LOCUS       NZ_CP070483            21611 bp    DNA     circular CON 17-MAY-2024
DEFINITION  Bacillus sp. LJBS06 chromosome, complete genome.
ACCESSION   NZ_CP070483
VERSION     NZ_CP070483.1
KEYWORDS    RefSeq.
SOURCE      Bacillus sp. LJBS06
  ORGANISM  Bacillus sp. LJBS06
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4154362)
  AUTHORS   Lu,J., Wang,B., Fu,P. and Peng,H.
  TITLE     Whole genome analysis of Bacillus subtilis LJBS06, a biological
            control agent and plant growth promoting bacterium isolated from
            grape rhizosphere soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4154362)
  AUTHORS   Lu,J., Wang,B., Fu,P. and Peng,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2021) School of Agriculture and Biology, Shanghai
            Jiao Tong University, Jiangchuanlu, Shanghai 200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v4; CANU v. v1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 273.0x
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016924995.1-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 03:18:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,356
            CDSs (total)                      :: 4,232
            Genes (coding)                    :: 4,124
            CDSs (with protein)               :: 4,124
            Genes (RNA)                       :: 124
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 72 of 108
            Pseudo Genes (incomplete)         :: 51 of 108
            Pseudo Genes (internal stop)      :: 25 of 108
            Pseudo Genes (multiple problems)  :: 35 of 108
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:28:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3766860
            Orig. end                         :: 3788471
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21611
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="10"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21611
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21611
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11611](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11611
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     gene            complement(184..3870)
                     /locus_tag="JQX68_RS19140"
                     /old_locus_tag="JQX68_19140"
     CDS             complement(184..3870)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="JQX68_RS19140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19140"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_147772659.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNFFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQMHQNPLDAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRQTKHDQWKPAVWNEQTGAFAIPQGTMGSRWDG
                     KQKWNLHMIDEETGEAIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYVTTVFDLILANYGVNRGIGEQQAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAATSEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNAALKPSGTKGMSWSIADEYESLKKRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAQDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3936..3951)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3960..3973)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3960..3974
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     gene            complement(4086..4562)
                     /gene="arfM"
                     /locus_tag="JQX68_RS19145"
                     /old_locus_tag="JQX68_19145"
     CDS             complement(4086..4562)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="JQX68_RS19145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19145"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_014665758.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFISGSCDQTPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFITVNATSDIL
                     ILNIPYYVFKKMMSYNPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(4620..4635)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4706..5425
                     /locus_tag="JQX68_RS19150"
                     /old_locus_tag="JQX68_19150"
     CDS             4706..5425
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="JQX68_RS19150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19150"
                     /product="YwiC-like family protein"
                     /protein_id="WP_147772660.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGIVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQIKPYQKWMCYYGFPACCFLMIPLFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGLASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFFAVMCLFMTR"
     gene            complement(5457..6173)
                     /gene="fnr"
                     /locus_tag="JQX68_RS19155"
                     /old_locus_tag="JQX68_19155"
     CDS             complement(5457..6173)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="JQX68_RS19155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19155"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_014665760.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKNDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKQGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6272..7459)
                     /gene="narK"
                     /locus_tag="JQX68_RS19160"
                     /old_locus_tag="JQX68_19160"
     CDS             complement(6272..7459)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="JQX68_RS19160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19160"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_147772661.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMISFILLLFPVFWISIANSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKATVQ
