LOCUS       NZ_CP070496            22766 bp    DNA     circular CON 05-MAY-2024
DEFINITION  Natronoglycomyces albus strain DSM 106290 chromosome, complete
            genome.
ACCESSION   NZ_CP070496
VERSION     NZ_CP070496.1
KEYWORDS    RefSeq.
SOURCE      Natronoglycomyces albus
  ORGANISM  Natronoglycomyces albus
            Bacteria; Actinomycetota; Actinomycetes; Glycomycetales;
            Glycomycetaceae; Natronoglycomyces.
REFERENCE   1  (bases 1 to 3937850)
  AUTHORS   Sorokin,D.Y., Khijniak,T.V., Zakharycheva,A.P., Boueva,O.V.,
            Ariskina,E.V., Hahnke,R.L., Bunk,B., Sproer,C., Schumann,P.,
            Evtushenko,L.I. and Kublanov,I.V.
  TITLE     Natronoglycomyces albus gen. nov., sp. nov, a haloalkaliphilic
            actinobacterium from a soda solonchak soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3937850)
  AUTHORS   Sorokin,D.Y., Khijniak,T.V., Zakharycheva,A.P., Boueva,O.V.,
            Ariskina,E.V., Hahnke,R.L., Bunk,B., Sproer,C., Schumann,P.,
            Evtushenko,L.I. and Kublanov,I.V.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-FEB-2021) Bioinformatics, Leibniz Institute DSMZ,
            Inhoffenstr. 7B, Braunschweig 38124, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 06-MAY-2020
            Assembly Method                   :: HGAP v. 4
            Assembly Name :: 871_Haloglycomyces_alkaliphilus_DSM106290
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 620.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016925535.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 05:55:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,443
            CDSs (total)                      :: 3,382
            Genes (coding)                    :: 3,339
            CDSs (with protein)               :: 3,339
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 2 of 43
            Pseudo Genes (incomplete)         :: 40 of 43
            Pseudo Genes (internal stop)      :: 2 of 43
            Pseudo Genes (multiple problems)  :: 1 of 43
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:08:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2422035
            Orig. end                         :: 2444801
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070496.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22766
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="10"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22766
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22766
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12766](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12766)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(225..241)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            complement(379..1671)
                     /locus_tag="JQS30_RS10280"
                     /old_locus_tag="JQS30_10270"
     CDS             complement(379..1671)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JQS30_RS10280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JQS30_10270"
                     /product="hypothetical protein"
                     /protein_id="WP_213170197.1"
                     /transl_table=11
                     /translation="MQEFDWGFEDAIESNLEATLMISREYFPGDWKDVARAAISAGFRR
                     GWIVPGHEDPDFASRYSSMFRPLPGDPDDWSTWIYRNYPSEESPDSVDRFAIIPTAAGR
                     MLDRRYRQAFQSGLIGSSCENIVDGAQITDLAMRSWCTAAGITLPRFEMLDADQQNTVS
                     IEAFAQLTVARVALDTEVRAKHTSDWHNNYTALSTLESFDSHGRLACDAVLGSDMTARI
                     RFPSGVLYPKEDSYGNEGQHDIIRVQISMLLLIARLQHQRLFSRELLELLDWSQDRSHS
                     VHRSILLEALQQLVENGMVEIGDGPDEDPGNNEFTAFPGSPRDWAKWLYESLWVPRHAE
                     KPGPDNYFYLSLTQYGMRAGQHLVNDLLSGSNARDVDLVADEARLVEVLVASWRKFYDN
                     SLMSSRFNFDEYEIKVLIDVALELLILAEDS"
     tRNA            complement(2681..2752)
                     /anticodon=(pos:complement(2424753..2424755),aa:Val,
                     seq:gac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="JQS30_RS10285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="JQS30_10275"
                     /product="tRNA-Val"
     gene            complement(2681..2752)
                     /locus_tag="JQS30_RS10285"
                     /old_locus_tag="JQS30_10275"
     tRNA            complement(2832..2907)
                     /anticodon=(pos:complement(2424907..2424909),aa:Gly,
                     seq:gcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="JQS30_RS10290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="JQS30_10280"
                     /product="tRNA-Gly"
     gene            complement(2832..2907)
                     /locus_tag="JQS30_RS10290"
                     /old_locus_tag="JQS30_10280"
     misc_feature    complement(2907..2920)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.3"
                     /tool="antismash"
     gene            complement(3050..3751)
                     /locus_tag="JQS30_RS10295"
                     /old_locus_tag="JQS30_10285"
     CDS             complement(3050..3751)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010694887.1"
                     /locus_tag="JQS30_RS10295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10285"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_213170198.1"
                     /transl_table=11
                     /translation="MAQIYDTLCTGRPDADFYLDLIMRSRSVLDVGCGTGAFLRAAREA
                     GHPGRLCGLDPSEPMLEVARARGDIEWVCADVSAMHWRQEFDLIIMTGHAFQFLVDDAQ
                     IAGALEAIRRALAEDGRFVFETRNPLRRAWERWTSEYQKEIKGPNGEVIQVRHDLESVE
                     GDTVTFTETMNSASWEKPSLSRSSLRFLDRPSLAQFIADAGLKVDHQYGNFDLRPFEDD
                     DDEIITVASRK"
     gene            complement(3783..4514)
                     /locus_tag="JQS30_RS10300"
                     /old_locus_tag="JQS30_10290"
     CDS             complement(3783..4514)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="JQS30_RS10300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10290"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_213170199.1"
                     /transl_table=11
                     /translation="MPDAALERDIAAIYDVLNTWGLDDDFVLDRIKKAQAVLDVGCGTG
                     RVLHGALDAGFTGRLVGIDPDPWALERARVRSEVEWVHGDMSTHTWDREFDLAVMTGNA
                     FQQLVSDEDVTTLLDGVFRALRPGGSFLFGTRDPRAKAWESWSDEPATFTFEGDKVTMS
                     QRVEPPLDKSNIVISIDETMESARWAAPDTRTCQLRFFTLDQVNSLLAKAGFVVAEQYG
                     YWDGRPIDAHSRDIITLAKRP"
     gene            complement(4554..5765)
                     /locus_tag="JQS30_RS10305"
                     /old_locus_tag="JQS30_10295"
     CDS             complement(4554..5765)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="JQS30_RS10305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10295"
                     /product="MFS transporter"
                     /protein_id="WP_213170200.1"
                     /transl_table=11
                     /translation="MTQLITKDLPPVSSTRAATAALAVTIGSVIPVFLLGGLAVQIIAE
                     LSMSATQLGLVVSLYFAVSGVTSILCGRAVEKFGMIAGSYVGIGLAAASLIAVAVFAHS
                     FAVLAILMALAAPANGFGQLAANAILATYGSPQHKGLLFGLKQAAIPMSTMLAGASVPL
                     LALTVGWRWAFIAAAVLSLLAIPQLRGIPARRKNVPASQSERTNPAPAKSVMSPGLILM
                     TVATGVAATGATPTGSFLADYATSIGVSASLAGLNLTLGGLVGVFARTFVGGIADRNGG
                     TNPFSIIVVLLLIGTAGLLTFTLESHWLLPVATILAFAFGWSWPGLLNFGVASLYRHTP
                     AAATGVTQTGVYIGGALGPLGFGLLVDHSGYQAAWVAAAACMLLAAALIETSRRMLRNE
                     NLGV"
     gene            6481..7692
                     /gene="rocD"
                     /locus_tag="JQS30_RS10310"
                     /old_locus_tag="JQS30_10300"
     CDS             6481..7692
                     /EC_number="2.6.1.13"
                     /GO_function="GO:0004587 - ornithine aminotransferase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (26-346). E-value: 7.5e-105.
