LOCUS       NZ_JAEACL010000003     20416 bp    DNA     linear   CON 23-MAR-2024
DEFINITION  Bacillus halotolerans strain Nss14 C3PK5, whole genome shotgun
            sequence.
ACCESSION   NZ_JAEACL010000003
VERSION     NZ_JAEACL010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus halotolerans
  ORGANISM  Bacillus halotolerans
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 764373)
  AUTHORS   Douka,D., Papadimitriou,K., Venieraki,A. and Katinakis,P.
  TITLE     Genome sequence of Bacillus halotolerans PK5 (Nss14)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 764373)
  AUTHORS   Douka,D., Papadimitriou,K., Venieraki,A. and Katinakis,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-NOV-2020) Crop Science, Agricultural University of
            Athens, Iera Odos 75, Athens 11855, Greece
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 60.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016767285.1-RS_2024_03_23
            Annotation Date                   :: 03/23/2024 01:56:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,125
            CDSs (total)                      :: 4,048
            Genes (coding)                    :: 3,918
            CDSs (with protein)               :: 3,918
            Genes (RNA)                       :: 77
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 55
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 85 of 130
            Pseudo Genes (incomplete)         :: 68 of 130
            Pseudo Genes (internal stop)      :: 30 of 130
            Pseudo Genes (multiple problems)  :: 45 of 130
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:29:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 36617
            Orig. end                         :: 57033
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAEACL010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20416
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..20416
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20416
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:15416](+)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..15416
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     gene            complement(206..1036)
                     /locus_tag="I5F14_RS03950"
                     /old_locus_tag="I5F14_03955"
     CDS             complement(206..1036)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010331462.1"
                     /locus_tag="I5F14_RS03950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_03955"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_202646884.1"
                     /transl_table=11
                     /translation="MLSIGEFSKICKVSTKTLRYYDEIGLIHPEDINPENGYRYYSIRQ
                     LKEMLLINRLKSYHFSLEEIKTILDLEKDQAEEKLGSALQRKRKEVQEKINAYEYTLTQ
                     LNLDILRAEKGKPMMSWLDDIEVVLAETQPMNILYLRKMMSSHDYALGYEKYFSRLYER
                     IAVDKLTLLGTPMTIYHSPEYNPAGNDTEFAIPIEETARATRDLRGGLCAKSVLKGSYS
                     ELTSVYAKLREWVEDEGYELAQSPYEVYVTDHQQAGVPEDIVTEVYFPIKKKER"
     gene            1171..2148
                     /locus_tag="I5F14_RS03955"
                     /old_locus_tag="I5F14_03960"
     CDS             1171..2148
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388081.2"
                     /locus_tag="I5F14_RS03955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_03960"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_202646885.1"
                     /sec_met_domain="PF00561 (E-value: 1.3e-06, bitscore: 23.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVVKIFFGSIGALILLAAVSVFIYHHYQLNKEAALLKEKG
                     TLVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSDVYDDDRDIDTILEQTRKALLQSGNKPPYILMPHSISGIEAIYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGIDRLKMRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSMNLPAPKETPVLILDAVSDQNRNSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKFSMEFIRKVR"
     misc_feature    1173..1184
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.13"
                     /tool="antismash"
     gene            2148..2819
                     /locus_tag="I5F14_RS03960"
                     /old_locus_tag="I5F14_03965"
     CDS             2148..2819
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388082.1"
                     /locus_tag="I5F14_RS03960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_03965"
                     /product="response regulator transcription factor"
                     /protein_id="WP_059353014.1"
                     /transl_table=11
                     /translation="MKSYHILIVEDDVMIGDLLQKILQREGYHVMWKTDGADVLSVIQK
                     ADLVIMDVMLPGEDGYQMSKKIKDLGLNLPIIFLSARNDMDSKLQGLKIGEDYMVKPFD
                     PRELLLRMKNMLEHHYGTFTQIKHLYIDADTKKVFNGSLHHEVLFTAIERKIFFYLYEN
                     RNNILTKEHFFDYLWQLEDRNPNIVNVHIKKIRAKINDLAGEIIENIYGEGYRLNTVVK
                     K"
     gene            2816..3808
                     /locus_tag="I5F14_RS03965"
                     /old_locus_tag="I5F14_03970"
     CDS             2816..3808
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223675.1"
                     /locus_tag="I5F14_RS03965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_03970"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_202646886.1"
                     /transl_table=11
                     /translation="MKLKTKYQLLLCTAVISVPVLLLAVSILMSVIYDSVFKPINHGMP
                     FHRSFAYPAMLAVFLLSLLLLAFLFSKSIHSLLRKINLLNQTIRHLASDQKVPDKIEVK
                     RADEIGELIKSVNLLIERTIYRELELRQQEEVKKELLQKLRHDMNTPLTALRLQLFYLE
                     GQCDDQAVFESLYQQIHYIAELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMNGIELHFKPADQDVIWMSNVLWMQRLFDNIFQNTLKHAKADKMEVTIEDGTVSIR
                     DDGIGFDQNKNSDGLGLKIIDDICRLLHMTYHLKTDKTGTHFNFKNDKM"
     gene            complement(3971..4861)
                     /locus_tag="I5F14_RS03970"
                     /old_locus_tag="I5F14_03975"
     CDS             complement(3971..4861)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223677.1"
                     /locus_tag="I5F14_RS03970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_03975"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_202646887.1"
                     /transl_table=11
                     /translation="MNLHALRLFYTVAEEGNVTGAAKKLNISQPAVTAQIKKLEKEIGL
                     TLFHPRGRGVFLTQTGLQLAKQAKRLFSLQHEIESYLEHIKEGSVGTLHIVTTSLPANF
                     LLPKWISRFKREYPDVDVEITTVNSTEAINQLVNYKADIGIIGGNRTFNKHISSSLLLE
                     DEMLFISNNIHKYAEQTISLAEMVKEPFVFREEGSFSRELLFSLCNLFNVNKPCTGLQM
                     NGLNETINTVIEGYGVTFVSFLEVNSYLSRGDVKRINVEHVEVTNPISLCWRNDDVIST
                     TAFNFIELIRTDKME"
     gene            5001..6302
                     /gene="thrC"
                     /locus_tag="I5F14_RS03975"
                     /old_locus_tag="I5F14_03980"
     CDS             5001..6302
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PALP"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223678.1"
                     /locus_tag="I5F14_RS03975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_03980"
                     /product="threonine synthase"
                     /protein_id="WP_202646888.1"
                     /sec_met_domain="PALP (E-value: 2.1e-55, bitscore: 183.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLICIDCGQEMSPDDFKYQCSCGGLLDIVHDFSQYDPDFLKHVF
                     HERLSERMSVFASGVWRYKELIYPDLPVESIVTKYEGNTGLYRSEMLSTYTGVRHVYVK
                     AQSENPSGSFKDNGMTVAVSHGKHLGYEKYACTSTGNTSSSLGMYAALANASSYVFVPD
                     KEISMNKVLQTAAYGGNVFSIPGTYDDGIKFLEKYSSDFGFYICNSINPFRIEGQKSII
                     YEIAQYLDWQLPDWIIVPGGALSNATALGKGLRDLYALHFIDKIPRVAIIQAEGASPFH
                     QMISEKKETLDPEPFPYTRASALNIGNPPSWKKAKKVLDDTNGITVSVTDEDILDAKAI
                     IDRTGVGCEPASASTAAGLRQLRSQHIIDKDESVLCILTGNILKDTGALHDYHFGKELN
                     GKFKNNIKSVELQFEKVKSAMESIRDVNGLLKNH"
     gene            6423..7565
                     /locus_tag="I5F14_RS03980"
