cggagatcct caccgaggtc gcccgggtcg acttcgacgt
    10801 attccgccgc cgcgcggtgg taccgcgtgc ccggcgggcg cggctggccg cccgtagcct
    10861 gctcacccga gccgggaccc cggtcacccc acccggcgcc cggaggccgg catgacccgg
    10921 gaggccacgc ccgccgtgct gctgttcacc cgcgatctac ggctcgacga caatccggcg
    10981 ctcgccgccg ccgcccgcgg gccggtgctc ccgctgttcg tggtggaccc ccggctaccc
    11041 gccggcgaaa accggcgcca cttcctcgcc gagtgcctga ccgacctgcg ggagtcgctc
    11101 cggcagcgcg gcgccgacct gctggtccgg cgaggtgacc cggttcacga agcgatctcg
    11161 ctcgcgaaac agatcggcgc gggcgccatc catctcgccg aggatgtcag cggctacgcc
    11221 acccgccggc agcggcggct cctgacggcg gccgactccg cccggctcac cgtccacctg
    11281 catccgggca tcaccgtggt gcccgcgggc gacctggtgc cggccagcgg cgaccactac
    11341 cgggtcttca cgccttactt ccgagcctgg cgacagatcc gctggcggga tccagcggcc
    11401 gcaccggcgg cgctgtcgct gccacccggc gccgctgacc tccctcgcca ggaaccagcc
    11461 gccgcgctgg gccggatccg cgcgaccgcc cggaccctgc ccaccggcgg cgagtcggcg
    11521 gcggaggccg cgtttcggca gttcggtcgc tacgccgccg agtaccccga gcggcaggac
    11581 gacctcgccg ccgaccgcac ctcccggttc agcgcgtacc tccacttcgg ggcgctgtcg
    11641 gcgcgccgag tggcgacctc gccggccatg cccgaggcgc tggtccgcca gttctgctgg
    11701 cgcgacttcc accaccaggt gctggcggcc tttccggcgc tgccctggga gccgtaccgg
    11761 cggcgcgcgg acacccccga cggcgtggac cgcggcggcg ccgcccccgc cgacgccgac
    11821 accctggcgc agtggcggga gggcagcacc gggctgccga tcgtggacgc cgggatgcgg
    11881 cagctgcagg ccgaggggtt cctccccaac cgggcccggc tgatcaccgc cacctacctg
    11941 gtgaagcggc tgcggggcga ctggcgcgac ggcgccgcct ggtacgacga ccagctggtc
    12001 gacgccgacc tggccaacaa ctacggcaac tggcagtggg tcgccggcac cggcaacgac
    12061 acccggccgc accgaggttt caacccgctc cggcaggcgt cccggttcga cccggcgggt
    12121 gagtacgtgc gccggtggct gcccgaactg gccgaggtga ccggcccgca ggtgcatgaa
    12181 ccgtggcggc tgccggagcc ggtacgccgc gggctgcgct acccgatgct cgaccctgcg
    12241 accctcgacc ccgcgacccc ccggagccgc tgatggaccg ctggcactac gtgttgattc
    12301 tcgccgcctg tctgctgatc actctgccgc tggagctgct gccgggggtg cgggtgtacc
    12361 ggcggccgaa gctgctgctc gccagcatcg ccccggttct ggtgatcttc gtcggctggg
    12421 acctgctcgc ctaccaccac ggccactggt ggttctccga ccagtacacc ctcggccccc
    12481 ggctggccgg cctaccgctg gaagagtggc tcttcttcgt cgtcgtgccg ctgtgcgcgc
    12541 tgctgaccta cgaggcggtc ggctcggtgc tggcgcgcgg gcgaggggcg gccgcccgcc
    12601 gggccaccgc cgccccgacc accgccggag gttcggatgc ctgacctgcc gctgtacacc
    12661 gtcgccgcgg tggcggcgcc gctgctggtg gtggcgctgg agctgctggt gctgcgcacc
    12721 ggcctgttcc ggaccctgcg ctactggctg accatgctga tcgtgctcgg gttccagatc
