LOCUS       NZ_CP070260            22842 bp    DNA     linear   CON 30-MAR-2024
DEFINITION  Streptomyces californicus strain FDAARGOS_1210 chromosome.
ACCESSION   NZ_CP070260
VERSION     NZ_CP070260.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces californicus
  ORGANISM  Streptomyces californicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7919564)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7919564)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2021) Institute for Genome Sciences, University of
            Maryland School of Medicine, BioPark II, 801 W. Baltimore St., Suite
            619, Baltimore, MD 21201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 8.0.0, HGAP v. 4
            Genome Coverage                   :: 624.55x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016906265.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 09:02:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,240
            CDSs (total)                      :: 7,147
            Genes (coding)                    :: 7,032
            CDSs (with protein)               :: 7,032
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 115
            CDSs (without protein)            :: 115
            Pseudo Genes (ambiguous residues) :: 0 of 115
            Pseudo Genes (frameshifted)       :: 36 of 115
            Pseudo Genes (incomplete)         :: 97 of 115
            Pseudo Genes (internal stop)      :: 12 of 115
            Pseudo Genes (multiple problems)  :: 27 of 115
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:25:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4502876
            Orig. end                         :: 4525718
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070260.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22842
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="20"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22842
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22842
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12842](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12842
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(989..2410)
                     /locus_tag="I6J40_RS19510"
                     /old_locus_tag="I6J40_19500"
     CDS             complement(989..2410)
                     /EC_number="2.4.1.15"
                     /GO_function="GO:0003825 - alpha,alpha-trehalose-phosphate
                     synthase (UDP-forming) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018101576.1"
                     /locus_tag="I6J40_RS19510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19500"
                     /product="trehalose-6-phosphate synthase"
                     /protein_id="WP_030189675.1"
                     /transl_table=11
                     /translation="MVSEHTPSTTSSASPASQVLVASNRGPVSYTLGEDGTLDAKRGGG
                     GLVSGLSAVDDKLWVCAALGDGDREAVRRGVGEPGVRMLDIDAEVHADAYNGIANSVLW
                     FVHHMLYQTPVEPVFDAEFRRQWAAYETYNRAFARALAEEAEPGASVLVQDYHLALVPG
                     MLRELRPDLRIGHFSHTPWAPVDYFRLLPDDIAEQLLHGILGADRAAFLTRRWADAFIG
                     CCTEILGGTGRTRIGVHGLGADADFLRERAHEPDVDERMAALREQVGEGRKTIVRVDRT
                     ELSKNIVRGLHAYRALLEARPEWRERVVHIAFAYPSRQDLAVYRDYTAAVQSLATEING
                     QYGTESWTPVVLHVKDDFARSLAAYRLADVALVNPIRDGMNLVAKEVPVVSDQGCALVL
                     SREAGAYEELGEDAIVVNPYDVTGTADALHEALTMSGDERSGRTKRLAEAATALPPQAW
                     FLEQLEALRQDELPR"
     gene            complement(2526..3476)
                     /locus_tag="I6J40_RS19515"
                     /old_locus_tag="I6J40_19505"
     CDS             complement(2526..3476)
                     /EC_number="2.4.1.266"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511020.1"
                     /locus_tag="I6J40_RS19515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19505"
                     /product="glucosyl-3-phosphoglycerate synthase"
                     /protein_id="WP_030189676.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.2e-10,
                     bitscore: 37.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEEVGRWLTGRSWSSADRPLNRLTEARAADPGRTTVSVVLPALN
                     EEATVGAIVATIRRELMERVRLVDELVVIDSGSTDATAAVARAAGARVVHRDAILPRIP
                     ALPGKGEVLWRSLLVTSGEIVCFVDADLRDFSADFVSGTVGPLLTDPAVQFVKAMYDRP
                     LGDAAGQGGRVTELVARPLLNLHWPQLAGFVQPLGGEYAVRRSLLERLPFPVGYGVELG
                     LLVDALHTVGLDALGQVDVGVRVHRHQDGQALGRMAAAIYRTAQLRLSRGHLVRPALTQ
                     FERGEDGFVPRTYAVDTEERPPMREIAEYAARRAA"
     regulatory      3630..3757
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            3777..5087
                     /gene="thrC"
                     /locus_tag="I6J40_RS19520"
                     /old_locus_tag="I6J40_19510"
     CDS             3777..5087
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056010.1"
                     /locus_tag="I6J40_RS19520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19510"
                     /product="threonine synthase"
                     /protein_id="WP_030189678.1"
                     /sec_met_domain="PALP (E-value: 2.2e-61, bitscore: 206.5,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQTVAGTADTTAAATSNVDLGPAAALSCRECGERFELGPLFAC
                     ASCFGPLEVAYELPTGAPEELRKRIEAGPDNIWRYAPLLPVPADVAEKPNLNPGFTKLV
                     KADNLARELGVTGGLYVKDDSGNPTHSFKDRVVAIAVEAARAFGFTTLSCSSTGNLAGA
                     VGAAAARAGLRSCVFIPHDLEQGKVVMAAVYGGELVGIEGNYDDVNRFCSELIGDPLGE
                     GWGFVNVNLRPYYGEGSKTLAYEICEQLGWRLPDQIVIPIASGSQLTKIDKGFQELIKL
                     GLVEDRPYKIFGAQAEGCSPVSAAFKAGHDVVRPQKPNTIAKSLAIGNPADGPYVLDIA
                     RRTGGAVEDVTDEQVVDAIKLLARTEGIFGETAGGVTVGVTKKLVEAGVIDPTLTTVVL
                     NTGDGLKTLDAVSATSQATATIKPSLDAFRAAGLASA"
     gene            5123..5401
                     /locus_tag="I6J40_RS19525"
                     /old_locus_tag="I6J40_19515"
     CDS             5123..5401
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265553.1"
                     /locus_tag="I6J40_RS19525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19515"
                     /product="MoaD/ThiS family protein"
                     /protein_id="WP_030113311.1"
                     /transl_table=11
                     /translation="MSVKVRIPTILRTYTGGQAEVTAEGAKLSEVIESLEKDHPGIAAR
                     VLDDQGKLRRFVNVYVNDDDVRFEGGLDAATPDGAGVSIIPAVAGGC"