                     Score: 342.6. Matches aSDomain:
                     nrpspksdomains_JQS30_RS10310_Aminotran_3.1"
                     /codon_start=1
                     /gene="rocD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851504.1"
                     /locus_tag="JQS30_RS10310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10300"
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="WP_213170201.1"
                     /sec_met_domain="Aminotran_3 (E-value: 5.2e-121, bitscore:
                     401.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSADLIKLEDQHGAHNYHPLPIALAEGEGAWVTDTEGNRYLDL
                     LSAYSAMNFGHRHPRLVEATHKQVDRLTLTSRAFHNDQLGPFAAELAALAGMDSVLPMN
                     TGAEAVETGIKTARKWGYQRKGVAADQARIIVFDGNFHGRTTTIVGFSTDDNARQDFGP
                     FAPGFDIVPYGDAQALEAAITENTVAVLFEPIQGEGGVVIPPAGWLERIRQLCDEHNML
                     MIADEIQSGLGRTGYTFACEREGVRPDVYLLGKALGGGIMPLSAMVADRAVMDVFSPGQ
                     HGSTFGGNPLSAAIGREVVAMLSSGEWQQRSLDLGKHLSNALSQIDPNLIKEIRVCGLW
                     AGVELSEAAPPAREVCERMAKAGVLCKETHSTTIRIAPPLVITPEELDHAVDVLKEALS
                     QLEV"
     aSDomain        6559..7518
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JQS30_RS10310_Aminotran_3.1"
                     /evalue="7.50E-105"
                     /label="JQS30_RS10310_Aminotran_3.1"
                     /locus_tag="JQS30_RS10310"
                     /protein_end="346"
                     /protein_start="26"
                     /score="342.6"
                     /tool="antismash"
                     /translation="AEGEGAWVTDTEGNRYLDLLSAYSAMNFGHRHPRLVEATHKQVDR
                     LTLTSRAFHNDQLGPFAAELAALAGMDSVLPMNTGAEAVETGIKTARKWGYQRKGVAAD
                     QARIIVFDGNFHGRTTTIVGFSTDDNARQDFGPFAPGFDIVPYGDAQALEAAITENTVA
                     VLFEPIQGEGGVVIPPAGWLERIRQLCDEHNMLMIADEIQSGLGRTGYTFACEREGVRP
                     DVYLLGKALGGGIMPLSAMVADRAVMDVFSPGQHGSTFGGNPLSAAIGREVVAMLSSGE
                     WQQRSLDLGKHLSNALSQIDPNLIKEIRVCGLWAGVELS"
     misc_feature    complement(7802..7815)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.17"
                     /tool="antismash"
     misc_feature    complement(7915..7929)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.51"
                     /tool="antismash"
     misc_feature    complement(7981..7993)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.62"
                     /tool="antismash"
     gene            8043..8759
                     /locus_tag="JQS30_RS10315"
                     /old_locus_tag="JQS30_10305"
     CDS             8043..8759
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="JQS30_RS10315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10305"
                     /product="response regulator transcription factor"
                     /protein_id="WP_213170202.1"
                     /transl_table=11
                     /translation="MTPPSAFTAPLFNEEDTFIQPPATHSPTHTVSITGHPMFVAGLEW
                     LVNASKQLRVVSSFTGRDLTSSLRKSRTADAAVVDFDYHSGVSGSLLRKLYAENTNLIV
                     FSAGADWARVQEAIGWGAIGYIDKCASPEQILTAIHLVAGGSAVFSPHLATQVTSRLQQ
                     STETASFPNLTPRENEVLALVATGMDNFQIAKQLGVSRKTVRNHLSHLLAKLGVASRSE
                     AIARAHDAGMGTSDFG"
     gene            complement(8763..10004)
                     /locus_tag="JQS30_RS10320"
                     /old_locus_tag="JQS30_10310"
     CDS             complement(8763..10004)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="JQS30_RS10320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10310"
                     /product="MFS transporter"
                     /protein_id="WP_213170203.1"
                     /transl_table=11
                     /translation="MTDTSTYRSRVGALRANRDFGKLWIGQGVAELGGSISMLAIPLLA
                     IAMTGNEVMAGLMGTAGFVAMWLAHLPAGYIADMFDRRKIMLWCQGTQSFLYGGFIIAL
                     VTGYASVWALMAVYMAACVLAIVFGAAQRQAIRQIVDRDHIPEAISMSTARGYAISMAG
                     PSIGGGLFAVARSAPLIADVVTNLISMLFVSRIKTSLKPESKPTIGRLLPDIGTGWKVL
                     WTNTFLRSKTIYSVTTNVAVSALMFVLIIDNASDSVVLGASLSAAAGAGLVGALIAPFL
                     YRRLGMRTLIVGSALVRGSVLVVAAWSGSPILFAAVLATVMLLGPTVNTALSAATLLAV
                     PKEVLGRASSSSAFVSSALQPFAPLLAGLMLYFLSTAATQLVIAGAFVFVALLAATLPG
                     LDVRPGSQPREAKA"
     gene            complement(10001..12766)
                     /gene="lanKC"
                     /locus_tag="JQS30_RS10325"
                     /old_locus_tag="JQS30_10315"
     CDS             complement(10001..12766)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="JQS30_RS10325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10315"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_213170204.1"
                     /sec_met_domain="micKC (E-value: 3e-127, bitscore: 423.4,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.9e-14, bitscore: 50.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.8e-29, bitscore:
                     98.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYAMETLYIYCLQHPRWFDSLSRYVPGGDHLAVYRDTMPRDWGLR
                     RRGLWFIADPPQGRLKAQGWKLHLSTRTEDSVRMLREALPILRDHGAQFKFLLDPKAVS
                     MVNGKIWPRGSSGKFFTIYPEDDDQFRSLALELSTKLKSFQGPYILSDRRVEGSSVVHY
                     RYGGFAGIPQVRSDGAVNLMIAAPDGTLVPDIRHPYWNAPEWVDVDPFGKPAGDIVDEN
                     DAGEEELLGGRFDVVEALQFSNRGGVYRAIDSQTGLEVVIKEARPHVQIGSPGMAQECI
                     DVLRKEHRLLAELSDSPYFVTPAAIFDEWEHCFLAEEFVSGNQLSQISISSNPLYTQEL
                     TPEHFSSYYTRMLGMFEQFAAALEEAHAKGIVFGDLSWTNVLVEEDTDRVKLIDLDAAI
                     QIGTDAPLGVHTKGISSPENMRTGVPTAQGDLYALGAMLFGSIMLLNTYLGYRPEALPS
                     FLRELQSDLGVPADFVELISELTDTSQPLRLDAGHVRTRLAAMSITSAENWPETIPLAR
                     PASETFDRDRVEQLRKRTKETVEGISKYLRNTATTERDDRLFPADVGVFETNPLGVAHG
                     ALGVMHVLHHVDGEVSDQLRGWVLERTIKPTGTPPGLYHGLGGISWVLSELGYTDYAKS
                     LLTDIGDNPLLHNDHDVMHGSAGVGMACLKLWHEGGDEHFLDVARSIGDHLASTALKGT
                     VGAYWEATDAEGTVSTPLGYAYGSSGVAMFLLYLYAAGQDEAHLKLGRAALDFELSHAV
                     ELNEFITTFRGDADPDRDAVFRGYWDRGTAGVLTALVRYVAVTGDPELEAWVDRLLPDI
