LOCUS       NZ_CP070260            22751 bp    DNA     linear   CON 30-MAR-2024
DEFINITION  Streptomyces californicus strain FDAARGOS_1210 chromosome.
ACCESSION   NZ_CP070260
VERSION     NZ_CP070260.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces californicus
  ORGANISM  Streptomyces californicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7919564)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7919564)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T., Yan,Y.
            and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2021) Institute for Genome Sciences, University of
            Maryland School of Medicine, BioPark II, 801 W. Baltimore St., Suite
            619, Baltimore, MD 21201, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 8.0.0, HGAP v. 4
            Genome Coverage                   :: 624.55x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016906265.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 09:02:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,240
            CDSs (total)                      :: 7,147
            Genes (coding)                    :: 7,032
            CDSs (with protein)               :: 7,032
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 115
            CDSs (without protein)            :: 115
            Pseudo Genes (ambiguous residues) :: 0 of 115
            Pseudo Genes (frameshifted)       :: 36 of 115
            Pseudo Genes (incomplete)         :: 97 of 115
            Pseudo Genes (internal stop)      :: 12 of 115
            Pseudo Genes (multiple problems)  :: 27 of 115
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:25:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2542896
            Orig. end                         :: 2565647
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070260.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22751
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="16"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22751
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22751
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12751](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12751)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    323..341
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    complement(545..560)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.37"
                     /tool="antismash"
     misc_feature    complement(579..593)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            672..1112
                     /locus_tag="I6J40_RS10895"
                     /old_locus_tag="I6J40_10885"
     CDS             672..1112
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127370.1"
                     /locus_tag="I6J40_RS10895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10885"
                     /product="hypothetical protein"
                     /protein_id="WP_030119450.1"
                     /transl_table=11
                     /translation="MSLPLTRRIARAALLIAAGAAPVVGAAGAASAAELPQTTDLGGLT
                     SLDGASVGNTLDSTARQGTEAAGQTGGRLVGTALPAAGETLGRSAKVAVPAVQETAGHT
                     AGSAGEAVGGVAEAAGKGLPTDSLTQGGLPTDALPLNGLPIG"
     gene            complement(1225..2319)
                     /locus_tag="I6J40_RS10900"
                     /old_locus_tag="I6J40_10890"
     CDS             complement(1225..2319)
                     /EC_number="2.6.1.17"
                     /EC_number="2.6.1.79"
                     /NRPS_PKS="Domain: Aminotran_1_2 (29-363). E-value:
                     1.2e-45. Score: 148.1. Matches aSDomain:
                     nrpspksdomains_I6J40_RS10900_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984558.1"
                     /locus_tag="I6J40_RS10900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10890"
                     /product="bifunctional succinyldiaminopimelate
                     transaminase/glutamate-prephenate aminotransferase"
                     /protein_id="WP_030119449.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-43, bitscore:
                     148.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVSSRLPVFPWDRLAPYKSTAQAHPDGIVDLSVGTPVDPVPEL
                     IRRALVEAADSPGYPTVWGTEELRDALTGWVERRLGAVGVTHANVLPVVGSKELVAWLP
                     TQLGLGAGDRVAYPRLAYPTYEVGARLCGAEPVVYDDPTELDPAGLKLLWLNSPSNPTG
                     KVLSKEELTRIVAWAREHGVLVFSDECYLELGWDADPVSVLHPDVCGGHYEGVVAVHSL
                     SKRSNLAGYRAAFIAGDAAVLGELLLIRKHGGMMTAAPVQAATVAALGDDAHVSEQRVR
                     YADRRLALRAALEGHGFRIEHSEASLYLWATRDEPCWDTVAYLAERGILVAPGDFYGPA
                     GERFVRVAFTATDERVAAAVKRLS"
     aSDomain        complement(1231..2232)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6J40_RS10900_Aminotran_1_2.1"
                     /evalue="1.20E-45"
                     /label="I6J40_RS10900_Aminotran_1_2.1"
                     /locus_tag="I6J40_RS10900"
                     /protein_end="363"
                     /protein_start="29"
                     /score="148.1"
                     /tool="antismash"
                     /translation="IVDLSVGTPVDPVPELIRRALVEAADSPGYPTVWGTEELRDALTG
                     WVERRLGAVGVTHANVLPVVGSKELVAWLPTQLGLGAGDRVAYPRLAYPTYEVGARLCG
                     AEPVVYDDPTELDPAGLKLLWLNSPSNPTGKVLSKEELTRIVAWAREHGVLVFSDECYL
                     ELGWDADPVSVLHPDVCGGHYEGVVAVHSLSKRSNLAGYRAAFIAGDAAVLGELLLIRK
                     HGGMMTAAPVQAATVAALGDDAHVSEQRVRYADRRLALRAALEGHGFRIEHSEASLYLW
                     ATRDEPCWDTVAYLAERGILVAPGDFYGPAGERFVRVAFTATDERVAAAVKRL"
     gene            complement(2460..2780)
                     /gene="fdxA"
                     /locus_tag="I6J40_RS10905"
                     /old_locus_tag="I6J40_10895"
     CDS             complement(2460..2780)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950253.1"
                     /locus_tag="I6J40_RS10905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10895"
                     /product="ferredoxin"
                     /protein_id="WP_007446848.1"
                     /transl_table=11
                     /translation="MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGA
                     CEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDDLGSPGGASKLGLIERDHAFIAGLPPQ
                     NQ"
     gene            2898..3899
                     /locus_tag="I6J40_RS10910"
                     /old_locus_tag="I6J40_10900"
     CDS             2898..3899
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035967.1"
                     /locus_tag="I6J40_RS10910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10900"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_030198452.1"
                     /transl_table=11