                     /old_locus_tag="I5F14_03985"
     CDS             6423..7565
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223680.1"
                     /locus_tag="I5F14_RS03980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_03985"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_237728864.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 7.3e-07, bitscore:
                     24.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 2.6e-10, bitscore:
                     35.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTSTERLNECKNYDQIESFDEYPVNGCIEIRALELHETYRFHTI
                     IAMSEYDLLRAGKLRTHLGVEGQSYESALLFRDKVLMKQRLEEAGIPVPPYRKIESSVD
                     LYLFVQQFGFPVVVKPIDGSGSVGTKVLKNESDMMEYLSKGLSENMEAETFVDGDMYHI
                     DGMLIDGQMTLNWPSRYINGCLAFQEEQFLASYQLGADNPLTSRLTDIVEKALKALPSP
                     KTTTFHAEVFHTPDDKLVFCEIASRTGGGLIREATQQGFGFDLNEVCVKKQCGLSYDIP
                     NDSQLKRGPKQLSGWILIPPKHGRLVKVPSIPFENWITKQKISAKEGEIFQGASSSVDV
                     VSSYLIKGDSEDVLINRIHQVASWCSENMIWEGQSTWSLK"
     gene            7550..8773
                     /locus_tag="I5F14_RS03985"
                     /old_locus_tag="I5F14_03990"
     CDS             7550..8773
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223682.1"
                     /locus_tag="I5F14_RS03985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_03990"
                     /product="MFS transporter"
                     /protein_id="WP_202646889.1"
                     /transl_table=11
                     /translation="MVSQIKEFFGLHPVIKFLLVGTLVTKAAKSMTTPFLAIYLHQETG
                     EGFGVIGLVIGLGYFATTIGGIIGGTLSDRIGRKSVMLCSIFIWSIVFFLFGIVHTILW
                     FSLLNILSGLCHSFFEPVSKALMVELADSKKRLSIFSLRYLAINVGGALGPLLGTYLGL
                     VSSGTPFIITGAVYLCYALLLLFMMNKLLLKHKRNSKKEFHLSFIVKTLKKDVALRYYI
                     AGGIFLLFSYSQMESTLLQYLNLDFVNGVKIFSILITINAVTVIILQLPLTRLFERYKS
                     MTTISVGTGCCIIGNIGFAFSTGWLTFCISMFILTMGEILCFPSMNVLMDELAPDSMRG
                     AYYGAQNFYNIGEFIGPWLGGMILSLFGGRTIFLVAALSICFALTAYRIGNRKHRFIQF
                     NEAEVMNK"
     gene            8808..9311
                     /locus_tag="I5F14_RS03990"
                     /old_locus_tag="I5F14_03995"
     CDS             8808..9311
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223684.1"
                     /locus_tag="I5F14_RS03990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_03995"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_202646890.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 4.3e-09, bitscore:
                     31.7, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTAERMLSTLTENNYTHFTGVPCSLLKGFFRLLESNETAEKQN
                     ITFIPSIREDSALGVASGMYLGGKKCVMLMQNSGLGYCLNVLTSFNFIYDIPILLLISW
                     RGAYGNDAVEHDIIGEKLTDLLHSVDIPYKELDDENAEDTLVEALFLIEKTNRPVAILI
                     KDEI"
     gene            9323..9883
                     /locus_tag="I5F14_RS03995"
                     /old_locus_tag="I5F14_04000"
     CDS             9323..9883
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223687.1"
                     /locus_tag="I5F14_RS03995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04000"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_202646891.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-14, bitscore:
                     49.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKHDAIQLVLEQFPSAYLVSTCGHISRDLYNIDDRAKNFYMVGS
                     MGMAAPVGLGLSAVYPDVPLVVLDGDGSFLMNMGIITMIGHQKPKNFIHVVLDNGMHES
                     TGGQKTVPLMNVTDIALQVGYKYAVEINSVQESFDLPNEGPALIHIKVEPRSEKIGKRV
                     HWTPQEIVQRFTHEITLENEVSV"
     gene            9880..10890
                     /locus_tag="I5F14_RS04000"
                     /old_locus_tag="I5F14_04005"
     CDS             9880..10890
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223689.1"
                     /locus_tag="I5F14_RS04000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04005"
                     /product="aldolase"
                     /protein_id="WP_202646892.1"
                     /sec_met_domain="HMGL-like (E-value: 1.6e-40, bitscore:
                     134.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTQVIDCTLRDGGNFNNWFFSAEDIGQIIRNLDKANVNIIEIGY
                     VGGSGSNKEKSVGSLANCTPELLDELPKMSHSQLAAMVVPSVCELHLLDNLNPQQIPWM
                     RVASYPHNAEDALPYIEYLKNQGFHVSFNVMAASYIEERDVAELAKKAHAFGADVFYMA
                     DSFGNLTPDGVKNRVAAACDQADCPVGFHGHNNLGLAFANALAAMDAGAAFIDTSLCGM
                     ARGAGNLPTEQFISALHHWDKFHIPYKLDPILTAAEYVLSSILSSPMRISTPEIISGIS
                     NIHYYFYDLVIQKCQEVNLDPLEVSTLLGKSLPKKVDMSSIESVIDQNFRQESAK"
     gene            10887..11777
                     /gene="aepX"
                     /locus_tag="I5F14_RS04005"
                     /old_locus_tag="I5F14_04010"
     CDS             10887..11777
                     /EC_number="5.4.2.9"
                     /GO_function="GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="aepX"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223692.1"
                     /locus_tag="I5F14_RS04005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04010"
                     /product="phosphoenolpyruvate mutase"
                     /protein_id="WP_202646893.1"
                     /sec_met_domain="phosphonates (E-value: 7.2e-133, bitscore:
                     437.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates-like (E-value: 5.1e-143,
                     bitscore: 470.5, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2e-70, bitscore:
                     232.5, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAKKLRELLYSDQVVRVMGAHNGLSAKLAEQAGFDAIWASGLEI
                     SASYAVPDANILTMTENLQAAIGMNESTSIPIICDCDSGYGSVNNVIRMVKEYERNGIA
                     GICIEDKLFPKLNSFVKGSQKLASIDEFSNKIRAAKDVQRNPDFVVIARVEALIAGQGL
                     EEALKRAHAYEAAGADAILIHSKENQPNEIKEFVKQFTGAVPIVIVPTTYPHITVDEMK
                     PLGIDMVIYANHGLRSSIKAMQETFSQILLDGNTVGVEDHIVPMKTVFELQGMYDMRKQ
                     EDMYNSGASVTSTIK"
     gene            11801..12889
                     /locus_tag="I5F14_RS04010"
                     /old_locus_tag="I5F14_04015"
     CDS             11801..12889
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223694.1"
                     /locus_tag="I5F14_RS04010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04015"
                     /product="hypothetical protein"
                     /protein_id="WP_202646894.1"
                     /transl_table=11
                     /translation="MMSDQYHIVSLAYLHSKINFFIEPSLSLDHVFDFFSTHFFINKGR
                     HEEDRLADVYITPHKEEVQAIDFHNGEDIYIRKSATEYFTIPCKRVTVEGIEYVKCTKT
                     DTILSFDRENKKIIISTQLQHTEQDELVFIEFIRDLVLKNEENYGVAVVHATSALKDDK
                     ATLIIGSKGKGKSTLLLELVSKHGYKLISGDKTFLWIEDGKLRAAGWPDYPHLGLGTLS
                     KYPEFVEYFGLSHQIESVKENLWSTEHKMAIDPVFFKKVIPFAERGESFLVESMIYPDL
                     FPSTDCEIKRVSNHEELIVPHIERIFTEGNNMWNHFIRPVHQNELERKINQCLELAGKL
                     SGFEVSGSGVLEGSGFSERYAL"
     gene            12924..13322
                     /locus_tag="I5F14_RS04015"
                     /old_locus_tag="I5F14_04020"
     CDS             12924..13322
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223695.1"
                     /locus_tag="I5F14_RS04015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04020"
                     /product="YjbQ family protein"
                     /protein_id="WP_202646895.1"
                     /transl_table=11
                     /translation="MVEITIQSKGFNQSYDITEQVTDSLSQLEPSSGVAKVCVTGSTVG
                     LTVMRYEPGTIQDLLQCLESIASKNKQYEHFNTTGDPNGFSHVWSSMMGTSVMVPYKNH
                     KLACSESHRIVLFDFDLREAERKIYVDR"
     gene            13424..14503
                     /locus_tag="I5F14_RS04020"
                     /old_locus_tag="I5F14_04025"
     CDS             13424..14503
                     /NRPS_PKS="Domain: Aminotran_5 (1-299). E-value: 2.1e-40.
