LOCUS       NZ_CP049945            20975 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces koyangensis strain SCSIO 5802 chromosome, complete
            genome.
ACCESSION   NZ_CP049945
VERSION     NZ_CP049945.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces koyangensis
  ORGANISM  Streptomyces koyangensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces
            aurantiacus group.
REFERENCE   1  (bases 1 to 6861301)
  AUTHORS   Ding,W.
  TITLE     Genome mining and metabolic profiling illuminate the polycyclic
            tetramate macrolactams from Streptomyces koyangensis SCSIO 5802
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861301)
  AUTHORS   Ding,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2020) Chinese Academy of Sciences, Key Laboratory
            of Tropical Marine Bio-resources and Ecology, No.164 Xingang west
            Road, Guangzhou, Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016803985.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 03:33:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,078
            CDSs (total)                      :: 5,988
            Genes (coding)                    :: 5,861
            CDSs (with protein)               :: 5,861
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 60 of 127
            Pseudo Genes (incomplete)         :: 90 of 127
            Pseudo Genes (internal stop)      :: 7 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:34:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4794911
            Orig. end                         :: 4815886
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP049945.1.
            Bacteria and source DNA available from Deep sea sediment.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10975
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(566..889)
                     /locus_tag="G9U55_RS21405"
                     /old_locus_tag="G9U55_21565"
     CDS             complement(566..889)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950752.1"
                     /locus_tag="G9U55_RS21405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21565"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_203215589.1"
                     /transl_table=11
                     /translation="MAWLLVVVAGLLETGFAVCLKLSHGFTRLWPTVAFAAFALGSFGL
                     LTLALKRLDVGPAYAVWTGIGAAGTATYGMIFLGDVVSVLKIVSITLVICGVIGLQLSG
                     STQ"
     gene            complement(1017..2033)
                     /gene="rsgA"
                     /locus_tag="G9U55_RS21410"
                     /old_locus_tag="G9U55_21570"
     CDS             complement(1017..2033)
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966421.1"
                     /locus_tag="G9U55_RS21410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21570"
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="WP_003950753.1"
                     /transl_table=11
                     /translation="MRRYGKNPDEDDIRVRPSRRGSRPRTHTRPKHEDAAEGMVLTVDR
                     GRITCLVEGRTVTAMKARELGRKAAVVGDRVALVGDLSGQKDTLARIVRIEERASVLRR
                     TADDDDPYERVVVANADRLAIVTALADPEPRPRMIDRCLVAAYDGGLEPVLVLTKSDLA
                     SPDSLLDTYRALGVPYVVTSREELEDGSAVERVRELLDGHVTAFVGHSGVGKTTLVNAL
                     VPEEQRRVTGHVNAVTGRGRHTTVSALALPLADAAPGSWVIDTPGVRSFGLHHVDPSRV
                     IHAFPDLEPGTEECPRGCSHDEPECALDQWVADGHADPARLNSLRRLLATRERREGD"
     misc_feature    2050..2065
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(2051..3403)
                     /gene="aroA"
                     /locus_tag="G9U55_RS21415"
                     /old_locus_tag="G9U55_21575"
     CDS             complement(2051..3403)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642411.1"
                     /locus_tag="G9U55_RS21415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21575"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_129848096.1"
                     /transl_table=11
                     /translation="MTLNPVSTPLWPAPYATGAVEATVQVPGSKSVTNRALVLAALAAE
                     PGWLRRPLRSRDTVLMAEALRTLGVGIEETVSSDSAAPGSALGAGGEAWRIIPSGLRGP
                     ATVDVGNAGTVMRFLPPLATLADGDIRFDGDPRSYERPLHGVIDALRALGARIDDDDRG
                     SLPLTVHGSGSLDGGTVEIDASSSSQFVSALLLSAPRFNQGVEVRHIGPRLPSMPHIRM
                     TVDMLRRVGAQVDEPESGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGGRV
                     VIPDWPAHTTQPGDRLREIFTTMGGSCELTEAGLVFTGSGRVHGIDVDLGEVGELTPGI
                     AAVAALADGESVLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLRIRPRPLHGGV
                     FHTYDDHRMATAGAILGLVVKGVEIENVATTAKTLPDFPDLWTGMLDGTGQ"
     gene            complement(3446..4171)
                     /locus_tag="G9U55_RS21420"
                     /old_locus_tag="G9U55_21580"
     CDS             complement(3446..4171)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="G9U55_RS21420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21580"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_203215590.1"
                     /transl_table=11
                     /translation="MQSTTTAAPATDLWDRVTGTQTAPEFWLVVATGVAALAVVLWGPA
                     WRPARNAITIAHEGGHGLIALVTGRTLEGIRLHSDTSGLTVSRGRPTGPGMILTALAGY
                     TAPSLLGLGGAWLLASGHITLLLWVATALLLALLVMVRNAYGVLTVLITGGLFVAVSWL
                     ADSEVQALFAYAAVWFLLIGGVRPVFELQSKRRRGGAPDSDADQLARLTHAPAAIWLLL
                     FHAVALCSLIGGGGWLLGR"
     gene            4261..5133
                     /locus_tag="G9U55_RS21425"
                     /old_locus_tag="G9U55_21585"
     CDS             4261..5133
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="G9U55_RS21425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21585"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_129848094.1"