                     CRKYAVLPQLFHGLAGVGNALLDVAQFAARPEAVAEAWRTAEGILLYGIDCPEGIAFPG
                     EQAMRESGDISTGSAGVALFLHRLANSQETVAPNLNFMLDEILPRRVDRT"
     gene            complement(12832..12945)
                     /locus_tag="JQS30_RS10330"
                     /old_locus_tag="JQS30_10320"
     CDS             complement(12832..12945)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JQS30_RS10330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JQS30_10320"
                     /product="class III lanthipeptide"
                     /protein_id="WP_213170205.1"
                     /transl_table=11
                     /translation="MKKILNLQKMPSAATRSSIDAISWSSCDSDSCNKAVQ"
     CDS_motif       complement(12886..12945)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKILNLQKMPSAATRSSID"
                     /locus_tag="JQS30_RS10330_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12832..12885)
                     /prepeptide="core"
                     /locus_tag="JQS30_RS10330_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.70"
                     /molecular_weight="1710.8"
                     /monoisotopic_mass="1709.7"
                     /core_sequence="AISWSSCDSDSCNKAVQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKILNLQKMPSAATRSSID"
                     /leader_location="[12885:12945](-)"
                     /alternative_weights="1728.8"
                     /alternative_weights="1746.9"
                     /alternative_weights="1764.9"
     gene            complement(12984..13100)
                     /locus_tag="JQS30_RS10335"
                     /old_locus_tag="JQS30_10325"
     CDS             complement(12984..13100)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038160.1"
                     /locus_tag="JQS30_RS10335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10325"
                     /product="class III lanthipeptide"
                     /protein_id="WP_213170206.1"
                     /transl_table=11
                     /translation="MKKILKLQKMPSAATRSSIDAISWSSCDSGSCNGQVIQ"
     CDS_motif       complement(13041..13100)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKILKLQKMPSAATRSSID"
                     /locus_tag="JQS30_RS10335_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12984..13040)
                     /prepeptide="core"
                     /locus_tag="JQS30_RS10335_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-2.80"
                     /molecular_weight="1751.9"
                     /monoisotopic_mass="1750.8"
                     /core_sequence="AISWSSCDSGSCNGQVIQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKILKLQKMPSAATRSSID"
                     /leader_location="[13040:13100](-)"
                     /alternative_weights="1769.9"
                     /alternative_weights="1787.9"
                     /alternative_weights="1805.9"
     misc_feature    complement(14384..14399)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 24.05"
                     /tool="antismash"
     misc_feature    14430..14446
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.23"
                     /tool="antismash"
     misc_feature    complement(14661..14677)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.99"
                     /tool="antismash"
     misc_feature    14667..14680
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            14722..16299
                     /gene="dacB"
                     /locus_tag="JQS30_RS10340"
                     /old_locus_tag="JQS30_10330"
     CDS             14722..16299
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0004175 - endopeptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009717464.1"
                     /locus_tag="JQS30_RS10340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10330"
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="WP_213170207.1"
                     /transl_table=11
                     /translation="MRKRFLIYTLPVPLIAATTAAVVLSPSAHADEANQALEETIDSIL
                     EDPRLVGSHASVVVADPETGEVIYDRNGEDRQLPASNVKLLTSAAAIDILGEDYRFDTD
                     VHVDGKVRGSAAIGDLYLRGTGDPTMLQEDYVDLAQQVAATGIKTVTGDLVADDTRFDD
                     TRLGRSWPWDNEQFYYQAQISPLTLAPDTDYDAGTVFVSVTPSDSPDEAPTVTLQPETD
                     YVTIDNTATTVASGGANNLQITRKHATNTIAISGTIPVDANNRNSWTTVWEPTGYATAV
                     FADALKDAGVRVIGDVRLGQEVPEDALTVATHQSMTLEDLMIPFMKLSNNGHSEALVKT
                     IGHEVSGAGTWNAGLAAIADFLADQGVDTSVLSQADGSGLSRQNLVAANEFIDLLSATK
                     DAHWYETWYDSLPIACEGERLVGGTLRSRMCGTPAESNARAKTGSLNGVSGLSGYVTDA
                     DGRDLVFSILLNKYVMPGGVKDIEDQIVIALASFSAEEASAPMPQYSPPASEIDGDLEC
                     SWVKPAVC"
     misc_feature    14726..14737
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.58"
                     /tool="antismash"
     misc_feature    complement(16676..16688)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            17150..17953
                     /locus_tag="JQS30_RS10345"
                     /old_locus_tag="JQS30_10335"
     CDS             17150..17953
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JQS30_RS10345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JQS30_10335"
                     /product="hypothetical protein"
                     /protein_id="WP_213170208.1"
                     /transl_table=11
                     /translation="MSAKWVRADGMVMLWVLEDGIRHACGYDPSPGTAALWVLNAMYEQ
                     ESPIVEETHDEQHRRRLAAGEVEPWRLGDFDERDHPELTVPGGGLGWADHPGPGWKRLR
                     WHQLAERIGDPIVRLGHDTFYPIPSLRSFPSVKRDGSWPASIQPPTEGSLDWESFRALA
                     AVLCEFSGPETVVYAHWCDAITAEEFTVFEGRLADLEALRLLPFSSSPSNIWPADRSWL
                     LYTDWDLWGTKVTGPAELLARLEADDFLETAWLPDYRLMLDRRET"
     gene            18166..18288
                     /locus_tag="JQS30_RS17550"
     CDS             18166..18288
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JQS30_RS17550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_281398347.1"
                     /transl_table=11
                     /translation="MTSPWGDESGVELPDAWLQATVRNAPEFERRIYLFLDRDA"
     tRNA            complement(18942..19016)
