LOCUS       NZ_CP070499            22724 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Natronosporangium hydrolyticum strain DSM 106523 chromosome,
            complete genome.
ACCESSION   NZ_CP070499
VERSION     NZ_CP070499.1
KEYWORDS    RefSeq.
SOURCE      Natronosporangium hydrolyticum
  ORGANISM  Natronosporangium hydrolyticum
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Natronosporangium.
REFERENCE   1  (bases 1 to 5699854)
  AUTHORS   Sorokin,D.Y., Khijniak,T.V., Zakharycheva,A.P., Boueva,O.V.,
            Ariskina,E.V., Hahnke,R.L., Bunk,B., Sproer,C., Schumann,P.,
            Evtushenko,L.I. and Kublanov,I.V.
  TITLE     Natrosporangium hydrolyticum gen. nov., sp. nov, a haloalkaliphilic
            actinobacterium from a soda solonchak soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5699854)
  AUTHORS   Sorokin,D.Y., Khijniak,T.V., Zakharycheva,A.P., Boueva,O.V.,
            Ariskina,E.V., Hahnke,R.L., Bunk,B., Sproer,C., Schumann,P.,
            Evtushenko,L.I. and Kublanov,I.V.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-FEB-2021) Bioinformatics, Leibniz Institute DSMZ,
            Inhoffenstr. 7B, Braunschweig 38124, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-MAY-2020
            Assembly Method                   :: HGAP v. 4
            Assembly Name                     :: 999_Micromonospora_sp_DSM106523
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 580.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016925615.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 06:45:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,188
            CDSs (total)                      :: 5,131
            Genes (coding)                    :: 5,046
            CDSs (with protein)               :: 5,046
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 85
            CDSs (without protein)            :: 85
            Pseudo Genes (ambiguous residues) :: 0 of 85
            Pseudo Genes (frameshifted)       :: 18 of 85
            Pseudo Genes (incomplete)         :: 72 of 85
            Pseudo Genes (internal stop)      :: 4 of 85
            Pseudo Genes (multiple problems)  :: 8 of 85
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:11:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2324536
            Orig. end                         :: 2347260
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070499.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22724
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="10"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22724
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22724
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12724](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12724)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            complement(947..2056)
                     /locus_tag="JQS43_RS10330"
                     /old_locus_tag="JQS43_10280"
     CDS             complement(947..2056)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016994.4"
                     /locus_tag="JQS43_RS10330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10280"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_239678847.1"
                     /transl_table=11
                     /translation="MTTQPTRTADLITNLAEHATVVGLGTSTREAHELFRQVEATTLRL
                     VERGFRTIAILDNQRVGELYDQYLGGADLDLDSVLAQAWGPWQVVEMRQTLTALREHNR
                     RHPNDPVRLLGIEGPRALPADYDRVLELLDGIDPPAAAAARGPLEVIRRAHSTGEHVLR
                     ALGTHPGTPFVELARAGREATAALPDGAERDEAVRLLDLIVEFHADAIGVGYDQDRAEQ
                     AAATRLLAHHQASGDRIVLWEGSAHVAAHGGPTLGSYLRQALGDQYVAVHLTFGAGRTP
                     RHEIPPARAGSLEGTLTAGGGERVVDLRAAAAADPPVALDRRWQIRLISGRYDPARDDD
                     HYYEFPSLADSFDAIAFTPTITPVEPLEL"
     gene            2322..2927
                     /locus_tag="JQS43_RS10335"
                     /old_locus_tag="JQS43_10285"
     CDS             2322..2927
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015325.4"
                     /locus_tag="JQS43_RS10335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10285"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_239678848.1"
                     /transl_table=11
                     /translation="MTTSTSHLAGPATVATPQIAVISASVRADRMCPSIADWVVGALTP
                     DATVDLIDLAEVTLPDDSLLYPGGGPKSEVAGRIEAAEAFVFVTPEYNHSYPASLKRLI
                     DWHYSEWELKPATIVGYGVYGGHSAIEHLRGVLAELSVVTTRRVLGLSQPWEHLSEDGG
                     YTPDEGAARGLAATVAELIWWAEVLTDARTNRPRPGQS"
     gene            3045..4112
                     /locus_tag="JQS43_RS10340"
                     /old_locus_tag="JQS43_10290"
     CDS             3045..4112
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /locus_tag="JQS43_RS10340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10290"
                     /product="IS30 family transposase"
                     /protein_id="WP_239678849.1"
                     /transl_table=11
                     /translation="MARAHVLTLGHRQVIENLWRQGSTFERIAAALGVGFSSVWREIAR
                     SHSSRHGTKNPLGPVRGGLYRWGYTAQWAQRHAEKRRARPKPRRLDHKPLREQVATWLR
                     QRWSPQQITHSLRRTFTGMPQMQVSHETIYKSIYLQARGSLRELVNDALRTGRKQRRSQ
                     SRAAQAARGAIRGKPWVTEQVHISARPAEANDRAVPGHWEGDLVLGRNNASAMVTLVER
                     TTRFVMLGALPVDRSSPEVLTVVRGLMARLPQHLVRSLTWDQGSELAGHASFTLATGCP
                     VFLCDPHSPWQRGTNENTNRLLRQYYPRGKTNFSVVSQAEMDTVAVSLNGRPRETLGWD
                     TPAEALNQLLLAPTA"
     misc_feature    4153..4167
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            4230..5483
                     /locus_tag="JQS43_RS10345"
                     /old_locus_tag="JQS43_10295"
     CDS             4230..5483
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020514319.1"
                     /locus_tag="JQS43_RS10345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10295"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_239678850.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.9e-54, bitscore:
                     182.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADEPRAGGLTIVDVAVFDGVSGELTDGPVHISDGVITAVGGRPH
                     PADQVIDARGGTVIPGLIDAHFHAYGVGLDLFRLEATPRSYVALAGARRLSAALSRGFT
                     TVRDVAGGDPGLARAIDEGLVASPRYLYTGPGLSQTGGHGDGRPGDLELCACGGQLAEV