     misc_feature    complement(5410..5424)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            6031..6237
                     /locus_tag="I6J40_RS19530"
                     /old_locus_tag="I6J40_19520"
     CDS             6031..6237
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967346.1"
                     /locus_tag="I6J40_RS19530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19520"
                     /product="cold-shock protein"
                     /protein_id="WP_003967346.1"
                     /transl_table=11
                     /translation="MAQGTVKWFNAEKGYGFIAVDGGADVFVHYSAIQMDGYRTLEEGQ
                     RVEFEISQGQKGPQADMVKLAVG"
     misc_feature    complement(6079..6092)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    6703..6718
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    complement(6706..6721)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            6872..8494
                     /gene="groL"
                     /locus_tag="I6J40_RS19535"
                     /old_locus_tag="I6J40_19525"
     CDS             6872..8494
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="groL"
                     /gene_functions="other (smcogs) SMCOG1299: chaperonin
                     GroEL"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133870.1"
                     /locus_tag="I6J40_RS19535"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19525"
                     /product="chaperonin GroEL"
                     /protein_id="WP_030119959.1"
                     /transl_table=11
                     /translation="MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGA
                     PTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLR
                     NVAAGANPMALKRGIEKAVEAVSAALLEQAKDVETKEQIASTASISAADTEIGAKIAEA
                     MDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIVN
                     SKIGSVKDLIPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIKGTFKSVAVKAPGFGD
                     RRKAMLADIAILTGGTVISEEVGLKLENAGLDLLGRARKVVITKDETTIVDGAGDSDQV
                     QGRVNQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
                     NAKAAVEEGIVAGGGVALLQASAVFEKLDLTGDEATGANAVKLALEAPLKQIAVNGGLE
                     GGVVVEKVRNLAVGHGLNAATGEYVDMIAEGILDPAKVTRSALQNAASIAALFLTTEAV
                     IADKPEKAGAAAPGGMPGGDMDF"
     gene            8711..9316
                     /locus_tag="I6J40_RS19540"
                     /old_locus_tag="I6J40_19530"
     CDS             8711..9316
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126485.1"
                     /locus_tag="I6J40_RS19540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19530"
                     /product="hypothetical protein"
                     /protein_id="WP_239589740.1"
                     /transl_table=11
                     /translation="MDTGAGGAGRTGGDPVGGEGRTRGGARPAGRGGGAGGRRLAGLSL
                     LLGGGALVVLGLMVVVTGTGLSGALGMRVETFGRIDCRDTRTQKGQTVRHCFGESPAQQ
                     RANRAELKQVDLEMLRAHLDGVPRAPELQRTRILFTDHDGRTDPDTVTATQVFDGGRWY
                     AHSSTLVGYGMIPLLLGAGTAAWGGYRLRGRREGAGAG"
     misc_feature    9549..9564
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.0"
                     /tool="antismash"
     misc_feature    9724..9738
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            9828..9950
                     /locus_tag="I6J40_RS19545"
                     /old_locus_tag="I6J40_19535"
     CDS             9828..9950
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489031.1"
                     /locus_tag="I6J40_RS19545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19535"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_018511015.1"
                     /transl_table=11
                     /translation="MKQQKKAYVKPSLFKQGDFSKKTAGYFYGSYKEYWVRRII"
     CDS_motif       9828..9899
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKQQKKAYVKPSLFKQGDFSKKTA"
                     /locus_tag="I6J40_RS19545_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9900..9950
                     /prepeptide="core"
                     /locus_tag="I6J40_RS19545_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="0.20"
                     /molecular_weight="2082.4"
                     /monoisotopic_mass="2081.0"
                     /core_sequence="GYFYGSYKEYWVRRII"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKQQKKAYVKPSLFKQGDFSKKTA"
                     /leader_location="[9827:9899](+)"
     misc_feature    9959..9974
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.15"
                     /tool="antismash"
     gene            10001..12121
                     /locus_tag="I6J40_RS19550"
                     /old_locus_tag="I6J40_19540"
     CDS             10001..12121
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610346.1"
                     /locus_tag="I6J40_RS19550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19540"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_031014763.1"
                     /sec_met_domain="Asn_synthase (E-value: 3.6e-20, bitscore:
                     71.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGHLRDYFVVLPDSAAGAAVAGRLPVRESTGRSAAQESTGPAAA
                     GGDGLTVLHPSGRPWVVARTAFREVSHLRRGDDALVLIGPDRVPESVLAGLLEGARDRA
                     GLERRLARRPGLHHVIARLSGQTWIRGTASGLRRIYHARHPEAGTIASDRPAVLARLID
                     APLDDGALALRMLDFLPHPLSRRVVWRGVHETGAGYGLALPVAAPGTAAVPGPAEYRWW
                     EPPAPELPLAEGARALGEAIAASVRAHVGGHDRISCELSGGLDSTALTFAARATGPRRL
                     SLLTVAARDRYSEDETWARRAVELAGQDDHPKQSAQTRHADEPTAVGRSTATGGRPAAA
                     GRSTAADRPADPGRPAGPERDADPDLEHRVIPADDAPYFYADLASCAAELNDEPLPVAP
                     GRARAELLLGRARATGSRYHLTGYGGDELFLGLPHAYQDLFHGNPFTAWNHLGGLRHQL
                     GWPLLPTVKALLNRSSFPRWLAGAVTAEAQPVARTPLLSWGVRQSLRPWFTELANSLII
                     EEFRAAAEHAEPIDPWRGRHVDIDAVRMGARHFQAMEDIGTTIGLPVAAPFYDDRVLEA
                     TLAVRLPDRISPWRYKPLLVEAMRGVVPDALLARTTKDHMSSDEHQGLREHGPELAELW
                     TGSRLAERGLVDGRQLLRLAAEPFSPVLVEHSISSTVAGETWLRTAENAWPTAPSRSDS
                     TSPLTRTSEAIL"
     aSDomain        12118..12363
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_I6J40_RS19555_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.10E-27"
                     /identifier="RREFam002.1"
                     /label="I6J40_RS19555"