                     /transl_table=11
                     /translation="MCGRYAATRSPEDLSEIFGVEKTELSEAADGQEDGHEAGASPVPT
                     ETLVPDWNVAPTKQVPAILDRPVKGSEDPRPVRQLRMLTWGLVPSWATSPDGGARMINA
                     RAETVHEKPAYRRAFASRRCILPADGYYEWVTAPEERKLEEEGKRKRARKQPYFVTPAD
                     GSVFAMAGLYEFWRDPSLPGDHPRAWWVTCSVITTEAEAAPLGVGPEEGPRALADIHPR
                     MPLMLTPDKWDAWLDPSKTDVGEVRELLGAPPEGLMRAYPVATAVSNVRNNGPGLVSEL
                     DGPEVGTLF"
     misc_feature    4309..4323
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            5504..6190
                     /locus_tag="G9U55_RS21430"
                     /old_locus_tag="G9U55_21590"
     CDS             5504..6190
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415707.1"
                     /locus_tag="G9U55_RS21430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21590"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_404830029.1"
                     /transl_table=11
                     /translation="MNVSRSEGVAVSAVLEAGERVTVATDVGEARVTWVRAEVPRLVLA
                     LGHGAGGGVEARDLVALAGVLPGAGVSVALVEQPWRVAGKKVAPAPKTLDKGWEAVWGE
                     VAGEGVPVVAGGRSAGARVACRTGAGLGAAGVLALSFPLHPPGKPERSRAEELLGTGVP
                     TMVVQGGRDPFGRPEEFPAGSYELAEVAYGDHGFAVPKKAPVGQEEALGVITDAVGAWL
                     ERLPVG"
     misc_feature    5687..5689
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6450..6464)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            6656..7330
                     /locus_tag="G9U55_RS21435"
                     /old_locus_tag="G9U55_21595"
     CDS             6656..7330
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="G9U55_RS21435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21595"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_026048295.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGSQDVPEKPEETSAERTARFERDALAFLDQMYSAAL
                     RMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKKQREPQRS
                     AAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKSALQAIPEEFRIAVYLADVEG
                     FAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGSGASAAEPNERKGA
                     GS"
     gene            7327..7635
                     /gene="rsrA"
                     /locus_tag="G9U55_RS21440"
                     /old_locus_tag="G9U55_21600"
     CDS             7327..7635
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642406.1"
                     /locus_tag="G9U55_RS21440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21600"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_101278340.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDHEMPDSDSNKIRTHFDECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPADLRDKVISRLDMIRAGQAVPQHDIVATEAADTP"
     gene            7870..8862
                     /locus_tag="G9U55_RS21445"
                     /old_locus_tag="G9U55_21605"
     CDS             7870..8862
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415712.1"
                     /locus_tag="G9U55_RS21445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21605"
                     /product="hypothetical protein"
                     /protein_id="WP_101278341.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARTAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKIPGDAAASGEPSGMGLGSAAVRISPEGEAEVVWGRRLDPARIEVQSIPL
                     PSSGRRWGEVILHDGVPHGERTTASGDTYPVFDEIELWAPSPVPTWVVLLEAQAPADRD
                     ALELLAADAGFAAEDWSSSVRLLCRTCSESRMPSDEGGGERHVDPHDHSEPGQPGPLGH
                     RTTGGEGDLWVPERECGIAAPPALVRGLLDGWVADSPDTRAWRDLEEVC"
     gene            8955..9611
                     /gene="def"
                     /locus_tag="G9U55_RS21450"
                     /old_locus_tag="G9U55_21610"
     CDS             8955..9611
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="G9U55_RS21450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21610"
                     /product="peptide deformylase"
                     /protein_id="WP_101278342.1"
                     /transl_table=11
                     /translation="MAQQDTEQQAVAGGVLPVDDEGFVIDTEDTEEREAAYRARGTARP
                     ITVVGNPVLHRETKDVTAFDAELAQLVDDMFASQRAAEGVGLAANQIGVDKKVFVYDCP
                     DDEGVRHVGVVCNPVLDELPSERRVLDDSNEGCLSVPTAYAELARPDYAVVRGQDEKGN
                     PIVVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAEGTPRYETVPND"
     misc_feature    9703..9717
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.68"
                     /tool="antismash"
     misc_feature    9952..9965
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.14"
                     /tool="antismash"
     misc_feature    complement(9952..9965)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.17"
                     /tool="antismash"
     gene            10001..10975
                     /locus_tag="G9U55_RS21455"
                     /old_locus_tag="G9U55_21615"
     CDS             10001..10975
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470738.1"
                     /locus_tag="G9U55_RS21455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21615"
                     /product="terpene synthase family protein"
                     /protein_id="WP_203215591.1"
                     /sec_met_domain="T1TS (E-value: 7.4e-51, bitscore: 172.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESRAWLLEKRLMPADKVTRYADELRYTDLIAGYYVGAPREVISA
                     ISDFSTWFFVWDDQHDRDAVHGRRTAWYRLSAELHTALDAPGDHLAHPEPLVAAFAETV
                     HRLNGFLSPAWNHRFARHFHAIVGAYDQEFENRVTKVTPKVAEYIELRRHTFGHSVWID
                     LLEPTAGREIPAALRASGPFLSAARHCQDFSAWYNDLCSLPKELAGDDQHNLGISLIRH