                     Score: 130.7. Matches aSDomain:
                     nrpspksdomains_I5F14_RS04020_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223698.1"
                     /locus_tag="I5F14_RS04020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04025"
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="WP_237728887.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.5e-29, bitscore:
                     98.6, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHHRSRQMEDIINEINRELPDLFLTKQDIYILLSSGTGAMEAAV
                     SNSFNRGDKVLVVSNGYFGERFTDICTVFGLEVVTVNAPWGTSVNIEEVERAYKQHPNI
                     KGVLAVYSETSTGAVNDVQAIGALFRDTDVLVIVDAISGLISHELSMDDWGLDIVLAAS
                     HKGFMMPPGLAFVAISPKAWKLIDDVQPSTYYFSFKRFKKFYPMAPSSPGVSLLLALKK
                     SLDLLKAEGLSNATRRHARIARATQKGLEALGFHLFVQSPHVRSHTVTAALTPSGIDAA
                     LLLQKLNKEYGLTITGGQGEFKGKMIRIGHIGAVDEIDLFGIFGIIELVLTEMGYQVQP
                     GTSMTALSEALGAEVIQNA"
     aSDomain        13427..14320
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I5F14_RS04020_Aminotran_5.1"
                     /evalue="2.10E-40"
                     /label="I5F14_RS04020_Aminotran_5.1"
                     /locus_tag="I5F14_RS04020"
                     /protein_end="299"
                     /protein_start="1"
                     /score="130.7"
                     /tool="antismash"
                     /translation="IHHRSRQMEDIINEINRELPDLFLTKQDIYILLSSGTGAMEAAVS
                     NSFNRGDKVLVVSNGYFGERFTDICTVFGLEVVTVNAPWGTSVNIEEVERAYKQHPNIK
                     GVLAVYSETSTGAVNDVQAIGALFRDTDVLVIVDAISGLISHELSMDDWGLDIVLAASH
                     KGFMMPPGLAFVAISPKAWKLIDDVQPSTYYFSFKRFKKFYPMAPSSPGVSLLLALKKS
                     LDLLKAEGLSNATRRHARIARATQKGLEALGFHLFVQSPHVRSHTVTAALTPSGIDAAL
                     LLQKLNKEYGLTITGGQ"
     gene            14496..14753
                     /locus_tag="I5F14_RS04025"
                     /old_locus_tag="I5F14_04030"
     CDS             14496..14753
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223700.1"
                     /locus_tag="I5F14_RS04025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04030"
                     /product="glutaredoxin domain-containing protein"
                     /protein_id="WP_202646896.1"
                     /sec_met_domain="GST_N_3 (E-value: 4.5e-08, bitscore: 28.9,
                     seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKLYQREPCPYCKPVREKLTELNVTYINVNLPKDRTLRTELIEK
                     TGVPYIPALIDEEDNVVIPGKLEYNQHVLDYIEKKFGQNR"
     gene            14769..15416
                     /locus_tag="I5F14_RS04030"
                     /old_locus_tag="I5F14_04035"
     CDS             14769..15416
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Metallophos_2"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223702.1"
                     /locus_tag="I5F14_RS04030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04035"
                     /product="metallophosphoesterase"
                     /protein_id="WP_202646897.1"
                     /sec_met_domain="Metallophos_2 (E-value: 9.7e-12, bitscore:
                     40.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYAFITDIHGKRNNLEKVLEHIQAFSSIHEIICLGDVFEVKVPK
                     KDLKDFQFQSIEQVLDLDWELIDLLKGIRVIKGNQEERILSLIPEKEIPIDFYNFLTHM
                     PLDIYLTPMVRLTHGHTFDWMEEEDYWRPSHIHYWSRPWIFYGHNHQNVLFEVQEKKNH
                     PYYERKHIINGKPITLDAASRYLINIGDMKYDHPSWMLLDTLENQITYNILY"
     gene            15433..16674
                     /locus_tag="I5F14_RS04035"
                     /old_locus_tag="I5F14_04040"
     CDS             15433..16674
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223704.1"
                     /locus_tag="I5F14_RS04035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04040"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_202646898.1"
                     /sec_met_domain="ATP-grasp (E-value: 2.4e-06, bitscore:
                     22.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRILLINSDKPEPIQFFQKDKETNDTINISVITRSCYAPLYSHW
                     TDHVYIVDDITDVTVMKSLMLEILKVGPIDHIVTTTEKSILTGGFLRSYFGIAGPEFET
                     SLYMTNKLAMKTKLKMEGIPVADFLCLSQVEDIPAAGEKLGWPIIVKPALGSGALNTFI
                     IESLHHFESLYSTSDGLGELKKNNSLMIVEKCIEMEEFHCDTLYADGEILFVSISKYTV
                     PLLKGMAKIQGSFILSQDDPLYAEILELQKSVAQAFRITDGPGHLEIYRTPSGELIVGE
                     IAMRIGGGGISRMIEKKFNISLWESSLNASIGKDPNLMVNPIEGTVGYFSLPCRNGTIK
                     EFTPIEDWEKLDGIMEVELLYQEGDVVDEKQSSSFDLARLYFCLENENEVQHLLALVKQ
                     TYYLHVTEDHMMNQ"
     misc_feature    complement(16799..16811)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.18"
                     /tool="antismash"
     misc_feature    17016..17029
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.67"
                     /tool="antismash"
     misc_feature    17044..17058
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.23"
                     /tool="antismash"
     misc_feature    complement(17089..17103)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            17159..18547
                     /locus_tag="I5F14_RS04040"
                     /old_locus_tag="I5F14_04045"
     CDS             17159..18547
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388088.1"
                     /locus_tag="I5F14_RS04040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04045"
                     /product="amino acid permease"
                     /protein_id="WP_044162131.1"
                     /transl_table=11
                     /translation="MENKELKRGLSARHIQMIALGGTIGVGLFMGSASTISWTGPSVLL
                     AYAICGIFIFFIMRAMGEMLYVEPSTGSFATFGHQYIHPLAGYMTAWSNWFQWIIVGMS