                     MYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLSPADAGLRTAGFIAVSTLLRPAGGFLADKISPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKMHTERNSQSIN"
     misc_feature    complement(7524..7539)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7594..9264)
                     /gene="argS"
                     /locus_tag="JQX68_RS19165"
                     /old_locus_tag="JQX68_19165"
     CDS             complement(7594..9264)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="JQX68_RS19165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19165"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_069838507.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQLPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELDKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEAIRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLTP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9261..9689)
                     /locus_tag="JQX68_RS19170"
                     /old_locus_tag="JQX68_19170"
     CDS             complement(9261..9689)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="JQX68_RS19170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19170"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_040081525.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLGEENGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="JQX68_RS19175"
                     /old_locus_tag="JQX68_19175"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="JQX68_RS19175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19175"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 9e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="JQX68_RS19175_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="JQX68_RS19175_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10240
                     /locus_tag="JQX68_RS19180"
                     /old_locus_tag="JQX68_19180"
                     /pseudo=""
     CDS             10089..10240
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="JQX68_RS19180"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19180"
                     /product="bacteriocin biosynthesis protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKLPVQQAYSVYGDKVLQKGHSLSTMPF"
     gene            10265..11611
                     /gene="albA"
                     /locus_tag="JQX68_RS19185"
                     /old_locus_tag="JQX68_19185"
     CDS             10265..11611
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="JQX68_RS19185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19185"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_071581776.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1078.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 2.1e-29,
                     bitscore: 99.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.3e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.5e-44, bitscore:
                     150.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.4e-06, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-21, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.2e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKEQMYPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRAKR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10280..10555
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JQX68_RS19185_Subtilosin_rSAM_RRE.1"
                     /evalue="1.40E-31"
                     /identifier="RREFam018.1"
                     /label="JQX68_RS19185"
                     /locus_tag="JQX68_RS19185"
                     /protein_end="97"
                     /protein_start="5"
                     /score="99.7"
                     /tool="antismash"
                     /translation="MYPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11624..11785
                     /gene="albB"
                     /locus_tag="JQX68_RS19190"
                     /old_locus_tag="JQX68_19190"
     CDS             11624..11785
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="JQX68_RS19190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19190"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11782..12501
                     /locus_tag="JQX68_RS19195"
                     /old_locus_tag="JQX68_19195"
     CDS             11782..12501
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="JQX68_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19195"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_040081524.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKIHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFAGLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYEKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12494..13804
                     /locus_tag="JQX68_RS19200"
                     /old_locus_tag="JQX68_19200"
     CDS             12494..13804
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="JQX68_RS19200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19200"
                     /product="bacteriocin biosynthesis protein AlbD"
                     /protein_id="WP_147772662.1"
                     /transl_table=11
                     /translation="MNSIISIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GINESVLGKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWVAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNYFAKKKN
                     WMFLLHAAIFACVCLSVAFMPAATIPLCAVHILWAVVIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIS
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYAGLLAGGFLLVAIIVGFISGRPIS
                     ALTFAQCMELLLAGAFIRLTADEKRPFFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVVPIAGLIIVYYLQKQDGGFFDTSKRERLGS"
     gene            13794..14954
                     /gene="albE"
                     /locus_tag="JQX68_RS19205"
                     /old_locus_tag="JQX68_19205"
     CDS             13794..14954
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="JQX68_RS19205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19205"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_147772808.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.1e-05,
                     bitscore: 23.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EPIIDAFGYAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKTFADMSFPS
                     SLSPEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFLDAADFIVDLMSQQKQLNILGQVQARDAQGHAPQTSAVTSGRIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKDIPPRVLEAVSAFQTNERELEQAKQFLRNEMLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14959..16239
                     /locus_tag="JQX68_RS19210"
                     /old_locus_tag="JQX68_19210"
     CDS             14959..16239
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="JQX68_RS19210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19210"
                     /product="pitrilysin family protein"
                     /protein_id="WP_147772663.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 1.4e-13, bitscore:
                     49.0, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIKYTESGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCLQAESGDTLLPYGIAHFLEHLLFWHNGRNLYNDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PASPAAVFPAGRIEDINALNIGDLQKAYKAAYKAHRMTLFLIGGSEDTEMLLPPHLQLQ
                     KRPHDQAKKKIIPACPPPLSQKMVLGDEERMEDTWTGLQIGALPGQNDLLTVKLYWDIA
                     SRILFQLDSPFFQEIQQTYRLEIDRLSAETHIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQQKEQVASWLQYGKNSLTDAIIYDSDYVRKCFEWAAECDRNDCSFLDMYHIIQDMDTQ
                     IFMSLIDALASSNKAIIHVSQKEAIKQ"
     gene            16236..16937
                     /locus_tag="JQX68_RS19215"
                     /old_locus_tag="JQX68_19215"
     CDS             16236..16937
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015250988.1"
                     /locus_tag="JQX68_RS19215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19215"
                     /product="bacteriocin biosynthesis protein AlbG"
                     /protein_id="WP_147772664.1"
                     /transl_table=11
                     /translation="MRKSTVFTLLLLLVGMAAYSFGWVQAAAESAAQYVQMINSDAVRL
                     GLLACTAAVLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNIRQTYVMAAVLCQVVIFGCMFEIVKAVPFRLYTPPAVSMGLALLLILYLLF
                     CMRTYLLQLLQHGSLFRKVLAGALAAAGIWWMLSFTISELLFLIIVAAIQQIGSSIYKH
                     ISDRRPASFEL"
     gene            complement(16943..18319)
                     /locus_tag="JQX68_RS19220"
                     /old_locus_tag="JQX68_19220"
     CDS             complement(16943..18319)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="JQX68_RS19220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19220"
                     /product="YncE family protein"
                     /protein_id="WP_147772665.1"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEIGREVPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTDNLSCTSEPCLIKTGPETEDIGVRYAVRVQGTVTLLVSVSPVRNQYGQGNGA
                     VSVIHSEEIDQVVYYAAQAGRCPDFSQITVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQ
                     SFVFTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFNKAFTYVLHGNTNLVSVID
                     NKTLSIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYMINIASQSVIDVIPIPGALDFA
                     LDPDGQYVYTANASSWSVDKYDVSTGQLAESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGSDFNRLFETLRTIVFSLDSTRAYFLEPYSEPFLIKNLSVVNTAR
                     QRIIANVSLPGAFDLTVTPDNQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     misc_feature    18286..18303
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18359..19714)
                     /locus_tag="JQX68_RS19225"
                     /old_locus_tag="JQX68_19225"
     CDS             complement(18359..19714)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="JQX68_RS19225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19225"
                     /product="YncE family protein"
                     /protein_id="WP_147772666.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDQPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHSVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTFTVTATILLDQPPRLIRFIPNHEFAYVFTGTAVYVIGIDTLTVDRSIPVEG
                     YDVAIDPNGLFAYVLNFGLVQKVDLFTGEVIGTIERDLIVSSIETDSLERYAYVLEQEF
                     LFNYLTVIDLNTFTISITQELEPDGQYAMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     IPQSARDFAFTPNGEFLYATHFLEQNITVYNTDDYSVETIISLGVSPGAIAI"
     gene            complement(19711..19941)
                     /locus_tag="JQX68_RS21905"
     CDS             complement(19711..19941)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="JQX68_RS21905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_125121078.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSV
                     YPQQFVQANTLIFHILLYLREQCMSEKEVKE"
     misc_feature    19895..19911
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19944..21089
                     /locus_tag="JQX68_RS19230"
