LOCUS       NZ_CP070260            24382 bp    DNA     linear   CON 30-MAR-2024
DEFINITION  Streptomyces californicus strain FDAARGOS_1210 chromosome.
ACCESSION   NZ_CP070260
VERSION     NZ_CP070260.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces californicus
  ORGANISM  Streptomyces californicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7919564)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7919564)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2021) Institute for Genome Sciences, University of
            Maryland School of Medicine, BioPark II, 801 W. Baltimore St., Suite
            619, Baltimore, MD 21201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 8.0.0, HGAP v. 4
            Genome Coverage                   :: 624.55x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016906265.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 09:02:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,240
            CDSs (total)                      :: 7,147
            Genes (coding)                    :: 7,032
            CDSs (with protein)               :: 7,032
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 115
            CDSs (without protein)            :: 115
            Pseudo Genes (ambiguous residues) :: 0 of 115
            Pseudo Genes (frameshifted)       :: 36 of 115
            Pseudo Genes (incomplete)         :: 97 of 115
            Pseudo Genes (internal stop)      :: 12 of 115
            Pseudo Genes (multiple problems)  :: 27 of 115
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:25:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7880840
            Orig. end                         :: 7905222
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070260.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24382
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="33"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..24382
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24382
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14382](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14382)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            108..551
                     /locus_tag="I6J40_RS34140"
                     /old_locus_tag="I6J40_34130"
     CDS             108..551
                     /NRPS_PKS="Domain: Polyketide_cyc (10-112). E-value:
                     1.8e-14. Score: 46.1. Matches aSDomain:
                     nrpspksdomains_I6J40_RS34140_Polyketide_cyc.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970039.1"
                     /locus_tag="I6J40_RS34140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34130"
                     /product="SRPBCC family protein"
                     /protein_id="WP_030117041.1"
                     /transl_table=11
                     /translation="MSSSLVETIDVKAPVAITWALWSDVTQWPRFLSHVQRVDPIDERR
                     FAWQLSLPGADKNFVAELTEVVTENRIAWKTVEGVHHAGVVTFHRIDASTSRVALQIEY
                     DPQGFIERVGALTNLDSVLANYDLGEFQKLAELTAESGGTRDA"
     aSDomain        138..443
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6J40_RS34140_Polyketide_cyc.1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="1.80E-14"
                     /label="I6J40_RS34140_Polyketide_cyc.1"
                     /locus_tag="I6J40_RS34140"
                     /protein_end="112"
                     /protein_start="10"
                     /score="46.1"
                     /tool="antismash"
                     /translation="VKAPVAITWALWSDVTQWPRFLSHVQRVDPIDERRFAWQLSLPGA
                     DKNFVAELTEVVTENRIAWKTVEGVHHAGVVTFHRIDASTSRVALQIEYDPQGFIER"
     gene            627..1265
                     /locus_tag="I6J40_RS34145"
                     /old_locus_tag="I6J40_34135"
     CDS             627..1265
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008736516.1"
                     /locus_tag="I6J40_RS34145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34135"
                     /product="glyoxalase"
                     /protein_id="WP_030190306.1"
                     /transl_table=11
                     /translation="MATTASTTVHLSLTSVTLEVADLEAAHRFHSALGVETRVRLRASG
                     AHTGGFRGFTLALTVPGPATVDGFLADAVGAGADVLKPATKSLWGYGGVVRAPDGTIWK
                     IATSAKKDTGPATRTVDAFVLLLGVEDVKATRQYYAARGLAVARSFGGRYTEFAADGPD
                     AVRLALYKRRALAKDLGVADDGTGSHRIVLGGTGGAFTDPDGFTWEHSA"
     gene            complement(1312..1809)
                     /locus_tag="I6J40_RS34150"
                     /old_locus_tag="I6J40_34140"
     CDS             complement(1312..1809)
                     /EC_number="3.5.4.33"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0052717 - tRNA-specific adenosine-34
                     deaminase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523437.1"
                     /locus_tag="I6J40_RS34150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34140"
                     /product="nucleoside deaminase"
                     /protein_id="WP_030190308.1"
                     /transl_table=11
                     /translation="MDFARRTIELARQNVAEGGRPFATVIVKDGEILAESPNRVAQTGD
                     PTAHAEILAIRDACTRLGTEHLTGTTIYVLAHPCPMCLGSLYYCSPDEVVFLTTREAYE
                     PHYVDDRKYFELATFYDEFAKPWQDRRMPMRYEERDEAVEVYRFWQERNGGERRVAGTP
                     AA"
     gene            complement(1912..2382)
                     /gene="cynS"
                     /locus_tag="I6J40_RS34155"
                     /old_locus_tag="I6J40_34145"
     CDS             complement(1912..2382)
                     /EC_number="4.2.1.104"
                     /GO_function="GO:0008824 - cyanate hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009636 - response to toxic substance
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cynS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140951.1"
                     /locus_tag="I6J40_RS34155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34145"
                     /product="cyanase"
                     /protein_id="WP_030117044.1"
                     /transl_table=11
                     /translation="MTHAQLDPTARETLAAEAVEAKILKDLSWQQIADAAGLSVAFTTA
                     AVLGQHPLPETSAKAVAELLGLGDDAAILLQTIPVRGSMPNRIPTDPTMYRFYEMLQVY
                     GTTLKALVHEQFGDGIISAINFRLDVKKVADPEGGERAVITLDGKYLPTKPF"
     gene            complement(2481..3059)
                     /locus_tag="I6J40_RS34160"
                     /old_locus_tag="I6J40_34150"
     CDS             complement(2481..3059)
                     /EC_number="4.2.1.1"
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238288.1"
                     /locus_tag="I6J40_RS34160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34150"