                     EGLSLEEAVVEVRRRVENCVTEFEVAEKELRELLAGHLAALPGGAGSAEARSVAEAVES
                     AVFNMRNWFSSVYWFHHESGRYRVDSWDDRSTPPYVSDLAGDA"
     gene            10972..12339
                     /locus_tag="G9U55_RS21460"
                     /old_locus_tag="G9U55_21620"
     CDS             10972..12339
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950763.1"
                     /locus_tag="G9U55_RS21460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21620"
                     /product="cytochrome P450"
                     /protein_id="WP_203215592.1"
                     /sec_met_domain="p450 (E-value: 3.7e-78, bitscore: 261.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAESTTERPAAPGPRTAPLVAGSVPVLGHAPSLVRDPLAFLTGL
                     RDHGDLVRVKLGPKTAYAVCAPELVGALLRNSQEFQVGGPLWENLEVLLGKGVATSNGA
                     DHRRQRRMMQPAFRPERIASYATVMEEEARAMADRWRDGQVVDIGAETFSCAVRVVARS
                     LLEVDSIGAKADRISASLHTVFSGLYRRMILSFGPLHRLPTPANRRFERALADLHHLVD
                     EVIAERHAQGKGADDLLDILLTSEDGEGRPLSDQEIHDHLVSLIVAGAENVASTLAWCF
                     QLLTEHPAEEQRVAEEALSVAPDRPVNFGDLGSLDHTRNVIVESMRIRPAAWIFTRRAV
                     ADTELGGYRIPAGADIIYSAYAMQHDPRSFDRPDVFDPDRWIPARAEKVPQYAMMPFST
                     GNRKCPGDHFSMVEATLMLATVLPRWRLVPVPETDPAPRIGITLQPKRAVFRVESR"
     gene            complement(12427..13479)
                     /locus_tag="G9U55_RS21465"
                     /old_locus_tag="G9U55_21625"
     CDS             complement(12427..13479)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346718.1"
                     /locus_tag="G9U55_RS21465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21625"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_003950764.1"
                     /transl_table=11
                     /translation="MTTPDTTPAANAHTVGAAKNLLDPGFELTLRPMRYPDFYERYRDA
                     IKNTWTVEEVDLHSDVADLAKLSPGEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSP
                     EARLYLSRQLFEEAVHVQFYLTLLDTYLPDPADRADAFAAVENIPSIREKAEFCFRWMD
                     SVDKLDQLESQADRRKFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWV
                     FRDETMHMSFAFDVVDTVRKEEPELFDDKLQEQVVAMLKEAVEAELQFARDLCGDGLPG
                     MNTESMREYLECVADQRLTRLGFAPVYGSQNPFSFMELQGVQELTNFFERRVSAYQVAV
                     EGTVSFDDDF"
     gene            complement(13479..15854)
                     /locus_tag="G9U55_RS21470"
                     /old_locus_tag="G9U55_21630"
     CDS             complement(13479..15854)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966408.1"
                     /locus_tag="G9U55_RS21470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21630"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_203215593.1"
                     /transl_table=11
                     /translation="MTIAPADPSTAEVRAEEIQGPGGALLRTLTDLTADLPDTDPGRVA
                     AAALRGRNAASDEAELRSLATEAAAGLISEDPAYSKLAARLLTRTIAEEAAGQGVTTFT
                     ESVATGHREGLIADRTAAFVTAHAERLDALIDRAADDRFGYFGLRTVHSRYLLRHPHTR
                     QVIETPQHFMLRVACGLAEDDSVRALDEVASLYRLMSALSYLPSSPTLFNSGTRHPQMS
                     SCYLLDSPKDELESIYDRYHQVARLSKHAGGIGLAYSRIRARGSLIRGTNGHSNGIVPF
                     LNTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEEARRTHNLNLAHWIP
                     DEFMRRVDADADWSLFSPSDVPELTDLWGDAFDAAYRAAEARGLARRTIPARELYGRMM
                     RTLAQTGNGWMTFKDASNRTANQTALPGHTVHSSNLCTEILEVTDDGETAVCNLGSVNL
                     GAFVDGGAIDWERLDEAVRTAVVFLDRVVDINFYPTEQAERSNSRWRPVGLGAMGLQDV
                     FFQLRLPFDSPEAQRLSTRIAERIMLTAYETSCDLAEKSGPLPNWDRTRTARGVLHPDH
                     YDTDLAWPERWEALRARVAESGMRNALLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVQDLKRLGVWDARTREALREASGSVQGFAWIPEELRALYRTAWELPQ
                     RGLIDMAAARTPFLDQSQSLNLFMETPTIGKLSSMYAYAWKKGLKTTYYLRSRPATRIA
                     RAAGGSAPATATVPAQAAPDAEAIACSLENPESCEACQ"
     regulatory      complement(16017..16093)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(16108..16121)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(16115..16129)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(16146..16160)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.01"
                     /tool="antismash"
     gene            complement(16471..16713)
                     /locus_tag="G9U55_RS21475"
                     /old_locus_tag="G9U55_21635"
     CDS             complement(16471..16713)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642403.1"
                     /locus_tag="G9U55_RS21475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21635"
                     /product="YbdD/YjiX family protein"
                     /protein_id="WP_003950767.1"
                     /transl_table=11
                     /translation="MSGEAAHHPGRLGVLAHRVRAGVRWIGWYVREVSGETAYEKYAAH
                     VRRHDPDAEVMTRRQFERSRMDAREADPRDGFRCC"
     gene            complement(16710..18932)
                     /locus_tag="G9U55_RS21480"
                     /old_locus_tag="G9U55_21640"
     CDS             complement(16710..18932)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1185: carbon
                     starvation protein A"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642402.1"
                     /locus_tag="G9U55_RS21480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21640"
                     /product="carbon starvation CstA family protein"
                     /protein_id="WP_129848089.1"
                     /transl_table=11
                     /translation="MAEPAPPASGNRKLSAKSIAVWSLVAVVGAIAWSVLALSRGEEIS
                     AIWMLAAALGSYAIAYRFYSRFIANKVLKVDKNRATPAERLDNGVDFQPTDRRVLFGHH