                     VDGVDNLRRAVRDRFRRGAHAIKIMASGGVVSPTDPLRIPQYSPEEIRAVADEAGRRGS
                     YVAAHAYSPEAIVAAVRNGVRTIEHGNLLDADAARSMAEHGAYLVPTLVTYDAMDRRGR
                     EFGLAPVSQQKNREVLDAGRQAITLARAAGVPVGFGTDLMGPLEDEQLAGLRLQVEVDG
                     VVAVLQSATAVNAEVLGRPDLGRVQVGAVADLVILDGDPLADPSVLWAGADRRTVIQAG
                     RVVSPGRLGAASERGSTP"
     gene            5480..5845
                     /locus_tag="JQS43_RS10350"
                     /old_locus_tag="JQS43_10300"
     CDS             5480..5845
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019473.4"
                     /locus_tag="JQS43_RS10350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10300"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_239678851.1"
                     /transl_table=11
                     /translation="MSDPIGTPPGPPERPVEVARAFLDALAARDAATAASFLAPDVTFE
                     GPQSRLQGREAVLEELRQFAETVTAVTVIAALGDEAEAMLLYDVDAGEIGRLRVADHFA
                     VHDGRITANTAVFAALD"
     gene            5963..6520
                     /locus_tag="JQS43_RS10355"
                     /old_locus_tag="JQS43_10305"
     CDS             5963..6520
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020520769.1"
                     /locus_tag="JQS43_RS10355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10305"
                     /product="DinB family protein"
                     /protein_id="WP_239678852.1"
                     /transl_table=11
                     /translation="MTIIPDRKNWTWVLERACPECGFAAQSIPREQIPARLRACADQWR
                     LVLSGVVMTGGAATAEAVRQRPRPDVWSPLEYGCHVRDVCRRFSDRLAQLLAEEAPVFA
                     DWDQDAAAVAGRYAEQEPARVAAELVAAAARLADGFEAVTGEQWRRTGSRSDGAQFTVE
                     SLGRYFLHDPVHHLHDVGVLRR"
     gene            complement(6441..7931)
                     /locus_tag="JQS43_RS10360"
                     /old_locus_tag="JQS43_10310"
     CDS             complement(6441..7931)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013714.4"
                     /locus_tag="JQS43_RS10360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10310"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_239678853.1"
                     /transl_table=11
                     /translation="MATTAPGWRELATTLDGSLVRPDDTEFSSLRRPFVGGLTEVLPQA
                     VVRCAGAPDVARAVTFARKHRLPVAIRSGGHSFADHCATDGLLIDLGRLDTVALAGETA
                     TIGPGVRLGPLAQRLAVQGRIVSCGWNPLVAVGGAVLGGGFGVLSRRFGLGCDQLLAAQ
                     VVLADGDIVWVDEQREPDLFWALRGAGWAGFGVVTALVLRTFPVQRMCRFVHRWPWADA
                     AALIDAWQRWAPHAPDHLNAEVAIQSADPSADPKVTLFGATLGRADAARAALAEFLASA
                     APGHELDELTELSPAAAPLRHSYAGAAVLEHPQPGPPAGLRPLLRAVKSEFFDTALPEP
                     AITALLANFAADRRPAQYRELEFIPWGGMIGKPDPGATAFTHRNQLFQIGHHGMVPNPA
                     GDDARAAARGWAKRSWRSVHPWAAGGVYPNYPDADLPDWARAYYGDNLPRLTEVKARYD
                     PDDVFHFAQSIPATAGAPRHRADGGPDRGGSNGPATPP"
     gene            complement(8079..10004)
                     /locus_tag="JQS43_RS10365"
                     /old_locus_tag="JQS43_10315"
     CDS             complement(8079..10004)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012546.4"
                     /locus_tag="JQS43_RS10365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10315"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_239678854.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 6.9e-20, bitscore:
                     69.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGATRHRVTIGFASDGRRAARLAADSADAGRVASWTLTPHGPHR
                     GFSATVTGAATGAQALPLPGDRLLYAKLTPTGRQLQLLARRGVLAAAPAPALRTLVADP
                     TGAAIGVGPTAGGGTALYRIADDLTGASADDGPVARFPATLHGPALVVGARLLFHARIG
                     GRTTPVWFDPQTATLTPWLLPGPAGHTVPVCATGDQVVLALSTEARSRLVVAAPGRPGL
                     LQPIEDLAVPAGRVRPLALRPDGAELALRVRIGVRYRLLLHHRHAGETREVDLPPGTPD
                     QVAAWTDHGLWLGFSPTTAPAGLWWLPPGGRTLLPPPGTPVARPAQVESLPGPAGPIET
                     ITYGDWRAADRVVLALHGGPAEHWQLRFEPKLRAVAARAAVVAPNQRGSTGYGRDHELA
                     IRGAWGGPDLADILALGAHLSAVRGDCAARPSLYGVSYGAFLALLAMAAEPEYWSGVVA
                     VAPFLSGAALRADANPPVRALIDRLDGVAPVVDEYGARDLLRVAAGMRGRVLLLHGARD
                     QTVPVGHSRRLAAALSAAPGVDLTYREVAEAGHDPVPTDPASPTLAELVRFLSPDPLDP
                     PDPPHPAAPATTDRLPGRAAVTDDDAGRLAGWRTTPEGGEQYGSRAGVRAGGAGAAASR
                     GGADRG"
     gene            complement(10001..12724)
                     /gene="lanL"
                     /locus_tag="JQS43_RS10370"
                     /old_locus_tag="JQS43_10320"
     CDS             complement(10001..12724)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="JQS43_RS10370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10320"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_239678855.1"
                     /sec_met_domain="Pkinase (E-value: 1.7e-17, bitscore: 61.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.2e-41, bitscore:
                     138.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRASLDPLPLRELLALLLAGASGDGWQVREDDHWCHVTPRSHPAR
                     VQGWKLHISATWLSAPTVLHRAAQVLLGRSCAFKFAGSMRRVIELTSKNAERSQAGKFI
                     TVYPRDDEELRALAPILDQATAGLPGPAVLSDRPVRPGSLVHYRYGTFHGVPVLTNDGW
                     FESRLEAPDGALVADARRPWFSPPPWTTLPFEGSPGRSADRPAKPRPVLLDGRFRVAKA
                     LTQTARGGVYRAVDQQTGARVVVKQARAHISGLSHVGDARDALRHEAEMLSRLAGVAPA
                     VVALFEQGDRLFLAVEELTGQPLRGWVRARWQAAPDTGLPTDEAVAIGRQLANLVETVH
                     QQGLVFRDLTPGNVMVADGGELRLIDAELATPPGTWVAQAHTPGFAAPEVLAGPAVGPA
                     PGPAADHFALGVLLCHIVTGGPAALPPDTPTSVTDGDTAAGRSITDRLTLLLRYAAVDN
                     PAAARLAPAILGLTAADPAQRWDLDRLRGHLSEPAPAAPAPADGAAAAGRLCPDRQAQL
                     LTDGVAHLVTALAAAPGERLIRNSPQVARADPGNVQYGAAGVLGVLVRANELLDAADLA
                     TTVTRVARWLDARRTAVPKLLPGLYFGRSGTAWALHTAARHLTDEAMAERALELAAAIP
                     VEWPNCDITHGTAGAGMASLQLWTQTKEPAFRARVDTAVDHLLERVEVSTDGDVCWRVP
                     ADFDSRLAGAASYGFAHGVAGIATFLLAAARATGRADARTLAVQAGQTLVRAAVRRAGA
                     AYWPNELTGPTDADLRYHWCHGASGVGTFLVRLWRETGEETYRELAHEAAVMVRRGRWL
                     VGTSYCHGLAGDGEFLLDLAAASDPGAPYHGWAAESAACLYARHARRDGRMVVSDELTT
                     RLPLDFGTGLAGVVGFLLRLRHGGPRWWLCDVPEQP"
