LOCUS       NZ_JAFFHJ010000004     26012 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptococcus suis strain K11-WJ Scaffold4, whole genome shotgun
            sequence.
ACCESSION   NZ_JAFFHJ010000004
VERSION     NZ_JAFFHJ010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 272354)
  AUTHORS   Ma,J., Bai,Q. and Yao,H.
  TITLE     A type VII secretion system of Streptococcus suis contributes to
            colonization and the competition between bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 272354)
  AUTHORS   Ma,J., Bai,Q. and Yao,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) Department of Veterinary Microbiology,
            Nanjing Agricultural University, No. 1 Weigang, Nanjing, Jiangsu
            210095, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CANU v. 1.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 171.5x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016905205.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 03:58:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,194
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,095
            CDSs (with protein)               :: 2,095
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 9 of 42
            Pseudo Genes (incomplete)         :: 32 of 42
            Pseudo Genes (internal stop)      :: 5 of 42
            Pseudo Genes (multiple problems)  :: 3 of 42
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:24:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 124731
            Orig. end                         :: 150743
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAFFHJ010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26012
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26012
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26012
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16012](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16012
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            302..2182
                     /locus_tag="JN542_RS06205"
                     /old_locus_tag="JN542_06205"
     CDS             302..2182
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261813.1"
                     /locus_tag="JN542_RS06205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06205"
                     /product="SAG1250 family conjugative relaxase"
                     /protein_id="WP_017768984.1"
                     /transl_table=11
                     /translation="MVVTKHFAVHSTKYRKSLIKYILNPEKTKKLKLVSDFGMSNYLDF
                     PSYEELVEMYQANLTNNDRLYDSRNDRQQLKQTKIHAHHLIQSFSPEDKLTPEEINRIG
                     YETIKELTGGNFRFIVTTHTDKDHIHNHILINAIDLNSEKKLKWDYAQERNLRMISDRL
                     AKEAGAKIIPPNRYSHDRFETYRKTNHKFELKQRLYFLLENSKSFEDFMAKAPALNVEI
                     DFSRKHARFFMTDRDMRQVIRGHQLDKRQPYTEDFFREHFAKRAIEQRLDFLLPRARDL
                     SHLLDMAEQLNLTISPKKKHVTFTLKEGDRTISMENKKVSTKHLYDVQFLEDYFDKREI
                     TPEPDWANLFSDFKNYQEEQDQNKLPSEKLLTAYKDFKEKRDKIQEFEVILAGHQIDKL
                     VKDGIFIKMTYGVKKDGLVFIPNRNLDIHESDQDKTYHVFIRETAQFFIYNKENSDLNR
                     YMRGRELIRQLTHDSKHIPKRRRPTMASLKEKIAELNLLIELDINNKSYQEVKDELIKD
                     IAQLDLTITELQDKVAHLNKVAEVLLNLNNSDPENRRLARYDYAKMNLTAAVKIEGVEK
                     EIETSQNELSKSIDEYEYLVRRLEKFVKILNCVKSIDANIEYCSRKIMKT"
     gene            2274..3638
                     /locus_tag="JN542_RS06210"
                     /old_locus_tag="JN542_06210"
     CDS             2274..3638
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719507.1"
                     /locus_tag="JN542_RS06210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06210"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_017768983.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.8e-38, bitscore:
                     125.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRNLVLNIFLSSIILSFNNLPMQVKANENADVRYNILLKNPES
                     VDDIEMNFEKQGIKVTDKIPEINFLTVSTNKSIDEIRELNDSYIEEIVANNTLTVKPNI
                     TYLYGENVYTNNSFDFWSNQWDMQKSISTGTKFRHKSTGKATIGVIDSGITYDNPQIYS
                     NIISVKNFTADLDTGVVDEQNIIDKTGHATSVVGQISSNGEYKGIAPGMKIRMYRVFDE
                     GNAQDQWILKAIIQAAKDDVDVINLSLGEYLLENSTDEDDNTALVNIYQRAINYAYNQG
                     SVVVASVGDEGIDLDNQAELKDYLGSLNGKDYKQVDGFVRDIPAELDNIVTVGSVDDDD
                     YISSFSNRGSSVDIYATGGGTKALAEVGYENWVSKKLYEKDWVIVPTLEGKFTYAYGTS
                     IATPKVSAALGLIIEKYNLKDQPDEAIKILYDNSWLSKDDNNQEIRSLNITNFVQ"
     gene            3677..4360
                     /locus_tag="JN542_RS06215"
                     /old_locus_tag="JN542_06215"
     CDS             3677..4360
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /locus_tag="JN542_RS06215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06215"
                     /product="response regulator transcription factor"
                     /protein_id="WP_017768982.1"
                     /transl_table=11
                     /translation="MYKILAVDDDFEILKLMRTILEMRNYEVTTYQEVKVPLSINDFKG
                     FDLILLDVMMPNIDGLQICKKIRDEVDTPIVFVSARDSENDIVSGLNLGGDDYITKPFS
                     VHQLVAKVAAHLKREERHKTSKEKESVVRELLPITFYLQEKQVCINGDIIPLTRREYDI
                     LELLSRKTNKVYTREDIYEQVYDDEADALFRSISEYIYQIRGKFSPYGINPIRTIRGMG
                     YKWYD"
     gene            4353..5705
                     /locus_tag="JN542_RS06220"
                     /old_locus_tag="JN542_06220"
     CDS             4353..5705
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="JN542_RS06220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06220"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_017768981.1"
                     /transl_table=11
                     /translation="MTKKNYSIKQRSWKVVFEVIILTICNVVVILFLSAVLSELGLVTY
                     GTTGMDFPIQKEMTAEELSEVMKPYRYDFAIFSRMSEEVSQGHFVNNELHYYKSVIEKQ
                     KNLKVDLVHYEQFQTDDYFLVVRYSEVPEFSNQYFRKIPYNYLTITLFLLLFALSIIIC
                     LTRYIKEISANFRSIQNTSVQMGSRAFPLNDRYSQIDEFDAVLKTLHRKGNDLATLIEK
                     EKSEKKDFSFQVGALAHDIKTPLTVLKGNLELLEMTNLTEQQEDFISSMNHSINTFEKY
                     FNEMLSYSRLLIEDGESHKNIFLSEFLDDLLAEAEDIMVTQKVTFELTNSTSAKNFYGN
                     QLNLNRALINILANAARYANAEKKVILSVKDTADFLIFEVWNSGSAFTPEALSNANKLF
                     YTENFGRSSSHYGIGLSFAQKVAQKHEGRLVLTNPETGGAKVELYIKNKLL"
     gene            complement(5901..7180)
                     /locus_tag="JN542_RS06225"
                     /old_locus_tag="JN542_06225"
                     /pseudo=""
     CDS             complement(5901..7180)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937360.1"
                     /locus_tag="JN542_RS06225"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="JN542_06225"
                     /product="IS4 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFDQIKSHLLNSIDDIVSDANQFVRQPAKDFSRNSPLTMKTMLKS
                     LLALGGKSLAKELLDLDLPSLSLLSFNDVIRLNSKHLKGILEILLLKSPLLTLCQS"
     gene            7448..8140
                     /locus_tag="JN542_RS06230"
                     /old_locus_tag="JN542_06230"
     CDS             7448..8140
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006532171.1"
                     /locus_tag="JN542_RS06230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06230"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_017768979.1"