                     /old_locus_tag="JQX68_19230"
     CDS             19944..21089
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="JQX68_RS19230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19230"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_017696253.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     gene            21073..21192
                     /locus_tag="JQX68_RS19235"
                     /old_locus_tag="JQX68_19235"
     CDS             21073..21192
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="JQX68_RS19235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JQX68_19235"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_014665774.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
ORIGIN
        1 ccgcctttat atttgtcctg gtcctcccat tgcttcgggt agccgatgcc cggctttgtt
       61 tctacattat tgaagtacat atattccgca ccggtacggt ttgtccatgt gtttttacag
      121 gtgacgctgc acgtgtggca gccgatgcat ttatccaagt tcatgaccat accgatttgc
      181 gctttaatct tcaagccaat cgacctcctt cagcttgcgg atgacgacat tcaggtcgcg
      241 ctgattcccc gttggaccgt aatagttaaa gccgtagctg agctgggcgt agcccccgat
      301 catctgtgtc ggcttgacgt gaatccttgt cgggctgtta tgggtgcctc cgcggttatt
      361 cgtcagcttt gttcctggca cgttgatgtg gcggtcctgg gcatggtgca taaacgccat
      421 tcctttagga atccgatgag acaaaaccgc tcttgcgacg actacgccat ttcggttgaa
      481 gcattcaatc caatcgttgt ctttaatatc cgtgtcctgt gcatcatctt tattcatcca
      541 tacggtcggc ccgccgcgga acagcgtcag catcggcaag gaatcaaaat acatgctgtg
      601 gacggaccat ttgttatgcg gcgtcaaata attgaggacg atctcttttc cctcttgatc
      661 aggccgcttg cttagaaacg ggcggtgctg gaggatcggt ttaaatgtcg ccatcgtttc
      721 accgaattcc atcatcagtt catgatcgac ataataggat tgtctgcctg tcagcgttcg
      781 ccacgggatt aatttctcca cattcgtcgt aaacggcgag tacctgcgtc cgcctttttc
      841 agagccggta aacgccggag aggtgatgac cgttttcggc tgggctgtaa tttgttcgaa
      901 cgtaaagcat tcttcctcac gctcttccgc caggtctttc agcttcaggt ttgtgatgtt
      961 ttcaagtgat tcccatgctt ttacggcgac cttcccattt gaagtggacg atagggttaa
     1021 aatcgcttct gccgcctgct ttgcttcact tatatttgga catccctttg ccacgctgtc
     1081 tgaggtgatt tctcccagtc tctttttgag tgattcatat tcatcggcta ttgaccagct
     1141 catccctttt gttccgctcg gctttaaagc agcgttagga ccgagtgcgg tcattttatg
     1201 aaaaatgtgt ttgtaatccc gttcaacgac ttggatgttc ggcatcgttt ttcccggaat
     1261 ggcttcacat tcgcccttgc tccagtcatt gattttgccg aatggctggg ccaattcctg
     1321 catggtgtcg tggaggagcg gcgtcgcaac cacttctttc accggctcca tatcgacttc
     1381 ttctgccaga tcggaaacgg cttttgacag cgccttgaaa atatcccagt ctgacttcga
     1441 ttcccacgga gccgagatcg ccggagcaaa tggatgaatg aacggatgca tatccgtgct
     1501 gctgaggtcg tgtttttcat accatgtcgc cgccggcaac acgatatcag aatacagcgc
     1561 cgtacccgcc attcgaaaat caagattgat taataagtcg agctttcctt ccggcgcctg
     1621 ctcccgccat ttgatttctt caggacggat gctgtcgctg tcgtcattca ttaaaccgtt
     1681 cgtcgtcccc agcaaatgct tgagaaaata ttcatgccct tttcctgagc ttgaaatcag
     1741 atttgcccgc catacaaaga gattccttgg gaaattcact tcattgtcag gatcttcaat
     1801 cgcgaatttc agttttttct cttggagctg tgaggctacg tacgcaccta cgtcttcaga
     1861 tgttgctgcc cctgcttttt cagcttcttt atacagatcg atgccatttt gattgaaagt
     1921 cgggtaagac ggaagccacc ctagccgcgc cgctagcaca ttgtaatcag cgtggtgctt
     1981 gtagcgggaa gacgcagcaa tcggtgatgc caaatcactg atcggctggt cctcataacg
     2041 ccactgatct gtcgcaaagt agaaaaatga agtgccgttt tgcagcttgg gcacgccctc
     2101 ccagtccttt gcagttgcaa tcgtctgcca cccttcagca ggtcggagct tttcctgccc
     2161 cacgtaatgg gcccagcctc cgccatttac gccttgggcg cctacaagca aaacaagatt
     2221 taacactgct cggtagatcg tgtcggagtt gaaccagtgg ttaatgccgg ctcctacgat
     2281 aatcatggac cggccgtctg tatcgatcgc attttgagca aactctctgg caatcttaac
     2341 gacagcttct tttttgattc ctgtcatttg ttcctgccag gcaggcgtaa acggctcagg
     2401 atcatcatag gagacagctt gttgttcgcc gatgccccga tttacgccgt agttagccag
     2461 tatcaagtca aacacggtcg tgacgtacgt ctcttcaccg ttcaggttca tttttttaat
     2521 aggaagatcc cgctcgagca ctttgtttcc gtcatttgaa aaatacggga tgcgcaccgt
     2581 gccgatttca tcctctattc cgagcacaga aagacggggt tcaatcgctt ctcctgtttc
     2641 ttcatcaatc atatgcaggt tccatttctg cttcccgtcc cagcgggaac ccattgtccc
     2701 ctgcggtatg gcaaatgccc ctgtctgttc gttccagacc gcgggcttcc actgatcatg
     2761 ctttgtctgc cgcccgatgt ccttcgcatg caaaaaccgg cccgctgtgt atacgccatt
     2821 ttcttttgat aaggtgacga gaaatggaaa atcagtgtat tgcttcgcat actcaataaa
     2881 acgttcagtt tcttggttca cgtagaattc ctgaagaatg acgtgaccca tggccatcgc
     2941 aagcgccccg tcagtccctt ggcggatact cagccagtca tccgcgaact ttgaggattc
     3001 cgcaaaatcc ggactgatcg aaatgacctt agcgccttta tagcgggcct ccgccaaaaa
     3061 gtgcgcgtca ggggttctcg ttaacggaac gttggagccc catgtgatga tatagcctga
     3121 attgtaccaa tcactgcttt ctggaacgtc cgtctggtca ccccaaattt gcggggatgc
     3181 tggcggaaga tccgcatacc agtcataaaa actgagcatt gggccgccga ttaacgacat
     3241 aaaccgggag cctgaggcgt ggctgatcat ggacatggcc ggaatcggag aaaagccgac
     3301 attccggtct ggcccgtatt tcatcactgt atacagcaga gaggctgaaa tcagcttcag
     3361 cacctccggc cattcagcac gaacaaaacc gcctttccct ctcgcctgtt tataggactt
     3421 cgctttttca gggttttcaa cgattgattt ccaggcatcc agcggatttt gatgcatctg
     3481 caatgcttcc cgccacaaat tgatcagcac accgcgcacg tatggatatt tcacacggag
     3541 cgggctgtag atataccatg aaaaactggc cccccgcgga cagcctctcg gttcgaaatc
     3601 aggcatatcc gggcctgttg atggataatt caaattttgt ccttcccacg tgacaattcc
     3661 gtttttcaca taaatattcc agctgcaaga ccccgtgcag ttaacgccgt gggtggagcg
     3721 aacgactttg tcgtactgcc atctgtttct gtatacattc tcccaatcgc gatcttcgcg
     3781 ggtggtttgg ctatgtttat ttgaatggtg ttctatagga gagaaaaaat tcaatctcct