    12781 ccggtcgacg gctggctgac caagccgcag ggcacggtgg tgctctacga cgaggcgcag
    12841 atcctcggca tccgggcgcc ggtgtcgttc ccgatcgaag atttcgggtt cggcttcgcg
    12901 atggtgaccc tgaccgtgct gctgtggcgc tggctgcgca atcgtgagca acgccggccg
    12961 gccccgcccg cggcggccca gcagtcgccg gcccggaccg cggagcaggc aagtgcgtga
    13021 gcggagcccg accgccagcg cgatgttcca gggcttccgg tggctggtcc ggcagagcct
    13081 gcgcggcgtg tggtggcgcg gcgacccgcc cgccgggccg ttcgtctggg ccgccaacca
    13141 ccacagctgg tgggatccgt tcatagccgc cgcgttgctg gaacggtggc gacgggtcgg
    13201 gtgcctcctg ctctcccaga ccaatctgga gcgctaccgg ttcatcgaac ggctcggcgg
    13261 tttcggcacc ggcgagtacc ggcgcgggtt gtcctatcta cgcgccggcc gggtgctgat
    13321 catcttcccc gagggggagc tgcggccgcc cgggccgctg ggccggttgg ccggcggcgc
    13381 cggctggttc gctcacaccg ccaaggttcc gctctacgcc gtcgccaccc gggtggtggt
    13441 gcgcggccag caggccccgg aggcgtacct gtcgctggcg caggtcgcgc cgccgaccgg
    13501 gctggcctcc cgcgacgccg cccgggagct gaccggccgg ctgaccacga cgctcaccga
    13561 cgagctggcc gccctcgacg cggcagtggc cagtgcggac ccgcggcagc cgctgcccgg
    13621 cttcacccgc gcggtggcgg gccggcgcag ttgggacgag cggatcgacc gagtccaccg
    13681 gtggttgccg tggcgcccgg agcggtgact cggatgggcg gcgccctgcc cgcgctggtc
    13741 gccggcttcc acctgaccaa gaccgtcggg ttgctggaca atctggccag tttcccggtc
    13801 ctcggccggc gcccgagcgc cgccccaccg ctgccgcggg tttcgttgct ggtcccggcc
    13861 cgcgacgagg ccgaccggct gccgcggtgc ctgcctggcc tgctggccca gcccgccgcc
    13921 gaggtgctgg tctgcgacga cgagtccacc gacgacaccg ccggggtggt ccgccgcgcc
    13981 gccgctgacg acccccggct gcggctggtg ccgggcaccc cgcgcccgcc cggctggatc
    14041 ggcaagagct gggcctgcca ccagctcgcc gccgcggcca ccggcgacct gctggtcttc
    14101 tgcgacgccg acgtgctgct ccaaccggga gcgctcgccg cgctgtgggc ggagctgacc
    14161 cgccagcgca gcgaggtctt ctcggtcttc ccccggcagc agaccgggac gctcggcgag
    14221 cggctgctgg tgccgctgat cgacgaggtg ctgctcagct tcctgccgca ccggttgttg
    14281 tcgctgccgg tgcccgccgc cgccaccgcc aacggtcagc tgctcgcctt ccgccgttcg
    14341 gcgtaccagg cgatcggcgg gcaccgcgcg gtggcggacc ggatcgtgga agatctggcg
    14401 ttggggcggc tggcgcggcg acgcggcctc cggctgggcc tggcgctcgg cggcgacctg
    14461 gtcagcgccc ggatgtacga cgggtacccg cagaccgtac gcgggctggg gaagagcatg
    14521 cgcgaggcgc acggtgaccg ggacgcgttg ctactggcga gcctgggctg gcacctgctc
    14581 gcctacacgg tcccgtggct gcggtggcgg tccgcgcccg gctggcggct cgccgcgact
    14641 ctcagcgtcg cccaacggct gttggtcaac gccaagaccg ggcggggcag cccgtgggag
    14701 gcgctgctgg tgccggtgac cgccccggcg gcgatcccgg tctacctgct ggcggcccga
    14761 cgccgggcgc gttggcgggg acggagctac ccgtgacggc gccgaccctg cggagcccgg
    14821 cgcggttgcc gcagccgccg gggcatccgg tcatcggcca cctgtggccg tggaccttcg