                     /transl_table=11
                     /translation="MQVKINNLSKNYGDRHVLKGVNFTIKAGSICGLLGVNGAGKSTLM
                     KIMFGLEKETSGEIFFDNRKRQVNEYNDRIGALIETPAIYMNLSAFDNLKTKALLYDIT
                     DDRIKEVLKKIGLENTGRKKAGKFSLGMKQRLGLGMAILTNPSLLILDEPTNGLDPDGI
                     KELLDLLKDLQRNGMTILISSHQLHEISKVADNIVILNEGYICYNELNNHDDNLEKIFF
                     NIVHGGLK"
     gene            8137..8856
                     /locus_tag="JN542_RS06235"
                     /old_locus_tag="JN542_06235"
     CDS             8137..8856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006532170.1"
                     /locus_tag="JN542_RS06235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06235"
                     /product="hypothetical protein"
                     /protein_id="WP_017768978.1"
                     /transl_table=11
                     /translation="MKNIIRSEFLKINNNSYRKLLVALPLLAALIAFLLVGPQILESFT
                     IYWWEALFLFALVGLLFLKDFKSEEKAGQFQNVTLGKLGYKIRVSKMILVAVQVFFSSA
                     FLMLIIKVMESYLYPNYMEVNTLHDSITLLFMLLSVVWNIALLYYLSDKLNPYLLVVGN
                     TFICLLIAPLIAQTKFWFIFPYTYHYKVAQTILHLRPSGDLEQSFGNLNHSTVLLCVLL
                     SAMLTLIICMLMYRKKE"
     gene            8859..9527
                     /locus_tag="JN542_RS06240"
                     /old_locus_tag="JN542_06240"
     CDS             8859..9527
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JN542_RS06240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JN542_06240"
                     /product="hypothetical protein"
                     /protein_id="WP_017768977.1"
                     /transl_table=11
                     /translation="MKIIQSEWLKIKMSYPSYLILGFSLIEIITILPYLIFVKSSKALE
                     AAIFFPMLAIAVIISLVAILICEQEEQANHFQILISEREGAKLWAAKIIILDLMLLLPT
                     IGVWSLLYLVFKQDSYLTVGLIYWLLSAFLNHFHLLLAFLLGNSGNLIVAFIECLLIIF
                     ATNKVFLEMHWLPIALPINMILEPVDGYLVNLSIFISWIVLLFLAQIYLLKYSKIKILK
                     "
     misc_feature    complement(9598..9613)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.88"
                     /tool="antismash"
     gene            9652..9816
                     /locus_tag="JN542_RS06245"
                     /old_locus_tag="JN542_06245"
     CDS             9652..9816
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="JN542_RS06245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06245"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_079267797.1"
                     /sec_met_domain="TIGR03731 (E-value: 8.1e-16, bitscore:
                     51.9, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNNDFNLDLVSTSKEKKQGASPRITSISLCTAGCITGRIMGCHK
                     TPTVSCNCH"
     CDS_motif       9652..9723
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MQNNDFNLDLVSTSKEKKQGASPR"
                     /locus_tag="JN542_RS06245_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9724..9816
                     /prepeptide="core"
                     /locus_tag="JN542_RS06245_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="21.80"
                     /molecular_weight="2964.5"
                     /monoisotopic_mass="2962.4"
                     /core_sequence="ITSISLCTAGCITGRIMGCHKTPTVSCNCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQNNDFNLDLVSTSKEKKQGASPR"
                     /leader_location="[9651:9723](+)"
                     /alternative_weights="2982.5"
                     /alternative_weights="3000.6"
                     /alternative_weights="3018.6"
     gene            10001..12994
                     /locus_tag="JN542_RS06250"
                     /old_locus_tag="JN542_06250"
     CDS             10001..12994
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="JN542_RS06250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06250"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_017768976.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.6e-83, bitscore:
                     275.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.8e-20,
                     bitscore: 67.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.9e-26, bitscore:
                     85.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNDKYFKTDSYLIRSSILETQTKNFVNNIDFLEHLKNDQIFLEQ
                     LFFANSSLYYQLLKYYQGNISNTKKVDKIAISVYRYYKRSHGRPTPLGLFSETSIGTFQ
                     ENNHMKLNENVNKIITLDAEWLMLLVYKFESEYYNSLSFTINNACYKKGDRIYQLYSLI
                     EDQEKISIRETSVYKIISKNCSRGYCNYRKLIEELVSVYGIESSNLAEDYILTLIKNHY
                     LLSDIQKDILCGSPREKLLDFISRNYIDIHIKTSLRNIFEMIDLYSKLPIGEGVALLEK
                     IYETMSSIVRSKSYLKIDLISNYSEFSFSTQIQEKFERFANFIALSTESTNKTHLDYYS
                     EAFLEKYGLEREVKLVELLDPCIGLGAPFGYNHPSNDFIMEEPPFEFYSEAEEQMYLDL
                     YTKAVSERRPIELSSIVNHYEKINSEKLSNIDGFDLFFNMVKKDGKTIFSLSNIIGSNT
                     LGGGSGRFAGLSGTLQNFHEKLLQHEDRIGDLDNISTCEILFLPENLRHRNIMNTVSNR
                     NFCLPISTDVSGKKILLEDIYIGLSSDLKFYARDIRSGEFIRFYSTNMYNLTLFCNELR
                     FLVEISIKNNIGKIPWEIIYKNFSYVPRLTFEDIIMAPAKWRVRVNDTMNSVNQIVKKY
                     GLPQTFYIEEGDSRILINLTKQLDYNSFENLLSSSFQNKTQLILTEVIGDDSPVVRNGK
                     STSSDLVIPFRNTNYLSNCSHGYKKIVETQDFELMDRERRQLPFQEWTYFKIYISEDRQ
                     DEFLIGYLTRLKNHILENEGKVFYLRYRDPKPHIRLRISGLSENIELYYSVLSIINEAI
                     KNCIVSTFSIDIYERELERYGGSLLMREIEDIFCVDSQICIEMINSSKLDSELSILDYA
                     VLVNYIYLKTLFIRDDSIIEFLEDVSPSNRSKNLNKTKHHYINMIKNYILKNNLQSNFP
                     IITELSILLHSIQFKINKFEKFRKTSIVDSIIHVHNNRLIGIDREQEKEIYNILRLVFQ
                     NEKFTKDK"
     aSDomain        10430..10687
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JN542_RS06250_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.90E-21"
                     /identifier="RREFam001.1"
                     /label="JN542_RS06250"
                     /locus_tag="JN542_RS06250"
                     /protein_end="229"
                     /protein_start="143"
                     /score="67.0"
                     /tool="antismash"
                     /translation="TINNACYKKGDRIYQLYSLIEDQEKISIRETSVYKIISKNCSRGY
                     CNYRKLIEELVSVYGIESSNLAEDYILTLIKNHYLLSDIQK"
     gene            12996..14774
                     /locus_tag="JN542_RS06255"
                     /old_locus_tag="JN542_06255"
     CDS             12996..14774
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015425980.1"
                     /locus_tag="JN542_RS06255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06255"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_225585635.1"
                     /transl_table=11
                     /translation="MDKITSKQLLSTVFTIPNTLKLIFRLEKKYATYLIVINVLIALFP
                     LGIFYVYQELINAILLQSNKVLQTLVIYFIVQSVSSIFVQINAFFLEKFNLNLSYSLSK
                     KLITKTSSLELADFENADTYNLVENLTQDSTYKPYQLFNAIISFFSSIISLLVCLFYIS
                     TWKTSIALFLLCIPLISLVTFLKIGQLEFLIQWNRVGAERKVWYYIYLLTHDFSFKEIK
                     LNNISDYLINKFSLIKEEFISQDSEISKKKNIFNAILDILLNFINCLVIIMLISAVRAG
                     EILLGNLISLIQALTRINTYSQSMIQSVYIIYNTSLFMEQLFNFFESEQYDQSNIYINN
                     TDISLKEVSEINLVDVSYCYPNSSINALSEISLSFKCGELVAIVGKNGSGKSTLVKLLC
                     GLYKPSQGEIVFNGISNKNLDLAFYQKHVSVLFQDFVKYELTLRENIALSNLEILNDTQ
                     AIKLALKKFSFEVDRDIDMQLGTWFQDGRQLSGGQWQKLALVRTFLKNASVYILDEPSS