                     /product="carbonic anhydrase"
                     /protein_id="WP_030190310.1"
                     /transl_table=11
                     /translation="MQDLTEGVTRFQRDVFPAKADLFAALATRHTPHTLFIGCSDARVV
                     PELITGTEPGDLFVVRTAGNLVPAYAPEADGIAASIEYAVTALGVEDIVVCGHSACGAM
                     TALAENHDLSGAPAVATWLRHANASVARTSAAGDVSALVRQNVLAQLANLATHPSVANA
                     LARGKTTLHGWVFDIPTGRVQDLTAPQAA"
     gene            3186..4094
                     /gene="cynR"
                     /locus_tag="I6J40_RS34165"
                     /old_locus_tag="I6J40_34155"
     CDS             3186..4094
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="cynR"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950988.1"
                     /locus_tag="I6J40_RS34165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34155"
                     /product="transcriptional regulator CynR"
                     /protein_id="WP_030190312.1"
                     /transl_table=11
                     /translation="MASVELRHLRYLLAVAEHGNFTRAAEELHISQPTLSQQIKQLERT
                     VGVQLLDRTGRRVRLTDAGAVYTDHAGRALRDLAAAERAVHDVQNLSRGHLRLGATPTF
                     TAYLLGPLVAGLHARHPGIGLTLTEMPQDRIEAALLADDLDLGIAFTGHHLPGVAATAL
                     FTETLTLVTGAPADAGRGAPLPVQDLTGRQLALLSDDFATRGHIDAYFSRHRAVPRITV
                     EANSIQALTEIVRRTDLATVLPDAITHDHPHLTPVPLEPPLPARTVALLHREGAYLKAA
                     ARAFTRLIHEVVRTRGYTPAP"
     gene            5004..>5735
                     /locus_tag="I6J40_RS36440"
                     /pseudo=""
     CDS             5004..>5735
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558015.1"
                     /locus_tag="I6J40_RS36440"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS21 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKSDEEIMEILEAYDLTGSYRKAAELGGCDHHTVRRYVQLRGQGV
                     DPTERAVRSKLIDDFLPEVEELVERSRGRVGADAVHKKIAAMGLLAPTAPRAGPSPRRR
                     SPTWLGTAGSSGPGYPNR"
     misc_feature    5268..5270
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5760..>5852
                     /locus_tag="I6J40_RS36445"
                     /pseudo=""
     CDS             5760..>5852
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571795.1"
                     /locus_tag="I6J40_RS36445"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTPPHAKTWSPRGRTPVVRVRGRSRRRLSIA"
     gene            complement(6059..7108)
                     /locus_tag="I6J40_RS34175"
                     /old_locus_tag="I6J40_34165"
     CDS             complement(6059..7108)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377907.1"
                     /locus_tag="I6J40_RS34175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34165"
                     /product="glycosyl transferase"
                     /protein_id="WP_030190314.1"
                     /transl_table=11
                     /translation="MRVNFVSRGHGYGHAARDLRIMAAMRQVNPGIQIRLASAGSGADY
                     YRSRGVEAVDLGFDDADDMSEAASWRVWRFLYERADADLVVSDEFLTVPGFCRHVLDVP
                     NVLITDWFFAEYGQRDADSIMDDALEVVVPDFPEAHPVPPPTTAPVWFCGPLVDAFAPQ
                     RADARKALGLDEDALVMTVAAGGRPDRIAALRIQLQALQAWSRYAAPTDQLLLLADAPP
                     TRGRAPATPNVRWVGRTDRPELYYRAADVVLADALGFTGCELVANGVPVIASVTPDPGR
                     AVRAGFAERMDMLERTGLLTRTHADEDPAALWDKVREMRSRSDDPRPGGVWADPLDVAT
                     RILSHGRTS"
     misc_feature    complement(7093..7107)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.32"
                     /tool="antismash"
     misc_feature    complement(7094..7109)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.35"
                     /tool="antismash"
     gene            complement(7123..8241)
                     /locus_tag="I6J40_RS34180"
                     /old_locus_tag="I6J40_34170"
     CDS             complement(7123..8241)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377908.1"
                     /locus_tag="I6J40_RS34180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34170"
                     /product="hypothetical protein"
                     /protein_id="WP_030190316.1"
                     /transl_table=11
                     /translation="MSSPIRLSAAIMTHPARRARALALRDSLPELSLQVVEDPDPYGAG
                     SCSARTAVLAWGTAAHHATHHLVLQDDAVPVADLRERVLRTVGERPAAAISLYAEWASA
                     TSSAVHLAAWLGQPFAEVCDPYTPCIGLVLPAEAARELARARPEVPQDDVMIAGVLRRL
                     GVPEYVTVPNLVQHATEVSLTGNTPMGLRLAACYSTAPHSDTAPVVDARVDLLPCFSRS
                     YGRPYYLERDPGSVSGWSQRGLLETLRRRNVDVAALQRTAARRSAGLHRAQPDLRPDII
                     ISLWITAWLGGAELRRLLGDHAVDPSEVLDRRLGQIALANIGPGIFDQYMPPEQLLKLS
                     PVLQTFAHAAFTEGITASVRDGRFPDHRSLSG"
     gene            complement(8238..10004)
                     /locus_tag="I6J40_RS34185"
                     /old_locus_tag="I6J40_34175"
     CDS             complement(8238..10004)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964454.1"
                     /locus_tag="I6J40_RS34185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34175"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_030190318.1"
                     /transl_table=11
                     /translation="MNDSERIQMRALGRRVLRRFAAHKGGFALSLLTVVVSTGLGISGP
                     LFLRVIVDEAVPQRDRELLMWMCLGMLAVGIAQSGFFYLQSRLTNSIGLGVVHGLRVDV
                     YERVQSMPITFHAGRSGAEVQTRLASDIGGISDVITFTAQHALGALTMVITIGTAMLIL
                     SWPVAVVAIGLTLGLVIMNQHYAERQRLLAVEAQEHTSEMMRLTGEHLSLPGVLMGRTL
                     RCWDGQRDRFRASSSAIADLTIRERSMATSAESIISVSFAAIPPVVYWMAGGGFTSLSI
                     GTAIVLVVLQLQLAQPIQALLGLSTSVRRSLAHFDRIFEYIDLGPTAALPAPRNPHTGT
                     QVTAVGITLREVSYRYPESGRSTLRGIDLDFPAGSTTIIVGPTGSGKSTLGYLVAGLLE
                     PGAGTIRVSSGDEKPSETVLLVPQEPGIFNASFRDNLLLARPGATEAELREVLSRLALD
                     DLVSSFPEGLDTSVGERGYQLSGGERQRLGLARALLSDAPVVVLDEVTSALDWATARTV
                     QAALEELRGNRTTVVISHRLSGVKDTDRVVVLAEGLVAENGTHGELRTTPGRYSDLLRM
                     RDEDLSEAGTTP"
     gene            complement(10001..10717)
                     /locus_tag="I6J40_RS34190"
                     /old_locus_tag="I6J40_34180"
     CDS             complement(10001..10717)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512610.1"
                     /locus_tag="I6J40_RS34190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34180"
                     /product="nitroreductase family protein"
                     /protein_id="WP_030190320.1"
                     /sec_met_domain="PF00881 (E-value: 3.6e-10, bitscore: 38.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLIDETDLWSLAKRALAPADRPAEHMPPDGASAQDTSRISMSVR
                     LHDVLTARRSIRRFRQDSVPDTSLATLLDLATSTDRQMWPHGTAATTPQAWLVNGVTGT
                     SAARLRQYIPRRSTAGEPLSGEFTDHGDGPEPALLATRYAPGPATILICAKITDDIDSG