                     /translation="MEFTIGGRLDVRITPADVGKRVSVRCRTESGGAGAEFTDTVGVLT
                     SWDRDVLSITRKSGESVHIVESSLVAGKTVPPAPARRRGPAASFEELAAVTARAWQPVE
                     SEPLGDWRLRAAGGFTRRANSALPLGDPGLPVGEALDRVRAWYAERDLPPYVQTATGAA
                     GTQELLCAELERHGWRREVTAQVRIAALAPVGDGAADVAAVRLTRAPDAAWLARYQRFS
                     TPGPHVLRVLESGPSVWFATVAGDGGAPDAIGRCVVDGRWAGFMAVEVAPERRRRGLAT
                     TVMTALARRALDEGASAAWLQVEEENEGARALYDGMGFALHHSYHHYRPSPA"
     gene            3993..4874
                     /locus_tag="I6J40_RS10915"
                     /old_locus_tag="I6J40_10905"
     CDS             3993..4874
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956285.1"
                     /locus_tag="I6J40_RS10915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10905"
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_030198450.1"
                     /transl_table=11
                     /translation="MSGLDSGAAERRRQFAEEARSERPDLALLCLLLGAEAGPVGPAEV
                     RPVVPGETDPDPYGIDAAQIELDRLAGLLPYGPRSPAGWASALAELLGGRCGFGGSAAD
                     YQRLDSSCLQQVLRRRRGLPILLSVVWIEVARRAGAPVYGVALPGHFVVGFGDPDHLVL
                     ADPFAGGAPLTGADAELLVTSKTGAPPDPSMTRPARPLEIVLRVLNNIRAWAATRPERT
                     DVALWAVELSLLLPSHPARLRYEHAELLVQRGEFLRGAAEMEEYADVMAGIEPTAAENI
                     RRKARAARALLN"
     misc_feature    complement(4999..5014)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.41"
                     /tool="antismash"
     gene            5165..5770
                     /locus_tag="I6J40_RS10920"
                     /old_locus_tag="I6J40_10910"
     CDS             5165..5770
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127364.1"
                     /locus_tag="I6J40_RS10920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10910"
                     /product="response regulator transcription factor"
                     /protein_id="WP_030119444.1"
                     /transl_table=11
                     /translation="MTTVLLVHTVPLWRASLASLLCAGPDIEVRTAEHGAIRDALGGPA
                     PDVLLTDLDCPGALDVLDEVKTVTAPHGGPYPLAVLTRSDRPRGLRRAYEAGALGYIDK
                     YRPVDDLSEVMHKLADGGRHIDESLAFSLLQVADMPLSPRELSVLSLAEGGDTVAGIAA
                     RLHLTPGTVRNYLAAAIRKSGARNRLDAIRRAKEAGWI"
     misc_feature    5585..5587
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5739..7703)
                     /locus_tag="I6J40_RS10925"
                     /old_locus_tag="I6J40_10915"
     CDS             complement(5739..7703)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446855.1"
                     /locus_tag="I6J40_RS10925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10915"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_205041598.1"
                     /transl_table=11
                     /translation="MKANGPTAPRPRRDTALRRVAREARPFLRARTGAVLRLAGWSLLE
                     FAQTFLSGYGVARALDDGFLASRPATGLCWLAVAAVAVLPSVLAARGVFGRLADLVEPL
                     RDGLVRRAVSRALGGALGRSGDVSTRSLSQVTHQSEIARDGWAGLVLTLRSFAFTAAGA
                     VTGLLALAPALLLIVLPPLAVGAALFLATLPPMAARQRAYLAADEAYAAHAGELAASVR
                     DIAAAGTAGRTVAESGALAEAQLAASRSLARWSAVRVLALAVCGRFPPLLLLLAAPWLL
                     RNGLTAGALVGALTYLTQALAPAVQALMTMLGTAGGRLVVVLDRFTNAPPPPEDDPPQA
                     VRDSAPPPADQTAHPAVPAPAPSARRAPAPVAELHEVTFAYGPRAQPVLDRLSLTIAPG
                     EHLAVVGPSGSGKSTLAAVLAGVEPPTGGAVRWRGRPVRAADATSVRVLLPQHAYVFSG
                     SLRDNLRYLSPDARDREIADAAEAIGLEPLLSRLGSLDADVVPDRLSQGERQLVALGRA
                     YLAAPPLLILDEATSRLDPAAETRAELACAALPGALVVVAHRLSSARRAGRTLVMDGPR
                     TRCGTPAQLLRSSALYRDLAGLWEPEDADARGGGLVPDAQDAVAVAGRLGTVGTGQDAS
                     IGSGDEERGVRSSPPPSPV"
     gene            complement(7700..9715)
                     /locus_tag="I6J40_RS10930"
                     /old_locus_tag="I6J40_10920"
     CDS             complement(7700..9715)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379164.1"
                     /locus_tag="I6J40_RS10930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10920"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_239589690.1"
                     /transl_table=11
                     /translation="MPLHLRPGPASGVRRLSRRHPAALTWLFLCSTGGALAALALPAAL
                     GHTVDRLVSGGPVPWSGLLLCTALTLAETGFDAAAAVTGTTTTARLTASLRTRTAARVL
                     TAEPRRALALPTGDLTARLTARTADAAAAPATAAGAVAGVLLPLGALVGLLLIDVWTAA
                     ALLVGAPLLVVLLRAFTRGTADAGADYQRAQSLIAHRLTEALEGADTIRAARTAAREHR
                     RVLEPLTALAEHGRRTWEVYGRAVGRSGLLLPLLMLLVLAVAGLRLGAGAIGVGDLVAA
                     SRYASLAVGIGSLTGALGALARSRAAATALEPLLALAPLPHRGLGPVPDAPGELELRDV
                     GVEQDGVPLLTGVHLTVPGGTSLAVVGRSGSGKSQLAAVAGRLLDPDTGHVLLDGVPLD
                     GMEPARLRREVAYAFARPALPGTTVEDTIAHGPWTAAPDAVREAARAARADGFVALLPY
                     GYATPLADAPLSGGERQRLGLARAFAHPGRLLILDDALSSLDTVTEHHVRRALDARAGR
                     CTRIIVAHRLSSAARADRVAWLEDGRLRATGRHDELWADPEYRAVFRDEPADATRARAE
                     TETAHEPTGPHPLHQPTGPDTPRERTAPDATQARADAKASREPTGPDTPRERTAPDATR
                     ERADAKASHEPTGPHPLHQPTGPNTPHQPTGAEAAR"
     gene            complement(9843..9974)
                     /locus_tag="I6J40_RS10935"
                     /old_locus_tag="I6J40_10925"
     CDS             complement(9843..9974)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="I6J40_RS10935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10925"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_030112254.1"
                     /transl_table=11
                     /translation="MALLDLQAMDTPAEDSFGELATGSQVSVLVCEYSSLSVVLCTP"
     CDS_motif       complement(9909..9974)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMDTPAEDSFGELAT"
                     /locus_tag="I6J40_RS10935_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9843..9908)
                     /prepeptide="core"
                     /locus_tag="I6J40_RS10935_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="31.80"
                     /molecular_weight="2062.4"
                     /monoisotopic_mass="2061.1"
                     /core_sequence="GSQVSVLVCEYSSLSVVLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMDTPAEDSFGELAT"
                     /leader_location="[9908:9974](-)"
                     /alternative_weights="2080.4"
                     /alternative_weights="2098.4"
                     /alternative_weights="2116.4"
                     /alternative_weights="2134.5"
     gene            complement(10001..12751)
                     /gene="lanKC"
                     /locus_tag="I6J40_RS10940"
                     /old_locus_tag="I6J40_10930"
     CDS             complement(10001..12751)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072047.1"