                     ALDPVSEKEIFDKFIELSRDHVSIFISHNLKSAKKADKIIVMKDGKVDGVGNHETLLRT
                     NEHYKKMYYSEQYEEL"
     misc_feature    13020..13038
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 28.3"
                     /tool="antismash"
     gene            14774..16012
                     /locus_tag="JN542_RS06260"
                     /old_locus_tag="JN542_06260"
     CDS             14774..16012
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="JN542_RS06260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06260"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_017768974.1"
                     /sec_met_domain="LANC_like (E-value: 3.5e-55, bitscore:
                     181.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMDELLEDVSKITIAEYDFELDNIINSNNNYDVVTLSRGLPGYI
                     LLVSELNSNHVSSYEEKLTSYIEILVSILSERGVMTGSLYSGAAGIGISLLHLNENKYK
                     RLVESLDEYIEYFVSEFLPSIDTGNMSPTDYDIIEGVSGILVYISLHDRERLKDVQRKI
                     VNFLTSSFKEDIWNDIFYVTSQNQMSESESVLFPKGCLNLGVAHGLAGVGIALAYTMIK
                     GNFSCQIEETLRHIIDVYEQFETPSLYTWKDGLDIDELKQGYSNSKFLPNIDAWCYGSP
                     GISLLYMYCGVALNDEYLKNKAVEILKTSMERQSGIDSPILCHGYAGLLEICQFFKYVY
                     QTDEFDKYIYDFDKKITQYLQSKRNNELQIISQFGYLNGDVGVLLSMLHIYSKNVNTYW
                     QAGLLLFKDIIFE"
     gene            <16119..16394
                     /locus_tag="JN542_RS06265"
                     /old_locus_tag="JN542_06265"
                     /pseudo=""
     CDS             <16119..16394
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01168.1"
                     /locus_tag="JN542_RS06265"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; incomplete; partial in the middle
                     of a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="JN542_06265"
                     /product="YSIRK-type signal peptide-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="FSVRKYSIGVTSVLLVVCLFGATQKSVSADEIAAAIAFQEVIVNQ
                     NTASGNEIAEEFSQMDDVPLENEKINDSLEDVKTNIDVSNGKITYP"
     gene            16446..16670
                     /locus_tag="JN542_RS06270"
                     /old_locus_tag="JN542_06270"
     CDS             16446..16670
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JN542_RS06270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JN542_06270"
                     /product="hypothetical protein"
                     /protein_id="WP_017768972.1"
                     /transl_table=11
                     /translation="MHTESVTATSPESSKAEPADEELSKQSAITEDLNDTIPVEVVKQA
                     TNEVKPSKDGGFLMTIWLQLKTSLSKIMI"
     gene            16628..16864
                     /locus_tag="JN542_RS11070"
     CDS             16628..16864
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JN542_RS11070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_142350595.1"
                     /transl_table=11
                     /translation="MVAIEDFLEQNNDLKLSKGATSRAGKVIGDDYPASWKKRPDEFDT
                     WGYNKSTCTSFVAHRLHSVNKFEVPRAMGDAGQ"
     gene            <16910..>16996
                     /locus_tag="JN542_RS11275"
                     /pseudo=""
     CDS             16910..>16996
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017102.4"
                     /locus_tag="JN542_RS11275"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVGSVAWTTNGTFGHVSWVASVSGNTVTV"
     gene            17153..17512
                     /locus_tag="JN542_RS11075"
     CDS             17153..17512
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020049.4"
                     /locus_tag="JN542_RS11075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SH3 domain-containing protein"
                     /protein_id="WP_017768970.1"
                     /transl_table=11
                     /translation="MLLQPGTYRFTSRKGIKSEPKIYSTDIAYYDSGDTVNYDKTLVAD
                     NHEWISYVSYSGARRYIAINQLAKPVSPVVKGTTNIQNKNDQLGTFDVVISNVSGRQWI
                     SYIAYSGNRRYIAIS"
     gene            17649..17870
                     /locus_tag="JN542_RS06280"
                     /old_locus_tag="JN542_06280"
     CDS             17649..17870
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922422.1"
                     /locus_tag="JN542_RS06280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06280"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_017768969.1"
                     /transl_table=11
                     /translation="MYRRVKDLREDKDYSQDYLAKYLSCSQSAYSRLENGKRQLSIEYL
                     IKLSTLYHVSTDYLLGLTDYPYRLHHKK"
     misc_feature    17952..17967
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            18143..18283
                     /locus_tag="JN542_RS06285"
                     /old_locus_tag="JN542_06285"
     CDS             18143..18283
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069254.1"
                     /locus_tag="JN542_RS06285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06285"
                     /product="hypothetical protein"
                     /protein_id="WP_017768968.1"
                     /transl_table=11
                     /translation="MTKIIIGEDTSQVVIEGYKVTVKVTDKPLSLTDILDDLLGRKLEK
                     I"
     gene            18382..19956
                     /locus_tag="JN542_RS06290"
                     /old_locus_tag="JN542_06290"
     CDS             18382..19956
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158591.1"
                     /locus_tag="JN542_RS06290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06290"
                     /product="recombinase family protein"
                     /protein_id="WP_017768967.1"
                     /transl_table=11
                     /translation="MTQTCIYLRLSRDDGDNIESNSIVNQRSLLRDYAQKHDLIILEEF
                     VDDGISGLTFNRPDFNRMMTMVNEKRIDTIIVKDLSRFGRDYIETGKYIQRIFPSIGVR
                     FISVNDHYDSLTADTNETHLVLPIKSLINDSYCRDISMKVRSTQKAKRQNGEFIGAFAP
                     YGYRKDDNVRNHLVVDESARSIIEKIFTLKLEGYSSNRIATYLNKAGIATPLQYKKSCH
                     ENFKGFYGNSNQWNAKMVNRILVNRVYTGTLEQGKHTKLNYKSKQSLKVSPDDWVRVEN
                     THEGIVSKSTFEIANSLLLRDVKNGKGQPSLFTGLLFCKDCQSQMIQRKVRYKKIETIQ
                     YICSTYNKGKGCSRHSIKDDSLLEVISTLIAQHLEWKSYLIERIPHYLSQEPFLEIDFT
                     GLVTERKKYELLIQSLYMDLDDGLINELEYQEFQRHYRQKLKQVEETIALKKELAQELY
                     HKLQDREAWLKQLSELRDTDCLNRLTLVSLLDRINIGEDHEITLVFHDIKEMDILQQFS
                     QSETEAV"
     gene            19956..21572
                     /locus_tag="JN542_RS06295"
                     /old_locus_tag="JN542_06295"
     CDS             19956..21572
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768966.1"
                     /locus_tag="JN542_RS06295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06295"
                     /product="recombinase family protein"
                     /protein_id="WP_024375787.1"
                     /transl_table=11
                     /translation="MARTKNRYRTEETKTTQVTIYRTGIYIRLSKERTETWRNKSQSLE
                     TQESLARTFAKDKGLMVVKAYTDYEYSGTKFNRPAFQEMMEDIKKGHINCILIRDLSRL
                     GRDYIEMGRLIDKVFPFLGVRFISINDNLDTLNGLEEKKSFEVEIKNLVNDLYSKDISK
                     KVTASHIYHASRGYYIGSFAPYGYQLDKQEHGVKLMIDPLVKPILRIAFDILVQGKSIS
                     KVTAYLNKARVAVPTVYRRTGQLYRSEDDRTEWRNSTILRLIQSPVYQGHLVQRKSNKT