                     /locus_tag="I6J40_RS19555"
                     /protein_end="82"
                     /protein_start="0"
                     /score="86.0"
                     /tool="antismash"
                     /translation="MKLRKGIAVTTTEYGGVLLDENDGSYWQLNDTSVIVVDTLAAGHT
                     PEIAVERIVAAFDVERAEAESDVAELTRQLVEAKILH"
     gene            12118..12369
                     /locus_tag="I6J40_RS19555"
                     /old_locus_tag="I6J40_19545"
     CDS             12118..12369
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958805.1"
                     /locus_tag="I6J40_RS19555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19545"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_030113304.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.1e-25,
                     bitscore: 86.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.2e-11, bitscore: 43.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRKGIAVTTTEYGGVLLDENDGSYWQLNDTSVIVVDTLAAGHT
                     PEIAVERIVAAFDVERAEAESDVAELTRQLVEAKILHA"
     gene            12366..12842
                     /locus_tag="I6J40_RS19560"
                     /old_locus_tag="I6J40_19550"
     CDS             12366..12842
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610348.1"
                     /locus_tag="I6J40_RS19560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19550"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_030113303.1"
                     /sec_met_domain="PF13471 (E-value: 1.3e-24, bitscore: 85.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEMTMPRRGAGAGGIRLRTAIAAAFVLARLKPGRLRRVLDRCA
                     RGARPASYAETLEVFEAVVSTSRRCAGRYGCLPRSVAIALACRMSGVWPDWCAGVRAAP
                     PFAPHAWVQAGGRTVGEQAEPADLRPLMTVTADGGDPGGHGDGDDGGRGAERAA"
     gene            13069..14796
                     /locus_tag="I6J40_RS19565"
                     /old_locus_tag="I6J40_19555"
     CDS             13069..14796
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942874.1"
                     /locus_tag="I6J40_RS19565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19555"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_106981291.1"
                     /transl_table=11
                     /translation="MRLLLSRVRPHQGVLLRAGLLSLAGSGAGLAMPLTAKYAVDAFAA
                     DRSPAGPLVALTALVLVGACLSAYGRYLMSRTGEGVVLRARDQLVARIMRLKVPAVDRL
                     TPGDLQSRVTSDTTLLRTVLSSGLVESFNSVLMLLGTIGFMAYMDLTLLGVTLVVIVGI
                     GAVTSLLMPRIQRAQLRAQESVGAMGAALDRVLQAFRTVKASGAEERETAAVAAAARHA
                     HDRGVTVAKWASVTDVTMMMSIQLAFLAVLGVGGARVASGSLEISALIAFLLYLFYLMG
                     PIGGLVEGWTGLQSGLAAVRRIDEVESLPGEPEPETAPVPVRDRGPARPLGVAFQDVVF
                     GYGDERAPAHQGVTFDVPAGGMVALVGPSGAGKSTVFSLLERFYDHDGGTISVAGRNIR
                     DWPLAELRGALAYVEQDAPVLAGTLRENLLFAAPEADEEALASAVARTRLDALVARLPE
                     GLDTAVGHRGVTLSGGERQRIAIARALLRRPRLLLLDEVTSQLDAVNEQALRDVILELA
                     EQTTVLVIAHRLSTVRHADRIVVLEEGRVRRAGTHEELLAEDDLYRELATTQLAADAR"
     gene            14838..16823
                     /locus_tag="I6J40_RS36220"
     CDS             14838..16823
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6J40_RS36220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_063754456.1"
                     /transl_table=11
                     /translation="MDAELSARFAAEVDWSKVVDPYTPWQHGPDLLERVWSPDARTADD
                     AHADLHVACCGDGSSVLPAAVEVLPFLVRAAGDPDVRVRPQILDTLAVLGRAGNAARPS
                     APGPKPGGWRPTAPAAWPAAWYRATDALLPGLADGDEAVRAGVAAVLAQATGRADDLVD
                     RLRSRFEDEPEQPVAEQLVLSVGELAPHAVNRRAAAVAWLRQRMDDVGKGEEPDIDQDV
                     DTWIAWTGQHGHDVRLSAVAALRRALPGRPDPAYARTTVDALIRPSPYDAARFGGHRSL
                     YVTRAVDADARLDEDLPGRLALARELLRQDSAAHHESGLRIAASLMSRWRSAVPELLPD
                     VAEFVDAPDEVNRSFALRVLAMCGTAARPWSDRAAAHLSEDDEPYEPARRHAVWMLSRA
                     GDERCVEPLIDGLSSGRATGFSASPPYLSTCDWEKSDLNYTEALRPFAVRAEALPVPPP
                     TRGGVPAAADRDRRSSIPQDATERARVRWREAGDPNEVVHGLLELTANSARKAYATPGG
                     VKPLLLLAEIAATHPPVADEVAGRLAATARARVEGDCRFEAMTLLRALWELTRDGHRVA
                     PALVDLVRICPPGVAPPTIVEAVELLAEVAAADPPAATAVAPRVRRLLDTDERPVRHDQ
                     WRAVLSDDALLAAVRTVVGAAQAAGA"
     misc_feature    16885..16900
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.58"
                     /tool="antismash"
     misc_feature    complement(16937..16952)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            17033..17536
                     /locus_tag="I6J40_RS19575"
                     /old_locus_tag="I6J40_19565"
     CDS             17033..17536
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489040.1"
                     /locus_tag="I6J40_RS19575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19565"
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_030113298.1"
                     /transl_table=11
                     /translation="MTVEEFEEFYAQAVARLTGQLYVMTGDLQEAQDVVQEAFVKAWVR
                     RGRLEREGQPEAWIRTVAWRLAVSRWRFRRRSADAWGLGSGRSPEHVEPPGPDHVALVA
                     ALRELPAQQRRTLTLHYLCDLTVEQIAGETGLSTSTIKTHLVRGRAALAHRLQDPRIEE
                     ARDV"
     misc_feature    complement(17048..17061)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.98"
                     /tool="antismash"
     gene            17529..18020
                     /locus_tag="I6J40_RS19580"
                     /old_locus_tag="I6J40_19570"
     CDS             17529..18020
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958798.1"
                     /locus_tag="I6J40_RS19580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19570"
                     /product="hypothetical protein"
                     /protein_id="WP_030113297.1"
                     /transl_table=11
                     /translation="MSERRDPLRSLFREAGEFGQIRAEADDAARITQRGMRAQRRRMAA
                     VAVGVCLVVGGGGAAAVGLLPVRPQPVAPATDPTPSYPSPVPSERLPTDPPSPSTTLPN
                     DTSPGEAGSSGAEDPTGLPTRTAMSRTTTPQSPPSDTAPATVRTSATTSATTDGSGPVP
                     "
     gene            18151..19533
                     /locus_tag="I6J40_RS19585"
                     /old_locus_tag="I6J40_19575"
     CDS             18151..19533
                     /GO_function="GO:0000009 - alpha-1,6-mannosyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004376 - glycolipid mannosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006506 - GPI anchor biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958797.1"