                     /locus_tag="I6J40_RS10940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10930"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_030195382.1"
                     /sec_met_domain="micKC (E-value: 9.9e-223, bitscore: 740.3,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.8e-12, bitscore: 44.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2e-05, bitscore: 22.2,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYAAYCQADRRFYDAPHRALQPAGGAGGEEHAFYPAVRGAAP
                     QGWTRSRRGDWLSYSPDGLRLPPQGWKLHISAALDNADSVLERVVAHCLAHRLAFKCVP
                     NPGLLALRNAKYADRAGSGKFITVYPPSDEAFPEVCTALMELLDGEHGPYILSDLRCGN
                     GPVHTRYGAFAARFCSGPDGRPVPAVADPRGRLVPDDRGPAFRIPSWVTPPGFLAPHLE
                     ARAAVGLGDLPYTVEKALHFSNGGGVYLGRDTRTGEQVVLKEARPYAGLAADGADAVAR
                     LDRERTALEHLAGLECVPEVKDAFEVGDHHFLVLQYMPGATLNTVFARRFPLARRHPSP
                     ELLAAHAAWAEEVHGQVERAVEAVHARGIVISDLHMSNVMVDEESGRIALLDFEAAFPA
                     ADRRRQIVANPAFVAPADRRGTDIDRYALACLRLALYLPLTTLFGIDRTKAAGLARDIA
                     RVFPVTEEALRPAVAEILRGTGEADATAATDAPPHAAVPGPRTSDASTAPRTPDAATAA
                     PGPYADAAGPDLREWPRAREAMAAAIAASCTPERDDRCFPGDIAQFATATGGQSFAYGA
                     AGVLYALHETGAPPCPAAEDWLLRHAKAPASGSPLGFYDGLTGIAWTLHRLGRTAEAAD
                     LLRIVLDQPLEGLAPGLHNGYAGIGLALDDLARTASGPDAPALSAAAARCTAFAVRALT
                     EGPPSPRTGLLHGASGVALLLIRRYENTGDTALLDLAAAALHRDLERCRAGDDGELLVV
                     EGKRLMPYLGSGSAGIAAVIDAYLAQRPDPALEEAGRALLPAACSAFYVQPGLFRGSAG
                     LLAHLAVTPLAEPADRLRAIDRHLDLLASHALTDGGGLAFPGEQLMRLSMDLATGTAGA
                     LLALGAAHGAPIGLPFLPAAPAAHPAAPAAPQTGPSRGRGNTTVQ"
     misc_feature    complement(12785..12800)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.9"
                     /tool="antismash"
     misc_feature    12788..12801
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 11.94"
                     /tool="antismash"
     misc_feature    complement(12790..12810)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.6"
                     /tool="antismash"
     misc_feature    12839..12850
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            complement(12971..13951)
                     /locus_tag="I6J40_RS10945"
                     /old_locus_tag="I6J40_10935"
     CDS             complement(12971..13951)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611151.1"
                     /locus_tag="I6J40_RS10945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10935"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_030195380.1"
                     /transl_table=11
                     /translation="MGWWQISADTLAGSRFVVSPLAEAVASLLLLERAAAAHPGERAWL
                     AEHLPAYRRRAAEDPVSALVIRSALAPRWTADFLGAAPVPAPPGRPAPAFAEELARMRA
                     TPPDQARADLAVTLGGGPLPAALDRDDLADRAADAVAWVWTHTVLPDWPRRRRVLEADV
                     VARTAHLGRGGWAEALNGMRPGIRWLGESRLQINAYDNPPRELGRAELLFVPVTPNQCW
                     VGWDIPRRYALVYPCSGALTDAGRGPVPTALGALLGAARAAVLVLLASPLSTTQLVALT
                     GQGLGSVGRHLRVLRDAGLVRRRRAGRSVLYVRTEAGDVLVRSAS"
     misc_feature    14139..14157
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.29"
                     /tool="antismash"
     gene            14146..15402
                     /locus_tag="I6J40_RS10950"
                     /old_locus_tag="I6J40_10940"
     CDS             14146..15402
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956279.1"
                     /locus_tag="I6J40_RS10950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10940"
                     /product="MFS transporter"
                     /protein_id="WP_030195378.1"
                     /transl_table=11
                     /translation="MRTYRELFRTPEFTPFFTAVSVQTAAHTATGLALGTLVYTRTGSP
                     LLSALAMFGPSLAQAAGALTLLSAADRLPPRATLTALALLSAVAACVQAVPGLPLWGAF
                     AVLLVVGAAGSAGGGVRYGLLNEIVPREGFLIGRSVLNMTGGAMQICGFAVGGALVAVV
                     SARGTLLVGAALYVVAAAVTRFGLSARPPRAPGRPSVRETRRTNALLWSSVPRRYVFLA
                     LWVPNGLVVGCESLYVAYAPAHAGLLFACGALGMLSGDTVVGRFVPARWRARLGAPLRL
                     LLAAPYLLFALRPGLPVALVVAAVASTGFAASLLLQERLVALTPPELSGQALGLASSGT
                     MAMQGVGAAVAGGIAQLTSPATGMAAVAGLSVAVTSALAPGLGDRRAGGRGRLLGADGV
                     PPEPGAPDAPRAPRTKETS"
     gene            15456..16010
                     /locus_tag="I6J40_RS10955"
                     /old_locus_tag="I6J40_10945"
     CDS             15456..16010
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005314235.1"
                     /locus_tag="I6J40_RS10955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10945"
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_030112246.1"
                     /sec_met_domain="Mac (E-value: 6.1e-16, bitscore: 57.0,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSGELYLADDPELAADALHAAVLSERYNATSAADPEARRAVLAE
                     LLGEVGEEVDVRPPLRVDYGYQTTIGPRTFVNFGAVFLDVARITIGADVQMGPNVQLLT
                     PTHPVDPEPRRAKWEAALPITIGDNVWLGGGVIVCPGVTIGENTVVGAGAVVTRDLPAN
                     VVAVGNPARVIRAIGEETTEA"
     gene            complement(16331..16849)
                     /locus_tag="I6J40_RS10960"
                     /old_locus_tag="I6J40_10950"
     CDS             complement(16331..16849)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446870.1"
                     /locus_tag="I6J40_RS10960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10950"
                     /product="DUF4265 domain-containing protein"
                     /protein_id="WP_030195375.1"
                     /transl_table=11
                     /translation="MNLPAGPEHSPREADEIDADQIKVWFRFVPREGWLPQDTEGLWAR
                     RLGPDTARVDNVPFLQDGVAEGDTVRFRTDDDGLHWAVERVAASDNCTVRVLPVPSGPL
                     GRDARAVHERLAGFGLTGEVFSKEFPLLALTVPGGADLRGVKELLARGQDEGWWHFEVP
                     CSTETWREA"
     gene            complement(17037..17375)
                     /locus_tag="I6J40_RS10965"
                     /old_locus_tag="I6J40_10955"
     CDS             complement(17037..17375)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510172.1"
                     /locus_tag="I6J40_RS10965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10955"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_030195368.1"
                     /transl_table=11
                     /translation="MKAEPNAAGSADWNDLKREFDFTAEEVEQVEQRTAALLSEVRAYR
                     LAEVRKRQQMTQAAVAKTLGVTQGRVSAIEKGAINRSEVETLAAYVAALGGQLKIVADF
                     GDETLVLG"
     gene            complement(17372..17740)
                     /locus_tag="I6J40_RS10970"
                     /old_locus_tag="I6J40_10960"
     CDS             complement(17372..17740)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019762571.1"