     3841 aaacaacgga ctcattttct ttttcttcat gagagttcac tccttccgag tcaggtggtg
     3901 ctaagttcac tataaacaga gacagcgtgt tcccttgtga actatgtcac acactctgct
     3961 tttttcacaa aatgttcaca caaaggagaa ggaaggattt tcacaggatg tgaggaaggc
     4021 cgcgtttgca ggacgcctga tcatgagccg ccttttcatt caaagatcaa aaaacccggc
     4081 tctatttaag aaccgggctc agcattttcg tcttgtgatg tatgcaaata ccgcaaaaat
     4141 aactgatagg aacaaaaaac attttgctga agcatggcca aaaagttcat ttgcagctgc
     4201 ggattgtaag acatcatttt tttaaatacg taataaggga tattgagaat cagaatgtct
     4261 gaagtggcat tgactgtgat aaaaggcgat aaataaagcc cgcctttttc atcaatcgga
     4321 aacacatcgc ctttttccca cagcgcaacg gttttcgacc cttcagggag cctggtgtcc
     4381 ataaaacgga cactgccttt taatacaata taaacagatt gtgaatgaag aaaggatgga
     4441 gtttgatcac atgagccgct gataaacgtg ccgtttttca gcaaggtttc gacaatggat
     4501 agaggcactt cattaaacat gggaagttgt ttcagaaata ataaatagtc acactgattc
     4561 ataagaaagc ctcctgtgct aaggatagct ttagtgtagc tcgactgagc ctgtacagca
     4621 gtgatgtatt tcacagcctg tatgatgaat gtcacttatc aggagggtga ctgcatttat
     4681 aatgaaagaa aaaaggaggg tttcgatgaa agcgctgatt ccgaagcagc acggcgcatg
     4741 ggcgatgctg ctgatcccat ttttactagg catagtcaag ggaggccccg ttatctggca
     4801 tatcccgctc ttccttggct ggcttttcct atacttagcg gtttatcccg ttacacttgc
     4861 cttgaaaaag aaacaaatca aaccatatca aaagtggatg tgttattacg gttttcccgc
     4921 ctgctgcttt ttgatgatcc ctctctttca taagccgcct ctcatctggg tgggcgtttc
     4981 tttactgccg ctgtttctca tccatatgta ttttgcccgc cgaaaaaatg aacgagccct
     5041 attgaatgat gttgcaggtg ttttgttctt ttgttcgggc ggtcttgcaa gctgctggct
     5101 ggggatggga acccttgacg gctgggcttg gtttattttc ttgcagtctg ctttattttt
     5161 tatcgggagt tccttttatg tgaaatcggt gatccgtgag agaaaaaaca gggcatttgc
     5221 atactggtca tggggatatc acctgctgct ccccttttta tccgctcttt tcggagctgg
     5281 atgggcgttt ctcgctttta tcccaagcag cttgcgggca tggttttttc atggcaggga
     5341 ttggcctgtg aaaacgattg gcattctgga aatcgtgaac gcctgcttct tttttgccgt
     5401 catgtgcctc tttatgacaa ggtaaaaaaa caaggacacc gctgtccttg tttttttcag
     5461 tcaatattgc aaatctccag cggacaattt tcacactcaa tttcacatcg caaatagtcc
     5521 cgcttgtgca aaataatttt tccagattcg tctatcgaaa taaccccttg tttgcggaga
     5581 tctccgagca tgcggttgac gctttccctt gcagccgcgc aaaactttgc caaatcctga
     5641 tttgtcagga caatgttaat cagaatgccg tcgcttcgct ccactccgta gctgtttgat
     5701 aagcggataa gggtggaata gagcgcaccc tttttgccgt gaagaagcag atccctgatt
     5761 ttggactgaa ttttccggag atgggtgctc atccatttca tgaactcaaa tgtcaaagcg
     5821 ccgttttgga ttaattcttt ttccagctta tttttattaa tgacgagcac ctcgccatcc
     5881 tctagcactt ttgcactaag catatacctc ggttcttcag tgaaaagtgt taattcaccg
     5941 acgatatcgt ttttttggca gattctaagc gtcaggtctt ttccgtcaga tgtcagcttg
     6001 ccgatttcaa tgagtcctga ttgaatcaga taaagctctt ctgcatccat tccttctcga
     6061 aacaaatacg tgtgtttttc catttttctt ttcgtgctga tcgattccag caattcatgc
     6121 agatcactgg atataagatc actatcagat ggtcgaacag agagaaaatt catgagctca
     6181 cctcgaagaa agtcacgttg tgtgtttatt gtaacgtgaa ttgatttgta cccatcgaga
     6241 aaaaactaac aatcttgtga atgctccagt gttagttgat gctctgactg tttctctccg
     6301 tgtgcatttt cattctttcc tgccaataca tccagatcac aaggacaaag ctggctaacg
     6361 ccacctctga aagcgccata aatccgatcg catattggcc tgttgcctga aacacactcg
     6421 ccaatatcag cggaggaaaa aaaccgccta atccgcccat ggcagacaca ataccatttg
     6481 caatccccgc ttgcttcgaa aaatagaaag gcaccagttt aaaaaccgtc ccgtttccta
     6541 tacctgagca gaccgccaca gttaatgacc caaacgtata aaggccgatt gtcggcgaga
     6601 acgataagat aatgcctgat aatgtaagcc ccgcaaaaac gaacatcaag atgcggagag
     6661 ggcttatttt atcagccagg aatccgcccg caggcctgag cagcgtagag accgcaataa
     6721 agccagccgt ccgcaaaccg gcatccgccg gactcagtcc aaagtgctcc accagaaagt
     6781 tcggcaaata gatggtgaag gcgacaaagg caccaaacgt aataaaataa aacaggctca
     6841 gaaaccacag gacatgattt cggtaaacgg ctttgatttg ggtctttaca gaaactttga
     6901 ccttcttctc atgcctgtcg ccgaataaaa catgcagtaa ggcaaagaca gccagcaaaa
     6961 ccagatacat ctgtacggtt gctttccaac cgacggcttg agcgataacc ggcgccgcaa
     7021 atgtcgtaac ggctgtcccg atatttcctg caccgtaaat cccattgacg acaccgtgct
     7081 tttccttcgg ataatatttc ggaagggagg tcaccccaat ggagaatacc gctcccccga
     7141 tccctaagaa aaagccgccg gcgattaaat caaacaaaga attcgcaata ctgatccaaa
     7201 atacaggaaa caaaagcaag ataaagctga tcataaacat cagccgcgcg ccaaacctgt
     7261 tcgttaaata ccctaaagga atgcggagta gcgacccgag gatcacagga atcgccgtca
     7321 ccaaagaaat ctcgcccttg cttaaatgaa tatctaatgt gatttgggaa atgagtgatg
     7381 aaatcagcac ccaaaccata aaccctgcca ccaagcttaa tgactgtaac gataattgaa
     7441 tgtgttgacg gttgatcatt tggcttgccc ctttcaatga ttcaataatc agtcttatca
     7501 tacaaaaact cggcaaacag gattgtgaaa tacatcacac gttttcctca taaaaaaagg
     7561 acaaagcccg aagactttgt ccttacatca tcattacatt ttttccggag ccgatacgcc
     7621 aatcagctga agcgcgttgt tcagcgtaat ttgcgttgcc ttcattaaag ccaggcgcgc
     7681 gcggcttttc tcttcatttt caggatcgat gactttctct gcgttgtaga agctgtgcag
     7741 agcggaagcc aggtcataaa tatagtttgt gacacggtgc ggaattcgtt tttccgctgc
     7801 ttccgccact gcctctggga agccgccgat cgttttcagc agatcatatt ctttttctga
     7861 ttggatatgg ctgaaatcaa ggtctgccgc aggtgtaagt ccctgctcct ccccttggcg
     7921 aagcatgctg caaatacggg catgcgcata ttgtgcataa tacactgggt tttcgttaga
     7981 tgttgataca gcaagatcta agtcaaaatc catatgtgtg tccgcactgc gcatcgcaaa
     8041 gaagtaacgc acggcatcca agcctacttc ttcaatcaaa tcacgcatcg ttacggcttt
     8101 accggtccgt ttgctcattt tcattttctc gccgtttttg taaaggtgaa cgagctgaat
     8161 gatttctact tcaagcgttc ctttttcata gcccagcgct tcgattgccg ctttcatgcg