                     /locus_tag="I6J40_RS19585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19575"
                     /product="mannosyltransferase family protein"
                     /protein_id="WP_239589821.1"
                     /transl_table=11
                     /translation="MSPGPRPPSPAPRSPSPGPLPPATRPSIPAPRTSVRSEPRGPLAP
                     PDGRGPAVPPGGQGHDTGPGPGGGIRRTAARLDSADRTVLGLYLLTRISLAITAHLARW
                     LFPGQSGAREAAPVLAPFQHWDANHYLHIARDGYFPAGEGPWTSGWDSREAFFPGYPLT
                     LRAVHAVVPDWTAAGLLISFAAGAVAVVALARIARAYLPDSAAGSRTVLFLLLSPCAVF
                     LAVGYTEALFLAFALPAWLAATHHRWALAAVLTTLGTTVRISGLFLAAAIGLLFILATA
                     KGKSAAPGREGRRSWWAAGWTLLPALPPAAYSWYLHAHTGDWMAWKHAQERGWYRTFHT
                     PWEAWGNTWTGAFGHTQSTGYALMFQAELAAMLVGLALVAVLLYRRRWPEAVYVILSLW
                     ALGTSYWYTSVPRATLLWWPLWIGLAALSLRRPWFRTVYLCVAAPVTTLVALAFLTGRW
                     AG"
     gene            complement(19683..21869)
                     /locus_tag="I6J40_RS19590"
                     /old_locus_tag="I6J40_19580"
     CDS             complement(19683..21869)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958791.1"
                     /locus_tag="I6J40_RS19590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19580"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_030199737.1"
                     /transl_table=11
                     /translation="MSGPTEGRAEDNGRVYQSQGDQHITEHHHHGSPAEPSGATPDSVR
                     RPAVGRAPVVLRDRLELMTRLRTALAEDGGEQVFVLHGLGGCGKTAVASEVFRTATTEG
                     GRVGLWVNAPDLASLRAGMLAVAADRGASEGELTAARAGLRAAADLVWDRLDRSAQPWL
                     LVIDNADDPAILREGNWLRTSPAGITLVTTRQVASHWWPGATLHHVGVLPREDAAQVLC
                     DLAPDRGTPEEAAKIADRLGRLPLALTLAGGYLAHQVISPWSLAEYGRALQQGDDIDPI
                     ALLDQGAAYSGADASRHLASSTWELSLASLRAHGLPESTALVRLLGCWSHDPLPLALLA
                     GPGIDPVVPRARVESALRGLIDHSLTRLVPGPPRCLRTHGVLLESIARGTPADQRDVLV
                     ATAADLLLPVLPEVSRPWKRDDPALAPYVPHALALLRRATQWPGVGRATVARVLECTLR
                     LAVALHRAGDYASALSVAQEAVACGTTALGANHPAVIAVRQRTGRSLYRLGRYEEAETV
                     HRLALADCTAAFGERAVETLESCAGLSPVLAWVLDQKDAAAALVRRAVEGRTAALGAAH
                     PSTLVARTCLLEFTAGPETDPAVGTALLADCHRVVGPGHPIALDAELNLGFALITAGRQ
                     PAALPHVRSAVAGCEHAYGLDHPKTLAARSLHSRALGEVGRIDEAVEEAERITDARARV
                     LGAEHPWTRWSRERLGEWRRAREASSAGGEEAEA"
     gene            complement(21866..22264)
                     /locus_tag="I6J40_RS19595"
                     /old_locus_tag="I6J40_19585"
     CDS             complement(21866..22264)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976032.1"
                     /locus_tag="I6J40_RS19595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_19585"
                     /product="hypothetical protein"
                     /protein_id="WP_030199740.1"
                     /transl_table=11
                     /translation="MDPELTTLAQSAGVTLVGLMATDAWERARDGVVALWQRARPERAD
                     AVAAELTHTRYDLTADSSVGEELAAEWQGRIRRLLTERPEVAADLRALLDELAPGERTV
                     APTVAQRATASGSARVYQAGRDQHITER"
     misc_feature    complement(22327..22340)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.58"
                     /tool="antismash"
ORIGIN
        1 accccggccg gccgcgaggg gctcgaagcc gtgctcgccc ggcccgaccg tgcggtcgtc
       61 gccctcgact tcgacggcac gctcgccgac atcgtcccgg atcccgaaca ggcgcgcgcc
      121 caccccggca ccgtcgaggc gctcgccgcc ctcgcgccga aagtcgctgc cgtcgccgtg
      181 atcaccggcc gtccggcgga cgtcgcggtg cggttcggcg gcttcgcggg cgtccccggc
      241 ctggagcacc tcgtcgtcct cgggcactac ggcgccgagc gctgggacgc cgtgaccgga
      301 gccgtccacg ccccggcccc gcacccgggc gtcaccgccg tacgtgccga actcccatcg
      361 ctgctcgaaa agtcgggcgt cgggggcggc gcctggatcg aggagaaggg gcaggccgtc
      421 gcggtccaca cccggcgcgc cgacgacccg caggcggcct tcgaggcact gcgcgcaccg
      481 ctcggagagt tggccgcacg gcacgggctg atcgtcgaac cgggccgcct ggtcctggag
      541 ttgcgcccgc cgggcatgga caagggcgtc gcgctcgccc ggctcgtggc cgaactggac
      601 gcggagtcgg tgatctacgc gggcgacgac ctcggggacc tggccgcgtt cgccgccgtg
      661 gagaagctgc ggaccggcgg cgcggacggc atccccggcc tcctggtgtg cagcggcagc
      721 accgaggtac ccgaactcgc cgcccgcgcc gacctgtcgg tgccgggccc ggcctcggtg
      781 gtggagttcc tggcggccct ggcggagcgg ctgtagggct gcggagccgt agggcgtgtc
      841 cggcccgtgc gaaggcgcgc agggcggcat gcgaccgccc cggcccacgc gaaggccgga
      901 agggcggccg tgaaccggag cgccccacgt gcgaacgggg ggggcggccc gaaaccgggc
      961 cgcccctccc gcctccgcgt tcgggcccct accggggcag ctcgtcctgt cgtagggcct
     1021 ccagctgctc caggaaccac gcctggggcg gcagcgccgt cgccgcctcc gccaggcgct
     1081 tcgtgcggcc ggaccgctcg tcgccgctca tcgtcagcgc ctcgtgcagc gcgtccgccg
     1141 tgcccgtcac gtcgtacggg ttcaccacga tcgcgtcctc gcccagctcc tcgtacgccc
     1201 ccgcctcccg ggacagcacc agcgcgcagc cctggtccga gacgaccggg acctccttgg
     1261 cgaccaggtt catgccgtcg cggatcgggt tgaccagagc cacgtccgcc agccggtacg
     1321 cggccaggga gcgggcgaag tcgtccttga cgtgcagcac gaccggggtc caactctccg
     1381 tgccgtactg cccgttgatt tccgtcgcca gggactgcac cgccgccgtg tagtcccggt
     1441 agacggcgag gtcctggcgg gaggggtagg cgaaggcgat gtgcacgacg cgttcgcgcc
     1501 actccgggcg ggcctccagc agggcccggt acgcgtgcag gccgcgcacg atgttcttcg
     1561 acagctcggt gcggtccacc cggacgatgg tcttccggcc ctcgcccacc tgctcccgca
     1621 gcgctgccat ccgctcgtcc acgtccggct cgtgcgcgcg ctcgcgcagg aagtccgcgt
     1681 cggccccgag cccgtgcacc ccgatccggg tccggcccgt gccgccgagg atctccgtac
     1741 agcagccgat gaacgcgtcc gcccagcggc gggtcaggaa cgcggcccgg tccgcgccga
     1801 ggatgccgtg cagcaactgc tccgcgatgt cgtcgggcag cagccggaag tagtccacgg
     1861 gcgcccacgg ggtgtgcgag aagtggccga tccgcaggtc cgggcgcagc tcgcgcagca
     1921 tccccgggac cagggccagg tggtagtcct ggacgaggac cgaggccccc ggctccgcct
     1981 cctcggccag cgctcgggcg aaggcgcggt tgtacgtctc gtacgcggcc cactgccggc
     2041 ggaactccgc gtcgaagacc ggctcgacgg gcgtctggta gagcatgtgg tggacgaacc
     2101 acagcaccga gttcgcgatg ccgttgtagg cgtcggcgtg cacctcggcg tcgatgtcca
     2161 gcatccgcac acccggttcc ccgacccccc ggcgcaccgc ctcgcggtcg ccgtcgccga
     2221 gggccgcgca gacccacagc ttgtcgtcga cggcgctcag cccggagacg agaccgccgc
     2281 cgccgcgctt ggcgtcgagc gtcccgtcct cgccgagcgt gtacgagacg gggccgcggt
     2341 tggaggcgac gaggacctgg gaggcggggg acgcggagga cgtcgtggag ggcgtgtgct
     2401 cggagaccat gtaccggaac ctagcccgcg agtccggccc ccaaacgccc cgccgctccc