                     LTETDYIRFEYAHEAYITREEYDKIVTYLHSRRSIKKRLQPKRPNRYKGLIYAQGNSKQ
                     MYRYCRHFSNQKSDYDYYYFTDHVYDPQISEKQTVYISEIALDRIISELLQAEIERLGI
                     AEQLLSKLKTKKDDCIKVYYRQVRQHQQAILRLLEEISDLYASYSLVRTEKATYLTQKS
                     EKEAQIETLSQEIRHCEVAIGQLEEEHQKQISWVKSLTQCQGTETLTSELLQAIIERIE
                     VDVNKQVTITFRCQLGGAVNV"
     gene            21565..23001
                     /locus_tag="JN542_RS06300"
                     /old_locus_tag="JN542_06300"
     CDS             21565..23001
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041341.1"
                     /locus_tag="JN542_RS06300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06300"
                     /product="recombinase family protein"
                     /protein_id="WP_024410048.1"
                     /transl_table=11
                     /translation="MSKVALYLRLSVDEAGTDESISIVNQRYLLHHYLDNSSDFQNFQR
                     EEFVDDGFSGTTVNRPAFQRLMTKVKSGEIRHVIVKDLSRFMRDYLELGNYLENIFPFL
                     GVRFIALNDQYDSLASENNGVEIDVPFKNLLNEFYAKDVSEKIKSAMNSMKRSGKNMSW
                     LPPFGYLKDPEDRFKIIIDETVAPIVRRIFALYLDGNSYQTIARLLNEEQVITPAERKM
                     QISQARYAKSLRLTTEQKRNVWSSTTVGQILKNEAYKGTYLFNTRTYVRGKHVFRPKSE
                     WERIENNHEAIISSELFEQVVQLKGSKATKRKQHQIPKTSSVLTGLIRCEHCDHSLIGH
                     YNHQGYQYFSCRYCKGQGEKMKSCRVDRIEQAIKGKLGDEAVKPHQKVSKTLVLREIER
                     LKTEKLACFQDYKDSLLTREDYIAKKKEVDKSVQALEEQMKEANCVQLPTDKKLSKEIV
                     VAHVDKVVVDCLGFFTVIYK"
     gene            <23111..23455
                     /locus_tag="JN542_RS06305"
                     /old_locus_tag="JN542_06305"
                     /pseudo=""
     CDS             <23111..23455
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028182.1"
                     /locus_tag="JN542_RS06305"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06305"
                     /product="8-oxo-dGTP diphosphatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GHIEEGENFHDSVVREVFEETSLTIGNARLVGIKHWPDKEGHRYI
                     VFLYKATEFTGTIRSTEEGEVRWVEKSDLPQMDLAYDLLEILKVMDEPDLSEFFYTRKN
                     EDGEWDKNFR"
     gene            23649..24464
                     /locus_tag="JN542_RS06310"
                     /old_locus_tag="JN542_06310"
     CDS             23649..24464
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364850.1"
                     /locus_tag="JN542_RS06310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06310"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_301183206.1"
                     /transl_table=11
                     /translation="MMMKKYIMTGLVLLATMTLSACSGNATQEDTSLKDVQEKGKLIVA
                     LNPEFPPFEFRTLVDGKDTIVGADIELAKAIGQELGVEVEFSAMSFDNVLNNVQSGQSD
                     IAISGISATEERAKVYDFSIPYYTSTNKVIINKEDFAQYTSLDSLAEANIGAQKGSIQE
                     QIVKEQLPSSTVIALASNGELINQLKSQKVEAVIFEEPIAKAYVAKNDDLVILDTEIKS
                     SYSDAYAIALPKGSTALKEKVDSVITKLVESGQMDQFVQEAYELSIANN"
     gene            24636..25436
                     /locus_tag="JN542_RS06315"
                     /old_locus_tag="JN542_06315"
     CDS             24636..25436
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735814.1"
                     /locus_tag="JN542_RS06315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JN542_06315"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_014637883.1"
                     /transl_table=11
                     /translation="MKKILALAATVLAGLTLAACSSTSSQSALDKIKEKGTLVVATSPD
                     YAPFEFQALVDGKNEVVGADIMLAQKIADELGVKLEVSAMSFDNVLSSVQNGKADIAIA
                     GLSYSEERAKVFDFSESYYQISDVLLIKKDSANSLTSIDAMSGKTLAVQKGSTQEAYAQ
                     ENISQANLISLTLMGEAVNELKSGKVDAILMDSPVAAGYVSQNSDLAVASVEFPTIDEN
                     SKVIALPKGSTELKTAIDKVIAEVKASGEFDTFLEKAATYTSVE"
ORIGIN
        1 gagttggaaa ccctgaacaa ccgtatcggt cagagtggct gtaaaaattt ctctgcttat
       61 gctagaaaag ttctgctcaa tcccaacatg acctttctga ccattgacac cagtaactat
      121 gacgacttgg tatttgagtt gagacgaatc ggaaacaacc tcaatcaaat cgcacggacc
      181 gtcaaccaga ctcacatttt aacaccaagc gaccgtggat ttttggtaca aggcattggc
      241 caactcatca aggaagtgga gaaggacttc aacataaagt gtcagcagct gaaggagttt
      301 tatggtcgtc actaaacact ttgcggtgca tagcaccaag tatcgtaaga gcctcatcaa
      361 gtatattctc aatccagaaa agacgaagaa gctgaaactg gtctctgatt ttggcatgag
      421 caattacttg gactttccca gctatgagga attggtggag atgtatcagg caaacttgac
      481 caacaatgat cggctctatg attccagaaa cgaccgccag caactcaagc agaccaaaat
      541 ccatgcccac cacttgattc aatcattttc tcctgaagac aagctgacac cagaggaaat
      601 caatcgcatt ggttacgaga ctatcaagga gttgacaggg ggcaactttc gtttcatcgt
      661 cacgactcac acagacaagg atcatatcca taatcatatc ctgataaatg ccattgacct
      721 caattctgag aagaagctca agtgggacta tgcccaggag aggaatcttc gcatgatttc
      781 tgaccgtttg gccaaggaag caggagcaaa gattattccg cccaatcgct attcgcatga
      841 tcggtttgaa acctaccgca agaccaatca caagtttgaa ctcaagcagc ggctctattt
      901 tctcctggag aacagtaaga gctttgagga ctttatggcc aaggctcctg ctctaaacgt
      961 ggagatagat ttctctcgca agcacgccag atttttcatg accgaccgag acatgaggca
     1021 ggtcattcgt ggccatcagc tggataagcg acagccctac accgaggact ttttccgaga
     1081 gcattttgcc aaacgagcca ttgagcaacg actggatttc ctcttgccca gagcacgtga
     1141 cctatctcat cttttggaca tggcagagca gttaaacctg acaatctctc cgaagaaaaa
     1201 gcatgtgacc tttactttga aagagggcga ccgaaccatt tccatggaga ataaaaaggt
     1261 cagcacaaaa cacttgtacg atgtccagtt cttggaggat tattttgaca aaagagaaat
     1321 cacaccagaa cctgactggg ctaacctatt ctcagatttt aagaattatc aagaagagca
     1381 ggaccagaat aaacttccta gtgagaaact cttgacagcc tataaggatt tcaaggagaa
     1441 gcgagataag attcaggagt ttgaagttat tctagcaggc caccagattg acaagctggt
     1501 caaggacgga attttcatca agatgactta cggcgtcaaa aaagacggct tggtctttat
     1561 cccaaaccgt aacttggata ttcatgagag tgatcaggac aagacctacc atgtctttat
     1621 ccgagagacc gcccagtttt tcatttacaa taaagagaac tctgacctca accgctacat
     1681 gcgaggacgg gagttaatcc gccaactcac tcacgacagc aagcatatcc ctaaacgcag
     1741 acgcccgact atggccagtc tcaaagagaa aatagcagag cttaatcttc ttattgaatt
     1801 agacatcaac aacaaatctt accaggaagt caaagatgag ttaatcaagg acatcgccca
     1861 gctggatttg accattacgg agttgcagga taaggtcgct catctcaaca aagtagcaga
     1921 agtcctgctc aatcttaata actctgaccc agaaaacaga cggctagcca ggtatgatta
     1981 tgccaagatg aatctgactg cggctgtaaa aatagaaggg gttgagaaag aaattgaaac
     2041 ttctcaaaat gaactcagta aatccataga tgagtatgaa tatctagtga gaaggttgga
     2101 aaagtttgtt aaaatcttaa attgtgtaaa gtcaatcgat gctaatatag agtattgctc
     2161 tagaaaaatt atgaaaacat agaaaaattc aaataaaatg tgtaataatt attttgaaga
     2221 aattctgaaa tacagttggt ataatatagt caaaaaatat agaggttata atcatgaaaa
     2281 aaagaaattt agtattaaac atttttttgt cgtcaattat tctttcattt aataatttac
     2341 caatgcaagt gaaagctaat gaaaatgcag acgttaggta taatattcta ctaaaaaatc
     2401 ctgagtcggt tgatgatatt gaaatgaatt ttgaaaaaca aggaatcaag gttacagata
     2461 aaattcctga aataaacttt ttaactgtat ctactaataa aagtattgat gaaattagag
     2521 aactaaacga ttcgtatatt gaagaaattg tggctaataa tacgttaact gtaaaaccta
     2581 atataaccta tttatatggt gaaaatgttt atacaaataa tagctttgat ttctggtcaa
     2641 atcagtggga tatgcaaaaa agtatcagta cggggaccaa atttagacat aaatcaactg
     2701 gcaaggcaac aattggagtc atagactcag gtattacata tgataatcca caaatttatt