                     EIIAVGSYMKYWFPDLPAWIPGIVAMAILGAANLISVKSFGEFEFWFAMIKIVTIILMI
                     IAGIGIIFFGFGNGGDAIGLSNLWSHGGFFAGGFSGFFFALSLVIAAYQGVELIGITAG
                     EAKDPQNTLRNAIQSIIWRILIFYIGAIFVIVTVYPWDELNSLGSPFVSTFSKVGITAA
                     AGIINFVVITAAMSGCNSGIFSAGRMLYTLGVNGQAPKFFAKISRNGVPLYGTIAVLIG
                     LAVGVVLNYVAPPKIFVYVYSASVLPGMIPWFIILISHLGFRKAKGAALDKHPFKMPFA
                     PFTNYLTIAFLLMVLVGMWFNDDTRISLIVGVIFLALVVISYYAFGIGKRVQADLTKRN
                     QAAE"
     gene            18659..18907
                     /locus_tag="I5F14_RS04045"
                     /old_locus_tag="I5F14_04050"
     CDS             18659..18907
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388089.1"
                     /locus_tag="I5F14_RS04045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04050"
                     /product="sigma-G-dependent sporulation-specific
                     acid-soluble spore protein CsgA"
                     /protein_id="WP_010332841.1"
                     /transl_table=11
                     /translation="MDVTLGYLRESLSNHLENEVCLRICKKMLAKRYANEEEFVKDLDD
                     DEMSYLNQVLEKEIKYAQDEQDQKRAKELNEVYELLL"
     gene            18925..19116
                     /locus_tag="I5F14_RS04050"
                     /old_locus_tag="I5F14_04055"
     CDS             18925..19116
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388090.1"
                     /locus_tag="I5F14_RS04050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04055"
                     /product="DUF5370 family protein"
                     /protein_id="WP_202646899.1"
                     /transl_table=11
                     /translation="MGAIERSGYTFQPESSVVRQNGAIHVYHHGEFVEEIEFEFNGDYP
                     DHDLIEELVNHYCFEHDI"
     gene            complement(19147..19956)
                     /gene="blaOXA"
                     /locus_tag="I5F14_RS04055"
                     /old_locus_tag="I5F14_04060"
     CDS             complement(19147..19956)
                     /EC_number="3.5.2.6"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="blaOXA"
                     /gene_functions="resistance (resist) ClassD"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388091.1"
                     /locus_tag="I5F14_RS04055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I5F14_04060"
                     /product="class D beta-lactamase"
                     /protein_id="WP_202646900.1"
                     /transl_table=11
                     /translation="MKKWIYAFLVLVIAVTGGLSVHAKAPSNETKKHLNVSRINVDKEF
                     KDTDGTFILHDLEKDKTFVYNKERANKRQTPQSTFKVTNALIGLQVKAVRDEYDVKRWD
                     GVKREFESWNRDHTLGSAMRESAIWYYQALARDIGEKRMKTWLHTLSYGNEDISGGIDQ
                     FWLQSSLTISPLEQEAFMEKLYKEKLPFDKTVMKTVKRMMIQEEGDHYTLYGKTGTRLT
                     DMGLGWFVGFIKTEHGSYTFVTNVDDSGTTAKNITIDILKKYGLITS"
ORIGIN
        1 gttactgatg ctacatgatg cgtatcattc ggtccatagc tatgataata gcgctcaaag
       61 gcgatgtatc cattttttac aaccacaata ccgtttatat tgctgtattt ggactttatt
      121 ttagggtcaa gcttagacag tttttcggtg tccatcccta aggctgccgg gtctgcagtt
      181 ggccagtcgt ttctttgcat gacagttacc tctctttttt ctttattgga aaatacactt
      241 cagtcacaat atcctctggg acaccagctt gctggtgatc ggttacgtac acttcatagg
      301 gggattgtgc caattcatag ccttcatctt cgacccattc tctcagctta gcgtatacgg
      361 atgtcaattc tgaataggag ccctttaata cagactttgc gcataggcct ccgcgtaaat
      421 ctcttgtagc tctagcagtc tcctctattg gaatcgcaaa ctctgtatca ttgccagcag
      481 ggttgtattc agggctgtga taaatggtca tgggcgtgcc gagcaaggta agtttatcaa
      541 ccgcaattct ttcatatagc ctgctaaaat atttttcgta tcctagggca tagtcatgac
      601 tgctcatcat tttgcgtaaa tacaggatgt tcattggctg ggtttcagca agtactactt
      661 ctatatcgtc aagccatgac atcattggtt tgcctttctc tgcacgcaga atatcgaggt
      721 tcaattgggt aagcgtatat tcataagcat tgatcttttc ctgtacttct tttctttttc
      781 gctgaagggc agaaccaagc ttttcttcag cctgatcctt ttccaaatcg agaatggttt
      841 tgatttcttc cagagaaaaa tgatacgact ttaaacggtt aatcaagagc atttctttca
      901 gctgcctgat agaataatat cgatatccat tttcaggatt aatgtcttcg gggtggatga
      961 gtccgatttc atcgtagtat cgcaatgttt ttgttgatac tttgcatatc tttgaaaatt
     1021 caccgatcga cagcaagcga tcacctccat gctccaaatg tacacctttc cgtaagggca
     1081 aagtcaaata tgaaaataaa actgttccaa agttaatcag ttatttattt tcatgtcgta
     1141 tcctttctgt atcagggaaa ggagcatcat atgaaaacgt tatggaaagt cgtaaaaatc
     1201 ttttttggca gcataggcgc tttgattttg cttgcagccg tctcggtttt tatctaccac
     1261 cattaccagc taaataagga agcagcactc cttaaagaaa aaggtacatt agtcgatgtt
     1321 gacggtaaaa aaatgaatgt gtatcaagag ggaagcggga aggatacgtt tgtgtttatg
     1381 tccggttcgg ggattgcggc gcctgcttat gagatgaaag ggttgtacag caagttttca
     1441 aaagaaaaca agattgctgt agtggatcgt gcgggctatg gctacagcga cgtgtatgat
     1501 gatgacaggg atattgatac aatactagaa cagacgagga aagcgcttct gcaaagcggg
     1561 aataagcctc cttatatttt aatgcctcat tccatatctg ggattgaagc gatatattgg
     1621 gcgcagaaat atcctaagga gatcaaggcg attattgcga tggatattgg attgcctcag
     1681 cagtatgtca cgtataaatt gagcgggatt gacagactga aaatgagagg atttcatctg
     1741 ttaacttcga ttggttttca tcgatttatg ccttccgcag tatataatcc tgaggtgatt
     1801 cggcagtcgt ttttaactga tgaagaaaaa gaaatctata aagccattaa ttttaagcaa
     1861 ttttttaatg ctgatatgga gcatgagctt ttacagtctt atcaaaatgg cagcaaatct
     1921 atgaatttgc cggcgccaaa agaaaccccc gtcctcattt tagatgcggt ctctgaccaa
     1981 aatagaaatt caaagtatgc catacaaaac cgaaaagatt atgaagcgtt tgcggctcaa
     2041 tttaatacag ccgatataaa ggaactaagg ggaacacaca gtatttattt atatcagccc
     2101 gatcaaatat ataaattttc catggagttt ataagaaagg ttcgctaatg aagagttatc
     2161 atattttaat cgtggaagac gatgtcatga ttggtgatct gctgcagaag attttgcagc