     2461 cgcggccacc gcctcacgcc cccggcacga cgggcgagca caccgccccc gccgcggcca
     2521 ccgcctcacg ccgcccggcg cgccgcgtac tccgcgatct cccgcatcgg cggcctctcc
     2581 tcggtgtcga ccgcgtacgt gcggggaacg aagccgtcct cgccgcgctc gaactgggtc
     2641 agcgccggcc gcaccagatg gccccgggag agcctgagct gcgccgtccg gtagatcgcc
     2701 gccgccatcc ggcccagcgc ctgcccgtcc tggtgccggt ggacgcgtac gcccacgtcg
     2761 acctggccca gcgcgtccag gcccaccgtg tgcagcgcgt ccaccagcag ccccagctcc
     2821 actccgtaac cgaccgggaa cggcagccgc tccagcaggg agcgccgcac cgcgtactcg
     2881 ccgcccagcg gctgcacgaa cccggccagt tgaggccagt gcagattgag cagcgggcgt
     2941 gccaccagtt cagtgacgcg accgccctga cctgcggcgt cgccgagcgg gcggtcgtac
     3001 atcgccttga cgaactggac ggcggggtcg gtcagcagcg ggccgaccgt ccccgagacg
     3061 aagtccgccg agaagtccct gaggtccgcg tccacgaagc agacgatctc gccgctggtc
     3121 accagcagtg accgccacag cacctcgccc ttcccgggca gcgccgggat ccggggcagg
     3181 atcgcgtccc ggtggaccac ccgcgcgccc gccgcccgcg ccacggccgc ggtggcgtcg
     3241 gtggagccgg agtcgatcac cacgagctcg tcgacgagcc ggacccgctc catcagctcc
     3301 cggcggatcg tcgccacgat cgccccgacc gtggcctcct cgttcagcgc gggcagcacc
     3361 acgctcacgg tcgtacggcc cgggtcggcg gcccgggcct cggtgagccg gttcagcggg
     3421 cggtcggcgg acgaccagga acgcccggtc agccagcgtc ccacctcttc gagcacggtc
     3481 ggcactcctc gtatgtgatc catctcgcgg ttcggacgtc tatctcaacg gtccggtgct
     3541 tcggttacag tcttgaacaa cgcgtatcgc cgtcgcatgt cggggtcgga gcgcggataa
     3601 acgcctggat cgaagatcca gcgccataga gctcatccag agggactgag ggaacggccc
     3661 gttgaagtcc cggcaaccct cctgccgacc gcgaggtcac ggtggggaag gtgccaattc
     3721 cgtcttgcgg cgaaatgcgt cgcgaggaag atgaggagaa agggacctcc gccatcatgg
     3781 ctgttcagac tgttgcaggt accgcggaca ccaccgctgc cgccacctcg aacgtcgatc
     3841 tcggccccgc cgcggcgctc tcctgccgcg agtgcggcga gcgtttcgag ctcggccccc
     3901 tcttcgcctg cgcctcctgt ttcggaccgc tggaagtggc gtacgagctg cccaccggcg
     3961 cccccgagga gctgcgcaag cgcatcgagg ccggaccgga caacatctgg cgctacgccc
     4021 cgctgctgcc cgtccccgcc gacgtggccg agaagcccaa cctcaacccc ggcttcacca
     4081 agctcgtcaa ggccgacaac ctcgcccgcg agctgggcgt caccggcggc ctgtacgtga
     4141 aggacgactc cggcaacccg acgcactcct tcaaggaccg cgtcgtcgcg atcgccgtcg
     4201 aggccgcccg cgccttcggc ttcaccaccc tctcctgctc ctccacgggc aacctggccg
     4261 gcgccgtcgg cgcggccgcc gcccgcgccg gactgcgctc ctgcgtgttc atcccgcacg
     4321 acctggagca gggcaaggtc gtcatggccg cggtgtacgg cggtgaactg gtcggcatcg
     4381 agggcaacta cgacgacgtc aaccgcttct gctccgagct catcggcgac ccgctcggcg
     4441 agggctgggg cttcgtcaac gtcaacctcc gcccgtacta cggcgagggt tccaagacgc
     4501 tggcgtacga gatctgcgag cagctcggct ggcggctgcc cgaccagatc gtcatcccga
     4561 tcgcgtccgg ctcccagctc accaagatcg acaaggggtt ccaggagctg atcaagctcg
     4621 gtctcgtcga ggaccggccg tacaagatct tcggcgcgca ggccgagggc tgctccccgg
     4681 tctccgccgc cttcaaggcc ggccacgacg tcgtacgccc ccagaagccg aacaccatcg
     4741 ccaagtcgct ggccatcggc aacccggcgg acggcccgta cgtcctggac atcgcccggc
     4801 gcaccggcgg cgcggtggag gacgtcaccg acgagcaggt cgtcgacgcg atcaagctgc
     4861 tcgcccgcac cgagggcatc ttcggcgaga cggcgggcgg ggtgaccgtc ggcgtgacga
     4921 agaagctggt cgaggccggc gtgatcgacc cgacgctcac caccgtcgtc ctgaacaccg
     4981 gcgacggcct caagacgctc gacgcggtct ccgccacctc gcaggccacg gcgaccatca
     5041 agccgagcct ggacgcgttc cgcgccgcgg gcctcgcctc cgcctgacca ccccgaccgc
     5101 agcagccaga aaggcgaccg tcatgagcgt caaggtccgc atccccacca tcctccgcac
     5161 ctacacgggc ggccaggccg aggtcacggc ggagggcgcg aagctctccg aggtcatcga
     5221 gtccctggag aaggaccacc cgggcatcgc ggcccgcgtc ctggacgacc agggcaagct
     5281 gcgccgcttc gtcaacgtgt acgtcaacga cgacgacgtg cgcttcgagg gcggcctcga
     5341 cgctgccacc ccggacggcg cgggcgtctc gatcatcccc gcggtcgccg gcggctgctg
     5401 agccgcgcgg gggccggtcc gcccggggtc cgggtcgtag ggacgggccc cccgggccgg
     5461 acggattgaa cgcacggccc ccgggctgga cgggacgggc gggccggatc gtatgggccc
     5521 cgtccgtgct gatcccgtcg gaacggccgc atcggcccct tccgatctga tcctttcggg
     5581 tctgctccct ttcggggtca ttgagccccg tgtggccgca gtgccttcgt gtgacaccgg
     5641 ttgccccttc cgctccataa gcggaggggg caattctgca tggttgagcg cggtacagtt
     5701 ggggaagccc cgtccgctgc tcgtgccgcc cgcatatgag aatgcgcccg gccccgataa
     5761 gaagcagcca aagtacgtga acctcttgcg gcataagtgc gctttgcccg gcccgacttg
     5821 cccgtaaatc tcggaaaccc gcatattcgc gtgttccggc gcgcccatat ttctcgtccg
     5881 attgacctgt tgcagagggc agttggacgg atacattcgg ccgcggtcga cgcgctgcgg
     5941 cgccgcgcac cctctcctgt cggagggtgg gtcgcgaccc gggcccgcga agtgcggtcc
     6001 cgtgcaagtg ccagtaatag gggagttggc atggctcagg gcaccgtcaa gtggttcaac
     6061 gcggagaagg ggtacggctt catcgcggtc gacggtggtg cggatgtttt cgtccactac
     6121 agcgcgatcc agatggacgg gtaccgcacc ctcgaagagg gtcagcgagt tgaattcgag
     6181 atctcgcagg gccagaaggg gccccaggcc gacatggtca agctcgccgt cggctgagct
     6241 cggcacggtc gtacgacgac accgcgcacg cacgtagggc ccgacccctg gaacgctcca
     6301 gcagggatcg ggccctccgc gcgtcccggg acgtccaggg gcctccgcgc gtcccgggac
     6361 gttccgggcc ctccatgcgt gccggggcgg agcctcgggt cgcgcggttg acggtctccc
     6421 ggtggcctcg gggtcgcgcg gccggcggtc tcccggtggc ctcggggcgc acgcccggcg
     6481 gtctccccgc ggcgccgggt cagcgtggtc ggcagcggcc ccgcgccgcc ccacccgtaa
     6541 ctgcgcccgc gccgcccgcc ccgtaaccgc acccccgccg cccctgtgcg tgacctgcga
     6601 cgcctccgta cgcgggcctg cgacgccttc gtcccggacc gcccggcggg ccccgaccac
     6661 atggcgggct cttgccgaag gcgcttgcac tctcgggggt cgagtgctaa tcattggcgt
     6721 tagcactctc caggtgagag tgacagaact tggaccgggc cggtgaggcc cgcaggcgcg
     6781 gtggggcaag gaaccaccga gtcgcaggcc gtccgtcgcg ggcgcctctc ggtccggagc
     6841 aatccacccc tgtccgggag gaccacttca catggccaag atcatcgcgt tcgacgagga
     6901 ggcacggcgc ggtctcgagc gcgggatgaa ccagctcgcc gacgccgtca aggtcaccct
     6961 cggccccaag ggccgtaacg tcgtcctcga gaagaagtgg ggcgcgccca cgatcaccaa
     7021 cgatggtgtt tccatcgcca aggagatcga gctcgaggac ccgtacgaga agatcggtgc
     7081 ggagctggtc aaggaggtcg ccaagaagac ggacgacgtc gccggcgacg gtacgaccac
     7141 cgccaccgtt ctcgcccagg ctctcgtccg cgagggtctg cgcaacgtcg ccgcgggcgc
     7201 caacccgatg gccctcaagc gcggtatcga gaaggccgtc gaggccgtct ccgccgctct
     7261 gctggagcag gccaaggacg tggagaccaa ggagcagatc gcctccaccg cctccatctc
     7321 cgccgccgac accgagatcg gcgccaagat cgccgaggcg atggacaagg tcggcaagga
     7381 aggcgtcatc accgtcgagg agtcccagac cttcggtctg gagctggagc tcaccgaggg
     7441 tatgcgcttc gacaagggct acatctcggc gtacttcgcc accgacatgg agcgtatgga
     7501 ggcgtcgctc gacgacccgt acatcctgat cgtcaactcg aagatcggca gcgtcaagga