                     /anticodon=(pos:complement(2441017..2441019),aa:Val,
                     seq:tac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="JQS30_RS10350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="JQS30_10340"
                     /product="tRNA-Val"
     gene            complement(18942..19016)
                     /locus_tag="JQS30_RS10350"
                     /old_locus_tag="JQS30_10340"
     gene            complement(19113..19580)
                     /locus_tag="JQS30_RS10355"
                     /old_locus_tag="JQS30_10345"
     CDS             complement(19113..19580)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013020004.1"
                     /locus_tag="JQS30_RS10355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10345"
                     /product="peroxiredoxin"
                     /protein_id="WP_213170209.1"
                     /transl_table=11
                     /translation="MTISVGQAAPEFTLKDQNNQEVSLQDFAGDKNVLLVFYPLAFTGV
                     CEGELCGVRDDLDEYQTDDVQVLTVSVDSPFTHKVWAEREGFTFPLLSDFWPHGGVATQ
                     YGVFDADKGISNRGTFVIDKQGIVQFAEMNLPGEPRDQQGWKKALAELSGK"
     gene            complement(19713..20129)
                     /locus_tag="JQS30_RS10360"
                     /old_locus_tag="JQS30_10350"
     CDS             complement(19713..20129)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683041.1"
                     /locus_tag="JQS30_RS10360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQS30_10350"
                     /product="DUF3052 family protein"
                     /protein_id="WP_246497857.1"
                     /transl_table=11
                     /translation="MNTTSSVDEPNPVDQLGITADHEVMEIGYDTDVDTDLRDAVIKTV
                     GELHPDDTTDLMDAVLLWWRDDDGDLVDGLLDARSNLDDDGTVWLLTPKANRAGHIDPA
                     TISEAGPLAGLKATKTIPIEPDWLGIRMRLGKNS"
ORIGIN
        1 ccccccttcg cgcaaaagcg ttagtagcgg aaacgaaagt ataattacgt aatccacaat
       61 cggaaacaaa ccgcgtccga caggcgtaaa atcttgccca ccaataacaa tctctacttc
      121 gacttcgaat agatcatata gcaaagacca ttcatcgata tccccccaat ccactgacat
      181 agattccgga ctccagtccg cacgccacga ctcattcctt gaaaatggaa aaaaattaat
      241 atagtttctt tcctttgtaa tctcattcat aaattacata ctccaaacag gatatgcagt
      301 gatcatccta ccttcaccat caactgctat ctggagaacc ttacgcccag ttgctccaaa
      361 ttccattcca gtcttagttc acgaatcttc cgctaggatc agcagttcaa gagcgacatc
      421 aatcagtact ttgatctcat attcgtcaaa attgaatcga gagctcatca gtgaattgtc
      481 atagaacttc cgccatgatg cgaccagtac ttcgaccaac ctggcttcgt cggccacaag
      541 gtcgacatcg cgcgcattag agcctgacag taggtcatta acgagatgtt gtccagctcg
      601 cattccatac tgtgtcagag agaggtaaaa atagttatct ggtcctggtt tttcagcatg
      661 tcgtggaacc cacaaagact catagagcca ttttgcccag tcgcgcggcg agccagggaa
      721 tgcggtaaat tcattgttac ctgggtcctc atctggccca tctccgatct cgaccattcc
      781 attttccact agttgctgca atgcttctag cagaatagat cggtgcacag aatgagatcg
      841 atcttggctc cagtctagga gttcaagcaa ttctctggaa aacaaccgtt gatgctgcaa
      901 ccttgcaatc aagagcagca tggagatctg cacgcggata atatcatgct gcccctcgtt
      961 cccatatgaa tcctcttttg ggtaaagtac cccacttggg aatcgaatac gcgcagtcat
     1021 gtcgctcccc aatacagcat cacaggcgag tctcccatgg gaatcgaaac tttccaaagt
     1081 actcaacgcc gtatagttat tatgccaatc tgaagtgtgc ttagcgcgaa cctcagtgtc
     1141 gagcgcgact cgtgcgacgg taagttgtgc gaacgcttct atggacaccg tgttttgttg
     1201 atcggcatct agcatttcaa atcgaggcaa ggtgatgcca gctgccgtgc accacgaccg
     1261 cattgccaga tccgtgatct gggccccgtc tacaatgttt tcacacgaag aacctatgag
     1321 gccagactgg aacgcttgcc ggtatcggcg atccaacata cgaccagcag ccgtaggaat
     1381 aatcgcaaac ctatcgacgg aatctggtga ttcctcgctt ggatagttcc tatagatcca
     1441 tgtagaccaa tcatcagggt ctcccggcag tggccgaaac atgctcgaat atcgagacgc
     1501 aaaatcaggg tcctcatgcc caggcacaat ccaccctctt ctaaagcccg ctgaaatcgc
     1561 cgctctagct acatctttcc agtctcccgg aaaatactct ctagaaatca tcaaagtcgc
     1621 ttctagatta gactctattg cgtcttcgaa accccaatcg aattcctgca ttagcatcca
     1681 cagggcgatc tcaccgtgac tgtcgagctc ttcgcacttt ttcactattg tgccaccaac
     1741 ctcatccaat tcactgattc acccaatact tactatatcg cttagttcgc tccctagaac
     1801 ttccacatct tcgccacgct cagcagcgag ctgcatggca agttcctcgc tgtcaactgc
     1861 aagctcatcg tcaaggtatt cggcacaacg gtcgaactca cgaaggtcgt ccggggcttg
     1921 tgcatgtgca ggaacaacca agacagagtg actgttgccg tcacagcgag aattggcagg
     1981 gtagcagcct tcagcggccg ggcataacga atcggctctt gcggggcggg cactatgaga
     2041 ttctccatta agttaatgaa aagggcactg cgcggctgtt ggtggggcac cgcactctcc
     2101 gagccacagt agacggccct ctgctcgccg tcaagcagat ctcttcacac ccacgcacag
     2161 gctcgatcta gtaactaacg tacggctgtc acgagcacac tactttcagc aggtcaataa
     2221 cgcctcgcct caaacagaca acaacatctc actagtcaaa tgtgactctt agcactcttt
     2281 atagaataga tagttcattc attcgcctta atctgacagt gcaccttcca gacggtgcct
     2341 agatgcagtt gcaggttaac gacaaataag gcaccagggc gatagcccca ctgttggcaa
     2401 tatcggcttt agctgcaaca acgaaggaat gcgatcatct atagctggcg aaacctactt
     2461 cgagcaaacg ggcgctttgt agatcgctgc atcgactggc agcagagtcc atgagatagc
     2521 caccgactac acgggacatc aaatgggcaa tgaagtgagc gacagctaat ggaaccgagg
     2581 aagtctgctg taggccgacc cgacttacct aaatgccaac acgcacaaag aaagggacca
     2641 tcgactagat ggcccctcat gctctcttcg agactctgag tggacgatac tgggatcgaa
     2701 ccagtgacct cttccgtgtc agggaagcgc tctcccgctg agctaatcgt ccttatccgg
     2761 cgagccggac ccggggagga tgcctagtgg cagtcccaca ataaaaccca gaccgcgaag
     2821 cctgggtttc gtggagcgga agacggggtt cgaacccgcg acctacacct tggcaaggtg
     2881 tcgcgctacc agctgcgcca cttccgcaaa gtatcgtttg cgaggtttcc ctcgctggcg
     2941 ataccaatac tttaacgtac tcctcttcgg gactttcaag accctccact cccgcgtgac
     3001 gacactatta tcgcagctag gaggcccact catgcgctcg tgatatgggt tacttccggg
     3061 aagcgaccgt gatgatctcg tcatcatcgt cctcaaacgg ccgcagatcg aagttcccat
     3121 actgatggtc gaccttcaac cccgcgtccg ctatgaactg tgcaagcgac gggcggtcaa
     3181 ggaatcgcag gctcgagcgg ctgagagacg gcttctccca ggacgcgctg ttcatggtct
     3241 cggtaaaggt gacagtgtct ccttcgaccg actccaggtc atgacgcacc tgaatcactt
     3301 cgccattagg ccccttgatc tccttttgat actcactggt ccaccgctcc caagccctcc