     8221 cgggatgtag ccgtggtgat cggcgcccca aacgttgatc agcttatcaa agccgcggtc
     8281 aagcttgtcc ttatggtacg cgatatcagg aagcaggtac gtgtacgtgc cgtccttctt
     8341 gatcaatacg cggtctttat catcgccaaa cgtcgtagag cggaaccaag tcgcgccgtc
     8401 ttcttcatag acatggcctt tttcgcggat cgcttcaagc gccttatcga tttttccgtt
     8461 ttggtacaga gacgtttcgg aataccacac atcaaacggc acacggaagt tttccaagtc
     8521 cttgcgcagc ttatccagct cgtatttcag gccgtattca cggaaaaacg cgaggcgttc
     8581 actttcctct tcattaacaa aacgatcgcc gtattcctca gcgagacgct ttccgatcgc
     8641 aataatatcc tcgccgcggt agccgtcctc cggcatcggt ttctccaagc cgagcgcttc
     8701 aaagtaacgg acttcaacag aaagcgccag attgttgatt tggtttcccg catcgttaat
     8761 gtagtattcg cggcttacat cataacccgc ttttgaaagc acgttgcata aggagtcacc
     8821 gacagccgca ccgcgtgcat gtccgaggtg aaggtctccc gtcggattcg ctgatacgaa
     8881 ttcgacctga actcgttcac cgtttccgat gttcgtttcc ccgtatgctt cccctgcttc
     8941 cagtacagac ggaatcagct ttgttaaata ttgattgttc atatagaaat tgataaaacc
     9001 cgggccggcg atatccagtt tttcaatcga agcctttcct ttatcaaaat gagcgacaat
     9061 ctcttcagcg atttggcgcg gcgctttttt tgcgactctc gccagctgca tcgccatatt
     9121 tgtagagtaa tcgccgtgtg ttttatcttt cggtgtttct aaaacgacat taggaagctg
     9181 gctttcttca gccagtcccg ctttcagaac ggccgctttg atttcttctt tcagcacgtc
     9241 cttcatttgt tccgcaatgt tcatgcgtga gttcctccct catacgtgat cgtcatatta
     9301 tgtaaatgct cctgctcgtc tccgacatgc atgtcatatg cgatgctgat acggccattt
     9361 tcttcaccga gatcagattg aatcgatttt gtgcttgttt tcagctcaag ctcaccaaat
     9421 gacattttat atttagcaat tgtggaagct cccgttacga aacgctgatt cattttgaca
     9481 gcgcctgacc tcatgaccag gacttcgcct tcgcttactt tcacaatcgt tttgactttg
     9541 cctaagtcgt gttcttcata ataagataga tacactttat tttgttttac atagtaaaat
     9601 ccggtggtgc ggaattcgat gacctcttgg tttccgtcat cctcaatcac agacttcaca
     9661 tggagtgtta tcggtgtctc ttgcttcatt ctgacacgtc cttttcatca ttccactttg
     9721 acttgaatag tataatcatt cggtttgtaa acttcaactg cttctatctt accatcattg
     9781 ctcatcagat ttgaagataa acctcataaa aagcatttcc ttaatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccatttcaca
     9901 tttttttcaa aatatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtttagtgg acggcccaat
    10081 ccctgatttt gaaattgccg gtgcaacagg cctattcggt ctatggggat aaggttctcc
    10141 aaaaagggca tagtctttct actatgccct tttaagtaaa ttacaatttt taactaaaat
    10201 ctacctcttg tatatacata cacaatcgtt tttcatttga atcatagata taggggatgg
    10261 tattttgttt aaagagcaga tgtatccatt tattaatgaa agtgtaagag ttcaccagct
    10321 tcctgagggt ggcgtgttag aaatcgacta cttgcgcgat aatgtctcca tttctgactt
    10381 tgagtacttg gacctcaaca aaacggctta cgagctttgc atgcgcatgg atggccaaaa
    10441 aacagctgaa cagattttag ctgagcaatg tgccgtgtat gacgaatctc ccgaagacca
    10501 taaagactgg tattacgaca tgctcaacat gctccaaaac aagcaggtca tccagcttgg
    10561 caaccgggcc aaacgccata caatcaccac gagtggaagc aatgaatttc caatgccgct
    10621 ccacgccaca tttgagctga cgcaccgctg taatttgaaa tgcgcccact gttatttgga
    10681 aagctcgcct gaagcgctcg gcaccgtgtc gattgagcaa ttcaaaaaaa cggctgatat
    10741 gctgtttgat aacggtgtat tgacatgcga aatcacgggc ggggaaattt ttgtccatcc
    10801 aaacgccaat gagattcttg actatgtgtg taaaaagttc aaaaaagtcg ctgtcttaac
    10861 gaacggaaca ctcatgcgaa aagagagcct ggagcttttg aaaacgtaca agcaaaaaat
    10921 catcgtcggc atttctcttg atagtgtcaa ttccgaggtt catgactcct ttagagggag
    10981 aaaaggctct tttgcccaaa cttgtaaaac gataaaattg ttgagtgacc acggtatatt
    11041 tgtcagagtc gccatgtccg tcttcgaaaa aaacatgtgg gaaatccacg atatggccca
    11101 aaaggttcgg gatcttggag cgaaggcgtt ctcttacaat tgggttgatg atttcggaag
    11161 aggcagggat attgtccatc caacgaaaga cgccgagcag caccgcaagt ttatggaata
    11221 cgagcaaaat gtgattgatg agtttaaaga tttaattccg attattccct atgagagaaa
    11281 acgcgcggca aattgcggcg ctggctggaa gtccattgtg atcagcccgt tcggcgaagt
    11341 acgtccgtgc gccctctttc caaaggaatt ttcattggga aatatttttc atgattccta
    11401 tgaaagcatc tttaactccc ctctcgtcca taaactgtgg caagcgcagg cgccgcggtt
    11461 cagcgagcat tgcatgaaag acaaatgccc gttcagcggc tattgcggag gctgttactt
    11521 aaaagggctg aactctaaca aatatcaccg gaaaaacatt tgctcttggg cgaaaaacga
    11581 acaattagaa gacgtggtcc agcttattta ggagggaaac gatttgtcac cagcacaaag
    11641 aagaatttta ctgtatatcc tttcatttat ctttgtcatc ggcgcagtcg tctattttgt
    11701 caaaagcgat tatctgttta cgctgatttt cattgccatt gccattctat tcgggatgcg
    11761 cgcgcggaag gctgactcgc gatgagcatt ttggatatac acgatgtatc cgtttggtat
    11821 gaacgggaca acgtcatctt agaacaagtg gatttacatt tagaaaaagg cgccgtttac
    11881 ggcctgcttg gggtaaacgg cgccggaaaa acgacactga ttaatacgct gacaggcgtg
    11941 aatcgcaatt tcagcgggcg ctttacgctg tgcggaattg aagcggaggc cggcatgccc
    12001 cagaaaacat cagatcagct gaagattcac cgttacttcg ccgccgatta tccgctgctg
    12061 tttacagaaa ttacggcgaa ggactatgtg tctttcgtcc attcgcttta ccaaaaggat
    12121 ttttcagagc agcagtttgc cggtttagcc gaggcctttc atttttcaaa atacatcaac
    12181 aggagaattt cagagctgtc cttggggaac aggcaaaagg ttgtgttgat gacaggctta
    12241 ttgctgcgcg cccccctgtt tattttggat gagccgctcg tcggtttgga tgtggaatcg
    12301 atagaggtct tttatgagaa aatgcgcgag tactgtgagg caggcggaac cattttgttc
    12361 tcttctcatc tgctcgatgt cgtgcaaaga ttttgtgatt atgcggccat tcttcacaac
    12421 aaacagatcc aaaaggtcat tccgattgga gaggagaccg atctgcggcg ggaatttttt
    12481 gaggtgatcg gccatgaata gcataatctc catcatgtct ttgctgttca agcagcttta
    12541 cagccggcaa gggaaaaagg atgccatccg cattgccgca ggccttgtca ttctggccgt
    12601 ctttgaaatc gggctgatcc gacaggctgg cattaacgaa tcggtgttag ggaaaacgta
    12661 tatcatactc gcacttctct tgatgaatgc gtatatggtg tttctttctg tgacatctca
    12721 atggaaggaa tcttatatga agctgagctg cctgctgccg atttcttcac ggagcttttg