                     SDDAGADYRRALLRASAFGYNAWLSAVAAGLGGSVYGRSSPEVTRIVRRCTGTPARHLF
                     TLVLGHPAEAPQGSGS"
     gene            complement(10708..12414)
                     /locus_tag="I6J40_RS34195"
                     /old_locus_tag="I6J40_34185"
     CDS             complement(10708..12414)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964456.1"
                     /locus_tag="I6J40_RS34195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34185"
                     /product="hypothetical protein"
                     /protein_id="WP_234444825.1"
                     /transl_table=11
                     /translation="MTSTDSSLAAGGLRPRLRGGVAVSAADGQVVFSAGQIRKRIGGGD
                     ALRLLLPIASAMDGRRTVGDLAEATDLPYEAVAQAVALLVKQGLVLSGEVSSPRPLAAG
                     VVDYLELNAGTSASFRDASEVLQRLSRCTVLIVAPPSHTEAIRDDLAMSGVGAVHSAST
                     PAGVGNEVLDSLREAAGSLVVLYGPPRHIDGTDDFTDDCAARDIAVLHYAAHQGQVDLG
                     PLVHPRAMPCGRCFTSGYLAEFGSEQPAPADTATESVAAGLVVGEALAYLADIDNTRTS
                     QTLVRWTLPDSTVVRYAVAAEAGCTRCATTSRRSGERATVLEAYEDIVAADPLADRPQL
                     PVTASREKRLTALGKERESFATAPVIPLPPAANSVTPTGDGVPAASEAGPSGTEGSADT
                     AFVADLAAMVAGRRGDGEPLRWTASGGNLASVELYLMCADTVSGLPAHTLLKYDDIAHQ
                     LLVTRRTHGPALWRSMLDATGISDSPDVVLVVVGALWRLKLKYSTFALRLGHLDAGCAL
                     AQLHTVATDGGARLTVNDRWQPTLPTLLELKEDEQVMAVAGLWTPRSARCH"
     gene            complement(12398..13120)
                     /locus_tag="I6J40_RS34200"
                     /old_locus_tag="I6J40_34190"
     CDS             complement(12398..13120)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512608.1"
                     /locus_tag="I6J40_RS34200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34190"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_030117688.1"
                     /transl_table=11
                     /translation="MSATVRLNRLSVLGTGAFGARVSELLPNISGLAITRVGPEITGDM
                     LADTDAAVLVLDHPARRLARRFRQMASETGKPWLLVEFDHPVIRVGPYFDPAADPCLDC
                     FYAREDQHADKPAPLQGSAHKHEHNHDHAHAHAHAPDCSHAPAPASAQEGLGIEAAAGV
                     LPHQARIAVGLISLSLAEQVRGRVVTVDLRTAGIRSDQVIGCHGCPHCGDETERTLLSQ
                     QLNHLFRTVGGVTHDEHR"
     gene            complement(13099..14382)
                     /locus_tag="I6J40_RS34205"
                     /old_locus_tag="I6J40_34195"
     CDS             complement(13099..14382)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512607.1"
                     /locus_tag="I6J40_RS34205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34195"
                     /product="YcaO-like family protein"
                     /protein_id="WP_234444824.1"
                     /sec_met_domain="YcaO (E-value: 1.7e-60, bitscore: 204.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 6.7e-82, bitscore:
                     273.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDPLLSRYGVVGDAFDLSPSRYRGLPELSSYGVDLGSAFPGF
                     EAHSDDRVVAGGHALGDKDRARLLAIAEGCERYSGAQFGTEGVVTAAAHDLDGRVLDWS
                     RIPRLSDAEYAHPQCPLVPFDPAAPIRWVRGVDLRDGDPTWLPLSMAAYRSGRRFPAER
                     FVASISTGCAVHTDPTSAVFGGMSEVVERDMIAVLWLQKLPLPHIPFDVLDERELTLTA
                     WAHDRFLDTVLLDATSDIGLPTVYCLQTAPHDQTIRTMVGCGTGLTIQDAAYKALLEVT
                     CFRDSLHAEWEEPESFADYTDISDGAKYMGKPENAGHFAFLTDDHPDRPSFQDRGRYAA
                     DVTEGLTRAVRRFAELDMPVIAVDRTTTELASVGLYSATVVIPDLQPMSLVPLAQYHAH
                     PRLYSAPAAMGYRVLPVEELNPCPQPFA"
     gene            complement(14511..14741)
                     /locus_tag="I6J40_RS34210"
                     /old_locus_tag="I6J40_34200"
     CDS             complement(14511..14741)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6J40_RS34210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6J40_34200"
                     /product="hypothetical protein"
                     /protein_id="WP_109981233.1"
                     /transl_table=11
                     /translation="MLDTDPTPGGAVDLVVGDADESWEDLVRDLIAGPADPSRILTDCG
                     GNGCNCAGCVGCGLNCMSGGWKCATCGSACC"
     misc_feature    complement(14724..14737)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     misc_feature    complement(14847..14862)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            complement(14848..16665)
                     /locus_tag="I6J40_RS34215"
                     /old_locus_tag="I6J40_34205"
     CDS             complement(14848..16665)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018448.4"
                     /locus_tag="I6J40_RS34215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34205"
                     /product="threonine/serine exporter family protein"
                     /protein_id="WP_050494172.1"
                     /transl_table=11
                     /translation="MPRPPHPAPHPAGEHDATSTALAKLLRGTPYEHISFPAARVVPRA
                     EAQSILALAARVGRALFRAGAETQHIEAAVLAVAAAQGMREVTADINARIITLQYISQG
                     YDPLALMEVIGSEQARNLRHLAQLDLLVLDIAAGHHTPDQARQALDRAENSPAPSWWQS
                     QVGGALLSSMLCLLAAGTLRAALISPVLFLVAAAVERALAATRLAGFFATAARVAVLVA
                     LVTALVGLGIYSHSEAASTLAGNLILVLPLFTTVSLTEDMISGYRAMAAARAISLLSFF
                     TALATGFALVAFMLRNTESDARSTTLLALPVAVSLLTGAVGALGNTFYMGGTWRFVPPA
                     CALDSQLPVFLATGLATWAMGFAAAHLARRTPHSSGRRELACSIHCLVVHTECLSHTAA
                     HDHPQRLQQHAFNLSSQAPTPCGPEDIPRNRRRPDALLPGIHPRQARSGSSFNLKNDIP
                     GPRPRHHQIFITVKVLEPTDSPFPPSTVAAIGVLPAQEVTPVRQIPAVLQPGQRSRNVA
                     GTRGDPRTCRWEAAIPVLPGLDRPEVGVSWPAPWSISFTKQSALALIPHQGKQPQCPKV
                     TIRWSVINLCTHKSRRRNCSAPHISFTPS"
     gene            complement(16766..16942)
                     /locus_tag="I6J40_RS34220"
                     /old_locus_tag="I6J40_34210"
     CDS             complement(16766..16942)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6J40_RS34220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6J40_34210"
                     /product="hypothetical protein"
                     /protein_id="WP_157851895.1"
                     /transl_table=11
                     /translation="MVVPGVVLMNGGGFDGPEWSARVSLANLDYLDYLKIGHHMRTVFE
                     QYVEEWQGSSTGN"
     gene            17769..21245
                     /locus_tag="I6J40_RS34225"
                     /old_locus_tag="I6J40_34215"
     CDS             17769..21245
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015338.4"
                     /locus_tag="I6J40_RS34225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_34215"
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="WP_050494171.1"
                     /transl_table=11
                     /translation="MPLVFLVALALLTGTLTALGATVGAAPARAAAVDRTVLTWNMQGA