     2221 gtgagggata tcatgtgatg tggaaaacag atggagcgga tgtgctttcg gtgattcaga
     2281 aggcggattt ggtcattatg gatgtgatgc tgccgggtga ggacgggtat caaatgtcta
     2341 agaaaataaa agatttgggg ttaaaccttc ctattatttt tctgtccgcc cgcaatgata
     2401 tggacagcaa gcttcaaggg ttgaaaatcg gcgaggatta catggtaaag ccttttgatc
     2461 cgagagagct gctgctgaga atgaaaaata tgcttgagca tcattatggc acctttacgc
     2521 aaatcaaaca tttgtatatt gatgcagaca ccaaaaaggt attcaatggg agtttgcacc
     2581 atgaagtgct gtttaccgcg attgagcgga aaatattctt ctatctgtat gaaaacagaa
     2641 acaatatttt aacaaaggaa catttctttg attatctatg gcagcttgaa gacagaaatc
     2701 cgaatatcgt gaatgtgcac attaaaaaaa tcagagcgaa aattaatgat ttagcgggtg
     2761 agatcattga aaatatctat ggagaagggt atcggctgaa taccgttgtg aagaaatgaa
     2821 gctaaagaca aaatatcagt tgttattatg tacggccgtc attagtgttc cggtactgtt
     2881 gctggcggtt agcattttga tgtcggtgat ttatgacagc gtgtttaaac cgatcaatca
     2941 tggcatgccc tttcacaggt cttttgcgta tccggcaatg ctggctgtat ttttattatc
     3001 acttttattg ttagcttttt tattttcaaa atcgattcat tctctgctgc gtaaaatcaa
     3061 tctattgaat caaaccattc ggcatctggc gagtgatcaa aaggtgcctg ataaaataga
     3121 agtgaaacgc gctgatgaaa tcggggaact gattaagtcg gtcaatttgt taattgaacg
     3181 gacgatatac cgtgaactgg aactgaggca gcaggaggaa gtgaaaaagg agcttttgca
     3241 aaaactgcgt catgacatga atacaccttt aacagctctc aggctgcagt tattttattt
     3301 ggagggccaa tgtgatgatc aggccgtatt tgaatcattg tatcagcaaa tccactatat
     3361 cgcggaatta accaatgaat tcaatttata ttccgctgag acgttagaaa gttcttatat
     3421 tgtaaatgaa gaagtgcgtc taaacgagct gttagagaca gccgtgaaaa agtgggatta
     3481 tttatatagt atgaatggaa ttgaattgca ctttaagccg gcagatcaag atgtgatatg
     3541 gatgagcaac gtgttatgga tgcaaaggct gtttgataat atttttcaaa atacattaaa
     3601 gcatgcaaaa gctgataaga tggaagtcac gatcgaagat ggcactgttt ctattcgcga
     3661 tgatggtatt gggtttgacc agaataagaa cagtgatggg cttgggctaa agattattga
     3721 tgatatatgc aggcttcttc atatgacgta ccatttaaaa acagataaaa caggaactca
     3781 tttcaatttc aaaaatgata aaatgtaaac cccttagact gaatatgtaa ggggtttttc
     3841 agcacgaaga aaaactgctc attacatata aaattaaaag agtgcaagtg atatgatgag
     3901 ggcgatgaat tcatataata aatagaaggt atttaggatc ttttgggatt gattcgatag
     3961 agagataaga ttattccatt ttatctgttc ttattagttc aataaaatta aatgctgttg
     4021 tcgagatgac atcatcattt ctccagcata gcgaaatagg gttagtaacc tctacatgtt
     4081 ccacattaat tcttttcaca tctcctcttg ataaataact attgacttca aggaaagaaa
     4141 caaatgttac gccatatcct tctatgacag tgttaatggt ttcatttagt ccgttcattt
     4201 gtaatccggt acatggctta ttcacattga aaaggttgca taaagagaac aataactccc
     4261 tagagaagct cccttcctca cgaaaaacaa acggttcttt taccatttcc gctagcgaga
     4321 tggtttgttc tgcatattta tgtatgttat tagagataaa taacatttca tcctccaata
     4381 ataatgaact gctaatgtgt ttattaaatg tcctgtttcc gccaataata ccgatgtcag
     4441 ctttataatt tactagttga tttatggctt ctgttgaatt gactgtggta atttctacat
     4501 caacatcagg gtattctctt ttaaatcggc tgatccactt cgggagtaaa aaattagctg
     4561 gtaaactagt ggtcacgata tgcagggttc ctacagagcc ttcttttata tgttccagat
     4621 aggattcaat ctcatgttgg agtgagaata atctttttgc ttgtttagca agctggagac
     4681 ctgtttgcgt taaaaagaca cctcttcctc tagggtgaaa caaagttagt cctatttctt
     4741 tctctagttt tttaatctga gctgttacag caggctgact tatatttagt ttttttgcgg
     4801 cgcctgtgac atttccttcc tcagctacag tgtagaacag tctcaatgca tgaagattca
     4861 ccgttcatct ctccattcat aaaaaataat tatgattata aaatatatat atattagaaa
     4921 tttccatttg tctatattat tataaatcca catataaata ctttataggt ggtgagaggc
     4981 agcttgatgt ctagtaaaaa atgaaactaa tttgtattga ctgtggccaa gaaatgtctc
     5041 ctgatgattt taagtatcaa tgttcttgtg gtggactgct agatattgtt catgattttt
     5101 ctcaatacga tcccgatttt ttaaagcatg tatttcatga acgtctatct gaacgcatgt
     5161 ctgtttttgc aagcggagtt tggagatata aggaacttat ctatccagac ttgcctgttg
     5221 aaagcatcgt tacaaaatat gaagggaaca caggattata ccgctctgag atgctatcga
     5281 catatacagg ggttagacat gtatatgtaa aggcgcaaag tgaaaatccc agcggttcat
     5341 ttaaggataa cggcatgact gttgctgttt cacatggcaa acatttaggt tatgaaaaat
     5401 atgcttgcac gtctactgga aatacttctt catcattggg aatgtatgct gctcttgcaa
     5461 atgcttcctc ctacgttttt gtgccagata aagaaatttc aatgaataaa gtattacaga
     5521 cagctgctta cggtggaaat gtattcagta ttccgggaac ttatgatgac gggatcaagt
     5581 ttttggaaaa gtatagcagt gattttggtt tttatatatg caattctatt aatcctttca
     5641 gaattgaagg ccaaaagagc attatttatg aaatcgctca atatctagac tggcaattgc
     5701 ctgattggat tattgttcct gggggtgctc ttagcaatgc aacggcttta gggaaagggc
     5761 tccgtgattt atatgctcta cacttcatag acaagatacc tcgggtagcc atcatacaag
     5821 cagagggcgc cagtccattt catcaaatga ttagtgaaaa gaaagaaacc cttgatccag
     5881 aaccatttcc gtatactaga gcttctgcat tgaatatagg aaatcctcct agctggaaaa
     5941 aagcaaaaaa ggtgttggat gatacaaatg gaatcactgt ttctgttaca gacgaggata
     6001 ttcttgatgc aaaagcaata atcgacagaa caggagtggg ttgcgagcct gcctctgcct
     6061 cgactgcagc aggactccgc caattgaggt cacagcacat aatagacaaa gatgaatcag
     6121 ttttgtgtat tttaacaggc aatatcttaa aagatactgg ggctcttcac gattatcact
     6181 ttggcaaaga gttgaacggc aagtttaaaa acaatattaa atctgtcgag ttgcaatttg
     6241 aaaaggtaaa atcagcgatg gagtcgattc gtgatgtaaa tggtttatta aagaatcatt
     6301 aatgaaccaa aagaccgtac aagagaggag taaaagcgat tagcacttta atattgaata
     6361 aaacctcata ttctaaatct ccgtatgatt tatggctgaa ggatttagaa gaacctatcg
     6421 tcatgctaac ttcaactgaa cgattgaacg aatgtaaaaa ctatgatcag atcgagtcat
     6481 ttgatgagta ccctgttaat ggatgtattg aaatcagagc gctggagtta catgaaacat
     6541 atagatttca tacgatcatt gcaatgtctg agtatgatct tttaagagca ggtaaactcc
     6601 gtactcattt aggagtggaa gggcagtctt atgagagtgc attattattt cgggacaaag
     6661 tgttaatgaa gcagcgtttg gaagaagcgg ggattcctgt tcctccttat cggaaaattg
     6721 aatcttcggt tgacctgtac ctttttgtac agcagtttgg ttttccggta gtcgtcaagc