    14881 ccccggtgcc gctgttagcg gcgggcgccc gcaccggcga ggtgttccgg ctacggttgt
    14941 ggcggtcgac gctggtcggc taccgtccag agtggaaccg ggcagtcctc ggcgacctgg
    15001 acacgttccg cagccggggc agtctcagcg gcctgacgcc gtacctcgcc gacggcgtgg
    15061 tccacaccga cctgccggcg cacgccccgc accggcgggc cctcaacccg catttccaca
    15121 gccaggcggt gcggcagctc accgatcggc tgcgggccgc cgtccagtca gggttgccgg
    15181 ggcgctactt cgacgcgttg ccgtgggccg gcagcgtggt ccgccggatg ctctccgccg
    15241 cgctcttcgg cgaccgcatc ccgcaatcgt tactcgagcg cttcctggcc ccgctgcacc
    15301 ggcccaaccc ggcgccgctg ctgccccggc caaggctgtt ccggcggatg aacacggcga
    15361 tcgccgcggt ggtcgccgac cccgtgccgg gcacgctcgc cgccgcggtg gcgggagagg
    15421 cggccgccgg cggtgacctg gacccggtcg ccgagctgcg ggtggcgctc gccgccggct
    15481 acgacaccac cgcgcacacg ctggcgtgga cactgtggtg gctggccggt tcgccggcgt
    15541 ggcgggatcc ggagtcactg ccgatggtgc tcgacgagat cctgcggctc tatccggccg
    15601 ggtggttggg cagtcgggtc gcggcccggg acacggaggt ctgcggggtg gcgatccccg
    15661 ccggcaccat ggtctgctac tcgccctacc tcacccaccg ggatccgggc ctgtggccgg
    15721 agcccgacca gttccggccc gaccggttca ccgccggccg gccggcctgg ggtttcatcc
    15781 cgttcgccgc cggccggcgc acctgcctgg gcgcccagct ggcgcgggcc atgctgacct
    15841 gcgccagtga gccgttcctc gccgggccgc tgcgacagct caacggcgac ccgtcggtgg
    15901 tcgccgggat caccctgcgg ccgcacggtc cgctgtggct gtcctggcgg ggcgagtaac
    15961 tggccggccg gcgcctgacc ccgcctggga caatgcgagt acggttccac cgtgtcctgg
    16021 ttacccctgc cgttgatccg gcgctgccaa cgcctggcgt accgcttctg gtgccggctg
    16081 caacgccgtc acgggtcggt gcgccggctg gtccgggccg gtaagcgcta ccggcaggcc
    16141 gacgggcggc ggctcgcggc cgcggtcagc tactacggct tcttcgcgac cttcgcgatg
    16201 gtgctgctgg gcttcgccgc actcggatac gtggtcgacg atcccggcgt gcagggggcg
    16261 gtgcagcggt tcctggacga gaacctgccc cgggtggaca ccgacgcggt ccgcgacgcc
    16321 cgggaggcga ccggcctgat cgccttcgcc agtctgctgg tgatcggcct gttgtgggtg
    16381 gactcgctgc gctcgtcggt gcgggcgatc tggcggatcg aggagtaccc gggcggattc
    16441 ttccgtcgct ggttcatcga cgggctggcg ctggtggggc tggggaccct gctggcggtc
    16501 tcgctcaccg tcgcgctcgg cgccgaggcg ctgctgggct ggctggtgga gctgatccgg
    16561 gccggcgagt tggcgccggc ggagtggctg ctgctggtgg tccggttcgg gctgaacttc
    16621 agcgtcaaca ccatcctggc gatcgcggcg ctgacgctgc tgccacggct gcggatgccg
    16681 ctgcgtcggg tgctcccgcc ggcgctgctg gtcgccgcgg gcgcggagtt cctgacctcg
    16741 gtggggcggc tggtggtgga ccgggccgag tacaacccgg cgttccaggt ggtggccggc
    16801 gccgccgggc tgctggtgtt cctgctgatc ctgaaccagt tgatcttgtt tgcggcgtcg
    16861 ctcaccgcga ccgcggagca gggccgggtc gtcgacctgg cgcgccgcaa cgggttgcgg