     3361 ggaggggatt gcgcgtctcg aagacaaacc ggccgtcctc agccagcgcg cgccggattg
     3421 cctcaagcgc cccggcgatc tgtgcatcgt cgaccaagaa ttggaacgca tgcccggtca
     3481 tgatgatcag gtcgaactct tgtcgccaat gcatagccga gacgtctgcg cacacccact
     3541 cgatgtcgcc gcgagcgcga gctacctcaa gcatgggttc ggacgggtca agaccgcaca
     3601 agcgtcctgg atggccggct tcgcgggccg cacgcagaaa ggcaccggtt ccacagccca
     3661 catccaagac tgagcgagac cgcatgatca ggtctaggta gaagtccgca tctggtcggc
     3721 ccgtacacaa tgtgtcgtat atctgagcca tgtgcggctc accgtaatag gccataactg
     3781 cttcacgggc gtttcgcgag cgtgatgatg tcgcggctat gtgcgtcaat gggccgcccg
     3841 tcccaatagc cgtactgctc tgcgacgaca aaaccagctt tggcgagcaa ggagttcacc
     3901 tggtcgaggg tgaaaaagcg caattggcac gttcgggtat cgggtgcggc ccaacgggcg
     3961 ctctccatcg tctcgtctat ggagatgaca atgttcgact tgtccaacgg aggttcaacc
     4021 ctctgagaca tggtcacctt gtctccctcg aaagtgaatg tcgccggttc atcggaccat
     4081 gactcccatg ccttggcgcg gggatcacga gtaccaaaga ggaagctgcc gcctgggcgc
     4141 agagcgcgaa aaaccccgtc gagcaaagtc gtcacgtcct catcggatac gagttgctgg
     4201 aacgcgttcc ccgtcatcac cgcaagatca aactctcgat cccacgtatg cgtggacatg
     4261 tcgccgtgga cccattcgac ctcactgcga acccgagccc gttccagagc ccatgggtcg
     4321 gggtcgatac cgactagcct cccggtgaac ccggcatcga gcgcgccgtg gaggacccgg
     4381 ccagttccgc atcccacatc gagtactgcc tgagccttct taatccggtc aaggacaaaa
     4441 tcgtcatcca gcccccaggt attgagcacg tcatagatgg cggcgatgtc tcgttcgagc
     4501 gctgcatcag gcatgcgcac agttttaccg ctgcgccagt tccgcgcaac gtattaaacc
     4561 cccaggtttt cgttgcgcag cattcggcgg ctggtctcga tgagcgctgc ggccaagagc
     4621 atgcaggcgg ccgccgccac ccatgcggct tggtatccac tgtggtcgac caagaggcca
     4681 aagcccagcg ggcccaaagc gccaccgatg tagacaccgg tctgtgtcac tccggtggcg
     4741 gccgccgggg tgtgtcgata caggctggcg actccgaagt tcaacaaacc gggccatgac
     4801 caaccgaatg cgaatgccaa gattgtcgcc actggcagca gccaatggga ttcgagggta
     4861 aacgtcagca gaccggcggt cccgatcaga agcaacacga cgatgatgga gaacgggttt
     4921 gtccccccgt ttcggtcggc gatccccccg acgaaggtac gggcgaatac tccaaccaag
     4981 ccgcccaatg tcaggttgag tccagccagg ctcgccgaaa ccccaatgga cgtcgcgtag
     5041 tcggccaaga aggaacccgt cggtgtcgct ccggtcgccg ccacaccggt ggccactgtc
     5101 atgaggatca gaccggggct catgacgctc ttggccggtg ccgggttcgt tctttcgctc
     5161 tgtgaggcag gcacattttt gcggcgcgct gggatgcccc gaagttgcgg aattgccaag
     5221 aggctcaata cggcggcggc tatgaacgcc cagcgccacc ccaccgtcag ggccaacagt
     5281 ggcaccgatg cccccgccag cattgtcgac atcggaatag cggcctgttt caggccaaag
     5341 aggagacctt tgtgttgcgg ggagccgtat gtggcgagga tggcgttcgc cgccaactga
     5401 ccaaaaccgt tggcaggggc ggctagagcc atcagaattg ccagcacagc gaagctatgc
     5461 gcgaacacgg ccacggcgat caaactcgcc gcagccaggc caattccgac ataggagcca
     5521 gcgatcatcc caaacttctc gacggcgcgc ccacacagaa tggacgtcac gcccgagacg
     5581 gcgaagtaga ggctgaccac cagacccagt tgggtggccg acatcgacag ttcggcgata
     5641 atctgcactg caagaccacc gagcaggaat accgggatga ccgagccgat ggtgaccgcc
     5701 agcgctgcgg tcgcggcacg ggtcgatgag accggaggta ggtctttagt gattagttga
     5761 gtcacggctt ccacgctagg cgagcctgtg ggcttggggt agagctgcca gatgtgacaa
     5821 atgaacactt gcacgggtat ctctttggtg ccatttggcc cctgctgtca catatgttgt
     5881 tcggttttca ttccgctcgg aggtccgagc gggtgaatat acaatcagac cgatgcaatc
     5941 tcatccgtaa aaacgcaggt agaggggcat tttttcctca catcgccact accccggccg
     6001 gagtggtcgt tgcgcgtatg ttgcaatgcc tctacatcgt gagcccaatc gcaccacaac
     6061 gggacctgga ggttcgttga cgccttttgc ctgtgtgacg ctgagccgac cgcagcgcgc
     6121 cgccgcccgc cgtgtgggtg tttcggccgc gcgggtaccg cgccgtgcca gggtgcggct
     6181 tcgcggcgac tccaaggtcc acgtgtgggt ccgtaggcga attttgatgc gtgtcgtcca
     6241 aggtcgcctt gcccgtccgc gatacgatgc ggcactcgtc tgcgctcacc gcgcacagcc
     6301 cgtggccttt tctcgccctg gtcggggcgt cgctttggtc gcggctcgtc ccgcgttctt
     6361 cgcgtacttc cgcgttgtgg cctcgcggcg cgagaatggc ggttttggac gacagcgccc
     6421 acactctctt ttctccacga tgaatcgttt ccgcaatttc gagagcaaga ggatttcacc
     6481 atgacctcat ccgccgacct catcaagctg gaagaccagc atggcgcgca caactatcac
     6541 ccgctgccga tcgcgctcgc tgagggcgaa ggagcctggg tcaccgatac cgagggcaac
     6601 cgttacctcg acttgttgtc ggcctactcg gcgatgaatt tcggccatcg tcaccctcgt
     6661 ttggtggagg cgactcacaa gcaggtcgac cggcttacgc tgaccagtcg cgctttccac
     6721 aacgaccaac tgggtccgtt cgccgccgag ctggccgcgt tggcgggcat ggattccgtt
     6781 ctcccgatga acactggcgc tgaggctgtg gagactggga tcaagacggc ccgcaagtgg
     6841 ggttaccagc gcaagggcgt ggctgccgac caggctcgca ttattgtctt cgatgggaac
     6901 ttccacggcc gcaccaccac gatcgtcggt ttctcgactg atgacaatgc ccgtcaggac
     6961 tttgggccgt ttgcgcctgg gttcgacatt gtcccgtatg gggatgcgca ggcgctagag
     7021 gcggctatca cggagaacac ggtggcggtg ctgttcgagc ccattcaggg tgagggcggg
     7081 gttgtcattc ctccggccgg ctggctggag cgtatccggc agttgtgcga cgagcacaat
     7141 atgctcatga tcgccgacga gattcagtcg ggccttgggc gcaccggata cacgttcgcc
     7201 tgtgagcgcg agggcgtgcg ccctgacgtg tatctgttgg gcaaggccct tggtggcggg
     7261 atcatgccgt tgtcggcgat ggtggccgac cgagcggtta tggacgtttt cagccctggg
     7321 cagcatggtt cgacgttcgg tggcaacccg ctgtcggccg cgattggccg cgaagtggtc
     7381 gccatgttga gttccggtga gtggcagcaa cgctctcttg atctgggcaa acacctgtcc
     7441 aacgcgctta gtcagattga tccgaatctc attaaagaga ttcgggtgtg tggtttgtgg
     7501 gctggcgtgg agttgtccga ggccgccccg cccgctcgcg aggtgtgtga gcggatggcc
     7561 aaggctgggg ttctgtgcaa ggaaacgcac agtacgacga tccggattgc cccgccgctg
     7621 gtcattactc ccgaggagct agaccacgcc gttgatgtgt tgaaggaagc gctttctcag
     7681 ttagaggtgt gatccgagag gggggtgagg gccaagagcc atcacccccc tctcgatatg
     7741 gaagtgtcat atgaggtcag gcgggcttcc gggtttgaag agaatggtga acaagtctat
     7801 gtgcaagcgc ttacatcact ggcggaattt gactacaaac ccagattatg aggattactc
     7861 cggttcagac tccgacatgt cgttgatctg acaggcgacg gtcactaggg cctatagaca
     7921 tgatcttcat cacggtctta gcgtgtctaa gtcggaccca ccccgacgag aatccgcgtc
     7981 gtggcaatgg caccccggaa tgctatagcc actccatcga gccctgaagg atgacgccac
     8041 atatgacccc accctctgct ttcactgccc cactgttcaa cgaagaggat accttcatac
     8101 aacctccagc aacgcactca cctacgcaca ccgtctccat taccggccac ccaatgttcg
     8161 tcgcagggct ggaatggctt gtcaacgcct caaaacagct gagagtggta tcaagcttca