    12781 ggttgcccag agtgtcgttc tgtttgtcga cacttgtttg agaagaacat tattcttttt
    12841 cattttaccg ctgttcttat ttggaaacgg aacgctgtca ggggcgcaaa cattgttttg
    12901 gctcggcaga ttttcgtttt ttaccgttta ctctattatt ttcggagttg tgctaagcaa
    12961 ctatttcgcc aaaaagaaga actggatgtt tctgctgcat gcggcgatat tcgcctgtgt
    13021 atgcctcagc gtcgctttta tgccggccgc cacgatcccg ctttgcgcgg ttcatatcct
    13081 gtgggcggtg gtcattgact ttcctgtctt tctgcaggcg cctccgcagc agagcaagat
    13141 gcattcattt atgcggcgat ctgaattttc gttttacaaa agagaatgga accgatttat
    13201 ctcttctaaa gcgatgctgt taaattacgc ggtgatggcg gcgttcagcg gattcttttc
    13261 gttccagatg atgaacaccg gcatcttcaa tcagcaagtg atttatatcg tgatttccgc
    13321 gcttttgctc atcagctcac cgatcgccct tttgtattcg atcgaaaaaa acgaccggat
    13381 gctgcttatc acgcttccga tcaagcggaa aacaatgttt tgggcgaaat atcgctttta
    13441 tgccggtcta ttagcaggcg gatttctcct tgtcgcgatc attgtgggtt tcatcagcgg
    13501 ccgtccgatt tcagctctta cttttgcgca gtgtatggaa ttgctgctgg cgggagcatt
    13561 tatcaggtta accgcggatg aaaaacggcc cttcttcagc tggcagacgg agcagcagct
    13621 atggagcggt ttctcaaaat atcggtctta tctgttttgt cttcccctat tcttagccac
    13681 attagccggc accgctgtct ccctggcggt cgttccgata gccggtctga tcatagtcta
    13741 ttacctgcaa aaacaggatg gtggtttctt tgatacaagc aaaagagaac ggcttggaag
    13801 ttaacctgct gaagactcat caattttcaa ctatttcaat cgccgcgagc tttctgaaac
    13861 cgatcgaaag cgcggcggaa cctgaggaag aaacaattta tttttacggc gccgccgcat
    13921 acctgaagga gccaatcatt gacgctttcg gttatgctgc cggcagccgt ttcatgtact
    13981 cggcgaatct cttttttgat cagcagctga aaacctgcgg gacccgtttg attcacccat
    14041 tgtataacgg gaatcttcat gttgacgccc taatgaaaac ttttgcagac atgtctttcc
    14101 cttcttccct ttcacccgaa gccgttgaaa aagcacggaa tgagctgctg ctgaaaatcg
    14161 aaaagaaatt cactgatccc ttctcctact cggcagcgcg cttggctgag gaggtcttcg
    14221 gaaacccgat gtacggcaca ggcatgtttg gccggaaaga caggataaag gcgattcatc
    14281 ctaaacggtt tcttgacgca gcggacttta tcgttgattt aatgtcccag caaaaacagc
    14341 tgaacatatt gggacaagtt caagcacgtg atgctcaggg acatgccccg caaacgtccg
    14401 ctgtaacgtc cggaagaata cccgtgaacc ggcatgtttt tgaaacagag acacgcagcg
    14461 ctgcaggtcc ctccgtctta acactcggat ttgattgcgg agagatgaaa gatgccagcg
    14521 attatatcaa aatccagcta atagacggat tactgggaaa gtacggccat tccgctttat
    14581 tcaagcactt ccgagagaag gatctggcag tctatcacgt catcacccgt tacgatgtca
    14641 tgaacaattt gctgcttgtt tctatatgta cggatcagct tcatgaaaag gatatacctc
    14701 cgcgcgtttt ggaagctgtc tcagcttttc aaacgaatga gcgggaactg gaacaggcaa
    14761 agcaattttt acggaatgaa atgctgctgc aattcgattc tcccgaaggt ctgttggctt
    14821 atatggggat tcttcgccgc ttctcctgca cgaaagaagc cttgctggat ggcatctcag
    14881 cggtaacgtg ccgtgatgta ttgcaattca tagcgactat caattatatc ggagctcatg
    14941 tagtaagggg atgaagagat ggaaaagaaa gccttttttc aacagctgga tgaacgaacc
    15001 gatatcaaat acacagaaag cgggctgaaa atattcagat taaaattccc ccgcgcccat
    15061 ctgcgcctgt gcaatgtgaa aatcgatttc ggaagccgtg atgtctgctt acaggcagaa
    15121 tccggcgaca cgctgcttcc gtatggcata gcgcattttt tagagcatct tctcttctgg
    15181 cataacggcc gcaacctgta caatgatttt tttgcgcatg gcgcgctttt aaacgcattc
    15241 actacctaca ctgataccaa tttcatgttt acctcattac cggatcggct cagacaaacg
    15301 atccccatcc tgcttgatgc tttatggaac cactcatttg acaaaaagat tgtcgctcag
    15361 gaaaaagctg tgattacaag cgaaattcaa acagcacacc ttaaccatca gctctcatat
    15421 cattatcagc tgatcagcat gctttctccc gcctcacctg ctgccgtttt ccccgcaggc
    15481 agaatcgagg atattaacgc gctgaacatc ggtgatttac aaaaagccta caaagccgcc
    15541 tacaaagccc atcggatgac gctgtttttg attgggggtt cagaagatac ggaaatgctt
    15601 ttacctcctc accttcagct gcagaagcgt ccgcatgatc aagctaaaaa gaaaatcatc
    15661 ccggcgtgcc ctccacccct ttcacaaaaa atggtgctgg gtgatgagga gcggatggaa
    15721 gatacatgga ccggattaca gatcggcgca cttcccgggc aaaacgatct gttgaccgta
    15781 aagctttatt gggatatcgc gtctcgtatt ctatttcaat tagattcacc gttttttcaa
    15841 gaaattcagc aaacgtatcg cctggaaatc gatcgcttgt cagccgagac acatatatat
    15901 gaggatggcg gtttcttgat ccttcacagt caagggaccc attcttcagc ttatattgat
    15961 gtcgcatcat actatgtcac gcagcagaaa gaacaggttg cttcctggct tcaatacggc
    16021 aagaactctt tgactgacgc gatcatttat gacagcgatt atgtgcgtaa atgcttcgaa
    16081 tgggcggccg agtgtgacag gaacgattgc tcgtttcttg acatgtacca catcattcaa
    16141 gatatggata cgcagatttt catgtctctc attgatgcat tggcatcttc taacaaagcg
    16201 atcattcatg tttcccagaa agaggcgatc aaacaatgag aaaaagcact gtctttacct
    16261 tgttattgct gcttgtcggt atggcggctt attccttcgg ctgggttcag gccgccgccg
    16321 aatccgccgc ccaatatgta cagatgatca acagtgatgc cgtgcggctc ggactgctgg
    16381 cttgtaccgc cgccgtcctg atgctgcctg cttttctcta tcttcactat gtcacccaat
    16441 ccgtgaaaaa catgacagca gcttttcaga aactcacaca gtctcatcaa agctgctgtg
    16501 actttcagca acacaacctg tgcagccgct atgcagaaga cgtcaaatcg ctgcgtgaca
    16561 gctataaaaa catccgccaa acatacgtga tggctgctgt attatgccaa gtcgtcatat
    16621 tcggatgcat gttcgaaatc gtcaaagccg tccctttccg cctttacacg ccccctgccg
    16681 tttcaatggg gcttgcgctg ttactgatct tgtatttatt gttttgcatg cgaacgtatt
    16741 tgctgcagct tttgcagcac ggcagcctgt tcagaaaagt gcttgcggga gcgcttgcag
    16801 cagccgggat atggtggatg ctcagtttca ctataagtga actgctgttt ctgatcatcg
    16861 tagcggcgat ccagcagatc ggatcatcaa tatataagca catctctgat cgccgccccg
    16921 cttctttcga actataaagc ttctacattg caatcgcaga cggacccgcg ccaaccggaa
    16981 tcaccgtcac agctgtataa tcgctcgtgc ggtacacggt cacagcattg tcgttgggct
    17041 gtgccgcata aatatactga ttgtccggcg ttacggtgag gtcaaaggcg ccgggcagag
    17101 acacgtttgc aatgatcctc tgtctagccg tattaactac ggataagttt tttatgagaa
    17161 acggttcact ataaggctct agaaaataag ctctagtgct gtccaaagaa aatacaatcg