     2761 caaatattat ttcagtaaaa aactttacag cagatttaga tacgggtgta gttgatgagc
     2821 aaaatatcat cgataaaaca ggacatgcaa cgtcagttgt tggacaaatt tcatcaaatg
     2881 gtgaatataa aggcattgct ccaggaatga aaataaggat gtatcgtgta tttgatgagg
     2941 gaaacgctca agatcaatgg atattaaaag caattattca agcagcaaaa gatgatgttg
     3001 atgtcattaa tttaagttta ggagagtatc tgttagaaaa ctcaactgat gaagatgaca
     3061 atactgcctt agttaacatt tatcaaagag caatcaatta tgcttataat caaggttcgg
     3121 ttgttgttgc ctctgttgga gatgagggga ttgatttaga taatcaagct gaattgaaag
     3181 attatctagg aagtctaaat ggcaaagact ataagcaggt agacggtttt gtgagagata
     3241 tcccagcgga attagataac attgttacag ttggttccgt agatgatgat gattatattt
     3301 ccagtttttc aaataggggt agcagtgtag atatttatgc tactggaggt ggaactaagg
     3361 cattagcaga agttggttat gaaaactggg ttagtaaaaa gttatatgag aaagattggg
     3421 taattgttcc tacattagaa gggaaattca cttatgctta tgggacctct attgctactc
     3481 ctaaagtatc tgcggcatta ggactgatta ttgaaaagta taacttaaaa gatcaaccag
     3541 atgaagcaat taaaattcta tatgataata gctggttaag taaagatgac aataatcaag
     3601 aaattagatc gctgaatatt acgaattttg tgcaataata gtgtaaaata gaaatataat
     3661 attttgaggt atcaggatgt ataagatatt agctgtagat gatgattttg aaattttgaa
     3721 actgatgaga actattttag agatgagaaa ttatgaggta acaacctacc aagaggttaa
     3781 agttcctctt tctattaatg attttaaagg ttttgattta atacttcttg atgtcatgat
     3841 gcctaatatt gacggactac agatttgtaa aaaaattcgt gatgaagtag atacaccaat
     3901 tgtcttcgta agcgctagag atagtgaaaa tgatattgta tcaggtttaa atttaggcgg
     3961 agatgattat attactaaac cgtttagtgt ccatcaatta gtagcaaagg tcgctgctca
     4021 tctaaagaga gaggagaggc acaagacttc taaggagaaa gaaagcgttg ttagagaatt
     4081 gctccccatc actttctatc ttcaggaaaa acaagtttgt attaatggag acattatacc
     4141 tcttactcga agagagtatg atattttaga attgttatca cgtaaaacca ataaagttta
     4201 cacaagggaa gatatttatg agcaagtata tgatgacgag gctgatgcat tgtttaggtc
     4261 tatttctgaa tatatatatc aaataagagg gaaattttcg ccatatggaa ttaatccgat
     4321 tcgtacaata agaggcatgg gatacaagtg gtatgactaa aaagaactat tcgataaagc
     4381 agagaagttg gaaagttgtt tttgaagtta ttattttgac aatttgtaat gtagtagtga
     4441 ttttattttt atcagctgtg ctttccgagt taggtcttgt gacatatgga acgacaggaa
     4501 tggacttccc tatacagaaa gagatgacgg ctgaggaact tagtgaggtt atgaagcctt
     4561 atagatatga ctttgctatt tttagtagaa tgtcagaaga ggtcagtcaa ggtcatttcg
     4621 tcaataatga attgcattac tataaatcag tgatagaaaa gcagaaaaat ctcaaagtag
     4681 atttggtaca ttatgaacag tttcaaactg acgattattt tttagttgtc agatatagtg
     4741 aagtcccaga attttcaaat caatatttta gaaaaattcc ctataattac ctgactataa
     4801 ctttatttct cttacttttt gctctgtcaa ttattatttg tttaacgaga tacataaaag
     4861 agatttctgc aaattttaga tctattcaga atacgtctgt ccagatggga agtagagctt
     4921 tcccgctcaa tgatagatat tctcaaattg atgagtttga tgctgtttta aagactcttc
     4981 atagaaaggg caatgattta gcgacactta ttgaaaaaga aaaatcggag aagaaagatt
     5041 tttctttcca agttggtgct ctagctcatg atatcaaaac gccactaact gtattaaagg
     5101 gaaatctcga gttacttgaa atgactaatt tgacagagca acaagaagat tttatctctt
     5161 cgatgaacca tagcattaat acttttgaaa agtattttaa tgagatgtta agctattcga
     5221 ggcttttaat tgaagatgga gaatctcata aaaatatttt tttatcagaa tttttagatg
     5281 atttattggc cgaagctgag gatattatgg ttacccaaaa ggtgacgttc gaacttacta
     5341 attcgacatc agctaagaat ttttatggga atcaacttaa tttgaataga gcattaatta
     5401 atattttggc aaatgcagca cgttacgcta acgctgaaaa aaaggttata ttatcagtaa
     5461 aagatacagc agattttctt atttttgaag tttggaatag cggttcagca ttcacaccag
     5521 aggctcttag taacgctaat aaattatttt acactgaaaa ttttggtcga agtagtagtc
     5581 attatggaat tggattatca tttgcccaga aagttgccca aaaacatgaa ggaagattag
     5641 ttttgacaaa tcctgaaact ggaggagcaa aagtggaatt gtatattaag aacaaactct
     5701 tatgaagtaa aaattgaatt ttattatatc ataggaataa aggatagcat tcaaggagtc
     5761 aatgtcatta agttaacctc atccttcatc aaacaaccta ttcctacact cgtatattag
     5821 tgcatattct gggataggtt gtgcttttta tcgcattttg gccgcacaaa aggaaagttt
     5881 tttcccccat ttttcattaa ttatggaact ctataagtga aacttactgg actttggctt
     5941 tttatcattc ttggaaatgt tcgattgggt cgaacaatgg ataaatgctt ggctatgtag
     6001 gtgttcaatt tggaggaagc aagtatacct ctgagaaatt tttgacaggc ataaacagcg
     6061 tctgaaaagt tgattttata agcttttttc gcctttgatt gtttaatggt aacatgtgag
     6121 atgagccatt tacaaaagtt aacattgata aaacgtgcat agatttcttg gagaatccct
     6181 tccttctttt tggcatgaaa atgagtcaac cccacactgt atttaaggtc acgaaaactg
     6241 gtctctatgc tccagctgct ggcatagagg tcttttaatt tttccacggg attatctgta
     6301 tttgtaacta aggtttcata gcaaccaggt tggatttcca gtcgtaccat acgaaatgtt
     6361 agctcataaa agctgatggg ttccgctttt cgactagagc tcggtaagaa atcaaaaggg
     6421 tagtgatgcg ttaaatagtg atattggttg ggaaagtctc gatagttttg cttcatctcc
     6481 tgggtttgtt tccgacagag tttgaggttg aaatgttcat caaaacaagg cgtgtcaggc
     6541 aggttcaaac ctgatttgat ggaggcattt ccatcccgaa ttcggatgac atacaaccaa
     6601 tttttctctt ggcaatggac catgacattg taagattcat agcctctatc cacgatgaca
     6661 agtgctcgtg cgaaagggag aattctccat catgtcaatg attcatcatt atcgaccttg
     6721 tcttgaatcc gcaggtcacg ataaacagcg ttttctaaat cgtaaagtgc attgatatga
     6781 gtcaaattgt aaggcgtacg atttgccccc gtttggatac aggtcgtctt atcaaagcga
     6841 tttctaggca aaatgacatc actgccatcc acagctaaga ttggcatagg gttaacagtg
     6901 gggattttag cagtaaaatc tctaaaatgc ctttcaaatg cttggaattt aatctgataa
     6961 cgtcgttgaa cgaaagcaga ctgagagacg gcaagtccag atccagcagt tctttagcta
     7021 aactcttgcc acccaaggca aggagagatt tcaacatcgt tttcatggtc aatgggctgt
     7081 ttcgactgaa atcttttgct ggttgacgga caaactggtt ggcatctgaa acgatgtcat
     7141 caatactatt aagcaaatga cttttaattt ggtcaaacat gattttctcc ttttattttt
     7201 agtctaacat agaaaaaaat cccctgccac tcaaaatttg gagtagtagg ggatttaact
     7261 taatgacatt gttcaaggag tgactatctt tttttatatg attttgagat agttgctcta
     7321 actgaaaacg ccttaggaga tttcttccta taagaaaaat gactcgtttt cataaaagtt
     7381 ttgactctga acaaaatctg aacaagaagt aatatgatgt ttgtataaag taaggaggaa
     7441 actatttatg caagtaaaaa tcaataatct atccaaaaat tatggagata gacatgtact
     7501 aaagggtgtt aatttcacaa ttaaagctgg cagtatctgt ggcttattag gtgtgaatgg
     7561 agcaggaaaa tcaacactaa tgaaaattat gtttggttta gagaaggaaa caagtggaga
     7621 gatctttttt gataatcgta aacgtcaagt aaatgaatat aatgatagaa taggagcttt
     7681 aatagaaaca cctgctatct atatgaatct ttcagcattt gataatttaa aaaccaaagc
     7741 attgctgtat gatattacag atgatcgaat taaagaagtt ttaaaaaaga ttgggctaga
     7801 aaatactgga agaaagaaag caggtaagtt ttctttagga atgaagcaac gcttgggctt
     7861 aggaatggct attttgacga acccgagttt acttattctt gatgaaccaa caaatgggtt
     7921 agatccagat ggaattaagg aactattaga tttattgaag gatttgcaga ggaatgggat
     7981 gacaattctt atctcaagtc atcaattgca tgaaatcagt aaggtggctg ataatattgt
     8041 aatcttaaat gagggctata tttgctataa cgaattaaat aatcacgatg ataacttaga
     8101 aaagattttc tttaacattg tccatggagg tttgaaatga aaaatattat ccgatcagag
     8161 tttttgaaaa taaataataa tagttatagg aaactattgg tagccctccc cttgttagca
     8221 gcattgattg ctttcttatt agttggacca cagattttag aaagttttac aatttattgg
     8281 tgggaggcac tatttctctt tgctttagtg gggttacttt ttcttaagga ttttaaaagc
     8341 gaagagaagg caggtcaatt tcaaaatgtt actttaggaa aattaggata taaaattcgg
     8401 gtatctaaaa tgattttagt agcagttcaa gtcttttttt caagtgcatt cttgatgctt
     8461 atcataaaag taatggaaag ctatttatat ccgaattata tggaggttaa tactttacat
     8521 gattcaataa cattattgtt tatgctatta agtgtggttt ggaatatagc tcttctgtat