                     GSGSQNPAEKWYNLDHALLANPNTGRADIALLQEAGPMNVPETAVYRDTLTPTIIQGGV
                     PEPINQVEHYTWHGYHIYRAEWDLAGHRVNPAIVTREEATGAVLIGRVAPGVRPVLGLH
                     FGQDLYFTMHAGRGGNDAAAQSAKAWNWARTQNPPYSVMIGGDFNKEPSELGAISGLTM
                     LKTGKETHTGKKELDYALASDVNGPDDTHPVRLMEPGFFSDHSPVLLIPDHACPSNVAL
                     HGEGRTPLTRAAGPERCQDAVVSMGDSYISGEAGRWQGNGSNGQYSTKAKDGSSFGTDR
                     TAFNCSGSGNDEKCEHDPKRVYGDTGEGKEQCHRSDVAEIKSIGDGLGIPAERRLNIAC
                     SGATTEDILTRPFKGEMPQIEQLAILSRLYRLKYVVLSIGGNDLGFSKIAQDCVLGYEV
                     NRPCSAKGRGELGPKLAKVQDAVNKTVEAVQKTLADSGQNTKIIVQGYPNPVSSALNVR
                     YENKAWMREMSGGCPLTDPDVDWLHYEVVPGLNKQIASVAARQNVIFLDPLAALAGHQL
                     CGRGAAQADAGNTLSNPPAPTVSEWVRWIPGLSDGLPWTQGETQEAAHPNAFGQQAMGT
                     CLRQTIEKTQLSSEGYFTCVGSRGMSPDNVRVSEKKPAQQTLVGETHRMVLRNADSGDL
                     VDADWDGGDSYVRGEEEGQSDKQVWDVTAYEAGGQTVKQDSDEPQPILADITVKRGAFA
                     LASSEAPSNGEDPDSDQAHYWAQLAKNGRHNLNTWALSAPQRDGSVQYLYLRTDTEGKR
                     KVGGCLTQNPEVMTDKDRKSWLTVEPCGASTRQDWWLESPGSLPNPPPAPDGWEQRGTG
                     QLASSEHGTCISSGFFGTASLTECADDNIVQEWQPTAQIPLTPPRAADKPARGAAEALR
                     TRTTPKPIANGAFFLVNSASKDCLSPVDGGQSIVVDTCRDSGAQQWAWQGRTLRSVDSG
                     QCLVTDPDEGLSLADCVTVPGTLKGGIEPHSGNRVVMQSATGLAMELPGGDTAAGKKIV
                     GAAPAPEQDRQKWDLHVDAGPDGIWRLAPKLTADRHLSYNVIDREAALMDKVADNKGEQ
                     WRLEEVGGGWYRVVNSLDDTVLTASDVGKPLALTKPLNNLGQWWRFDCTCA"
     misc_feature    19032..19034
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21755..>21997)
                     /locus_tag="I6J40_RS36450"
                     /pseudo=""
     CDS             complement(21755..>21997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377478.1"
                     /locus_tag="I6J40_RS36450"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="SulP family inorganic anion transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="ELEVIDKGAGPIQAYLAGNATSLRLPKILDTLESPPQGRPMALDL
                     SGLLHLDHACRTALESWAEGHSATGVQPVKLTTTA"
     misc_feature    22166..22180
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
     gene            22818..>23672
                     /locus_tag="I6J40_RS36805"
                     /pseudo=""
     CDS             22818..>23672
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040036.3"
                     /locus_tag="I6J40_RS36805"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="DUF6248 family natural product biosynthesis
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRPGGVLGALVSCGIENGAGPAARRLKELLGSNGHHPQALDEVDA
                     GGDDFLLLSPGAAPYGHRLCTSTPTTSRPGGGRPGSEAGTSLPGRTRPREHRNPSTPLE
                     TRSMNETPNGAPPVIRRPQRTLTPEEHETVRGTAALNFQAGLIMGIIDPVPNLSPMSEA
                     EGEWVREQVWPAFLTDIDRKYPFGFWR"
     misc_feature    24067..24082
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.02"
                     /tool="antismash"
ORIGIN
        1 cggcggcgtg ccccgggccg tccgggaggc cgagttctgt tgagaggcgg caggctgggt
       61 acgagagggc gaagttgtcc acgtacccta cggaatggcg gtcgctcatg tcctcctcgc
      121 tcgtcgaaac catcgatgtc aaggccccgg tcgccatcac ctgggcgctg tggagcgacg
      181 tcacgcagtg gccgaggttc ctcagccacg tccagcgggt cgacccgatc gacgagcgga
      241 ggttcgcctg gcagctctcg cttccgggcg ccgacaagaa cttcgtcgcg gaactcaccg
      301 aggtcgtcac ggagaaccgc atcgcctgga agaccgtcga gggcgtccac cacgcgggcg
      361 tggtcacgtt ccaccggatc gacgcctcca cgagccgcgt cgctctgcag atcgagtacg
      421 acccccaggg gttcatcgag cgcgtcgggg ccctgaccaa cctcgattcc gtgctggcca
      481 actacgacct gggcgagttc cagaagctgg ccgaactgac cgccgagtcc gggggaacac
      541 gggacgcctg agcccccgag gggcggacga ggaccggtca ggatcaaaga agccgtggcc
      601 cgcgccccgg tcctagcctg agaggcatgg caaccacggc ttccaccaca gtccatttga
      661 gtctcacctc cgtcaccctc gaggtggccg acctcgaggc ggcccaccgc ttccacagcg
      721 ccctcggcgt ggagacgcgc gtacgtctgc gggcgtccgg tgcgcacacc ggcgggttcc
      781 gggggttcac cctggcgctc acggttccgg ggccggccac cgtcgacggg ttcctcgccg
      841 acgcggtcgg cgccggtgcc gacgtgctga agcccgcgac gaagtcgctg tgggggtacg
      901 gcggggtcgt acgggccccg gacggcacga tctggaagat cgccacgtct gcgaagaagg
      961 acaccgggcc cgccacccgg acggtcgacg cgttcgtcct gctgctcgga gtcgaggacg
     1021 tgaaggccac ccggcagtac tacgccgccc gcggactggc cgtcgccagg agtttcggcg
     1081 gcaggtacac cgagttcgcc gccgacggac ccgacgccgt caggctcgcc ctgtacaagc
     1141 gccgcgccct ggcgaaggac ctcggcgtcg cggacgacgg gaccgggtcg caccggatcg
     1201 tcctcggcgg aacgggcggt gccttcaccg acccggacgg cttcacctgg gagcactcgg
     1261 cctgagtggt ctcacctccc ggctgtgcgg ctcacgcggc aggtgcccgg ctcacgcggc
     1321 aggggtgccg gcgacgcgcc gctcgccgcc gttgcgttcc tgccagaagc ggtagacctc
     1381 gacggcctcg tcccgttcct cgtagcgcat cggcatccgc cggtcctgcc agggcttggc
     1441 gaactcgtcg tagaacgtgg cgagttcgaa gtacttccgg tcgtcgacgt aatggggctc
     1501 gtatgcctcg cgcgtggtga ggaagacgac ctcgtccggc gagcagtagt acagcgagcc
     1561 caggcacatc ggacacgggt gggcgagtac gtagatggtc gtgccggtca gatgctcggt
     1621 gcccagcctg gtgcaggcgt cgcggatggc gaggatctcc gcgtgggcgg tggggtcacc
     1681 ggtctgtgcg acccggttcg ggctctcggc gaggatctcg ccgtccttga cgatgacggt
     1741 cgcgaacggg cggccgccct cggcgacgtt ctgacgggcg agttcgatgg tgcgccgggc
     1801 gaagtccatg tgaggaacct ccggggacga agaggacggc ggggccgcct gtgggcggct
     1861 tcgccggagt gggggagcgg ggcggggcgc gtgaagtcgt accggtgtcg gtcagaaggg
     1921 cttggtcggg aggtacttgc cgtccagcgt gatgacggcg cgctcgccgc cctcggggtc
     1981 ggcgaccttc ttcacgtcga gccggaagtt gatcgcggag atgatgccgt cgccgaactg
     2041 ctcgtggacc agggccttga gggtcgtgcc gtagacctgg agcatctcgt agaagcggta
     2101 catggtcggg tcggtcggga tccggttcgg catggagccg cgaaccggga tggtctgcag
     2161 caggattgcc gcgtcgtcgc ccaggccgag cagctcggcc acggccttcg cggaggtctc
     2221 cggcaggggg tgctggccga gcacggcggc ggtggtgaag gccaccgaca ggcccgcggc
     2281 gtcggcgatc tgctgccagg agaggtcctt gaggatcttg gcctccacgg cctcggcggc
     2341 cagggtctca cgtgcggtcg ggtcgagctg ggcgtgcgtc atggcaggta tgtccttttc
     2401 tcggtggggt cactccgcgg gggcggtgcg gagtggtgat cggggtgggg ttggcggccg
     2461 gaaggccggt gccgggggcg tcaggccgct tgcggggcgg tcaggtcctg gacgcggccg
     2521 gtggggatgt cgaagaccca gccgtgcagg gtggtctttc cccgggccag cgcgttggcg
     2581 accgaggggt gggtggccag attggccagc tgggccagca cgttctgccg caccagggcg
     2641 gagacgtcac cggcggcgga cgtgcgggcc accgaggcgt tggcgtgccg cagccaggtg
     2701 gcgaccgccg gggcgccgct gaggtcgtgg ttctcggcca gcgcggtcat cgcgccgcac
     2761 gcggagtgac cgcagacgac gatgtcctcg acccccagcg cggtgacggc gtactcgatg
     2821 ctcgccgcga tcccgtcggc ttcgggggcg taggcgggca ccaggttccc ggcggtgcgg
     2881 accacgaaca ggtcacccgg ctcggtgccg gtgatcagct cgggtacgac gcgggcgtcc