     7561 cctgatcccg ctgctggaga aggtcatgca gtcgggcaag cccctgctga tcatcgccga
     7621 ggacgtcgag ggcgaggcgc tctccaccct ggtcgtcaac aagatcaagg gcaccttcaa
     7681 gtccgtcgcc gtcaaggctc cgggcttcgg cgaccgccgc aaggccatgc tcgcggacat
     7741 cgccatcctc accggcggca ccgtgatctc cgaggaggtc ggtctcaagc tggagaacgc
     7801 cggcctggac ctgctcggcc gcgcccgcaa ggtcgtcatc accaaggacg agacgacgat
     7861 cgtcgacggc gccggtgaca gcgaccaggt tcagggtcgc gtcaaccaga tccgtgccga
     7921 gatcgagaac tccgactcgg actacgaccg cgagaagctc caggagcgcc tcgcgaagct
     7981 ggccggcggc gtggccgtca tcaaggccgg cgccgccacc gaggtggagc tcaaggagcg
     8041 caagcaccgc atcgaggacg cggtgcgcaa cgccaaggcc gccgtcgagg agggcatcgt
     8101 cgccggtggt ggcgtggctc tgctccaggc ttcggccgtc ttcgagaagc tcgacctcac
     8161 gggcgacgag gcgaccggcg ccaacgccgt gaagctcgcg ctggaggccc cgctcaagca
     8221 gatcgccgtc aacggtggtc tcgagggtgg cgtcgtcgtg gagaaggtcc gcaacctggc
     8281 ggtcggccac ggcctcaacg ccgcgaccgg cgagtacgtc gacatgatcg ccgagggcat
     8341 cctggacccg gcgaaggtca cgcgttccgc cctgcagaac gccgcgtcca tcgccgcgct
     8401 gttcctcacc accgaggccg tcatcgccga caagcccgag aaggccggcg cggccgcccc
     8461 gggtggcatg ccgggcggtg acatggactt ctgatcggcc tgccgatcgc gaagctccgc
     8521 gtacgtccct caggggcggc atctccttca cggaggtgcc gcccctgagg cgttggcggg
     8581 cacgactccg gtgcccggtg cggctcgcgg gcgggggtgg ggccacgcct gcgggggcgg
     8641 tcgaacgggt ccggccgcgg gtacaggacc aggggcaggt ccggatggac ggatacgggg
     8701 gcggcgaggc atggacacgg gtgcgggcgg ggcgggccgt acgggcggcg accctgtggg
     8761 cggcgagggg cgtacgagag gcggcgcgag gccggcgggc cggggcggtg gcgcgggcgg
     8821 gcggcggctc gcggggctct cgctcctcct cggcggaggc gcgctcgtcg tcctggggct
     8881 gatggtcgtg gtgaccggta cggggctctc cggcgccctc gggatgcggg tcgagacctt
     8941 cgggcggatc gactgccgcg acacccgcac gcagaagggg cagaccgtcc ggcactgctt
     9001 cggtgagagc ccggcccagc agcgggcgaa cagggccgag ctcaagcagg tggacctgga
     9061 gatgctgcgc gcccatctgg acggcgtgcc ccgggccccg gagctccaac ggacccggat
     9121 cctcttcacg gaccacgacg ggcggacgga cccggacacc gtcaccgcga cccaggtgtt
     9181 cgacggcggg cggtggtacg cccactcctc gacgctcgtc ggctacggca tgatcccgct
     9241 gctgctgggc gccggcacgg cggcctgggg cggctaccgg ctgcgtgggc ggcgagaagg
     9301 cgcgggtgcg gggtagtcgg gcggtggccg ggagcggtcc gcgtggccga atggtgtctt
     9361 gcagcggtct tcccggtgcg gcagcacgcg tatcggcggt ttcgccgaag gcgctggcgc
     9421 caccgtggcc gctgaggtag tgcgcctccg ggacggaggc gggcccacgg gggctggttc
     9481 ggcggatatg cgcgcggcac ctccctctcc tggcagctca ccgcccggtt cgatcatcct
     9541 ggcccgttat tggtccagtc cacttgagtg ctgggcgtgc tcggtgtgcg actgcacatg
     9601 ccgaccggtc ggttgcgcgc gtcgtcccgg agtctcgccc tccgctcttc gtcgctcatg
     9661 cgatccggcc aacttcatac ggtgagccgg aatcgcgcgt accggtgctg ctgagggaca
     9721 tgatggctct ggtgttcacg tggtgaacac ctgtcgcatg aataacgtca gttatgcaga
     9781 ggcaagttgc gcataacggt ctccaaccgc tcagaaggga aggtgtcatg aagcagcaga
     9841 agaaggctta cgtgaagccg tcgctgttca agcagggcga cttttcgaag aagacggccg
     9901 gttacttcta cggctcgtac aaggagtact gggtccgccg catcatctga tccggccccc
     9961 ggattcctgt gcgacgtctg agaacttccg gaaggtgaac atgcccggcc atctgcgtga
    10021 ctacttcgtc gttctgccgg acagcgcggc gggtgcggcg gtggccgggc ggcttcccgt
    10081 gcgggagtcg accgggcggt ccgccgccca ggagtcgacc gggccggccg cggcgggggg
    10141 cgacgggctg accgtcctcc atccgtccgg ccggccctgg gtcgtcgccc gcacggcctt
    10201 ccgcgaggtg agccacctcc gccggggcga cgacgccctc gtcctcatcg gccccgaccg
    10261 ggtccccgag tccgtgctcg ccggcctgct ggagggcgcc cgcgaccgcg ccggtctgga
    10321 gcgccgcctc gcccggcggc ccggcctcca ccacgtcatc gcccggctct ccgggcagac
    10381 ctggatcaga ggcaccgcct ccggcctgcg ccggatctac cacgcccggc atccggaggc
    10441 cggaaccatc gcctccgacc gccccgccgt cctcgcgcgg ctgatcgacg cacccctgga
    10501 cgacggcgcg ctcgccctgc gcatgctcga cttcctgccg caccccctga gccgccgcgt
    10561 cgtgtggcgc ggggtgcacg agaccggcgc cgggtacggc ctggccctgc ccgtcgcagc
    10621 accgggtacg gccgccgtcc ccggccccgc ggagtaccgc tggtgggagc cgccggcccc
    10681 cgaactcccg ctggccgaag gggcgcgggc gctcggcgag gccatcgccg cctccgtacg
    10741 cgcccatgtc ggcggccacg accggatcag ctgcgaactg tccgggggcc tggactccac
    10801 ggccctcacc ttcgccgccc gcgcgaccgg cccgcgacgg ctctcgctgc tcaccgtggc
    10861 cgcccgcgac cgctacagcg aggacgagac ctgggcgcgc cgggcggtgg agctggccgg
    10921 gcaggacgat caccccaagc agagcgccca gacccgccac gccgacgagc ccaccgcagt
    10981 cggccggtcc accgcaaccg gtggtcggcc tgccgcagcc ggccggtcca ccgcagccga
    11041 ccggcccgcg gacccaggcc ggccagcggg ccccgagcgg gacgcggatc ccgacctgga
    11101 gcaccgcgtc atcccggcgg acgacgctcc gtacttctac gccgatctgg cctcctgcgc
    11161 cgccgagttg aacgacgagc cgctgccggt cgcccccggc cgggcccgcg ccgaactcct
    11221 cctcggccgc gcccgtgcca ccggctcgcg ctaccacctc accggctacg gcggcgacga
    11281 gctcttcctc gggctgcccc acgcctacca ggacctcttc cacgggaacc cgttcaccgc
    11341 ctggaaccac ctcggaggcc tgcgccacca gctcggctgg ccgctcctgc ccacggtgaa
    11401 ggccctgctg aaccgttcct ccttcccgcg ctggctcgcg ggggccgtca ccgccgaagc
    11461 ccagccggtg gccaggaccc cgctcctctc ctggggcgta cggcagtccc tgcgcccctg
    11521 gttcaccgaa ctcgccaact ctctgatcat tgaggagttc cgggccgccg ccgaacacgc
    11581 cgagccgatc gacccgtggc gcgggcggca cgtcgacatc gacgccgtac ggatgggagc
    11641 ccggcacttc caggcgatgg aggacatcgg cacgacgatc ggactgccgg tcgccgcgcc
    11701 cttctacgac gaccgggtcc tggaggcgac cctcgccgta cgcctcccgg accggatcag
    11761 cccctggcgc tacaagccgc tgctggtcga agcgatgcgc ggggtggtcc cggacgcgct
    11821 gctggcccgt acgacgaagg accacatgtc ctccgacgaa caccagggac tgcgcgaaca
    11881 cggccccgaa ctggccgagt tgtggaccgg ctcccgactc gccgaacgcg gcctggtcga
    11941 cggccgccag ctcctccggc tcgccgccga acccttctcg cccgtcctgg tcgagcactc
    12001 catcagctcc accgtggccg gggagacctg gctccgcacg gccgagaacg cctggccgac
    12061 ggccccgtcc cgatccgaca gcacctcacc cctcacccgt accagcgagg caatcctgtg
    12121 aagctcagaa aaggcatcgc cgtcacgacc accgagtacg gcggcgtgct cctcgacgag
    12181 aacgacggca gctactggca gttgaacgac accagcgtca tcgtcgtcga cacgctcgcc
    12241 gccgggcaca cgcccgaaat cgccgtcgag cggatcgtcg ccgcgttcga cgtcgagcgc
    12301 gccgaggcgg agtccgatgt ggcggagctg acccgccagc tcgtcgaggc gaagatcctg
    12361 cacgcatgac caccgagatg acgatgccgc gccggggcgc gggggcgggc gggatacggc
    12421 tgcgtacggc catcgccgcc gcgttcgtgc tggcccgcct caagccggga cggctgcgcc
    12481 gggtcctgga ccggtgcgcc cggggcgcgc gcccggcctc gtacgcggag accctggagg
    12541 ttttcgaggc ggtggtctcc accagcaggc gctgcgcggg ccgttacggc tgcctgccgc
    12601 gctcggtcgc catcgccctg gcctgccgga tgtccggcgt ctggcccgac tggtgcgcgg