     8581 tatttatcag ataagttaaa cccttacctg cttgtagttg ggaacacttt tatttgcctt
     8641 ttgattgcac cattgattgc acagacaaag ttctggttta tttttcctta tacctatcat
     8701 tacaaggtgg cacagactat actacattta cgaccgtctg gtgacttaga acaaagtttt
     8761 ggaaatctaa atcattccac agttttattg tgtgtactct tgtcagcaat gttaacgctt
     8821 attatttgta tgttaatgta tcgaaagaag gaatgaatat gaaaataatt caaagtgagt
     8881 ggctgaaaat taaaatgtca tatccaagct atcttatatt aggtttttcg ttaattgaaa
     8941 taatcacgat tttgccatat ttaatatttg tgaaaagtag taaagcttta gaagctgcta
     9001 tcttctttcc aatgctagct attgcagtaa tcattagctt agtagctatt ttgatttgtg
     9061 aacaagaaga gcaggctaat cactttcaaa tattgattag tgaacgggaa ggagctaagt
     9121 tatgggcggc taagatcata attttagatt taatgctttt actaccaaca attggggtat
     9181 ggagcttatt atacttagtt ttcaagcaag attcatattt aacagttgga ttaatctatt
     9241 ggttattaag tgctttccta aatcattttc acttattgtt agcctttctt ttaggaaata
     9301 gtgggaattt gattgtagcg tttattgagt gtttacttat tatctttgca acaaataagg
     9361 tatttttaga gatgcactgg ttaccaatag cactaccaat taatatgatt ttagaacctg
     9421 tagatgggta tttagtaaac ctatctatct ttatcagttg gatagttttg ctatttttag
     9481 ctcaaatata tttactaaaa tactcaaaaa ttaaaatatt gaagtaatta atcattctat
     9541 tcaaaaaaat atatatagaa aaattttttc tgaacaaatt ctgaaatacg agtattatag
     9601 tacaggtgtt cgaacaaata aaataaattt caaaaattgg aggaaattat aatgcaaaat
     9661 aatgatttta atcttgacct agtgtcaact tcaaaagaaa aaaaacaggg tgcttcacca
     9721 cgtattacta gtatctcatt atgtacagct ggttgtatta caggtagaat tatgggatgt
     9781 cataagacac caacagtttc atgtaactgt cactaattaa ctttttattt gggtagcagc
     9841 tatttagtca tgctaccttt atttttatca gttttgttcg atattgaata aagctgataa
     9901 aagtaaaata aatgctgtag aatgtaattt atttaaaatc tataatcact aatctataat
     9961 cactaaatga agttatgaaa taccaaagga gataggaaaa atggtgaatg acaaatattt
    10021 taagacagat tcttatttaa ttcgaagttc aattttagaa actcagacta aaaattttgt
    10081 gaataatatt gactttttag aacatttgaa gaatgatcaa atatttttag agcaattatt
    10141 ttttgccaat tcgtctctct actatcaact actaaaatac tatcaaggta acatttctaa
    10201 tactaaaaaa gtagataaaa ttgcaatctc agtatatcga tattataaac gttctcatgg
    10261 aaggccaact ccattgggat tattcagcga aacctctata gggacatttc aagagaataa
    10321 tcatatgaaa cttaatgaaa atgtaaataa aattattaca ttggatgctg aatggttaat
    10381 gttattagtc tataaatttg aatctgagta ctacaactca ctaagtttta ctattaataa
    10441 tgcttgttat aaaaaaggtg ataggattta tcaactttac tcactcattg aagatcaaga
    10501 aaaaattagt attagggaaa cttcagtata taaaataatt tcaaaaaatt gtagtcgggg
    10561 ttactgtaat tatcgaaaac ttattgaaga gttagttagt gtatatggaa tagaaagttc
    10621 taatcttgcc gaggactata ttttaacttt aataaaaaat cattaccttt tatcggatat
    10681 tcaaaaagat atactatgcg gttcaccaag agaaaaattg ttagatttta tttcacgtaa
    10741 ttatatagac attcatataa aaacttcatt gcgtaatatt tttgaaatga ttgatttata
    10801 ctcgaaactt ccaattggag aaggggttgc actcttagaa aaaatttatg aaacaatgtc
    10861 atcaatcgta agaagtaaat cataccttaa aattgatctg atatctaact attctgagtt
    10921 ttcattctca actcaaatac aagagaagtt cgaaagattt gcaaacttca tagctctttc
    10981 aacagaatct actaataaaa cacatcttga ttactattca gaagcttttt tagaaaaata
    11041 tggacttgaa agagaagtca aattagttga actattggat ccctgtattg gtttaggagc
    11101 tccatttggt tataatcatc ctagtaatga tttcataatg gaggaaccac cttttgaatt
    11161 ttactccgaa gcggaagaac aaatgtatct ggatctatat actaaagcag ttagtgagcg
    11221 aagacctatt gaactttcat caatagtaaa tcattatgaa aaaattaatt cagaaaagtt
    11281 atctaatata gacggttttg atcttttttt taatatggta aaaaaggatg gtaaaacaat
    11341 ctttagtctt agtaatatta ttggttcaaa tacattaggt ggcggttccg gtcgttttgc
    11401 tggcttgagt ggcactctac agaattttca tgagaaacta ttacaacatg aagatagaat
    11461 tggggactta gataatatta gtacttgcga aattttattt ttaccagaga acttgaggca
    11521 tagaaatatt atgaatactg tttcaaatag aaatttctgc cttcctatat ctacagatgt
    11581 ttctggtaag aaaattttat tagaagatat ttatatagga cttagctcag atttgaaatt
    11641 ttacgctagg gatataagaa gtggagagtt tatcagattt tattctacca atatgtacaa
    11701 tttgacgtta ttttgtaatg agctaagatt tttagttgaa atttcaataa aaaataatat
    11761 tggaaaaata ccttgggaaa taatttataa aaattttagt tatgtaccta gattgacttt
    11821 tgaagatatt atcatggctc ctgcaaagtg gcgtgttcgt gttaatgata ctatgaactc
    11881 agttaatcaa attgtaaaaa aatatggtct acctcaaact ttctatatcg aagaaggaga
    11941 tagtagaatc cttatcaact taactaaaca attggattac aatagttttg aaaatctgtt
    12001 atctagcagc ttccaaaata aaactcagtt aattttaact gaggtcatag gagatgatag
    12061 tccggtagtg agaaacggga aatcaacatc gtctgattta gtgattcctt ttagaaatac
    12121 aaattatttg agtaattgtt cgcacggtta taaaaaaatt gtggaaactc aggattttga
    12181 attgatggat cgagaacgta ggcaattacc atttcaagag tggacgtact ttaaaattta
    12241 tatatcagaa gataggcagg atgagtttct aataggttat ttaacgagac ttaagaatca
    12301 tattttagaa aatgaaggta aggtctttta cttaaggtat agggatccca aacctcatat
    12361 caggcttaga atatcaggat tatcagagaa tatagaattg tattatagtg tactatcaat
    12421 tataaatgaa gcaataaaaa actgtattgt ttctacattt tcaattgata tctacgagag
    12481 agagcttgaa agatatggtg gtagtttact tatgagagaa attgaagata tcttctgtgt
    12541 agattctcaa atttgtattg aaatgattaa ttcctctaaa cttgactccg agctatctat
    12601 tttagattat gcggttttgg ttaattacat atatttaaaa actctcttta taagagatga
    12661 ctcaattatt gaattcctag aggatgtttc cccatcaaat agatcaaaga atttgaataa
    12721 aacaaagcat cactatataa atatgataaa aaattatatt ttgaagaata atctccaatc
    12781 aaattttcct ataataactg aactaagtat attgcttcac tctatccagt tcaaaataaa
    12841 taagttcgaa aaattccgaa aaacatctat tgtggatagt ataatccatg ttcataataa
    12901 tagattaata ggtattgatc gagaacaaga aaaagagata tataatattt taagattggt
    12961 ctttcaaaat gaaaaattta caaaggataa gtaatatgga taaaattacc tccaaacaat
    13021 tattgtctac agtattcacg attccaaata cattaaagtt aatttttcga ctagaaaaga
    13081 aatatgccac atatttaatt gttatcaatg tattaatagc tctatttcca ttaggcatat
    13141 tttacgttta tcaagagtta ataaatgcaa ttttgttgca gtctaataaa gttttacaaa
    13201 cattagtcat atattttata gtgcaaagtg ttagttctat ttttgtacaa attaatgcat
    13261 ttttcctaga gaagttcaat ttaaatttat cttatagctt aagtaaaaaa ttgattacaa
    13321 aaacatcttc actagaattg gctgattttg aaaatgctga cacatataac ctagttgaga
    13381 atctaacaca ggatagtaca tataaaccat atcaattatt caatgctatc ataagtttct
    13441 tttcctctat tatttcttta ctagtttgtt tattttatat aagtacatgg aaaactagta
    13501 ttgcactttt tttgttgtgc atacctctta tttctttagt cactttttta aaaattggac
    13561 aactagaatt tttaatccaa tggaatcgtg ttggtgctga gagaaaagtc tggtattata
    13621 tctacttatt aacacatgac ttttcattta aggaaattaa attaaataac atcagtgact
    13681 atttaattaa taagtttagt ttaataaaag aagaatttat ttctcaagat tcggaaattt
    13741 caaagaaaaa gaatattttt aatgctattt tagacatttt gctgaatttt ataaattgtt
    13801 tagttatcat aatgttaatt tctgctgtta gagcagggga gattttatta ggaaatctaa
    13861 taagtcttat tcaggctctt acaagaatca atacgtactc tcaatctatg atacagagcg
    13921 tatatataat atataatact agcttattca tggagcaatt atttaacttt tttgagtcag
    13981 agcaatatga tcaatcaaat atatatataa ataacacaga tatttcacta aaggaagtat
    14041 cagaaatcaa tttagtggat gttagttatt gttatcccaa tagttctatt aatgcattat
    14101 cagaaatcag cctaagtttt aaatgtggtg aacttgtcgc tattgtgggg aaaaatggtt
    14161 cgggtaaaag tacattagta aaattattat gtgggcttta taagccaagt caaggtgaga
    14221 tagtatttaa tggtatctcg aataaaaatt tagatttagc cttttatcaa aagcatgtat
    14281 cagttctttt tcaagacttt gttaaatatg aattaacttt gagagaaaat atagcattaa
    14341 gtaatttaga aattttaaac gatacacaag ctattaagtt agctttaaag aaattttctt