     2941 gagcagccga tgaacagcgt gtgcggtgtg tgccgggtcg ccagggcggc gaagaggtct
     3001 gccttcgccg gaaagacgtc ccgctggaaa cgggtgacgc cctcggtcag gtcctgcatg
     3061 gtcactccct tcgaagcggt gaccggcccc ggtgggctgg tgagaccaac catgcatgac
     3121 ctgtgcttat agtgtccaag agcggatggg catcgctgcg atagatcgca tctatactca
     3181 gctccatggc ctctgtcgaa ctgcgtcacc tgcgctatct gctagccgtg gcggagcacg
     3241 ggaacttcac ccgggccgcc gaggaactgc acatctccca gcccacgctc tcccagcaga
     3301 tcaagcagct ggagcggacc gtgggggtgc agttgctgga ccgcaccggc cgcagggtgc
     3361 ggctcaccga cgccggcgcc gtctacaccg accacgccgg gcgtgcgctg cgcgatctcg
     3421 ccgccgcaga gcgtgccgtc catgacgtcc agaacctctc ccgcggtcat ctgaggctgg
     3481 gcgccacccc caccttcacc gcctatctgc tcggccccct cgtcgcaggg ctccacgccc
     3541 ggcaccccgg catcggcctt accttgacgg agatgcccca ggaccgcatc gaagcggccc
     3601 tgctcgccga cgacctcgac ctcggcattg ccttcaccgg gcaccacctc cccggtgtcg
     3661 ccgccaccgc cctgttcacc gagacgctca ccctcgtcac gggcgccccg gccgacgccg
     3721 gccggggcgc cccgctcccc gtacaggacc tcaccggacg ccaacttgcc cttctcagcg
     3781 acgacttcgc cacccgcggc catatcgacg cctatttctc ccgccaccgg gccgtcccgc
     3841 gcatcacggt cgaggccaac tccatccagg cgctcaccga gatcgtccgg cgcaccgacc
     3901 tggccaccgt cctgccggac gccatcaccc acgaccaccc ccacctcacc cccgtccccc
     3961 tcgaaccgcc cctgccggcc cgcaccgtcg ctctcctgca ccgggaaggc gcctacctca
     4021 aggcggcggc ccgcgccttc acccggctca tccacgaggt cgtccgcacg cgcggctaca
     4081 cgcccgcccc gtgacccgcc gactcggcgt acgggcggag gaccgcgaac cgggcggctc
     4141 catccggccc cgagaggtgc ccgcttccgg gtccgcgagc accggggcgg caccgggcgg
     4201 tgctgtgctg tgcgccccgg gccgcgtgac ccgtccgtga ggatggagct gaaccgaggg
     4261 atgaccgcca agggcctggc gtacgcggcc tccagagtga tcccggtggg accacccccg
     4321 caggcgcgga gacgaccgca gggaactctg ggacccgttc ccgaaggtcg agctaccccc
     4381 gcaggcgcgg ggacaacggc ccaacgcgcg gagcggcgcg gcgacgctgg gaactactcc
     4441 cgcgagtgcg gggacgacgc gcagatgact gtccggcgcg gggcggccga ggagctaccc
     4501 cggcgtgcgc ggggacgaca ccaacgtcga ctactggggc gtcaacacca cggagctacc
     4561 cccgcgtgcg cggggacgac acttgctgac ctgcggtgat gctagcgagt agcgcggttt
     4621 tccttcacct gcggtctgct ctggcggtct actcaggtct gttgtcggca gctgagccct
     4681 gtgtgcccgc gaactggctt gaggccctgc gggcacgagg aggacggaca gcccgatcaa
     4741 gtgccgcggg ggcggccgag ttacccccgc atgtgcgggg acggattctt ctatcaaggt
     4801 gcggaagctg ggacggatat tagcggcgcg gtgcgacagg ggtgtggatg attcctagtt
     4861 cgggggtaag gcagaaggct tagctgccgg caggggtgtc agaggacacg gcaaacttcc
     4921 cactggtgga catgaaatct ccccggtgac ggacagctaa actccccgca aacccgccca
     4981 gcccatgaca cagagtgggc ggggtgaaga gcgatgagga gatcatggag attcttgagg
     5041 cctacgacct caccgggagt taccggaagg cggccgagct gggcggttgc gaccaccaca
     5101 ccgtgcgccg atacgtgcag ctgcgcgggc agggggtcga cccgaccgag cgggcggtgc
     5161 ggtcgaagct gatcgacgac ttcctgccgg aggtcgaaga actggtcgaa cggtcccgcg
     5221 gcagggtcgg cgccgacgct gttcacaaga agatcgcggc gatgggctta ctggcaccga
     5281 ccgcaccacg cgccgggccg tcgccgcggc gaaggagtcc tacctggctg ggaaccgcag
     5341 ggtcttccgg ccctggatac ccgaaccggt gatgtggctg cagtgggact ggggcgaggg
     5401 cccacgtatc gactgctgac gcaccagcct gcggtgcgcg tggctggctt ggtcccgctt
     5461 ccgggtggtc atcccggtcc tcgacaagac cctagcccac catggcggcc tgcttggacg
     5521 cgacgttccg gcagctgggc ggggtcccga gctactgcct gaccgacaac gagaagaccg
     5581 tcacggtcga gcacgtggcc cggatcgcgg tccgcaaccc cgagctggtg ccgatcgccc
     5641 gctactacgg caccgtcgtc aggtcgtgca tgccggccga cccggcctcg aagggcggca
     5701 ccgaggcgac ggtccggatc gcgaagcggg acctcttcga ggacgaagcc ggcttctcca
     5761 tgacgccgcc gcacgcgaag acatggtcgc cacgcggccg caccccggtg gtccgggtcc
     5821 gcggccgttc ccgccgccga ctctccatcg ccaggcatcc acacggggct tgcgccggcg
     5881 gcggggcgca ccgccgcctt tcttctaccg ccacgcccgg ctccccgtca tacccccgtt
     5941 cgtcgtcgcg ctgtggtcga acggtcccgc tgacgagggc ctccgcttcg gcaactgcca
     6001 gcagggcgtg ggctctcccg gggatcggtc tgtgcgaggg gatcgcggaa ccgtctgctc
     6061 aactcgtacg gccgtggctg agtatccggg tggcgacatc caacgggtcg gcccagacgc
     6121 ccccggggcg cggatcatcg gagcggctgc gcatttcccg caccttgtcc cacagggccg
     6181 cggggtcctc gtcggcgtgg gtgcgggtca gtagaccggt ccgctccagc atgtccatgc
     6241 gctcggcgaa tccggcgcgc accgcccggc cggggtccgg ggtgacggag gcgatgaccg
     6301 gcacgccgtt ggcgacgagt tcgcagccgg tgaagcccag cgcgtcggcc agtacgacat
     6361 cggcggcccg gtagtacagc tccggccggt cggtccgccc gacccatcgg acgttggggg
     6421 tggcgggggc tcgcccgcgt gtggggggcg cgtccgccaa aaggaggagc tgatccgtcg
     6481 gggcggcgta tctgctccac gcctggagcg cctgcaactg gatgcgcagg gcggcgatac
     6541 ggtctgggcg accgcccgcc gccaccgtca tgacgagcgc gtcctcgtcg agcccgagtg
     6601 ccttgcgggc atccgcccgc tgtggtgcga aggcgtccac gaggggtccg cagaaccaca
     6661 ccggtgcggt cgtgggcggt gggaccggat gtgcctcggg aaagtccggg accaccacct
     6721 ccagcgcgtc gtccatgatc gagtcggcgt cgcgctggcc gtactcggcg aagaaccagt
     6781 ccgtgatcag cacgttcgga acgtcgagga catggcggca gaagccgggt acggtcagga
     6841 actcgtcgct caccacgagg tcggcgtcgg cacgctcgta caggaatcgc cacacgcgcc
     6901 aactcgcggc ctcactcatg tcgtcggcgt cgtcgaaacc gaggtcgacg gcctcgacgc
     6961 cgcgggagcg gtagtagtcc gctccgctcc cggccgaagc cagcctgatc tgtatcccgg
     7021 ggttcacctg gcgcatcgcg gccatgatcc tcaggtctct ggcagcgtgg ccgtagccat
     7081 gaccgcgtga gacgaaattg actctcatcg gtaagttcct cttcagccgc tgagcgaccg
     7141 gtggtcgggg aatcgcccgt cacggacgga cgcagtgatg ccctcggtga acgccgcatg
     7201 ggcgaacgtc tgcaggacgg gtgacagttt caggagttgt tccggcggca tgtactggtc
     7261 gaagattccg ggcccgatgt tggccagagc tatctgcccc agtctccggt cgagcacctc
     7321 ggacgggtcc acggcatggt cgccgaggag ccggcggagt tcggcacctc ccagccatgc
     7381 ggtgatccac aggctgatga tgatgtcggg ccgcagatct ggttgggccc ggtgcagacc
     7441 agccgaccgg cgtgccgccg tgcgttgcag tgcggccacg tccacgttcc gccgccgcag
     7501 tgtctcgagg agacctcgct gcgaccagcc cgaaacgctg ccggggtccc gttccaggta
     7561 gtacggcctt ccgtacgagc gtgagaagca gggcagcagg tccacccggg cgtccaccac
     7621 cggcgcggtg tcgctgtggg gtgcggtgga gtagcaggcg gccagccgca gccccatcgg
     7681 ggtattgccg gtgagactta cctcggtcgc gtgctggacc agattcggaa cggtcacgta
     7741 ttcggggacc ccgagcctgc gcagcacgcc ggcgatcatg acgtcgtcct gcggaacctc
     7801 cggtctcgcc ctcgccagtt cacgggccgc ctccgccggc agaacgagtc cgatacaggg
     7861 tgtgtacggg tcacacacct cggcgaaggg ttgtccgagc caggccgcga ggtggacggc
     7921 ggacgacgtg gccgaagccc attccgcgta gaggctgatc gcggcggccg gtcgctcacc
     7981 gaccgtacgc agcacacgtt cccgcaggtc cgcgacggga acggcgtcgt cctgtaggac
     8041 caggtggtgg gtggcatggt gagccgctgt cccccaagcg agcactgcgg tcctcgccga
     8101 acaggagccg gcgccgtagg ggtcgggatc ctcgacgacc tggaggctca actccggaag
     8161 gctgtccctg agtgcgaggg ctctcgccct gcgggcgggg tgggtcatga tcgccgcgga
     8221 gagtctgatg ggggaactca tggtgttgta cccgcctcgg acaggtcctc gtcgcgcatg
     8281 cgcaggaggt cggagtaccg gccgggcgtg gtacggagct cgccatgggt gccgttctcc