                     /locus_tag="I6J40_RS10970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10960"
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_050494477.1"
                     /transl_table=11
                     /translation="MPYRVIVVEPARSWLHQLRRRDRGTLLQVAAAINVLQREGPALGR
                     PLVDRIVGSALPNLKELRPGSSGAGEVRLLFVFDPARNAVILVGGDKAGRWSRWYRTAI
                     KEAEAAYEAYAAPGNEES"
     misc_feature    complement(17696..17698)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17954..20071)
                     /locus_tag="I6J40_RS10975"
                     /old_locus_tag="I6J40_10965"
     CDS             complement(17954..20071)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379171.1"
                     /locus_tag="I6J40_RS10975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10965"
                     /product="hypothetical protein"
                     /protein_id="WP_205041599.1"
                     /transl_table=11
                     /translation="MSRETDSSSSGPQGRGGAAYPSGTPPYGSGQYPSPHSAQDGSDMD
                     PESVNPPRPEEPKTETTLTTRIRINIPGSRPIPPVVMRTPMAESDISGDRPDPERTSAT
                     PRPGTPPAAPAPMAADRSTGPDGGTPADRSRDAAPAAAEPPAEKPARERGGSDWFAPRK
                     APAPAPGTQPQGAGAPGGTGAPSGPGGPSGPGGPGGASDGGPGRPRPDLPYFSDAPQPG
                     GAPGQPGGGPGAPGPERSALDGYGADLPGGGPRMPGPSGPTTGPVTGTSSLTPNLDGVP
                     DIAGPGPGTGPMAPGGPGAHPPRLSDDTAILTPQAPAPEPGGHVSGDTLTSGIPVISGE
                     PRSTFPGGPRTPGGPGPGGPGVPGGPGSGPAAPRPAAQRPAPEPAPAPARKGRSKLVLL
                     GVAAVVLLGIAYGAGLLLNHAEVPKGTTVLGVDIGGGTKEEAVAKLDGALGERAKAPLQ
                     LSVDGKEEKLDPEKAGLTLDSQETVRGAAGSDYNPVSVIGSLFGGERPADPVIPVDEEK
                     LGVALNDLAGTSGSANDGTIRFEPNKAVAVPGKPGKRLDAAQSLISVRDAYRAQVQTGK
                     ARLVELPVTTSEPTITKAELDRAMKEFAQPAMSGLITIKAGPKQIQFGPARSLPQILSM
                     KAVDGRLVDVYDKQAIDELLDGVFDGIMAVKADGKEHEVGPDDVAQAMKTALTGTTEAE
                     RTVTIDLTGQG"
     gene            complement(20247..>20681)
                     /locus_tag="I6J40_RS10980"
                     /old_locus_tag="I6J40_10970"
                     /pseudo=""
     CDS             complement(20247..>20681)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956268.1"
                     /locus_tag="I6J40_RS10980"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10970"
                     /product="DUF6113 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="SSYAPRRNAPPREPEPVGFAARPNPARIAAYAGLAVVGALVGLAG
                     TLVQAAWFPGGLIIALAAAAGLFYGGRVLIRTQIGALAPAAGWFITVFLLLSGRPEGDY
                     VFGDELGLILFMLGGTAVAVICATTSRVPQSAMRSGRSGT"
     gene            complement(20906..21808)
                     /gene="mshB"
                     /locus_tag="I6J40_RS10985"
                     /old_locus_tag="I6J40_10975"
     CDS             complement(20906..21808)
                     /EC_number="3.5.1.103"
                     /GO_process="GO:0010125 - mycothiol biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mshB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455455.1"
                     /locus_tag="I6J40_RS10985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10975"
                     /product="N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-
                     D-glucopyranoside deacetylase"
                     /protein_id="WP_030195357.1"
                     /sec_met_domain="PIG-L (E-value: 5.9e-27, bitscore: 93.6,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLPDRRLLLVHAHPDDESINNGATMARYAAEGAHVTLVTCTLG
                     EEGEVIPPALARLTADRDDALGPHRVGELAAAMRELGVSDHRFLGGAGRYRDSGMMGAA
                     QNGRPGSFWSTPVDDAAAHLVEVIREVRPQVLVTYDPDGGYGHPDHIQAHRVAMRAAEL
                     AADPAYGSDAPHAVAKIYWNRVERRVVEAAFDRLRTTAPDAFPGIAAVDDVPGVTDGER
                     ITAEIDGSAYAGVKAAAMRAHATQIAVEEPYFALSNDLGQPLLTTEYYELVRGERGVAA
                     PVRESDLFAGLTGAGEDAA"
     gene            complement(21926..22120)
                     /locus_tag="I6J40_RS10990"
                     /old_locus_tag="I6J40_10980"
     CDS             complement(21926..22120)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190440.1"
                     /locus_tag="I6J40_RS10990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6J40_10980"
                     /product="hypothetical protein"
                     /protein_id="WP_026290246.1"
                     /transl_table=11
                     /translation="MALSISAVVLLAIIVFLLIRKSGLKGGHAVVCMLLGFYIASSSVA
                     PTISDLTSNVAGMISSIKF"
     misc_feature    22199..22214
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.78"
                     /tool="antismash"
     misc_feature    complement(22201..22214)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.12"
                     /tool="antismash"
     misc_feature    complement(22202..22217)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.19"
                     /tool="antismash"
ORIGIN
        1 cgggcgccgg cccgccgcgc tgaactgcac ccccgccacc gccacggcaa agggcccggg
       61 ggacgccggg cgggtgcgcg ccgagctggt gcgcgccttc ggcaaggagg tgctgccgac
      121 cgcgacggcc gcgggcgcct ccgccgcctc gaccgtctcc gtgcccgtcc cggcgacctc
      181 cgcgcaggcc gaggacgagg gcgtgccgca gcgcggctgg gagctggcgc actgggcggt
      241 cgcgcagtcc gaggcgctgc ggatcgagcg cgtgagctac gcggaccgcg tctgggaggc
      301 gggccggggc tggcggacag acagcgcgaa gggttcggaa acgggcacgg cgacggtcgg
      361 catccgggtc gctcagtagt acgccccgtc cctcgtacgg gccccggcgg cttcggcccc
      421 ggacaccttc cgcgccgatc gtcacgggcg ggcaccgctc ccccgattcc cttgtcgcac
      481 ttgagaagtg acggttcctc ggggcgcgac ggtatggatt gtttgcccgg gttgcatccc
      541 tgcggataat cggacgcatt actcactctt tacctttgcg gaccgcaacc tcccccgccc
      601 ccgcagcggt tgatcagtcc gtccggacca ccggacggac gcattcgtgc acaacccgct
      661 gaaggagcat catgtccctc cccctgaccc gtcggatcgc tcgtgccgcg ctgctgatcg
      721 ccgcaggcgc ggcccccgtg gtcggtgcgg ccggcgccgc gagcgccgca gagctcccgc
      781 agaccacgga cctgggcggc ctgacctccc tggacggcgc gagcgtcggc aacaccctcg
      841 acagcaccgc ccgccagggc accgaggcgg ccggccagac cggcggccgc ctcgtgggca
      901 ccgcgctccc ggccgccggc gagaccctcg gccgctccgc caaggtggcc gtcccggccg
      961 tccaggagac cgccgggcac accgcgggca gcgcgggcga ggccgtgggc ggggtggccg
     1021 aggccgccgg caagggcctg cccaccgact ccctcaccca gggcggcctg cccaccgacg
     1081 ccctgccgct gaacggcctg ccgatcggct gaccgccgcc cccacacgcg cgggaggccc
     1141 gaggagtgcg cactcctcgg gcctcccgcg cgttccggtc cctcccgcgc gttccgggcc
     1201 tcccgcgcgt tcgggcgcgg cgggtcagga caggcgcttg accgccgccg ccacccgttc
     1261 gtcggtcgcg gtgaacgcca cccggacgaa gcgctcgccc gccggaccgt agaagtcgcc
     1321 gggcgcgacg aggatgcccc gctccgcgag gtacgcgacg gtgtcccagc acggttcgtc