    16921 ggcagctact acgcgtcctg atcgatcatc cggggcgccg cggcgagcgc ccagatgacg
    16981 aagatggcca gcgcgatcac caccagcgac cagagcgggt agtagggcaa gaagaagaag
    17041 ttcgcgaccg ccaccacgat ggccagcgcg atgccgacca cccgcgccca catcgcgccg
    17101 gtgaagatcg cgaggccgac caggaagacc accacgccga tgccgagatg gatccagccc
    17161 cacgtggtca cgtcgatctc gtaggcatac tccgggctga ccacgaagaa gtcctccgca
    17221 gcgagcgccg cgatgcccat cagcgcctgc cagaagccga tgatcagcat cacggtggcg
    17281 ccgaagacca gaccaccgat cgcccagccg cgggcccgct gactctgcgg tgcgctcgcg
    17341 tgcgccatga cgaaccccct cggatcggtc acctcccctg agcgtacgcg agagtagtcc
    17401 gcttttgaga cggtttgccg ggaaggtcga tcccgatcgc ctcgtagtag tggtccagca
    17461 gcaggtcgcc gatcgccgac cagctccgcc cggcgaccga ttcccgcgcc gcccgggcgt
    17521 atgcgtcccg acgccccgga tcggcccgca gccccgccac caccgccgcg atcgcaccag
    17581 catccgccgg cggcaccaac gcgccggtca gccccggcgt caccagatcc atcggaccgc
    17641 cggccgccgg cgccaccacc ggcaccccac tcgccagcgc ctcctgcacc gtctgcccga
    17701 acgtctcatg cggacccgta tgcgcgaaca cgtccaggct ggcgtagatc cgcgccagct
    17761 ggtggccgtg ccgctccccg aggaagaccg ccccgggcag cgcccgcgcc aacgccggcc
    17821 ggctcggacc gtcccccacg accaccaccc gcacccccgg cagccggcat accgcaccga
    17881 gcagctccac ccgcttctcc ggggcgagcc gcccgacgta ccccaccagc aactcgccgc
    17941 ccggcgccag cagccgccgc agccgctcgc tgcgccgcgc cggggagaac cggtcgaggt
    18001 cgaccccgcg tggccacagc cgcacccgct cgatgccctg agccgacagc gccgccgccg
    18061 cagccttgga cggagccagg gtcagatcgg cggtgttgtg gatccgccgc agccagcgcc
    18121 acgccagaat ctccgcgggc gcccgccgcc ccgccaacat ctccgcgggc gcgcgccgcc
    18181 accggcccgg cccgtagagc cgcaggtacg cagccatgtc ggtctggtag accgccaccg
    18241 tgggcaggcc cagcgacgcc gcgagaccac ccccgcgggc cccgagcaca aacgggctcg
    18301 ccaggtgcac cacatccggg gcgtgggcga tcagcgcgtc ggtgagcgcc ggccccggca
    18361 ccccgatccg gaacccgcgg tagcccgggg tgggcacact cggcacccgc accaccgggt
    18421 acggacgcgg gccggccacc cgccgccggg tcgatgccgg agccggggcg atcaccagcg
    18481 gctggtgccc ggcgcggtac aggtggtcgg cgacccggcc gacggagttc gccaccccgt
    18541 tgacgtccgg cgcgaaagac tcggtgatca gcgcgatccg catgtgacca cggtgcgccc
    18601 ggcaacggag gaccgggcgt cgcgcggctg accggtcgac gaacggtagc cgaagagtgc
    18661 gtcgcgcggc ggccgtcggg cgacgaccag ccggcagagt cagccgatct cgtaccgggc
    18721 gcccggccgg acgatctcca ccgggcccgg gtacgcggcg ctcgccgcct cgaaggtggc
    18781 cgcctcgcta ccccacgcgg tgaccagatg ggtcagcagc agccggccca ccccggcctt
    18841 gctcgccacc tccccggcct cgccgccggt caggtgcaga tccggcgggt gcggcacgtc
    18901 gtcgaggtag ctcgcctcac acaggaacag gtcggcgccc tgcgccagcc gcagcagcga