    14401 ttgaagtgga tcgggatatt gatatgcaat tggggacttg gtttcaagat gggcgccaat
    14461 tgtctggtgg tcaatggcaa aaattagcct tagtaaggac tttcttaaaa aatgcttctg
    14521 tttatatttt agatgaacca agttcagcac tagacccagt atctgaaaaa gaaatattcg
    14581 ataaattcat agagctttct cgtgaccatg tatctatttt tatttcacac aatttaaagt
    14641 cagctaaaaa agcagataag attattgtaa tgaaagatgg aaaagttgat ggagtgggta
    14701 atcatgaaac tttattaagg acaaatgagc actataaaaa aatgtactat tcagaacaat
    14761 atgaggaatt atgatgaaaa tggatgaatt acttgaagat gtctcaaaaa taacaatagc
    14821 tgaatatgat tttgaacttg ataacattat aaatagtaat aataactatg atgttgtgac
    14881 tttatcacgt ggacttccag gttatatatt actagtatcg gaactgaaca gtaatcacgt
    14941 aagttcatat gaagaaaaac tgacttctta tattgaaatt ctagtttcaa tattatcaga
    15001 aagaggtgtt atgacaggct ctctgtattc gggtgctgct ggaattggga ttagcttatt
    15061 acatttaaat gaaaataagt ataaaagatt agtggaaagt ttagatgaat atatcgaata
    15121 tttcgttagt gaatttttac cttcgataga tacgggaaat atgtccccaa cagactatga
    15181 tattatagag ggagtatctg gtatcttagt ttatatctcg cttcatgata gagaaaggtt
    15241 aaaagatgtt caaagaaaaa ttgtaaattt tttgactagt tcattcaaag aggatatatg
    15301 gaacgatatt ttttatgtca cttctcaaaa tcaaatgtct gaatcggaga gcgtactatt
    15361 tcccaaaggt tgcttaaatt taggggtagc acatggctta gcgggagttg gaattgcttt
    15421 agcttacaca atgataaaag gaaactttag ttgtcaaatt gaagaaacct tgcgacatat
    15481 cattgatgta tatgaacaat ttgaaacacc tagtttgtat acatggaagg atggattaga
    15541 tattgatgaa ttaaaacaag gatattctaa ttctaaattc ttaccaaata ttgatgcatg
    15601 gtgctatggt agtccaggca tatctctatt atatatgtat tgcggagttg cattaaatga
    15661 tgagtatctc aagaataaag cagtcgaaat tttaaaaact tcaatggaaa gacaatctgg
    15721 aatagattct cctattttat gtcatggtta tgctggatta ctagaaatat gtcaattttt
    15781 caagtatgta tatcaaacag atgaatttga taaatatatt tatgattttg ataaaaaaat
    15841 tacccaatac ctgcagtcca aaaggaataa cgaattacaa ataatttcac agtttggcta
    15901 tttaaatggc gatgtgggtg ttttattatc tatgttgcac atatattcaa agaatgtgaa
    15961 cacctattgg caggcaggac tacttttatt taaggatata atttttgaat aaacggttcg
    16021 atattctgaa caaaccctga acttttaact ttacaatatc aagtgtaaag gagtacaaat
    16081 tcatgaaaaa agaattttga tcaactgagc gtcaacgttt ttctgtacgc aagtattcaa
    16141 ttggtgttac ttcagtgttg cttgtggtat gtttatttgg ggcaactcag aagagtgtat
    16201 ctgcagatga aatagcagct gcaatcgctt ttcaagaagt tatagtcaat caaaatactg
    16261 cttctgggaa tgaaatagct gaggaattct ctcaaatgga tgatgtacca ttagaaaacg
    16321 aaaaaattaa tgatagtctt gaagacgtca aaactaatat agatgtttct aatgggaaaa
    16381 taacttatcc ctaaaatatt gacgtaaaaa aacaagctga atcaaatata ctagatgagt
    16441 tagcggtgca tacagaaagt gtaacggcta cttcgccaga atcaagcaaa gcagagcctg
    16501 cagatgaaga attatctaaa cagtcagcaa ttacagagga cttgaatgat acaatcccgg
    16561 tagaggttgt aaaacaagct actaatgaag ttaaacctag caaagatggt ggatttttga
    16621 tgacgatttg gttgcaattg aagacttcct tgagcaaaat aatgatttga aattatctaa
    16681 aggagctact tctagagcag ggaaagtaat aggtgatgat tatccagcta gttggaaaaa
    16741 gagaccagat gagtttgata cttggggata caataaatca acatgtactt catttgtagc
    16801 gcataggtta catagcgtaa acaaatttga agttccaaga gcaatgggag atgctggaca
    16861 gtaggggaat acagcccgtc gattaggcta ttgagtagat aatactccag ctgttggctc
    16921 agtagcttgg acaacaaatg gaacatttgg gcatgtttct tgggttgcct cagtatcagg
    16981 aaatacagta acagtagaag aatataactg gaactgggat tatgcttatc acacgcgaat
    17041 acaaccgatt tcagcatata ctggctttgt tcattttaaa gatttaacta gcagtaattc
    17101 ttctgatgca tcaggcggta attcttcagg aggacagact aatctaggaa ctatgttact
    17161 tcagcctgga acatatagat ttactagccg taaaggcatt aaatcagaac ctaaaatcta
    17221 tagtaccgac atagcttatt atgacagtgg agatacagtc aattatgata aaacattagt
    17281 agccgataat catgagtgga tatcatatgt ttcatattct ggggcacgca gatatatcgc
    17341 tattaaccag ttagccaaac cagtttcgcc tgttgtcaaa ggaacaacta acattcaaaa
    17401 caaaaatgat cagttaggta cttttgatgt tgtaatttca aacgtttcag gacgccaatg
    17461 gatttcgtac attgcttata gtggtaatag aagatatatt gcgattagtt aactgaattg
    17521 aagggaatag cactttgtga gtaattcatt ttagtgctat ccctcttttt tacaataatt
    17581 tatgccaatc tggcataaat tataagattc gttcaaagct tgactataat ggtgttagga
    17641 gtggacggat gtataggcgt gttaaggatt taagagagga taaagattac tctcaagact
    17701 atcttgcgaa gtatttatcc tgtagtcaat cagcttattc aaggcttgaa aatggtaaaa
    17761 gacaattatc aatcgaatac ttaattaaac tatcaacttt atatcatgtt agtaccgatt
    17821 atttgcttgg tttaacagat tatccttatc gccttcatca taaaaaatag tctctccttg
    17881 tttgttcatt gacaactgaa tagaccaagg tgggactttc ttatttgtcg agcagtttag
    17941 cttgattcgc catgatatga gcgaacaaaa tcagctataa aatagaatgg tattctatct
    18001 gccaagacac aaattaagga taatgatact tctgcacgtt cgggctgcca gcgataaagg
    18061 ccagcgggtg taactcccat gaatgaccta accagtcatt cccgctgagg tcattatttt
    18121 aaattttaag gaataatata gtatgacaaa aataataata ggtgaggaca catcgcaggt
    18181 tgtcattgaa ggctacaaag taacggtaaa ggttaccgat aagccattga gcctaacgga
    18241 tattttagat gatttacttg gtagaaagtt agaaaaaata taaactttta gcggacaagt
    18301 aacagtaaat tatgtaaaat agaatagtag aacttcaatc cttgattgat ccgcacctaa
    18361 tattcgatta aggagaagac aatgacacaa acctgtattt atttacgcct atcacgagac
    18421 gatggagata atattgaaag taactccatt gtcaatcagc gttcactttt acgagactat
    18481 gcccaaaagc atgaccttat catcttagaa gaatttgtag atgatggcat tagtggccta
    18541 acctttaatc gtcctgattt caaccgtatg atgacgatgg ttaatgagaa aaggatagat
    18601 actattatcg tcaaagacct gtctcggttt gggcgagact atattgagac tgggaagtat
    18661 attcaaagga ttttcccttc tattggtgtt aggtttatct cggtcaatga tcattatgat
    18721 agtttgactg ctgataccaa tgaaacacat cttgtcctgc cgattaaaag ccttatcaat
    18781 gatagctact gtcgggatat ttctatgaaa gtccgtagca cacagaaggc taagcgtcag
    18841 aacggagaat ttataggagc ttttgcccct tacggttatc gtaaagacga taacgtgagg
    18901 aaccacctag tagtggatga gagtgctcgt tcaatcattg aaaaaatctt tacactcaag
    18961 ttagaaggat attcttccaa taggattgcc acttatctca ataaagctgg cattgcaacc
    19021 ccactccaat ataagaaatc ttgtcacgaa aatttcaagg gattttatgg taattctaat
    19081 cagtggaatg ccaaaatggt taatcgtatt ctggtcaata gagtttatac agggacttta
    19141 gaacagggaa aacatacgaa actgaattac aaatcgaaac agtctctaaa ggttagtcca
    19201 gatgactggg tgcgggtaga gaacacacac gaaggtattg tatctaaaag cacctttgag
    19261 attgccaata gcttattact tagagatgtc aaaaatggaa aagggcagcc ttctttattt
    19321 acaggattac tcttttgtaa agactgtcaa tctcagatga tacagcgaaa agtccgttac
    19381 aagaaaatag agaccattca gtacatctgt agtacataca acaagggaaa aggttgtagt
    19441 cgtcattcta ttaaggacga cagcctactg gaagtcattt caaccttgat agctcaacac
    19501 ctggagtgga agtcctatct gattgaacgt atccctcatt atctttcaca agaacctttt
    19561 cttgaaattg actttacagg acttgtgacc gaacgaaaga agtatgagct attaatccaa
    19621 tccctgtata tggacctaga tgatggtctt atcaatgagt tggagtatca ggaatttcag
    19681 agacattatc gccaaaagct gaagcaggtt gaagaaacca tcgctcttaa aaaagaatta
    19741 gctcaggaac tctatcataa actccaagat agggaagctt ggttgaagca attaagtgag
    19801 ttgagagaca cagactgctt aaaccgcttg acattggttt ccctcttaga tcggattaat
    19861 attggagaag accacgagat tacgctggtc tttcatgata taaaagagat ggatattctc
    19921 caacagtttt ctcaatcgga aacggaggcg gtttgatggc tcgcacgaag aatcgctatc
    19981 gtacagaaga aacaaagact actcaggtta caatctatcg aactggtatt tacattagat
    20041 tatctaagga aagaacagaa acttggagaa ataaatcaca gtcattagag acacaagaaa
    20101 gcttagcgag aacattcgcc aaagataagg gcttaatggt tgttaaggca tatactgatt
    20161 atgagtattc aggcacgaag tttaaccgcc ctgcctttca agaaatgatg gaggacatta