     1381 gcgggtcgcc cacaggtaga ggctggcctc gctgtgctcg atccggaagc cgtgcccctc
     1441 cagggccgcg cgcagggcca ggcgccggtc ggcgtaccgg acccgctgct cggacacgtg
     1501 cgcgtcgtcg ccgagggcgg cgacggtggc ggcctggacg ggggcggccg tcatcatccc
     1561 gccgtgcttg cggatcagca gcagctcccc gaggacggcc gcgtcgcccg cgatgaaggc
     1621 ggcccggtag ccggccaggt tggagcgctt ggacagggag tggaccgcga cgacgccctc
     1681 gtagtgcccg ccgcagacgt ccgggtggag caccgagacg gggtcggcgt cccagcccag
     1741 ctccaggtag cactcgtcgc tgaagaccag gaccccgtgc tcgcgcgccc acgcgacgat
     1801 ccgggtcagc tcctccttgg agagcacctt gccggtcggg ttggagggcg agttgagcca
     1861 gagcagcttc agcccggccg ggtccagctc ggtcgggtcg tcgtagacga cgggctccgc
     1921 gccgcagagc cgcgcgccga cctcgtacgt cgggtaggcg agccgggggt aggccaccct
     1981 gtcgcccgcg ccgagcccga gctgggtcgg cagccaggcc accagctcct tggagccgac
     2041 gaccggcagc acgttggcgt gggtgacgcc gaccgcgccg agccgccgct cgacccagcc
     2101 ggtgagcgcg tcccgcagct cctcggtgcc ccacaccgtg gggtagccgg gactgtccgc
     2161 ggcctccacc agcgcccgcc ggatcagctc ggggaccggg tcgaccgggg tgccgacgga
     2221 gaggtccacg atgccgtccg ggtgggcctg ggccgtcgac ttgtagggcg cgagcctgtc
     2281 ccaggggaag accgggaggc gggaggagac tgcggacacg gggctctgct ttctcgtgct
     2341 gatcgtgtac ggaccagggc acgccctggg cgcgtacggg gtgttccggt gcgggaaacg
     2401 cctcggtccc gcacggggac gagccgtacg ggaccgggct gtgcgcgtgg tgccgccgct
     2461 tactggttct gcgggggcag tccggcgatg aacgcgtggt cgcgctcgat gagaccgagc
     2521 ttggaagcac cgccgggcga gccgaggtcg tcgaagaact cgacgttcgc cttgtagtag
     2581 tccttccact cctccggagt gtcgtcctcg tagaagatgg cctcgaccgg gcagaccggc
     2641 tcacaggctc cgcagtcgac acactcgtcc gggtggatgt acaaggaccg ctggccctcg
     2701 tagatgcagt cgacggggca ctcttcgatg caggccttgt ccttcacgtc gacacaaggc
     2761 tgcgcgatga cgtaggtcac gctgtcgttc ctcctcggta gggcgttggc tctcgcgcgg
     2821 gagcgcggcg tcgtcgatgc ccacccctag tatctccgtt ctcgggcacg atccgaacag
     2881 gaggggcgga cagacctgtg gaattcacca tcggcggacg gctggacgtc cgcatcaccc
     2941 ccgctgacgt gggcaaacgc gtctccgtac gctgccggac ggagagcggc ggcgcgggcg
     3001 cggagttcac cgacacggtc ggagtgctca catcctggga ccgcgatgtg ctctccatca
     3061 cacgaaagag cggggagtcg gtccacatcg tggaatcctc cctcgtcgcc gggaagaccg
     3121 tgccccccgc cccggcccgc cggcgcggcc ccgccgcctc cttcgaggaa ctggccgccg
     3181 tcaccgcgcg cgcctggcag cccgtggaga gcgagccgct cggcgactgg cggctgcgcg
     3241 ccgcgggcgg cttcacccgg cgcgccaact ccgcgctgcc gctcggcgat ccggggttgc
     3301 ccgtcggcga ggcgctcgac cgggtgcgtg cctggtacgc ggagcgggac ctgcctccgt
     3361 acgtccagac ggcgaccggg gccgccggca cacaggaact cctgtgcgcg gagctggagc
     3421 ggcacgggtg gcggcgcgag gtgacggcgc aggtgcggat cgccgcgctg gcaccggtcg
     3481 gtgacggtgc ggcggacgtc gcggcggttc ggctgacccg tgcgccggac gcggcctggc
     3541 tcgcccgcta ccagcggttc tccaccccgg gcccgcacgt gctgcgggtg ctggaaagcg
     3601 gtccttcggt ctggttcgcc acggtcgcgg gggacggcgg tgctccggac gcgatcgggc
     3661 ggtgcgtggt agacggccgg tgggcggggt tcatggccgt cgaggtcgcc ccggaacggc
     3721 ggcggcgcgg actggccacc accgtgatga ccgcgctggc ccgccgggcc ctggacgagg
     3781 gcgcgtcggc ggcctggctc caggtcgagg aggagaacga gggggcgcgg gcgctgtacg
     3841 acggcatggg cttcgcgctc caccacagct accaccacta ccgcccgtcc ccggcgtgac
     3901 cgggagcgtg cggacggacc ggcgggtgga tcggcgcgtg tgagcgggga catgggcggg
     3961 gacgggcgaa cggccgggag cgggggcagg ggatgagcgg gctggattcc ggggcggcgg
     4021 agcggcggcg gcagttcgcc gaggaggccc gctcagagcg gccggacctc gccctgctct
     4081 gcctgctgct gggcgcggag gccgggcccg tcggcccggc cgaggtccgc ccggtggtgc
     4141 cgggggagac cgacccggac ccgtacggca tcgatgccgc gcagatcgag ctggaccggc
     4201 tggcggggct gctgccgtac ggaccccgct cccccgccgg ctgggcctcg gccctggcgg
     4261 aactgctggg cgggcggtgc gggttcggcg gctcggcggc cgactaccag cggctggact
     4321 cctcctgcct ccagcaggtg ctgcgccgcc gccgcggact gccgatcctg ctgtccgtcg
     4381 tctggatcga ggtcgcgcgc agggccggcg cgccggtgta cggggtggcg ctgcccggtc
     4441 acttcgtggt cggcttcggc gacccggacc acctggtgct ggccgacccg ttcgccgggg
     4501 gcgcgccgct gaccggggcg gacgcggaac tcctggtcac ctcgaagacc ggggcgccgc
     4561 ccgatccgtc gatgacgagg cccgcgcgcc cgctggagat cgtgctgcgc gtcctgaaca
     4621 acatccgggc gtgggcggcg acccgcccgg agcgcaccga tgtggcgctg tgggcggtgg
     4681 agctgtcgct gctgctgccc tcgcatccgg cgcggctgcg ctacgagcac gccgagctcc
     4741 tggttcagcg cggggagttc ctgcgcgggg cggcggagat ggaggagtac gcggacgtca
     4801 tggccggcat cgagccgacg gcggccgaga acatccggcg caaggcccga gcggcgcgcg
     4861 ccctgctcaa ctgaaccacc cggaaccggc cattcggcga gctttccgcg ccacccaggc
     4921 ggacggcaaa cggctacgtg tgcccgagta cccaggaaac agcgagacgg atgggtccgt
     4981 gagggctgtg cgctcccggt ttacatccga acgccccctt ccgcgcccaa cgggcgcact
     5041 attcggcccg tttgtcggcg tacgtggagg cccatgcgct caactggagt tccgtcaccg
     5101 gacgcgtaca gcccgtcgcg ttccgcgctg gacggaccgg atgagagaac ctgagggcag
     5161 agtgatgaca accgtgctgc tggtccacac cgtgccgttg tggcgcgctt cgctggcatc
     5221 gctgctctgc gcggggccgg acatagaggt ccggaccgcc gaacacggcg cgatacgcga
     5281 cgccctgggc gggccggctc cggacgtgct cctcaccgat ctcgactgtc cgggcgcgct
     5341 ggacgtcctc gacgaggtca agacggtgac cgcgccgcac ggcggtccgt acccgctggc
     5401 cgtgctcacg cgcagcgacc ggccgcgcgg tctgcgccgg gcgtacgagg cgggggcgct
     5461 cggctacatc gacaagtacc ggccggtgga cgacctgtcg gaggtgatgc acaagctggc
     5521 ggacggcggg cggcacatcg acgagtcgct ggcgttcagt ctgctgcagg tggcggacat
     5581 gccgttatct ccccgggagt tgagcgtgct gtcgctggcc gagggcggcg acacggtggc
     5641 cgggatcgcg gcccggctcc atctgacgcc gggcacggtg cgcaactacc tggccgccgc
     5701 catccgcaag tccggggcgc gcaaccgcct ggacgcgatc agacgggcga aggaggcggg
     5761 ctggatctga cgccccgctc ctcgtccccg gaaccgatcg acgcgtcctg accggtaccg
     5821 accgtcccga gccgaccggc gacggccacc gcgtcctgtg cgtccggtac gaggccaccg
     5881 ccccgcgcgt ccgcgtcctc cggctcccag aggccggcca ggtcgcggta gagggcgctg
     5941 gagcgcagga gttgtgcggg ggttccgcac cgggtgcgcg gaccgtccat caccagggtc
     6001 cgcccggcgc ggcgggccga gctgagccgg tgggcgacga cgacgagcgc ccccggcagg
     6061 gcggcgcacg ccagctcggc ccgggtctcc gccgccgggt cgagcctgct ggtcgcctcg
     6121 tcgaggatca gcaggggcgg cgcggcgagg taggcccggc ccagggcgac gagctgccgt
     6181 tcgccctggg agagccggtc cggcacgacg tccgcgtcca gggagccgag ccgggagagc
     6241 agcggctcca gcccgatcgc ctccgccgcg tccgcgatct cccggtcgcg ggcgtcgggg
     6301 ctcaggtagc ggaggttgtc ccgcagggag ccgctgaaca cgtaggcgtg ctggggcagc
     6361 agtacccgta cggaggtggc gtcggccgcg cgcaccggcc gcccccgcca ccgcaccgct
     6421 cccccggtgg gcggttcgac cccggcgagg acggcggcca gggtggactt gccgctgccg
     6481 ctcggtccga cgaccgcgag gtgctcgccc ggcgcgatcg tcagggagag ccggtccagg
     6541 acgggctggg cgcggggccc gtaggcgaag gtgacctcgt ggagttcggc gaccggggcg
     6601 ggggcgcggc gggcggacgg ggcgggggcg ggcacggcgg ggtgggcggt ctggtcggcc
     6661 ggtggcgggg cgctgtcccg tacggcctgc ggcgggtcgt cctcgggcgg gggcggggcg