     6781 caatagacgg gtcgggatct gtcggtacaa aggtgctgaa aaatgaatca gacatgatgg
     6841 aatatctatc taaagggctc agtgaaaata tggaagcgga aacgtttgtt gatggtgata
     6901 tgtaccatat tgatgggatg ctgatagatg gacagatgac attaaattgg ccctctcggt
     6961 atataaacgg atgtttggct ttccaagagg aacaattttt agccagttat cagcttggtg
     7021 ctgacaatcc attgacctcc agactaacgg acattgttga aaaagcacta aaggcgctgc
     7081 catcaccaaa aacaactact tttcacgcgg aagtgtttca tactccggat gataagctag
     7141 tgttttgcga aattgccagc cggactggag gtgggttaat acgtgaggct acacagcaag
     7201 gatttggttt tgacttgaat gaggtttgcg tgaaaaaaca atgcggcctg tcctatgata
     7261 ttccaaatga ttcacagctt aaaagagggc cgaaacagtt aagcggatgg attttaattc
     7321 ctcctaaaca cgggcggctg gtcaaagttc cttcaattcc ttttgagaat tggataacaa
     7381 agcaaaagat atctgctaaa gaaggggaga tttttcaagg tgcttcttct agtgtagatg
     7441 tggtatcaag ttacttaatc aaaggggatt cggaagatgt actgattaat agaattcatc
     7501 aagttgcctc atggtgcagt gagaatatga tttgggaagg ccaatcaacg tggtctctca
     7561 aataaaagag tttttcggat tacatccggt cattaagttt ctgcttgtgg gaactcttgt
     7621 cacaaaagca gcaaaatcaa tgacaacgcc gtttttggct atttatctcc atcaagaaac
     7681 aggagagggt ttcggtgtca ttggcttggt tattggctta ggatattttg caactacgat
     7741 aggcggaatc attggcggca ccctctctga cagaatcggc agaaaaagtg ttatgttatg
     7801 ttccattttt atttggagta ttgttttctt tctttttggc attgttcata caattttatg
     7861 gttcagtttg ttaaatattt taagcggtct gtgtcattcc tttttcgagc cggtttcgaa
     7921 agctttaatg gttgaattag cagatagcaa gaagaggctc agtatttttt ctttacggta
     7981 tctggctatt aacgttggcg gtgctttagg tccgctatta ggaacatacc tggggctcgt
     8041 gagcagcgga actcctttta ttattactgg cgcggtatac ctttgttatg ctcttttatt
     8101 attatttatg atgaataaac tgcttttgaa acataaaaga aattcaaaaa aagaatttca
     8161 tttgtcgttt attgtaaaga cgctaaaaaa ggatgttgct cttcgttatt atatagcagg
     8221 cggaatattc ttgttattta gttattctca gatggagagt accttgcttc agtacctcaa
     8281 tcttgatttc gtgaacggcg tgaagatttt ctcaatttta ataaccatta atgctgtaac
     8341 tgtcattata ttgcagcttc cattaacacg gctttttgag agatataaat caatgacaac
     8401 gatttctgtt ggaaccgggt gttgtatcat cgggaatatt ggttttgctt tctcaaccgg
     8461 ttggcttact ttctgtattt ctatgtttat attaactatg ggcgaaatcc tatgttttcc
     8521 atcaatgaat gtattaatgg atgagttggc ccctgacagt atgaggggag cttattatgg
     8581 agcgcagaat ttctataata taggcgagtt tataggcccg tggcttggag gcatgatcct
     8641 cagccttttt ggcggaagaa cgattttctt agttgcagct ttgtcgatct gttttgcctt
     8701 aacagcatat cgtatcggaa acagaaagca tagattcatt caatttaatg aagctgaggt
     8761 tatgaataaa taatcattac ttatttcatg taaggggaga attcgatttg aactcaactg
     8821 cagaaagaat gctgagtaca cttacagaaa acaactatac acattttacc ggagtgccat
     8881 gttcattgtt aaaaggtttt ttcaggctgc tggaatcaaa tgaaactgcg gaaaaacaga
     8941 atattacgtt tatcccttcc attagagaag attcagcttt aggtgttgca tccggtatgt
     9001 atctaggcgg gaaaaaatgc gtgatgctca tgcaaaattc aggcttaggg tactgcttaa
     9061 atgtacttac atcctttaac ttcatatatg acattcctat tttattgctc attagctgga
     9121 gaggggcata cggtaatgat gctgttgaac atgacataat cggtgaaaaa ctcactgatt
     9181 tactccattc agtggacatc ccttacaaag agctggatga tgaaaatgct gaagacacgt
     9241 tagtagaggc gcttttttta atcgaaaaga caaaccgccc tgttgcgata ttaattaaag
     9301 atgaaatata ggaggagtca gtttgaataa acatgacgca attcagcttg ttttagaaca
     9361 gtttccgtca gcatatttgg ttagtacatg cggtcatata agccgtgatt tgtacaacat
     9421 agatgacaga gccaagaatt tttatatggt tggctctatg gggatggctg ctcctgtcgg
     9481 attaggattg tctgccgtgt atcctgatgt tcctctggtt gtgctggatg gagatggctc
     9541 gtttttaatg aatatgggga ttattacgat gatcggccat caaaagccta aaaatttcat
     9601 acatgttgtt ttggataacg gtatgcatga aagtacgggc gggcaaaaga cggttccgct
     9661 aatgaatgta acagatatcg ctttacaggt gggatataag tatgccgttg aaatcaattc
     9721 cgtacaggaa agctttgatt tgcctaacga aggtccggca ctcatccata ttaaagttga
     9781 accacgaagt gaaaaaatcg gtaaaagagt gcattggaca ccgcaagaaa tcgttcagcg
     9841 ttttacacat gaaatcactt tagaaaatga ggtgtcagta tgaatacgca agtaatagat
     9901 tgtacacttc gggacggcgg taatttcaat aactggtttt tttctgctga agacatcggt
     9961 caaattatca gaaacttgga taaagccaat gtgaatatca tagaaatcgg ttatgtaggg
    10021 ggttcgggga gcaataaaga aaaatctgtc gggagtttag caaactgtac acctgaactt
    10081 ctagatgagc tgccgaagat gagccattca caattagcgg cgatggttgt cccatcagtc
    10141 tgtgagcttc atctattgga taatctgaat ccgcagcaga ttccatggat gcgtgttgct
    10201 tcgtatcctc ataatgccga agatgcttta ccgtatattg aatatctgaa aaatcaaggc
    10261 tttcacgtta gttttaatgt aatggcagcc agttatattg aagagaggga cgtggctgag
    10321 ctagcgaaaa aagcgcatgc ttttggtgcg gatgtgtttt atatggctga ttctttcgga
    10381 aatttaacgc cggatggtgt taaaaacagg gtagctgctg catgtgatca ggcggattgt
    10441 ccagttggtt ttcacggaca taacaatctt ggattagcct ttgcaaatgc tcttgcagca
    10501 atggatgcgg gggcagcctt tatagataca tcattatgcg ggatggctcg aggtgcggga
    10561 aaccttccaa cagaacaatt tataagtgca ttacatcatt gggacaagtt ccatatccca
    10621 tacaaactag atcccatttt aactgcagct gaatatgtac tatcttccat tttatcttca
    10681 ccaatgagaa tttccactcc agagattata agcggaatca gcaatatcca ctactatttc
    10741 tatgatttag tcattcaaaa atgccaagaa gtcaatcttg accccttaga agtatcaacc
    10801 ttactcggaa aaagcttacc taaaaaagtt gacatgtctt ccattgaatc agttatcgat
    10861 caaaacttta gacaggagag tgcaaaatga aagctaaaaa attacgtgag ttgttatatt
    10921 ccgatcaagt cgtgagagtc atgggggcgc ataacggttt aagcgctaaa cttgctgaac
    10981 aagccggatt cgatgcaata tgggccagcg gattagaaat ttcggcatct tatgctgttc
    11041 ctgatgctaa tattttgacg atgacagaaa atctgcaagc tgcgatcggg atgaatgaat
    11101 ctacatcaat tccaatcatt tgtgattgcg attctggtta tggaagtgtg aacaatgtga
    11161 tacgtatggt aaaagaatat gagaggaacg gaattgcggg tatttgcata gaggacaagc
    11221 tgtttcctaa attaaacagt ttcgtaaagg gatcgcagaa attagcttct attgatgaat
    11281 tctcaaataa aatcagagcg gcaaaagatg ttcaaagaaa tcctgatttt gttgttattg