                     FAAIAGAGPLVGPILAAQMGYLPGTIWIVAGVIFAGAVQDMVTLFFSTRRNGRSLGQMA
                     RDEIGPVGGVAALIAVFMIMIILLAVLALVIVNALAGSPWGVFSIGMTIPIALFMGIYL
                     RTLRPGKVTEVSVLGVALLLLAIVGGGWVAESSMADFFTLEPGTLVIWMVVYGFFASVL
                     PVWMLLAPRDYLSTFMKVGTIVLMAVCVIVAMPTLKMDGVTSFATSGAGPVFSGSLFPF
                     VFITIACGALSGFHSLVSSGTTPKMVQKETQIRMIGYGAMLTESFVAIMAMIAACIIDP
                     GLYFAINAPVGVIGDTVQSASEAVANLGFTITPDQLAQAAKDVEENSLLSRTGGAPTFA
                     LGMAEIFAAALGGAGMKAFWYHFAIMFEALFILTTVDAGTRVGRFMLQDTLGNVWKPMR
                     RVSWWPGVWITSAIVVGCWGYFLWVGVHDPLGGINQLFPLFGIANQLLAAVALAVCTTL
                     LIKSGRLKWAWVTGIPLAWDVAVTLTASWQKIFSDNPAIGFFAQRAKYQDGIDAGEVLA
                     PAKSMGDMHTVVTNSTVDGVLSIVFAVLIIIVLVDAGRVSYNAIRKPESVKLAEAPFEQ
                     SKIVAPAGMFATAEEKAELALVGAGAPASAGDGDGDAPAKQGGDKA"
     gene            complement(19435..20223)
                     /locus_tag="G9U55_RS21485"
                     /old_locus_tag="G9U55_21645"
     CDS             complement(19435..20223)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950769.1"
                     /locus_tag="G9U55_RS21485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9U55_21645"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_179230504.1"
                     /transl_table=11
                     /translation="MTTDAGGTRTRTAGEPATEPTSPVRATRVPKYYRLKRHLLDMTRT
                     LPPGTSVPPERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLT
                     SYTEDMRAQGLEPTSQLLEVGYITADDSLASLLDITAGGRVLRIERLRLASGEPMAIET
                     THLSAKRFPALRRSLVKYTSLYTALYEVYGVRPAEAEETIETSLATPREAALLATDVGL
                     PMLMLSRHSRDESGAPVEWVRSVYRGDRYKFLARLKRPVE"
     misc_feature    complement(20381..20396)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.28"
                     /tool="antismash"
     misc_feature    complement(20406..20421)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
     misc_feature    20867..20880
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.42"
                     /tool="antismash"
ORIGIN
        1 ctgctgatcg ccgccgaggc ccacctggcc cggcgcccct ggagcgcggt gcggatgggc
       61 gaggtcgcgg cctcggccgg ggtctcccgg cagacgctgt acaacgagtt cggcagcaag
      121 gaagggctcg tccgcgccct ggcccggcag gccgccgacg gctacctcgc cgggatcgaa
      181 cgggccctgg cccgtcccgc caccgacccc cgcgagcggc tgcgcgccgc cgccgactgg
      241 accgtggccg cagcccgccc cggcaccctg ctgcgctccc tgctgaccgg ctgctggggc
      301 gacccgctgc ccgctccgcg cccggcccgc accactgcca ccgcccccgc ccagcgccgc
      361 gccgaactcc cgctcccggg ccccggcgaa ctgctggccg ccgcccgcga ccgggccgtg
      421 gccaccctcg ccgagtccac gccgccccgc cccgacccac gcgaactggc ccgggagtgc
      481 gagtgcgccc tgcgcctggc gctgtccagg atcgtggcgc cgccggtggt gggaggcgcg
      541 ggggcggggc ggcggcgcgg gcgggtcact gggtcgagcc cgagagctgg aggccgatga
      601 cgccgcagat gacgagggtg atggagacga tcttcaggac cgagaccacg tcgccgagga
      661 agatcatgcc gtaggtggcg gtgccggccg cgccgatgcc ggtccacacc gcgtaggccg
      721 ggcccacgtc caggcgtttg agggccaggg tcagcaggcc gaagctgccc agggcgaacg
      781 cggcgaaggc gaccgtcggc cacagccggg tgaacccgtg cgacagcttg aggcagacgg
      841 cgaaacccgt ctccagcagc cccgcgacga cgaccagcag ccatgccatg aatgtgccct
      901 tccgcccgcc gaaacgatcc cgcgcgcacc ttgtacggct tcgggcgatt atgcccgtgt
      961 cgtccggtgc ggcaggcgac ccggcccggc tcgtcgcgcc gcaggtcgcg ccggggtcag
     1021 tcgccctcgc gccgctcccg ggtcgccagc agccgccgca gcgagttgag gcgggccgga
     1081 tcggcgtggc cgtcggccac ccactggtcg agggcgcact ccggctcgtc gtggctgcac
     1141 ccgcgcgggc actcctccgt ccccggctcc aggtcgggga aggcgtggat cacgcgggag
     1201 gggtcgacgt ggtgcagccc gaacgagcgc acacccggcg tgtcgatcac ccagctgccg
     1261 ggggcggcgt cggccagcgg cagcgccagc gccgagaccg tggtgtgccg gccgcggccg
     1321 gtcaccgcgt tgacgtggcc ggtgacccgc cgctgctcct cggggaccag cgcgttcacc
     1381 agcgtcgtct tgccgacacc cgagtggccc acgaaggcgg tgacatggcc gtccagcagc
     1441 tcccggaccc gctccacggc cgagccgtcc tccagctcct cccggctggt caccacgtac
     1501 ggcacgccca gcgcccggta ggtgtccagc agggagtcgg gggaggccag gtcggacttg
     1561 gtcagcacca ggaccggctc caggccgccg tcgtaggcgg cgaccaggca gcggtcgatc
     1621 atccggggcc ggggttccgg atcggccagc gccgtgacga tcgccagccg gtcggcgttg
     1681 gcgacgacca cccgctcgta cgggtcgtcg tcgtcggccg tgcggcgcag caccgaggcg
     1741 cgctcctcga tccgcacgat gcgcgccagg gtgtccttct gcccggagag atccccgacc
     1801 agcgccaccc ggtcgcccac caccgccgcc ttgcggccca gttcgcgggc cttcatcgcg
     1861 gtcaccgtgc ggccctcgac caggcaggtg atccggcctc ggtccacggt gagcaccatg
     1921 ccctcggcgg cgtcctcgtg cttggggcgg gtgtgggtac gggggcggct gccccggcgg
     1981 ctggggcgga cgcggatgtc gtcctcgtcg gggttctttc cgtaacggcg catcgttcag
     2041 ctcccggccg tcactgcccg gtcccgtcga gcatgccggt ccacaggtcg gggaagtcgg
     2101 gcagggtctt cgcggtggtg gcgacgttct cgatctcgac gcccttcacc accagtccca
     2161 ggatcgcacc ggcggtcgcc atccggtggt cgtcgtaggt gtggaagacg ccgccgtgca
     2221 gcgggcgggg gcggatgcgc aggccgtcgg cggtctccgt gacgtcgcca cccagctcgt
     2281 tgatctcctt ggtgagcgcc gcgagccggt ccgtctcgtg gagccggagg tgggcgacgc
     2341 cgcgcaggac ggactcgccg tcggccaggg ccgcgacggc cgcgatgccc ggggtcagct
     2401 cgccgacctc gccgaggtcc acgtcgatgc cgtggacgcg gcccgagccg gtgaagacca
     2461 ggcccgcctc ggtcagctcg caggaaccac ccatcgtggt gaagatctcc cgcagccggt
     2521 cacccggctg cgtggtgtgg gccggccagt cggggatgac cacgcggccg ccggtgacca
     2581 gggccgccgc caggaagggc tgggcgttcg agaggtccgg ctcgacggtg aggtcccggc
     2641 cgagcagggc gcccggggtg acccgccaga cgttgggctc gccacccgac tcgggctcgt
     2701 ccacctgggc gccgacccgg cgcagcatgt cgacggtcat ccggatgtgc ggcatcgagg
     2761 gcagccgggg gccgatgtga cggacctcga cgccctggtt gaagcggggc gccgacagca
     2821 gcagggcgct cacgaactgc gaggacgagg aagcgtcgat ctccaccgtg ccgccgtcca