     6721 tttgtgaagc ggtccaggac cacgacgagg cggcccccgg cggtccccag catggtcatc
     6781 agcgcctgga cggcgggggc gagcgcctgg gtgagatagg tcagcgcgcc gaccagggcg
     6841 cccgcggtca ggccgttccg cagcagccag ggcgccgcga ggagcagcag gagcgggggg
     6901 aagcggccgc agacggcgag ggccagcacc cggacggccg accagcgggc cagcgaccgg
     6961 gaggcggcga gctgggcttc ggccagggcc ccggactccg ccacggtccg cccggcggtt
     7021 ccggcggcgg cgatgtcgcg tacggaggcg gccagttcgc cggcgtgcgc ggcgtacgcc
     7081 tcgtcggcgg cgaggtaggc gcgctggcgg gcggccatcg ggggcagggt ggcgaggaac
     7141 agggcggccc ccacggccag cggcggcagg acgatcagga gcagggcggg cgcgagggcg
     7201 agcagaccgg tgacggcccc ggcggcggtg aaggcgaacg agcgcagcgt cagcacgagt
     7261 ccggcccagc cgtcccgggc gatctcactc tgatgggtga cctgtgagag ggaccgcgtg
     7321 ctgacgtccc cggagcggcc gagcgcgccg ccgagcgccc gggacaccgc gcgccggacc
     7381 agtccgtcgc gcagcggctc caccaggtcc gcgagccgcc cgaacacccc gcgtgcggcg
     7441 agcacggagg gcaggacggc gaccgcggcg acggccagcc agcagaggcc ggtcgccggg
     7501 cgtgaggcga ggaagccgtc atcgagcgcg cgggcgaccc cgtacccgct gaggaaggtc
     7561 tgcgcgaact ccagcaggga ccagccggcc agccgcagga ccgcccccgt gcgcgcccgc
     7621 aggaaggggc gggcctcccg ggcgacgcgg cgcagcgcgg tgtcgcgccg ggggcgcggg
     7681 gccgtggggc cgttcgcctt caccgggccg cctccgctcc ggtcggctgg tggggggtgt
     7741 tcggtccggt gggttggtgg agcgggtggg ggccggtggg ttcgtgggac gccttcgcat
     7801 cggcccgttc ccgggtcgcg tccggcgctg tccgttcgcg gggcgtgtcc ggcccggtcg
     7861 gttcgcggga cgccttcgca tcggcccgtg cctgggtcgc gtccggcgct gtccgttcgc
     7921 gaggcgtgtc cggtccggtc ggttggtgga gcgggtgggg gccggtgggt tcgtgggcgg
     7981 tttccgtctc ggcgcgcgcc cgggtcgcgt ccgccggttc gtcgcggaag accgcccggt
     8041 actccggatc ggcccacagt tcgtcgtggc ggcccgtcgc gcggagcctg ccgtcctcca
     8101 gccaggcgac gcggtcggcc cgcgcggccg acgacagccg gtgggccacg atgatccggg
     8161 tgcagcggcc ggcccgcgcg tcgagggcgc gccggacgtg gtgctcggtc acggtgtcga
     8221 ggctggacaa cgcgtcgtcg aggatcagca gccggcccgg gtgggcgaac gcgcgggcca
     8281 gcccgaggcg ttggcgttcg ccgcccgaga ggggggcgtc ggcgagcggg gtggcgtagc
     8341 cgtacgggag cagggcgacg aacccgtcgg cgcgggccgc gcgggcggcc tcgcgtacgg
     8401 cgtcgggcgc ggcggtccag gggccgtggg cgatcgtgtc ctcgacggtg gtgccgggga
     8461 gggccgggcg ggcgaaggcg tacgccacct cgcggcggag ccgggccggt tccatgccgt
     8521 ccagcgggac gccgtccagc agcacatggc cggtgtccgg gtcgaggagc cgcccggcga
     8581 ccgcggcgag ctgcgacttg ccggagcccg agcgcccgac gacggccagg gacgtaccgc
     8641 cggggacggt cagatggacg ccggtcagca acgggacgcc gtcctgttcg acgccgacgt
     8701 cccggagttc gagctctccg ggggcgtccg ggaccggtcc caggccgcgg tgcggcagcg
     8761 gggcgagggc gaggagcggt tcgagggcgg tggcggcggc gcggctgcgg gcgagcgcac
     8821 cgagggcgcc ggtcagggag ccgatgccga cggcgaggct cgcgtagcgg gaggcggcga
     8881 ccaggtcgcc gacgccgatc gcgcccgcgc cgaggcggag tccggcgacc gcgaggacca
     8941 gcagcatgag caggggcagc aggagtccgc tgcggcccac ggcccgcccg tacacctccc
     9001 acgtacgcct gccgtgttcg gcgagggcgg tcaggggttc caggacgcgg cggtgttcgc
     9061 gggcggcggt gcgggcggcc cggatggtgt cggcgccctc cagggcctcg gtcagccggt
     9121 gggcgatgag cgactgggcc cgctggtagt cggccccggc gtcggcggtc ccccgggtga
     9181 aggcgcgcag caggacgacg agcaggggcg cgcccacgag gagcgcggcg gccgtccaca
     9241 cgtcgatgag gaggaggccc acgagcgcgc cgagcggcag caggacgccc gcgacggctc
     9301 cggcggcggt ggccggggcg gcggcggcgt cggcggtgcg ggcggtgagc cgggcggtca
     9361 ggtcgccggt gggcagcgcg agggcgcggc ggggctcggc ggtcaggacg cgggcggcgg
     9421 tgcgggtgcg cagggacgcg gtgagccggg cggtggtggt cgtgccggtc acggcggcgg
     9481 ccgcgtcgaa cccggtctcg gcgagggtga gggcggtgca gagcagcagc ccggaccagg
     9541 gcacgggacc gccggagacc agccggtcga cggtgtggcc gagggcggcg ggaagggcga
     9601 gggcggccag cgcgccgccg gtggagcaga ggaacagcca ggtcagggcg gccgggtgcc
     9661 gccgggagag ccgccggacg ccggacgcgg ggcccggtcg gaggtgcagc ggcacgggtc
     9721 gcctttctgg tcggcgggac ggccgcgggg acgtcccggc cgcgcggtcg gcgccgggcc
     9781 ctcgcgggca cgtggccggc cggcccatcg gcggtgctcg ccgatgggcc ggccggggtg
     9841 gttcacgggg tgcagaggac cacgctgagc gagctgtact cgcagaccag caccgagacc
     9901 tggctgcccg tggcgagctc gccgaacgag tcctcggccg gggtgtccat cgcctggagg
     9961 tcgagaagcg ccatgatgat gtcctttcgg ggacggttgc ttactgaacg gtggtgttgc
    10021 cacgacccct ggaggggccg gtctgtgggg ccgctggagc ggccgggtgc gccgccgggg
    10081 cggcgggcag gaagggaagt ccgatcgggg cgccgtgcgc ggcccccagg gcgaggagcg
    10141 cgccggcggt cccggtggcc aggtccatcg acaggcgcat cagctgttcg ccggggaagg
    10201 cgagtccgcc gccgtcggtc agggcgtggc tcgccagcag gtcgaggtgg cggtcgatcg
    10261 cgcggagccg gtcggccggc tccgccagcg gggtgaccgc gaggtgggcc aggagtccgg
    10321 cggagccccg gaacagtccc ggctgcacgt agaaggcgga gcaggcggcc ggcaggaggg
    10381 cgcggcccgc ttcttcgagc gcggggtccg gccgctgggc caggtaggca tcgatgacgg
    10441 cggctatccc ggcgctgccc gaaccgaggt acggcatcag ccgtttgccc tcgacgacga
    10501 ggagttcgcc gtcgtcgccg gcccggcacc gctccaggtc gcggtggagc gcggcggcgg
    10561 ccaggtcgag gagggcggtg tccccggtgt tctcgtaccg gcgtatcagc agcagggcga
    10621 cgccgctcgc gccgtgcagc agtccggtgc ggggcgaggg agggccctcg gtgagcgcgc
    10681 ggacggcgaa ggcggtgcag cgggcggcgg cggcggagag ggccggggcg tcggggccgg
    10741 aggcggtgcg ggccaggtcg tcgagggcga ggccgatgcc cgcgtacccg ttgtgcaggc
    10801 cgggcgccag gccctccagc ggctggtcga ggacgatccg caggaggtcg gcggcctcgg
    10861 cggtgcggcc gagccggtgc agggtccagg cgatgccggt cagcccgtcg tagaagccga
    10921 gggggctgcc ggacgccggg gccttggcgt ggcgcaggag ccagtcctcg gcggccgggc
    10981 agggcggggc gccggtctcg tggagggcgt agagcacgcc ggccgccccg tacgcgaagg
    11041 actggccgcc ggtggccgtg gcgaactggg cgatgtcccc ggggaagcag cggtcgtcgc
    11101 gctccggcgt acaggaggcg gcgatggcgg cggccatggc ctcccgggcg cgcggccatt
    11161 cccggaggtc gggcccggcg gcgtcggcgt acgggccggg tgcggcggtc gctgcgtcgg
    11221 gcgtacgcgg ggcggtcgag gcgtcggagg tacgcggacc gggtacggcg gcgtgcggcg
    11281 gggcgtccgt cgcggcggtc gcgtccgcct cgcccgtccc ccgcaggatc tcggcgaccg
    11341 ccggccgcag cgcctcctcc gtgaccggga agacgcgggc gatgtcccgg gcgagcccgg
    11401 ccgccttggt gcggtcgatg ccgaacagcg tggtgagcgg gaggtacagg gcgagccgca
    11461 ggcaggccag cgcgtaccgg tcgatgtcgg tgccgcgccg gtcggccggg gcgacgaagg
    11521 ccgggttggc gacgatctgg cgtcggcggt cggccgccgg gaaggccgcc tcgaagtcga
    11581 gcagggcgat ccggccgctc tcctcgtcga ccatgacgtt gctcatgtgc aggtcgctga
    11641 tgacgatgcc ccgggcgtgg accgcctcga cggcgcgctc cacctgcccg tggacctcct
    11701 cggcccacgc cgcgtgggcg gcgagcagtt cgggcgaggg gtgccgccgg gcgagcggga
    11761 agcggcgggc gaagacggtg ttgagggtgg cgccgggcat gtactggagg accaggaagt
    11821 ggtggtcgcc cacctcgaag gcgtccttga cctccggcac gcactccagc ccggcgaggt
    11881 gttccagggc ggtccgttcg cggtccagcc gggcgacggc gtccgccccg tcggcggcca
    11941 gtccggcgta cgggcgggcc tccttgagga cgacctgctc gccggtgcgg gtgtcgcggc
    12001 ccaggtagac cccgccgccg ttggagaagt gcagcgcctt ctccacggtg tacgggaggt