    12661 gggtgcgggc ggcgccgccg ttcgccccgc atgcttgggt acaggcgggg ggccgtacgg
    12721 tcggggagca ggcggaaccg gcggatctgc gtcccttgat gacagtgacg gcagacggag
    12781 gggatccggg tgggcacggc gacggggacg acggcggacg cggagcggaa cgggccgcct
    12841 gagaacggtg gaccgggcgg gcccgccggt ggggcgggcc gttccgcgcc cccggacccg
    12901 cccgagcgcc ccgccccctc tgcgcctccc ggcccgtccg gggccgccag aacgtccggg
    12961 gccgccgacg ccaacagcgc gcccggcccg gccgaggctt ccggctcctc cggcgacccc
    13021 ggctcctccg aggcttccgg ctcctccgag gcccccggcc cgtcacccct gcgcctgctc
    13081 ctctcgcggg tccggccgca ccagggtgtc ctgctccgcg cggggctgct ctcgctcgcc
    13141 ggctccgggg cgggactggc gatgccgttg acggcgaagt acgcggtgga cgcgttcgcg
    13201 gcggaccgct cgcccgccgg cccgctcgtc gcgctgaccg cgctggtgct ggtcggcgcc
    13261 tgtctctccg cgtacggtcg ctacctcatg tcccgtacgg gcgaaggcgt cgtcctccgg
    13321 gcgcgtgacc aactcgtcgc ccgcatcatg cggttgaagg tgccggcggt ggaccggctg
    13381 accccgggcg atctccagtc ccgcgtcacc agcgacacga ccctgctccg tacggtcctc
    13441 tccagcggac tggtcgagtc gttcaacagc gtgctgatgc tgctcggcac gatcggcttc
    13501 atggcgtaca tggacctgac gctgctcggc gtgacgctgg tggtgatcgt cggcatcggg
    13561 gcggtgacgt ccctgctgat gccgcgcatc cagcgggccc agctccgcgc ccaggagtcc
    13621 gtgggcgcga tgggcgcggc cctcgaccgg gtgctccagg cgttccgcac ggtgaaggcg
    13681 agcggtgcgg aggagcggga gacggcggcc gtcgcggcgg cggcccggca cgcgcacgac
    13741 cggggcgtca ccgtcgcgaa gtgggcctcg gtcaccgacg tcacgatgat gatgtcgatc
    13801 cagctcgcgt tcctggcggt gctgggggtg ggcggtgcgc gggtggcctc cggttcgctg
    13861 gagatctccg cgctgatcgc gttcctgctg tacctcttct acctgatggg cccgatcggc
    13921 ggcctggtcg agggctggac gggactgcag agcgggctgg ccgcggtgcg caggatcgac
    13981 gaggtggagt cgctgcccgg cgaaccggag ccggagaccg cacccgtgcc cgtacgggat
    14041 cggggtcccg cgcgcccgct cggcgtcgcc ttccaggacg tggtcttcgg gtacggggac
    14101 gagcgcgccc ccgcccacca gggcgtgacg ttcgacgtgc cggccggcgg gatggtggcg
    14161 ctggtgggcc cgtcgggggc gggcaaatca acggtgttca gcctgctgga acggttctac
    14221 gaccacgacg gcggcacgat ctccgtggcc ggccggaaca tccgggactg gccgctggcc
    14281 gaactgcggg gcgctctggc gtacgtggag caggacgcgc cggtcctggc cgggacgctg
    14341 cgggagaacc tcctcttcgc cgccccggaa gccgacgagg aggcgctggc gtcggcggtc
    14401 gcccgtaccc ggctggacgc cctggtcgcg cggctgcccg aggggctgga cacggcggtc
    14461 ggccaccggg gcgtcaccct ctccggcggc gaacgccagc gcatcgccat cgcccgcgcc
    14521 ctgctgcgcc gcccccgcct gctgctcctc gatgaggtga cctcgcaact ggacgcggtc
    14581 aacgaacagg cgctgcgtga cgtgattctc gaactggccg agcagaccac ggtgttggtc
    14641 atcgcgcacc gcctctccac cgtgcggcac gccgaccgca tcgtggtcct ggaggagggc
    14701 cgggtccgcc gtgcgggcac gcatgaggag ttgctcgcgg aggatgacct gtaccgcgaa
    14761 ctggcgacga cgcaactggc ggcggacgcg cggtgagcgg cgccgggcgg gggcccggtc
    14821 gagagggagg gcggggagtg gacgcggagt tgtcggcccg gttcgccgcg gaggtcgact
    14881 ggtcgaaggt ggtcgacccc tacacgccct ggcagcacgg gccggacctg ctggagcggg
    14941 tctggtcgcc cgacgcgcgg acggccgacg acgcgcacgc ggacctgcac gtcgcgtgct
    15001 gcggcgacgg aagttcggtg ctgcccgcgg cggtcgaggt gctcccgttc ctcgtccggg
    15061 ccgccgggga cccggacgtg cgggtgcgcc cgcagatcct cgacacgctc gccgtactcg
    15121 gccgcgccgg caacgccgcc cggccctccg cgcccggccc gaagcccggc gggtggcggc
    15181 ccaccgcgcc cgccgcgtgg cccgcggcct ggtaccgggc gaccgacgca ctgctgccgg
    15241 ggctcgcgga cggtgacgag gccgtacggg ccggggtggc ggccgtactc gcgcaggcca
    15301 ccgggcgggc ggacgacctc gtggaccgcc tccggtcccg cttcgaggac gagcccgagc
    15361 agccggtcgc cgagcaactc gtgctctcgg tgggcgaact ggccccgcac gccgtgaacc
    15421 ggcgcgcggc ggccgtcgcc tggctccggc agcggatgga cgatgtcggg aagggcgagg
    15481 aaccggacat cgaccaggac gtcgacacgt ggatcgcctg gaccggacag cacggccacg
    15541 acgtccggtt gtccgcggtc gccgcgctgc gccgcgccct ccccgggcgc ccggaccccg
    15601 cgtacgcccg taccaccgtc gacgcgctga tcaggccgtc cccgtacgac gccgcccggt
    15661 tcgggggcca ccgctccctg tacgtcaccc gggccgtcga tgccgacgcg cggctcgacg
    15721 aagaccttcc cgggcgactc gccctcgccc gggagctgct gcgccaggac agcgccgccc
    15781 accacgagag cgggctgcgg atcgcggcgt ccctgatgtc ccggtggcgc tccgccgtac
    15841 cggaactcct gccggacgtg gcggagttcg tggacgcccc ggacgaggtg aaccggtcct
    15901 tcgcgctccg ggtcctcgcc atgtgcggta ccgccgcccg cccctggtcc gaccgcgcgg
    15961 cggcgcacct ctccgaggac gacgaaccgt acgagcccgc gcgccggcac gcggtgtgga
    16021 tgctgagccg ggccggggac gaacgctgcg tggaacccct gatcgacggg ctgtcgtccg
    16081 ggcgggccac ggggttctcc gcgagcccgc cgtacctctc cacctgcgac tgggagaaga
    16141 gcgacctcaa ctacacggaa gcgctgcgcc cgttcgccgt gcgggcggaa gcgctccccg
    16201 tcccgccgcc gacgcggggc ggcgtcccgg ccgcagccga tcgagaccgc cgttcctcca
    16261 tcccgcagga cgccacggaa agggcccgag tccggtggcg ggaggccggc gatccgaacg
    16321 aagtcgtgca cggcctgctg gagttgacgg cgaacagcgc ccggaaggcg tacgcgaccc
    16381 cgggcggcgt gaagcccctg ctcctgctcg ccgagatcgc cgccacacat ccacccgtgg
    16441 ccgacgaggt ggcgggccgg ctggcggcca ccgcgcgggc gcgcgtcgag ggcgactgcc
    16501 gcttcgaggc gatgacgctc ctgcgggccc tgtgggagct gacccgggac ggccaccggg
    16561 tggcccccgc cctggtcgac ctcgtccgga tctgcccgcc cggcgtcgcg ccgcccacga
    16621 tcgtggaagc cgtggaactc ctcgccgagg tcgcggccgc cgacccgccg gccgcgacgg
    16681 ccgtcgcccc gcgggtccgg cgcctgctcg acaccgacga gcgccccgtc cgccacgacc
    16741 agtggcgcgc cgtcctcagc gacgatgcgc tgctcgcggc ggtacgcacg gtggtcgggg
    16801 cggctcaggc agcgggggcg tagcccgtac gggagggggg aggccgtgcg gttcagcagt
    16861 ggccggggcg ggcgccgacg ccaggtgacc gaccggtccg gtcggccgcc ccggcggaga
    16921 ggggccatgc agtccctgtg acgaccgtca ccacgaattc tccgggtgcg tgtcgaccgg
    16981 atgggcggcg gcgggcgtat acccggtgaa gcgaaagacc cgggagcgac atgtgaccgt
    17041 cgaggagttc gaagagttct acgcccaggc ggtcgcgcgg ctcacaggac agctgtacgt
    17101 gatgaccggc gacctccagg aggcgcagga cgtcgtgcag gaagcgttcg tcaaggcgtg
    17161 ggtgcggcgg gggcggctgg agcgtgaggg gcagcccgag gcgtggatcc gtaccgtcgc
    17221 ctggcggctc gcggtgagcc gttggcgctt ccggcggcgc tccgcggacg cgtggggcct
    17281 ggggagcggg cggtcgccgg agcacgtgga gccgccgggg ccggaccacg tggcgctggt
    17341 cgccgcgctc cgggagctgc ccgcccagca gcggcggacg ttgaccctgc actacctgtg
    17401 cgacctcacg gtcgagcaga tcgccgggga gaccgggctt tccaccagca cgatcaagac
    17461 gcatctggtt cgcggcaggg cggcgctcgc gcaccggctg caggaccccc gcatcgagga
    17521 ggcacgtgat gtctgaacgg cgggatccgt tgcggtccct gttccgggag gccggcgagt
    17581 tcgggcagat ccgcgccgaa gcggacgacg cggcgaggat cacccagcgc ggcatgcgcg
    17641 cccagcgccg gcggatggcc gcggtcgcgg tgggcgtctg cctggtcgtg ggcgggggtg
    17701 gcgccgcggc ggtgggcctg ctgccggtac ggccgcaacc cgtcgccccg gccaccgacc