     8341 gcgacgagcc cttccgcgag aaccaccacc cggtcggtgt ccttgactcc ggacagccgg
     8401 tggctgatga cgaccgtggt ccggttgccg cgcagttcct ccagcgctgc ctgaactgtt
     8461 cgtgcagtcg cccagtccag agcgcttgtc acctcgtcga gcacgacgac gggtgcgtcc
     8521 gacagcagtg cgcgggccaa cccgagccgc tggcgttcgc cgccggagag ctggtagccc
     8581 cgttcgccga ccgaggtgtc cagtccctcg gggaaggagg agacgagatc gtcgagggcc
     8641 agtctggaca gcacctcacg cagttcggcc tcggtggcac cggggcgtgc gaggaggagg
     8701 ttgtcccgga aggaggcgtt gaagattccg ggctcctggg gcaccagcag gaccgtttcg
     8761 gacggcttct catctccgct ggacacccgg atcgtaccgg cgccgggctc cagcagtccc
     8821 gctacgaggt agcccagggt gctctttccg gagccggtcg gacccacgat gatggtggtg
     8881 gaaccggcgg ggaagtccag gtcgatcccg cgtagtgtgc tcctgccgct ctccggatag
     8941 cggtaggaga cctcgcgcag tgtgatgcct accgcggtta cttgggtccc ggtgtggggg
     9001 ttccgcggtg cggggagggc tgccgtcggc ccgaggtcga tgtactcgaa gatccggtcg
     9061 aagtgcgcca gtgaccgccg cacggacgtg ctcaggccga gcagtgcctg gatgggctgc
     9121 gcgagctgga gttgcagcac gaccagcacg atcgcggtgc cgatcgacag gctggtgaag
     9181 ccgccgccag ccatccagta gaccaccggc gggatcgccg cgaaggagac gctgatgatc
     9241 gactccgcac tggtcgccat ggagcgctca cggatcgtca ggtcggcgat ggccgacgac
     9301 gacgcgcgga accggtcccg ctggccgtcc cagcagcgca gcgtacgtcc catgaggacc
     9361 ccgggcagag agaggtgctc tccggtcagg cgcatcatct ccgatgtgtg ctcctgtgcc
     9421 tcgacagcca ggagccgttg tcgttcggcg tagtgctggt tcatgatgac cagccccagt
     9481 gtgagaccga tcgccaccac ggcgacgggc cagctgagga tgagcatggc ggtcccgatg
     9541 gtgatcacca tcgtcagtgc cccgagtgcg tgctgggcgg tgaaggtgat cacatcggag
     9601 atgccaccga tgtcgctggc cagccttgtc tgcacctctg ctcccgaccg gccggcgtgg
     9661 aaggtgatcg gcatcgactg cactcgctcg tacacatcca cccgcagacc gtggaccacc
     9721 ccgagtccga tcgagttcgt cagccggctc tgtaggtaga agaagccgct ctgggcgatc
     9781 cctacggcga gcatgcccag acacatccac atcagcagct cacggtcgcg ctggggcacc
     9841 gcctcgtcga cgatgacgcg aaggaacagc ggcccgctga tcccgagccc cgtggacacc
     9901 acgacggtca gcagggacag cgcgaagccg cccttgtggg cggcgaatcg ccgcagtacg
     9961 cgccggccga gagcgcgcat ctgtatccgc tcgctgtcgt tcacgacccg gacccctgcg
    10021 gggcttcggc agggtgcccc agcacaaggg tgaacaggtg cctcgccggt gtaccggtgc
    10081 accggcgcac gatgcgggtc acctcgggtg aggaacggcc gtacacgctg ccgccgagac
    10141 ccgccgcgac cgccgacagc caggcgttgt agccgaatgc cgacgcacgc agaagcgccc
    10201 gccggtagtc cgcgccggcg tcgtcggacc cgctgtcgat gtcgtcggtg atcttcgcgc
    10261 agatcaggat cgttgccggg cccggggcgt aacgcgtagc gagcagggcc ggttcggggc
    10321 cgtctccgtg gtcggtgaac tctcccgaga ggggctcgcc cgccgtggac cgccgcggga
    10381 tgtactggcg cagccgtgct gccgaggtgc ctgtgacgcc gttgacgagc catgcctgcg
    10441 gggtggttgc ggccgtaccg tgcggccaca tctgccggtc ggtcgacgtg gccagatcca
    10501 gaagggtggc gaggctggtg tcgggcaccg aatcctggcg gaaccggcgg attgatcgac
    10561 gggctgtcag tacatcgtgg agccgcacgc tcatggagat gcgggaggtg tcctgggccg
    10621 atgccccgtc gggaggcatg tgctcggcgg ggcggtcggc gggggctaga gcccgcttcg
    10681 ccagagacca caggtcggtc tcatcgatca gtggcatcgc gcgctccgcg gggtccacag
    10741 gccggccaca gccatgacct gttcgtcttc cttgagttcc agcagtgtcg gcagcgtcgg
    10801 ctgccagcgg tcgttcacag tgaggcgtgc tcctccgtcg gtggccaccg tgtgcagttg
    10861 cgcgagggcg caccctgcgt cgagatgtcc cagtctgaga gcgaaggtgc tgtacttcag
    10921 cttcagtctc cagagcgcgc ccacgacgac cagaacgacg tccggactgt ccgagatccc
    10981 ggtcgcgtcg agcatcgacc gccacagagc gggcccgtgg gtccggcggg tgacgaggag
    11041 ctggtgagcg atgtcgtcgt acttcaggag ggtgtgcgcg ggcagtccgg agaccgtgtc
    11101 cgcgcacatc agatacagct cgaccgacgc gaggtttccc ccggaggcgg tccatctgag
    11161 gggttcgccg tccccgcgtc gtcccgccac catcgccgcc aggtcggcga cgaacgccgt
    11221 gtcggcgctc ccctctgtcc cggaagggcc cgcctcagac gcggctggca ccccgtcacc
    11281 ggtcggggtt acggagttgg ccgccggtgg cagtggaatc accggtgcgg tggcgaacga
    11341 ctcgcgctcc ttgcccagcg ccgtcaggcg cttctcccgg ctggcggtaa ccgggagctg
    11401 gggccggtcg gcgagggggt ccgcggcgac gatgtcctcg tacgcctcaa gtaccgttgc
    11461 acgctcccct gagcggcggg acgtcgtcgc gcaccgtgtg cagcctgcct cggcagcgac
    11521 cgcgtaccgc accacggtgg agtccggcag ggtccagcgg acgagggtct gactggtgcg
    11581 cgtgttgtcg atgtcggcca ggtaggccag cgcttcgccc accaccagtc cggcggcgac
    11641 cgattcggtg gcggtgtcgg cgggggccgg ctgttcgctt ccgaactcag cgaggtagcc
    11701 gctggtgaag cagcgtccgc acggcatcgc tcgcggatgc accagcggac cgagatcgac
    11761 ctgcccctgg tgcgccgcgt agtgcagtac tgcgatgtcg cgggccgcgc agtcgtcggt
    11821 gaagtcgtcc gtgccgtcaa tatggcgggg cgggccgtac agcaccacga ggctgcccgc
    11881 cgcttcccgc aggctgtcga gcacctcgtt tccgaccccg gccggcgtgg acgcgctgtg
    11941 cactgctccg acgccgctca tcgccaggtc gtcgcggatg gcttccgtgt ggctcggtgg
    12001 ggcgacgatc agcaccgtgc atcgagacag gcgttgcagt acctcagagg cgtcgcggaa
    12061 cgaggccgag gtaccggcat tcagttccag gtagtcgacg acgccggccg ccagcggcct
    12121 cggcgacgag acctccccgg agaggacgag gccctgcttc accagcagtg ccacggcctg
    12181 ggccactgcc tcgtacggaa ggtccgtcgc ttcggcgagg tcgccgaccg tgcggcggcc
    12241 gtccatcgcc gacgcgatcg gcagcaggag ccgcagggcg tcccctccgc cgatcctctt
    12301 gcgtatctgt ccggccgaga agacgacctg gccgtcggcg gcggagaccg ccacccctcc
    12361 gcgcaacctg ggccggagac cgcctgctgc gagggaacta tcggtgctcg tcatgagtga
    12421 cgcctcccac ggtgcggaac aggtgattga gctgttgcga caggagcgtg cgttcggtct
    12481 cgtcgccgca gtgcgggcag ccgtggcaac cgatcacctg gtccgagcgg atccccgccg
    12541 tgcggagatc gacggtgacc acccgtccgc gaacctgctc ggccagcgac aggcttatca
    12601 ggcccacggc gatgcgggcc tgatgcggca ggactccggc tgctgcctcg atgccgagtc
    12661 cttcctgcgc cgacgctggg gccggggcgt gcgaacagtc cggtgcgtgg gcgtgggcgt
    12721 gggcgtggtc gtggttgtgc tcgtgcttgt gtgcggatcc ctgaaggggc gccggcttat
    12781 cggcgtgctg gtcctcacgg gcgtaaaaac agtccaggca ggggtcggcc gcaggatcga
    12841 agtacggtcc cactctgatg acggggtgat cgaactccac gaggagccac ggctttccgg
    12901 tctcggaggc catctgccgg aatcggcgtg ccaagcgccg ggcgggatgg tccagtacca
    12961 gcacggctgc atcggtatcg gcgagcatgt cgccggtaat ctccggaccg acccgggtga
    13021 tggccaggcc cgagatgttc ggcagcagtt cggacacccg ggcgccgaaa gccccggtac
    13081 cgaggacgga cagacggttc aggcgaacgg ttgcggacac gggttcaact cctcgacagg
    13141 cagtacgcga tatcccatgg ccgcaggtgc ggagtagagc cgaggatgcg cgtgatactg
    13201 ggcgagcggc accagggaca tgggctgcag gtccgggatg accacggtcg ccgagtacag
    13261 tccgaccgag gcaagttctg tcgtcgtccg gtccacggcg atcaccggca tgtccagctc
    13321 ggcgaacctc cggacagcgc gggtcagccc ctcagtgaca tcggcggcgt aacggccgcg
    13381 gtcctggaac gagggccggt cggggtggtc gtcggtgagg aatgcgaagt gcccggcgtt
    13441 ctccggcttg cccatgtact tcgcgccgtc cgagatatcg gtgtagtcgg cgaaggactc
    13501 gggctcctcc cactccgcgt gcagcgaatc gcggaagcag gtgacttcca gcaacgcctt
    13561 gtacgcggca tcctgaatcg tgagcccggt gccgcacccg accatggtgc gtatcgtctg
    13621 gtcatgcggt gcggtctgca ggcagtacac cgtgggcaga ccgatgtcac tggtggcatc