    18961 atcgcacttg gcggtgtcgg ccgagtaggt cagcgtcccc ccgccgtgct ccagccgcac
    19021 cccgtacgtc tccaccggat ggttgacctg atcgacggtg accgtgaacg ggccgagcgg
    19081 gaaggtgccc ggctgcagcc cgtagaaggt gtagacatcg tcgagcgggg tcgcctccgg
    19141 cgtgtacgcc gcggcgagcc ggtccggggc gccagctggc gcatacaccg ggatcggcgg
    19201 gtacggaccg cccggggcgt agcggcggac caccacgtac gaacaggcgt ccagcacatg
    19261 gtcacagtgc aggtgggtga gcaggatcgc gtccaccgac atcagcccga tgtagcgctg
    19321 cagcgcgctg agcgacccgg tgccgaagtc cagcagcagc cggaacccct ccgcctccac
    19381 caggtaagca gagcaggccg actccggccc ggggaagctg ccggcgcagc ccaacaccgt
    19441 caacctcatt cggccacccc cgcgaactcg ggcgcggtca gctccatcag ctccgcgccg
    19501 aggaatcgct gcgccaaccg gcgaaacacc gcggcgtcgc cggtggtccg cagttgatgt
    19561 cgcggcggcg gcgaatccgc ggcccgcaac gacccggtct gcgtcagcac ccggtagaca
    19621 tcacgtgcgg tctcgtccgc gctggagacc aacgtcaccg actcccccat caccagcccg
    19681 atcatgcccg ccagcagcgg atagtgggtg caacccagca ccagcgtgtc gacctgcgcc
    19741 cgttgcaacg gctccaggta ggcgctcgcc aacccgagca gggtccgacc ggtggtggtg
    19801 ccccgctcga caaagtcgac gaactgcgga cacgccgccg tggtcacccg cacctgcggg
    19861 gcggcggcga acgcgtcctg gtaggcgccg ctgctgatgg tcgcctgggt gccgatcacc
    19921 ccgacccgac cgttccgggt cgccgcgacc gcccggcgca ccgccggtcg gatcacctcc
    19981 accaccggca cctgatagcg ctcgcgggcg tcgtgcaggc tggcggcggt ggcggcgttg
    20041 caggcgatga ccaacgcctt caccccgctg gcagcgagcg tgtccaaccc ggcgagcgcg
    20101 tgccggcgta cctcggcgat cggtttcggc ccgtaaggca cgtgggccgt gtcggccaga
    20161 tagcgcagct gctccatcgg cagctggtcg aggatcgccc gggcgacggt caacccgccg
    20221 accccggaat cgaagacccc gatcggcgcc tcctgatttg gagacaccgc cccatctgga
    20281 gacgctgccc cgcccggacc cccgctccgg gctgcaccgc tgctcgccgg ctccgcctgc
    20341 accagcgcag cctacgccgg atctcggcgg tcagcaggca cccgcctcga gaatgtcgcg
    20401 aacatgacac gtccccccgg ccgttactgc ttttggagta ggccgttacg gatagtgagt
    20461 tttgtccgat cgaacaccca aggacccata cgtgcgcacc acgacggtag cccggccgcg
    20521 ccgccggcga ccgcgcccca ccacccgagc cccccgagca gtcgccgccg caccacaccc
    20581 ggcgccgcca gccaccgacc gcggcgccgc cgcacagacc gaccccagca ccgaccagcc
    20641 aaccgccgcg gccaagcccg ctgcccgccg ccgactcatc cgcggcgcgg ggtggctcca
    20701 gccactgctc gccgcgctcc gacccgcagc gcaccagctg ggctggcaca ccggccggct
    20761 cgggcacgcc gcccggtacc gggcaaccgc gtggagcaac cggatggccc gcgcctggca
    20821 ccggcgcacc gccagcgacc gaaccctcgg ccggccaccg ctcggccggc tcctcgccag
    20881 tgaactgagc cgccggctcc ccagctggct ccgcccccgc gacccgacgc tcgccggggt
    20941 ccgcgacacg ccaccgccac ccgggcgcct cgccggcatg tgcacctggg ccgcgctgct