     2881 gcgagcccga gccgtgcacc gtcagcggca ggctgccccg gtcgtcgtcg tcgatccggg
     2941 caccgagggc gcgcagcgcg tcgatcacgc cgtgcagcgg acgctcgtag gagcgcgggt
     3001 cgccgtcgaa gcggatgtcg ccgtcggcga gggtggcgag cggcggcagg aagcgcatca
     3061 cggtgcccgc gttgccgacg tcgacggtgg ccgggccgcg caggcccgac gggatgatcc
     3121 gccacgcctc accgcccgcg cccagggcgc tgcccggcgc cgccgagtcg gacgagacgg
     3181 tctcctcgat gcccacgccg agggtccgca gcgcctccgc catcagcacg gtgtcgcgcg
     3241 agcggagcgg ccggcgcagc cagcccggct cggcggcgag cgccgccagc accagcgcgc
     3301 ggttggtgac cgacttggac cccggtacct ggaccgtcgc ctcgacggct ccggtcgcgt
     3361 acggggcagg ccagaggggg gtggatacgg ggttcagggt catgccgtca ctttagtgcg
     3421 cccagcccct cccacccgtg cacggtcacc ggccgagcag ccagccgccc ccgccgatca
     3481 gggagcagag cgccaccgcg tggaagagga ggagccagat ggccgccggg gcgtgggtca
     3541 gccgggcgag ctggtcggcg tcggagtccg gggcgccgcc gcgccgccgc ttcgactgga
     3601 gctcgaagac cgggcgtacc ccgccgatca gcaggaacca gaccgccgcg taggcgaaga
     3661 gggcctgcac ctcggagtcg gccagccagg agaccgccac gaagaggccg ccggtgatca
     3721 gcaccgtcag caccccgtag gcgttgcgga ccatcacgag gagggcgagc agcagggccg
     3781 tcgccaccca gagcagcagc gtgatgtggc ctgacgccag cagccaggcg ccgccgaggc
     3841 cgaggaggga gggggcggtg tagccggcga gggcggtgag gatcatgccc ggcccggtcg
     3901 gcctgccccg gctcacggtc agtcccgagg tgtccgagtg gaggcgtatt ccctccaggg
     3961 tgcggccggt gaccagggcg atcaggccgt ggccgccctc gtgggcgatg gtgatcgcgt
     4021 tccgtgcggg gcgccaggcc gggccccaca ggaccacggc gagcgccgcc acgccggtcg
     4081 ccacgaccag ccagaactcg ggggcggtct gcgtcccggt gacgcggtcc cacaggtcgg
     4141 tggccggggc ggcggtggtg gtgctctgca tactcgggcg gctcctcgcg agggtgggac
     4201 gcgcggcccc ggggcccaac tggtggcggt ccggtggcac ggcctggcag tctggcacgt
     4261 atgtgcggac ggtacgcggc cacccggagc cccgaggacc tcagcgagat cttcggtgtc
     4321 gagaagaccg agctgagcga ggcggcggac ggccaggagg acggccacga ggcgggggcg
     4381 agccccgtgc ccaccgagac cctcgtcccc gactggaacg tggcgcccac caagcaggtt
     4441 cccgccatcc tcgaccggcc ggtcaagggg agcgaggacc cgcgccccgt acggcagttg
     4501 cggatgctga cctgggggct cgtcccctcc tgggccacct cgcccgacgg cggcgcccgg
     4561 atgatcaacg cccgcgccga gaccgtccac gagaagcccg cctaccgccg ggccttcgcc
     4621 tcgcggcgct gcatcctccc cgccgacggc tattacgagt gggtgaccgc tccggaggag
     4681 cggaagctgg aggaggaggg gaagcggaag cgggcccgta agcagcccta cttcgtgacg
     4741 cctgcggacg ggtcggtctt cgcgatggcc gggctgtacg agttctggcg tgatccctcg
     4801 ctgccggggg accatccgcg ggcctggtgg gtgacgtgtt ccgtcatcac gaccgaggcg
     4861 gaggcggcgc cgctcggggt ggggcccgag gaggggcctc gggcgctggc cgacattcat
     4921 cctcggatgc cgttgatgct gacgccggac aagtgggatg cgtggcttga tccgtcgaag
     4981 acggatgtgg gggaggtgcg ggagttgttg ggggcgccgc ctgaggggtt gatgcgggcc
     5041 tatcccgtgg ccacggcggt gagcaatgtg cggaacaacg ggcctgggct cgtgtccgag
     5101 ctggacgggc ctgaggtggg cacgctgttc tagcgggcgg gggcctcaag cgccggccgg
     5161 gctgatcagg ggtgtgctgt gcgtggcgac cgtgccggtc agggttggcc tcaagcgccg
     5221 gccgggctgt cattgggtgt gctcgccgtg gtaaccgtgc cggtcagaga tggcctcaaa
     5281 cgccggccgg gcttgaaagg tggcctcaaa cgccggccgg gctggatttt gccggccggg
     5341 cttggaggtg tgctggccgg gcttggaggt gtgctggctg gggcgccgtc ggtggtgccg
     5401 gaggggcgga gtggtgcggg gcgggtggtg ccggaggggc ggagtggtgc ggggcgggtg
     5461 gtgccggagg ggcggggtgt ggtcggcggg gcaggatggc gggatgaacg tatcgaggtc
     5521 tgagggtgtg gctgtttccg ctgtgctgga ggcgggggag cgggtgacgg ttgccacgga
     5581 cgtgggggag gcgcgggtca cctgggtgcg ggcggaggtg cctcggcttg tgctggcgct
     5641 cgggcatggg gccgggggtg gggtggaggc tcgggatctg gtggcgttag cgggggtgtt
     5701 gccgggggcc ggggtgagtg tggcgttggt ggagcagccc tggcgggtgg cggggaagaa
     5761 ggtggcgccg gcgccgaaga cgctggacaa ggggtgggag gcggtctggg gcgaggtggc
     5821 cggggagggg gtgccggtgg tggcgggcgg gcgcagcgcg ggggcacggg tcgcctgccg
     5881 gaccggggcc gggctggggg cggccggggt gctcgcgctg agctttccgc tgcatccgcc
     5941 ggggaagccg gagcggagcc gggccgagga gctgctcggg acgggggtgc cgacgatggt
     6001 ggtgcagggc gggcgggacc cgttcgggcg gccggaggag tttcccgcgg ggagctacga
     6061 gctggccgag gtggcgtacg gcgatcacgg gttcgccgtg ccgaagaagg cgcccgtcgg
     6121 ccaggaggag gcgctcgggg tgatcacgga cgcggtgggg gcgtggctgg agcggctgcc
     6181 ggtgggctga ggcggtcacg gggccggccg aggcgggtca caccctcggc tgaggggggg
     6241 gcgtcgcgtc ggccggggcg ggcgtcgcgt cgggctgcgg tgggtcacgg ggtgggctga
     6301 ggtgggcgtc gcgtcgggcg gggtggggta cggggtgggc tgaggtggtc acggcgtggg
     6361 ctggggcggg cgtcgcggtg gacggcggcg ggccttgtgg gggacgggaa tgccgagcgg
     6421 gtggcggctg ttgtgtgggg cgaaggtgct tcgacagcgt tgatcacgag aggaagtccg
     6481 ccgcatgggt tcgaccatct gcccgagccg cgagcgcgcc accgacctgg agtggtcggt
     6541 gctgcacgcg cccgtgcgca ctggctccgg ccgggatcgc cgggaagtcc aggagcgtgg
     6601 tctatcctcc gattcgggcg gtccggccgg cgggcccgcc acagcgctga aggaggtggg
     6661 tccggtcacg gggaccgacg cgggaagcca ggacgtaccc gagaagcccg aggagacctc
     6721 ggcggagcgg accgcgcggt tcgagcggga cgcgctcgcc ttcctcgacc agatgtactc
     6781 ggcggccctg cggatgaccc gcaacccggc cgacgccgag gacctggtcc aggagaccta
     6841 cgccaaggcg tacgcgtcgt tccaccagtt ccgtgagggc accaacctca aggcgtggct
     6901 gtaccggatt ctcaccaaca ccttcatcaa ctcgtaccgc aagaagcagc gtgagcccca
     6961 gcgcagcgcc gccgaggaga tcgaggactg gcagctggcg cgtgccgagt cgcacatgtc
     7021 gaccggtctg cgctccgccg agtcccaggc gctggaccac cttcccgact ccgacgtgaa
     7081 gtccgccctc caggcgatcc ccgaggagtt ccgcatcgcc gtctatctgg ccgatgtcga
     7141 ggggtttgcg tacaaggaga tcgcggacat catgggtaca cccatcggga cggtgatgtc
     7201 ccgcctgcac cgcggccgcc gccagctgcg cggcatgctg gaggactacg cccgcgagcg
     7261 cgggctggtc cccgccggtt ccggggcgag cgcggcggaa ccgaacgagc ggaaaggcgc
     7321 gggctcatga gctgcggaga gccgcacgag acggattgca gtgaagtcct ggaccatctc