    13681 caggagcacg gtgtcgagga agcggtcgtg cgcccacgcg gtcagggtga gttcccgctc
    13741 atccagcacg tcgaagggaa tgtgcggcag cggcagcttc tggagccaca gaacggcgat
    13801 catgtcccgt tcgacgacct cgctcatgcc accgaagaca gcgctcgtgg gatcggtgtg
    13861 cacggcgcag cccgtcgaga tgctcgctac gaagcgctcg gccgggaatc ggcgccccga
    13921 ccggtaggcc gccatggaga gcggcagcca ggtggggtct ccgtcccgga gatccacccc
    13981 ccgcacccac ctgatcggtg cggccggatc gaacggaacg agggggcact gcggatgcgc
    14041 gtactccgcg tcggacagac gcggaatacg cgaccagtcg agcaccctgc catcgagatc
    14101 gtgcgcggcg gcggtcacta cgccttccgt gccgaactgc gcccccgagt agcgctcgca
    14161 cccctcggcg atggcgagca ggcgtgccct gtccttgtct cccagcgcat gtcctccggc
    14221 cacaacccgg tcgtccgaat gtgcctcgaa gcccgggaac gcgctgccga gatcgacacc
    14281 gtaggagctc agctccggca gacctcgata gcgggacggg gagaggtcga aggcgtcccc
    14341 gacgacgccg tagcgcgaga gcagcgggtc aagctgtttc atgttcacgt catccaggtc
    14401 aggtaaagaa cacggattcc ttgtccgggt ggtacccgcc ggcggcacca ccgccgacgg
    14461 gccgattcgc tacctaccgc ctcgaccgac ggggccggcc aggtacggaa ctagcagcac
    14521 gcgctgccac acgtagcgca cttccagccg ccgctcatgc agttcagacc gcagccgaca
    14581 cagccggcac agttacagcc gttgccaccg cagtccgtga ggatgcgtga ggggtccgcc
    14641 gggcccgcga tcagatcgcg gacgaggtcc tcccaggact cgtcggcgtc gccgacgacg
    14701 aggtcgaccg cccctcctgg cgttggatcg gtgtcaagca tctgctcttc ccttctctcg
    14761 cgaacagcac gtcatctctg gtgcaaaagt gtctgatcgg cgcaccggag tcaggctcaa
    14821 catagggtcg ctgatcactg tccaagctca agaaggtgtg aaggaaatat gaggtgccga
    14881 acagttgcgc cgtcgacttt tatgtgtgca aaggtttatg acggaccatc ggatagtgac
    14941 tttagggcac tgcggctgtt tcccctggtg agggatgaga gcgagagccg attgcttcgt
    15001 aaacgagata gaccacggag cgggccagga cacgccgacc tcggggcggt cgagcccggg
    15061 caacaccggg atggccgcct cccacctgca tgtccgaggg tcgccacgcg ttcccgctac
    15121 gttccgcgag cgctgacccg gctgtagcac tgcaggaatc tgacggacgg gcgtcacctc
    15181 ttgagccgga aggactccta tggccgccac agtcgaaggg ggaaacggtg agtcggtcgg
    15241 ctccagtacc ttgaccgtga tgaagatctg gtggtgacgg gggcggggcc ctggaatatc
    15301 attttttagg ttgaaactgg agccagacct tgcctgcctg gggtgtatgc ccggaagcag
    15361 tgcgtccggg cgtcgccggt ttcgcggaat gtcttcaggg ccgcaagggg tcggtgcttg
    15421 gctgctgagg ttgaacgcgt gttgttgtag gcgctgaggg tggtcgtgtg ctgcggtatg
    15481 gctgagacat tcggtgtgca ccacgaggca gtggatgctg caggccagtt ctctccttcc
    15541 ggaagagtgc ggggtgcggc gggcgaggtg ggcggcggcg aagcccatgg cccaggtggc
    15601 cagtccggtg gcgaggaaga ccgggagctg tgagtcgagg gcgcacgcgg gtgggacgaa
    15661 gcgccaggtg ccgcccatgt agaaggtgtt gccgagcgcg ccgacggcac cggtgagcag
    15721 ggagacggcg acgggcaggg cgaggagggt ggtggagcgc gcgtcgctct cggtgttgcg
    15781 gagcatgaag gcgaccaggg cgaagccggt ggccagggct gtgaagaagg acagcaggct
    15841 gatggcgcgg gcggcggcca tggcccggta tccgctgatc atgtcctcgg tcagggagac
    15901 agtggtgaac agcgggagca cgaggatgag gttgccggcc agggtgctgg ccgcttccga
    15961 atggctgtag atgccgaggc cgacgagcgc ggtgacgagg gccaccagga cggcgacgcg
    16021 cgcggcggtc gcgaagaacc cggccaggcg cgtggcggcg agagcgcgct ccacggcggc
    16081 cgcgacgagg aagagtacgg gggatatcag ggcggcgcgc agggtcccgg cggccagcag
    16141 gcacagcatg gaggagagga gcgcgccgcc gacctgggac tgccaccacg agggtgcggg
    16201 gctgttctca gcccgatcga gggcttggcg ggcctggtcg ggggtgtggt ggcctgcggc
    16261 gatgtcgagg acgaggaggt caagctgggc gaggtggcgc aggttgcggg cctgctcgga
    16321 gccgatgacc tccatgaggg ccagcgggtc gtaaccctgg gagatgtact gcagcgtgat
    16381 gatccgggcg ttgatgtcgg cggtgacctc gcgcatgccc tgggcggcgg cgacggcgag
    16441 gacggccgct tcgatgtgct gggtctcggc cccggcccgg aacagagcac gcccgacccg
    16501 ggcggccaga gcgaggatgc tctgggcctc ggcgcggggc acaacgcgcg ctgcggggaa
    16561 ggagatgtgt tcgtaggggg ttccgcgcag cagtttcgcc agggcggtgc tggtggcgtc
    16621 gtgctcgccg gccgggtggg gtgcggggtg cggcgggcgg ggcatgcgga actccgggtg
    16681 ctgggttggc cggcggatgg gcgggaacgg agcgtcgccg taccggtcgg ggtccggtac
    16741 ggcgacagct gtggggcggc ggcggtcagt tcccggtcga ggacccctgc cattcctcga
    16801 cgtactgctc gaagacggtc cgcatgtggt ggccgatctt gaggtagtcg aggtagtcga
    16861 ggttggcgag ggagacccgg gcggaccatt cggggccgtc gaagccgccg ccgttcatga
    16921 ggacgacgcc gggcacaacc acgcctccgc ccggacaatg gaacgcacag gcctcaccga
    16981 ggagggctac atccgcgagc acatccagcg cgccggccag cggcgggact cggtgaccca
    17041 ctccatcctc gaccacgagt accagcaagc aggacgagcc cggcccccgg cgagtagaga
    17101 agcggtgacc ggtgaactca cccagagccg cactgtcacc gtggcctcgg gcagcggtac
    17161 gcgggcgtgc gatgccgagg tactggggcg ggtcgatata cccggcctga gccggggcac
    17221 tcgtagccgg ccgtgcgctt gcgctgtacg cgccgccagg cagcatgagg cggttacggg
    17281 aggggggagt aaggccgcag gtggactccg ggtcccggag ccgcaacgat gagaagctga
    17341 ccggctgcat ccacagaagg tgcacgcggc cgacgccctg caggatccag cctgaccgac
    17401 tcctcggggg gacgcgcgat cagcagggcg ggacctcggc atcgagcacg ccggttttct
    17461 gccattccat catcaagggt tgatcgttgc tcccgggcgg cagcggactg cgaccatcga
    17521 tccaccagtc gcgcacctaa cgcaggttct gcgtagacgc ttctgtgcgt ccgcgtcggc
    17581 ggtgtacggc gaagcagtga tgcgacgggt ttcgttcacg ccacgtcctc tccggaccct
    17641 gaagcgtgtg cttagcatcc ttttggctgc agaagcagac caatcggctc gggaaggatg
    17701 cacggctaga tatggaacac ttactgtcac aacgcttccc cttacgaggg ttctgtgcgc
    17761 agcggcgaat gccgctcgtc tttctggtgg ccctcgcgct cctcacgggg acgctcaccg
    17821 ctctgggcgc gacagtcggt gccgcaccgg cccgggccgc ggccgttgac cgcacggttc
    17881 tcacctggaa catgcaaggc gccgggagcg ggagtcaaaa ccccgccgag aagtggtaca
    17941 acctcgacca cgccctgttg gccaacccga acactggtcg ggcggacatc gccctgctcc
    18001 aagaggccgg gcctatgaac gtcccggaga ccgccgtcta ccgggacacg ctgactccca
    18061 cgatcatcca aggcggagtc cctgaaccca tcaatcaggt cgagcattac acctggcacg
    18121 gatatcacat ctaccgtgcc gaatgggatc tcgccggaca ccgcgtcaac cccgccatcg
    18181 tcacacgaga agaggccact ggagcggtcc tgatcggccg ggtcgccccc ggtgtgcggc
    18241 ccgtactggg cctgcacttc ggacaggacc tgtacttcac catgcacgcc ggcaggggcg
    18301 gcaacgatgc ggcggctcag tccgccaagg catggaactg ggcacggacc cagaaccctc
    18361 cgtacagcgt gatgatcggg ggcgatttca acaaagagcc atcggagctc ggtgctatca
    18421 gcggcctcac catgctcaaa actggcaaag agacacacac tggaaagaaa gagctcgact
    18481 acgcgctcgc aagtgacgtc aacgggccgg acgacaccca tccagtccgg ctcatggagc
    18541 cgggcttctt ctccgaccat tcccccgtgc tgctgattcc cgaccacgca tgtccctcga
    18601 acgttgccct ccacggcgaa gggcggactc ccctcacccg ggccgccggc cccgagcgtt
    18661 gccaggacgc ggtggtgtcg atgggcgaca gctacatctc cggggaagcc gggcgctggc
    18721 aaggcaacgg ctccaacggc caatacagca ccaaggccaa ggacggctcc tccttcggca
    18781 ccgaccgcac ggcgttcaac tgctccggca gcggcaacga cgagaagtgt gaacacgacc
    18841 cgaaacgggt ctacggagac accggcgagg gcaaggagca gtgccaccga tcggatgtcg
    18901 ccgaaatcaa gtcgatcggt gacggactcg gcatcccggc ggagcggcgt ctcaacatcg
    18961 cctgctccgg cgccacaacc gaggacatcc tcacccggcc cttcaagggc gagatgcctc