     8221 ccggacgcga cctaacctcg tccctacgca aaagccgcac cgccgacgcc gcagtcgtcg
     8281 acttcgacta ccacagcgga gtcagcggat cgctcttgcg caagctctac gcggaaaaca
     8341 ccaacctcat tgtcttctcc gcaggagccg actgggcccg agtacaagag gccatcggtt
     8401 ggggagccat cggatacatc gacaagtgcg cctcacccga gcaaatcctc accgcgatcc
     8461 acctcgtcgc aggcggatca gcggtcttca gccctcacct agccacccag gtcaccagcc
     8521 gactccagca gtcaaccgaa actgcgtcct tccccaacct caccccacgc gagaacgaag
     8581 tactcgcgct ggtggctaca ggcatggaca atttccagat cgccaaacaa ctgggggttt
     8641 caagaaagac tgtccgcaac catctgtccc acctgctcgc caagctcggc gtcgccagcc
     8701 gttccgaagc catcgctcgt gcccatgacg ccggcatggg cacgagcgat ttcggctagc
     8761 tcctaagcct tagcctctcg cggctgcgag cccggccgga catccaggcc gggcaacgtc
     8821 gccgccagca aagccacgaa gacaaatgcc ccggcaatga ccagctgtgt ggctgcggtg
     8881 gagaggaagt aaagcatcaa tcccgccaat agcggcgcga aaggttgcaa cgcgctggag
     8941 acaaacgcag agctacttga agctcggccc agtacctctt tcgggacagc caagagggtc
     9001 gccgccgaca gcgcggtgtt gacggtcggc cccaaaagca tcactgtcgc caagacggcg
     9061 gcgaacaaaa tcgggctgcc cgaccaagcc gccaccacca gtactgatcc acgtaccaga
     9121 gccgaaccga cgataagggt ccgcatcccc aagcgccggt acaggaaagg agcgataagc
     9181 gcgccgacga ggccggcccc tgcggcggcg ctcaacgacg cgcccaagac cacgctatcg
     9241 gaggcgttgt cgatgatgag gacgaacatc agtgccgaga ccgccacgtt ggttgtcacc
     9301 gagtagatcg tcttcgacct aagaaaggtg ttggtccaca ggaccttcca tccggtcccg
     9361 atgtcaggca gcaggcgccc tatcgtcggt ttggattccg gcttgagtga tgtcttgatg
     9421 cgagaaacga acagcatcga gatcaggttc gtaaccacat cggcgataag cggcgcggat
     9481 ctagccacgg cgaagaggcc accgccgatc gagggccccg ccatcgagat ggcgtatccc
     9541 cgtgccgtgg acatactgat cgcctcgggg atgtgatcac ggtcgacgat ctggcggatc
     9601 gcctgccgct gagcggcacc gaagactatc gccagcacac aggcagccat gtagacggcc
     9661 atgagcgccc acaccgacgc ataaccagtc accagcgcga tgatgaaccc gccgtagaga
     9721 aaggactgcg ttccctgaca ccacagcatg atcttgcgtc ggtcgaacat gtccgcgata
     9781 tagcctgcgg gcaagtgcgc cagccacatc gcgacaaatc ccgccgtgcc catgagaccc
     9841 gccatgactt cgtttccggt catcgcgatc gccaacaagg gaatagccag catcgagatg
     9901 ctgccgccca gttcggcgac gccttgaccg atccagagtt tcccgaagtc ccgattggct
     9961 ctcagggcac caaccctgct gcggtaggta gacgtatctg tcatgttcgg tcaactcggc
    10021 ggggaagaat ctcgtccagc atgaagttca agttcggggc cacggtctct tgcgagttcg
    10081 cgagccgatg caagaagagc gccactcccg ctgagccagt ggagatatcg cccgactccc
    10141 gcatcgcctg ttcgccggga aacgcgatgc cctcagggca gtcgatccca tagagcaaaa
    10201 tgccctcggc ggtacgccag gcctcggcca cggcctcggg gcgggcggcg aactgggcca
    10261 cgtccaacag cgcgttcccc accccggcca aaccgtggaa cagttgtggc aagactgcgt
    10321 acttgcggca gatgtcaggg agcaaacggt caacccaggc ctccagttca gggtccccgg
    10381 tgacagccac atagcgcacc agcgctgtca ggactcctgc ggttccccgg tcccaatagc
    10441 cacggaacac cgcgtcgcgg tcggggtcgg cgtcgcctcg gaaggtggtg atgaactcgt
    10501 tgagttccac cgcatgagac aactcgaagt ccaaagcggc ccggcccagt ttcaggtgcg
    10561 cctcatcctg cccggccgca taaaggtaga gcagaaacat cgctactccg gatgagccat
    10621 aggcataacc caagggggtg ctgacagttc cttcggcgtc ggtggcctcc cagtatgcgc
    10681 ccacagtgcc cttgagcgcc gtgctggcca aatggtcacc aatggagcga gcgacatcga
    10741 ggaagtgctc gtctccaccc tcatgccaca atttaaggca cgccataccc acaccggcgc
    10801 ttccgtgcat cacatcgtga tcgttgtgca gtagcgggtt gtcgcctatg tctgtcagca
    10861 aagacttcgc gtaatcggtg tagcccagtt cggagagcac ccaggagatt ccaccgagcc
    10921 catggtagag accaggcggg gtgccagtcg gtttaatggt gcgctctagc acccatccgc
    10981 gcagttggtc agacacctcg ccgtcgacgt gatgcagcac gtgcatgacg cccagcgcac
    11041 catgcgccac acccagcgga ttggtttcga acactcccac atccgcgggg aacaatcggt
    11101 cgtcacgttc ggtcgtcgcg gtgttccgca ggtacttaga gataccctcg acagtttcct
    11161 tagtacgttt gcgcagctgc tcgactcggt ctcggtcgaa agtctcgctg gccggccgcg
    11221 ccaacggaat cgtctcgggc cagttctccg ccgaggtgat cgacatggcg gccaaccggg
    11281 tgcggacgtg gcccgcatcg agccgcaagg gctggctcgt gtcggtgagc tccgagatca
    11341 actcgacgaa atctgcgggt acgcccaggt cggactgtag ttcacgcaga aaacttggca
    11401 gggcttcggg gcgatagccc aggtaggtgt tcagcagcat gattgagcca aacagcatgg
    11461 ctcccaacgc gtagagatcg ccctgggcgg tggggacgcc agtgcgcatg ttttcagggc
    11521 tggagattcc tttggtgtgg acgccgagtg gggcatcggt gccaatctga atggccgcgt
    11581 ccaggtcgat cagcttcacc ctgtcagtgt cctcttcgac caagacgttg gtccaggaga
    11641 gatcaccaaa gacgattcct ttggcgtggg cttcctccaa agccgcagcg aactgctcaa
    11701 acattcccag catccgcgtg tagtacgacg agaagtgttc tggagtcaac tcctgggtgt
    11761 acaggggatt tgaactaatg gagatttgac tcagctgatt gcccgagaca aattcttcag
    11821 ccaggaaaca gtgctcccat tcatcgaaaa tggccgcggg cgtcacaaag taggggctgt
    11881 cagacagttc ggccaacaat cggtgttcct tgcgcagcac gtcgatgcat tcttgagcca
    11941 ttcccgggga gccgatctga acgtgaggcc gggcttcctt aatcacaacc tcgaggcccg
    12001 tctgcgaatc aatcgcccgg taaacaccgc cgcggttgga aaattgcaat gcctcaacca
    12061 catcgaagcg gccgcctaga agttcttcct cccccgcgtc gttttcgtcg acaatgtcgc
    12121 cagcgggctt tccgaacgga tcgacgtcaa cccactccgg ggcattccag tacgggtggc
    12181 ggatgtcggg gaccagggtt ccgtcaggag cggcgatcat caagttgacc gcgccatcgg
    12241 agcgaacctg cggaatgcca gcgaaaccgc cgtatcgata gtggacgacg ctggagccct
    12301 caacccgacg atccgacagg atatagggac cttggaaaga tttcagcttc gtcgacagct
    12361 ccagtgccag gctgcggaac tggtcatcat cctcagggta gatcgtgaag aacttaccgc
    12421 tagagccacg cggccagatt ttaccgttca ccatagagac ggctttggga tcgagaagga
    12481 acttaaattg tgcgccgtgg tcacgcaaga tgggcaaagc ctcgcgtagc atccggacgc
    12541 tgtcttcagt ccgggtcgac aagtgcagtt tccacccctg ggctttgaga cgcccttggg
    12601 gcgggtcggc gatgaaccac aggccccgtc gacgcaggcc ccaatcccgg ggcatcgtgt
    12661 ctcggtagac cgccaagtga tccccgcctg ggacgtatcg cgacagggag tcgaaccaac
    12721 gtggatgttg caggcagtag atgtagagcg tttccatggc gtacattgac ggtggcctcc
    12781 tcctggcatg aactcgaaag agacccccgt cgcctcaatt aagtccaatg cttactggac
    12841 agccttgttg cagctgtcgg agtcgcagga gctccagctg atggcgtcga tcgaggaacg
    12901 cgtggcagcc gagggcatct tttggaggtt caggatcttc ttcacggtag gtaccgcctt
    12961 tctatgtttg gaaaatgggg ttgttactga atgacctggc cgttgcagct gccggagtcg
    13021 caggagctcc agctgatggc gtcgatcgag gaacgcgtcg cggccgaggg catcttctgg