     7381 tacgagttcc tcgaccacga gatgcccgac agtgactcca acaagatccg cacgcacttc
     7441 gacgagtgct ccccctgcct ggagaagtac ggtctggagc aggccgtcaa gaagctggtc
     7501 aagcggtgct gcggtcagga cgacgtcccc gcggacctgc gggacaaggt gatcagccgc
     7561 ctggacatga tccgggcggg ccaggcggtc ccgcagcacg acatcgtcgc gacggaggcg
     7621 gcggacacgc cctgacgtcc ggggcggccg gggagcgggc ggatacaggc cggacgctcc
     7681 ccgggcaagt cactcgatag ggcgacccgg tccgggaagg tctgcacctc acgccagtgg
     7741 gtaacccatg ggtaatgagc gacgccccaa ccgtccgtgg ttggatgcga agaggtaccc
     7801 cgtccccagg ctcagcaccg gcgcacgggc gggggacccg aagggaccgg acaccggcag
     7861 gcgggaatcg tgaggatctt cggcaaggga cggcaccgcc cctccgcctc ctggcggcag
     7921 gcgaccgacc gagcgttcac cttgatcggc gacggccgtt acgaggacgc gggcgccctg
     7981 ctcacgcgcg ccgccgacct ggagccgtgg ctctccgagt cctggttcaa cctcgccctg
     8041 ctccacaagt tccgccacga ctgggaacag gcccgtaccg cgggcctgcg cgccgtcgcg
     8101 ctgctggacc gggacacggg cgcccccgac tggtggaacg tcggcatcgc cgccaccgcc
     8161 ctccaggact ggccgctggc ccgccgcgcc tggcaggcgt acggcctgaa gatccccggg
     8221 gacgcggcgg cctccggcga gccgtccggg atggggctgg gcagcgccgc cgtgcggatc
     8281 tcccccgagg gggaggcaga ggtggtctgg ggccggcggc tggacccggc ccgcatcgag
     8341 gtccagtcga tcccgctgcc ctcctccggc cgccgctggg gcgaggtgat cctgcacgac
     8401 ggggtcccgc acggtgagcg gaccaccgct tcgggtgaca cctatccggt cttcgacgag
     8461 atcgagctgt gggcgccctc cccggtgccg acctgggtgg tgctgctgga ggcgcaggcc
     8521 ccggccgacc gggacgcgct ggagctgctg gccgccgacg ccgggttcgc cgccgaggac
     8581 tggtcctcgt cggtgcggct gctctgccgg acctgctcgg agagccggat gcccagcgac
     8641 gagggcggag gcgagcgcca cgtcgatccg cacgaccaca gcgaaccggg gcagcccggc
     8701 ccgctgggcc accggaccac cggcggcgag ggcgacctgt gggtccccga gcgcgagtgc
     8761 ggcatcgccg ccccgcccgc cctggtgcgc ggcctgctcg acggctgggt cgccgacagc
     8821 ccggacaccc gcgcctggcg cgacctcgaa gaggtgtgct gagccgctcc gtcctcgcgg
     8881 ccacccgcgc cccggccccc gcgtaggctg tacgggcacg gacaacgggt tcccaggaag
     8941 gcgcggaagc ggacatggcg cagcaggaca cggagcagca ggcggtggcg ggcggtgtgc
     9001 tgccggtcga cgacgaggga ttcgtcatcg acaccgagga caccgaggag cgtgaggcgg
     9061 cctaccgcgc ccggggcacc gcgcgtccga tcaccgtggt gggcaacccg gtgctgcacc
     9121 gcgagacgaa ggacgtgacg gccttcgacg cggagctggc ccagctggtg gacgacatgt
     9181 tcgccagcca gcgggcggcg gagggcgtgg gcctggccgc caaccagatc ggcgtggaca
     9241 agaaggtctt cgtctacgac tgcccggacg acgagggcgt gcgccacgtc ggcgtggtct
     9301 gcaacccggt cctggacgag ctgccctccg agcgccgcgt cctcgacgac tccaacgagg
     9361 ggtgcctctc ggtccccacc gcctacgcgg agctggcccg ccccgactac gcggtggtcc
     9421 gcggccagga cgagaagggc aacccgatcg tggtgcgcgg caccggctac ttcgcccgct
     9481 gcctccagca cgagacggac cacctgtacg gctacctcta catcgaccgg ctctccaagc
     9541 gcgagcgcaa ggacgccctg cggcagatgg ccgagggcac cccgcgctac gagacggtcc
     9601 ccaacgactg aggcgcgccc ccgccggccc gccgccgcgc acccgcaccg ccccgctctc
     9661 cccgtacggg aggcggggcg gtggtgtgtc gggggcatga tcaattttca gacaggtatg
     9721 gcggtcttcg ggtcggcgag gggtggcgaa tggagcaaat ctgttccctc attggtcagt
     9781 tgtggtgctc aatggaaagg gcggggggga tacaccaccg cgcggcgccc cgctcggcgc
     9841 ggggcaccgg cagaaagcgg atgaaagggg tttgttcgtg cctgctttcc cacacagcac
     9901 cgcacgggcg cagacgactt cggtgcccga ggcgctggcg ttgcccgtga tcgaacaagc
     9961 gtttccgcga catcgccatg agtattggcc aaagcttcag gtggagtccc gcgcctggct
    10021 gctcgaaaag cgcctgatgc ccgccgacaa ggtcacccgc tatgcggacg agctccgcta
    10081 caccgacctc atcgccggct actacgtggg agcgccgagg gaggtcatct cggcgatttc
    10141 cgacttcagc acctggttct tcgtctggga cgaccagcac gaccgggacg ccgtccacgg
    10201 gcggcgcacc gcctggtacc ggctcagcgc cgaactgcac accgcgctgg acgcccccgg
    10261 cgaccacctg gcacacccgg agccgctggt cgcggccttc gccgagaccg tccaccggct
    10321 gaacggcttc ctcagccccg cctggaacca ccgtttcgcc cgccatttcc acgccatcgt
    10381 cggcgcttac gaccaggaat tcgagaatcg cgtcaccaaa gtcaccccca aggtcgccga
    10441 atacatcgaa ctgcgccgcc acacgttcgg ccactccgtc tggatcgacc ttctcgaacc
    10501 caccgcggga cgagagatcc ccgcagccct gagggcgagc ggtccctttc tctcggcggc
    10561 ccgtcactgc caggatttct ccgcctggta caacgacctc tgctcactcc cgaaggaact
    10621 cgccggcgac gaccagcaca atctgggaat cagtctcata cgccatgagg gactgtcgct
    10681 cgaagaagcc gtggtggagg tgaggagacg cgtcgagaac tgcgtcaccg aattcgaggt
    10741 ggcggagaag gaattgcggg aactcctcgc cggacatctc gccgcactgc ctgggggagc
    10801 cggctccgcc gaggccaggt ccgtcgccga ggcggtcgag tcggccgtct tcaacatgcg
    10861 gaactggttc tcctccgtct actggttcca ccacgagtcc ggccgctacc gcgtcgacag
    10921 ctgggacgac cggagcaccc cgccctacgt cagcgacctg gcaggtgacg cgtgagcgcc
    10981 gaatcaacca ccgaacgccc agccgccccg ggcccgcgca ccgcgcccct ggtggccggc
    11041 agcgtgcccg tcctcggcca cgccccgagc ctggtccgcg acccactggc cttcctcacc
    11101 gggctgcgcg accacggcga cctggtccgc gtgaaactcg gcccgaagac ggcgtacgcg
    11161 gtctgcgccc ccgagctggt cggggcgctg ctgcgcaact ctcaggagtt ccaggtcggc
    11221 ggaccgctct gggagaacct cgaagtgctg ctcggcaagg gggtggccac cagcaacggg
    11281 gccgatcacc gccgccagcg ccgcatgatg cagcccgcct tccggcccga gcggatcgcc
    11341 tcgtacgcga ccgtgatgga ggaggaggcg cgggcgatgg ccgaccggtg gcgggacggg
    11401 caggtggtgg acatcggcgc cgagacgttc agctgcgcgg tgcgggtggt cgcccgctcg
    11461 ctgctggagg tcgactcgat cggcgccaag gcggaccgga tcagcgcctc gctgcacacc
    11521 gtcttcagcg gcctgtaccg gcggatgatc ctctccttcg gaccgctgca ccggctgccg
    11581 acccccgcca accggcgctt cgagcgggcg ctggccgacc tccaccacct cgtcgacgag
    11641 gtgatcgccg agcggcacgc gcagggcaag ggcgccgacg acctcctcga catcctgctc
    11701 acctccgagg acggcgaagg caggccgctc agcgatcagg agattcacga ccatctcgtc
    11761 tcgctgatcg tcgccggggc cgaaaatgtc gcctcgacac tcgcctggtg cttccagctc
    11821 ctcaccgaac atccggccga ggaacagcgg gtggccgagg aagcactatc cgtggcgccg
    11881 gaccgaccgg tcaatttcgg cgatctgggc tccctcgacc acacccgcaa tgtcatcgtc