    11341 ctagagtaga agctttaatc gcgggccaag gattagagga agcattaaaa agagcccatg
    11401 cttatgaggc agcaggagct gatgccattc tgatccattc aaaagaaaac cagccaaacg
    11461 aaattaaaga attcgtcaaa cagtttactg gagcagtacc tattgtgatt gtacctacga
    11521 catacccgca tataactgta gacgaaatga aaccattagg catcgatatg gtcatttatg
    11581 ccaaccacgg tcttagaagc tctattaagg ccatgcagga gacattttct cagattcttc
    11641 ttgatggaaa tactgttggt gtagaagatc acattgtgcc tatgaaaact gttttcgaac
    11701 ttcaaggcat gtatgacatg agaaaacagg aagatatgta taactccggc gcttctgtca
    11761 ccagtacgat caaataaaat acgagaggag tcattttaga atgatgtctg accaatatca
    11821 tattgtttca ctagcctatt tacattcgaa aatcaatttc tttattgaac cgtcattatc
    11881 attagatcat gtttttgatt ttttcagtac acactttttt attaacaagg gaaggcatga
    11941 agaagatcgt ttggctgatg tttacatcac tcctcataaa gaagaagttc aagcgataga
    12001 ctttcataac ggtgaggata tttatatcag aaaaagtgcg actgagtatt ttaccattcc
    12061 ttgtaaacga gtaactgttg aaggaattga atatgtgaaa tgtacaaaaa cagatacgat
    12121 tctctcattt gatagagaaa acaagaaaat cattatttct acacagttac agcatacaga
    12181 gcaggatgaa ctggttttca ttgagttcat tagagattta gtattgaaaa atgaagagaa
    12241 ctatggggtg gcagtggtgc atgcaaccag cgcgttaaaa gatgacaaag caaccctcat
    12301 cataggttca aaagggaaag gcaaatcaac tttattgctg gaattagtga gtaaacatgg
    12361 atacaagctc ataagcggtg ataagacgtt cctttggatc gaagacggaa agttacgggc
    12421 cgcagggtgg ccggattatc ctcatttggg actcggcaca ctttctaaat atccggagtt
    12481 tgttgaatac ttcggtctct ctcatcaaat tgaatctgta aaagaaaatc tgtggtcaac
    12541 tgaacataaa atggccattg acccggtttt ttttaagaag gttattcctt ttgcagaacg
    12601 aggagaatca tttttggttg agtctatgat ttatcctgat ttattccctt caacagattg
    12661 cgaaattaag cgggtaagta atcatgaaga attgattgta ccgcatatag aaaggatttt
    12721 tacggaagga aacaacatgt ggaaccattt tatacgccct gtacaccaga atgaactgga
    12781 gagaaaaata aatcagtgtc ttgagcttgc gggaaagctt tctggttttg aagtgagcgg
    12841 gtcaggtgtt ttggaaggtt caggattcag cgagagatac gccctgtaat tttcggaaaa
    12901 tagaaaataa aggagaaaat aaagtggttg aaatcacgat tcaatcaaaa ggctttaatc
    12961 aaagttatga tattacagaa caagtaacag actcattatc tcaattagag ccatcttcag
    13021 gtgtagcaaa ggtttgtgta accggcagta cagtaggtct cactgtcatg cgttatgaac
    13081 caggcaccat acaagacttg cttcaatgtt tagaatcaat tgcttcaaaa aataaacaat
    13141 acgagcactt taacacaacc ggtgacccga atggtttttc acatgtatgg tcttcaatga
    13201 tggggacaag tgtgatggtt ccatacaaaa atcataagct ggcttgttcg gaaagccata
    13261 ggatcgtatt atttgatttt gatttaaggg aagcagaacg aaaaatctat gtagatcggt
    13321 aatgaatata tgaggggagt tgtttgagat gaggaagtta cggatggcta cgccgggacc
    13381 tacgcaagtt ccgcaggaca ttttattggc gggagcacag gaaatgattc atcacagatc
    13441 tcggcaaatg gaagatatta tcaatgaaat taatcgcgaa ctcccagatc tttttttgac
    13501 aaaacaagat atttatattt tgttatcttc aggtacgggg gcgatggagg cagctgtatc
    13561 aaactccttt aacaggggag ataaagtctt agtcgtctct aatggttact ttggagagcg
    13621 ttttacagat atctgtacag tcttcggatt agaggtggtc accgtaaacg ctccttgggg
    13681 aacttctgta aatattgaag aagttgaaag agcgtataag cagcatccga atataaaggg
    13741 agtgctcgct gtttatagtg aaacctcaac aggagcagtt aatgatgtac aagccatcgg
    13801 ggcattgttc agagatacag atgtgctggt gattgttgat gctataagcg gtctcatttc
    13861 tcatgagcta tcaatggatg attggggatt agacatcgta ttagcagcct ctcataaagg
    13921 atttatgatg ccgccgggcc tcgcttttgt tgctatttcg ccgaaagctt ggaagttgat
    13981 tgatgatgtt cagccttcca cttactattt ttcatttaaa agatttaaaa agttttatcc
    14041 tatggcgcct tcaagtccgg gtgtatcttt attattagca ttgaaaaagt cactagattt
    14101 attgaaagca gaaggccttt cgaatgcgac gaggcggcat gcccgtatcg ccagggcaac
    14161 gcaaaaagga ttggaagcat taggttttca cctttttgta caatctcctc atgtgagaag
    14221 tcatacagtg acagcagcgt tgactccatc gggaattgac gcagctctat tattacaaaa
    14281 actaaataaa gaatatgggc ttacgataac aggcggtcaa ggtgaattta aaggaaaaat
    14341 gatcaggatt gggcatattg gagctgttga tgaaatcgat ttgttcggaa tattcgggat
    14401 aatagagttg gtgttaacag aaatgggtta tcaggttcag cctgggacca gcatgactgc
    14461 tttgagtgaa gcattaggag cggaggtcat acaaaatgct taaattatat cagagggagc
    14521 catgtcctta ttgcaaaccg gtaagagaga agttaactga gctgaatgta acgtatatca
    14581 atgtaaacct tccgaaggat cggactttgc ggacagaatt aatagaaaaa acaggcgttc
    14641 cttatatacc cgctttaatt gatgaagaag ataatgtggt cattccaggc aagctggaat
    14701 acaaccagca tgtcttggat tatatagaaa aaaagtttgg ccaaaatcgt taagggggat
    14761 tctgcttctt gcgctatgcc ttcataacag atatacatgg gaaacgtaat aatcttgaaa
    14821 aggttttgga gcatatccaa gccttttctt ctatacatga gatcatttgt ttgggagatg
    14881 tttttgaagt taaggttcct aaaaaggatt taaaagattt tcagtttcag tccatagaac
    14941 aagttttaga tttggattgg gagttaattg atttgttaaa aggtatacga gtgataaaag
    15001 gcaatcaaga ggagaggata ttaagtctga tccctgagaa agaaattccg atagactttt
    15061 ataacttttt gactcacatg cctttagaca tttatttaac tccaatggtc agattaacgc
    15121 acggtcatac atttgactgg atggaggaag aagactattg gaggcccagc catattcatt
    15181 attggagcag accgtggatt ttttatggcc ataaccatca aaatgtactg tttgaagttc
    15241 aggagaaaaa gaatcatcct tattacgaac gaaaacacat tataaatggt aagcctatca
    15301 cattagacgc tgcatctcgt tatttgatca atataggtga tatgaaatat gatcacccta
    15361 gttggatgct tttggataca ttggaaaatc agattactta caatatattg tattgaaaag
    15421 gagtttattc tgatgcatcg tattctactc attaattccg ataaaccaga gcctattcag
    15481 ttttttcaaa aagataagga aacaaatgat acgatcaata tatctgtcat tacgagatcg
    15541 tgttatgctc ctctttattc acattggacg gatcatgtat acatcgttga tgatataaca
    15601 gatgtaacgg ttatgaagag tttgatgctt gagatattaa aagtggggcc aattgatcat
    15661 attgttacca caaccgaaaa gagtatatta acaggcgggt ttcttcgctc ttattttggg
    15721 atagccggtc ctgaatttga aacatctctt tatatgacga ataaattggc gatgaagaca
    15781 aaacttaaaa tggaagggat tcctgttgca gattttttgt gcttaagtca ggtagaagat
    15841 atccctgcag caggcgagaa actaggctgg cctataattg taaagccggc tcttggttcg