     misc_feature    complement(10934..10936)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11453..11455)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12888..13607
                     /locus_tag="JQS43_RS10375"
                     /old_locus_tag="JQS43_10325"
     CDS             12888..13607
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015866.4"
                     /locus_tag="JQS43_RS10375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10325"
                     /product="copper homeostasis protein CutC"
                     /protein_id="WP_239678856.1"
                     /transl_table=11
                     /translation="MRLEIATQDVEGVRVAQARGADRVELCQALPVGGLTPSQGLVEQA
                     VALGVPVRALIRPRAGGYRYTATETATMVRDVATAVAAGAEGVVVGALTDDGLDRAVLR
                     ALVHAAAGAPVIVHRCVDVLLGQGWVAPAALVAQLLELGVAGMLTSGGAERAPDGRDTI
                     AALAAAAAGRLEIVAGGGVRPEHFAALARAGADTVHLSAGRAVSAGPSGPGGGEDEFVT
                     TDPAVVAAARAAVDALT"
     misc_feature    complement(12900..12914)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            complement(13649..13978)
                     /locus_tag="JQS43_RS10380"
                     /old_locus_tag="JQS43_10330"
     CDS             complement(13649..13978)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020510667.1"
                     /locus_tag="JQS43_RS10380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10330"
                     /product="L-rhamnose mutarotase"
                     /protein_id="WP_239678857.1"
                     /transl_table=11
                     /translation="MRVALHTRVKAGREDDYDAAHREVPADLVRAIRAAGATSWTIWRS
                     GQDLFHVIECDDYGALLASLVELPVNIAWQDRMAELLAVSHDYSTDGAGAGLPVVWELG
                     AESVD"
     gene            complement(13981..15318)
                     /locus_tag="JQS43_RS10385"
                     /old_locus_tag="JQS43_10335"
     CDS             complement(13981..15318)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020525359.1"
                     /locus_tag="JQS43_RS10385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10335"
                     /product="enolase C-terminal domain-like protein"
                     /protein_id="WP_239678858.1"
                     /transl_table=11
                     /translation="MATIKALDTHDLRFPTSRQLDGSDAMNPDPDYSAAYVVLRTDEST
                     SDGEPLGGYGLVFTIGRGNDVQTAAVDALRDHVVGTDLDELCADLGGFARRLTGDSQLR
                     WLGPEKGVMHMAIGGVVNAAWDLAARRAGKPLWRFISDLTPDEIVACIDWRYLTDALTP
                     DEARAILTANLASRDARRAELAERGYPAYTTSPGWLGYSDDKLAALCRSAVADGYRTIK
                     LKVGRAVDEDLRRLRVARATVGPEVRLAVDANQRWDVAEAVDWLTALAGFDLAWAEEPT
                     SPDDILGHAAIRRGVQVPISTGEHTQNRIVFKQLLQAEAVDLIQIDATRVGGVDENLAI
                     LLLAHKFGVPVYPHAGGVGLCELVQHLAMADFVAISGSMQDRAIEYVDHLHEHFTDPVR
                     IVAGRYQAPTAPGMGGRLTERSVAEHSYPDGPVWRVATTEQPEGGR"
     gene            complement(15327..16850)
                     /locus_tag="JQS43_RS10390"
                     /old_locus_tag="JQS43_10340"
     CDS             complement(15327..16850)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018811484.1"
                     /locus_tag="JQS43_RS10390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10340"
                     /product="M81 family metallopeptidase"
                     /protein_id="WP_239678859.1"
                     /transl_table=11
                     /translation="MSSRATPLPRVAIVGIAIESSTFSPHRAGLADFVVRRGTELLDYY
                     PFLTPGQPLRERAEWVPLMQARSIPGGAVRAETYQQLERATLDLLAAHGPFDGVFFDIH
                     GAMSVEAQTDAEGGLATRVREVVGPTAMVSASMDLHGNVTRQLLDAVDLITCYRMAPHE
                     DAMESRERSVRNLLDRLDSGRRPHQAWVPVPVLLPGEKTSTRVEPASRIYAEVPKVEAL
                     DGVLDAAIWVGYAWADEPRCRAAVVVTGDDPELASQQAERLARAYWQARAEFSFVAPAG
                     TLDECLAEALASPARPFVLSDSGDNPTAGGAADVTWTLARLLAHPAFATGELTGVYAAI
                     PDAAGARAAAAAGVAADVSITVGARVDDRHQGPVTLTGTVAHVSTTDPVAGTVAVVAVG
                     GLRVIVTERRKPYHTAEDFSHTGIDPAQADIVVVKIGYLEPYLYELAADWRLLLTPGGV
                     DQDLLRLGHNDIQRPMFPFDPDMPDPDLTAVVVPPRDRRTPGLVPSQER"
     gene            complement(16847..17980)
                     /locus_tag="JQS43_RS10395"
                     /old_locus_tag="JQS43_10345"
     CDS             complement(16847..17980)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012692.4"
                     /locus_tag="JQS43_RS10395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10345"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_239678860.1"
                     /transl_table=11
                     /translation="MVTHRIVELVSTGAATSRADLARTLAISPSTVSLRVQELVDAGVL
                     YEHSHGVSRGGRPPRTLRLHDHGGYVGVAEIGSHHARVGIIGLTGRLDRSANLTVDATA
                     GPEPTLRSLASTMSELGVDVPGDLRAVAVALAAPVDAQARTVVQASRLATWNGYPVGDW
                     LEKQLDVPTVVENDVNAMALGEHYERAEHGFDSVTVKAGSAIGSGLIVDGRIYRGSTSN
                     AGDITHTRVASAGDTPCSCGNLGCLETVASAAGIIRLLRERGVAVSGTPELVTVAGQGH
                     AQAMSLVRSAGRHLGEVLSTVVNFVNPGAVYLGGALSTLEPFVAAVRSQLYEGCHPLAT
                     RDLVIEPTRTGADAGVIGAGRLALTAAFADSAAERTP"
     misc_feature    complement(17642..17644)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17947..17961)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            18209..19486
                     /locus_tag="JQS43_RS10400"
                     /old_locus_tag="JQS43_10350"
     CDS             18209..19486
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013300.4"
                     /locus_tag="JQS43_RS10400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10350"
                     /product="alpha-L-fucosidase"
                     /protein_id="WP_275581088.1"
                     /transl_table=11
                     /translation="MTVSQQAGWFTHDRFGLFVHFGLYSPLARHEWVMTREQTPPEEYE
                     QHAPFFDPDRFDPRAIARAAKDAGMRYVVLTAKHHEGFALWDTALSEYNATKVTGRDLV
                     REFVDAVRAEGLRVGLYFSLIDWHHPDFTIDYHHPLRNLPDARERNQHRDMARYREFLH
                     GQVGELLTGYGKLDYLFYDFTYSEPRDGWEGKGPQDWDAERLLAMTRELQPGIVVNDRL
                     GIPADLVTPEQYQPDAPMRRDGRDVVWEACQTLNGSWGYDRDNLDFKSPDLLVRMLVDT
                     VAKDGNMLLNVGPDGRGALTPRDQESLAAIGRWMELHGRSVVGAGAAGLPAPPGTVLTR
                     RGDRLYLHLLVWPFGHLHLPELAHRVRFARFLHDGSEVRRSQIDPGQQAWNTVPGGQPP
                     GTLTLHLPTARPAVEVPVIELVLTDE"