    13081 agcttcagga tcttcttcac ggtaggtacc gcctttccga ggtgatggtg ctgagtttta
    13141 ctgcggcggg ctgtagctag gagtccagtt tttcgaccag gcgctatgcg tcggggccga
    13201 tttctggacg accatggcaa acaactcgtg caggttgagc tacttccacg cggcggttac
    13261 ctgcttcgat atctcgaatt gggtcaccgc cgcagttaag accttgaggc gatcgggggt
    13321 cgtaagaaag actctggcag tcccggcgcc ccaggcgcat gatcgtttgc caccattggg
    13381 tgcgggaaat tattgggact cacctcccgc ctcgcccggg actaacgccc gagcgtcacc
    13441 tccgagctca ggggaaccgc gacaactgat ttgtttgcgt ggacaggaga gtgagggcct
    13501 gccaggcagc gagtcctagg tgcggaaacg tcctaaaaag acgcgggcac gcatgcaacg
    13561 atgcctaagg cgagccacct tagatggtga gaccatcgaa gtagctgcga gccaggacct
    13621 attgaccggg gagcccgatg cccattgcca tcgcgcggat cttggtacca cgcgctaacg
    13681 taaccgccga agtccccgac gagacatccc ctgtgccgcc ccaagaggaa gccatacgcc
    13741 gaacccgcga aagccgatgg gcatttgccg cagagttcat gcccggccct cttcgggggg
    13801 atgaaatgcc accaggtgtt ttagctgcgc agccgtggcg ggggcaggaa ctccacgttt
    13861 tccgcggcta tgcggcgcac aaccacttcc accggcccat acctagccag ttcagtgacc
    13921 acctcagccg ctagaccaca tgatgcgaac tgggaagccg ctgccgtcgg tgctcagaac
    13981 tggctttggt gtgtgtttgg tggggttggt tcgttgattg ggtgtggcga ggcggtggaa
    14041 tatcgatgat gtgttgtgag gtcggggttg gggatcggct tgaggtgacg ttgcgggacg
    14101 agctccacgt gggggcgatc aagccgcagg tggtgtgtcg ggacagctgg cttgtccgcg
    14161 ccagggaagg gagagctggg gccagctcat cagcatgtgt tagatggtcg tcagtagcat
    14221 tttttggttg ccaaaaggtg ccactatttc ctcaaagagc acgagccatg tggttatacc
    14281 tcagagccga aatctcaggc taataccgac cttggtccac cgcgtatagg aaaaagtacg
    14341 tcgaggctta tgcaaaaggc accttcttcg ttctcttcgg ctcgtttacc tgcgtaaact
    14401 tcgcctcctg cggccttgaa tccgcccttt tgcataagcc tcgtcatgcg ggttcctttg
    14461 cggtcaatct tggccccccg ataggacttt ccctttattc ccgtcgctgt tgaggaccat
    14521 tcctcatttc cgcagaggct ccaccggcca cacctttatg tctgctgccc cttccctgcc
    14581 tcgccgggtg gagatctgcg ctccagggcg gtggaacaaa aattttgacg tgagcagggt
    14641 cacgaaatat gcccaaacat ggcataattt ttcatcaaac ccctacatca taaaaatctc
    14701 cttcaacaag aggacggacg catgcgaaaa cgcttcctca tctataccct cccggtgccc
    14761 ttgatcgccg cgacaaccgc agctgtggtg ctctcgcctt ctgcccatgc cgacgaggcc
    14821 aaccaggccc tggaagaaac cattgactcc attctggaag atccacgttt ggttggctcc
    14881 cacgccagtg tcgtagtggc cgacccggag accggcgaag tcatctacga ccgcaacggc
    14941 gaggaccgcc agttgcccgc atccaatgtc aaactcttga cctcggccgc cgccatcgac
    15001 atcctcgggg aggactatcg gttcgacacc gacgtccacg tcgacgggaa ggtgcgaggc
    15061 tccgcggcaa tcggtgacct ctacctgcgt ggcaccgggg accccaccat gctgcaagag
    15121 gactacgtcg atttggccca acaagtggcc gcgacgggaa ttaagactgt caccggggat
    15181 ctagtcgccg acgacactcg attcgacgac acacgactgg gccgttcctg gccttgggac
    15241 aacgagcagt tctattacca agcgcagatc tcgccactga cgctcgcgcc agataccgac
    15301 tatgacgctg gtaccgtctt tgtctcagtg accccctcgg actcccccga cgaggcaccc
    15361 acggtgactc tccaacccga aactgactac gtcaccatcg acaacacggc cacaacagtc
    15421 gcctcgggcg gcgcaaacaa tctgcagatc acccgcaagc acgccacaaa caccatcgcc
    15481 atcagcggca caatccccgt tgacgcgaac aacaggaact cctggactac ggtatgggag
    15541 ccaactggtt atgccacggc ggtctttgcc gacgcgctca aggacgcagg cgttagagtc
    15601 atcggagatg tgcgactggg ccaggaagtg ccagaggatg ccctcaccgt cgcgacccac
    15661 cagtcaatga ctcttgagga cctcatgatc ccgttcatga agctgtcgaa caatggccac
    15721 tccgaagctc tcgtcaagac catcggtcat gaagtctccg gagctggcac ctggaacgcg
    15781 ggcttggcag ccatcgccga tttcctcgcc gaccaagggg tcgacaccag cgttctcagc
    15841 caagctgatg gatcgggcct gtcccgccag aacctagtag cggccaatga attcattgat
    15901 ctgctgtcgg ccacaaaaga cgcccactgg tatgagactt ggtacgactc tcttcccatc
    15961 gcctgcgaag gagagcgtct ggtcggcgga actctgcgta gtcgtatgtg tggcactccg
    16021 gccgagagca acgctcgggc taagaccggg agcctcaacg gcgtcagtgg cctgtccggc
    16081 tatgtgaccg atgcggacgg acgtgaccta gtcttcagca tcctattgaa caagtacgtc
    16141 atgcccggag gcgtcaagga catcgaggat cagatcgtga tcgcgctggc ctcgtttagc
    16201 gccgaggagg ccagcgcgcc gatgccgcag tactcaccac cggcctctga gatcgatggc
    16261 gatctggagt gcagttgggt caagcccgct gtttgctaga ggcaggcgct caacgcgctg
    16321 cttagctgta gcccaccggg tatcgaccac agtgagtatc ggccatcgca atgtcgtcga
    16381 tgctcagtag cttgctgact ttcgacacga aaatgcccct caacgggttc ccgttgaggg
    16441 gcatttgtgc tggtggacct ttcggtctct tattacaact caaaactcca gtttaaagcc
    16501 tcaattgccc ggctcagaga cctcgtcgta gccatggcgc accatgaggg accccacacc
    16561 acaactcaat tgccccaacg cgcacacggc agccgcgacg gtccaccccg agcaatccag
    16621 accacctcac gcctgaggaa tacgagccac tagtggaggc ggctcgtgct gatgtctgca
    16681 aattgcatct cgccgccgag ttcgacatca gccgccgcaa cattcaccgg ttgttgatac
    16741 gggactgatt cgacagtccg tggatagcct gcctggtatt tggtgcatcg atgcggaagc
    16801 tgagggactc ggcggtctac ggtcaggact ggctctaccg attgttactg gaggctcctt
    16861 ggagatgaca agtctcatcg ctgctttcgt caacgcctca cctcgtgtag gtactcagtt
    16921 ggaggaggtc gcccggatcg tcaaggattt ccaggatcga gacaccggga aggattcgga
    16981 taacgagccg gaattccggc ccgtcgaggt cggggttctg accgagtctc gagtgcatag
    17041 gtgagctcgg ctcggcgaag ggctcgagcc gagctcagac cgcaaccagt agaatcctcg
    17101 caaccgtgat tcggccattc gctatatgtg tgagttcgaa gggatcgtta tgtctgccaa
    17161 gtgggttcgg gccgatggca tggtgatgct gtgggtgctt gaagacggga tccggcatgc
    17221 gtgtgggtat gatcccagcc ccgggacggc cgcactgtgg gtgctcaacg cgatgtacga
    17281 gcaagaatct ccgattgtcg aagagacgca tgacgagcaa catcggcgcc gtttggccgc
    17341 cggagaggta gagccgtggc gcctgggcga cttcgacgaa cgcgatcacc ctgaactgac
    17401 ggtgccaggt ggtgggctcg gttgggccga tcaccccgga ccgggctgga agcgcctacg
    17461 ttggcaccag ctcgccgaac gtatcggcga cccgatcgtc aggctcggcc acgacacgtt
    17521 ctatcccatt ccttcgctcc gttcgttccc gtcagtaaag cgtgatggct cgtggcccgc
    17581 ctcgattcag ccgcccactg aaggcagcct cgattgggaa tccttccgcg cccttgccgc
    17641 agtgctgtgt gagttctccg gccccgagac ggtcgtgtac gcgcactggt gcgatgcgat
    17701 cactgccgag gagttcacgg tatttgaggg ccgtctcgcc gatctggaag cgcttcggtt
    17761 gctgccgttt agctcgagtc cgtcgaacat ctggcctgcg gatcgatcat ggttgctgta
    17821 caccgactgg gacctctggg gtactaaggt caccggccct gcggaactgc tggcgcgact
    17881 cgaagccgac gatttcctgg agacagcctg gctgcccgac taccggttga tgctcgaccg