    17761 cgacgcccag ctacccgtcg cccgtcccct ccgagcgcct gccgaccgat ccgccgtcgc
    17821 cgagcaccac gctgccgaac gacacgtcac cgggggaggc ggggagttcg ggggcggagg
    17881 accccaccgg cctgcccacg cggacagcca tgagcaggac cacgacgccg cagtcaccgc
    17941 cgtcggacac ggccccggcc accgtcagga cgtcggccac cacgtccgcg acgacggacg
    18001 gctccggccc ggtgccctga ccccggggcc gggcccccta cgcttctccc gcgccccggc
    18061 ggctaccggg ccatcccgta cacccccgta cgccccccct gcctcggcgc acccgcgagg
    18121 cgcgcccgaa aggtgcctga gttgaccacg ctgtcccccg gaccacgtcc cccgtccccc
    18181 gccccccggt ccccgtcccc cggaccactg ccgcctgcca cccgcccgtc gatccccgcg
    18241 ccccggacct ccgtgcgttc cgaaccgcgc gggcccctcg cgccgccgga cggccgaggc
    18301 cctgccgtac cgcccggggg gcaggggcac gacacgggtc ccgggcccgg gggggggatc
    18361 aggcggacgg cggcgcggct ggactccgcc gaccgcacgg tgctcgggct ctacctcctg
    18421 acccgcatat ccctggcgat cacggcccac ctcgcccgct ggctcttccc cggccagtcc
    18481 ggcgcccggg aggcggcccc ggtcctggcg cccttccagc actgggacgc gaaccactac
    18541 ctccacatag cgcgcgacgg ctacttcccg gcgggcgaag ggccgtggac cagcggctgg
    18601 gacagccggg aggcgttctt ccccggctat cccctcaccc tgcgggccgt gcacgcggtc
    18661 gtcccggact ggacggccgc cggtctgctg atctcgttcg ccgccggggc cgtggcggtc
    18721 gtggcgctgg cccgtatcgc acgggcgtac ctcccggaca gcgcggcggg ctcccgtacg
    18781 gtgctcttcc tcctcctctc gccgtgcgcg gtgttcctgg cggtcggcta cacggaggcg
    18841 ctgttcctcg cgttcgcgct gcccgcgtgg ctggcggcga cgcaccaccg gtgggcgctc
    18901 gccgccgtac tgaccacgct gggaacgacg gtgcggatca gcggcctgtt cctcgcggcg
    18961 gccatcgggc tgctgttcat cctggccacg gccaagggga agtcggcagc acccgggcgg
    19021 gaggggcggc ggagctggtg ggcggcgggc tggacactgc tcccggcgct gcccccggcc
    19081 gcgtacagct ggtacctgca cgcgcacacc ggcgactgga tggcgtggaa gcacgcgcag
    19141 gagcgcggct ggtaccgcac gttccacacg ccctgggagg cttggggaaa cacgtggacc
    19201 ggggcgttcg gccacaccca gtcgaccggc tacgcgctca tgttccaggc ggagttggcg
    19261 gcgatgctgg tggggctcgc gctggtcgcc gtcctgctgt accggcgccg ctggcccgag
    19321 gcggtgtacg tcatcctcag cctgtgggcg ctcggaacct cgtactggta cacctccgtc
    19381 ccccgcgcga cgctgctgtg gtggccgctg tggatcggcc tggcggcgct gagcctgcgc
    19441 cggccgtggt tccggacggt gtacctgtgc gtggcggccc cggtgacgac gctggtcgcc
    19501 ctggcgttcc tgacggggag atgggcgggg tgacctctct ggcgggggcg gggcggcttc
    19561 ttggcggggg ccgggcaggg tgggttctct ggcgggggcc gggcgggctg cgtcggggtg
    19621 ggcggggcga ggcgggtggg cgcggggaag ccggagcggg gccgttccgg tgtcgcgcgg
    19681 ccctacgcct cggcttcctc cccgcccgcg gacgacgcct cccgggcgcg ccgccactcg
    19741 ccgaggcgct cccgtgacca ccgggtccag gggtgttcgg ctcccagcac gcgtgctcgt
    19801 gcgtccgtga tccgttccgc ctcctccacc gcctcgtcga tccggccgac ctcgccgagg
    19861 gcacggctgt gcagggaacg ggcggcgagg gtcttcgggt ggtcgagccc gtaggcgtgt
    19921 tcgcacccgg cgacggcgga ccggacatgc ggcagggccg cgggctgccg acccgcggtg
    19981 atcagggcga aaccgaggtt cagttcggcg tccagggcga tggggtgacc ggggccgacc
    20041 acacggtggc agtccgccag caacgccgta ccgaccgccg gatccgtctc cggaccggcg
    20101 gtgaactcca gcaggcaggt ccgtgccacg agcgtcgacg gatgggcggc gccgagtgcg
    20161 gcggtccggc cctccaccgc tcgccgcacc agagccgccg ccgcgtcctt ctggtcgaga
    20221 acccaggcga gcaccgggga cagccccgca cagctctcca gcgtctcgac ggcccgctcg
    20281 ccgaacgcgg cggtgcagtc ggccagggcg aggcggtgga ccgtctccgc ctcctcgtac
    20341 cggcccaggc ggtagaggga ccgccctgtc cgctggcgga ccgcgatcac cgcggggtgg
    20401 ttcgccccca gcgccgtcgt cccgcaggcc accgcctcct gcgccaccga cagggcggac
    20461 gcgtagtcgc cggcccggtg gagcgcgacg gccagccgca acgtgcactc cagaacgcgt
    20521 gccacggtcg cccgccccac ccccggccac tgcgtcgcac gccgcagcag cgcgagggcg
    20581 tgcggtacgt acggggcgag agccggatca tcgcgcttcc acggccggga cacctccggc
    20641 aggaccggca gaagcaggtc agcggccgtg gccaccagca cgtcacgctg atcggcggga
    20701 gtgccccggg cgatgctctc cagcagtacg ccgtgggtcc gcagacagcg gggcggtccg
    20761 gggaccaggc gggtgagcga gtggtcgatg agcccgcgca gcgccgactc gacccgggcc
    20821 cggggcacca ccgggtcgat gcccggaccc gcaagcagag cgaggggcag cgggtcgtgg
    20881 gaccagcatc cgagcagccg gaccagcgcc gtggattccg gcagcccgtg cgcgcggagg
    20941 gaggccagtg acaactccca ggtgctgctg gcgagatggc gggacgcgtc ggctccgctg
    21001 tacgccgcgc cctggtccag gagcgctatg ggatcgatgt cgtcgccctg ttgcagggcg
    21061 cgtccgtact cggccagact ccacgggctg atcacctgat gggccagata gccgcccgcc
    21121 agggtgaggg ccagggggag ccggcccagc cggtcggcga tcttcgcggc ctcctccggg
    21181 gtgccccggt ccggcgcaag atcgcacagc acctgggccg cgtcctcccg gggcagcaca
    21241 ccgacgtggt gcagggtcgc cccgggccac caatgggagg cgacctgccg ggtggtgacc
    21301 agggtgatgc ccgccggact ggtgcgcagc cagttgcctt cgcgcaggat ggcggggtcg
    21361 tcggcgttgt cgatcaccag cagccacggt tgcgcggacc ggtccagccg atcccatacg
    21421 aggtcggccg ccgccctcaa cccggctcgt gcggcggtga gttcgccctc gctcgcgcca
    21481 cggtcggcgg ccacggcgag catgcccgcc cgcaaggacg ccaggtcggg ggcgttcacc
    21541 cacaggccga cacggccgcc ttcggtcgtc gccgtacgga agacctccga ggcgacggcc
    21601 gtcttgccgc acccgccgag gccgtggagc acgaagacct gctcccctcc gtcctccgcc
    21661 agggcggtgc gcagccgcgt catcagctcc agccggtcgc gcaggacgac cggcgcgcgc
    21721 cccaccgccg gccgcctgac ggagtcgggt gtggcgccgg acggttcggc gggggagccg
    21781 tggtggtggt gctcggtgat gtgctggtcg ccctggctct gatagacgcg gccgttgtcc
    21841 tccgcccgcc cctcggtcgg cccgctcacc gttcggtgat gtgctggtcg cgaccggcct
    21901 ggtagacccg ggcgctcccg gaggcggtgg cacgctgggc cacggtcggc gccaccgtcc
    21961 gctcaccggg ggccagttcg tccagaagcg cccgcaggtc cgccgccacc tcggggcgct
    22021 cggtcagcag ccgccggatg cggccctgcc actcggcggc cagctcctcc ccgacgcttg
    22081 agtcggccgt caagtcgtaa cgggtgtgcg tgagttcggc cgccacggcg tccgcccgtt
    22141 ccggcctggc ccgctgccag agggcgacga ccccgtccct ggcgcgttcc caggcgtcgg
    22201 tcgccatcag gccgacgagg gtcacccccg cgctctgggc gagtgtggtc aactccgggt
    22261 ccatcgcgca cgctcccttt tcatgacgca ctccgcgtac gtgtggcgca cgctgtcctc
    22321 tcctgccgca tggccgtgcg gttgcgggtt cctgccgccg gctcctgccg gttccggctg
    22381 ccgtgggctc ctgctgcggc aggtttctgc tgccggtcgc cgccgtgggt tcctgccgcc
    22441 gcgggcttcc gccgatggtg gacggtcgcc gcgtgagcgg tgggcccgcc tcgccggtga
    22501 acgcccgttc cgtcagtggt cgggcccgtt ccatcgttgg tcgggcccgt tccgtcagtg
    22561 ggcggatgat gccggaagct gggcggacgg tcggcggacg gccggcgggg cgagcggggc
    22621 gatctcccgt tcgaagaacg ccgcgatgct ctctccccgg gcgtacaggt ccttgaactc
    22681 cgcgactatc gcccgaatca gacccgggtc ggtgaacctg cgggcgcccg cgcctttccc
    22741 ctcggcgtcg tagatcaccg tgtacatcac cgaacgtccg agaacgacca cctcgggcag
    22801 cttcgcgtcc cgttccagtt cggcgatttc cccggcgggg ag
//