     gene            19551..20795
                     /locus_tag="JQS43_RS10405"
                     /old_locus_tag="JQS43_10355"
     CDS             19551..20795
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /locus_tag="JQS43_RS10405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10355"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_239678862.1"
                     /transl_table=11
                     /translation="MRNRTRTAVAAAAGAALLLAAGCGDSGGDGDGTVVFDMWAGGDDE
                     VDALRAQVEIAEEETGVEIRLRTSPWNDFFTQLTTRASSGEMACLTGMNGQRLGDYADA
                     FLPLGEEELATAGIDPADFTEGSLDIMSHEGNLYGIPYDVATMIVYYNKDMLDEAGVPE
                     PAAGWTFDDFEDTIAGATTDAQPGFGVGMAEFQWMSLPIARSGVQPVTEDRQLDLTNPA
                     FVEASEWYFGLVDEGYAAVPGSASDTGWGEEQYQNANTAVALDGTWNAVTYLNNDAGFR
                     AGMVELPSQGGERLGLVLGSGYGISADCDDPETALQVLGALVGEAAQDEVASSGRSYPA
                     RSSSQPLYFEALDDEIRDEVEAAFEAAFTDLEGQYSTDNWTQINEAIQPNLISVYAGQM
                     TPAELLEQTQQQFGG"
     misc_feature    19746..19748
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20792..21739
                     /locus_tag="JQS43_RS10410"
                     /old_locus_tag="JQS43_10360"
     CDS             20792..21739
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.4"
                     /locus_tag="JQS43_RS10410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10360"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_239678863.1"
                     /transl_table=11
                     /translation="MTERECEAVTTLTGSTKRRRGGNQLRRIETRQALGFISPALAGLA
                     LFTAFPVVLSIAMSFYQWPAIGEREFVGLDNYVNLFQNHPDFIPALRNTIVFTLLFVPL
                     NLVVSLTLALALAPRIRGRAAFRVLFFLPVVTPIVANVLMWKILLQPNGLLSGASSSLF
                     GVTLPNFLAHPTWAMVMVVVMSVWAGMGYNMLIFSAALEQLPESVLEAARIDGAHGYRM
                     LLRVIVPLISPAIFFATVMTMITAMQVFAQPQLLTGGGPGNSTMPLVMFIYNQAFTFQQ
                     MGLAAAAAWILFAFIITLTAVQFRAQKRWVHYEV"
     gene            21729..22637
                     /locus_tag="JQS43_RS10415"
                     /old_locus_tag="JQS43_10365"
     CDS             21729..22637
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.4"
                     /locus_tag="JQS43_RS10415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS43_10365"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_239678864.1"
                     /transl_table=11
                     /translation="MRSDVVEAKGVGVAPVRGGHGVPRRDTGRSTARSVLAHTFVVIAA
                     LIFATPLIWAFFSALKPNHEMFASPPSLFASEVRWSNFLEVFQYGPFVTYIRNSFLISV
                     AGTVLVLVVSACAGYAFGRLRWRGRDLVFIIFLATLMVPQEVLVVPMYQLMLWFGWVNT
                     PQSLVLPFAFTAFGTFLMRQFLRGIPFELEESARVDGAGPLRTFLFIILPLARPALAVL
                     TVFTFISFWNSYLWPLIVISDYGSLGTLPIGLATFAGQFGTRWDLQMAATIISMIPTTL
                     IVILLQKHLVKGISTAGLGGR"
ORIGIN
        1 ccgacctcca gcaactgctg gatcgctacc gcacccacta caaccaccag cgtcgccaca
       61 gcgcccttcc cggccgggcc accccccagc aggcctggac cagcgcagcc agcctgggcg
      121 ggcccgacag cccacccatc cagaccgacg ccaccctgca ccgctgcacc gtcgccgcca
      181 acggcaacat ccgaatcggc cgccacacca ccagcgtcgg catcgcccgc gccggaggca
      241 ccgtcaccgc cgtccgcaac ggcgaccacg ccaccgtcta cagcaccgac ggtcaaccca
      301 tcggctatgt ccacatcgac cctgccaaga gatacgccgc actcaccaga accgaatgat
      361 cagctaacca tgacacatgt cccgggacat taacttgaca catgtcccgg gacatgacag
      421 tcgcagctac gacaacaatc gcacaacctt gcgggagtac gacggcgatg cgccgccact
      481 gcgcggcaag atgtccgcgg cggctacgag acaccgaacg ggccgcggca cccaacgccc
      541 gcccgtaacg accctcgacc cggcggtcgc cacctcattt tcacgctaca gggcgctcga
      601 cacgagcccc ccgattggtt ggctggggag ggatcttgcg tacggataag tccgacattc
      661 ctgtacgcaa gatccctccc cagccaacca acatgggcgg gggttgctgc gacgggcgga
      721 gagctgcagc cgcccgcacc tcggcagccg cggcggccgc agctgagggg actaccggtt
      781 cgttgcaccg ggcgatcttg tgtagttctc cccgctgggt cggctcatcg gcaacgcggt
      841 cccacccctg ctcgccgcgg ccgtgggccg agccatcgtc gatcacgtga ctgcccgata
      901 gctcaggtcc ggccggccgc tcacgggtat ggcggcaaga ccggtctcag agctcaaggg
      961 gctcgaccgg ggtgatggtg ggggtgaaag cgatcgcgtc gaagctgtcg gccagcgacg
     1021 ggaactcgta gtagtggtcg tcgtcccggg ctgggtcgta gcggccggag attagccgga
     1081 tctgccaccg acggtcgagc gccacgggcg ggtcagccgc agcggcagcg cgcaggtcga
     1141 cgactcgctc tccgccgccg gcggtgaggg tcccctccag cgaaccagcc cgagccggcg
     1201 gaatctcgtg ccgcggcgtc cgtcccgcac cgaaggtgag gtggaccgcc acatactggt
     1261 caccgagcgc ctgccgaagg tacgagccga gggtcgggcc gccgtgggcc gcgacgtggg
     1321 cgctgccctc ccatagcacg atccggtcac cgctggcctg atggtgcgca aggagcctgg
     1381 tcgccgcggc ctgctcggcc cggtcctggt cgtagccgac cccgatagcg tcggcgtgga
     1441 attcgacgat caggtcgagc agccgcaccg cctcgtcccg ttcggcgccg tcgggcagcg
     1501 ccgctgtagc ctcccggccg gcccgggcga gctcgacgaa cggcgtaccc ggatgggtgc
     1561 cgagggcgcg cagcacgtgc tcaccggtgc tgtgcgccct ccggatcacc tcgagtgggc
     1621 cgcgggccgc cgctgccgcc ggtggatcga tgccgtcgag caactccagc acccggtcgt
     1681 agtcggccgg caacgctcgc gggccctcga tcccgaggag ccgcaccggg tcgttcgggt
     1741 ggcgccggtt gtgttcccgc agtgcggtca gtgtctgtcg catctcgacg acctgccacg
     1801 gcccccaggc ttgggcgagc acactgtcga ggtcgagatc ggcgccgccg aggtactggt
     1861 cgtagagttc gccgacgcgt tggttgtcga ggatcgcgat cgtgcggaag cctcgctcga
     1921 cgaggcgcaa ggtggtcgct tcgacctgcc ggaacagctc gtgcgcctcc cgggtgctgg
     1981 tgccgagccc gaccacggtg gcgtgctcgg cgaggttggt gatcaagtca gcggtgcggg
     2041 tcggttgcgt ggtcatgccg cccagcatcg ggcttaaacc aatgttgaag tcaagcgccg
     2101 cttcggaaca aactcgtagg ccggcgctac taccggcggg tgcgtacggc ctgaaactcg
     2161 ccgtacctgt cgccgaagct gtacggcggg cgaagcgacc ccgtggcgtt cgcgatatcg
     2221 cggacggtta acgccgcaac tggcgcagtg gtggaggtca cctttcccgc gtagtcagcc
     2281 gagttgactt caacataagt tgaaccagga acctgctcgg tatgactact tcgacctcac
     2341 atctcgccgg cccggcaacc gtcgccaccc cgcagatcgc ggttatctcc gccagcgtgc
     2401 gcgcggaccg gatgtgcccc tcgatcgccg actgggtcgt cggcgcgctg actcccgacg
     2461 ccaccgtgga cctcatcgac ctggccgagg tcaccttgcc cgatgactcg ctgctctacc
     2521 cgggcggcgg acccaagagt gaagtggcgg ggcggatcga ggcggctgag gcgttcgtct
     2581 tcgtcacccc ggagtacaac cacagctatc cggcttcgct caagcgcctg atcgactggc
     2641 actacagcga atgggagctg aagccggcta ccatcgtggg ctacggtgtc tatggtggtc