    20221 aaaaaggtca tatcaattgt attctgattc gtgacttatc acgcctgggt agagattata
    20281 tcgaaatggg tcgtcttatt gataaagttt tccccttctt gggtgttcgt ttcatctcta
    20341 tcaatgataa ccttgatacc cttaacggac ttgaagaaaa gaagtcgttt gaggtagaaa
    20401 ttaagaattt ggttaacgac ctttattcta aagatatttc aaagaaagtg actgcgagtc
    20461 atatttatca tgctagccgt ggctactata ttggaagttt tgctccgtat gggtatcagt
    20521 tggacaaaca agagcatggt gtcaaactga tgatagaccc tcttgtaaag ccgattttaa
    20581 gaatagcttt cgacatttta gttcagggaa aatccattag taaagtaacg gcatatctca
    20641 ataaagctag agttgcagtt ccaaccgtat ataggcgaac tggacaacta tatcgtagtg
    20701 aagatgatcg aacagagtgg agaaattcga ctatccttcg tttaatccaa agtcctgttt
    20761 atcagggaca tcttgtgcag cgtaaatcca ataaaactct tacggagacg gattatattc
    20821 gatttgaata cgctcatgaa gcttatatca ctcgagaaga atatgataaa atcgttacct
    20881 atcttcacag cagacggagt attaaaaaaa ggctacagcc gaagaggcct aatcgataca
    20941 agggattgat ttacgctcaa ggaaattcta agcaaatgta tcgctattgt cgtcactttt
    21001 caaatcagaa atctgactat gattattatt acttcacgga ccatgtctat gaccctcaaa
    21061 tatctgaaaa acagacagtt tatattagtg agatagcttt agatagaata atctcagagt
    21121 tgcttcaagc agaaatcgaa cgtttaggaa tagctgagca gctactgtct aagttgaaaa
    21181 caaaaaaaga tgattgtatt aaggtttatt ataggcaagt aaggcaacac caacaagcta
    21241 tcttgcgatt actagaagaa ataagtgact tatatgcttc atatagtttg gtacggactg
    21301 aaaaagcaac ctatctcact caaaaatctg aaaaggaagc tcaaattgag acactttcgc
    21361 aggaaataag acattgtgag gtggctattg ggcaactgga agaagaacat cagaagcaga
    21421 taagttgggt aaaatcgcta actcaatgcc aaggaacaga gactctaacc tcggaactat
    21481 tacaggcaat tatcgaacgc atcgaagttg acgtaaataa acaagtaacg attacttttc
    21541 gctgtcagct gggaggtgca gtcaatgtct aaagtagctt tatatcttag attatctgtc
    21601 gatgaggctg gaacggatga gagtatttcc attgtcaatc aaagatactt gcttcatcat
    21661 tatctagata attcatctga ctttcaaaac tttcagcgag aagaatttgt ggatgacggt
    21721 ttctcaggga caaccgtcaa tcgtcctgct tttcaacgat tgatgacaaa ggtaaaatct
    21781 ggcgagattc gtcatgttat tgttaaagac ctctcacgat ttatgcgtga ttatctggag
    21841 ttaggaaact acctggaaaa tatattcccc tttctaggag tgaggttcat tgctctaaat
    21901 gaccaatatg atagcctggc atcagagaat aatggtgttg agattgacgt tccctttaag
    21961 aatttgctta atgaatttta tgctaaggat gtttctgaaa agatcaagag tgcgatgaac
    22021 agcatgaaac gctcgggcaa aaacatgagc tggttgccgc cgtttggtta tctcaaggat
    22081 ccagaggacc gtttcaagat tattattgac gagacagttg caccaattgt tcgacggatt
    22141 ttcgccttgt accttgatgg taatagttac caaacaattg ctcgactcct gaatgaagaa
    22201 caagtcatta ctccagcaga acgaaagatg caaatcagtc aggcacgtta cgcaaagtca
    22261 ctccgtttaa caactgagca aaaacgaaat gtttggagta gcactaccgt tggtcaaatt
    22321 ttaaagaatg aagcctataa gggaacttat ctttttaata ctcggacgta tgtaaggggg
    22381 aagcatgttt tcagaccaaa atcagagtgg gagcggattg agaacaatca cgaagcgatt
    22441 atttcatcag aactatttga acaagttgtc caattaaaag gatcaaaagc cactaaaaga
    22501 aaacagcatc agatacctaa aacatcatct gtattgacag gtctgattcg ttgtgagcat
    22561 tgtgatcatt ctttgattgg acattacaac catcaaggtt accaatattt ttcctgtcgt
    22621 tattgtaagg ggcagggaga aaaaatgaag tcttgtcgag tggataggat tgaacaagca
    22681 atcaaaggga aactaggaga tgaagcagta aaacctcatc aaaaggtatc taagaccctt
    22741 gttcttcgtg aaattgaacg tttgaagaca gaaaaacttg cctgctttca ggactacaag
    22801 gatagcctgt tgaccagaga agattatatt gccaagaaaa aggaagtgga taaatctgtt
    22861 caggctttgg aagaacagat gaaagaagcg aactgtgttc agttaccaac tgacaagaag
    22921 ttaagcaaag aaattgtagt tgcacacgtt gacaaagttg tggttgattg tcttggcttt
    22981 tttacagtta tctataaata gttgaggaag agacttgaat cctatcaagt ctctttctcg
    23041 ataggttgct ttgtgatata attagtgtga aatctagtaa ataaatagtg tcagtagctt
    23101 gacacaagag ggacatattg aagaaggcga gaatttccat gattcggttg ttcgtgaggt
    23161 ctttgaggag actagcttga cgattggaaa tgcacgatta gtcggaataa agcattggcc
    23221 ggacaaggaa gggcatcgtt atattgtatt tctctataag gcaacagagt ttacaggaac
    23281 tatccgatca actgaagaag gtgaggtgcg ttgggtcgag aagtcggacc tgcctcagat
    23341 ggatttggcc tatgatttgc tagaaatact gaaagtcatg gatgagccag atttgtccga
    23401 gttcttttat actagaaaaa atgaagatgg agagtgggat aagaatttta ggtagaagct
    23461 agaaatagct tcttttttac gttatttgaa taaaaataca ataaataagt tgacgaatgt
    23521 ataaaaatga cataaaatgt ttttatcttt taaaaaagga gaaaaaatat gcattttact
    23581 acaatgaaag tccgatgttt tatataaaaa acggtataag tatgcacagg attattttaa
    23641 aggagaatat gatgatgaaa aaatatatta tgacaggctt ggttttactg gcaacgatga
    23701 ccctaagcgc ttgtagtgga aatgctactc aagaagatac ttctttgaag gatgttcagg
    23761 aaaagggaaa actaattgtt gcattgaatc cagaatttcc accatttgag tttagaacac
    23821 tggttgatgg caaagataca atcgttggag ctgacattga gcttgcaaaa gccattgggc
    23881 aagaattggg tgtagaagtc gaattttcag cgatgagttt tgataatgtt ttgaacaatg
    23941 tccagtcagg gcaatcggat attgccattt caggaatttc agccactgaa gagcgtgcaa
    24001 aagtgtatga tttttccatt ccttactaca cctcaaccaa taaagttatt ataaataaag
    24061 aggattttgc acaatataca tcgcttgatt ctctagctga ggcaaatata ggagcacaaa
    24121 aaggttctat tcaagaacaa atcgttaaag aacagcttcc gtcttccacg gttattgctc
    24181 tggcttcgaa cggagagctg attaatcaat taaaatcaca gaaggtagaa gcagttattt
    24241 ttgaagagcc gattgcgaaa gcctatgttg ctaaaaatga tgatttggtt attttagata
    24301 ctgagataaa aagtagctat tcagatgcct atgctattgc cttgccaaaa ggaagtacag
    24361 ctttaaagga aaaagttgac tctgtcatta caaaactagt agaatctgga cagatggatc
    24421 aatttgttca agaagcctat gaattatcca ttgctaacaa ttaaatttta tacaattaaa
    24481 ttgaataaaa ataatatttt cttgacaaat gtataaaaat gaattaaaat gagaatacat
    24541 tttgaaaaac tgcaagaaaa tacaatgaaa atcaaaaagc ttgtgttttt tagaataggt
    24601 attttattaa aataaagaga aggtagttag gaaatatgaa aaaaatcttg gcattagcag
    24661 caacagtttt agcaggactg acattggcag cttgttcttc gacgtcatca caatccgcat
    24721 tagataaaat taaagaaaaa ggaacattgg tagtggcaac tagtccagac tatgctccat
    24781 tcgagtttca ggcactagtt gatggaaaga atgaagttgt tggtgcagat attatgttgg
    24841 ctcaaaaaat agccgacgaa cttggggtca agcttgaagt ttcagcaatg agttttgaca
    24901 atgtattgtc tagcgttcaa aatggcaaag ctgatattgc aattgctggt ctatcgtatt
    24961 cggaagagcg tgcaaaagtt tttgatttct ctgaaagtta ctatcaaatt tctgatgtct
    25021 tacttatcaa aaaagatagc gccaattcac tcacttcaat tgatgctatg agtgggaaga
    25081 ctcttgcggt acaaaagggg tcaacacagg aagcctacgc acaggaaaat attagtcaag
    25141 ctaacctaat ttctttaacc ttgatgggtg aagctgtaaa tgagctcaaa tcaggaaaag
    25201 ttgatgctat tttaatggat tctccagttg ctgctggtta tgtttcacag aattcagatt
    25261 tagccgttgc atccgttgaa tttccaacga ttgatgagaa ttcgaaagtc attgctttgc
    25321 caaaaggtag tacagaacta aaaactgcga tagacaaggt tatcgcagaa gtaaaagcaa
    25381 gtggtgagtt tgatactttc cttgagaaag ctgcaacata tacaagtgtt gaataagaga
    25441 aaggaacaat catcggaaac ggtggttgtt tttgcatgca aaaagaatgg aataagtgag
    25501 ccacacccca aaagttagac agaaaattgg ggtcggttca atactccatt ctttatagat
    25561 aattatttca cacgctctag ataaaaactg gtcaaacgtg gtacagtaat tctagctcca
    25621 ttttcatcgg gatagaggct aaatgtgttc attggaatag cattagatga gaagacaagt
    25681 ttatattcgc tgtcagctgg caaatccaag tgtacatcaa atagttcttg atcattaaag
    25741 ttatgaatag ttaagatttc ttgctcatca ctagtgcgag aaaaagcata caggcttgct
    25801 tcttcatcta tttttaccca attaaatcct ttttcatagg cttggtagtc atatttccag
    25861 aaagcatcat gttctttata gaaagtagat aatgttttca tcatttgata gaaagaatgg
    25921 tggattggaa attgtagcag tccccagtcc atttctgtat attcgtgcca ttcacggata
    25981 tgaccccatt catttcccat gaagagtaat tt
//