    11941 gaatcgatgc ggatacggcc cgcggcgtgg atattcaccc gccgggccgt cgccgacacg
    12001 gaactcggtg gctatcgcat tccagccgga gcggacatca tctacagcgc gtatgcgatg
    12061 cagcacgatc cgcgctcatt cgaccggccg gacgtgttcg acccggaccg gtggattcct
    12121 gcacgggccg aaaaggtacc gcagtacgcg atgatgccgt tcagcacggg caaccggaaa
    12181 tgccccggcg accacttcag catggtcgag gccacgctga tgctcgccac cgtgctgccc
    12241 cgctggaggc tcgtccccgt ccccgagacc gacccggcac cccggatcgg gatcaccctc
    12301 cagcccaagc gtgccgtctt ccgggtcgag agccgctgac ccgcaccgcg cgcccagcac
    12361 cgacgcccgc cgcccggccc tcaggacgag gggccgggcg gcgggcgttc gcgggggcgg
    12421 ggccggtcag aagtcgtcgt cgaaggagac ggtgccctcg accgcgacct ggtaggccga
    12481 gacccggcgc tcgaagaagt tggtcagctc ctgcacaccc tggagctcca tgaaggagaa
    12541 ggggttctgc gagccgtaga ccggggcgaa gcccagccgg gtgagccgct ggtcggcgac
    12601 gcactccagg tactcgcgca tcgactcggt gttcatgccg ggcaggccgt ccccgcacag
    12661 gtcgcgggcg aactggagct cggcctcgac ggcctccttg agcatcgcga cgacctgctc
    12721 ctggagcttg tcgtcgaaga gctccggctc ctccttgcgg accgtgtcga ccacgtcgaa
    12781 ggcgaagctc atgtgcatcg tctcgtcgcg gaagacccag ttggtgccgg tcgccagccc
    12841 gtgcagcagc ccgcgcgagc ggaaccagta cacgtaggcg aacgccccgt agaagaagag
    12901 gccctcgatg caggcggcga agcagatcag gttgagcagg aacttgcggc ggtccgcctg
    12961 gctctccagc tggtccagct tgtccaccga gtccatccag cggaagcaga actccgcctt
    13021 ctcacggatc gaggggatgt tctccaccgc cgcgaaggcg tccgcgcggt ccgccgggtc
    13081 gggcaggtag gtgtcgagca gcgtcagata gaactggacg tgcacggcct cctcgaagag
    13141 ctgccggctc aggtagagcc gcgcctcggg ggagttgatg tgcttgtaca gggtcagcac
    13201 gaggttgttg gcgacgatcg agtcacctgt ggcgaagaag gcgaccagcc gcccgatcag
    13261 gtgctgctca cccggagaga gcttcgccag gtcggcgacg tcggagtgga ggtcgacctc
    13321 ctcgacggtc caggtgttct tgatcgcgtc ccggtagcgc tcgtagaagt ccgggtaccg
    13381 catcgggcgc agggtcagct cgaagccggg gtcgagcagg ttcttcgccg cgccgacggt
    13441 gtgcgcgttc gctgccgggg tggtgtcggg ggtggtcatt actggcatgc ctcgcaggac
    13501 tcggggttct ccagggagca ggcgatggcc tccgcgtcgg gggccgcctg cgcggggacg
    13561 gtggcggtgg cgggggcgga gccgccggcg gcacgggcga tccgcgtggc cgggcgggac
    13621 cgcaggtagt acgtggtctt cagccccttc ttccaggcgt acgcgtacat cgagctgagc
    13681 ttgccgatgg tgggcgtctc catgaacagg ttgagcgact ggctctggtc caggaacggg
    13741 gtccgggccg ccgccatgtc gatcaggccg cgctgcggca gctcccaggc ggtgcggtac
    13801 agcgcccgca gctcctcggg gatccaggcg aagccctgca ccgaaccgct cgcctcgcgc
    13861 agcgcctccc gggtccgcgc gtcccagacg ccgagccgct tcaggtcctg caccaggtag
    13921 gagttgacct ggaggaactc cccgctcagc gtctcgcgct tgaagaggtt ggagacctgc
    13981 ggctcgatgc actcgtagac accggcgatc gaggcgatgg tggccgtcgg ggcgatggcg
    14041 aggagcagcg cgttccgcat gccgctctcc gcgacccggg cgcgcagcgc ctcccaccgc
    14101 tccggccagg ccaggtcggt gtcgtagtgg tccgggtgga gcacgccccg cgcggtgcgg
    14161 gtgcggtccc agttcggcag cgggccgctc ttctcggcga ggtcgcagga ggtctcgtac
    14221 gcggtgagca tgatgcgctc ggcgatccgc gtggagagcc gctgggcctc gggggagtcg
    14281 aagggcagcc ggagctggaa gaagacgtcc tggagcccca tcgcgcccag gcccaccggc
    14341 cgccagcggg agttggagcg ctcggcctgc tcggtcgggt agaagttgat gtcgaccacg
    14401 cggtcgagga agaccacggc ggtgcgcacc gcctcgtcca gccgctccca gtcgatcgcg
    14461 ccgccgtcga cgaaggcgcc gaggttgacc gagccgaggt tgcagacggc cgtctcgccg
    14521 tcgtcggtga cctccaggat ctccgtgcac aggttcgagg agtgcacggt gtggcccggc
    14581 agcgccgtct ggttggcggt gcggttggag gcgtccttga aggtcatcca gccgttgccg
    14641 gtctgggcga gggtgcgcat catccggccg tacagctcgc gcgccgggat ggtccgcctg
    14701 gcgagacccc gcgcctcggc cgcgcggtac gccgcgtcga aggcgtcgcc ccacaggtcg
    14761 gtcagctcgg ggacgtccga gggggagaag agcgaccagt cggcgtcggc gtcgacccgg
    14821 cgcatgaact cgtccggaat ccagtgcgcg aggttgaggt tgtgggtgcg ccgggcctcc
    14881 tcgccggtgt tgtcccgcag ctccaggaac tcctcgacgt cggcgtgcca ggtctccagg
    14941 tagaccgcgg ccgcgccctt gcgccggccg ccctggttga ccgcggccac cgaggcgtcg
    15001 agcgtgttga ggaacggcac gatgccgttg gagtgcccgt tggtgccgcg gatcagcgaa
    15061 ccccgggcgc ggatacggga gtaggcgagg ccgatgccgc cggcgtgctt ggagagccgg
    15121 gcgacctggt ggtagcggtc gtagatcgac tccagctcgt ccttcgggga gtccagcagg
    15181 tagcaggagg acatctgcgg gtgccgggtg ccggagttga agagggtggg ggaggagggc
    15241 aggtaggaga gggcgctcat cagccggtag agcgaggcga cctcgtcgag agcccggacc
    15301 gagtcgtcct cggcgaggcc gcaggcgacg cggagcatga agtgctgggg cgtctcgatg
    15361 acctggcggg tgtgcgggtg gcgcagcagg tagcggctgt gcacggtgcg caggccgaag
    15421 tagccgaagc ggtcgtcggc cgcccggtcg atcagggcgt cgagccgctc ggcgtgggcg
    15481 gtgacgaagg cggcggtgcg gtcggcgatc aggccctcgc ggtggccggt ggcgaccgac
    15541 tcggtgaagg tggtgacgcc ctggcccgcg gcctcctcgg cgatggtgcg ggtcagcagg
    15601 cgggcggcga gcttggagta ggcggggtcc tcggagatca gaccggcggc ggcctccgtc
    15661 gcgagcgacc gcagctcggc ctcgtccgag gcggcgttgc ggccccggag agcggcggcg
    15721 gcgacccggc cggggtcggt gtcggggaga tccgcggtga ggtcggtgag ggtacgcagc
    15781 agcgcgcccc cggggccctg gatctcctcg gcccgcacct cggccgtcga cggatcggct
    15841 ggcgcgatgg tcatgaagct ctccctcgct cggctcggag cctcgcggag ggcagcgggt
    15901 gcgggcgggc ggccgggctt gatgggcaca cggctccgca cgcgtccgcg agcccattcc
    15961 acgaggcccg gacgacatcg gcacccggac cggacggccg ggtgcgctgt tcggcaggtc
    16021 ttcggactcg tgggtacgcg aaagcgcacc aacacaccgt tgcgggacag ttccggactt
    16081 ccaccggatt cccctgcggc gacagcgagc atgagcatac atcttgtgcc gcgctcgcga
    16141 agcggcccca tatcttgtgt cgggtgtgct gtgaggtggg tcattcgacc cacccgcacc
    16201 ggatgcccga acctcgcgga gacgccctcg gacggggtcc gggtacccgt cggacaggtc
    16261 gtgcgcgggc tcctgagggg ccgtcggcgc cccggagggg aacgccccgg ggacgggccc
    16321 ggcaagacct cacgggcggc gcgcggagcg gtacggcgac ctggagagcg tacgcgcccg
    16381 gaccggggtg gcggccgcca ggccccccgg cccgggaaac agcgaagccg ccggccccct