     2701 actcggcgat cgagcacctc cggggggtgc tggccgagct cagcgtggtg acgacccgcc
     2761 gggtgctggg gctgagtcag ccctgggagc acctgtccga ggacggcggc tacaccccgg
     2821 acgagggtgc cgcgcgcggc ctggcagcca ctgtggccga gctgatctgg tgggcggagg
     2881 tgctcaccga cgcccgcacc aaccgccccc gccccggcca atcatgagcc ttcccccacc
     2941 cggccgatca tgagcttgtt gaccgacacg ccccgcttcg gttcaaccgg tccgtgcaag
     3001 tggttcgttg accacggcat ggaccggttg aacggagtgg gtgcatggct cgggcgcatg
     3061 tgttgacgtt ggggcaccgg caggtgatcg agaacctatg gcggcaggga tcgaccttcg
     3121 agcggatcgc ggcagcgctc ggggtgggat tctcgtcggt atggcgggaa atcgcacggt
     3181 cgcattcctc gcggcatgga acgaaaaacc cgctcgggcc ggtgcggggc gggctgtacc
     3241 ggtggggcta caccgcccag tgggcgcagc gacacgccga gaagcggcgt gcgcggccta
     3301 aaccccgccg actggaccac aaaccgttgc gtgagcaagt cgctacctgg ctgcggcaac
     3361 gttggtcgcc tcagcagatc acccactcct tgcggcgtac cttcacaggt atgccccaga
     3421 tgcaggtcag ccacgagacg atctacaagt ccatctatct gcaggcgcgg ggaagtctgc
     3481 gggagctggt caacgacgcg ctacgtaccg gccgtaagca gcggcgttcg cagtcccgcg
     3541 ccgcgcaggc cgcccggggg gcgatccgtg gtaagccgtg ggtgaccgag caggtgcata
     3601 tctcggcgcg tccggccgag gccaacgacc gggcagtgcc cgggcattgg gaaggtgacc
     3661 tggtcctggg ccgtaacaac gcctcggcga tggtgactct agtggagcgc accacccggt
     3721 ttgtgatgct cggcgcattg cctgttgacc gctccagccc ggaggtattg acggtagtgc
     3781 gcggattgat ggcccgcctg ccgcagcatc tagtgcgttc gctgacctgg gaccagggaa
     3841 gcgaactggc tggtcatgcc tccttcaccc tggccacagg ctgcccggtg ttcctgtgtg
     3901 atccgcactc gccctggcag cggggcacca acgaaaacac caacaggctg ctgcgtcagt
     3961 actacccgag aggcaaaacc aacttctctg tcgtcagcca ggccgagatg gacacggtcg
     4021 cggtgtcgct gaacggccgt ccgcgggaga ccctgggatg ggatactccc gcggaggcct
     4081 tgaatcaact actccttgca ccgaccgctt gaaaccaccc cggcgtgtcg gtcaacaagc
     4141 tcatgatcgg cgcgaggtga tcggccaagc ggggatcggg gcgaggtgtg gcggaggtgg
     4201 cgggcggcga gggtggctat cgtgagcgag tggcagacga acctcgggcc ggcggcctca
     4261 cgatcgtcga cgtggcggtc ttcgacgggg tgtccggcga gctgaccgac ggtccggtgc
     4321 acatctcgga cggtgtgatc accgcggtcg gcggtcgtcc gcaccccgcc gaccaggtga
     4381 tcgacgcgcg gggcggcacc gtcatcccgg gcctgatcga cgcgcacttc cacgcgtacg
     4441 gggtcggcct ggacctcttc cggttggagg cgacgccccg cagctatgtc gcgttggccg
     4501 gcgcgcgccg gctgagcgcg gccctgtcgc gtggtttcac cacggtgcgg gacgtcgctg
     4561 gtggtgaccc agggcttgct agggcgatcg acgaagggtt ggtcgcgtcg ccgcgctacc
     4621 tctacaccgg gcctggcctg tcgcagaccg gcggtcacgg cgacgggcgc cccggtgacc
     4681 tggagctgtg cgcctgcggt ggccagctgg ccgaggtggt ggacggcgtg gacaacctgc
     4741 gacgggcggt gcgcgaccgg ttccggcgcg gcgcccacgc catcaagatt atggcctcgg
     4801 gtggggtggt ctcgcccacc gatccactac ggatcccgca gtactctccg gaggagatcc
     4861 gggccgtcgc cgacgaagcc ggccgtcggg gcagctacgt ggcggcccac gcgtactcac
     4921 ccgaggcgat cgtggcggcg gtccgcaacg gggtccgcac catcgagcac ggcaacctgc
     4981 tagacgctga cgccgcccgg agtatggccg agcacggcgc ctacctggtg cccaccctgg
     5041 tgacctacga cgccatggat cggcggggcc gcgaattcgg gctggcgccg gtgtcgcagc
     5101 agaagaaccg cgaggtgctc gacgccggcc ggcaggccat cacgctggcg cgggcggcgg
     5161 gggtgccggt cgggttcggc accgacctga tggggccgct ggaggatgag cagcttgctg
     5221 gtttgcgact gcaggtcgag gtggacggag tggtggcggt gctgcaatcg gcgacggcgg
     5281 tcaacgccga ggtcctgggc cgccctgacc tgggccgggt ccaggtcggg gcggtggcgg
     5341 acctggtcat tcttgatggt gacccgctgg ccgatccgtc ggtgctgtgg gccggcgccg
     5401 accggcggac ggtaatccag gccgggcggg tggtgtcacc tggccggctc ggcgccgcca
     5461 gcgaacgggg gagcacgcca tgagcgatcc aatcggtacg ccgcccggcc cgcctgagcg
     5521 gccagttgag gtggcccgcg ccttcctgga tgcgttggcc gcgcgcgatg ccgccaccgc
     5581 cgcgagcttc ctcgcaccgg acgtgacctt cgaaggtcca cagtcgagac tgcagggtcg
     5641 ggaagccgtc ctcgaggaac tgcggcagtt cgctgagacg gttactgcgg tgacagtcat
     5701 cgcagcgctc ggcgatgagg cggaggccat gctgctctac gacgtcgatg ctggtgagat
     5761 cggcaggcta cgggtggctg accacttcgc cgtgcacgac gggcggataa ccgccaacac
     5821 ggcggtcttc gccgcgctcg actagcggtc gccagcgcca gcaacggtcg gtcttcgcgc
     5881 ggtctgccga gtttcgcaag tatcctgcca agtctcgttc gggtggtagg cgccggagcc
     5941 ggctaatcac taccgtctag ctgtgacgat cattcccgac cgtaagaact ggacctgggt
     6001 gctggagcgg gcctgtcccg agtgcggctt cgccgcccag tcgattcctc gcgagcagat
     6061 cccggcccgg ctccgggcct gcgccgacca gtggcggctg gtgctgagcg gcgtggtcat
     6121 gacgggtggc gcggcgaccg cggaagcggt gcggcagcgg ccccgccctg atgtctggtc
     6181 gccgctggag tacggctgtc acgtccggga cgtctgccgg cgcttcagcg atcggctggc
     6241 gcagctgctc gccgaggaag cgccggtctt cgccgactgg gaccaggacg cggccgcggt
     6301 cgccggccgc tacgccgagc aggagccggc gcgagtcgcc gccgagttgg tggccgcagc
     6361 ggcccggctc gccgacgggt tcgaggcggt gaccggcgag cagtggcggc ggaccgggag
     6421 ccgcagcgac ggcgcccagt tcacggtgga gtcgctgggc cgttacttcc tccacgatcc
     6481 ggtccaccat ctgcacgatg tcggggtgct ccggcggtag ccggaatcga ctgggcgaag
     6541 tggaacacat cgtccgggtc gtaacgtgcc ttcacttcgg tcaggcgggg caggttgtcc
     6601 ccgtagtatg cccgtgccca gtcgggcagg tcggcgtcgg ggtagttcgg gtagacaccg
     6661 ccggcggccc acgggtggac cgatcgccag gaacgctttg cccagccgcg ggcggcggcg
     6721 cgggcgtcgt cgccggctgg gttcggcacc atgccgtggt gtccgatctg gaacagctga
     6781 ttccggtggg tgaacgcggt cgcccccggg tcgggcttgc cgatcatgcc gccccacggg
     6841 atgaactcta gctcccgata ctgtgccggc cgccggtcgg cggcgaagtt cgccagcagg
     6901 gcggtgatcg ctggctcggg tagcgctgtg tcgaagaact ccgacttcac cgcccgcagc
     6961 agcgggcgca gcccggccgg cgggcccggc tgcggatgtt ccagcaccgc ggcaccggcg
     7021 taggagtgcc ggagcggggc ggcggctggt gacagttcgg tgagttcgtc tagctcgtga
     7081 ccaggggcgg ccgaggcgag gaactccgcc agtgcggcgc gggcggcatc ggcgcgaccg
     7141 agcgtcgccc cgaagagggt caccttcggg tcggcgctcg ggtccgcgct ctggatcgcc
     7201 acctcggcgt tgaggtggtc cggcgcgtgt ggtgcccacc gctgccaggc gtcgatcagc
     7261 gccgcggcat ccgcccacgg ccaacggtgg acgaagcggc acatccgctg caccggaaag
     7321 gttcgcagca cgagcgccgt caccaccccg aagccggccc agccggcgcc tcgcagagcc
     7381 cagaagaggt ccggttcccg ttgttcgtca acccaaacga tgtcgccgtc ggccagcacc
     7441 acctgcgccg cgagcagctg gtcgcagccc aacccaaagc ggcggctcag caccccgaac
     7501 ccgccgccca gcaccgcacc gccgaccgct accagtggat tccagccgca tgacacgatc
     7561 cggccctgca cagccagccg ctgggcgagc gggcccaacc gtacgccggg gccgatcgtg
     7621 gctgtctcgc cggccagcgc gaccgtgtcc aaccgcccga ggtcgatcag cagcccgtcg
     7681 gtggcgcagt ggtcggcgaa gctgtggcca ccgctgcgga tggcgaccgg cagccggtgt