    15901 ggtgccttaa atacttttat aatcgaatcc ttacatcatt ttgaaagcct atattcaaca
    15961 tcggatggtt taggtgaact aaagaagaat aactctctta tgattgtcga aaaatgtata
    16021 gaaatggaag aatttcattg cgatacttta tacgctgacg gagagattct ttttgtatca
    16081 atatcaaaat atacagtgcc tttgctaaaa ggaatggcta aaatccaagg atcattcatt
    16141 ttaagtcaag atgatccgct ttatgctgaa atattagaac ttcagaagtc tgttgctcaa
    16201 gcatttcgaa tcacagacgg tcccgggcat cttgaaatat acagaactcc ttcaggtgaa
    16261 ttgatcgtcg gtgagattgc gatgcgcatt gggggcggag ggatcagccg catgatagaa
    16321 aaaaaattca atatttcttt atgggaaagt tctcttaacg cttccatagg taaagatcca
    16381 aatctcatgg tcaatccaat agaggggact gtcgggtact ttagcctgcc ttgccgaaac
    16441 ggaacaataa aagaatttac tcccattgag gactgggaaa agctcgatgg cataatggag
    16501 gttgaattgt tataccaaga aggtgatgtt gttgatgaaa agcaaagttc aagttttgat
    16561 ctggccagac tttatttttg tttagaaaat gagaatgaag tccagcatct attagcttta
    16621 gtcaaacaaa catattatct tcacgtaaca gaggatcata tgatgaatca ataaattcat
    16681 ttggatgttg ctgttgttta agtataaact ctgctgcata tagcaaaatg gtctagcagc
    16741 tatcgcgaag ttacagctcc attcatggaa ttatggcacc ggagatactg ggtggtttgt
    16801 gacagcgtca accgggcgta cattattaag taggcaagct gttcttgatg aacagcttat
    16861 tttttatgag gaacgatgaa atataaacaa ttacattata tctatataaa agaatgtaaa
    16921 taaagttcac aattcgaaac tacgaatata ggtgtttacc tgaaaaaaac aattgtattt
    16981 tccagagaaa tttattatga tgaaataagt aattttggag attatctaac aattttatga
    17041 ttgaattttc tgatattttc agcttgataa gaaatgaaga acgttttgga ggctggtcgg
    17101 ccttgatcct atttcggttg agctgtacat gtattcgttt ttaagaggag gaagcggagt
    17161 ggaaaataaa gaattgaaga gaggtttgag cgcccgtcat attcagatga ttgccttggg
    17221 cggcacgatc ggtgttggtt tatttatggg ttctgccagc acgatttcat ggactggccc
    17281 gtctgtcctt ctggcttatg cgatttgcgg aatttttatc ttttttatca tgcgtgcaat
    17341 gggtgaaatg ctgtatgtgg agccgagtac cggttctttt gcaaccttcg gccatcaata
    17401 cattcatccc cttgctggtt atatgacggc gtggagcaac tggttccagt ggattatcgt
    17461 cggcatgtca gaaattatcg cagtcggttc ttacatgaaa tattggttcc cggatttgcc
    17521 tgcttggata cctggtatcg tagctatggc aattctcggt gcggcgaact taatttctgt
    17581 taagtcgttt ggcgagtttg agttttggtt tgcgatgatt aaaatcgtga cgattatctt
    17641 aatgattatt gccggaatcg gaattatctt ctttggattt ggcaacggcg gagatgctat
    17701 cggtttgtct aatctgtggt ctcacggagg cttctttgcg ggcggtttct caggattttt
    17761 ctttgcattg tctctggtta ttgcggctta tcaaggggtt gagctgatcg ggattactgc
    17821 cggagaagca aaggacccgc aaaacacgct gcgcaacgcg attcaaagca ttatctggcg
    17881 tattttgatt ttctatatcg gtgctatttt tgtgatcgtg acggtatatc cttgggatga
    17941 gctgaattca cttggaagcc cgtttgtgtc tacgttttct aaagttggaa ttacagcagc
    18001 ggccggcatt attaactttg tcgttatcac ggcggcgatg tcaggctgca acagtgggat
    18061 tttcagcgcg ggacgtatgc tttatacatt aggtgtcaat ggacaggcac cgaaattctt
    18121 tgcgaagatt tctcgcaatg gtgtgccgct gtatggcaca atcgcggtgc tgatcggatt
    18181 agctgtcggc gttgtgctga actatgttgc gccgccgaag attttcgttt atgtatacag
    18241 cgcaagcgtg ctgccgggga tgattccttg gtttatcatt ttgatcagcc acctcggatt
    18301 cagaaaagcg aagggcgcgg cgttagataa acatccgttc aaaatgccgt ttgcaccttt
    18361 cacaaattat ttgacgattg ctttcttgct gatggttctt gtcggcatgt ggtttaatga
    18421 tgatactcgg atatctttaa ttgtaggggt tattttctta gctcttgtgg tcatcagtta
    18481 ttatgccttt ggaattggga agcgcgtgca ggcggatctt acaaaaagaa atcaagcagc
    18541 tgaataatat aggaaaaaga gacattgact gatgtctctt ttttcatttt ttgcgtatgg
    18601 atttttctca tttcagcaac ctataggata aagaacgaaa aggaaaggtg cttatactat
    18661 ggatgttaca ctcggttatt tgcgcgagtc actttcaaat catcttgaaa acgaagtctg
    18721 tctgcggatt tgcaagaaga tgctggcgaa gaggtatgcc aatgaagagg agtttgtaaa
    18781 ggatttggat gacgatgaga tgtcatattt gaatcaggtg ctggaaaagg aaattaagta
    18841 tgcccaagac gaacaggatc aaaaacgggc caaggaatta aatgaggtgt atgaattact
    18901 gctttgagaa aggcgggaat gaaattgggt gcgattgaac gaagcggtta tacgtttcag
    18961 ccggagtcta gtgtcgtccg gcaaaatggg gcgatccacg tgtatcatca tggagaattt
    19021 gttgaagaaa ttgaatttga gtttaacggg gattacccgg atcatgattt gattgaagag
    19081 cttgtgaatc attattgctt tgagcatgac atttaagagc cctgtacgtt tgcagggctc
    19141 attcatttat gaagtgatca ggccatattt ttttagaata tcaattgtga tgtttttggc
    19201 tgttgtaccg gagtcatcaa cattggtgac aaacgtatag gagccgtgct ctgttttgat
    19261 gaatccgaca aaccacccta atcccatgtc tgtcaggcgg gttccggttt tgccgtaaag
    19321 cgtataatga tctccttctt cttgaatcat catgcgtttg accgttttca tgaccgtttt
    19381 gtcaaacggg agcttctctt tgtaaagctt ctccataaag gcttcttgtt ccaacggaga
    19441 gattgtcaga gagctttgca gccaaaactg gtcgattccg ccgctgatat cttcgtttcc
    19501 gtatgacagg gtatgaagcc atgttttcat tcttttctcg ccgatgtccc tcgctaatgc
    19561 ctggtaatac cagatggcag attcccgcat ggctgagcca agtgtatggt cgcggttcca
    19621 tgattcgaat tcgcgtttga cgccatccca gcgtttgaca tcgtattcat cccggacggc
    19681 ttttacctgc aagccgatta aggcattggt cactttaaag gtagattgcg gagtttgtct
    19741 tttgttggcc cgttccttgt tgtagacaaa tgtcttatcc ttttctaaat catgaaggat
    19801 gaaggttccg tcagtatcct tgaactcctt atccacattt atccggctga cattcaggtg
    19861 cttttttgtt tcattggagg gcgcttttgc atgaacggac aaacctcctg tcacggcaat
    19921 gaccagcaca agaaaagcat atatccattt cttcattttg atctcccctt tgttttgatc
    19981 atctatcttt tctccatttc tgcttttcta cctttaaaag taatgaaaaa atgcttggaa
    20041 gcaaatactg taatggggtt tatcttcgtg agacaacgtg aaaacagaag taaaaaagga
    20101 aggcagggtt gcgggatgaa tgagcagatt ccacatgaca aaagcctcga taacagtgtg
    20161 gctttgatgc gggaaggata tttgtttata aagaatagaa aagagcatta ccattcggat
    20221 ttgttccaag cacgcttgct tggaaaaaca tttatttgta tgagcggcgc ggaggctgcg
    20281 aaggtatttt atgatacaga acgatttcag cggcagggtg ctctcccgaa acgagtgcag
    20341 aaatcgctgt ttggcgtcaa tgcaatccag acaatggatg gcgacgctca tattcatcgg
    20401 aagctgcttt ttctgt
//