    16441 cgatcgggga ccggcggctt caaccggcgg tcagcagcag cggaatccgt cgcgcgggtc
    16501 cgcctcgcgg gcgtccatgc gactgcgttc gaactgcctg cgggtcatca cctcggcgtc
    16561 cgggtcgtgg cgcctcacgt gcgcggcgta cttctcgtac gccgtctcgc ccgacacctc
    16621 ccggacgtac cagccgatcc agcggacgcc ggcgcgcacg cggtgggcca ggacgccgag
    16681 gcgtccgggg tggtgggccg cctcgccgct catgccttgt cgccgccctg cttcgcgggg
    16741 gcgtcgccgt cgccgtcacc ggcggaggca ggggcaccgg cgccgacgag ggccagttcg
    16801 gccttctcct cggcggtggc gaacatcccg gccggggcga cgatcttcga ctgctcgaag
    16861 ggcgcctcgg ccagcttgac cgactcgggc ttgcggatcg cgttgtagct gacgcggccc
    16921 gcgtcgacca ggacgatgat gatcagcacc gcgaagacga tcgacaggac gccgtccacg
    16981 gtggagttgg tcaccacggt gtgcatgtcc cccatcgact tggccggggc cagcacctcg
    17041 cccgcgtcga tgccgtcctg gtacttggcg cgctgggcga agaagccgat ggccgggttg
    17101 tccgagaaga tcttctgcca gctcgcggtg agcgtgaccg ccacgtccca ggcgagcggg
    17161 atgcccgtca cccaggccca cttgaggcgg cccgacttga tcagcagcgt ggtgcagacg
    17221 gccagcgcga cggcggccag cagctggttg gcgataccga agagcgggaa gagctggttg
    17281 atgccgccca gcgggtcgtg gacgccgacc cagaggaagt agccccagca gccgaccacg
    17341 atcgccgagg tgatccagac gcccggccac cagctgacgc ggcgcatcgg cttccagacg
    17401 ttgcccaggg tgtcctggag catgaagcgg ccgacccgcg taccggcgtc gacggtggtg
    17461 aggatgaaga gcgcctcgaa catgatcgcg aagtggtacc agaacgcctt catcccggcg
    17521 ccgccgaggg cggccgcgaa gatctcggcc ataccgaggg cgaaggtggg cgcgccaccg
    17581 gtccgtgaca gcagcgagtt ctcctcgacg tccttcgccg cctgggccag ttggtccggg
    17641 gtgatggtga agccgaggtt ggcgaccgcc tccgaggcgc tctgcacggt gtcgccgatg
    17701 acgccgaccg gggcgttgat cgcgaagtac aggcccgggt cgatgatgca ggcggcgatc
    17761 atcgccatga tggcgacgaa cgactcggtg agcatcgcgc cgtagccgat catccggatc
    17821 tgggtctcct tctggaccat cttcggggtg gtgcccgagg agaccaggga gtggaagccg
    17881 gagagcgcgc cgcaggcgat ggtgatgaag acgaacggga agagcgagcc ggagaagacc
    17941 gggcccgcgc cgctggtcgc gaaggaggtg acgccgtcca tcttcagcgt cggcatcgcg
    18001 acgatgacgc agaccgccat cagcacgatc gtgccgacct tcatgaaggt ggagaggtag
    18061 tcacgcgggg cgagcagcat ccagaccggc agcaccgagg cgaagaagcc gtagaccacc
    18121 atccagatga ccagggtgcc cggctccagg gtgaagaagt ccgccatgga ggactcggcg
    18181 acccagccgc cgcccacgat cgccagcagc agcagggcga cgccgaggac ggagacctcg
    18241 gtgaccttgc cggggcgcag cgtgcgcagg tagatgccca tgaagagggc gatcgggatg
    18301 gtcatgccga tggagaagac accccacggc gaaccggcca gcgcgttgac gatgacgagg
    18361 gccagcaccg ccagcaggat gatcatgatc atgaagaccg cgatcagggc ggcgacaccg
    18421 ccgaccgggc cgatctcgtc ccgggccatc tggccgagcg aacggccgtt gcgccgggtg
    18481 gagaagaaga gggtgaccat gtcctggacg gcaccggcga agatcacgcc cgccacgatc
    18541 cagatggtgc ccggcaggta gcccatctgg gccgccagga tcgggccgac cagcgggccc
    18601 gcacccgcga tcgccgcgaa gtggtggccg aagagcaccc ggcggtcggt cggctggaaa
    18661 tcgaccccgt tgtccaggcg ctccgccggg gtggcccggt tcttgtcgac cttcaggacc
    18721 ttgttggcga tgaaccgcga gtagaagcgg tacgcgatgg cgtacgagcc gagggccgcc
    18781 gccagcatcc agatggcgga gatctcctcg ccccgggaga gcgccagcac gctccaggcg
    18841 atggcgccga ccacggcgac cagcgaccag acggcgatgg atttggcgga cagcttccgg
    18901 tttccggagg cgggtggagc cggctcggcc atgatggtcc cctcacatga gcgtaggtgg
    18961 aaacacctgc gctgaactcc tgcaatgcgt cggaaatgta ggcgacgggt ccgggctttg
    19021 acaccccctg tccgcgtatc ggaacgacaa cgacttcacc gccggcgcaa ccgtgtgccg
    19081 tggccgccgc gtctccgtcc cttacgcacg cctccccgcg catttgtccc ccgtgtggcg
    19141 agcgccccgc ccgagtggcc cttcaccgat cgccccccaa ccgtgacctt ccgccggtga
    19201 ggtgcgtacc ccgcatcgcc cggcggtcat gcgcggaaaa gcacacacgt acgagcgaat
    19261 tgcccggcgg gggtcaggcg ggggcgagtg gggtcattac cgggtggccg gaaagtgagg
    19321 gtcgatttcc cgccaagtgc ccttgtgttt cccgtcggcc cgtatgccgg acatgggaaa
    19381 gggcggcatc cccggtgaag gggtgccgcc ccgctgtccg tccgcgcgcc ggtcctactc
    19441 gacgggccgc ttcagccgcg ccaggaactt gtaccggtcg ccccggtaga ccgagcgcac
    19501 ccactccacc ggcgcgcccg actcgtcgcg ggagtggcgg gagagcatga gcatcggcag
    19561 gcccacgtcg gtggcgagca gggccgcctc gcgcggggtg gcgagcgagg tctcgatggt
    19621 ctcctcggcc tcggccgggc gcaccccgta gacctcgtag agcgccgtgt agagagaggt
    19681 gtacttgacc agggagcggc gcagggcggg gaagcgcttg gcggagaggt gggtggtctc
    19741 gatcgccatc ggctcgccgc tggccagccg gagccgctcg atgcgcagca cccggccgcc
    19801 ggcggtgatg tcgagcaggg aggcgaggga gtcgtcggcg gtgatgtagc cgacctccag
    19861 cagctgcgag gtgggctcca ggccctgggc gcgcatgtcc tcggtgtagg aggtcagctg
    19921 gagcgcctgg gagacctttg gcttggcgac gaaggtgccc ttgccctgga tgcgttcgag
    19981 ccggccctcg accaccagct cctggagcgc ctggcgcacc gtggtccgcg aggtgtcgaa
    20041 ctcggcggcg agcgtacgct cggggggcac ggaggttccc ggcggcagcg tccgcgtcat
    20101 gtcgagcaag tgccgcttga ggcggtagta cttgggcacc cgcgtggccc ggaccggact
    20161 ggtcggctcg gtggcgggtt cgccggccgt ccgggtcctc gtaccgcccg cgtccgtcgt
    20221 catgctccgc ccctccggct cctgtgctgc tgccgtcacc ggctcctccg tctgtcgcgg
    20281 atcacatcgt ggcacggccg gtgatcgccg gtccggactc cctcaggtgt cggtccgata
    20341 acggacgcga ctgcccttct tatacaccct tgacacccct aaaggtctag gccaagctcc
    20401 ggcttactgg tctacaccat taaagaccag atcccagtcc cacggcagta actcgtcttc
    20461 gatgtcatcg ctgcgggtgg ggggtagagg gttccctgag gagggtgacg tgaagcgcaa
    20521 gctcattgcg gccatcggtg tcgctggcat gatggccggt ctcgcggcgt gcggggactc
    20581 ggagacggcg agcaacgcca agcccgagga ccgcaaggaa aacctgaccg tctggctgat
    20641 ggtcgacgcc cagagcacct ggccggagct ggtcaaggac gtcaacgcgc agttcaagaa
    20701 gaagtacccc aatgtcaagg tgaacgtcca gtaccagggc tgggccgaca aggccaagaa
    20761 gctcgacacc gccctcggcg gggacaagtt cccggacgtc gtcgagctcg gcaacaccga
    20821 gacgatgcag tacatcctca acggcgccct cgccgagatc gaccccaaga agtatgagaa
    20881 ctcggacacc tggatccagg gcctcaccga cacctgcacc ttcgagggca agcagtactg
    20941 cgtgccttac tacgccggtg cccgcgtcgc ggtct
//