    21001 cggactgctg gggttgcccc tggccggcag ggcgttgctg accgtcgccg ccgggtcccg
    21061 gcccgactgg tcggacccgg gcatgctcac cggggtgctc gggatcggac tggcggtggc
    21121 tgctttcctg gtcgcccacc ggcgacgcgc cccctggctg ctactcggcc tcgccaccct
    21181 cctcctcgcc gccggccccc gactcttcgg cggagagtaa cccgaccacc cggcccaaaa
    21241 ctctgctcgg ctgacaacca cctggccggg ccgtcgcgtc ctgtaagaga ccaggggtag
    21301 ggacgacggc ggccggggcg gtgcacaccg cccgggccgc ttgccgacac gcggcgggcg
    21361 ggggcgccgg ggagggacca gaccgggatg cgactgctca ccttgacccc gtggcggcgg
    21421 gggccgctgc tgctgctgcg ccgaccgggc gtcgcggtcg ccctcttcgc cgccgcgatg
    21481 gtcgcggcgc tgcccgccgc agccgccccg atcttcctct cctccgccga gcacgccacc
    21541 ctgcatcggc agatcgacca gacctgcccg ggcttcgtcg gcgtccaggt caccggcgag
    21601 ctggcacccg tcggccagca gggcagcctc gacgcggtcc tcggcgaaga ccggttccgg
    21661 ggacgggaag cagcggtggc cgcgcacgcg ccggccggct tcgacccacc cgtcaacacc
    21721 gggtacggcg aggtcgacgt cgagttgacc gaccggccgc tacccaaccc ggacctttcc
    21781 gggctgctgc tgctggcccg cgacgacttc gccgaccaca tcgaggtagt cgacggcgcc
    21841 gccagccccg ccgagcagga cggcctgtgg ctgcccgacg agtacgccga ggcgcaacag
    21901 atccagatcg gcgacgagct ggagctggcg gcccgcggcg ccgacctcgg cagctggcac
    21961 acgtacgagc aggacgagca ggggctgctc ccgctgcccg aggtcgggag cgtcaccttg
    22021 ccggtggccg gcatctaccg cgacctccgg gcgtcccccg acccgccgta ctggtgcggc
    22081 gtcgcccagg tctaccgcgg cagcgaggac ccgttcgacg acaacctccc gccaccggcg
    22141 gcgatggtca cgccagagac gctgctggcg gtcggcgacg ccacccagct gcgcgccggc
    22201 caacagcttg agctgaccct caccgacccg gacctgacct caccggccgc cgccgaggtc
    22261 gccgaaggcg ccgccgcgct ccaggccacg ctctactccg aatatcggga cctcttcccg
    22321 aacaccttcc tcgacgaggt caccttctcc tccagactgg accgcttcca gcaacgggcg
    22381 gagctggtcc gctccgggat cgtcccgccg gtgctcccga tcaccgccgc cggcaccctg
    22441 gtcggcctgg cggtcaccgg cgccgccgcc ttctactggg cccagcgacg ccgccgcgag
    22501 ttggcggtgc tggccgccca cggcgtcagc gccagcgcga tcggggcgaa ggcggtattc
    22561 gaggcgctcc cggcgctgct gctgggcacc gtcaccggtt ggctgaccgc ctgggggctg
    22621 gtcgcgtcgg tcggcccctc cccggtgctc gcccaaggca ccctcgccac cgccgccctc
    22681 gccgccggtg tcaccggcac catcggtgtg ctgctggtcg ggctgctcgc cgccggccgc
    22741 gcccggggcc tggtcgacac gcccccggcc agccgacggg tcggctggtg gcgcaagctc
    22801 ccatgggagc tgaccctgtt cggcggcgcc gccgccagct ggttcatctt cgccgacgac
    22861 caggtctccg acacggtcgt cggcggggtc ggctcggtcg cccacatccc cgccggcctg
    22921 ctcctcaccc cgatcctgat catcatcgcg atcaccatcc tcggcgcccg gatcgccgcc
    22981 gccctgctcc gccggccggg gcccgaccgc cccgcccgcg
//