     7741 ttccgggcga aggtcaccgc ccgcgctacg tccggcgccc cggcgcaccg gacgaccgcc
     7801 tgcggcagca cctcggtcag accgccgacg aacggccgac ggagcgagct gaactcggtg
     7861 tcgtcggggc ggaccagcga gccatcgagc gtggtcgcaa gctcgcgcca cccgggggct
     7921 gtcgtcgcca cccactgtcc tttcaggatt ttagcgccgg cgccgtggtc ggcgcggcgg
     7981 ctggcggggg ccgaaccggc tcgtgcgcga ggctcggccc ccaccagacg tgctagggca
     8041 gaatgtagag catgctgtcg aagtagcagc cgctcaggtc acccccggtc agcccctcct
     8101 cggctggcag cagctccagc gcctccggct cgaactccag ctcgagatcc atattgttca
     8161 cctccttccg gagtcgtccg ccaccctgcc agccgacccg catcatcgtc ggtgacggca
     8221 gctcggccag gcagtcggtc ggttgtcgcc ggagccgccg ggtgaggcgg gtccggcggg
     8281 tccaacgggt ccgggcttag gaaccgcacg agctcagcga gcgtcggcga cgccggatcg
     8341 gtcgggaccg ggtcgtgacc ggcctcggcc acttcccggt aggtcaggtc gacacccggg
     8401 gcggccgaca acgcggccgc cagccgacga gagtggccca ccggaaccgt ctggtcacga
     8461 gcaccatgca gcagcagcac ccggccgcgc atccccgctg ccacccgtag cagatcccgc
     8521 gctccgtact cgtcgacgac cggcgccacc ccgtcgagcc ggtcgatcag cgcccggacc
     8581 ggcgggttag cgtcggcccg cagcgcggca ccgctcagga acggggccac tgcgaccaca
     8641 ccggaccagt actccggctc ggccgccatc gcgaggagcg ccaggaacgc cccgtagctg
     8701 accccgtaga ggctgggccg ggcggcgcag tcgccccgta ccgccgaaag gtgagcgccg
     8761 agggcgagga tgtcggccag atccgggccg ccccaggcgc cgcggatggc gagctcatgg
     8821 tcgcggccgt agccggtgct gccgcgctgg ttcggcgcca ccactgcggc ccgggcggcc
     8881 accgcccgta gcttcggttc gaaccggagc tgccagtgtt cggccgggcc cccgtgcagt
     8941 gcgagcacca cccggtccgc ggcccgccag tctccgtagg tgatcgtctc gatcggcccg
     9001 gccgggcccg gcagcgactc cacctgagct ggtcgcgcca ccggcgtgcc cggcggcggg
     9061 agcagcgtcc ggccgcctgg tggcagccac caaagtccgg ccggtgcggt ggtcgggctg
     9121 aaccccagcc acagcccgtg gtcggtccag gcggccacct ggtccggtgt cccgggcggg
     9181 aggtccacct cccgggtctc gccagcgtgc cggtgatgca ggagcagccg gtaacggacg
     9241 ccgatgcgga cccgcagcgc cagctcggca ccgtcggggc gcagtgcgag cggtcgcacc
     9301 cggcccgccg gcaccgccag atcctcgatc ggctgcagca ggcccggccg gcccggcgcg
     9361 gccaccacca gccggctccg ggcttcggtc gagagcgcga gcaccacctg gtcaccggtg
     9421 gcgcagaccg gcaccgtgtg gccagccggc ccgggcagca gccacggggt cagcgtcgcg
     9481 gtctgcgggt cgaaccagac cggggtggtc cgcccgccga tccgggcgtg gaacagcagc
     9541 cgcgcgccga cgaccagggc cgggccgtgc agcgtggcag gaaaccgcgc caccggcccg
     9601 tcgtcggcgc tggcgccggt gagatcgtcg gcgatccggt agagcgcggt gccgccgcca
     9661 gcggtcggac cgacgccgat cgctgcgccg gtggggtcgg cgacgagggt gcgcaacgcg
     9721 ggtgcgggcg cggcggcgag gaccccgcgc cgagcgagca gctgtagctg ccggccggtc
     9781 ggggttagtt tcgcgtagag cagccggtcg ccgggcagcg gtagcgcctg ggcgccggtc
     9841 gccgcgccgg tcacggtcgc cgagaacccg cggtggggcc cgtggggagt cagcgtccac
     9901 gaagctaccc ggccagcatc tgccgagtcg gcagcgagcc gagcggcgcg ccggccgtcg
     9961 ctggcgaacc cgatcgtgac ccggtgtcga gtggcgccgc tcatggctgc tccgggacgt
    10021 cgcacagcca ccaccgcggt ccgccgtgcc gcagccggag caggaatccg accacgccgg
    10081 cgagcccggt gccgaagtcg aggggtagcc gggttgtcag ttcatccgag accaccatcc
    10141 ggccgtcgcg gcgggcgtgg cgggcgtaga ggcaggccgc ggactccgct gcccagccgt
    10201 ggtagggagc cccagggtcg ctggcggcgg ccaggtcgag caggaattcg ccgtcgccgg
    10261 ccagcccgtg acagtaggag gtgccgacca gccagcggcc ccgccgcacc atcaccgcgg
    10321 cttcgtgcgc caactcccga taggtctctt cgccggtctc gcgccacagc cggaccagga
    10381 aggtgccgac cccggaggcg ccgtggcacc agtggtagcg caggtcagcg tcggtggggc
    10441 cggtcagctc gttcggccag tatgccgcgc cggcccgccg taccgccgcg cgtaccagcg
    10501 tctgtcctgc ttggactgca agggtacgcg cgtcggcgcg gccggtggcg cgagcggctg
    10561 cgagtaggaa ggtggcgatc ccggcgacgc catgggcgaa tccgtagctg gcggcgccgg
    10621 ctaggcggga gtcgaagtcg gccggcaccc gccagcagac gtcaccatcg gtgctgactt
    10681 cgacccgttc gagcaggtgg tcgacggcgg tgtcgacccg cgcccggaac gccggctcct
    10741 tggtctgggt ccacaactgc aggctggcca tgccggcgcc agcggtgcca tgggtgatgt
    10801 cgcagtttgg ccactcgacc gggatcgccg cggcgagctc cagggcgcgc tccgccatcg
    10861 cctcgtcggt caggtgccgg gccgccgtgt gcagcgccca ggcggtgccg gaacgcccaa
    10921 agtagagacc tggtaagagc ttgggtacgg cggtccgccg ggcgtcgagc caccgggcaa
    10981 cccgggtcac ggtggtcgcc aggtcggccg cgtcgagcag ttcgttcgcg cgtaccagta
    11041 cgcccagcac cccagcggcg ccgtactgca cattgccggg gtcggcgcgg gcaacctgcg
    11101 gcgagttgcg gattagccgt tcgccggggg cggcggcgag cgccgtgacc aggtgggcga
    11161 cgccgtcggt gagcagctgc gcctgccggt cggggcagag ccggccagcg gcggcggcac
    11221 cgtcggccgg tgcgggcgcg gccggcgctg gctccgacag gtggccgcgg agccggtcga
    11281 ggtcccaccg ctgcgccggg tcggccgcgg tcaggccgag gatcgccggc gcgagccggg
    11341 ccgctgccgg attgtccact gcggcgtagc ggagcaagag tgtgagccga tccgtgatcg
    11401 accggccggc cgcggtatcg ccatcggtga cgctggtcgg ggtgtccggc ggtaacgcgg
    11461 ccggaccgcc ggtgacgatg tggcacaaca acacgcccaa cgcgaagtgg tccgccgccg
    11521 gccccggagc cgggccgacc gccggcccgg ccagcacctc cggggccgcg aagcccggag
    11581 tgtgcgcctg cgccacccac gtaccgggcg gggtcgccaa ctcggcgtcg atcagccgca
    11641 gctcgccgcc gtcggcgacc atcacgttgc cgggggtcag gtcccggaag accaggccct
    11701 gctggtgcac cgtctcgacc aggttggcca gttgccggcc gatcgccacc gcctcgtcgg
    11761 tgggtagccc ggtgtccggc gctgcctgcc aacgggctcg aacccacccg cgtagcggct
    11821 gacccgtcag ctcctcgacg gcgaggaaca gccggtcgcc ctgttcgaag agcgccacca
    11881 ccgctggggc caccccggcg agccggctga gcatctccgc ctcgtggcgc aacgcgtccc
    11941 gcgcgtcgcc gacgtggctg agcccagaga tgtgggcccg tgcctgcttc acgaccaccc
    12001 gcgcgccggt ctgctgatcc accgcgcggt agacaccgcc gcgcgcggtc tgagtgagcg
    12061 ccttcgccac ccggaaccgg ccatctagta gcaccggcct tggtttggcg ggccgatcgg
    12121 cggaccggcc cgggctcccc tcgaacggga gtgtggtcca cggcggcggg ctgaaccacg
    12181 gtcgtctggc atccgccacc agggcaccgt ccggggcctc caatcgcgac tcgaaccagc
    12241 cgtcgttggt gagcaccggt acgccgtgaa aggtgccgta ccggtagtgc accaggctgc
    12301 ccggccgcac cgggcggtcg gagagcaccg ccggcccggg cagccccgcg gtcgcctggt
    12361 ccaggatcgg ggccagcgcc cgcagctcct cgtcgtcgcg aggatagaca gtgataaact
    12421 tgcccgcctg ggaccgttcg gcgttcttgc tcgtcagctc gatgacccgg cgcatggagc
    12481 cggcgaactt gaacgcacac gaccggccca gcagcacctg agcggcccgg tgcagcacgg
    12541 tcggggcgct cagccaggtg gccgagatgt gcagcttcca gccttgcacc cgggccgggt
    12601 ggctgcgggg ggtgacgtgg caccagtggt cgtcctcgcg cacctgccag ccgtctccgg
    12661 acgcgccggc gagcagcagc gcaagcagct ctcgcagcgg caacgggtcg aggctcgcac