    12061 cgccgaggcc cacggcggcg cgggcttcga ggtgcggggc caggaaaccg ggcggcgtca
    12121 cccaggaggg gatgcggaag gcggggcccc ggtcgtccgg gacgagccgg ccccgggggt
    12181 cggcgacggc cggcaccggc cgcccgtccg ggccggagca gaaacgggcg gcgaacgccc
    12241 cgtagcgggt gtgcacggga ccgttcccgc agcgcaggtc gctcaggatg tacggtccgt
    12301 gctcgccgtc cagcagctcc atgagggcgg tgcacacctc ggggaacgcc tcgtcggacg
    12361 gcgggtagac ggtgatgaac ttcccgctgc ccgcccggtc cgcgtacttg gcgttccgca
    12421 gggccagcag ccccgggttc ggtacgcact tgaaggccag ccggtgcgcc agacagtggg
    12481 cgacgacccg ctccagcacc gagtccgcgt tgtcgagggc ggcggatatg tgcagcttcc
    12541 agccctgggg cggcaggcgc agcccgtcgg ggctgtacga gagccagtcg ccgcgccggg
    12601 agcgggtcca cccctggggg gcggcgcctc ggacggccgg gtagaacgcg tgctcctcac
    12661 caccggcgcc cccggccggc tggagggcgc ggtggggtgc gtcgtagaag cggcggtccg
    12721 cctggcagta cgcggcgtac tccggattca cgcacgttcc cctcgctcgg ttcggtcgcg
    12781 gcgagagaga aattgtcata acgacgagcg gtgcccatag tcacggttgt cacgagtcgt
    12841 acatgcacgc caaccgtcac cgcacatgcg aagcgcacgg gttaccggtg cgtaccccct
    12901 tccgcgcagg tacggaccgg tgcggaccgg ggggcgcacc ggggcgtgcg cccggcgctt
    12961 tcggtgccgg tcagctcgcg ctgcgcacca ggacgtcgcc cgcttccgta cggacgtaga
    13021 gcacggagcg gcccgcgcgg cgccggcgga ccaggccggc gtcccggagg acccgcagat
    13081 ggcggccgac cgagcccagc ccctggccgg tcagcgcgac gagttgcgtc gtgctgagcg
    13141 gcgaggccag cagcaccagg accgccgccc gcgccgcgcc gagcagcgct cccagcgcgg
    13201 tcggtacggg gccgcgcccg gcgtcggtga gcgcgccgga gcacgggtac accagcgcgt
    13261 accggcgcgg gatgtcccag ccgacccagc actggttcgg ggtgacgggg acgaacagca
    13321 gctcggcgcg gcccagttcg cggggcgggt tgtcgtaggc gttgatctgg aggcggctct
    13381 cgccgagcca gcggatgccg gggcgcatgc cgttcagcgc ttcggcccag ccgccccgtc
    13441 ccaggtgggc cgtccgcgcg accacatcgg cttcgagcac ccgccgccgc ctcggccagt
    13501 cgggcagcac ggtgtgcgtc cagacccacg cgacggcgtc ggcggcacgg tcggccaggt
    13561 cgtcccggtc gagcgcggcg gggagcgggc cgccgcccag ggtcaccgcc aggtcggcgc
    13621 gggcctggtc gggcggggtg gcccgcatcc gggccagttc ctcggcgaag gcgggcgcgg
    13681 gccggccggg cggggcgggg acgggggcgg cgcccaggaa gtcggcggtc cagcgaggtg
    13741 cgagggcgga ccggatcacc agcgcggaga ccgggtcctc ggccgcccgc cgccggtagg
    13801 cgggcaggtg ctccgccagc caggcgcgct cccccgggtg ggcggcggcg gcccgctcca
    13861 ggagcagcag actggcgacg gcctccgcga gcggtgagac gacgaaccgg ctcccggcga
    13921 gggtgtcggc gctgatctgc caccagccca tcccgctctc caccgccctg ttcgctcgtc
    13981 tgctcggtct gctcggtctg ctcggtgcgc gccgtggtga cggccgcacc gtccgctcgc
    14041 gctcggcatg cggtgtgcgg gggctccgcc tgcgcggcgg ccccgggctt tcgcgtccgc
    14101 gcgaaacagt aacggcctcg gcggcggcct ccgcagactc cggtcatgcg cacctaccgc
    14161 gagctgttcc ggaccccgga gttcaccccc ttcttcacgg ccgtctcggt ccagacggcc
    14221 gcccacaccg cgaccggcct ggcgctgggc accctcgtgt acacgcgaac gggctcgccc
    14281 ctgctgtcgg cgctggcgat gttcggcccg tcgctggccc aggcggcggg ggcgctcacg
    14341 ctgctctcgg cggcggaccg gctgccgcca cgcgccacgc tgaccgcgct ggccctgctg
    14401 tcggcggtgg ccgcctgtgt gcaggccgtg cccggactgc cgctgtgggg agccttcgcc
    14461 gtgctgctgg tggtcggggc ggccgggtcg gcgggcggcg gggtgcggta cgggctgctc
    14521 aacgagatcg tgccgcgcga ggggttcctg atcggccgtt cggtgctcaa catgacgggc
    14581 ggcgcgatgc agatctgcgg gttcgcggtg ggcggggcgc tggtggcggt ggtctcggcg
    14641 cgcggcacgc tgctggtcgg ggccgccctg tacgtcgtcg cggcggccgt gacccggttc
    14701 ggcctgtcgg cccggccacc gagggccccg ggccgtccct ccgtccgcga gacccggcgc
    14761 acgaacgcgc tgctctggtc gtcggtcccg cgccgatacg tgttcctggc gctgtgggtg
    14821 cccaacgggc tcgtcgtcgg ctgcgagtcc ctgtacgtgg cgtacgcgcc ggcgcacgcc
    14881 gggctcctct tcgcctgcgg ggccctgggg atgctgtccg gtgacaccgt ggtggggcgg
    14941 ttcgtgccgg cccggtggcg cgcccggctc ggggctccgc tgcggctgct gctggccgcg
    15001 ccctacctcc tgttcgcgct gcgcccgggg ctgccggtcg ctctggtggt ggcggccgtg
    15061 gcgagcacgg ggttcgccgc gagcctgctg ctccaggaac ggctggtggc gctcaccccg
    15121 cccgagctga gcggccaggc gctcgggctc gcctcgtcgg ggacgatggc gatgcagggg
    15181 gtgggggcgg ccgtggccgg cggcatcgcc cagttgacct cgcccgcgac gggcatggcg
    15241 gcggtcgcgg ggctgtcggt ggcggtgacg tcggcgctgg ccccgggcct gggcgatcgt
    15301 cgcgcgggcg gacggggcag actgctggga gcggacggag tgcctccgga acccggagct
    15361 cccgacgcgc cgcgcgcacc ccggacgaag gagacgagtt gagccacgag accaggcccg
    15421 gccaggacga cggcaggccc agccagaagg aggccatgct ctccggcgag ctgtacctcg
    15481 cggacgatcc cgaactggcg gcggacgcgc tgcacgcggc cgtcctgagc gagcgctaca
    15541 acgccacgtc ggccgccgac cccgaggccc ggcgcgcggt cctggccgaa ctcctcggcg
    15601 aggtgggcga ggaggtggac gtacggccgc cgctgcgggt ggactacggc taccagacca
    15661 ccatcgggcc ccggaccttc gtcaacttcg gcgcggtctt cctcgacgtc gcccgcatca
    15721 ccatcggcgc ggacgtccag atgggcccga acgtccaact gctcaccccg acgcacccgg
    15781 tcgaccccga accgcgtcgc gccaagtggg aggcggccct gccgatcacc atcggcgaca
    15841 acgtgtggct gggcggcggg gtgatcgtct gccccggggt gaccatcggc gagaacacgg
    15901 tggtcggcgc gggcgcggtg gtcaccaggg acctgcccgc gaacgtggtg gcggtcggca
    15961 acccggcccg ggtgatccgc gcgatcggcg aggagacgac cgaggcgtga cgcgccgccg
    16021 gcccgccccc ggacgaggcc ggccgatccg cgccccggac gcgctgaggc ccgccggccc
    16081 gtaccccgta cgcgctgaga cccgccggcc cgccgggttc cgcgccccgt acgggcccgc
    16141 cgggttccgc gccccgtacg ggaccggcgg gttccgcgcc ccgctcccgc ttgagacccg
    16201 ccggcccgcc gggatccgca ccccgggtcc ggaccggcgg gcgggcctca cgcccccggg
    16261 gcctgcccgg cgaccacgcc ccgcgggcct cacgcctccc gaaccggcca ggtgatcgcc
    16321 ccgcgcggtc tcacgcctcc cgccaggtct cggtggagca cggcacctcg aagtgccacc
    16381 agccctcgtc ctggccccgg gcgagcagtt ccttgacccc gcgcaggtcc gccccgcccg
    16441 gcacggtcag ggcgaggagc gggaactcct tgctgaagac ctcgcccgtg aggccgaacc
    16501 cggcgagccg ctcgtgcacg gcgcgggcgt cgcgcccgag cggaccggag ggcaccggca
    16561 gcacccgtac cgtgcagttg tccgacgccg ccacccgctc gacggcccag tgcagcccgt
    16621 cgtcgtccgt ccggaaccgt acggtgtccc cctcggcgac cccgtcctgg aggaagggca
    16681 cgttgtccac ccgcgcggtg tccggaccga gccgccgcgc ccagagtccc tcggtgtcct
    16741 gcggcagcca gccctcacgc gggacgaacc ggaaccagac cttgatctgg tcggcgtcga
    16801 tctcatcggc ttcgcgggga gagtgttccg gaccggcggg gaggttcatg gccccatcgt
    16861 ctcgcgtacg cgcgacacac gcgaagcgcc cccctcaccc gcgccaccgc gaccggacgc
    16921 gacgtcttcc cgctacggac ccacggagcc cgtacgagga cgcaccgacg actccgcccc
    16981 cggccggggt tcccggggag agggcagcgg ctcggtctgt tcagccgccc cgtcgctcat
    17041 cccaacacca gcgtctcgtc tccgaagtca gcgacgattt tcaactgccc tcccagcgca
    17101 gcgacatacg cggcaagggt ctcgacctcg gatcggttga tcgcaccctt ctctatggcg
    17161 gagactcgcc cctgcgtgac tccgagcgtc ttcgccacag cggcctgtgt catctgctgg
    17221 cgcttgcgca cctcagccag ccggtacgcg cggacctccg acaggagtgc ggccgtacgc
    17281 tgctcgacct gctcgacttc ctcggcggtg aagtcgaact cgcgcttgag gtcgttccag
    17341 tcggcggaac ccgccgcgtt cggttcagct ttcatgactc ctcgttccca ggcgccgcgt