    19021 agatcgaaca gttagcgata ctgtccaggc tgtaccgctt gaagtatgtg gtgctttcca
    19081 tcggcgggaa cgacctaggg ttctccaaga tcgcccagga ctgcgtcctg ggttacgagg
    19141 tcaaccgtcc gtgcagcgcc aagggacgcg gagaactcgg gccgaagctg gccaaggtgc
    19201 aggacgcggt gaacaagacc gtcgaggcag tccagaagac gctggcagac tcaggccaga
    19261 acacgaagat catcgtccag ggatatccca accccgtctc ctcggcactg aacgtgcgct
    19321 atgagaacaa ggcgtggatg cgggagatgt ccggcggctg cccactgacc gacccggacg
    19381 tggactggct ccactacgag gtcgtacccg gcctgaacaa gcagatcgct tcagtagccg
    19441 cgcggcagaa cgtcatcttc ctcgacccgc tggccgcgct cgccgggcat cagctgtgcg
    19501 gcaggggagc ggcccaggcc gatgccggga acaccctgtc caacccgccc gcccccaccg
    19561 tgagcgagtg ggtgcggtgg attccagggc tgtccgacgg actgccctgg acccagggcg
    19621 agacccagga ggcggcccac cccaacgcgt tcggtcagca ggcgatgggc acctgcctgc
    19681 gccagaccat cgagaagacc cagctctctt ccgagggcta cttcacctgc gtcggctcgc
    19741 gcggcatgag cccggacaac gtgcgagtct ccgagaagaa gcccgcccag cagaccctgg
    19801 tcggagagac acaccgcatg gtgctgcgaa acgccgacag cggtgatcta gtagacgccg
    19861 actgggacgg tggcgactcc tacgtccggg gcgaggagga ggggcagagc gacaaacagg
    19921 tgtgggacgt caccgcctac gaggccggcg ggcagacggt caagcaggac tccgacgagc
    19981 cgcagccgat cctcgccgac atcaccgtca agcgcggcgc cttcgccctg gccagtagtg
    20041 aggctccatc caacggcgag gacccggact ccgatcaggc ccactactgg gctcagctgg
    20101 ccaagaacgg ccgccacaac ctgaacacct gggctctttc cgcaccgcag agggacggct
    20161 ccgtgcagta cctctacctg cgtacggaca ccgagggcaa gcggaaggtg ggaggctgcc
    20221 tcacccagaa cccggaagtc atgacggata aggaccgcaa gagctggctc accgtggagc
    20281 cctgcggggc aagtacccgc caggactggt ggctggagtc accggggtcg ctgccgaacc
    20341 ccccaccagc gccggacgga tgggagcagc gcggcacggg gcagctcgcc agctccgaac
    20401 acggcacctg cataagcagc ggcttcttcg gaaccgcgag tctgacggaa tgcgcggacg
    20461 acaacatcgt ccaggaatgg cagcccaccg ctcagatacc gttgaccccg ccccgggcgg
    20521 cggacaagcc ggcccgggga gcggcggagg cgcttcggac gcgaacgacg ccgaagccca
    20581 tcgccaacgg cgccttcttc ctggtgaact ccgcctcgaa ggactgtctg agtcctgtcg
    20641 acggcgggca gagcatcgtg gtggacacat gcagggactc cggcgcccag cagtgggcct
    20701 ggcagggccg caccctgcga tccgtggaca gcggccaatg cctggtgacc gacccagacg
    20761 agggactgtc gctggccgac tgcgtcaccg tccccggcac gctcaaggga ggtatcgaac
    20821 cgcacagcgg caaccgcgtc gtcatgcaat ccgccaccgg tctcgcgatg gaactgccgg
    20881 gtggtgacac cgcagccggc aagaagatcg tcggcgcagc cccagcaccg gagcaggacc
    20941 gccagaaatg ggacctccac gtggacgccg gacccgatgg catctggcgt ctggcaccga
    21001 aactgaccgc tgaccggcac ctgtcgtaca acgtcatcga cagggaagcc gcgctgatgg
    21061 acaaggtggc cgacaacaag ggcgagcaat ggcgccttga agaggtaggc ggcggctggt
    21121 accgcgtggt caacagcctc gatgacaccg tcctgaccgc atcggacgtc gggaagccgc
    21181 tggccctcac gaaaccattg aacaacctcg gacagtggtg gcgcttcgac tgcacctgcg
    21241 cgtgacccga atcagagatt cgtcagcaga ggtggaaacc ctgtcgagca tttcgtcggc
    21301 tgtcttcatc caggcgaagg gtccagggtg gtcattccag ccgaccagcc atgcctggct
    21361 gtcgcgttca aagcccgcaa cctacaactc gacaccgcga caccggacag tttctcctag
    21421 agaaggaagg cacgaagccg tcctgggctg agctctgctg acggtaggcg cggccccacc
    21481 gcgccggcgc tgtatcgcga gcccccgacc gcgctgcggt cgggggcttc gcgctcagtg
    21541 tgccgccgga gggctactca gcgtcggggc cggtctcact gtccccctga ccaagggaac
    21601 ctctcacccc acttcaggct cgccgccaac agagacgcca ttggccaccg ccgacggaac
    21661 cgccacgtcc ccgcggcggc tgcgtggcca cccctgtcct caatgggcgc cttccgagcc
    21721 tggaaagaca aggcggggct tcgggtcact ctgttcaggc tgtggtggtg agcttcaccg
    21781 gttggacgcc tgtcgcactg tgtccttcgg cccagctctc cagcgctgtg cggcaggcgt
    21841 ggtcgaggtg gagcaatcct gaaaggtcga gtgccatcgg gcggccctga ggtggggact
    21901 ccagagtgtc gaggatcttt ggcaggcgga gggaagtggc gttgcccgcc agatacgcct
    21961 ggatgggacc tgcgcccttg tcgatgactt cgagctcctg ggtgcgcggc cccgtggccg
    22021 gatccgccga cttccccgtc tccgacgact tccacgacta cgccaggacc gtgcgcaccg
    22081 gctgagaggc cggaccggcc gggggagcgg ggcgggagtc ccgctgcccc ggccggagtt
    22141 gacccagact ccaaaaagtg agagtattag ttacgtcgat agggggcggg aatctcctac
    22201 cggtgccggc ccccgggtca cgccgagaac ctcactagga gcgacaccac catgccgatg
    22261 atctccaagg ccgtctgcca ggagctgcaa ctcgccgcgc gcgacgggcc gacggtccga
    22321 ctgcgcgagg tccgtgacgt gacgctggag ggcaaggtcc acagggtcct cgccaggtcg
    22381 gtgccacctg gagctatagc ctccgggcct acgttttcgc cgacctctac ccctacggcc
    22441 aggcggccga ggtgatccag cagatcgtcg cccgccagac cgccgtccgg ccggaacgag
    22501 ggatggtctc gtgcccggcg tcgatcgccg agctcctgtg gagcgaactc ccgcaggact
    22561 cgggtctgct gggactggag ccctctgccg ggcacggggc tctcgccgcc gaaggagccc
    22621 gcctcggcta ctcggtggac tgctacgagg tggagggcca ccgggcggcg gacatcaccc
    22681 gggccggagt cgcccgcagc gtctccgtgg ccgacttcct taccgtcgag ccccggccgg
    22741 agtaccacgc cgtcgccatg tacccgcccc accggatcaa cctcgccgcc gcacacgtgc
    22801 tgcacgccta caacttgatg cgcccgggag gagtcctcgg cgccctggtc tcatgcggca
    22861 tcgagaacgg ggcggggccc gcggcgcgac ggctcaagga gctgctgggc agcaacggcc
    22921 accaccccca agccctggac gaggtggatg ccggtgggga cgacttcctg ctgctgtccc
    22981 cgggggcagc cccgtacggg cacagattgt gtacctctac gccgacgacg agtagaccgg
    23041 gcggcggccg gccggggagc gaggcgggaa cctcgctccc cggccggacc cggccccgag
    23101 agcaccgaaa cccctcaacc ccgctggaga cccgcagcat gaacgagacg ccgaacggcg
    23161 cgccgcccgt catccgccga ccgcagcgca ccctcacccc cgaggagcac gagaccgtac
    23221 ggggcaccgc ggccctgaac ttccaggccg gcctgatcat gggcatcatc gacccggtgc
    23281 ccaacctgtc accgatgagc gaggccgagg gggagtgggt ccgcgagcag gtgtggcccg
    23341 cgttcctcac ggacatcgac cgcaagtatc cgttcggctt ctggcggtga agcacgtgtg
    23401 agaagggcac ctgctggaac tgcctcgccc gccgctgcga cctgtgcgtc caccgccagg
    23461 agggcggccc gtacggggac cgcaacttcg agtgggtgca caacgctcgg gggatggtgg
    23521 tcgcggagtt gatcctgcgg cccgacggcg ctccgtgcgt gtggtggtgc aggtgcccgt
    23581 gtgccaagac cggccccgcc ccccgaccgt cccgcgcgag gccgacggcg gcagaagcgg
    23641 gcggcggaga gcggccccga gccctgcccg ccggcggccg acgcgcaggc ggacgaggca
    23701 gttgtgccgg aggcggcgga gcagtgcacc ctgttctgac cgggcggccg gggcgacccg
    23761 gagccggacg tcgagcggcc cggcggggga ttggtgaatc gggaaccccc gccgggccgt
    23821 cggtccggcc accgagggtc ctcaacaaac ccattaaccg aacagcatca tcttacccag
    23881 caccgacacc accaggagca cagcgtgaga accgtcgacg gccgccagtg ggcgaaccgc
    23941 gaggacctga tcgagcacag cggctacagc cgggccaccc tcggcgcgct gtggcgcgac
    24001 cgcgagacca acagccaccc cccggcccgc acgatcgacg gcgtcatgca ctgggacctg
    24061 gaggagtgga ccggctggtt cgccagacac tgcgagcgcc cccgagacct gtccaaggtg
    24121 gaccggaagg gcgacccgga cgagatgctc ccgccgtcgg ggcaggccag cgtcctcggt
    24181 gtcgaccggg cccggatcac ccagtacaag aagaagccgc cgcccgggtg gccggagccg
    24241 attcacaccg agcagctggc caagagcgtc cgtgagtacc gcactcggcg ccagctctgg
    24301 gagttcgccg acaacccggc cggcggattg gggaccaagg gcggtcggcc gggccgctcc
    24361 aagcggacga agtccgaggg gg
//