    17941 cagggagacc tgaccgatgg atcgggcctt cgccgaacgg tgggagcatc gctggtcgaa
    18001 ggatcggccc tgggaaaccg agcggctcaa gttcgcctag aacgaattct gggtccggtt
    18061 ccacaacctg cccgaaaccg agcggtatac cgaaaacgaa ggcgagtaca cccccatact
    18121 ggagcgtcac aacgccgtgt ttgaggagct caagagattc tggtcatgac ctccccatgg
    18181 ggcgatgaat ctggtgtgga acttccagac gcgtggctac aggcgaccgt gcgcaatgcg
    18241 ccggagttcg aaaggcgtat ctacttgttc ctagacaggg acgcctagac ccttggcgtc
    18301 ctcattgtcc tgctccgcaa gtatgcagac ttcgagccag tcagagtggt cattgcagat
    18361 gcgtcttagt cgcagctgtt ccacccctat gacttcaggt tggacgtcat cgtccacatc
    18421 tcgacagaac gagacacgca gaaagaccgc caccacgatt gactgtgccc cactcactcg
    18481 gctattgaag cgcctgacca ggcggactaa ccgcttggaa ggggccacat gaggctgcgc
    18541 cattgagaga aaagttcaga ggctagaccg ccgagggcga ccgcgctgaa cgagaggccc
    18601 catcacggtg aaagctgccc ccggccttgc aagaggacag ccctcgctat acccagcacc
    18661 agagatagac gcgccccaac gggaacaacg caatcctgtg aaaggggaag agtgctcctg
    18721 cggagaaaaa catcgcagac ctcgttagcc acgaattacc aacgtgctgc gaaaggttca
    18781 ccgtattcag ctgtgaccgg tcatcacaca cggtgccgaa cttctggacg ctgagttcgg
    18841 tgaagatttc ctcgacggcg tgttgagaag ttcggattcg ccaggctatc aattaggctt
    18901 gcaaatgccc ccgggagtca ctttcccggg ggcatttgtg ctggtgggcg ctactgggat
    18961 cgaaccagtg accactgctt tgtaagagca gtgctctacc gctgagctaa gcgccctcac
    19021 cagaggcgcc ggctgttggc gcgtcaggct caaataggtt acctgaccta atgagcggac
    19081 atcagcgacc ccagccggcg acgtagcgca ggttactttc cggagagttc cgccagcgct
    19141 tttttccatc cttgctggtc gcgcggctcg ccggggaggt tcatttcggc gaactggacg
    19201 atgccttgct tgtcgatgac gaaggttccg cggttggaga ttcctttgtc cgcgtcgaag
    19261 acgccgtatt gggtggcgac tccgccgtgg ggccagaagt cactgagcag ggggaaggtg
    19321 aagccttcgc gttctgccca gactttgtgg gtgaatgggg agtctacgga gacggtcagg
    19381 acttggacgt cgtcggtctg gtattcgtcg aggtcgtcgc ggactccgca cagttctccc
    19441 tcgcagactc cggtgaaggc cagcgggtag aacaccagca ggacgttttt gtcgcctgcg
    19501 aagtcttgga ggctgacctc ttggttgttc tggtccttga gggtgaattc cggtgcggct
    19561 tggccgacgc tgatcgtcat gtatgtgttc ctctcggttg tgtagctggg ttcaaagcta
    19621 cgtcagtgcg tgggtttcgg cgaggcggtt ctaggtctgg tcggtgggcg ggattggctc
    19681 ccggcggtga cggtggccgg tggttgccgg ggttagctgt tttttcccag gcgcatgcga
    19741 atgccgagcc aatcgggttc gatggggatg gttttggtgg ctttgaggcc ggcgagtggt
    19801 cccgcctcgg agatggtggc cgggtcgatg tgtccggccc ggttggcttt gggagtgagg
    19861 agccacacgg tgccgtcgtc gtcgaggttg ctgcgggcgt ccagcaggcc gtcgacgagg
    19921 tctccatcgt cgtcgcgcca ccataggagg acggcgtcca tgaggtcggt ggtgtcgtcg
    19981 gggtgtagtt cgccaacggt cttgatgacg gcatcgcgta ggtcggtgtc gacgtcggtg
    20041 tcgtagccga tctccatgac ttcgtggtcc gcagtgatgc cgagctggtc gaccgggttg
    20101 ggctcgtcga ccgagctggt ggtgttcacc taggtgcctt cccttcactt cgtggtgtgt
    20161 ctcggctctt tgcttgtcct tgaagtggaa gcagagtcga ggtctcttga ggccgagaat
    20221 acgaaatttc cgccatgagt gttggacatt ggtcggctta agtgaactga gagaccccgg
    20281 gtgtcacggg tttatctttg attcgatgcc aaattgagtc attgtctcgt tgtttttcat
    20341 gtcaccaggg gtagattcag gtcaattcat gggcgaggat gggagtttga ctacccggcg
    20401 cccatcaggt gtgtctgccg tcgcaacaaa acgggtcctg tcgcaacgca acgagtagat
    20461 tcaaggcagg atggtaagaa ccaactacag ctataccctg ttgtctaaga acgagggatc
    20521 gcccgtgacc accgataaca accggccggt aatcagtgac ggtttgccac aacttcccga
    20581 cactgatccc gaagaaacct ccgagtggct tgagtcactc gacagcatgc tcgacgagcg
    20641 cgggagttcc cgggctcgtt acctcatgct gaggttgctg gagcgggctc gggagcgcca
    20701 aatcggtgtt ccgggcccta tcagcaccga ctacatcaac tcgattccgc cggagaagga
    20761 accgctcttc cccggcgatg aagcgttgga gcgccgcatt aggcgctaca ttcgctggaa
    20821 tgccgccatg acggtgcacc gcgcgcagcg gcctggcatt ggagtgggcg gccacatttc
    20881 cacctatgcc tcgtccgcca gcttgtacga ggttggtttc aaccacttct tccggggtcg
    20941 caaccatccc ggcggtggag accaaatctt tttccagggg cacgcttccc caggcatgta
    21001 cgctcgctcg tacttggagg ggcgactgac ggagcagcag cttgatggct tccgccaaga
    21061 actgtcgcgc cccgatggtg gccttccgtc ctatccgcac ccgcgtctca tgcccgacta
    21121 ctggcagttc ccgaccgtgt cgatgggcct ggggcccatc ggggcgatct atcaggccca
    21181 gttcaaccgt tacctgcaag atcgcggtat caaggacacg tccgaacaac acgtgtgggc
    21241 gtatctgggc gacggggaaa tggacgagcc ggagtcacgc ggcgcgttgc agcttgccgc
    21301 agaacaaggc ctggataact tgacgtttgt cgtcaactgc aacttgcagc gtctagacgg
    21361 cccagtgcgc ggtaatggca agatcatgca agagctggag tcgttcttcc gcggtgctgg
    21421 ctggaacgtc gtcaaggtcg tgtggggtcg cgagtgggac ccgttgctgg ctggcgatac
    21481 cgaaggcgcg ctggtgaaca tcatgaacac cacgcccgat ggtgacttcc agacctacaa
    21541 gggagagtcc ggcgcgttcg tgcgcgagca tttcttcggc cgcgacccgc gtacgcgggc
    21601 gctggtggag aacatgagcg acgaccaaat ctggggcctc aagcgtggcg gtcacgacta
    21661 ccgcaagttg tacgcggcct accaggctgc ccagaggcgc aacggccgtc cgaccgtcat
    21721 cttggccaag acgatcaagg gctggacact cggttcgagt ttcgaatctc gcaacgccac
    21781 ccaccagatg aagaagctga cgctggatga cttgaaggtc ttccgcgaca acctcaagct
    21841 cgatatcccg gacgcggacc tggaacgtga cccgtatcta ccgccgtact tgaagttctc
    21901 cgaagactcc gaagaatata agtatctgat ggaccggcgg gccgagctcg gtggccccat
    21961 gccagcgcgt tcgaagaccc acatcgcgct gaatctaccc ggcgaagacg cctacaaggt
    22021 cgtcaagcgc ggttcgggta aacaaaaggt cgccacgacc atggcgtttg tgcggttgct
    22081 caaggacctc atgaaggaca aggagactgg gaaacggtgg gtgcccatca ttcccgacga
    22141 ggcgcgcacc ttcgggatgg acgccatgtt ccccacctcc aagatctact caccgcacgg
    22201 ccagaagtat ctgtcggtgg accgggacct gttcttgtcc tacaaggaag ccgagcaggg
    22261 acagctgctg cacctgggta tcaatgaggc cggttcggcg gcggcgttta ccgccgcggg
    22321 cacctcctat gacacgcacg gcgagccgat gatcccgatg tacatcttct attcgatgtt
    22381 cgggttccag cgcactgccg acagcctgtg ggccgctgcc gaccagatga ctcggggttt
    22441 cctcctggga gccaccgctg gccgcacgac gctcaatggc gagggtctac agcacgagga
    22501 cgggcattct ccgcttatcg cggcgacgaa cccggccgtg gttacctacg acccggcttt
    22561 cggttacgag ctggcgcata tcgtgcagga tggtctgcgt cgcatgtacg gggaggatca
    22621 ggagaacatc ttctactacc tcaccgtgta caacgagcca attcagcagc cggctcagcc
    22681 agagaatctc gacgtcgagg gtctgctcaa gggcatttac aagttcgccg aaggtgaagg
    22741 aacggggcca cgagtacagc tgctgg
//