    12721 gcatgccaag accttccggc accttaatgg acgacggctg gacgaccgct ggacgtcgac
    12781 tggacgcgta gactcacgcg agtgactgct gccccggtta tcggatccga ccgggccggc
    12841 tgcccggcag ttgtggtgag gagcccggca tcgtggtgag gagcatcgtg cggcttgaga
    12901 tcgccaccca ggatgtcgag ggtgtccggg tcgcccaggc gcgcggcgcc gaccgggtcg
    12961 agctgtgcca ggcgttgccg gtcggcgggc tcacccccag ccaggggctg gtcgagcagg
    13021 cggtggcgct cggtgtgccg gtgcgggcgc tgatccgtcc gcgcgccgga ggctaccggt
    13081 ataccgccac cgagacggcc acgatggtcc gagatgtggc gacggcggtc gccgccggag
    13141 ccgagggagt ggtggtcggg gcgttgaccg acgacgggct cgaccgggcg gtgctgcggg
    13201 cgctggtcca tgccgcggcg ggggcgccgg tgatcgtcca ccgctgcgtc gatgtgctcc
    13261 tcggccaggg ctgggtggcg ccggccgcgc tggtggcgca gctactcgag ctgggcgtgg
    13321 ccgggatgct cacctcgggt ggggcggagc gggccccgga tggccgggac acgatcgccg
    13381 cgctggccgc ggccgccgcc gggcggttgg agattgtggc tggtggcggg gttcgccccg
    13441 agcacttcgc ggcgctggcc cgggccggtg cggacaccgt ccacctcagc gccggccggg
    13501 cggtgagcgc cggcccgtcc gggcctggcg gcggcgagga tgagttcgtg accaccgacc
    13561 cagcggtggt cgccgctgcc cgcgccgcgg tcgacgcgct cacctgacgg gcggccaggt
    13621 gcggccgggc ggcgggcggg gcgagtcctc agtcgaccga ttcggccccg agttcccaca
    13681 ccaccggtag cccggcgccg gccccgtcgg tcgagtagtc atggctgacc gccaacagtt
    13741 cggccatccg gtcctgccag gcgatgttga ccggcagctc caccagggac gcgagcagcg
    13801 cgccgtagtc gtcgcattcg atgacatgga agaggtcctg gccgctgcgc cagatggtcc
    13861 agctggtggc gccggccgcc cggatcgccc ggaccaggtc ggcgggcact tcccggtggg
    13921 cggcgtcgta gtcgtcttcg cggccggcct tgacccgggt gtgtagggcg acgcgcatag
    13981 tcaccgtcct ccttctggtt gctccgtggt ggcgacgcgc cacaccgggc cgtccggata
    14041 ggagtgttcg gcgaccgacc gctccgtgag tcggccgccc atcccggggg cggtgggcgc
    14101 ctggtatcgc ccggccacga tgcgtaccgg gtcggtgaag tgttcgtgga ggtggtcgac
    14161 gtactcgatg gctcggtcct gcatggaccc ggagatcgcc acgaagtccg ccatcgccag
    14221 gtgctgcacc agctcgcaga gaccgacccc gccggcgtgc gggtagaccg ggacgccgaa
    14281 cttgtgggcc agcagcagga tcgccaggtt ctcgtcgacg ccgccgaccc gggtggcgtc
    14341 gatctggatc agatcgaccg cctcggcctg caacagctgt ttgaagacga tccggttctg
    14401 ggtgtgctcg ccggtggaga tgggaacctg gacgccgcgc cggatagcgg cgtgcccgag
    14461 gatgtcgtcc gggctggtgg gctcctcggc ccaggccagg tcgaagccgg ccagggcggt
    14521 caaccagtcg acggcttcgg ccacatccca ccgttggttt gcgtccaccg ccagccgcac
    14581 ctcaggtccg accgtcgccc gcgccacccg cagccgtcgt aggtcttcgt cgaccgcgcg
    14641 ccccaccttg agtttgatgg tgcggtagcc gtccgcgacg gcgcttcggc acagcgcggc
    14701 cagcttgtcg tcggagtagc ccagccaccc gggtgaggtg gtgtacgccg ggtagccgcg
    14761 ctcggccaac tcggctcgcc gggcgtcccg gctggccagg ttggcggtca gtatcgcccg
    14821 ggcctcgtcg ggggtgagcg cgtcggtgag gtaacgccag tcgatgcacg ccacgatctc
    14881 gtctggggtc aggtcggaga tgaaccgcca cagtggtttg ccggcgcgcc gggcggccag
    14941 gtcccaggcg gcgttgacca cgccgccgat cgccatgtgc atgacgcctt tctcggggcc
    15001 gagccagcgc agctgcgagt cgccggtgag ccggcgggcg aacccgccga ggtcggcgca
    15061 gagctcgtcg aggtcggtgc cgaccacgtg gtcgcggagc gcgtcgacgg ctgcggtctg
    15121 gacgtcgttg ccgcggccga tggtgaacac cagcccgtac ccgcccagtg gttcaccatc
    15181 cgatgtcgac tcgtcggtcc gcagcacgac gtacgcggcg gagtagtccg ggtccgggtt
    15241 catcgcgtcg gagccgtcga gctgccggga ggtggggaat ctgaggtcgt gggtgtcgag
    15301 cgccttgatc gtcgccattg gccggcctac ctttcctggc tggggacgag gccgggggtg
    15361 cggcggtcgc gcggcggcac cactacggcg gtcaggtccg ggtcgggcat gtccgggtcg
    15421 aacgggaaca tcggccgttg gatgtcgttg tgccccaggc gcagcaggtc ctggtccacc
    15481 ccgcccgggg tcagcagcag ccgccagtcc gccgccaact cgtacaggta cggctcaagg
    15541 tagccgatct ttacgaccac gatgtcggcc tgcgccgggt cgatgccggt gtgggagaag
    15601 tcctccgccg tgtggtacgg cttgcgccgc tcggtgacga tcacgcgcag cccaccgacg
    15661 gcgacgaccg cgaccgtccc ggccaccggg tcggtggtcg agacgtgtgc gaccgtgccg
    15721 gtcagcgtca ctggtccctg gtgccggtcg tcgacccggg ccccgacggt gatcgacacg
    15781 tcagcggcca cgccggccgc cgccgcggcc cgggcgccgg cggcgtcggg gatggcggcg
    15841 tagaccccgg tgagctcgcc ggtggcgaac gcggggtgtg ccaacagccg ggcgagggtc
    15901 caggtgacgt ccgcggcgcc gccggcggtc gggttgtcgc cggagtcgga gaggacgaac
    15961 gggcgggccg ggctggcgag cgcttcggcc aggcattcgt cgagcgttcc ggccggcgcg
    16021 acgaaactga actcggcccg agcctgccag tacgcgcggg ccagccgctc cgcctgctgg
    16081 ctggccaact ccgggtcgtc gccggtcacg acgacggcgg ctcggcagcg cggctcatcc
    16141 gcccaggcgt acccgaccca gatcgcggcg tcgagcactc cgtcgagcgc ctcgaccttc
    16201 ggcacctcgg cgtagatgcg gctggccggc tcgactcggg tcgaggtctt ctcgccgggc
    16261 agcagcaccg ggaccggcac ccacgcctgg tgtggccgcc ggccggagtc gaggcggtcg
    16321 agtaggttgc gaacgctgcg ttcgcgggac tccatcgcgt cttcgtgggg cgccatccgg
    16381 tagcaggtga tcaggtcgac cgcgtcgagc agctgccggg tgacgttgcc gtgcaggtcc
    16441 atcgaggccg agaccatcgc cgtcgggccg accacctcgc gtacccgggt ggccaggccg
    16501 ccttcggcgt cggtctgtgc ttcgaccgac atggcgccgt ggatgtcgaa gaaaacgccg
    16561 tcgaatgggc cgtgggccgc gagcaggtcg agggtcgccc gctccagctg ctggtaggtc
    16621 tcggcccgga cggcgccgcc ggggatcgac cgggcctgca tcagcggcac ccactcggcg
    16681 cgttcccgta gcggctgccc gggtgtgagg aacgggtagt aatcgagcag ctccgtgccg
    16741 cgccgtacga cgaagtctgc caggccggcc cggtgcgggg agaaggtcga ggactcgatc
    16801 gcgataccga cgatggcgac gcgggggagc ggggtggcac ggctactcat ggggtccttt
    16861 cggctgcgct gtcggcgaag gcggcggtga gggcgagtcg accggcgccg atgacgccgg
    16921 cgtcggcccc ggtgcgggtg ggttcgatga ccaggtcgcg ggtggccagc gggtggcacc
    16981 cctcgtagag ctggctgcgg acggccgcca caaaaggctc gagtgtggac agtgccccgc
    17041 cgaggtagac cgcgccgggg ttgacgaagt tgacgaccgt gctcaggact tcgccgaggt
    17101 gcctgccggc ggagcggacc aggctcatcg cctgggcgtg accttggcct gcgaccgtca
    17161 ccagctccgg ggtgccggag accgccaccc cgcgttctcg cagtagccgg atgattccgg
    17221 cggcgctggc cacggtctcc aggcagccga ggttcccgca ggagcacggg gtgtcgccgg
    17281 cgctggcgac ccgggtgtgg gtgatgtcgc cggcgttgga ggtggagccg cggtagatgc
    17341 gaccgtcgac gatgaggccg gagccgatgg cgctgccggc cttgaccgtc accgagtcga
    17401 agccgtgttc ggcgcgttcg tagtgttcgc cgagggccat ggcgttgacg tcgttctcca
    17461 ccacggtcgg cacgtcgagc tgcttctcca gccagtcgcc caccgggtag ccgttccagg
    17521 tggccagccg ggaggcttgc acgacggtac gcgcctgcgc gtcgaccggt gccgcgagcg
    17581 cgaccgccac ggcccgcagg tcgccgggta cgtcgacacc tagctcactc atggtgctgg
    17641 ctaagctgcg tagcgtgggt tcggggccgg cggtggcgtc gaccgtgagg ttggcgctgc