    17221 ttctcagagt ttcaaataaa cggttaaagt cgcttcccct gcttaatggt gacagactga
    17281 tctccgttac acctttcggc cacagctcac cattcaacac gtacgcaaaa tttccagcgt
    17341 aaggagttgc aattaaactg gggaattcaa atgaatcgat gatactttct gccaactgac
    17401 ctgtacttac atcatattta tcaaccgacc aactgcttgc attagcggta tagacatact
    17461 gtccatccgg atcaagagca aagtctaaag cgccgggtat cggaatgaca tcaatgaccg
    17521 attgagaggc tatgttaatc atatatatag atccggcggc catcacgtac gcgaactcat
    17581 ctgttggatc aaattcgatc tttctcggcc ctcctccaac agtaatggta tttatgatac
    17641 tcaatgtttt attatcaatc actgagacaa ggttggtatt cccatggagg acatacgtga
    17701 atgctttatt gaaagtaacg cctagattag ttggcacgtc agaaaaaggg attgttttta
    17761 caaccgtgtt taaatctgca tcaataaccg aaaccgtgct gtctccagta ttagcagtaa
    17821 acacaaatga ttgagggtct ggtgatggcg gtaaaacaag tgtaccggtc actgtaagcg
    17881 gactgccgta gaaaggcggt acaatgagaa ggtcttccac tgttatttga ctgaaatcag
    17941 gacagcggcc agcctgcgct gcataataaa caacttgatc aatctcttca gaatgaatca
    18001 cagaaaccgc cccattgcct tgtccatatt gatttcgcac aggcgacaca ctgacaagaa
    18061 gagtaacggt cccttgtact ctcacagcat atcgaacacc gatatcttct gtttcaggcc
    18121 cagtcttgat taagcaaggc tcactggtgc aggacaaatt gtctgtactc catgtaacag
    18181 ccgctgacgc ttcagccgaa tcaaccttaa agccctcagg gatatctata ggcacttgaa
    18241 acggcacttc ccggccgatt tcctcatcac aaaaacagaa acaattttcc tgtaaagcag
    18301 aaagatcatt ctttttcatg atttcacgtc cttttagaaa tgcacagcat tcagttgatt
    18361 agatcgcaat agctcccggt gaaaccccaa gagatatgat agtttccaca gaataatcat
    18421 ccgtgttgta aacagtgatg ttctgctcta aaaaatgggt tgcatacaga aattcgccat
    18481 tcggagtaaa cgcaaagtct cttgccgatt gcggaatatt tcctataacg cctgctccat
    18541 tcggactgac agaatacaaa ttgccagtga agctgtcatg taaatacacc tctgatccac
    18601 tcgtaaacat tgcatattgg ccgtcaggct ccagttcttg ggtaatgctg atcgtaaacg
    18661 tatttagatc aataaccgtc aaataattga ataagaattc ttgttctaac acatacgcat
    18721 acctctccag agaatctgtt tctatggatg atacgataag atctcgttca atcgttccta
    18781 tgacttcacc agtgaatagg tccacttttt gcactaaacc aaaattaaga acataggcga
    18841 ataacccatt ggggtcgatt gcaacatcat atccttctac aggaatcgac ctatccacag
    18901 ttaacgtatc aattccaatc acataaaccg cagtaccggt gaaaacataa gcaaactcat
    18961 gattagggat aaatctaatc aatcgaggcg gctgatccag caatatagtt gctgtcactg
    19021 taaatgtgtc ataatcgatg acagaaatca cattattgtt gggatgtaag acaaacacag
    19081 cgcttttatc tggcgtaatt tcaatacctg ccggattgta cggaagagca atcgttgtca
    19141 caacagaatg agtgtttgta tcaatcacag aaactgattg atcatttgga ttcgctgtaa
    19201 acgcataaac gggttccggc tccggtacaa gcacaatcgt ccccgtcacc gataaaggac
    19261 tgccgtaaaa gggcggaaca acaacaaggt tctcaatcgt gatgtcactg atatccgggc
    19321 aatcatccgg ttgatcggaa taatagacga cttgatcgat ttctgcattg tgaatgacgg
    19381 aaacagcccc gtccccttgt ccatattgat ttcgcacagg tgagacactg acgagcagcg
    19441 taacggttcc ctgcaggcgc actgcaaatt gaacaccgac ctcatcaggc tctggccccg
    19501 tttgaattaa gcaacggtca ctgacacaag aaaggctgtc tgcattccac gtcacgtttg
    19561 caacagcttc agccggatca acgacaaacc cttcaggtaa ttcaatcggt gcttgaaaca
    19621 tggcttctcg gcttgcttct ccctcacaaa aacataagca ctcttcttgt tctgctcctg
    19681 ctttttcttt aaaggaaagc ttgttttttc tcattccttc acttcctttt cagacataca
    19741 ctgctcacgc agatataaca gaatatggaa gattaacgtg tttgcttgta caaattgctg
    19801 agggtaaacg cttctttttg aaaatatatc tccaaacatg cggtgtaacg aaagaaaaaa
    19861 ttgcggtttt tttgcgcttc tcacaagaat gttgatgata aaatatgaca tatatagaat
    19921 tatgaaggga gggatttgca aacgtgacag gtgtcatatc ttcttcttcc atcggagaaa
    19981 agattaacga atggtatatg tacatacgcc gatttagcat acccgatgca gaatatttgc
    20041 gacgagaaat caagcaagag ctggatcaaa tggaagaaga tcaagacctt catttgtact
    20101 attcactgat ggagtttcgg cacaacctaa tgcttgagta ccttgaaccg ttagaaaaaa
    20161 tgagaattga ggaacagccg agactgtctg atctgctgct tgagattgat aaaaaacagg
    20221 ctcgtttaac tggtctgctt gagtactatt ttaatttctt cagaggcatg tatgagctgg
    20281 atcgccgtga atatgtatta gccattcaat tctttaaaaa agctgagagc aagctggttt
    20341 ttgtgaaaga taaaatcgat aaagctgaat tctttttcaa aatgtcagaa gtctattatt
    20401 atatgaaaca aacttatgtc tccatggact atgcacgtca agcatttgaa atatacagtg
    20461 aacagactac atatgatatc agaatgattc aatgccagtc cttattcgga gccaactttt
    20521 tggatttaaa acaatacgaa aaagcaattg cccattttca aaaagccttt acacttgcaa
    20581 aaacagagca gcagccccaa ttaatgggaa gaacacttta taacatagca ctctgcaagc
    20641 aaaaccaaaa cagttttgaa tcagcgatag agtatgtaaa aaaatctatt caagtatttg
    20701 aaggatctaa aatgctccct tcactgccac aagctttttt cctaattaca caaatttatt
    20761 ttaaattagg taagattgat aacgcctgtg aatatcataa aaaaggaaaa gagtattctg
    20821 cagctgcggg agataccgtg tatctaacgg agtttgaatt tttggaatct ttatacttgt
    20881 ctggaccgga tgaggaacgg atagaaaaat gttttgtttt tcttgaaagt aaaatgatgt
    20941 atgcagatat tgaggacttc gcacttgatg ttgctaaata ttatcatcaa caggaaaatt
    21001 acaaaaaagc atctcattac tttttaaagg ttgaagaagc aagacagcac attcaagggg
    21061 gggtgaattt atatgaaatg gaagtataaa ttattactcg cttgtttagc tgtgagtgct
    21121 gtatttatca cagtcgaagt atcaaattca tcaacagaac attttgatgt tgcgcaacgc
    21181 gccatgatct aaaccgccgt ccatcggcgg ttttttttgt cccctcttta cccaatctcc
    21241 caattcatac tatgattttt ttcaataatc ttgaagagag tggcaatgca gcatgtctct
    21301 gtaaagtgtg agagcccact ttacacagtg gaatcgagaa aatgatgtga cggagtttga
    21361 aacgtcgagc gcgacactgt tgaacaggca gctgagacga tcggcgtgag cccggctaga
    21421 atcgccaaga ccctgtcctt cagaggggaa ggagatcagg cgattctgat tgtggcagcc
    21481 ggcgatgcca agatcgacaa caaaacgttc aggcaaacat ttggctttaa agcaagaacg
    21541 ctctctccta atgaggtgct ggagcagaca ggccatgaaa ttggaggagt ttgcccattt
    21601 ggattggctc a
//