    17401 aagcctcgta agcggcttcc gcttccttga tcgccgttcg gtaccacctg gaccagcggc
    17461 ccgccttgtc acctcccacg aggatgaccg cgttgcgcgc ggggtcgaac acgaaaagga
    17521 gcctcacctc gccggcccct gacgatcccg gtctcaactc tttcaggttc ggcaaggccg
    17581 agccgacgat gcggtcgacc agcgggcggc ccagcgcagg cccttcgcgc tggagaacgt
    17641 tgatcgccgc cgcgacctga aggagcgtgc cccggtcacg tcggcgcagt tgatgtaacc
    17701 agctcctcgc cggttccaca acgatgaccc tgtacggcat tcaccctctc cagccagcca
    17761 aaacatcaca ctcgcatgat atcacgcttg tgtactattc gctcgtcgtg accgttgcgg
    17821 ggcgagcccg ccgttcgtcc gggcggcgac cacgtcgcaa cgcgcgcccg ggaaccccgg
    17881 ccgacgactc cgcccccggc cggggttccc gggcgggggc ggagaggggt gcgggtggag
    17941 tggtggtgcg gggtcagccc tggccggtca ggtcgatggt gaccgtgcgc tcggcctccg
    18001 tcgtgccggt cagggcggtc ttcatcgcct gggcgacgtc gtccgggccg acctcgtgct
    18061 ccttgccgtc ggccttgacc gccatgattc cgtcgaagac gccgtccagc agctcgtcga
    18121 tcgcctgctt gtcgtagacg tcgaccagcc tgccgtccac ggccttcatc gagaggatct
    18181 gcggcagcga ccgggccggg ccgaactgga tctgcttcgg gccggccttg atggtgatca
    18241 ggccggacat cgcgggctgc gcgaactcct tcatcgcccg gtccagttcg gccttggtga
    18301 tggtgggctc gctggtggtg acggggagtt cgaccaggcg ggccttcccc gtctgcacct
    18361 gggcccggta ggcgtcccgg acggagatca gggactgcgc cgcgtcgagc cgcttgcccg
    18421 gcttgcccgg caccgccacg gccttgttcg gctcgaagcg gatggtgccg tcgttggccg
    18481 aaccggacgt gcccgccagg tcgttcagcg ccacgccgag cttctcctcg tcgaccggga
    18541 tcaccgggtc ggcgggacgc tccccgccga agagcgaacc gatcaccgag acggggttgt
    18601 agtcgctgcc cgccgcgccg cgcacggtct cctggctgtc cagggtgagc ccggccttct
    18661 ccgggtcgag cttctcctcc ttgccgtcca ccgacagctg gaggggcgcc ttggcgcgct
    18721 cgccgagggc gccgtcgagc ttggcgaccg cctcctcctt cgtgccgccg ccgatgtcga
    18781 cgccgagcac cgtggtgccc ttggggacct cggcgtggtt cagcaggagg ccggccccgt
    18841 acgcgatgcc gagcagcacg accgcggcca cgccgagcag gaccagcttg gagcggccct
    18901 tcctggcggg ggcgggggcc ggttcggggg ccgggcgctg cgccgccgga cgcggcgccg
    18961 ccgggccgga cccgggaccg cccggaacgc cggggccacc cgggccgggg ccgccggggg
    19021 tgcgcgggcc gcccgggaac gtggagcgcg gttcgccgga gatcacgggg atgccgctcg
    19081 tcagcgtgtc acccgagaca tggccgccgg gctcgggcgc cggggcctgc ggcgtgagga
    19141 tcgcggtgtc gtcggacaac cggggcgggt gcgcaccggg gccgcccggg gccatcggcc
    19201 cggtgccggg accgggtccg gcgatgtccg ggacgccgtc gaggttcggg gtcagcgagg
    19261 acgtaccggt gaccggtccc gtggtggggc cggacggtcc gggcatacgt ggaccaccgc
    19321 cgggcaggtc ggcgccgtag ccgtcgagcg cgctgcgttc ggggccgggc gcgccggggc
    19381 cgccaccggg ctgccccggt gcgccgccgg gctgcggagc gtccgagaag tacggcaggt
    19441 cggggcgcgg ccggccggga ccgccgtcgg acgcgccgcc ggggccgccc gggccggaag
    19501 gaccacccgg tccggagggt gcgcccgtgc cgcccggcgc tcccgcgccc tggggctgcg
    19561 ttcccggcgc gggggccgga gccttgcgcg gggcgaacca gtcgctgccg cccctctcgc
    19621 gggcgggctt ctcggcgggc ggctcggcgg cggccggagc ggcgtcccgg gaccggtccg
    19681 cgggcgtccc gccgtccggc cccgtcgaac ggtccgccgc catcggcgcc ggcgcggccg
    19741 gcggggtgcc gggccgcggg gtcgccgagg tgcgctccgg gtcggggcgg tcgcctgaga
    19801 tgtcgctctc cgccatcggc gtgcgcatca cgacgggcgg gatggggcgc gatccgggga
    19861 tgttgatccg gatgcgcgtc gtcagcgtcg tctcggtctt cggctcctcg ggccgcggcg
    19921 gattcacgga ttccgggtcc atgtcggagc cgtcctgcgc cgaatgcggc gacggatact
    19981 ggccggatcc gtacggcggc gtacccgacg ggtacgcggc tccaccgcgc ccctggggcc
    20041 cggaggacga actgtcagtt tcacgactca aagcaggttc tcccgattgg ctccgccgcc
    20101 cgtacttccc ccatgccgca ggccagggga cggctcggcg cgcgcaccac catactggcc
    20161 gccgccgccg gacactccgc gaccggggga aacctccccc ttcgcgtcac acctctgagg
    20221 accgttcacg gccccgactt ggcacttcac gtaccggacc gaccgctgcg catggctgat
    20281 tgcggcactc tggacgtggt ggcacagatc acagcgacgg cggttccgcc gagcatgaag
    20341 agaatcaggc cgagttcgtc gccgaagacg tagtcgccct ccggccggcc gctcagcagc
    20401 aggaacaccg tgatgaacca gccggccgcc ggggccagcg cgccgatctg ggtccggatc
    20461 aggacccggc cgccgtagaa gagccccgcg gcggccgcca gcgcgatgat caacccgccc
    20521 gggaaccagg cggcttggac gagggtgccg gcgagtccga cgagcgcgcc gacgacggcg
    20581 aggcccgcat aggccgcgat ccgggccggg ttgggccggg cggcgaaccc gacgggctcg
    20641 ggctccctgg gcggggcgtt ccgtcgcgga gcgtacgagg acggggagga ggaggcggaa
    20701 gcggacgacc gcgcccggac gcgccccttg ccctcacggg ccttcccggc ggaccctccg
    20761 gcgttcccgg cggacccacc gccgttcccg gcctgcccgg tgccgccgcc cttcccgacg
    20821 gaccgaccgc cgttccctgc ctgcccggtg ccggcgccct tcccgacgga cccaccgccg
    20881 ctcccggcct tcccggtgcc gccgctcatg ccgcgtcctc cccggcgccc gtgagcccgg
    20941 cgaacaggtc gctctcgcgc acgggcgcgg ccacgccccg ttcgccccgc accagttcgt
    21001 agtactcggt cgtcagcagc ggctggccga gatcgttgga gagcgcgaag tagggctcct
    21061 cgaccgcgat ctgggtggcg tgggcgcgca tcgccgccgc cttcaccccg gcgtacgccg
    21121 atccgtcgat ctccgccgtg atccgctccc cgtccgtcac gcccggtacg tcgtccacgg
    21181 cggcgatacc cgggaaggcg tccggcgcgg tcgtgcgcag ccggtcgaag gcggcctcga
    21241 ccacccggcg ctccacccgg ttccagtaga tcttcgcgac cgcgtgcggg gcgtcggagc
    21301 cgtacgccgg atcggcggcc agctcggcgg cgcgcatcgc gacgcggtgg gcctggatgt
    21361 ggtcggggtg gccgtagccg ccgtccgggt cgtaggtgac caggacctgg gggcggacct
    21421 cgcggatgac ctcgacgagg tgggccgcgg cgtcgtccac cggggtggac cagaaggaac
    21481 cggggcggcc gttctgcgcg gcgcccatca tcccggagtc ccggtagcgg cccgctccgc
    21541 cgaggaagcg gtggtcgctg acaccgagtt cacgcatcgc cgcggccagc tcgccgacgc
    21601 ggtgcgggcc gagggcgtcg tcccggtcgg cggtgaggcg cgcgagggcg ggcgggatga
    21661 cctcgccctc ctcgccgagc gtgcacgtca ccagggtgac gtgggcgccc tcggccgcgt
    21721 acctggccat cgtggcgccg ttgttgatcg actcgtcgtc ggggtgcgcg tgcaccagca
    21781 gcaggcggcg gtcggggagg tccttcatgg ggaccaccct acgagccccg gaggccccgc
    21841 ggtgacctcc gcccccgcca ccggcacgcg caccgcgccc gcgcccgccc tcacgcccgc
    21901 ggacgcgcgg gcggcggacc ggcggtcaga acttgatgct gctgatcatc cccgccacgt
    21961 tgctcgtcag atcggagatg gtcggcgcga cggacgagct cgcgatgtag aacccgagca
    22021 gcatgcagac caccgcgtgc cctcccttca atccggattt ccggatcagc aggaagacga
    22081 tgatcgccag cagcactacc gccgaaatcg agagcgccac ggcggttcac ctccatcggt
    22141 acgttcggac ggtcggaacg ggggtacacg ctcggcaggt atctacccac cgagcgctac
    22201 ggatcataac tatccgtgcc aacgcattga tcggggcaca gcagcacgag gggcgcacgg
    22261 accggcccgc gcggataggt tcggtgccat gacctcgcag aagctgtcct ttccccgcca
    22321 gcaggctcgc acccagcgct tcaccctcgg cgcccctcgg gccttcaccg tctcaccgga
    22381 tgagacgcgc gtgatcttcc tgcggtccgc ctccgggacg gaccggacca accggctctg
    22441 ggtgctcgac ccggcgaccg gcgaggagcg cgtcgccgcc gatcccgagg ccctgctggg
    22501 cggttcggcc gagaagctgt cgccgcagga gcgggcccgg cgggagcgga cccgggaggg
    22561 ttcgtcgggg atcgtctcct acgcggtgga cgcggcggtg gagttggccg ctttcgccct
    22621 gtccgggaag gcgtacgtgg ccgagttgcg ggccgggacc gcacgggcgc tgcccgtgcc
    22681 cggcccggtg atcgaccccc gcccgtcccc ggacggccgg cacgtcgcgt acgtggcgaa
    22741 gggcgcgctg c
//