    17701 ggtcgagccg gccggtgagt ccgatgatcc cgacccgggc gtgatggctg ccgatctctg
    17761 ccacgccgac atagccgccg tggtcgtgca gtcgcagcgt tcgcggcggc cggccgccgc
    17821 gcgaaacccc gtggctgtgt tcgtagagca cgcccgcgtc gaccaactcc tggacgcgta
    17881 gtgacacggt cgagggggag atggcgagcg tgcgcgccag gtcggcgcgc gaggtcgcgg
    17941 ctccggtgga gacgagctcc acgatgcggt gcgtcaccac cggcgatact tccttcgatc
    18001 tcgaactaat ggcacccagt gttgccacct cattactcgc cgctccaatc ctggatctcg
    18061 catcttttcc ctggccaagc cttccctgcc ggccgtggga accctatagt ggcagtgcct
    18121 tggttatgac agtaccgtcg gaacttcgtc cagtccagaa ctaagtctcc actttcggcg
    18181 ccgcggcggc gaggcagggg aggagagcat cactgtgtca cagcaggccg ggtggtttac
    18241 ccatgatcgg ttcgggctat ttgtccactt cgggctctat agtccgctgg cgcggcacga
    18301 gtgggtgatg acccgcgagc agaccccgcc ggaggagtac gagcagcacg ccccgttctt
    18361 cgacccggac cggttcgacc cgcgcgcgat cgcgcgggcc gccaaggacg cgggcatgcg
    18421 ctacgtcgtc ctcaccgcca aacaccacga gggcttcgcg ctgtgggaca ccgcgctgtc
    18481 ggagtacaac gccaccaagg tgaccggccg ggacctggtc cgcgaattcg tcgacgcggt
    18541 ccgcgccgaa ggcctgcggg tgggcctcta cttctcgctc atcgactggc accaccccga
    18601 cttcacgatc gactaccacc atccgctgcg taacctgccg gacgcccggg aacgcaacca
    18661 gcaccgcgac atggcccgct accgggaatt cctccacggc caggtgggcg agctgctgac
    18721 cggctacggg aaactggact acctcttcta cgacttcacc tactctgaac cccgggacgg
    18781 ttgggagggg aaggggccgc aggactggga cgccgagcgg ctgctcgcga tgacccgcga
    18841 gctccagccc ggcatcgtcg tgaacgaccg gctcgggatc cccgccgacc tggtcacccc
    18901 cgagcagtac cagccggacg cgccgatgcg ccgcgacggc cgggacgtgg tgtgggaagc
    18961 gtgccagacg ctcaacggct cctggggcta cgaccgggac aatctggact tcaagtcccc
    19021 ggacctgctg gtgcggatgc tggtcgacac cgtcgccaag gacggcaaca tgctcctcaa
    19081 cgtcgggccc gacggtcgtg gcgcactcac cccacgtgac caggagagct tggcggcgat
    19141 cggccggtgg atggagctgc acggtcgctc ggtggtcggt gccggcgccg ccggcctgcc
    19201 cgcgccgccc ggcaccgtgc tcacccgccg cggcgaccgg ctctacctgc acctcctggt
    19261 ctggccgttc ggccacctgc acctgcccga gctggcccac cgggtgcgct tcgcccggtt
    19321 cctccacgac ggctccgagg ttcgtcgcag ccagatcgac cctggccagc aggcatggaa
    19381 caccgtgccg ggcggacagc cgccgggcac cctcaccctc cacctgccca ccgcgcgacc
    19441 cgcggtcgag gtacccgtca tcgagctcgt gctgaccgac gagtgactcg cccgggtcgc
    19501 aaccccgaga cagcacccaa ccccaaccca gagtgaggaa gaaaatagag atgagaaaca
    19561 gaacgcgaac cgcggtggcg gccgctgccg gcgccgcgct gctcctggcc gccggctgtg
    19621 gcgacagcgg cggggacggc gacggcacgg tggtcttcga catgtgggcc ggcggcgacg
    19681 acgaggtcga cgccctgcgc gcccaggtcg agatcgccga ggaagagacc ggggtcgaga
    19741 tcagattacg gacctcgccg tggaacgatt tcttcaccca gctgaccacg cgcgcatcct
    19801 ccggtgagat ggcctgtctc accgggatga acggccagcg gctcggcgac tacgccgacg
    19861 ccttcctgcc gctgggcgag gaagagttgg ccaccgcggg gatcgacccg gccgacttca
    19921 ccgagggctc gctggacatc atgagccacg aaggaaacct ctacggcatt ccgtacgacg
    19981 tggcgaccat gatcgtctac tacaacaagg acatgctcga cgaggccggg gtgcccgaac
    20041 cagctgccgg ctggaccttc gacgacttcg aggacaccat cgctggcgcg accaccgacg
    20101 cccagccggg cttcggcgtc ggcatggccg agttccagtg gatgtcgttg ccgatcgcga
    20161 ggtcgggagt ccagccggtg accgaggacc ggcagctcga cctgaccaac ccggcgttcg
    20221 tcgaggcgag cgagtggtac ttcggcctgg tcgacgaggg ctacgcggcc gtgccagggt
    20281 cggcttcgga caccggatgg ggcgaggagc agtaccagaa cgccaacacc gccgtggcgc
    20341 tggacggcac ctggaacgcg gtgacgtacc tgaacaacga cgccggcttc cgcgccggca
    20401 tggtcgagct gccgagccag ggcggcgagc ggctcggcct ggtcctcggc tccggctacg
    20461 ggatcagcgc tgactgcgac gacccggaga ccgcgctgca ggtgctcggt gcgctggtgg
    20521 gggaggccgc gcaggatgag gtcgcctcgt ccgggcgttc ctacccggcc cgcagttcct
    20581 cccagccgct ctacttcgag gcgctcgacg acgagatccg cgacgaggtc gaggccgcct
    20641 tcgaggctgc cttcaccgac ctggaagggc agtactccac cgacaactgg acccagatca
    20701 acgaggcgat ccagccgaac ctgatctccg tctacgcagg ccagatgacc cccgctgagc
    20761 tgctggagca gacccagcag cagttcggcg ggtgaccgag cgtgagtgcg aagctgtgac
    20821 tacgctgacc ggctcgacga aacgtcggcg cggcggcaat cagctgcggc ggatcgagac
    20881 tcgccaggcg ctgggcttca tcagcccggc cctggcgggc ctcgccctgt tcaccgcctt
    20941 ccccgtcgtg ctctcgatcg cgatgagctt ctaccagtgg cccgccatcg gtgagcgcga
    21001 gttcgtcgga ctcgacaact acgtcaacct gttccagaac caccccgact tcattccggc
    21061 gctgcggaac acgatcgtct tcacgttgtt gttcgtaccg ctgaacctgg tcgtgtcgct
    21121 gacgctcgcg ctcgcgctgg cgccgcggat ccggggacgg gcagctttcc gggtgctgtt
    21181 cttcctgccg gtggtcacac cgatcgtggc gaacgtgctg atgtggaaga tcctgctgca
    21241 gcccaacggg ttgctcagcg gcgcctcctc gtcgctgttc ggggtgaccc tgccgaactt
    21301 cctcgcccac cccacctggg cgatggtcat ggtggtggtg atgtcggtct gggccggcat
    21361 gggctacaac atgctgatct tctcggcagc gctggagcag ctgccggagt cggtgctgga
    21421 ggcggcccgg atcgacggcg cccacgggta ccggatgctg ctgcgggtga tcgtgccgct
    21481 gatctccccg gcgatcttct tcgccacggt catgaccatg atcactgcga tgcaggtctt
    21541 cgcccaaccg cagctgctca ccggcggcgg ccccggcaac tcgacgatgc cgctggtgat
    21601 gttcatctac aaccaggcgt tcacgttcca gcagatgggg ttggctgcgg cggcggcgtg
    21661 gattctgttc gccttcatca tcacgctcac ggccgtccag ttccgtgcgc agaagcggtg
    21721 ggtgcactat gaggtctgat gtggtcgaag cgaaaggcgt cggcgtggcg ccggtccggg
    21781 gcgggcacgg cgtcccccgg cgcgacaccg gtcggagcac cgcccgttcg gtcctggccc
    21841 acaccttcgt ggtcatcgcc gcgctcatct tcgccacccc gctgatctgg gcgttcttct
    21901 ccgcgctcaa gccgaaccac gagatgttcg cttcgccgcc gagcctgttc gcctccgagg
    21961 tccgatggag caactttctt gaggtcttcc agtatggacc gttcgtcacc tacatccgga
    22021 actccttcct gatctcggtg gccggcaccg tcctggtact ggtggtgtcg gcctgcgccg
    22081 ggtacgcatt cgggcggctc cgctggcggg ggcgggacct ggtgttcatc atcttcctcg
    22141 ccacactgat ggtgccgcag gaagtcctcg tggtcccgat gtaccagctg atgctgtggt
    22201 tcggctgggt caacaccccg cagtcgctgg tgttgccgtt cgccttcacg gccttcggca
    22261 ccttcctgat gcgccagttc ctccgcggaa tcccctttga acttgaggag tcggcgcggg
    22321 tggacggcgc cgggccgctg cggacgttcc tgttcatcat cctgccgttg gcccggccgg
    22381 cgttggcggt gctgaccgtc ttcaccttca tcagcttctg gaacagctac ctgtggccac
    22441 tgatcgtcat ctccgactac ggttcactcg gcaccctgcc gatcggcctg gcgaccttcg
    22501 ccggtcagtt cggcacccgg tgggacctgc agatggcggc gacgattatc tccatgatcc
    22561 cgaccaccct gatcgtgatt ctgttgcaga agcacctggt caagggcatc tccaccgcgg
    22621 ggctgggcgg ccggtgaggt cacagcgaac cgcagcgcgt acgtgtgccg gcggcggagg
    22681 tgagcggtga cggccggtgt aaccgtcctc ggtatcgaca tcgg
//
